D:Constipation

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pChart

Disease Term
Synonyms ACUTE CONSTIPATION, Calcium Polycarbophil, Catharsis, Cathartic Colon, Chronic Constipation, Colon Stasis, Colonic Inertia, Dyschezia, Faecal Impaction, Fecal Impaction, Inactive Colon
Documents 4087
Hot Single Events 200
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Constipation. They are ordered first by their relevance to Constipation and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT175560 Binding of GPER and GHRL 1 0.01 1.14 0.03 100.00
2 INT334928 Binding of pr and Aes 1 0.00 1.49 3.38 96.00
3 INT351380 Ngf Regulation of TPM1 1 0.44 2.17 2.11 95.92
4 INT81267 Negative_regulation of Binding of MLN and NCOR2 1 0.02 0.28 0.56 95.84
5 INT118239 Binding of CCKAR and CYP2B6 1 0.32 0.19 0.29 95.60
6 INT81265 Binding of MLN and NCOR2 1 0.02 0.23 0.51 95.36
7 INT118136 Binding of HTR1A and HTR2A 1 0.36 0.77 0.45 92.56
8 INT58249 CCK Positive_regulation of Regulation of GAST 1 0.48 0.86 0.5 91.56
9 INT326605 Binding of HTR1A and KCNH2 1 0.00 0.45 0.14 90.80
10 INT20259 Sct Positive_regulation of Gast 1 0.01 0.86 0.09 90.40
11 INT262367 Tcas1 Positive_regulation of Localization of Adh4 1 0.01 1.91 1.01 90.20
12 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03 89.52
13 INT144107 Binding of SLC6A2 and SLC6A4 1 0.00 0.18 0.62 89.52
14 INT278015 Gh Regulation of Ins1 1 0.10 1.47 0.27 83.96
15 INT317259 Pyy Positive_regulation of Ins1 1 0.02 0.33 0.12 83.56
16 INT278018 Gh Negative_regulation of Phosphorylation of Ins1 1 0.13 1.5 0.29 81.04
17 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 78.08
18 INT299282 PTPN3 Negative_regulation of Positive_regulation of RPTOR 1 0.07 0.48 0.67 74.00
19 INT299263 PTPN3 Negative_regulation of VEGFA Positive_regulation of SRC 1 0.03 0.35 0.57 74.00
20 INT206704 Negative_regulation of Binding of KDR and VEGFA 4 0.39 5.18 0.3 73.44
21 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 73.00
22 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2 72.20
23 INT299286 VEGFA Positive_regulation of PI3 1 0.16 0.46 0.6 72.20
24 INT106837 Binding of Oprm1 and Arrb2 3 0.32 0.83 3.01 69.44
25 INT139745 Positive_regulation of Binding of Oprm1 and Arrb2 1 0.28 0.14 0.81 69.44
26 INT278012 Gh Positive_regulation of Gene_expression of Ins1 1 0.11 1.24 0.26 67.44
27 INT278077 Binding of BPHL and AURKC 1 0.16 4.29 0.69 67.04
28 INT278016 Gh Positive_regulation of Localization of Ins1 1 0.16 1.22 0.26 64.96
29 INT224308 INSRR Regulation of VEGFA 1 0.00 1.42 0.16 64.48
30 INT279284 TXK Regulation of KDR 3 0.05 2.22 0.04 64.48
31 INT193193 Binding of CRS and RAPH1 1 0.12 1.47 0 62.00
32 INT299725 AFP Positive_regulation of Positive_regulation of ACPP 1 0.00 0.78 0.17 56.36
33 INT247030 Prkaca Regulation of Positive_regulation of Cftr 1 0.05 0 0 50.00
34 INT247031 Npr1 Positive_regulation of Prkaca 1 0.00 0 0 50.00
35 INT297614 ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.56 0 48.56
36 INT297613 Negative_regulation of ZNF275 Positive_regulation of Gene_expression of TSC1 1 0.00 1.66 0 48.56
37 INT325295 Binding of SGCA and C14orf166 1 0.04 0.54 0.08 46.64
38 INT258858 CTSB Positive_regulation of Gene_expression of IL8 1 0.00 0.64 0.28 41.92
39 INT204159 Slc11a2 Regulation of Gene_expression of HAMP 1 0.11 1.08 0.14 35.32
40 INT191984 Ide Positive_regulation of Nppc 1 0.04 0.13 0 34.80
41 INT122710 GUCA2A Positive_regulation of RTCA 1 0.03 0.16 0.05 25.00
