D:Deafness

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pChart

Disease Term
Synonyms Acquired Deafness, Bilateral Deafness, Complete Hearing Loss, Deaf, Deaf Mutism, DEAFNESS ACQUIRED, Deafness All Degrees, EXTREME HEARING LOSS, Hearing Loss, HEARING LOSS COMPLETE, Hearing Loss Extreme
Documents 1409
Hot Single Events 200
Hot Interactions 19

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Deafness. They are ordered first by their relevance to Deafness and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29 100.00
2 INT297848 Binding of Fzd4 and Ndp 1 0.04 1.19 0 99.00
3 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0 99.00
4 INT267592 IL6 Positive_regulation of Localization of MUC1 1 0.00 1.24 0.07 98.28
5 INT229785 Binding of RAB7A and SPTLC1 1 0.40 1.5 0.27 97.04
6 INT127545 Gria1 Positive_regulation of Gene_expression of Gnptab 1 0.00 0.7 0.83 96.36
7 INT127543 Gria1 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42 96.36
8 INT127546 Gria1 Positive_regulation of Gene_expression of Kcnab3 1 0.02 0.35 0.42 96.36
9 INT77957 Binding of RUNX1T1 and DEAF1 1 0.20 0.36 0 94.52
10 INT77958 Binding of RUNX1 and DEAF1 1 0.20 0.36 0 94.52
11 INT77956 Binding of PENK and DEAF1 1 0.21 0.22 0 93.48
12 INT153740 TNFRSF11A Positive_regulation of Vcp 1 0.04 1.15 0.13 91.16
13 INT153739 TNFRSF11A Positive_regulation of Tnfrsf11b 1 0.05 1.14 0.13 91.16
14 INT153742 TNFRSF11A Positive_regulation of Tnfrsf11b 1 0.00 1.15 0.13 91.16
15 INT153738 TNFRSF11A Positive_regulation of SQSTM1 1 0.05 1.22 0.13 91.16
16 INT267585 TNF Regulation of IL6 2 0.16 2.44 0.37 85.68
17 INT94939 Binding of POMC and B3GAT1 1 0.40 1.04 0.12 84.08
18 INT94938 Binding of SERPINB1 and B3GAT1 1 0.01 1.04 0.12 84.08
19 INT321770 Binding of Myo15 and Whrn 1 0.43 0.08 0 80.52
20 INT355327 Binding of Nes and Prom1 1 0.11 1.49 0.06 75.96
21 INT256706 Binding of Hsp90b1 and Wfs1 1 0.43 5.02 0.2 75.04
22 INT77963 Binding of DEAF1 and Rare1 1 0.01 0.28 0 75.00
23 INT252857 Binding of F2rl1 and Trpa1 1 0.22 0.84 0.63 70.00
24 INT252859 Binding of Ngf and Trpa1 1 0.19 0.84 0.62 66.64
25 INT267623 IL6 Positive_regulation of Crp 1 0.00 1.6 0.24 60.32
26 INT352297 Regulation of Binding of CD99 and VIM 1 0.19 1.07 0.06 59.88
27 INT352299 Regulation of Binding of BCL2 and VIM 1 0.10 1.07 0.06 59.88
28 INT352296 Binding of CD99 and VIM 1 0.16 1.06 0.06 59.12
29 INT352298 Binding of BCL2 and VIM 1 0.09 1.06 0.06 59.12
30 INT321778 Binding of P4hb and Whrn 1 0.33 0.06 0 58.88
31 INT259023 CADPS Positive_regulation of Binding of SH2B2 1 0.06 2.05 0.14 55.00
32 INT328667 Binding of CD40LG and CSF2 1 0.16 0.59 0.05 53.68
33 INT328668 Binding of CSF2 and IGHG3 1 0.03 0.59 0.05 53.68
34 INT256707 Eif2ak3 Regulation of Gene_expression of Wfs1 1 0.10 0.78 0.03 40.32
35 INT217478 Binding of Tnfrsf11a and Traf6 1 0.39 1.22 0.17 36.48
36 INT237669 Binding of PDB1 and SQSTM1 1 0.27 2.55 0 34.68
37 INT293867 Binding of COL2A1 and MEFV 1 0.01 0.52 0.14 34.32
38 INT252858 C5 Negative_regulation of Positive_regulation of Trpa1 1 0.02 0.78 0.74 32.20
39 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 26.52
40 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 26.52
41 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14 17.88
42 INT321771 Binding of P4hb and Gsn 1 0.31 0.38 0 15.36
