D:Barotrauma

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pChart

Disease Term
Synonyms Barotraumas
Documents 202
Hot Single Events 11
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Barotrauma. They are ordered first by their relevance to Barotrauma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT243214 Myst2 Negative_regulation of Gene_expression of Ptgs2 1 0.01 1.4 0.28 51.76
2 INT132792 IL4 Positive_regulation of IL6 4 0.28 1.81 0.47 5.00
3 INT179207 KCNAB2 Regulation of Gene_expression of ATP1A4 1 0.00 1.25 0.37 5.00
4 INT132801 IL4 Positive_regulation of Localization of IL6 2 0.26 1.47 0.26 5.00
5 INT353041 IL4 Positive_regulation of Localization of IL1B 1 0.02 0.99 0.16 5.00
6 INT353036 IL4 Positive_regulation of Localization of IL10 1 0.03 0.99 0.16 5.00
7 INT353040 IL4 Positive_regulation of IL8 1 0.02 0.99 0.16 5.00
8 INT353037 IL4 Positive_regulation of IL2 1 0.02 0.99 0.16 5.00
9 INT353038 IL4 Positive_regulation of Localization of IL2 1 0.02 0.99 0.16 5.00
10 INT353039 IL4 Positive_regulation of Localization of IL8 1 0.02 0.99 0.16 5.00
11 INT243216 Myst2 Positive_regulation of Gene_expression of VEGFA 1 0.00 0.75 0.11 5.00
12 INT243215 Myst2 Negative_regulation of Gene_expression of Icam1 1 0.01 0.68 0.1 5.00
13 INT243213 Myst2 Negative_regulation of Alms1 1 0.01 0.91 0.08 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Barotrauma. They are ordered first by their pain relevance and then by number of times they were reported in Barotrauma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT187062 Regulation of Pip 3 0.17 1.71 0.37 99.44
2 INT92343 Negative_regulation of CENPJ 20 0.57 6.25 0.2 98.48
3 INT193663 Binding of Pain1 9 0.36 8.84 8.04 98.22
4 INT92050 Negative_regulation of CUX1 1 0.21 1.91 0.44 97.16
5 INT125384 Positive_regulation of Pain1 23 0.49 17.1 14.83 97.14
6 INT179524 Negative_regulation of Pip 7 0.38 4.49 0.29 96.64
7 INT179216 Regulation of Gene_expression of KCNAB2 1 0.03 2.35 0.72 93.12
8 INT13880 Gene_expression of KCNAB2 3 0.27 2.95 1.38 92.68
9 INT23257 Regulation of CRP 127 0.62 100.05 21.87 89.24
10 INT74272 Localization of CPOX 39 0.63 25.12 10.53 89.20
11 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 87.20
12 INT24569 Negative_regulation of Pain1 26 0.41 21.82 21.08 77.76
13 INT284156 Positive_regulation of Negative_regulation of F2 1 0.01 1.71 0.15 76.72
14 INT17501 Negative_regulation of F2 70 0.58 32.23 7.51 76.72
15 INT987 Localization of TRH 37 0.78 10.53 11.1 73.52
16 INT23764 Regulation of Localization of TRH 4 0.45 0.75 1.4 73.52
17 INT61784 Positive_regulation of CENPJ 27 0.51 11.46 2.28 72.96
18 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 60.64
19 INT187061 Gene_expression of Pip 7 0.19 1.81 0.49 56.36
20 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 52.04
21 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 51.76
22 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 48.24
23 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 48.00
24 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 45.84
25 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97 45.84
26 INT144945 Negative_regulation of Icam1 27 0.50 26.23 7.08 44.96
27 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 43.72
28 INT153300 Negative_regulation of Gene_expression of CRP 48 0.58 39.97 7.58 43.36
29 INT179523 Binding of Pip 4 0.14 2.61 0.64 41.72
30 INT179219 Regulation of AMIGO2 1 0.09 3.88 1.3 41.68
31 INT107592 Gene_expression of SMG1 42 0.74 11.16 1.13 39.12
32 INT154732 Positive_regulation of Pip 7 0.41 5.93 0.6 35.88
33 INT10166 Localization of Tnf 237 0.81 153.95 88.64 35.44
34 INT10169 Positive_regulation of Localization of Tnf 44 0.70 27.71 16.75 35.44
35 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 32.72
36 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 26.84
37 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 26.40
38 INT10101 Binding of PLAT 24 0.36 12.62 2.78 24.72
39 INT22679 Binding of SERPINE1 25 0.36 17.33 2.36 24.72
40 INT161574 Localization of CENPJ 7 0.73 6.11 1.54 18.84
41 INT174590 Regulation of GLG1 5 0.27 5.54 0.72 7.80
42 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
43 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
44 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
45 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
46 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 5.00
47 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
48 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
49 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
50 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
51 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
