D:Compartment Syndromes

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Disease Term
Synonyms Compartment Syndrome, Syndrome Compartment, SYNDROMES COMPARTMENT
Documents 710
Hot Single Events 47
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Compartment Syndromes. They are ordered first by their relevance to Compartment Syndromes and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT120880 Mb Positive_regulation of Ldha 1 0.07 0.55 0 81.08
2 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 70.12
3 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 6.04
4 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
5 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
6 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
7 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
8 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 5.00
9 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 5.00
10 INT316101 Binding of HIST1H4PS1 and ANGPTL5 1 0.01 0.28 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Compartment Syndromes. They are ordered first by their pain relevance and then by number of times they were reported in Compartment Syndromes. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT102698 Binding of ACCS 54 0.42 66.73 9.06 100.00
2 INT86184 Negative_regulation of Acsl1 10 0.34 20.45 2.23 100.00
3 INT75869 Gene_expression of Acsl1 24 0.45 27.76 3.66 100.00
4 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 100.00
5 INT147607 Binding of TERT 16 0.48 12.36 1.31 100.00
6 INT110110 Gene_expression of ACCS 85 0.58 75.88 10.2 100.00
7 INT55619 Binding of Acsl1 8 0.31 9.91 1.22 100.00
8 INT152982 Negative_regulation of ACCS 14 0.37 9.63 1.3 100.00
9 INT141132 Regulation of ACCS 14 0.29 13.92 1.89 100.00
10 INT220329 Positive_regulation of IAH1 3 0.20 4.37 0 99.80
11 INT324519 Binding of IAH1 2 0.13 1.43 0 99.80
12 INT220331 Negative_regulation of IAH1 2 0.19 1.52 0.07 99.80
13 INT37170 Binding of APCS 6 0.36 4.79 0.97 99.72
14 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 99.70
15 INT250751 Regulation of Regulation of IAPP 1 0.04 0.9 0 99.48
16 INT18845 Regulation of IAPP 11 0.60 9 1.81 99.20
17 INT7134 Localization of KNG1 127 0.79 65.73 67.97 98.56
18 INT18844 Binding of IAPP 11 0.36 11.01 1.45 98.36
19 INT28872 Positive_regulation of CSRP1 49 0.70 47.23 11.7 97.76
20 INT164196 Binding of LRP1 5 0.47 2.59 0.53 97.16
21 INT2442 Localization of Mb 38 0.80 24.74 6.33 96.12
22 INT5008 Localization of Calca 204 0.81 80.35 125.16 95.60
23 INT103251 Negative_regulation of Localization of Calca 13 0.43 9.36 8.86 95.60
24 INT9908 Negative_regulation of IAPP 29 0.57 19.37 2.12 94.36
25 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 93.76
26 INT2919 Negative_regulation of F8 47 0.59 23.48 5.1 93.68
27 INT222293 Positive_regulation of Iah1 1 0.02 1.63 0.26 91.88
28 INT122051 Negative_regulation of ROM1 17 0.48 9.11 3.38 90.00
29 INT103327 Gene_expression of F8 45 0.71 32.5 2.12 89.08
30 INT19177 Negative_regulation of GRHPR 19 0.53 12.65 2.71 89.00
31 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 88.92
32 INT251830 Binding of TYMP 2 0.13 4.36 0.37 88.80
33 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 86.36
34 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 86.08
35 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 85.96
36 INT60749 Localization of IAPP 17 0.78 12.57 1.69 85.60
37 INT894 Binding of Avp 84 0.48 29.16 29.63 85.32
38 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 84.92
39 INT2792 Gene_expression of Mb 91 0.76 41.56 10.25 84.20
40 INT34244 Gene_expression of Magt1 3 0.54 1.19 0.76 83.32
41 INT6852 Localization of TNF 883 0.81 705.95 270.84 82.96
42 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 82.28
43 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 81.20
44 INT18391 Positive_regulation of GYPA 41 0.40 16.47 8.69 81.04
45 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 80.92
46 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 80.64
47 INT98096 Positive_regulation of CHKA 14 0.42 12.23 1.61 80.44
48 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 79.56
49 INT58571 Positive_regulation of ALDOB 6 0.49 5.63 0.53 79.52
50 INT148400 Localization of Sfn 1 0.74 0.76 0.13 79.24
51 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 79.12
52 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 76.24
53 INT336942 Negative_regulation of Cfh 2 0.18 1.8 0.08 75.40
54 INT15229 Positive_regulation of CNDP1 21 0.69 15.86 4.06 75.00
55 INT28894 Positive_regulation of PLK2 3 0.50 3.77 0.69 75.00
