D:Carcinoma In Situ

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Disease Term
Synonyms CARCINOMA INTRAEPITHELIAL, Carcinoma Preinvasive, Intraepithelial Carcinoma, Intraepithelial Neoplasm, INTRAEPITHELIAL NEOPLASMS, Neoplasm Intraepithelial, Neoplasms Intraepithelial, Preinvasive Carcinoma
Documents 239
Hot Single Events 105
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Carcinoma In Situ. They are ordered first by their relevance to Carcinoma In Situ and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT272441 Binding of IFNA2 and Slc11a1 1 0.02 0.97 0 96.32
2 INT253935 Binding of PTPLA and Trpv1 1 0.14 1.25 0.65 92.92
3 INT94523 Binding of MT2A and ALG1 1 0.16 0.72 0.09 75.84
4 INT325952 Gene_expression of Ezr Positive_regulation of Mapk1 1 0.02 1.69 0.15 74.56
5 INT187575 TP53 Regulation of Gene_expression of Birc5 1 0.05 1.1 0 74.24
6 INT187576 BAX Regulation of Gene_expression of Birc5 1 0.06 1.1 0 73.96
7 INT187574 Binding of TP53 and Birc5 1 0.04 1.27 0 61.48
8 INT197552 GSTK1 Positive_regulation of NQO1 1 0.09 1.06 0 60.16
9 INT304023 SFRP1 Regulation of Binding of MSI1 1 0.04 1.78 0 58.48
10 INT304016 SFRP4 Regulation of Binding of MSI1 1 0.04 1.78 0 58.48
11 INT318192 MUC5AC Negative_regulation of Gene_expression of VEGFA 1 0.20 0.98 0.1 56.88
12 INT318210 MUC5AC Negative_regulation of Phosphorylation of Flt1 1 0.07 0.98 0.09 55.96
13 INT259095 Binding of RBBP8 and LMO4 1 0.15 0.73 0 51.64
14 INT259093 Binding of TSC1 and LMO4 1 0.02 0.74 0 51.64
15 INT259091 Binding of BRCA1 and LMO4 1 0.24 0.74 0 51.64
16 INT197547 Binding of PTS and KEAP1 1 0.08 1.23 0 46.88
17 INT318185 MUC5AC Positive_regulation of Gene_expression of MMP3 1 0.09 0.86 0.13 42.48
18 INT286650 Binding of IGHG3 and OLR1 1 0.01 0.42 0 28.00
19 INT83425 Binding of CD40LG and IGHG3 11 0.21 4.56 2.09 26.08
20 INT286653 Binding of CD40LG and OLR1 1 0.08 0.41 0 26.08
21 INT304020 AR Regulation of TP53 1 0.24 1.11 0 18.64
22 INT304028 MDM2 Regulation of TP53 1 0.19 1.11 0 18.64
23 INT304014 Binding of MSI1 and SGCG 1 0.00 1.92 0 17.24
24 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33 5.00
25 INT188196 LIF Regulation of MAPK1 1 0.21 2.26 0.87 5.00
26 INT188214 OSM Regulation of MAPK1 1 0.20 2.27 0.87 5.00
27 INT144035 IL6 Positive_regulation of STAT3 4 0.31 2.58 0.56 5.00
28 INT108332 EGF Positive_regulation of Phosphorylation of MAPK1 5 0.48 1.85 0.45 5.00
29 INT188194 OSM Regulation of IL6 1 0.16 1.12 0.43 5.00
30 INT188205 OSM Regulation of LIF 1 0.09 1.12 0.43 5.00
31 INT188211 IL6 Regulation of MAPK1 1 0.16 1.13 0.43 5.00
32 INT188207 LIF Regulation of IL6 1 0.17 1.12 0.43 5.00
33 INT327727 Atp6v0a2 Negative_regulation of Gene_expression of Kit 1 0.05 0.83 0.41 5.00
34 INT188193 Negative_regulation of EGF Positive_regulation of MAPK1 1 0.28 0.54 0.34 5.00
35 INT188204 Negative_regulation of IL6 Positive_regulation of STAT3 1 0.28 0.54 0.34 5.00
36 INT156831 EGF Positive_regulation of MAPK1 2 0.45 0.27 0.33 5.00
37 INT101810 Binding of NFE2L2 and KEAP1 7 0.53 4.12 0.29 5.00
