D:Bronchogenic Carcinoma

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Disease Term
Synonyms Bronchial Carcinoma, Bronchial Carcinomas, Bronchogenic Carcinomas, Carcinoma Bronchial, Carcinomas Bronchial, Carcinomas Bronchogenic
Documents 396
Hot Single Events 34
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Bronchogenic Carcinoma. They are ordered first by their relevance to Bronchogenic Carcinoma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT199787 gr Regulation of gr Regulation of CYP2C9 1 0.03 0.63 0 81.88
2 INT199801 gr Regulation of CYP2C9 1 0.08 0.63 0 81.88
3 INT182489 Gene_expression of AGTR2 Positive_regulation of Gene_expression of AGTR1 1 0.26 0.92 0.4 5.00
4 INT182497 IL1B Regulation of Localization of GH1 1 0.00 0.84 0.38 5.00
5 INT182492 IL1B Regulation of Gene_expression of IGF1 1 0.01 0.83 0.38 5.00
6 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 5.00
7 INT182494 TNF Positive_regulation of OLR1 1 0.05 2.51 0.13 5.00
8 INT175398 Binding of ERBB2 and VEGFA 2 0.16 1.34 0.13 5.00
9 INT175401 Binding of EGFR and VEGFA 2 0.13 1.49 0.13 5.00
10 INT182493 HGS Positive_regulation of OLR1 1 0.00 2.51 0.13 5.00
11 INT182496 AGT Positive_regulation of Phosphorylation of STAT3 1 0.03 0.79 0.12 5.00
12 INT182488 OLR1 Positive_regulation of OLR1 Positive_regulation of Gene_expression of AGTR1 1 0.00 1.27 0.07 5.00
13 INT182491 OLR1 Positive_regulation of HGS 1 0.00 1.22 0.07 5.00
14 INT302985 HIVEP1 Positive_regulation of Positive_regulation of AHR 1 0.06 0.5 0.06 5.00
15 INT302984 MBP Positive_regulation of AHR 1 0.31 0.3 0.06 5.00
16 INT282294 Binding of Gpt and BPIFA4P 1 0.02 0.47 0 5.00
17 INT213746 Binding of Pecam1 and Epc1 1 0.09 0 0 5.00
18 INT289510 Binding of ODF2 and Ezr 1 0.10 0.47 0 5.00
19 INT213747 Positive_regulation of Gtf3a Positive_regulation of Epc1 1 0.01 0 0 5.00
20 INT175400 RASGRP1 Positive_regulation of MAP3K5 1 0.00 1.2 0 5.00
21 INT175399 Binding of TP53 and SACM1L 1 0.00 2.37 0 5.00
22 INT213745 Binding of Kdr and Epc1 1 0.17 0 0 5.00
23 INT213744 Binding of Cd34 and Epc1 1 0.12 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Bronchogenic Carcinoma. They are ordered first by their pain relevance and then by number of times they were reported in Bronchogenic Carcinoma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT59900 Binding of MATN3 13 0.42 17.19 3.59 99.76
2 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.72
3 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 99.56
4 INT671 Positive_regulation of Cea 221 0.69 164.5 47.79 99.38
5 INT161097 Gene_expression of Epc1 36 0.45 7.76 1.64 98.24
6 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 98.08
7 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 98.08
8 INT101605 Gene_expression of Gsta 7 0.72 3.27 1.25 98.00
9 INT139366 Gene_expression of PROM1 98 0.77 67.84 3.39 97.72
10 INT199764 Positive_regulation of Gene_expression of Gstp1 1 0.55 2.21 0 97.08
11 INT24880 Positive_regulation of HRH2 7 0.69 1.34 2.74 96.92
12 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48 96.68
13 INT249 Localization of GHRH 215 0.80 78.02 51.87 95.32
14 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 93.92
15 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 93.92
16 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 88.96
17 INT10847 Gene_expression of LAMC2 39 0.75 27 12.09 88.28
18 INT127037 Gene_expression of Ppig 26 0.65 16.08 6.84 88.28
19 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 85.60
20 INT129006 Negative_regulation of Gstp1 1 0.34 1.85 0.65 85.44
21 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 85.04
22 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 85.04