56 INT373 Regulation of Ldha 37 0.61 17.86 11.41 74.80
57 INT23420 Positive_regulation of Spn 8 0.49 4.81 0.69 74.24
58 INT107987 Gene_expression of MRC1 27 0.75 36.94 1.99 73.64
59 INT231888 Negative_regulation of Positive_regulation of IAPP 2 0.42 2.43 0.23 73.04
60 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 70.84
61 INT10870 Regulation of IgG 67 0.59 43.27 12.74 70.84
62 INT48909 Localization of DLD 9 0.63 3.37 0.75 70.16
63 INT11367 Localization of MB 9 0.78 9.34 1.24 68.96
64 INT211375 Regulation of Gene_expression of TYMP 2 0.43 2.44 0.22 66.80
65 INT105021 Binding of GOPC 187 0.40 60.39 20.38 66.32
66 INT120722 Gene_expression of TYMP 35 0.75 19.26 1.31 64.84
67 INT134889 Negative_regulation of TNFRSF11A 9 0.42 12.65 1.76 63.68
68 INT138556 Positive_regulation of TYMP 23 0.58 12.9 0.28 61.60
69 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 54.76
70 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45 53.64
71 INT88466 Regulation of Gene_expression of Ldha 5 0.33 4.07 0.97 53.64
72 INT5409 Negative_regulation of G6pd 33 0.57 29.21 7.64 52.64
73 INT37835 Negative_regulation of CPP 61 0.51 31.34 18.57 51.36
74 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 50.00
75 INT105670 Gene_expression of AAVS1 131 0.75 49.24 12.95 48.00
76 INT29835 Regulation of Gene_expression of TBXA2R 7 0.50 3.92 2.57 48.00
77 INT18830 Localization of TBXA2R 25 0.81 7.14 9.28 40.72
78 INT22276 Gene_expression of TBXA2R 65 0.77 23.22 14.21 40.00
79 INT179729 Gene_expression of MBOAT7 2 0.17 1.05 0.07 26.96
80 INT354726 Binding of Tymp 1 0.30 1.08 0.23 22.80
81 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 16.88
82 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 14.08
83 INT27798 Gene_expression of Ntrk2 111 0.78 56.08 42.68 7.44
84 INT76660 Gene_expression of Trpv1 691 0.78 329.46 386.42 5.00
85 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
86 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
87 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
88 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
89 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
90 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
91 INT812 Localization of INS 1026 0.81 515.6 145.31 5.00
92 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
93 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
94 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 5.00
95 INT65731 Gene_expression of Cnr1 234 0.78 63.82 109.34 5.00
96 INT5940 Negative_regulation of Avp 236 0.59 67.86 101.2 5.00
97 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 5.00
98 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 5.00
99 INT19771 Positive_regulation of PAG1 69 0.61 75.61 76.88 5.00
100 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 5.00
101 INT98621 Regulation of Trpv1 121 0.62 79.24 75.23 5.00
102 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 5.00
103 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 5.00
104 INT65733 Positive_regulation of Cnr1 125 0.70 40.27 67.33 5.00
105 INT65730 Gene_expression of Cnr2 129 0.78 60.15 63.1 5.00
106 INT46 Localization of Ren 233 0.81 46.15 62.44 5.00
107 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 5.00
108 INT1456 Regulation of Oprl1 61 0.62 19.5 52.87 5.00
109 INT50334 Negative_regulation of Cnr1 84 0.58 30.86 51.75 5.00
110 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21 5.00
111 INT98498 Binding of Trpv1 75 0.48 33.67 44.4 5.00
112 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
113 INT3253 Negative_regulation of Localization of INS 205 0.59 130.39 36.61 5.00
114 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 5.00
115 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 5.00
116 INT66005 Regulation of Cnr1 47 0.61 19.21 34.52 5.00
117 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 5.00
118 INT34465 Regulation of Oprd1 34 0.45 7.14 34.29 5.00
119 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 5.00
120 INT5966 Localization of Il1a 50 0.78 22.91 26.54 5.00
121 INT125190 Regulation of Gene_expression of Trpv1 38 0.62 32.57 23.2 5.00
122 INT74286 Regulation of Il10 42 0.44 28.06 19.44 5.00
123 INT101578 Regulation of Cnr2 26 0.62 16.7 19.12 5.00
124 INT120446 Positive_regulation of Cnr2 32 0.70 16.3 18.91 5.00
125 INT66004 Binding of Cnr2 35 0.48 12.82 18.63 5.00
126 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42 5.00
127 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
128 INT3364 Binding of SGCG 87 0.47 31.93 17.24 5.00
129 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 5.00
