D:Calciphylaxis

Disease Term Synonyms Calciphylaxes Documents 118 Hot Single Events 36 Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Calciphylaxis. They are ordered first by their relevance to Calciphylaxis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT90387	ROS1 Positive_regulation of NFKB1	4	0.32	2.35	0.87	50.00
2	INT182771	ROS1 Positive_regulation of NFKB1 Positive_regulation of CRP	1	0.00	3.83	0.28	50.00
3	INT182772	ROS1 Positive_regulation of NFKB1 Positive_regulation of IL1B	1	0.00	1.89	0.14	50.00
4	INT182773	ROS1 Positive_regulation of NFKB1 Positive_regulation of IL6	1	0.00	1.9	0.14	50.00
5	INT182780	NFKB1 Positive_regulation of IL1B	1	0.00	1.8	0.14	50.00
6	INT182782	NFKB1 Positive_regulation of IL6	1	0.00	1.8	0.14	50.00
7	INT182775	Binding of PTH and ROS1	1	0.04	1.73	0.04	50.00
8	INT182784	IGF1 Positive_regulation of Gene_expression of INS	1	0.02	1.87	0	50.00
9	INT182804	Binding of ETV3 and T2DM	1	0.10	2.62	0	50.00
10	INT182778	IGF1 Positive_regulation of Gene_expression of ETV3	1	0.03	1.89	0	50.00
11	INT182774	Binding of ETV3 and SAE1	1	0.00	1.17	0	50.00
12	INT182783	INS Positive_regulation of Gene_expression of ETV3	1	0.01	1.89	0	50.00
13	INT182777	IAPP Positive_regulation of Gene_expression of ETV3	1	0.06	1.88	0	50.00
14	INT182776	IAPP Positive_regulation of Gene_expression of INS	1	0.03	1.87	0	50.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Calciphylaxis. They are ordered first by their pain relevance and then by number of times they were reported in Calciphylaxis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT182794	Gene_expression of CPLX1	1	0.06	5.57	0.17	100.00
2	INT182791	Binding of CPLX1	1	0.04	2.85	0.3	100.00
3	INT182799	Positive_regulation of Gene_expression of CPLX1	1	0.04	1.49	0.03	100.00
4	INT182792	Regulation of STS	4	0.47	2.91	0.61	100.00
5	INT182801	Positive_regulation of CPLX1	1	0.04	2.92	0.03	100.00
6	INT182788	Gene_expression of ETV3	8	0.40	11.33	0.36	99.84
7	INT158409	Gene_expression of T2DM	3	0.65	9.58	0.56	99.84
8	INT744	Positive_regulation of PTH	130	0.70	95.02	11.7	99.48
9	INT6512	Gene_expression of PTH	103	0.77	76.29	6.33	98.96
10	INT82166	Regulation of NOS3	14	0.54	7.57	2.08	98.94
11	INT76091	Positive_regulation of NOS3	48	0.61	18.4	7.92	98.74
12	INT182753	Positive_regulation of Binding of	1	0.49	1.88	0	98.72
13	INT131019	Binding of T2DM	6	0.47	6.97	0.31	98.72
14	INT182787	Binding of ETV3	14	0.37	25.44	0.37	98.48
15	INT182786	Positive_regulation of Binding of ETV3	1	0.12	1.88	0	98.48
16	INT703	Positive_regulation of Pth	177	0.70	127.09	27.26	97.80
17	INT16389	Gene_expression of Plg	80	0.67	36.88	6.74	97.64
18	INT3952	Negative_regulation of ALB	116	0.59	72.18	18.35	97.00
19	INT1127	Negative_regulation of IGHG3	32	0.28	21.1	7.37	97.00
20	INT1124	Negative_regulation of CD40LG	53	0.57	36.26	7	97.00
21	INT1126	Negative_regulation of CD79A	46	0.59	31.07	6	97.00
22	INT35143	Negative_regulation of ANGPTL5	28	0.54	18.59	3.14	97.00
23	INT62570	Binding of Pth	48	0.48	26.45	4.85	96.40
24	INT59194	Gene_expression of STS	18	0.59	6.74	1.89	96.08
25	INT83201	Gene_expression of NOS3	93	0.78	47.16	12.48	95.08
26	INT62895	Gene_expression of NOSTRIN	51	0.75	28.8	10.68	94.80
27	INT99289	Localization of STS	8	0.79	6.5	0.92	94.00