23 INT7561 Positive_regulation of gr 70 0.57 31.92 20.22 84.80
24 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 84.76
25 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 84.76
26 INT22738 Negative_regulation of DYNLL1 17 0.57 6.68 2.06 84.24
27 INT289504 Negative_regulation of Dync2h1 1 0.27 1.04 0 84.24
28 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 84.12
29 INT71281 Positive_regulation of Gene_expression of CYP2C9 13 0.62 5.11 1.3 83.44
30 INT57922 Gene_expression of CYP2C9 65 0.78 22.24 7.53 83.04
31 INT104756 Gene_expression of ACSM3 8 0.58 8.76 1.83 82.76
32 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 81.44
33 INT20721 Localization of ACOT1 47 0.80 11.37 10.95 80.72
34 INT68372 Regulation of CYP2C9 28 0.62 5.64 9.53 80.04
35 INT100542 Regulation of Ppig 6 0.17 11.78 0.69 77.64
36 INT199781 Regulation of Regulation of Ppig 1 0.07 1.14 0 77.64
37 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 75.76
38 INT14132 Negative_regulation of HTR1A 25 0.57 4.93 10.91 75.00
39 INT214 Localization of AVP 370 0.81 208.51 91.09 75.00
40 INT95330 Gene_expression of Ephx1 4 0.67 6.72 0.7 73.76
41 INT44378 Gene_expression of GSTM1 69 0.76 34.61 8.81 73.76
42 INT31598 Gene_expression of Mgst1 41 0.78 6.44 6.3 73.76
43 INT195132 Gene_expression of Gsta2 6 0.56 4.12 0.49 73.76
44 INT199769 Gene_expression of Ugt2a1 1 0.52 2.77 0 73.76
45 INT199766 Gene_expression of Ppib 1 0.75 1.71 0 73.76
46 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 69.84
47 INT3151 Localization of MBP 27 0.80 7.58 2.28 69.64
48 INT73080 Positive_regulation of TTF1 4 0.38 2.37 0.14 67.24
49 INT85623 Gene_expression of ATXN1 6 0.58 5.14 0.9 67.20
50 INT199784 Positive_regulation of Gsta2 3 0.34 1.74 0.28 65.68
51 INT199798 Positive_regulation of BBS2 2 0.50 5.85 2.55 64.88
52 INT199762 Positive_regulation of Gstp1 2 0.55 2.02 0.32 63.20
53 INT4535 Localization of PROC 106 0.73 76.24 21.1 61.36
54 INT38673 Negative_regulation of KRT20 38 0.42 22.49 2.77 57.84
55 INT199790 Regulation of Gene_expression of CYP3A5 1 0.18 0.5 0.04 57.12
56 INT52905 Gene_expression of Cd4 84 0.78 45.68 12.75 56.88
57 INT121682 Gene_expression of CYP3A5 3 0.73 5.09 0.65 56.68
58 INT199782 Regulation of Ppib 1 0.26 0.44 0 56.40
59 INT48970 Positive_regulation of LILRB1 7 0.67 11.38 0.67 56.24
60 INT16568 Positive_regulation of HTR3A 14 0.67 4.82 6.01 55.04
61 INT48688 Positive_regulation of HTR4 12 0.67 1.94 2.81 55.04
62 INT30 Gene_expression of Gast 158 0.78 99 41.45 52.80
63 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 51.92
64 INT115982 Positive_regulation of KRT7 18 0.50 19.81 1.14 51.20
65 INT62763 Binding of GFER 3 0.48 0.66 0.06 50.00
66 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 47.08
67 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7 47.08
68 INT89925 Gene_expression of NR1I2 22 0.75 9.63 4.21 47.08
69 INT176208 Gene_expression of Nr1h2 27 0.59 22.75 3.84 47.08
70 INT147572 Gene_expression of Ahr 73 0.75 38.99 3.15 47.08
71 INT38013 Gene_expression of Casr 30 0.73 6.03 3.09 47.08
72 INT199797 Gene_expression of XPR1 1 0.02 1.7 0 47.08
73 INT2673 Negative_regulation of PROC 93 0.57 50.34 12.79 46.24
74 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 42.72
75 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 42.72
76 INT99550 Regulation of FLNA 51 0.54 27.88 2.58 39.16
77 INT174875 Gene_expression of Myl3 3 0.43 2.56 0.1 22.36
78 INT199774 Positive_regulation of Ephx1 1 0.40 1.63 0 21.60
79 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 19.20
80 INT108798 Negative_regulation of Positive_regulation of ALPP 9 0.25 4.26 1.46 19.20
81 INT157135 Positive_regulation of MKI67 10 0.60 7.51 0.28 16.20
82 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
