D:Carney Complex

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pChart

Disease Term
Synonyms Carney Complex Type 1, Carney Complex Type 2, CARNEY COMPLEX TYPE I, Carney Complex Type Ii, CARNEY MYXOMA ENDOCRINE COMPLEX, Carney Syndrome, Complex Carney, Complex Carney Myxoma Endocrine, LAMB SYNDROME, LAMB SYNDROMES, Myxoma Endocrine Complex Carney
Documents 16
Hot Single Events 16
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Carney Complex. They are ordered first by their relevance to Carney Complex and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT308432 Binding of PDE4A and Aip 1 0.05 3.1 0.05 47.40
2 INT308425 Binding of Pde2a and Aip 1 0.04 1.37 0 47.40
3 INT339794 Sstr2 Positive_regulation of Gene_expression of Sstr5 1 0.08 0.25 0.64 5.00
4 INT239087 Binding of SST and Negative_regulation of Localization of GH1 1 0.19 0.36 0.24 5.00
5 INT289878 Binding of MMD and SEPN1 1 0.16 1.27 0 5.00
6 INT308426 Binding of Pde4a and Aip 1 0.02 0.89 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Carney Complex. They are ordered first by their pain relevance and then by number of times they were reported in Carney Complex. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT115423 Gene_expression of Men1 4 0.47 14.08 0.64 100.00
2 INT327715 Binding of CNC 1 0.07 1.21 0.07 100.00
3 INT308431 Gene_expression of CNC 1 0.01 2.84 0.18 100.00
4 INT327714 Localization of CNC 1 0.10 0.79 0.09 100.00
5 INT15347 Positive_regulation of Localization of Pomc 81 0.70 28.1 31.01 98.32
6 INT1438 Localization of Pomc 360 0.81 101.26 116.47 97.96
7 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 97.44
8 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64 97.44
9 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 97.04
10 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38 97.04
11 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 96.88
12 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 95.52
13 INT695 Binding of POMC 304 0.48 56.66 126.85 95.40
14 INT1893 Localization of Gh 1041 0.79 340.23 256.58 93.08
15 INT114091 Negative_regulation of Aip 6 0.48 4.16 1.3 87.44
16 INT252 Localization of GH1 529 0.80 227.4 122.05 82.76
17 INT249 Localization of GHRH 215 0.80 78.02 51.87 78.56
18 INT443 Localization of POMC 1020 0.81 284.52 443.17 76.48
19 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 65.04
20 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 65.04
21 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 64.60
22 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 60.72
23 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 57.28
24 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 56.88
25 INT180250 Positive_regulation of GLUL 23 0.29 7.57 3.23 53.92
26 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 39.84
27 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 39.20
28 INT148671 Gene_expression of Aip 26 0.63 24.32 3.91 36.84
29 INT70021 Localization of BCL2 23 0.74 21.6 1.09 33.32
30 INT161382 Localization of KRT20 25 0.61 12.97 2.13 32.80
31 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 28.36
32 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 25.00
33 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 24.72
34 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 17.84
35 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 5.00
36 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
37 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
38 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 5.00
39 INT1530 Regulation of Gh 382 0.61 115.96 112.47 5.00
40 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
41 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 5.00
42 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 5.00
43 INT462 Regulation of Pomc 157 0.62 41.67 67.27 5.00
44 INT253 Regulation of PRL 184 0.62 47.27 65.79 5.00
45 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 5.00
46 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
47 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 5.00
48 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
49 INT5118 Regulation of SST 97 0.62 34.35 51.74 5.00
50 INT1199 Positive_regulation of INS 579 0.70 399.64 50.43 5.00
51 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 5.00
52 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 5.00
53 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
54 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 5.00
55 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 5.00
56 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 5.00
57 INT691 Binding of SST 67 0.48 24.66 32.67 5.00
58 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 5.00
59 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 5.00
60 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 5.00
61 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 5.00
62 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 5.00
63 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
64 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 5.00