43 INT237670 SQSTM1 Regulation of PDB1 1 0.34 1.13 0.06 11.76
44 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
45 INT262558 Phax Positive_regulation of Trpv1 1 0.01 1.26 1.92 5.00
46 INT93293 Ngf Regulation of Trpv1 2 0.28 0.71 1.9 5.00
47 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
48 INT121226 Ngf Regulation of Gene_expression of Trpv1 2 0.62 0.7 1.44 5.00
49 INT262568 Prkaca Regulation of Trpv1 2 0.10 0.65 1.38 5.00
50 INT267588 IL10 Negative_regulation of Gene_expression of IL6 1 0.01 2.25 1.11 5.00
51 INT267597 IL10 Negative_regulation of Gene_expression of TNF 1 0.03 2.24 1.1 5.00
52 INT271635 Negative_regulation of GRIN1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.65 0.93 5.00
53 INT262572 Ngf Positive_regulation of Mapk1 2 0.04 0.52 0.81 5.00
54 INT262564 Ngf Positive_regulation of Pik3r1 1 0.08 0.36 0.8 5.00
55 INT262579 Ngf Positive_regulation of Prkca 1 0.07 0.36 0.8 5.00
56 INT262582 F2rl1 Regulation of Positive_regulation of Prkca 1 0.03 0.58 0.78 5.00
57 INT262562 F2rl1 Regulation of Trpv1 1 0.12 0.58 0.77 5.00
58 INT262563 Negative_regulation of Pax3 Regulation of Calca 1 0.01 0.75 0.76 5.00
59 INT262569 Pax3 Regulation of Calca 1 0.00 0.75 0.76 5.00
60 INT262577 Localization of Ngf Positive_regulation of Positive_regulation of Mapk14 1 0.05 0.92 0.75 5.00
61 INT262578 Prkaca Positive_regulation of Localization of Calca 1 0.03 0.71 0.75 5.00
62 INT262573 Par2 Regulation of Positive_regulation of Prkca 1 0.05 0.57 0.72 5.00
63 INT262580 Ngf Positive_regulation of Hspg2 1 0.03 0.35 0.72 5.00
64 INT262581 Prkca Positive_regulation of Phosphorylation of Trpv1 1 0.13 0.28 0.71 5.00
65 INT267630 Il1 Regulation of Gene_expression of IL8 1 0.00 0.44 0.71 5.00
66 INT262574 Gnaq Positive_regulation of Prkca 1 0.00 0.57 0.71 5.00
67 INT262566 Par2 Regulation of Trpv1 1 0.20 0.57 0.71 5.00
68 INT262571 Phosphorylation of Trpv1 Positive_regulation of Localization of Calca 1 0.17 0.71 0.7 5.00
69 INT110835 Binding of SPTLC2 and SPTLC1 2 0.42 1.36 0.68 5.00
70 INT262570 Binding of Pax3 and Trpv1 1 0.02 1.05 0.67 5.00
71 INT262576 Binding of Calca and Trpv1 1 0.13 1.05 0.66 5.00
72 INT25248 GNRH1 Regulation of CGA 4 0.30 1.22 0.62 5.00
73 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 5.00
74 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
75 INT333476 IL12B Positive_regulation of Localization of AFP 1 0.03 0.26 0.57 5.00
76 INT333477 CXCL10 Positive_regulation of TH1L 1 0.14 0.32 0.56 5.00
77 INT171905 TNF Positive_regulation of Gene_expression of Il1 2 0.23 1.08 0.54 5.00
78 INT262565 Prkaca Regulation of Negative_regulation of Trpv1 1 0.05 0.21 0.5 5.00
79 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
80 INT262575 Trpv1 Positive_regulation of Prkca 1 0.13 0.17 0.44 5.00
81 INT181862 Binding of MPO and PRTN3 2 0.16 1.18 0.38 5.00
82 INT267595 IL12A Positive_regulation of IFN1@ 1 0.03 0.69 0.36 5.00
83 INT110834 Binding of AGXT and SPTLC2 2 0.27 0.71 0.36 5.00
84 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34 5.00
85 INT318299 Binding of F2 and PRTN3 1 0.01 1.92 0.33 5.00
86 INT229635 SPINK5 Positive_regulation of NF1 1 0.01 2.17 0.3 5.00
87 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
88 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
89 INT325530 Positive_regulation of Gsk3b Negative_regulation of Gene_expression of Wnt2 1 0.03 0.63 0.28 5.00