42 INT122713 Guca2b Positive_regulation of RTCA 1 0.03 0.16 0.05 25.00
43 INT175561 NAA50 Negative_regulation of PRELID1 1 0.00 0.83 0.1 22.56
44 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 21.28
45 INT353646 Binding of NPL and H58 1 0.01 0.26 0 20.28
46 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0 18.80
47 INT354097 Timp1 Negative_regulation of Localization of NFKB2 1 0.04 0.94 0 17.28
48 INT354096 Timp1 Negative_regulation of Positive_regulation of NFKB2 1 0.04 0.94 0 17.28
49 INT299946 Binding of Tlr4 and Synj2bp 1 0.00 0.28 0 9.88
50 INT77646 Binding of Ngf and Ntrk1 23 0.40 7.85 9.26 5.00
51 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
52 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 5.00
53 INT88279 Ngf Positive_regulation of Ntrk1 5 0.76 3.06 5.23 5.00
54 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 5.00
55 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
56 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
57 INT275850 Binding of NDUFAB1 and SNCA 1 0.00 3.78 3.16 5.00
58 INT220062 Binding of NGF and TNFRSF1B 1 0.10 2.21 2.81 5.00
59 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 5.00
60 INT220061 Binding of TRPV1 and TRPA1 1 0.15 1.7 2.69 5.00
61 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
62 INT103548 Binding of TRPV1 and TRPV3 3 0.37 1.82 2.28 5.00
63 INT97208 Binding of Gabrg1 and Gabbr1 2 0.07 0.31 1.94 5.00
64 INT104855 Prkaca Regulation of TRPV1 3 0.06 1.52 1.92 5.00
65 INT113550 Binding of FN1 and VTN 6 0.30 5.24 1.91 5.00
66 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 5.00
67 INT275851 PES1 Negative_regulation of CP 1 0.01 1.96 1.83 5.00
68 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
69 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
70 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
71 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
72 INT315180 Gene_expression of Mors1 Positive_regulation of Gene_expression of Oprm1 1 0.03 0.48 1.64 5.00
73 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
74 INT315181 Gene_expression of Mors1 Positive_regulation of Oprm1 1 0.03 0.48 1.64 5.00
75 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
76 INT220058 NGF Positive_regulation of Gene_expression of BDNF 1 0.12 1.31 1.48 5.00
77 INT220059 NGF Positive_regulation of Positive_regulation of BDNF 1 0.11 1.31 1.48 5.00
78 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
79 INT299311 Binding of RPTOR and RICTOR 1 0.38 0.21 1.4 5.00
80 INT220060 Negative_regulation of Binding of NGF and NTRK1 1 0.08 1.11 1.39 5.00
81 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
82 INT299281 Binding of RPTOR and MAPKAP1 1 0.23 0.21 1.3 5.00
83 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29 5.00
84 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26 5.00
85 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25 5.00
86 INT351379 Ngf Positive_regulation of Binding of Ngf and Ntrk1 1 0.38 0.63 1.21 5.00
87 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18 5.00
88 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18 5.00
89 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18 5.00
90 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18 5.00
91 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 5.00
92 INT290667 Il6 Positive_regulation of Stat3 3 0.69 2.42 1.15 5.00
93 INT221386 Tlr4 Positive_regulation of Gene_expression of IL8 6 0.14 3.53 0.9 5.00