38 INT101813 KEAP1 Negative_regulation of NFE2L2 3 0.47 1.63 0.28 5.00
39 INT262809 Il10 Positive_regulation of Regulation of Slc11a1 1 0.17 1.12 0.27 5.00
40 INT262810 Slc11a1 Positive_regulation of Gene_expression of Il10 1 0.20 0.97 0.27 5.00
41 INT188209 OSM Positive_regulation of MAPK1 1 0.35 0.47 0.27 5.00
42 INT241401 VEGFA Positive_regulation of Gene_expression of Gopc 1 0.11 0.85 0.25 5.00
43 INT188200 IL6ST Positive_regulation of STAT3 1 0.25 0.38 0.23 5.00
44 INT188195 GOPC Positive_regulation of MAPK1 2 0.21 0.32 0.22 5.00
45 INT318189 MUC5AC Regulation of Gene_expression of VEGFA 1 0.21 1.17 0.22 5.00
46 INT188203 EGF Positive_regulation of Protein_catabolism of OSM 1 0.30 0.17 0.21 5.00
47 INT188201 OSM Positive_regulation of Phosphorylation of STAT3 1 0.40 0.24 0.21 5.00
48 INT318211 MUC5AC Positive_regulation of Muc4 1 0.17 1.12 0.17 5.00
49 INT318188 MUC5AC Positive_regulation of MUC1 1 0.16 1.12 0.17 5.00
50 INT232005 Binding of Cd36 and Tsp1 2 0.25 1.81 0.16 5.00
51 INT188199 IL6 Positive_regulation of MAPK1 1 0.27 0.25 0.16 5.00
52 INT318209 Sis Negative_regulation of VEGFA 1 0.00 1.09 0.14 5.00
53 INT188197 LIF Positive_regulation of STAT3 1 0.35 0.27 0.12 5.00
54 INT188198 OSM Positive_regulation of STAT3 1 0.52 0.24 0.12 5.00
55 INT188202 HBE1 Positive_regulation of MAPK1 1 0.01 0.14 0.11 5.00
56 INT188192 HBE1 Positive_regulation of LY6E 1 0.00 0.14 0.11 5.00
57 INT172568 Gene_expression of GNRH1 Regulation of Localization of CGA 1 0.05 0.66 0.08 5.00
58 INT188210 EGF Positive_regulation of OSM 1 0.28 0 0.07 5.00
59 INT188208 EGF Regulation of STAT3 1 0.46 0 0.07 5.00
60 INT325954 Binding of Cttn and Ezr 1 0.22 1.61 0.07 5.00
61 INT241400 Epas1 Positive_regulation of Gene_expression of VEGFA 1 0.03 1.09 0.07 5.00
62 INT197553 Binding of NFE2L2 and LILRA3 1 0.03 0.43 0.06 5.00
63 INT278454 CSF2 Regulation of Hand2 1 0.02 0.66 0.05 5.00
64 INT318186 MUC5AC Positive_regulation of Gene_expression of VEGFA 1 0.22 1.01 0.04 5.00
65 INT213903 Binding of EGFR and ERBB2 10 0.37 5.03 0.04 5.00
66 INT197546 NFE2L2 Regulation of Gene_expression of ABCC2 1 0.17 0.72 0.04 5.00
67 INT318191 INCENP Negative_regulation of Gene_expression of VEGFA 1 0.00 1.05 0.03 5.00
68 INT318190 Negative_regulation of MUC5AC Negative_regulation of Gene_expression of VEGFA 1 0.23 1.06 0.03 5.00
69 INT318187 Binding of INCENP and MUC5AC 1 0.00 1.03 0.03 5.00
70 INT325945 Binding of Cd44 and Ezr 1 0.25 0.39 0 5.00
71 INT304029 Binding of PTEN and TP53 1 0.35 0.62 0 5.00
72 INT337062 Binding of VEGFA and NMI 1 0.07 1.12 0 5.00
73 INT266925 Regulation of Binding of EGFR and ERBB2 1 0.26 0.5 0 5.00
74 INT325942 Binding of Icam1 and Ezr 1 0.15 0.39 0 5.00
75 INT232006 Binding of Trp53 and Tsp1 1 0.06 0.75 0 5.00
76 INT325949 Binding of Spn and Ezr 1 0.14 0.39 0 5.00
77 INT304022 Binding of PIK3CG and TP53 1 0.10 0.72 0 5.00
78 INT325948 Ezr Regulation of Pcx 1 0.00 0.84 0 5.00
79 INT304012 Binding of AKT1 and PIK3CA 1 0.28 1.14 0 5.00
80 INT304018 Regulation of Binding of PIK3CG and TP53 1 0.12 0.73 0 5.00
81 INT197576 Loh1 Positive_regulation of NFE2L2 1 0.49 1.1 0 5.00