90 INT267628 IL4 Positive_regulation of IgG 1 0.00 1.42 0.27 5.00
91 INT267586 IL4 Positive_regulation of IGHE 1 0.00 1.42 0.27 5.00
92 INT267632 Il1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.86 0.25 5.00
93 INT267624 Klk1 Positive_regulation of KNG1 1 0.05 0.52 0.25 5.00
94 INT267584 TNF Positive_regulation of Gene_expression of PLA2G6 1 0.08 0.87 0.25 5.00
95 INT267631 IRF6 Positive_regulation of Gene_expression of Il1 1 0.00 0.96 0.25 5.00
96 INT267596 KNG1 Positive_regulation of Gene_expression of PLA2G6 1 0.01 0.87 0.25 5.00
97 INT267591 CYSLTR1 Positive_regulation of Gene_expression of PLA2G6 1 0.00 0.87 0.25 5.00
98 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
99 INT318303 Negative_regulation of Myoz1 Negative_regulation of Transcription of IL2 1 0.00 0.75 0.21 5.00
100 INT269180 LEP Positive_regulation of Localization of TNF 1 0.01 0.99 0.21 5.00
101 INT325529 Binding of Stat3 and Ep300 1 0.01 0.22 0.19 5.00
102 INT325531 Positive_regulation of Binding of Stat3 and Ep300 1 0.02 0.22 0.19 5.00
103 INT229634 GOPC Positive_regulation of GAST 1 0.09 0.47 0.19 5.00
104 INT318298 MECOM Negative_regulation of Binding of CD28 1 0.00 1.08 0.18 5.00
105 INT267629 PTAFR Positive_regulation of Localization of Il1 1 0.00 1.32 0.18 5.00
106 INT267627 Il1 Positive_regulation of Gene_expression of TNF 1 0.02 0.45 0.17 5.00
107 INT325532 Binding of Cx3cl1 and Cxcl10 1 0.28 0.67 0.16 5.00
108 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15 5.00
109 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15 5.00
110 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
111 INT302676 Binding of OPA1 and MFN2 1 0.46 1.12 0.14 5.00
112 INT315030 Binding of Cav1 and Tmie 1 0.03 0.25 0.14 5.00
113 INT220305 Binding of IL6 and IL10 1 0.00 0.51 0.14 5.00
114 INT315032 Binding of Cav1 and Ryr1 1 0.27 0.2 0.14 5.00
115 INT355330 Regulation of Gtf3a Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.9 0.12 5.00
116 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
117 INT217470 Traf6 Positive_regulation of Ngf 1 0.36 0.52 0.1 5.00
118 INT217476 Nup62 Positive_regulation of Ngf 1 0.37 0.52 0.1 5.00
119 INT267587 PTAFR Positive_regulation of Localization of PTPRC 1 0.00 2.04 0.09 5.00
120 INT217477 Traf6 Positive_regulation of Binding of Nup62 1 0.32 0.47 0.09 5.00
121 INT267626 Il1 Positive_regulation of ICAM1 1 0.00 0.79 0.09 5.00
122 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
123 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
124 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
125 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
126 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
127 INT267618 Il1 Positive_regulation of Vcam1 1 0.00 0.81 0.09 5.00
128 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
129 INT217486 Binding of PDB1 and Sqstm1 1 0.03 1.19 0.08 5.00
130 INT268679 Binding of HDAC1 and NCOR2 3 0.17 2.8 0.07 5.00
131 INT250153 Binding of PRNP and IKBKG 1 0.09 2.83 0.06 5.00
132 INT250150 Binding of IKBKG and SACM1L 1 0.00 2.78 0.06 5.00
133 INT267593 IL8 Positive_regulation of Localization of MUC1 1 0.00 1.06 0.06 5.00
134 INT217472 Binding of Nup62 and Mul1 1 0.12 0 0.05 5.00
135 INT217471 Binding of Nup62 and Traf6 1 0.26 0 0.05 5.00
136 INT275126 Binding of CSTB and IGHG3 1 0.00 0.49 0.05 5.00