94 INT301079 Binding of GNAT1 and INPP5E 1 0.00 0.59 0.89 5.00
95 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
96 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86 5.00
97 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86 5.00
98 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86 5.00
99 INT199491 Il6 Positive_regulation of Positive_regulation of Il6 1 0.00 0.81 0.86 5.00
100 INT199500 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.85 5.00
101 INT220056 Binding of NTF3 and NTRK1 1 0.07 1.12 0.78 5.00
102 INT220063 Binding of NTF3 and NTRK2 1 0.09 1.13 0.78 5.00
103 INT199495 Il4 Positive_regulation of Positive_regulation of Oprm1 1 0.00 0.98 0.78 5.00
104 INT199476 Il4 Positive_regulation of Transcription of Stat6 1 0.01 0.97 0.77 5.00
105 INT220057 Binding of NTS and TNFRSF1B 1 0.08 1.23 0.76 5.00
106 INT315185 Binding of CNOT1 and Tg(CAG-EGFP)D4Nagy 1 0.04 0.16 0.74 5.00
107 INT315182 Binding of Tg(CAG-EGFP)D4Nagy and Mors1 1 0.01 0.16 0.74 5.00
108 INT199488 Il4 Positive_regulation of Transcription of Oprm1 1 0.01 0.84 0.73 5.00
109 INT313778 Gene_expression of Crhq1 Negative_regulation of Localization of Crh 1 0.05 0.66 0.71 5.00
110 INT351374 Mir470 Negative_regulation of Ntrk3 1 0.00 1.55 0.7 5.00
111 INT351375 Mir470 Negative_regulation of Ntrk2 1 0.01 1.54 0.7 5.00
112 INT171901 Binding of TNF and Il1 2 0.18 1.07 0.7 5.00
113 INT351376 Mir470 Negative_regulation of Ntrk1 1 0.01 1.54 0.7 5.00
114 INT199489 Stat6 Positive_regulation of Oprm1 1 0.02 0.85 0.68 5.00
115 INT261517 Binding of HTR2A and USH1C 1 0.01 0 0.66 5.00
116 INT270762 IL1B Positive_regulation of IL1B Negative_regulation of IKBKB 1 0.02 1.13 0.66 5.00
117 INT270763 IL1B Negative_regulation of IKBKB 1 0.04 1.13 0.66 5.00
118 INT351276 CYP2D6 Regulation of CYP1A2 1 0.12 0 0.63 5.00
119 INT330984 Negative_regulation of CYP2D6 Positive_regulation of Localization of CYP1A2 1 0.46 0 0.62 5.00
120 INT315334 Binding of CYP3A4 and CDIPT 3 0.04 0.85 0.59 5.00
121 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 5.00
122 INT352270 Tnf Positive_regulation of GZMA 1 0.13 2.43 0.55 5.00
123 INT352268 Tnf Positive_regulation of Arl6ip6 1 0.02 2.42 0.54 5.00
124 INT290671 Binding of Socs3 and Stat3 2 0.23 1.59 0.45 5.00
125 INT275849 PES1 Positive_regulation of Gene_expression of TNFAIP1 1 0.01 1.28 0.42 5.00
126 INT290821 CRX Positive_regulation of Cort 1 0.14 0.51 0.41 5.00
127 INT326303 Binding of CRP and FKBP4 1 0.15 1.22 0.41 5.00
128 INT356199 GOPC Positive_regulation of Acot7 1 0.04 0.33 0.4 5.00
129 INT296945 ADIPOQ Negative_regulation of TNF 1 0.03 1.13 0.4 5.00
130 INT188336 IL6 Positive_regulation of Localization of POMC 1 0.01 0.83 0.4 5.00
131 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
132 INT310697 Tlr4 Positive_regulation of Gene_expression of Ptger2 2 0.03 1.34 0.38 5.00
133 INT350814 Negative_regulation of TNF Positive_regulation of Gene_expression of Cpox 1 0.06 1.33 0.37 5.00
134 INT229292 FXR1 Regulation of Gene_expression of FGF19 1 0.08 1.14 0.37 5.00
135 INT350816 TNF Positive_regulation of Gene_expression of Cpox 1 0.05 1.33 0.37 5.00
136 INT299288 AKT1 Positive_regulation of RPTOR 1 0.34 0.05 0.36 5.00
137 INT353128 Negative_regulation of Binding of TAC1 and B3GAT1 1 0.29 1.95 0.33 5.00
138 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
139 INT299307 AKT1 Positive_regulation of Positive_regulation of AKT1S1 1 0.10 0 0.3 5.00