52 INT50670 Gene_expression of CPOX 763 0.76 442.13 195.02 5.00
53 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
54 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 5.00
55 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 5.00
56 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
57 INT60694 Gene_expression of Il10 567 0.78 369.48 143.69 5.00
58 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
59 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
60 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
61 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
62 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
63 INT12082 Localization of IL6 365 0.81 241.78 105.78 5.00
64 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
65 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 5.00
66 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 5.00
67 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
68 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
69 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 5.00
70 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
71 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
72 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
73 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
74 INT48891 Positive_regulation of Il10 143 0.70 101.42 56.72 5.00
75 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
76 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 5.00
77 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
78 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
79 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 5.00
80 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 5.00
81 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
82 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
83 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 5.00
84 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
85 INT59466 Gene_expression of ISYNA1 204 0.77 112.57 35.48 5.00
86 INT53577 Negative_regulation of Localization of TNF 110 0.59 59.28 35.23 5.00
87 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
88 INT5489 Localization of CA2 172 0.80 39.46 33.56 5.00
89 INT10763 Localization of IL2 157 0.80 81.11 33.21 5.00
90 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
91 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 5.00
92 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 5.00
93 INT86437 Binding of IL6 154 0.48 121.22 29.3 5.00
94 INT22045 Gene_expression of IRF6 158 0.75 58.07 27.81 5.00
95 INT64499 Positive_regulation of IRF6 123 0.49 52.73 27.51 5.00
96 INT97 Negative_regulation of Adrb1 102 0.59 32.44 26.9 5.00
97 INT8518 Localization of Ifng 53 0.81 36.68 24.13 5.00
98 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 5.00
99 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 5.00
100 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
101 INT86751 Negative_regulation of Il10 62 0.59 40.1 20.51 5.00
102 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
103 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
104 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
105 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 5.00
106 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
107 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 5.00
108 INT70970 Binding of COPD 144 0.42 180.34 18.29 5.00
109 INT86673 Positive_regulation of Bcl2 77 0.70 57.74 17.37 5.00
110 INT24225 Gene_expression of Alms1 93 0.62 52.75 16.93 5.00
111 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 5.00
112 INT10834 Binding of IL8 65 0.48 41.66 16.53 5.00
113 INT74449 Positive_regulation of B4GALNT1 53 0.30 34.49 14.96 5.00
114 INT109535 Gene_expression of Vegfa 116 0.75 84.61 14.89 5.00
115 INT5207 Negative_regulation of Alms1 70 0.41 41.56 13.68 5.00
116 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 5.00
117 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
118 INT11793 Negative_regulation of CA2 78 0.57 19.63 12.35 5.00
119 INT145425 Positive_regulation of NLRP1 19 0.47 6.93 12.09 5.00
120 INT26973 Gene_expression of Tenc1 59 0.66 27.19 12 5.00
121 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
122 INT71766 Transcription of Il10 31 0.69 24.66 10.78 5.00
123 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
124 INT35460 Gene_expression of IL16 45 0.75 48.71 10.5 5.00
125 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28 5.00
126 INT88020 Positive_regulation of Fas 32 0.70 19.78 9.97 5.00
127 INT150867 Regulation of COPD 54 0.48 71.38 8.8 5.00
128 INT48860 Regulation of Localization of Tnf 25 0.61 20.68 8.78 5.00
129 INT28521 Gene_expression of HBG2 56 0.77 16.62 8.64 5.00