65 INT11628 Regulation of Localization of Pomc 44 0.61 10.46 18.66 5.00
66 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 5.00
67 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 5.00
68 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8 5.00
69 INT27266 Regulation of Gene_expression of Pomc 41 0.62 6.74 14.59 5.00
70 INT8210 Positive_regulation of Gene_expression of INS 188 0.68 146.57 12.83 5.00
71 INT35467 Gene_expression of DIO2 37 0.65 9.56 12.61 5.00
72 INT76428 Gene_expression of Sstr2 24 0.76 6.09 12.32 5.00
73 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 5.00
74 INT1436 Negative_regulation of Localization of Pomc 41 0.58 10.85 11.26 5.00
75 INT987 Localization of TRH 37 0.78 10.53 11.1 5.00
76 INT10009 Positive_regulation of TRH 31 0.67 8.94 11.03 5.00
77 INT91774 Gene_expression of Nr3c1 27 0.78 16.14 10.7 5.00
78 INT31780 Binding of DIO2 17 0.36 10.07 10 5.00
79 INT8740 Localization of Gcg 65 0.78 19 9.81 5.00
80 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 5.00
81 INT26751 Regulation of Nr3c1 13 0.61 6.58 8.65 5.00
82 INT34777 Localization of IGF1 82 0.80 42.68 8.62 5.00
83 INT156827 Localization of MRI1 25 0.65 16.06 8.33 5.00
84 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 5.00
85 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 5.00
86 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 5.00
87 INT110599 Gene_expression of Bglap 49 0.74 41.23 6.97 5.00
88 INT28861 Binding of Gh 61 0.46 25.61 6.38 5.00
89 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
90 INT121801 Binding of Aip 18 0.36 24.1 5.26 5.00
91 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 5.00
92 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 5.00
93 INT14557 Negative_regulation of Igf1 96 0.59 54.83 4.45 5.00
94 INT8744 Regulation of Localization of Gcg 14 0.60 2.06 4.3 5.00
95 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 5.00
96 INT131165 Positive_regulation of Gene_expression of Nr3c1 8 0.70 7.18 3.44 5.00
97 INT155983 Gene_expression of Cyp11a1 7 0.58 2.6 3.38 5.00
98 INT48726 Gene_expression of IGFBP1 27 0.67 9.45 3.36 5.00
99 INT4488 Gene_expression of TSHB 10 0.41 4.69 3.09 5.00
100 INT123802 Localization of Sstr2 8 0.80 3.54 3.01 5.00
101 INT16130 Binding of IGF1 67 0.48 27.43 2.95 5.00
102 INT173236 Binding of Sstr2 8 0.25 1.64 2.41 5.00
103 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 5.00
104 INT149451 Gene_expression of Sstr5 3 0.39 1.5 2.24 5.00
105 INT239093 Gene_expression of PTTG1 84 0.65 83.94 1.87 5.00
106 INT57018 Gene_expression of GANAB 9 0.08 3.76 1.79 5.00
107 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 5.00
108 INT48616 Positive_regulation of IGFBP1 14 0.43 5.62 1.56 5.00
109 INT102064 Binding of Sstr5 3 0.20 0.86 1.55 5.00
110 INT135959 Negative_regulation of Gene_expression of Igf1 37 0.56 21.16 1.41 5.00
111 INT184303 Positive_regulation of Bglap 16 0.66 8.66 1.25 5.00
112 INT45079 Binding of Ahr 21 0.44 10.07 1 5.00
113 INT192300 Positive_regulation of Gene_expression of IGFBP1 6 0.60 2.85 0.81 5.00
114 INT316547 Binding of Sst1 2 0.10 0.84 0.74 5.00
115 INT278006 Binding of Sstr3 2 0.33 1.07 0.71 5.00
116 INT158836 Positive_regulation of Localization of TRH 7 0.49 2.61 0.67 5.00
117 INT339791 Negative_regulation of Gene_expression of Sstr2 1 0.14 0.25 0.63 5.00
118 INT178752 Binding of IGFBP1 8 0.15 4.58 0.61 5.00
119 INT335719 Positive_regulation of Gene_expression of DIO2 3 0.23 0.59 0.61 5.00
120 INT154613 Regulation of Aip 5 0.21 3.86 0.55 5.00
121 INT55047 Gene_expression of GNRHR 8 0.78 5.2 0.53 5.00
122 INT155904 Localization of MMD 9 0.32 3.77 0.49 5.00
123 INT211968 Localization of Best1 11 0.40 9.33 0.38 5.00
124 INT173238 Negative_regulation of Sstr2 2 0.16 0.68 0.34 5.00
125 INT257213 Binding of PDE4A 5 0.36 1.69 0.3 5.00
126 INT12531 Localization of GANAB 3 0.09 2.79 0.26 5.00
127 INT325236 Positive_regulation of Localization of Sstr2 2 0.25 0.81 0.22 5.00
128 INT263128 Negative_regulation of Binding of PDE4A 3 0.22 1.33 0.18 5.00
129 INT172368 Negative_regulation of Binding of IGF1 3 0.42 1.57 0.18 5.00
130 INT289892 Gene_expression of SEPN1 3 0.42 1.17 0.13 5.00
131 INT239095 Negative_regulation of PTTG1 2 0.32 8.24 0.09 5.00
132 INT239094 Negative_regulation of Binding of GH1 2 0.34 1.61 0.06 5.00
133 INT239092 Positive_regulation of Binding of IGFBP1 1 0.04 0.6 0.04 5.00
134 INT308430 Negative_regulation of PRKAR1A 1 0.11 0.83 0.04 5.00
135 INT231433 Positive_regulation of Binding of IGFBP3 2 0.34 0.6 0.04 5.00
136 INT308415 Negative_regulation of Transcription of Aip 1 0.48 0.82 0.03 5.00
137 INT308414 Negative_regulation of Gene_expression of Aip 1 0.48 0.82 0.03 5.00
138 INT289876 Localization of Eng 3 0.44 0.59 0 5.00
139 INT289891 Localization of SEPN1 1 0.42 0.88 0 5.00
140 INT308416 Regulation of Gene_expression of Aip 1 0.37 0.77 0 5.00
141 INT308427 Positive_regulation of MTUS1 1 0.00 1.02 0 5.00
142 INT289877 Binding of Lama2 1 0.36 0.48 0 5.00
143 INT308417 Transcription of Aip 1 0.59 0.82 0 5.00
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