140 INT299289 AKT1 Positive_regulation of Positive_regulation of TSC2 1 0.17 0 0.3 5.00
141 INT310696 Tlr4 Positive_regulation of Positive_regulation of Cftr 1 0.16 0.74 0.28 5.00
142 INT229332 BAS Negative_regulation of Pck1 1 0.01 0.2 0.28 5.00
143 INT185092 CRP Positive_regulation of ESR1 1 0.06 2.83 0.28 5.00
144 INT350813 Binding of Apc and Crp 1 0.18 1.12 0.27 5.00
145 INT191718 Binding of FLT1 and VEGFA 35 0.50 12.18 0.27 5.00
146 INT323926 MRM1 Positive_regulation of MRI1 1 0.04 0.44 0.26 5.00
147 INT157080 Ghrl Positive_regulation of Localization of Gnrhr 2 0.23 0.7 0.26 5.00
148 INT272997 Binding of CYP3A4 and IL33 1 0.03 0 0.25 5.00
149 INT272998 IL33 Negative_regulation of CYP2D6 1 0.04 0 0.25 5.00
150 INT317251 Npy Positive_regulation of Gpr119 1 0.32 0 0.25 5.00
151 INT296372 Binding of IDUA and ACD 1 0.03 2.72 0.23 5.00
152 INT351318 Binding of CYP2C19 and Cyp1a2 1 0.01 0.28 0.22 5.00
153 INT197811 Binding of SMS and SST 1 0.00 0.98 0.21 5.00
154 INT318039 CDIPT Positive_regulation of CYP3A4 1 0.06 0.06 0.2 5.00
155 INT351086 Negative_regulation of ERBB2 Positive_regulation of Gene_expression of ESR1 1 0.10 0.75 0.19 5.00
156 INT351089 FOXO3 Positive_regulation of Gene_expression of ESR1 1 0.04 0.74 0.19 5.00
157 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 5.00
158 INT330986 CYP2C9 Positive_regulation of Gene_expression of CYP3A4 1 0.39 0 0.18 5.00
159 INT340447 Negative_regulation of IRF6 Positive_regulation of RELA 1 0.00 0.87 0.18 5.00
160 INT290672 Stat3 Negative_regulation of Il6 1 0.08 0.4 0.18 5.00
161 INT330985 CYP2C9 Positive_regulation of Gene_expression of CYP2C19 1 0.34 0 0.18 5.00
162 INT300193 Binding of APOA1 and INSL4 1 0.01 2.17 0.18 5.00
163 INT280052 Negative_regulation of Dpp4 Positive_regulation of Zglp1 1 0.03 0.72 0.18 5.00
164 INT351088 Negative_regulation of ERBB2 Positive_regulation of FOXO3 1 0.17 0.66 0.18 5.00
165 INT325421 PHF20 Positive_regulation of Localization of Gnrhr 1 0.00 0.39 0.17 5.00
166 INT340448 IRF6 Positive_regulation of RELA 1 0.00 0.86 0.17 5.00
167 INT315491 Hspg2 Negative_regulation of Gene_expression of Il4 1 0.04 0.22 0.17 5.00
168 INT290670 Binding of Nos2 and Ppara 1 0.17 0.41 0.16 5.00
169 INT261518 Binding of DLG4 and HTR4 1 0.01 0 0.16 5.00
170 INT229289 FGF19 Negative_regulation of CYP7A1 1 0.26 0.32 0.16 5.00
171 INT350815 Negative_regulation of Binding of TNF and Il1 1 0.05 0.37 0.16 5.00
172 INT261521 Binding of ADCY1 and GLUL 1 0.01 0.09 0.15 5.00
173 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 5.00
174 INT273561 Binding of CYP1A1 and CYP3A4 1 0.02 0.12 0.15 5.00
175 INT278020 Binding of Gh and Sst 1 0.18 0.16 0.15 5.00
176 INT261520 Binding of DLG4 and HTR2A 1 0.06 0 0.14 5.00
177 INT267799 Binding of RLS and ADHD1 1 0.00 4.84 0.14 5.00
178 INT315492 Hspg2 Negative_regulation of Gene_expression of Il2 1 0.06 0.14 0.14 5.00
179 INT344946 AGT Regulation of Negative_regulation of ACE 1 0.21 0.61 0.14 5.00
180 INT227485 pk Positive_regulation of Ptger2 1 0.06 0.91 0.14 5.00
181 INT261519 Binding of HTR4 and USH1C 1 0.00 0 0.13 5.00
182 INT229290 BAS Negative_regulation of LDLR 1 0.03 0.83 0.13 5.00
183 INT299310 RPTOR Positive_regulation of AKT1 1 0.30 0 0.12 5.00
184 INT344947 IPP Regulation of HP 1 0.03 0.81 0.12 5.00
185 INT310695 Binding of Btk and Pla2g6 1 0.18 0.16 0.12 5.00
186 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 5.00
187 INT227400 Binding of DLAT and HCC 1 0.01 2.82 0.11 5.00