82 INT232004 Mapk8 Positive_regulation of Transcription of Fasl 1 0.05 0.65 0 5.00
83 INT286988 Twist1 Positive_regulation of EGFR 1 0.17 2.01 0 5.00
84 INT304025 Binding of PIK3CA and TP53 1 0.30 0.67 0 5.00
85 INT197544 Binding of KEAP1 and KLHL2 1 0.02 0.43 0 5.00
86 INT304015 Binding of PIK3CA and PIK3CG 1 0.09 0.67 0 5.00
87 INT259092 TSC1 Positive_regulation of Gene_expression of TCEAL1 1 0.01 4.58 0 5.00
88 INT278446 Binding of EGFR and EMR1 1 0.00 0.75 0 5.00
89 INT286651 OLR1 Positive_regulation of PRKCA 1 0.14 0.5 0 5.00
90 INT325953 Ezr Positive_regulation of Mapk1 1 0.02 0.4 0 5.00
91 INT331883 Binding of MAGEA4 and GOPC 1 0.03 0 0 5.00
92 INT304019 Binding of AKT1 and TP53 1 0.27 0.72 0 5.00
93 INT325955 Ezr Regulation of Mia1 1 0.09 1.68 0 5.00
94 INT304026 Binding of PIK3CG and PTEN 1 0.11 0.62 0 5.00
95 INT194362 PDGFA Regulation of EGFR 1 0.23 1.56 0 5.00
96 INT325946 Gene_expression of Ezr Positive_regulation of Positive_regulation of Mapk1 1 0.02 0.28 0 5.00
97 INT197545 KEAP1 Regulation of NFE2L2 3 0.49 0.8 0 5.00
98 INT232003 Cd36 Positive_regulation of Transcription of Fasl 1 0.10 0.66 0 5.00
99 INT305350 Pten Regulation of Phosphorylation of Akt1 1 0.05 0.95 0 5.00
100 INT325947 Ezr Regulation of Zfp369 1 0.00 0.84 0 5.00
101 INT305336 TP53 Negative_regulation of Phosphorylation of RB1 1 0.29 0.96 0 5.00
102 INT304027 Negative_regulation of PTEN Positive_regulation of Positive_regulation of AKT1 1 0.32 1.86 0 5.00
103 INT325950 Binding of Icam2 and Ezr 1 0.17 0.39 0 5.00
104 INT304017 Regulation of Binding of AKT1 and TP53 1 0.32 0.73 0 5.00
105 INT259094 STK11 Positive_regulation of Gene_expression of TCEAL1 1 0.18 5.5 0 5.00
106 INT232007 Ahsa1 Positive_regulation of Transcription of Fasl 1 0.03 0.65 0 5.00
107 INT194361 VEGFA Regulation of EGFR 1 0.22 1.58 0 5.00
108 INT304013 Binding of SUZ12 and JAZF1 1 0.30 1.89 0 5.00
109 INT339217 MMP9 Negative_regulation of VEGFA 1 0.05 0.38 0 5.00
110 INT304024 Binding of AKT1 and PTEN 1 0.33 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Carcinoma In Situ. They are ordered first by their pain relevance and then by number of times they were reported in Carcinoma In Situ. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 100.00
2 INT12861 Gene_expression of Cish 40 0.57 23.01 8.48 100.00
3 INT12628 Binding of Cish 4 0.30 2.45 0.78 100.00
4 INT258435 Binding of Serpinb1c 3 0.24 2.43 0.07 100.00
5 INT163592 Localization of CISH 5 0.54 5.9 1.26 100.00
6 INT187778 Gene_expression of Slc11a1 12 0.33 7.37 0.35 99.96
7 INT199138 Gene_expression of MT3 1 0.78 4.07 0.3 99.84
8 INT214025 Negative_regulation of INVS 4 0.07 3.36 0 99.76
9 INT116465 Gene_expression of Birc5 241 0.78 192.31 15.32 99.62
10 INT182312 Positive_regulation of Gene_expression of Birc5 26 0.69 25.3 2.32 99.62
11 INT116463 Negative_regulation of Gene_expression of Birc5 40 0.59 33.99 2.74 99.62
12 INT91754 Gene_expression of Cp 42 0.77 21.97 5.38 99.32
13 INT195106 Positive_regulation of Gene_expression of Cp 5 0.50 2.96 0.49 99.32