137 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
138 INT217468 Positive_regulation of Binding of Nup62 and Mul1 1 0.16 0 0.05 5.00
139 INT214847 Binding of VWF and ANGPTL5 1 0.03 1.16 0.05 5.00
140 INT297850 Snx1 Positive_regulation of Protein_catabolism of P9Ehs1 1 0.01 0.31 0.05 5.00
141 INT217467 Binding of Nup62 and Tnfrsf11a 1 0.31 0 0.05 5.00
142 INT217474 Tnfrsf11a Regulation of Gene_expression of Tnfsf11 1 0.41 1.2 0.04 5.00
143 INT250151 Binding of GSS and MCM3 1 0.01 1.38 0.04 5.00
144 INT275125 Binding of HLA-DOA and HSPG2 1 0.01 1.42 0.04 5.00
145 INT313273 Binding of GRIN1 and MAP2 1 0.16 0.79 0.04 5.00
146 INT275124 Binding of HSPG2 and LTA 1 0.12 1.45 0.04 5.00
147 INT247819 Cxadr Regulation of Gene_expression of Rasa1 1 0.06 1.04 0.04 5.00
148 INT276583 Binding of Wt1 and IgG 1 0.07 0 0.04 5.00
149 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
150 INT284916 IL1RN Negative_regulation of HDAC4 1 0.00 1.66 0.03 5.00
151 INT293559 Binding of CALM1 and Aqp6 1 0.01 0 0.03 5.00
152 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 5.00
153 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
154 INT315034 Ass1 Positive_regulation of Cacna1f 1 0.00 0 0.03 5.00
155 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
156 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 5.00
157 INT352175 USE1 Regulation of NAGA 1 0.01 0.33 0 5.00
158 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0 5.00
159 INT256703 Negative_regulation of Hsp90b1 Positive_regulation of Wfs1 1 0.42 0.24 0 5.00
160 INT293869 Binding of COL2A1 and GREM1 1 0.00 1.11 0 5.00
161 INT276586 Binding of Wt1 and Actn1 1 0.34 0.41 0 5.00
162 INT247821 Binding of Tjp1 and Gopc 1 0.03 0.4 0 5.00
163 INT256700 Negative_regulation of Binding of Hsp90b1 and Wfs1 1 0.52 0 0 5.00
164 INT217473 Nup62 Regulation of Tnfrsf11a 1 0.38 0.66 0 5.00
165 INT275123 Binding of HLA-E and SUGT1 1 0.00 0.93 0 5.00
166 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
167 INT321781 Whrn Positive_regulation of Gopc 1 0.18 0 0 5.00
168 INT284919 XRCC6 Negative_regulation of BAX 1 0.01 0.64 0 5.00
169 INT277555 Clrn1 Regulation of Localization of Pdc 1 0.05 0.7 0 5.00
170 INT284920 Binding of HDAC1 and NCOR1 1 0.03 0.13 0 5.00
171 INT315033 Binding of Calm3 and Vsig2 1 0.00 0 0 5.00
172 INT313271 Binding of GRIN1 and GRIN2B 1 0.24 0.06 0 5.00
173 INT321783 Binding of Pi4kb and Gsn 1 0.03 0 0 5.00
174 INT282630 Binding of CISH and UGT2B17 1 0.04 0 0 5.00
175 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
176 INT284918 RUNX1T1 Regulation of DNMT1 1 0.21 1.09 0 5.00
177 INT284917 RUNX1T1 Regulation of HDAC9 1 0.19 1.09 0 5.00
178 INT276585 Binding of Trpc5 and Trpc6 1 0.17 0.26 0 5.00
179 INT273136 Binding of CHED1 and VSX1 1 0.15 0.12 0 5.00
180 INT321772 Binding of Myo7a and Twf2 1 0.00 0 0 5.00
181 INT284914 Binding of HDAC1 and NCK1 1 0.00 0.13 0 5.00
182 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
183 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0 5.00
184 INT247823 Binding of Cxadr and Tjp1 1 0.08 0.4 0 5.00
185 INT351873 NR4A1 Positive_regulation of EXOSC1 1 0.04 0 0 5.00
186 INT293868 Binding of GREM1 and OCM 1 0.00 1.11 0 5.00
187 INT321773 Binding of Shbdp1 and Positive_regulation of Ablim1 1 0.01 0 0 5.00
188 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00