188 INT229287 BAS Negative_regulation of CRP 1 0.04 0.36 0.11 5.00
189 INT292087 SRC Regulation of IL8 1 0.02 1.43 0.11 5.00
190 INT317243 Npy Positive_regulation of Tap2 1 0.08 0 0.1 5.00
191 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1 5.00
192 INT317260 Pyy Positive_regulation of Tap2 1 0.09 0 0.1 5.00
193 INT277692 Binding of Atp9a and Tnfrsf10b 1 0.00 1.47 0.1 5.00
194 INT294681 Tlr4 Positive_regulation of Positive_regulation of NFKB1 1 0.02 0.27 0.1 5.00
195 INT280053 Negative_regulation of Dpp4 Negative_regulation of Protein_catabolism of Zglp1 1 0.02 0.71 0.1 5.00
196 INT249117 Binding of Abl1 and Bcr 4 0.36 2.22 0.09 5.00
197 INT315490 Hspg2 Negative_regulation of Il2 1 0.08 0 0.09 5.00
198 INT290673 Ppara Positive_regulation of Gtf3a 1 0.01 0.58 0.09 5.00
199 INT229286 BAS Negative_regulation of FXR1 1 0.02 0.55 0.09 5.00
200 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Constipation. They are ordered first by their pain relevance and then by number of times they were reported in Constipation. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT236867 Gene_expression of AURKC 6 0.55 31.96 1.86 100.00
2 INT326607 Positive_regulation of STC1 1 0.20 3 0.2 100.00
3 INT17817 Binding of VUR 41 0.48 46.85 0.95 100.00
4 INT158070 Localization of Aes 23 0.65 19.93 10.9 100.00
5 INT347935 Positive_regulation of Eea1 1 0.30 0.27 0.05 100.00
6 INT175563 Negative_regulation of NAA50 9 0.16 11.35 1.53 100.00
7 INT66598 Negative_regulation of GPER 8 0.04 3.83 0.72 100.00
8 INT344142 Negative_regulation of Gene_expression of Prss45 1 0.03 1.66 0.69 100.00
9 INT106097 Localization of pr 20 0.62 12.01 19.46 99.96
10 INT241581 Regulation of Htr4 6 0.44 1.34 2.19 99.96
11 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 99.96
12 INT184932 Binding of Sry 1 0.31 2.57 2.28 99.84
13 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 99.80
14 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 99.72
15 INT22239 Negative_regulation of TAC1 52 0.57 12.96 31.41 99.72
16 INT163329 Negative_regulation of GHRL 5 0.58 7.34 0.65 99.68
17 INT4786 Gene_expression of GHRL 7 0.78 7.94 1.76 99.68
18 INT92354 Localization of ESR1 77 0.75 33.04 15.51 99.48
19 INT290175 Positive_regulation of Binding of HAL 1 0.11 0.47 0.05 99.40
20 INT39919 Negative_regulation of MLN 9 0.36 2.91 1.06 99.36
21 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 99.24
22 INT175562 Gene_expression of ENHO 1 0.10 2.85 0.37 99.20
23 INT116501 Binding of ANC 4 0.36 1.8 0.18 99.16
24 INT116500 Binding of OMP 2 0.36 1.46 0.16 99.16
25 INT38066 Binding of MSC 14 0.41 5.28 4.12 99.08
26 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 99.02
27 INT13134 Binding of ADRA2C 11 0.46 0.73 3.86 99.00
28 INT28 Regulation of Gast 106 0.62 26.37 29.85 98.96
29 INT30041 Binding of HAL 8 0.35 2.36 0.95 98.96
30 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 98.88
31 INT65009 Gene_expression of HTR3A 29 0.75 8.51 10.59 98.88
32 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 98.88
33 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 98.76
34 INT1425 Gene_expression of Rbm39 143 0.58 51.32 65.44 98.76
35 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 98.74
36 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 98.72
37 INT100220 Negative_regulation of Src 13 0.41 6.37 4.93 98.72
38 INT158168 Positive_regulation of CLCA2 1 0.04 0.74 0.22 98.56
39 INT3206 Positive_regulation of Got1 39 0.69 19.36 17.02 98.54