14 INT94538 Gene_expression of ALG1 1 0.37 3.6 0.31 99.24
15 INT94526 Positive_regulation of Gene_expression of ALG1 1 0.33 1.9 0.15 99.24
16 INT62684 Negative_regulation of TP53 66 0.58 66.09 4.62 99.14
17 INT78199 Gene_expression of Neu1 65 0.75 62.88 7.16 99.08
18 INT229677 Binding of Pan3 1 0.01 1.44 0.21 99.00
19 INT133193 Positive_regulation of TERT 16 0.50 6.43 1.38 98.56
20 INT48792 Regulation of ERBB2 48 0.57 36.56 1.8 98.52
21 INT134298 Gene_expression of Ptges2 96 0.54 56.52 17.19 98.48
22 INT259113 Gene_expression of LMO4 1 0.78 71.49 0.76 98.28
23 INT17881 Gene_expression of LEP 278 0.78 221.61 48.31 98.24
24 INT98739 Gene_expression of Fbrs 6 0.52 4.77 0.4 98.24
25 INT94774 Regulation of CDKN2A 43 0.60 44.41 13.99 97.96
26 INT86370 Regulation of CDH1 10 0.54 13.89 0.7 97.76
27 INT24042 Gene_expression of MUC5AC 98 0.77 74.99 6.18 97.68
28 INT75908 Regulation of LEP 77 0.60 60.16 15.19 97.08
29 INT325930 Gene_expression of Ezr 75 0.77 59.77 4.06 96.56
30 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 96.32
31 INT199134 Negative_regulation of Transcription of MT3 1 0.37 1.17 0.09 95.72
32 INT282576 Negative_regulation of Gene_expression of POU5F1 12 0.43 2.79 0.16 95.38
33 INT199139 Transcription of MT3 1 0.69 1.96 0.17 95.28
34 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 95.22
35 INT116879 Gene_expression of MAGEA4 3 0.41 5.82 0.47 95.22
36 INT331886 Gene_expression of DDX4 1 0.12 2.38 0 95.22
37 INT71906 Regulation of Gene_expression of ESR1 22 0.41 11.01 0.98 95.16
38 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 94.92
39 INT103824 Positive_regulation of SOD2 26 0.70 17.42 7.17 94.64
40 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 94.48
41 INT11941 Binding of Slc11a1 3 0.14 2.18 0.35 94.40
42 INT246978 Binding of PTPLA 3 0.18 3.62 2.79 94.28
43 INT325940 Positive_regulation of Gene_expression of Ezr 42 0.69 27.79 1.56 94.04
44 INT182313 Regulation of Gene_expression of Birc5 18 0.60 15.34 0.96 93.36
45 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 93.36
46 INT180578 Regulation of HEYL 3 0.06 3.15 0.49 93.16
47 INT4830 Binding of Trpv1 158 0.48 45.11 84.2 92.92
48 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 92.36
49 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 92.36
50 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 91.80
51 INT21788 Positive_regulation of ERBB2 49 0.66 28.88 1.68 91.80
52 INT266927 Positive_regulation of Transcription of ERBB2 2 0.46 2.5 0.03 91.80
53 INT250698 Positive_regulation of Transcription of TP53 3 0.18 3.68 0 91.80
54 INT94438 Gene_expression of OLR1 86 0.78 80.38 11.03 91.64
55 INT55952 Transcription of TP53 16 0.61 12.14 2.36 91.48
56 INT94534 Gene_expression of MT2A 8 0.75 11.28 1.76 91.36
57 INT181787 Transcription of ERBB2 13 0.71 10.03 0.16 91.28
58 INT172479 Positive_regulation of NFE2L2 74 0.70 35.22 0.79 91.24
59 INT49803 Negative_regulation of MUC1 37 0.58 26.37 2.06 91.20
60 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88 89.76
61 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41 89.76