83 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
84 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 5.00
85 INT252 Localization of GH1 529 0.80 227.4 122.05 5.00
86 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
87 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
88 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
89 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
90 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 5.00
91 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 5.00
92 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
93 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
94 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
95 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
96 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 5.00
97 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
98 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 5.00
99 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
100 INT157666 Positive_regulation of GOPC 335 0.60 120.19 42.75 5.00
101 INT56870 Gene_expression of CYP2D6 87 0.78 8.83 37.53 5.00
102 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
103 INT10796 Gene_expression of CYP2B6 131 0.77 30.14 35.27 5.00
104 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
105 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
106 INT62830 Gene_expression of VCAM1 149 0.78 125.23 32.4 5.00
107 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
108 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 5.00
109 INT6855 Binding of NCOR2 71 0.41 15.64 28.96 5.00
110 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
111 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 5.00
112 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 5.00
113 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 5.00
114 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 5.00
115 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
116 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 5.00
117 INT4877 Gene_expression of MME 184 0.78 122.82 24.78 5.00
118 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 5.00
119 INT27933 Gene_expression of NCOR2 65 0.72 31.35 24.23 5.00
120 INT35716 Positive_regulation of NCOR2 45 0.60 18 23.54 5.00
121 INT16721 Negative_regulation of Cat 56 0.59 44.44 22.84 5.00
122 INT5096 Positive_regulation of Gtf3a 79 0.60 42.26 20.62 5.00
123 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
124 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
125 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
126 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 5.00
127 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
128 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
129 INT61548 Positive_regulation of Fgf2 72 0.70 32.18 14.49 5.00
130 INT20665 Gene_expression of ACE 87 0.78 51.71 14.19 5.00
131 INT79703 Gene_expression of Agtr1a 46 0.76 14.18 13.77 5.00
132 INT17565 Regulation of Gpt 85 0.60 43.64 13.68 5.00
133 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
134 INT3962 Regulation of AGT 50 0.62 20.96 13.01 5.00
135 INT96850 Negative_regulation of CCL2 42 0.59 24.89 12.55 5.00
136 INT541 Positive_regulation of MBP 31 0.67 28.56 12.24 5.00
137 INT70555 Regulation of Pax3 13 0.35 3.62 12.05 5.00
138 INT53038 Positive_regulation of Agtr1a 35 0.67 23.76 11.68 5.00
139 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 5.00
140 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 5.00
141 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 5.00
142 INT71189 Gene_expression of Cyp1a2 24 0.78 11.39 11.12 5.00
143 INT62580 Gene_expression of Cyp2e1 31 0.78 15.4 11.08 5.00