40 INT12602 Negative_regulation of Oprm1 190 0.59 36.11 177.85 98.34
41 INT28871 Regulation of CSRP1 8 0.46 6.29 4.04 98.32
42 INT1902 Gene_expression of Cck 348 0.78 70.33 241.92 98.28
43 INT344141 Positive_regulation of Gene_expression of Prss45 1 0.05 1.6 0.68 98.28
44 INT344140 Gene_expression of Prss45 1 0.05 1.6 0.68 98.28
45 INT10604 Gene_expression of SULT1A2 12 0.76 0.72 0.52 98.16
46 INT5660 Binding of Oprd1 477 0.48 71.86 342.06 98.12
47 INT250412 Positive_regulation of Localization of Pyy 3 0.53 0.22 0.25 98.10
48 INT114412 Localization of HCL1 18 0.56 3.69 2.96 98.08
49 INT97984 Negative_regulation of SLC6A4 45 0.59 15.43 18.09 98.04
50 INT91775 Gene_expression of Slc6a4 102 0.78 26.45 28.23 97.92
51 INT145450 Localization of Pyy 7 0.79 0.75 1.14 97.90
52 INT20981 Binding of HRAS 42 0.48 24.49 4.23 97.88
53 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 97.88
54 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 97.68
55 INT92837 Negative_regulation of Gene_expression of Nos2 116 0.59 59.67 31.82 97.60
56 INT236457 Localization of MVP 1 0.31 2.55 0.35 97.60
57 INT37219 Gene_expression of TACR1 56 0.78 32.4 54.16 97.52
58 INT825 Negative_regulation of ADRA1D 54 0.58 20.25 22.78 97.52
59 INT214244 Gene_expression of LAT2 7 0.65 1.24 0.26 97.48
60 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 97.46
61 INT62881 Positive_regulation of Positive_regulation of HTR4 2 0.49 0.96 0.59 97.40
62 INT48688 Positive_regulation of HTR4 12 0.67 1.94 2.81 97.40
63 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 97.40
64 INT77282 Positive_regulation of Cftr 23 0.69 21.8 9.65 97.36
65 INT74726 Negative_regulation of Slc6a4 61 0.59 21.01 27.84 97.32
66 INT273597 Regulation of THSD1 1 0.00 1.06 0.06 97.32
67 INT797 Regulation of Penk 812 0.62 111.13 542.24 97.28
68 INT66531 Gene_expression of Pnoc 88 0.78 22.9 65.11 97.28
69 INT4822 Localization of Ca2 417 0.80 99.57 96.45 97.24
70 INT69350 Gene_expression of RAC1 23 0.77 12.16 5.54 97.12
71 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 97.08
72 INT18156 Gene_expression of Fap 18 0.73 27.02 1.46 97.08
73 INT347936 Regulation of Eea1 1 0.20 0.3 0 97.04
74 INT77804 Regulation of Ednra 9 0.39 2.71 7.94 97.04
75 INT133641 Binding of CCL28 5 0.47 3.23 3.71 96.96
76 INT313773 Negative_regulation of Binding of CCL28 1 0.39 1.05 0.86 96.96
77 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 96.88
78 INT54840 Localization of HTR4 6 0.73 2.67 3.42 96.80
79 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 96.80
80 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 96.76
81 INT2336 Negative_regulation of Lct 51 0.58 33.79 13.73 96.76
82 INT260174 Gene_expression of Rpe65 29 0.78 4.2 0.19 96.76
83 INT93341 Localization of Prkaca 7 0.59 2.04 2.28 96.60
84 INT108708 Binding of Nrp1 3 0.27 3.51 1.08 96.60
85 INT127524 Localization of Zglp1 9 0.53 4.28 1.7 96.60
86 INT134779 Gene_expression of LAX1 1 0.09 0.28 0.09 96.56
87 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 96.54
88 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 96.54
89 INT69484 Positive_regulation of Gene_expression of OPRM1 75 0.70 12.86 52.27 96.40
90 INT11624 Gene_expression of OPRM1 445 0.78 72.36 294.36 96.40
91 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 96.40
92 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 96.40
93 INT12471 Regulation of Insrr 52 0.35 17.8 48.31 96.36
94 INT83236 Localization of PGR 14 0.73 8.26 2.23 96.36