189 INT228002 Binding of Loxl1 and Fbln5 1 0.34 1.57 0 5.00
190 INT217487 Binding of PDB1 and Tnfrsf11a 1 0.03 0.76 0 5.00
191 INT313272 Binding of DLG4 and GRIN1 1 0.09 0.06 0 5.00
192 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00
193 INT256701 Binding of Hsp90aa1 and Hsp90b1 1 0.12 0.34 0 5.00
194 INT321776 Whrn Regulation of Localization of Gsn 1 0.23 0.07 0 5.00
195 INT315029 Binding of Calm3 and Cacna1f 1 0.04 0 0 5.00
196 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
197 INT217480 Tnfsf11 Negative_regulation of Tnfrsf11a 1 0.39 0.75 0 5.00
198 INT297854 Agrp Regulation of Pomc 1 0.24 0 0 5.00
199 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
200 INT302675 Binding of OPA1 and PLAA 1 0.15 0.73 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Deafness. They are ordered first by their pain relevance and then by number of times they were reported in Deafness. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT172328 Negative_regulation of Phl1 1 0.03 61.51 0.97 100.00
2 INT172323 Gene_expression of Phl1 1 0.03 14 0.16 100.00
3 INT277526 Gene_expression of Clrn1 1 0.78 29.02 0.17 100.00
4 INT267905 Localization of TCHH 1 0.66 2.02 0.13 100.00
5 INT35584 Binding of ACLY 22 0.35 31.78 7.17 100.00
6 INT172321 Localization of Phl1 1 0.03 1.41 0 100.00
7 INT267903 Negative_regulation of TCHH 1 0.37 1.54 0.15 100.00
8 INT259037 Negative_regulation of Binding of ACLY 1 0.07 1.54 0.13 100.00
9 INT251801 Negative_regulation of Spl 1 0.37 1.13 0 100.00
10 INT267904 Binding of TCHH 1 0.33 0.96 0 100.00
11 INT259030 Negative_regulation of Gene_expression of ACLY 1 0.07 1.95 0.08 100.00
12 INT277546 Negative_regulation of Clrn1 1 0.51 2.42 0 100.00
13 INT267906 Positive_regulation of TCHH 1 0.44 0.76 0 100.00
14 INT251821 Negative_regulation of COL11A1 3 0.42 3.45 0.16 100.00
15 INT100125 Negative_regulation of Accn3 11 0.59 5.85 4.32 100.00
16 INT23171 Negative_regulation of NLRP3 7 0.37 4.15 1.53 100.00
17 INT158863 Negative_regulation of Ros1 84 0.35 40.3 10.14 100.00
18 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 100.00
19 INT172327 Binding of Phl1 1 0.02 0.29 0 100.00
20 INT148299 Negative_regulation of KCNQ4 2 0.11 0.37 0.24 100.00
21 INT162563 Gene_expression of NFATC2 2 0.38 0.85 0.24 100.00
22 INT162564 Gene_expression of KRT2 5 0.59 1.75 0.24 100.00
23 INT261721 Negative_regulation of Stl2 1 0.07 1.38 0.16 100.00
24 INT266512 Negative_regulation of Hoxb6 1 0.07 0.82 0.08 100.00
25 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 99.98
26 INT277524 Binding of Clrn1 1 0.37 1.9 0 99.92
27 INT14572 Binding of INS 205 0.48 175.43 13.38 99.84
28 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 99.64
29 INT85624 Gene_expression of GJB1 5 0.78 3.03 0.93 99.60
30 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 99.58
31 INT236517 Gene_expression of Cacna1f 8 0.65 5.18 0.77 99.52
32 INT21685 Gene_expression of ras 115 0.66 85.6 7.76 99.40
33 INT231944 Regulation of FOXP2 2 0.62 0.89 0.31 99.36
34 INT232567 Binding of Spl 2 0.31 1.88 0.1 99.36
35 INT334578 Binding of SLC26A4 1 0.21 0.83 0 99.36
36 INT273144 Binding of CHED1 1 0.19 1.7 0 99.36
37 INT234577 Positive_regulation of Gene_expression of MRP63 1 0.10 0.58 0 99.34
38 INT290684 Gene_expression of FOXP2 1 0.78 1.78 0.03 99.08
39 INT290688 Negative_regulation of FOXP2 1 0.59 1.11 0.04 99.08