144 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 5.00
145 INT15054 Gene_expression of Mme 48 0.77 42.52 10.63 5.00
146 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 5.00
147 INT17741 Gene_expression of MBP 67 0.78 23.67 9.65 5.00
148 INT28312 Gene_expression of ABCA1 85 0.72 37.69 9.27 5.00
149 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 5.00
150 INT82685 Gene_expression of Pecam1 36 0.76 27.95 9.01 5.00
151 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 5.00
152 INT61599 Positive_regulation of CYP2C9 43 0.69 11.1 8.33 5.00
153 INT725 Negative_regulation of IgG 62 0.41 37.21 8.16 5.00
154 INT29229 Regulation of NCOR2 20 0.42 5.75 8.08 5.00
155 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 5.00
156 INT71308 Gene_expression of CCL11 33 0.76 25.66 7.83 5.00
157 INT90603 Positive_regulation of Ahr 103 0.69 58.65 7.73 5.00
158 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
159 INT182750 Gene_expression of Hmgcr 61 0.58 17.23 7.4 5.00
160 INT83006 Gene_expression of AGTR1 59 0.75 54.46 7.27 5.00
161 INT14637 Negative_regulation of MBP 19 0.43 7.06 7.18 5.00
162 INT42038 Localization of ACE 26 0.80 8.88 7.06 5.00
163 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
164 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 5.00
165 INT43415 Gene_expression of CYP4A11 11 0.56 7.65 5.94 5.00
166 INT21609 Positive_regulation of RASGRP1 58 0.50 40.78 5.47 5.00
167 INT213741 Gene_expression of Kdr 60 0.75 44.24 5.35 5.00
168 INT102891 Positive_regulation of AGTR1 31 0.67 30.57 5.29 5.00
169 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
170 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 5.00
171 INT127914 Gene_expression of AGTR2 23 0.68 26.87 4.69 5.00
172 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 5.00
173 INT65881 Gene_expression of CYP2C19 21 0.76 1.19 4.57 5.00
174 INT73503 Positive_regulation of Gene_expression of IL13 16 0.37 14.6 4.23 5.00
175 INT9349 Gene_expression of BBS2 15 0.49 12.77 4.22 5.00
176 INT21406 Negative_regulation of Gene_expression of IgG 20 0.41 9.36 3.58 5.00
177 INT536 Binding of MBP 17 0.48 6.52 3.56 5.00
178 INT85130 Regulation of IL5 14 0.27 8.37 3.55 5.00
179 INT73463 Positive_regulation of Gene_expression of TSC1 20 0.38 14.59 3.53 5.00
180 INT115921 Positive_regulation of AHR 22 0.49 12.03 3.53 5.00
181 INT38303 Binding of Gpt 21 0.47 15.84 3.43 5.00
182 INT105884 Binding of Bcl2 19 0.35 15.67 3 5.00
183 INT8103 Binding of TP53 46 0.44 40.2 2.96 5.00
184 INT94437 Positive_regulation of Gene_expression of OLR1 17 0.70 16.04 2.8 5.00
185 INT44661 Regulation of Ahr 15 0.45 12.69 2.79 5.00
186 INT22212 Gene_expression of CYP1A1 34 0.76 10.11 2.77 5.00
187 INT152434 Localization of CCL11 6 0.78 9.47 2.68 5.00
188 INT70273 Gene_expression of CALB2 9 0.75 7.85 2.54 5.00
189 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
190 INT101342 Negative_regulation of CYP2A6 11 0.53 3.68 2.39 5.00
191 INT191221 Positive_regulation of Amigo2 20 0.12 24.24 2.31 5.00
192 INT22984 Positive_regulation of FRTS 12 0.67 5.24 2.25 5.00
193 INT115193 Positive_regulation of Phosphorylation of STAT3 30 0.64 11.37 2.2 5.00
194 INT21611 Negative_regulation of RASGRP1 20 0.35 11.76 2.15 5.00
195 INT38674 Regulation of KRT20 32 0.44 19 2.15 5.00
196 INT179256 Positive_regulation of Localization of IL13 7 0.42 7.04 2.14 5.00
197 INT65207 Positive_regulation of Positive_regulation of Fgf2 10 0.70 3.5 2.08 5.00
198 INT70878 Gene_expression of CYP2A6 17 0.75 4.25 2.02 5.00
199 INT36267 Positive_regulation of CYP1A1 29 0.69 11.09 2.01 5.00
200 INT32431 Gene_expression of HTC2 17 0.75 9.72 1.93 5.00
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