95 INT7346 Localization of Hrh2 15 0.69 5.78 4.79 96.36
96 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 96.28
97 INT812 Localization of INS 1026 0.81 515.6 145.31 96.24
98 INT6884 Negative_regulation of pr 20 0.42 13.18 7.97 96.24
99 INT1322 Positive_regulation of Localization of INS 293 0.70 120.86 45.98 96.24
100 INT1922 Positive_regulation of CEACAM7 32 0.70 33.31 2.72 96.24
101 INT225060 Gene_expression of ITM2B 2 0.43 5.97 2.33 96.20
102 INT115861 Transcription of PRSS3 2 0.67 1.45 1.4 96.12
103 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 96.10
104 INT125974 Localization of Slc6a4 5 0.66 2.27 1.97 96.08
105 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 96.00
106 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 95.92
107 INT76581 Regulation of Negative_regulation of NOS1 14 0.45 7.49 4.4 95.88
108 INT22388 Gene_expression of MLN 15 0.75 4.86 1.14 95.84
109 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 95.68
110 INT77435 Positive_regulation of Nos2 343 0.70 208.49 91.43 95.64
111 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 95.64
112 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 95.64
113 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 95.60
114 INT9311 Regulation of Ssr1 13 0.60 6.41 6.58 95.52
115 INT8388 Positive_regulation of Vip 142 0.70 39.72 67.61 95.48
116 INT2280 Negative_regulation of TNFAIP1 70 0.43 69.43 8.36 95.32
117 INT1281 Negative_regulation of Maoa 203 0.59 22.47 91.66 95.20
118 INT65072 Gene_expression of TKT 16 0.65 17.58 3.55 95.08
119 INT59987 Gene_expression of BDKRB1 25 0.77 11.95 15.93 95.00
120 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 94.96
121 INT137903 Gene_expression of SH3PXD2B 1 0.64 1.76 0.48 94.80
122 INT137904 Regulation of Gene_expression of SH3PXD2B 1 0.22 1.07 0.33 94.80
123 INT22389 Regulation of MLN 9 0.61 4.39 3.08 94.76
124 INT10353 Positive_regulation of PGR 34 0.70 21.84 3.28 94.64
125 INT76869 Localization of PAEP 15 0.73 6.57 3.36 94.52
126 INT76868 Positive_regulation of Localization of PAEP 2 0.33 0.49 0.12 94.52
127 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 94.44
128 INT17934 Localization of MLN 16 0.80 2.83 2.24 94.32
129 INT38241 Positive_regulation of TMPRSS15 1 0.66 0.97 0.18 94.32
130 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 94.16
131 INT2383 Positive_regulation of CP 33 0.67 25.41 15.38 94.12
132 INT132477 Negative_regulation of TSHB 5 0.45 3.24 0.05 94.12
133 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 94.08
134 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 94.08
135 INT201130 Localization of AES 31 0.63 25.45 5.12 94.08
136 INT83035 Binding of INSR 16 0.47 9.29 4.11 94.00
137 INT25022 Binding of PAEP 66 0.42 22.83 6.59 93.92
138 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 93.92
139 INT159137 Localization of T(2;3)24H 1 0.08 0.42 0.31 93.76
140 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 93.72
141 INT264641 Binding of AES 25 0.42 18.56 6.98 93.72
142 INT110348 Negative_regulation of Dpp4 28 0.46 22.39 4.12 93.72
143 INT254298 Protein_catabolism of AES 6 0.55 9.79 1.43 93.72
144 INT169475 Localization of HRAS 14 0.73 9.02 3.9 93.64
145 INT9235 Negative_regulation of Gene_expression of TNF 346 0.59 252.98 118.61 93.60
146 INT19929 Negative_regulation of Positive_regulation of TNF 52 0.59 38.16 16.51 93.60
147 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 93.56
148 INT50291 Positive_regulation of HMBS 10 0.67 8.89 0.73 93.48