40 INT290683 Negative_regulation of Negative_regulation of FOXP2 1 0.43 0.31 0 99.08
41 INT234575 Gene_expression of MRP63 1 0.16 0.62 0 99.04
42 INT297823 Gene_expression of Ndp 1 0.63 2.51 0 99.00
43 INT349979 Negative_regulation of CCKBR 1 0.16 4.34 0.22 98.96
44 INT25022 Binding of PAEP 66 0.42 22.83 6.59 98.96
45 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 98.76
46 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 98.72
47 INT293876 Localization of OCM 1 0.05 0.7 0.1 98.64
48 INT11947 Binding of CCKBR 1 0.36 0.42 0.53 98.56
49 INT121110 Binding of neuropathy type 1 1 0.01 0.66 0.33 98.44
50 INT94450 Gene_expression of Nav1 359 0.78 131.85 275.46 98.36
51 INT16150 Positive_regulation of NKG7 10 0.69 10.26 1.73 98.36
52 INT65375 Positive_regulation of CCKBR 2 0.67 1.71 0.3 98.28
53 INT21687 Positive_regulation of ras 143 0.58 97.34 27.31 98.28
54 INT49802 Localization of MUC1 75 0.81 44.74 8.87 98.28
55 INT60766 Gene_expression of COL4A4 10 0.77 13.46 1.14 98.16
56 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 98.08
57 INT77670 Positive_regulation of ACLY 24 0.49 21.68 3.12 98.08
58 INT153758 Binding of Mitf 5 0.47 2.5 0.46 98.00
59 INT300329 Regulation of Binding of Mitf 1 0.24 0.27 0 98.00
60 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 97.92
61 INT172325 Positive_regulation of Gene_expression of Phl1 1 0.02 2.65 0.04 97.68
62 INT277539 Positive_regulation of Clrn1 1 0.50 4.04 0 97.52
63 INT290686 Regulation of Gene_expression of FOXP2 1 0.62 0.63 0 97.52
64 INT89774 Gene_expression of NR4A1 13 0.77 9.47 1.02 97.52
65 INT169670 Gene_expression of PHARC 1 0.14 1.41 0.35 97.40
66 INT70957 Binding of OAT 1 0.11 0.53 0.09 97.40
67 INT106433 Regulation of CCR5 11 0.59 6.93 2.75 97.36
68 INT172322 Negative_regulation of Gene_expression of Nt5e 1 0.41 1.03 0.04 97.32
69 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17 97.28
70 INT33220 Negative_regulation of ras 110 0.58 70.21 9.19 97.24
71 INT95670 Regulation of PDB1 4 0.60 5.59 0.55 97.24
72 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 97.08
73 INT143835 Gene_expression of Foxc1 2 0.39 1.17 0.09 97.04
74 INT143836 Negative_regulation of Foxc1 1 0.35 0.92 0.09 97.04
75 INT158837 Binding of POLG 4 0.37 4.69 0.44 96.92
76 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 96.84
77 INT19391 Gene_expression of Nt5e 44 0.72 13.99 5.14 96.64
78 INT143830 Gene_expression of Barx1 1 0.23 0.91 0.09 96.60
79 INT143831 Negative_regulation of Barx1 1 0.16 0.91 0.09 96.60
80 INT267670 Regulation of Nexn 4 0.39 3.95 0.04 96.56
81 INT65914 Gene_expression of Gnptab 7 0.04 1.13 5.44 96.36
82 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37 96.36
83 INT91930 Gene_expression of Kcnab3 10 0.16 4.41 7.77 96.36
84 INT127539 Positive_regulation of Gene_expression of Cryge 1 0.00 0.35 0.42 96.36
85 INT127540 Gene_expression of Cryge 1 0.01 0.35 0.38 96.36
86 INT143837 Negative_regulation of Pitx2 1 0.19 0.91 0.09 96.32
87 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 96.32
88 INT57562 Gene_expression of GLA 52 0.77 24.62 6.14 96.28
89 INT57560 Positive_regulation of GLA 14 0.54 5.01 0.83 96.28
90 INT148298 Negative_regulation of Kcna7 2 0.05 0.36 0.22 96.20
91 INT216121 Gene_expression of NOX3 1 0.63 2.04 0.33 96.12
92 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 95.80