130 INT170335 Gene_expression of INCENP 176 0.54 91.62 15.31 5.00
131 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 5.00
132 INT75540 Positive_regulation of TH1L 62 0.67 43.45 15.02 5.00
133 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 5.00
134 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 5.00
135 INT127022 Gene_expression of Lts1 43 0.23 28.29 12.64 5.00
136 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56 5.00
137 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 5.00
138 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 5.00
139 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 5.00
140 INT424 Positive_regulation of TSPO 34 0.61 15.04 10.02 5.00
141 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 5.00
142 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 5.00
143 INT6499 Localization of Ntrk2 44 0.79 11.78 8.75 5.00
144 INT61264 Regulation of Jun 36 0.61 18.42 8.71 5.00
145 INT44550 Positive_regulation of Gene_expression of AVP 38 0.70 22.27 8.62 5.00
146 INT73234 Positive_regulation of Lbp 13 0.69 12.55 8.57 5.00
147 INT39170 Gene_expression of TSPO 76 0.78 24.11 8.05 5.00
148 INT6335 Binding of TSPO 39 0.44 10.88 7.66 5.00
149 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 5.00
150 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 5.00
151 INT168399 Localization of Cnr2 12 0.81 4.37 6.77 5.00
152 INT43721 Gene_expression of Vegfa 49 0.77 36.18 6.63 5.00
153 INT81586 Negative_regulation of Casp1 11 0.57 6.55 6.45 5.00
154 INT9951 Gene_expression of ANGPTL5 45 0.53 37.2 6.44 5.00
155 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 5.00
156 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 5.00
157 INT134585 Negative_regulation of Cnr2 10 0.43 3.98 6.16 5.00
158 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 5.00
159 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84 5.00
160 INT59555 Binding of RYR1 39 0.42 8.65 4.92 5.00
161 INT16214 Localization of F13A1 36 0.74 21.8 4.87 5.00
162 INT37661 Negative_regulation of SERPINC1 48 0.59 38.6 4.77 5.00
163 INT189842 Negative_regulation of Gene_expression of Cnr2 8 0.59 4.21 4.67 5.00
164 INT27316 Negative_regulation of TPO 7 0.38 7.26 4.42 5.00
165 INT188588 Localization of Mthfd1 20 0.49 9.19 4.37 5.00
166 INT162249 Gene_expression of Hist1h2aa 8 0.12 6.46 4.35 5.00
167 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93 5.00
168 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 5.00
169 INT149259 Gene_expression of RCT 38 0.67 15.73 3.87 5.00
170 INT84427 Positive_regulation of Gene_expression of TSPO 15 0.64 5.05 3.58 5.00
171 INT11107 Binding of Lbp 12 0.42 4.42 3.41 5.00
172 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 5.00
173 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
174 INT61087 Positive_regulation of Gene_expression of Il2ra 12 0.35 9.1 3.25 5.00
175 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 5.00
176 INT9110 Binding of PAH 32 0.41 42.1 3.1 5.00
177 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
178 INT10189 Negative_regulation of Gene_expression of Il2ra 8 0.32 8.05 2.91 5.00
179 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 5.00
180 INT203154 Positive_regulation of Gene_expression of Lts1 6 0.17 3.68 2.67 5.00
181 INT222289 Localization of Il18 4 0.30 3.24 2.58 5.00
182 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53 5.00
183 INT200217 Localization of PAH 10 0.36 15.51 2.46 5.00
184 INT5968 Positive_regulation of Localization of Il1a 4 0.65 1.36 2.42 5.00
185 INT46088 Localization of F3 15 0.37 13.7 2.23 5.00
186 INT43612 Regulation of SERPINB1 12 0.11 3.26 2.21 5.00
187 INT11580 Binding of Cebpz 8 0.40 7.16 2.19 5.00
188 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15 5.00
189 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 5.00
190 INT9840 Positive_regulation of F7 17 0.57 17.83 2.08 5.00
191 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 5.00
192 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02 5.00
193 INT122195 Regulation of Localization of VEGFA 13 0.57 10.61 1.92 5.00
194 INT40857 Positive_regulation of MAOA 6 0.49 2.51 1.71 5.00
195 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
196 INT11713 Localization of RYR1 22 0.76 10.42 1.64 5.00
197 INT21852 Regulation of Gene_expression of Ap3d1 2 0.18 1.34 1.54 5.00
198 INT161276 Regulation of NHS 7 0.38 1.43 1.4 5.00
199 INT351303 Regulation of Binding of Cnr2 1 0.10 0.66 1.39 5.00
200 INT351302 Regulation of Regulation of Cnr1 1 0.10 0.78 1.39 5.00
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