149 INT20462 Binding of ESR1 210 0.44 102.7 26.34 93.48
150 INT38056 Localization of Crp 71 0.78 53.14 17.03 93.48
151 INT317231 Negative_regulation of Gpr119 1 0.30 0.34 0.46 93.44
152 INT167705 Positive_regulation of Clcn2 3 0.46 1.32 0.63 93.28
153 INT19422 Protein_catabolism of RIPK2 2 0.86 0.62 0.97 93.28
154 INT137905 Regulation of TKT 2 0.13 1.05 0.32 93.28
155 INT4783 Localization of GHRL 5 0.11 1.28 0.61 93.24
156 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 93.12
157 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 93.12
158 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 93.12
159 INT236865 Positive_regulation of AURKC 3 0.57 18.45 0.54 93.00
160 INT139625 Regulation of Gene_expression of Cftr 5 0.50 3.59 1.32 92.92
161 INT62848 Negative_regulation of GER 8 0.57 3.89 0.93 92.88
162 INT39000 Regulation of pr 24 0.44 12.51 4.36 92.88
163 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 92.88
164 INT343034 Gene_expression of Lbt1 1 0.17 1.31 0.3 92.64
165 INT15007 Gene_expression of Pbrgcsf1 31 0.49 17.82 6.99 92.56
166 INT135132 Positive_regulation of NR1H4 17 0.30 8.63 1.38 92.56
167 INT307060 Negative_regulation of AKTIP 6 0.01 2.79 0.08 92.56
168 INT136397 Gene_expression of bt2 1 0.08 1.29 0.14 92.52
169 INT103842 Gene_expression of Cftr 53 0.78 59.59 21.82 92.36
170 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 92.36
171 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 92.36
172 INT7083 Positive_regulation of HBM 35 0.66 20.96 4.3 92.28
173 INT312307 Positive_regulation of Regulation of HBM 2 0.01 1.94 0.03 92.28
174 INT2365 Positive_regulation of Cck 354 0.70 87.8 277.41 92.24
175 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 92.24
176 INT1495 Positive_regulation of Rtcd1 91 0.54 22.93 32.43 92.20
177 INT312342 Positive_regulation of USH1G 1 0.03 1.97 0.25 92.08
178 INT300268 Regulation of Positive_regulation of LAT2 1 0.31 0.36 0 92.08
179 INT312343 Positive_regulation of Positive_regulation of USH1G 1 0.02 0.98 0.12 92.08
180 INT152461 Negative_regulation of Igh-Dex 2 0.33 0.57 2.22 92.08
181 INT108260 Positive_regulation of Par2 20 0.54 10.77 5.94 92.08
182 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 92.04
183 INT171145 Positive_regulation of Fig4 274 0.59 93.55 69.81 92.00
184 INT186453 Gene_expression of TAB1 6 0.65 4.83 0.35 92.00
185 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 91.92
186 INT6511 Positive_regulation of AFP 76 0.70 70.15 7.28 91.68
187 INT300271 Positive_regulation of LAT2 1 0.36 0.43 0 91.52
188 INT61366 Positive_regulation of NFASC 16 0.26 13.75 4.11 91.52
189 INT28084 Positive_regulation of VIM 49 0.67 35.12 5.15 91.52
190 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 91.52
191 INT91709 Positive_regulation of PGP 4 0.69 1.09 0.77 91.52
192 INT52180 Binding of Aes 38 0.42 23.16 6.7 91.36
193 INT135136 Gene_expression of PEE1 6 0.19 3.9 2.53 91.28
194 INT206779 Regulation of Positive_regulation of PER1 1 0.03 0.18 0.13 91.28
195 INT1261 Localization of Adh1 63 0.81 19.36 16.09 91.08
196 INT50055 Negative_regulation of Rac1 36 0.50 19.74 8.98 91.04
197 INT162873 Negative_regulation of Negative_regulation of Rac1 1 0.34 0.35 0.26 91.04
198 INT173422 Gene_expression of ETFDH 11 0.45 5.78 0.78 91.00
199 INT183753 Regulation of HBM 24 0.39 13.13 1.79 90.96
200 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 90.92
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