62 INT272440 Negative_regulation of Slc11a1 1 0.02 0.81 0 89.56
63 INT19795 Positive_regulation of EGFR 161 0.70 103.69 11.55 89.32
64 INT94524 Gene_expression of MT1A 6 0.39 1.66 1.75 89.20
65 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 89.12
66 INT251628 Negative_regulation of CDKN2D 2 0.15 1.83 0 89.12
67 INT281250 Negative_regulation of Negative_regulation of CDKN2D 1 0.08 1.49 0 89.12
68 INT94527 Gene_expression of MT1B 2 0.36 1.2 0.11 88.92
69 INT197568 Regulation of NFE2L2 17 0.59 7.85 0.15 88.72
70 INT281251 Negative_regulation of LAMTOR1 1 0.12 1.42 0 88.72
71 INT281253 Negative_regulation of Negative_regulation of LAMTOR1 1 0.09 1.49 0 88.72
72 INT67589 Gene_expression of MT1E 8 0.51 7.52 1.09 88.64
73 INT20006 Gene_expression of MT1F 27 0.68 19.55 3.18 88.36
74 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 88.32
75 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0 88.32
76 INT318207 Negative_regulation of Negative_regulation of MUC5AC 1 0.34 0.75 0 88.16
77 INT94542 Gene_expression of MT1G 1 0.17 1.12 0.08 88.08
78 INT134297 Positive_regulation of Gene_expression of Ptges2 22 0.41 13.12 4.97 87.92
79 INT198453 Negative_regulation of MUC5AC 12 0.58 12.96 1.38 87.80
80 INT94528 Gene_expression of MT1H 1 0.36 1.11 0.08 87.80
81 INT48324 Positive_regulation of ODZ1 2 0.45 3.93 0.1 87.68
82 INT94540 Gene_expression of MT1X 6 0.49 5.51 0.28 87.52
83 INT73593 Gene_expression of BAX 173 0.76 147.81 20.94 87.52
84 INT17574 Binding of CISH 23 0.31 4.3 0.93 87.36
85 INT199140 Binding of MT3 1 0.36 1.56 0.17 86.96
86 INT101820 Negative_regulation of KEAP1 20 0.58 18.79 0.19 86.44
87 INT197574 Positive_regulation of Negative_regulation of KEAP1 1 0.50 1.15 0 86.44
88 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 85.32
89 INT101831 Gene_expression of KEAP1 21 0.77 10.82 0.12 85.04
90 INT197560 Negative_regulation of Gene_expression of KEAP1 5 0.58 3.12 0 85.04
91 INT62681 Negative_regulation of LEP 93 0.59 66.97 15.77 84.84
92 INT177875 Positive_regulation of Positive_regulation of NFE2L2 18 0.66 9.4 0.4 84.80
93 INT94164 Phosphorylation of RB1 83 0.80 48.84 3.21 84.72
94 INT94169 Negative_regulation of Phosphorylation of RB1 16 0.41 8.87 1.57 84.72
95 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 84.32
96 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0 84.32
97 INT163280 Negative_regulation of Phosphorylation of CCND1 6 0.19 3.92 0.87 83.92
98 INT163289 Phosphorylation of CCND1 7 0.36 4.81 0.81 83.92
99 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 82.24
100 INT76531 Transcription of Trpv1 62 0.72 23.69 34.77 82.00
101 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 81.84
102 INT2137 Localization of Cea 27 0.70 19.22 6.14 81.84
103 INT281256 Positive_regulation of CCND2 1 0.20 1.42 0 81.60
104 INT57691 Regulation of Gene_expression of Ptger2 23 0.40 17.08 4.61 81.20
105 INT39565 Gene_expression of Ptger2 424 0.75 229.28 72.68 80.72
106 INT11159 Gene_expression of EGFR 698 0.78 548.93 25.69 79.64
107 INT11158 Positive_regulation of Gene_expression of EGFR 165 0.70 131.26 4.93 79.64