93 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 95.76
94 INT133842 Binding of SOX10 3 0.38 5.79 1.02 95.44
95 INT77962 Binding of DEAF1 1 0.27 0.47 0 95.20
96 INT103043 Binding of PDE5A 16 0.37 7.79 1.12 95.04
97 INT274268 Localization of OPA2 1 0.12 1.48 0 94.96
98 INT70954 Negative_regulation of Cd3e 11 0.41 4.22 1.31 94.64
99 INT70955 Negative_regulation of Negative_regulation of Cd3e 1 0.41 0.47 0.09 94.64
100 INT9732 Regulation of COL2A1 9 0.58 6.93 0.44 94.52
101 INT209503 Positive_regulation of CADPS 3 0.42 7 1.11 94.36
102 INT27313 Negative_regulation of OAT 2 0.17 0.69 0.46 94.04
103 INT70956 Negative_regulation of Negative_regulation of OAT 1 0.13 0.47 0.09 94.04
104 INT48882 Binding of GRIN3B 9 0.46 5.12 7.66 93.88
105 INT123978 Binding of GRIA1 3 0.41 3.5 2.62 93.88
106 INT334577 Binding of KCNE1L 1 0.27 1.33 0 93.76
107 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 93.76
108 INT199641 Regulation of Transcription of Fxn 1 0.29 1.89 0.04 93.72
109 INT199648 Regulation of Fxn 1 0.29 2.14 0.04 93.72
110 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 93.64
111 INT1590 Binding of PENK 27 0.47 2.99 12.81 93.48
112 INT102696 Binding of MRP63 4 0.46 3.68 0.27 93.48
113 INT109430 Positive_regulation of Trpa1 119 0.70 44 49.14 93.40
114 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 93.04
115 INT199646 Transcription of Fxn 2 0.67 4.78 0.08 93.04
116 INT277552 Gene_expression of Whrn 2 0.57 0.75 0.04 92.72
117 INT53021 Positive_regulation of COL2A1 29 0.55 27.75 3.47 92.48
118 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 92.28
119 INT42469 Regulation of LNPEP 9 0.60 0.46 0.83 92.16
120 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 91.96
121 INT79556 Gene_expression of GRIN3B 16 0.77 7.71 10.75 91.76
122 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11 91.76
123 INT78515 Negative_regulation of Mag 10 0.54 9.4 5.06 91.24
124 INT569 Negative_regulation of C4a 13 0.42 9.48 2.85 91.24
125 INT59365 Gene_expression of HTR1A 41 0.75 16.31 16.57 91.20
126 INT309839 Binding of Nlrp1a 5 0.29 1.95 0.38 91.20
127 INT110210 Negative_regulation of CSRP1 12 0.59 8.96 2.81 91.08
128 INT101653 Negative_regulation of SAA1 7 0.39 7 1.33 91.08
129 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 91.08
130 INT126114 Regulation of Kcna7 5 0.07 2.08 0.69 91.00
131 INT99095 Binding of COL4A4 7 0.37 3.51 0.29 90.80
132 INT293188 Gene_expression of MIR206 2 0.19 1.46 0.05 90.72
133 INT287085 Negative_regulation of Myh9 1 0.21 0.6 0.03 90.72
134 INT129771 Regulation of SMARCB1 5 0.58 8.92 0.58 90.68
135 INT271570 Gene_expression of MIR1-1 21 0.65 11.49 1.03 90.24
136 INT2867 Gene_expression of CALCA 247 0.78 78.78 138.47 90.12
137 INT72298 Localization of Xpa 1 0.08 0.73 0.29 90.04
138 INT72299 Gene_expression of Xpa 1 0.07 0.73 0.29 90.04
139 INT90171 Positive_regulation of HNB1 1 0.00 0.57 0.32 90.00
140 INT6507 Binding of C5 23 0.48 15.35 3.91 89.96
141 INT131066 Binding of C6 4 0.31 1.81 0.86 89.96
142 INT90168 Regulation of Wnk1 2 0.04 0.63 0.29 89.92
143 INT90170 Regulation of HNB1 1 0.00 0.56 0.29 89.92
144 INT77959 Binding of Rare1 3 0.04 1.26 0.27 89.84
145 INT20299 Protein_catabolism of C2 3 0.87 1.56 0.1 89.84
146 INT309244 Transcription of HSPA5 1 0.16 2.75 0.36 89.80
147 INT8224 Gene_expression of CHGA 73 0.75 53.63 12.31 89.76