130 INT22771 Positive_regulation of Egf 44 0.70 16.45 8.64 5.00
131 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 5.00
132 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
133 INT43820 Positive_regulation of Twist1 75 0.59 42.15 8.47 5.00
134 INT86672 Negative_regulation of Bcl2 50 0.53 34.16 8.37 5.00
135 INT147793 Localization of COPD 70 0.64 89.01 7.3 5.00
136 INT10104 Negative_regulation of Edn1 43 0.59 15.63 7.2 5.00
137 INT10478 Protein_catabolism of Alms1 25 0.47 12.95 7.19 5.00
138 INT134967 Gene_expression of Ecm1 66 0.29 38.4 7.16 5.00
139 INT14903 Negative_regulation of SOD1 81 0.57 42.02 6.91 5.00
140 INT5864 Localization of IL36RN 19 0.44 14.5 6.87 5.00
141 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56 5.00
142 INT2442 Localization of Mb 38 0.80 24.74 6.33 5.00
143 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
144 INT81049 Positive_regulation of CASP1 44 0.67 19.97 5.69 5.00
145 INT77146 Binding of IL4 23 0.36 13.69 5.39 5.00
146 INT35536 Negative_regulation of CAT 26 0.57 14.39 5.38 5.00
147 INT89132 Regulation of NOS2 9 0.61 7.34 4.95 5.00
148 INT142162 Binding of IL10 30 0.37 21.9 4.84 5.00
149 INT55114 Gene_expression of CRS 42 0.58 26.86 4.69 5.00
150 INT35999 Positive_regulation of KCNAB2 6 0.65 5.12 4.31 5.00
151 INT94427 Positive_regulation of Positive_regulation of NOS2 14 0.47 11.15 4.3 5.00
152 INT108761 Localization of Alms1 24 0.70 13.92 3.74 5.00
153 INT123564 Negative_regulation of Rock2 13 0.59 9.61 3.58 5.00
154 INT16966 Positive_regulation of CRS 23 0.60 22.5 3.49 5.00
155 INT219695 Positive_regulation of Gene_expression of COPD 24 0.40 33.04 3.42 5.00
156 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 5.00
157 INT16969 Negative_regulation of CRS 28 0.37 14.77 3.35 5.00
158 INT65427 Regulation of Positive_regulation of Tnf 7 0.60 3.49 3.22 5.00
159 INT72126 Positive_regulation of HIST2H2AA3 16 0.38 3.94 2.89 5.00
160 INT177760 Negative_regulation of Gene_expression of IFN1@ 21 0.57 16.61 2.89 5.00
161 INT14902 Negative_regulation of XDH 38 0.55 24.19 2.86 5.00
162 INT167311 Gene_expression of Aqp5 8 0.61 1.77 2.75 5.00
163 INT22875 Regulation of CRS 16 0.39 14.33 2.69 5.00
164 INT93562 Negative_regulation of Localization of CA2 15 0.59 1.87 2.51 5.00
165 INT210527 Positive_regulation of Gene_expression of Tenc1 14 0.38 6.37 2.45 5.00
166 INT179225 Positive_regulation of AMIGO2 10 0.43 9.62 2.05 5.00
167 INT86671 Negative_regulation of Positive_regulation of Bcl2 6 0.57 3.83 2.03 5.00
168 INT142056 Binding of NLRP1 7 0.47 1.7 2.02 5.00
169 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 5.00
170 INT11136 Positive_regulation of Localization of Ifng 4 0.49 3.13 1.89 5.00
171 INT3866 Positive_regulation of Positive_regulation of INS 30 0.59 21.58 1.86 5.00
172 INT179222 Gene_expression of AMIGO2 7 0.66 7.68 1.77 5.00
173 INT182899 Transcription of IFN1@ 17 0.69 4.91 1.75 5.00
174 INT108978 Positive_regulation of CUX1 16 0.57 5.93 1.73 5.00
175 INT40857 Positive_regulation of MAOA 6 0.49 2.51 1.71 5.00
176 INT24768 Negative_regulation of Gene_expression of Edn1 10 0.43 2.85 1.48 5.00
177 INT95338 Positive_regulation of Positive_regulation of CASP1 9 0.49 4.61 1.43 5.00
178 INT16184 Negative_regulation of CHKB 20 0.53 10.61 1.42 5.00
179 INT179217 Positive_regulation of ATP1A4 2 0.11 0.91 1.34 5.00
180 INT73553 Gene_expression of Aqp1 23 0.67 4.65 1.34 5.00
181 INT103960 Gene_expression of ATP1A4 4 0.73 3.05 1.34 5.00
182 INT11137 Negative_regulation of Localization of Ifng 3 0.38 2.45 1.26 5.00
183 INT10196 Localization of Dclk2 7 0.25 1.19 1.13 5.00
184 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 5.00
185 INT177481 Negative_regulation of BBS2 6 0.31 5.34 1.06 5.00
186 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 5.00
187 INT185929 Regulation of Gene_expression of IRF6 9 0.20 1.66 0.99 5.00
188 INT109806 Positive_regulation of Ppl 3 0.25 2.46 0.99 5.00
189 INT29762 Negative_regulation of P4hb 4 0.21 1.41 0.86 5.00
190 INT32835 Negative_regulation of Pde3a 5 0.10 3.65 0.82 5.00
191 INT21246 Negative_regulation of ATP1A4 3 0.10 3.3 0.79 5.00
192 INT179213 Gene_expression of Aqp3 10 0.63 5.13 0.77 5.00
193 INT15783 Regulation of SMS 6 0.23 3.2 0.75 5.00
194 INT68589 Gene_expression of Cacna1c 14 0.58 6.36 0.69 5.00
195 INT55141 Gene_expression of P4hb 4 0.56 0.81 0.67 5.00
196 INT174986 Gene_expression of AIRN 20 0.57 6.13 0.64 5.00
197 INT180743 Binding of SARS 12 0.23 17.94 0.62 5.00
198 INT220316 Binding of Aliq1 4 0.10 5.71 0.61 5.00
199 INT127066 Gene_expression of Rip 6 0.64 1.8 0.6 5.00
200 INT210075 Positive_regulation of MIP 3 0.67 0.98 0.56 5.00
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