108 INT103683 Gene_expression of Muc2 18 0.73 12.47 2.43 79.24
109 INT109334 Regulation of SOD2 13 0.60 7.48 2.14 79.08
110 INT94531 Transcription of MT2A 2 0.56 1.52 0.07 78.00
111 INT94525 Transcription of MT1X 1 0.43 1.08 0.07 78.00
112 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 77.60
113 INT187781 Positive_regulation of Slc11a1 3 0.24 1.76 0 77.20
114 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 76.56
115 INT94532 Regulation of MT2A 5 0.36 4.25 0.98 75.84
116 INT94543 Binding of MT2A 5 0.29 0.96 0.36 75.84
117 INT94529 Binding of ALG1 2 0.17 0.96 0.21 75.12
118 INT94539 Regulation of ALG1 1 0.22 0.72 0.09 75.12
119 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 75.00
120 INT94533 Positive_regulation of MT1X 1 0.44 1.78 0.14 74.60
121 INT11807 Gene_expression of Il2 266 0.78 112 64.97 74.24
122 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 73.08
123 INT87406 Gene_expression of GSTP1 16 0.77 11.37 0.35 72.88
124 INT120761 Positive_regulation of GSTP1 3 0.50 3.4 0.19 72.88
125 INT95328 Gene_expression of Gstp1 11 0.61 8.59 0.48 72.32
126 INT94537 Gene_expression of Metallothionein isoform 1 1 0.11 1.29 0.14 72.32
127 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 70.92
128 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 69.16
129 INT103681 Negative_regulation of Gene_expression of Krt7 1 0.01 0.97 1.12 69.08
130 INT103682 Gene_expression of Krt7 2 0.17 3.17 1.11 69.08
131 INT94541 Positive_regulation of Gene_expression of MT1X 1 0.44 1.84 0.06 68.88
132 INT305348 Gene_expression of Peg3 2 0.25 2.36 0.31 66.72
133 INT86813 Gene_expression of Pla2g4a 26 0.75 42.31 10.07 66.40
134 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 66.24
135 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 66.24
136 INT199137 Negative_regulation of Gene_expression of MT3 1 0.43 1.49 0.14 66.16
137 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 65.72
138 INT250899 Gene_expression of Thbs2 17 0.75 4.97 0.13 65.68
139 INT305352 Gene_expression of HOXA11 1 0.23 1.22 0 65.68
140 INT184475 Protein_catabolism of Ptger2 5 0.30 1.85 0.57 64.96
141 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 64.88
142 INT11154 Binding of EGFR 149 0.48 96.23 6.29 63.76
143 INT15376 Positive_regulation of Gene_expression of ERBB2 215 0.70 168.54 5.23 63.76
144 INT178615 Binding of SOD2 12 0.48 6.93 1.51 63.60
145 INT1995 Gene_expression of ptd 2 0.58 1.98 0.16 62.88
146 INT109975 Positive_regulation of Kras 14 0.45 12.72 1.68 61.72
147 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 61.56
148 INT94535 Negative_regulation of Gene_expression of MT2A 1 0.34 1.7 0.07 60.40
149 INT8556 Positive_regulation of NQO1 12 0.70 5.11 1.78 60.16
150 INT59891 Positive_regulation of GSTK1 46 0.67 17.66 5.33 59.80
151 INT94530 Negative_regulation of Gene_expression of ALG1 1 0.20 0.55 0.07 59.68
152 INT82434 Positive_regulation of LEP 117 0.70 95.45 20.22 59.64
153 INT97443 Positive_regulation of Positive_regulation of LEP 13 0.50 11.91 2.65 59.64
154 INT221438 Gene_expression of Tis 2 0.34 1.51 0 59.24