148 INT6810 Gene_expression of ENO2 70 0.78 54.8 8.35 89.76
149 INT15652 Positive_regulation of ENO2 37 0.68 33.39 5.02 89.76
150 INT18898 Positive_regulation of CHGA 38 0.67 28.99 4.86 89.76
151 INT48219 Gene_expression of SLC4A1 34 0.75 33.18 2.84 89.76
152 INT48217 Gene_expression of SLC4A3 22 0.75 21.12 2.17 89.76
153 INT72296 Localization of Gas1 1 0.50 0.73 0.29 89.72
154 INT72297 Gene_expression of Gas1 1 0.48 0.73 0.29 89.72
155 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 89.52
156 INT178547 Gene_expression of CSTB 9 0.29 6.53 0.18 89.44
157 INT178535 Regulation of Gene_expression of CSTB 2 0.19 2.91 0.06 89.44
158 INT57501 Binding of CREM 11 0.27 3.67 2.15 89.36
159 INT143833 Positive_regulation of Foxc1 2 0.42 1.02 0.09 89.24
160 INT143832 Positive_regulation of Barx1 1 0.19 0.86 0.09 89.24
161 INT143834 Positive_regulation of Pitx2 1 0.22 0.86 0.09 89.24
162 INT127538 Negative_regulation of Gene_expression of Glra1 1 0.02 0.33 0.49 89.16
163 INT127541 Gene_expression of Glra1 1 0.04 0.33 0.46 89.16
164 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 89.16
165 INT297836 Negative_regulation of Ndp 1 0.41 1.8 0 88.80
166 INT99961 Positive_regulation of SYP 13 0.67 15.13 2.79 88.76
167 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 88.76
168 INT16997 Binding of PRTN3 34 0.48 33.44 6.45 88.76
169 INT14515 Positive_regulation of Lrrc23 8 0.28 8.51 0.97 88.76
170 INT126220 Positive_regulation of CENPV 2 0.49 1.52 0.17 88.76
171 INT194031 Regulation of SQSTM1 2 0.41 2.07 0.27 88.64
172 INT194030 Regulation of UBAP1 1 0.03 1.34 0.13 88.64
173 INT65262 Gene_expression of Lox 47 0.74 36.59 5.65 88.44
174 INT76227 Binding of NPC1 30 0.41 32.31 4.05 88.28
175 INT60197 Gene_expression of JUN 90 0.78 42.32 14.61 88.04
176 INT169669 Positive_regulation of PHARC 1 0.12 1.34 0.3 88.00
177 INT4993 Gene_expression of Lrrc23 13 0.66 11.04 1.99 87.92
178 INT14301 Binding of CSF2 82 0.48 67.95 8.98 87.88
179 INT86705 Gene_expression of BTG3 41 0.65 37.29 8.29 87.80
180 INT293874 Positive_regulation of OCM 1 0.05 2 0 87.80
181 INT290685 Negative_regulation of Gene_expression of FOXP2 1 0.59 0.3 0 87.76
182 INT77247 Binding of WNK1 5 0.46 3.45 0.7 87.76
183 INT161702 Gene_expression of GJB2 3 0.65 2.19 0.14 87.68
184 INT256366 Gene_expression of GJB6 2 0.50 0.8 0 87.68
185 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 87.60
186 INT68781 Negative_regulation of TFAM 15 0.58 10.01 2.42 87.20
187 INT85854 Binding of SALL1 5 0.36 1.4 0.41 87.12
188 INT24891 Gene_expression of SYP 55 0.75 45.76 7.53 86.92
189 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 86.88
190 INT120227 Binding of Cxadr 17 0.45 8.02 1.51 86.76
191 INT13790 Binding of HTR1A 52 0.47 18.83 17.59 86.72
192 INT133841 Gene_expression of SOX10 18 0.67 9.96 0.8 86.68
193 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 86.68
194 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 86.68
195 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 86.68
196 INT157500 Localization of DNMT3B 12 0.73 2.21 1.38 86.04
197 INT17032 Positive_regulation of Ttr 7 0.50 3.87 1.2 85.96
198 INT297804 Regulation of Lrp5 6 0.60 2.31 0.27 85.88
199 INT297821 Regulation of Fzd4 1 0.03 0.57 0 85.88
200 INT297820 Regulation of Transcription of Lrp5 2 0.44 0.83 0 85.88
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