28	INT89484	Gene_expression of TNFRSF11B	119	0.76	53.57	19.67	91.92
29	INT6625	Negative_regulation of Pth	96	0.58	57.6	8.24	90.12
30	INT3038	Gene_expression of INS	1583	0.78	1174.16	107.01	89.36
31	INT16960	Gene_expression of Crp	166	0.76	116.21	34.07	88.44
32	INT26996	Positive_regulation of Gene_expression of Crp	21	0.68	21.55	2.75	88.44
33	INT130176	Positive_regulation of Gene_expression of CRP	125	0.66	137.06	25.9	88.20
34	INT17612	Gene_expression of CRP	676	0.78	580.61	119.03	87.92
35	INT154702	Regulation of Positive_regulation of Pth	1	0.43	0.71	0.09	83.68
36	INT87517	Gene_expression of LDLR	73	0.69	37.35	3.32	82.92
37	INT19250	Positive_regulation of TAL1	3	0.25	2.51	1.4	78.88
38	INT69440	Gene_expression of ROS1	752	0.78	477.64	103.83	75.00
39	INT30738	Negative_regulation of Gene_expression of ALB	32	0.59	19.01	5.04	75.00
40	INT3758	Gene_expression of ALB	326	0.78	184.65	38.75	75.00
41	INT57562	Gene_expression of GLA	52	0.77	24.62	6.14	75.00
42	INT3824	Negative_regulation of PTH	40	0.59	28.58	3.39	60.92
43	INT60526	Gene_expression of IL10	449	0.78	292.71	107.84	50.00
44	INT18009	Positive_regulation of CRP	518	0.70	553.03	103.74	50.00
45	INT54571	Positive_regulation of NFKB1	263	0.70	138.99	87.32	50.00
46	INT17401	Gene_expression of IGF1	475	0.78	232.18	62.07	50.00
47	INT9408	Positive_regulation of Crp	296	0.69	242.27	57.35	50.00
48	INT1199	Positive_regulation of INS	579	0.70	399.64	50.43	50.00
49	INT69437	Positive_regulation of ROS1	328	0.58	222.83	40.56	50.00
50	INT74563	Positive_regulation of Gene_expression of ROS1	258	0.61	168.18	34.08	50.00
51	INT6624	Gene_expression of Pth	135	0.76	110.27	27.54	50.00
52	INT100861	Binding of CRP	179	0.48	175.2	26.45	50.00
53	INT9682	Positive_regulation of IGF1	238	0.70	120.03	26.36	50.00
54	INT37541	Gene_expression of SPP1	113	0.77	68.54	11.35	50.00
55	INT94784	Binding of ROS1	113	0.40	71.57	10.26	50.00
56	INT16130	Binding of IGF1	67	0.48	27.43	2.95	50.00
57	INT22715	Positive_regulation of Gene_expression of Pth	29	0.64	22.53	2.31	50.00
58	INT12618	Positive_regulation of IAPP	54	0.68	32.03	2.29	50.00
59	INT18844	Binding of IAPP	11	0.36	11.01	1.45	50.00
60	INT6514	Positive_regulation of Gene_expression of PTH	28	0.67	30.28	1.37	50.00
61	INT158540	Negative_regulation of HTN1	4	0.34	7.25	1.22	50.00
62	INT158542	Gene_expression of HTN1	10	0.75	10.69	1.07	50.00
63	INT158541	Positive_regulation of Gene_expression of HTN1	3	0.40	5.88	0.97	50.00
64	INT182790	Positive_regulation of SAE1	3	0.49	3.18	0.39	50.00
65	INT42244	Regulation of Gene_expression of PTH	5	0.45	3.95	0.34	50.00
66	INT182752	Negative_regulation of T2DM	1	0.41	2.06	0.29	50.00
67	INT121834	Gene_expression of IAPP	24	0.66	20.96	0.26	50.00
68	INT6604	Binding of ITGA3	3	0.14	3.37	0.22	50.00
69	INT129762	Binding of HTN1	5	0.03	5.68	0.19	50.00
70	INT182800	Positive_regulation of ETV3	5	0.46	10.01	0.14	50.00
71	INT182785	Gene_expression of NHEJ1	1	0.01	1.08	0.06	50.00
72	INT182754	Positive_regulation of T2DM	1	0.67	4.5	0.03	50.00
73	INT105572	Negative_regulation of TAL1	3	0.23	1.05	0.06	35.96
74	INT16478	Positive_regulation of Plg	29	0.45	18.07	4.07	5.00
75	INT17326	Binding of Plg	14	0.43	11.72	1.94	5.00
76	INT173508	Negative_regulation of Fgfr1	4	0.55	5.08	0.66	5.00