155 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 59.16
156 INT304052 Binding of MSI1 8 0.05 12.19 0 58.48
157 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 58.16
158 INT16165 Regulation of DMD 114 0.60 35.13 3.64 58.12
159 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 58.12
160 INT94536 Negative_regulation of Gene_expression of metallothionein isoform 1 1 0.06 0.54 0.07 58.00
161 INT64201 Negative_regulation of Trpv1 203 0.59 79.18 119.75 57.00
162 INT111545 Phosphorylation of VEGFA 50 0.76 22.19 5.88 56.32
163 INT315145 Phosphorylation of Flt1 4 0.40 2.88 0.09 55.96
164 INT199135 Negative_regulation of Localization of MT3 1 0.43 0.81 0.06 55.44
165 INT199136 Localization of MT3 1 0.75 0.8 0.06 55.44
166 INT192298 Negative_regulation of MMP7 7 0.27 3.71 3.29 55.44
167 INT132760 Gene_expression of Pgr 47 0.66 28.17 2.85 55.04
168 INT9165 Negative_regulation of MSLN 7 0.37 2.08 0.2 54.72
169 INT237211 Negative_regulation of WFDC2 1 0.38 1.01 0 54.24
170 INT8545 Negative_regulation of MUC16 19 0.57 15.96 2.81 53.68
171 INT129756 Regulation of MUC5AC 7 0.34 6.45 0.7 53.68
172 INT113399 Positive_regulation of Pla2g4a 36 0.67 33.83 18.78 52.48
173 INT266931 Positive_regulation of Binding of EGFR 6 0.50 5.44 0 52.24
174 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 52.00
175 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24 52.00
176 INT101829 Positive_regulation of Localization of NFE2L2 9 0.67 3.61 0.38 51.68
177 INT89105 Gene_expression of Gapdh 27 0.75 4.32 1.15 51.64
178 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 51.20
179 INT101816 Localization of NFE2L2 17 0.77 6.91 1.69 50.96
180 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 50.92
181 INT185916 Gene_expression of NAF1 16 0.65 4.27 0.53 49.96
182 INT216267 Binding of IARS 4 0.32 5.34 0.37 48.88
183 INT134951 Gene_expression of NQO1 14 0.78 7.87 0.61 47.92
184 INT3845 Gene_expression of GSR 79 0.76 44.69 11.19 47.56
185 INT259116 Transcription of BRCA1 3 0.44 3.77 0 46.80
186 INT111605 Positive_regulation of CDH1 12 0.50 7.95 1.15 45.84
187 INT157765 Negative_regulation of CDH1 32 0.53 35.72 1.15 45.84
188 INT101818 Gene_expression of NFE2L2 48 0.78 23.8 0.66 44.36
189 INT259108 Negative_regulation of LMO4 1 0.59 0.74 0 43.04
190 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 41.32
191 INT91370 Phosphorylation of STAT3 123 0.82 49.25 8.42 40.60
192 INT108336 Phosphorylation of EPHB2 41 0.80 22.25 8.21 40.60
193 INT186064 Phosphorylation of STAT1 19 0.59 7.14 1.48 40.60
194 INT162462 Protein_catabolism of TP53 8 0.86 7.89 1.41 39.76
195 INT49214 Gene_expression of Cd4 269 0.78 154.22 34.05 39.24
196 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 39.24
197 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 38.76
198 INT12124 Gene_expression of MAPK1 141 0.75 82.4 25.58 38.76
199 INT205888 Positive_regulation of Gene_expression of Pla2g4a 7 0.67 8 0.9 37.44
200 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 36.92
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