D:Dermatofibroma

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pChart

Disease Term
Synonyms Angioma Sclerosing, Angiomas Sclerosing, Benign Fibrous Histiocytoma, Benign Fibrous Histiocytomas, Cutaneous Histiocytoma, Cutaneous Histiocytomas, Dermatofibroma Lenticulare, Dermatofibromas, Fibrous Histiocytoma, Fibrous Histiocytoma Benign, Fibrous Histiocytomas
Documents 85
Hot Single Events 25
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Dermatofibroma. They are ordered first by their relevance to Dermatofibroma and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT296684 Binding of CD99 and Bcl2 1 0.01 1.68 0 58.68
2 INT322413 Binding of ATF1 and EWSR1 1 0.26 1.3 0 31.44
3 INT137398 Binding of CD99 and Vim 2 0.02 2.36 0.09 10.52
4 INT296670 Binding of Bcl2 and Vim 1 0.00 1.31 0 10.52
5 INT321598 Binding of MLL and TNF 1 0.05 1.07 0.49 5.00
6 INT263917 Binding of SST and Sstr5 2 0.02 0.56 0.45 5.00
7 INT263901 Binding of Ighg1 and Slc3a2 1 0.00 0.89 0.16 5.00
8 INT276228 Nrtim1 Positive_regulation of PPARG 1 0.01 2.18 0.14 5.00
9 INT263900 Binding of Col1a1 and Cea 1 0.01 0.63 0 5.00
10 INT263918 Binding of PTPRC and Cea 1 0.00 0.37 0 5.00
11 INT277703 Binding of Pdgfrb and Pdgfb 1 0.02 0.23 0 5.00
12 INT263899 Binding of PTPRC and TMED7-TICAM2 1 0.00 0.85 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Dermatofibroma. They are ordered first by their pain relevance and then by number of times they were reported in Dermatofibroma. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 99.66
2 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 99.64
3 INT162666 Gene_expression of ST3 5 0.67 5.66 1.73 99.36
4 INT899 Gene_expression of F13A1 122 0.70 78.02 16.26 99.34
5 INT21681 Positive_regulation of CD34 54 0.66 33.95 4.14 98.82
6 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 98.16
7 INT5841 Gene_expression of Vim 181 0.72 138.54 16.33 97.48
8 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 97.00
9 INT52937 Gene_expression of Cd68 37 0.67 31.33 7.54 96.96
10 INT105148 Positive_regulation of Gene_expression of TNC 6 0.50 6.45 1.8 96.88
11 INT25963 Gene_expression of DES 122 0.75 98.81 11.25 96.60
12 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 96.60
13 INT49325 Gene_expression of Cd34 102 0.78 82.75 8.97 96.60
14 INT23955 Regulation of Vim 16 0.25 14.21 2.04 96.00
15 INT78877 Gene_expression of EWSR1 10 0.75 11.16 0.97 94.64
16 INT6667 Gene_expression of CREB1 27 0.77 6.29 5.84 94.64
17 INT54546 Binding of CREB1 9 0.41 3.44 0.72 94.64
18 INT322421 Gene_expression of ATF1 2 0.39 1.41 0.05 94.64
19 INT263905 Gene_expression of SLN 33 0.63 23.21 0.74 91.76
20 INT76315 Gene_expression of Myog 15 0.41 6.79 0.6 88.36
21 INT176594 Gene_expression of SRA1 20 0.35 9.65 1.15 84.76
22 INT265794 Regulation of SRA1 3 0.23 3.05 0.35 84.76
23 INT142829 Transcription of CREB1 9 0.46 3.37 1.03 83.92
24 INT104143 Transcription of EWSR1 7 0.67 8.1 0.42 83.92
25 INT67613 Positive_regulation of PPARG 94 0.70 69.15 34.38 83.52
26 INT22092 Gene_expression of SERPINA3 17 0.75 11.57 3.16 77.60
27 INT8540 Gene_expression of Serpina1a 5 0.66 3.99 0.34 77.60
28 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 73.68
29 INT73626 Positive_regulation of Gene_expression of PPARG 22 0.70 18.82 4.4 70.68
30 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 65.44
31 INT16323 Gene_expression of pr 62 0.66 36.14 38.26 64.00
32 INT104005 Negative_regulation of Gene_expression of DES 6 0.42 4.82 0.37 60.32
33 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 59.20
34 INT69264 Gene_expression of KIT 207 0.78 179.41 8.95 59.20
35 INT10889 Gene_expression of F8 60 0.78 41.36 5.06 59.20
36 INT68269 Gene_expression of CD99 49 0.77 47.38 3.86 59.20
37 INT1624 Gene_expression of Cea 212 0.76 180.44 34.21 56.56
38 INT10214 Gene_expression of VIM 153 0.78 115.88 16.29 45.12
39 INT39000 Regulation of pr 24 0.44 12.51 4.36 40.00
40 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 35.96
41 INT22943 Positive_regulation of Positive_regulation of Gpt 23 0.47 16.09 5.55 35.96
42 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 35.20
43 INT35103 Positive_regulation of Positive_regulation of SLC17A5 5 0.12 7.51 1.25 35.20
44 INT17739 Gene_expression of S100B 226 0.78 132.7 26.4 35.04
45 INT71644 Gene_expression of MLANA 16 0.75 11.55 1.82 34.36
46 INT106097 Localization of pr 20 0.62 12.01 19.46 32.68
47 INT17049 Localization of CD4 57 0.75 35.33 6.89 30.24
48 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 29.24
49 INT336960 Localization of SPN 1 0.49 0.91 0.04 28.64
50 INT28083 Negative_regulation of Gene_expression of VIM 9 0.41 7.23 1.17 27.52
51 INT70897 Positive_regulation of Gene_expression of PDGFB 15 0.57 13.04 3.52 24.28
52 INT70896 Gene_expression of PDGFB 48 0.65 33.55 8.39 23.32
53 INT83295 Positive_regulation of Cd68 21 0.39 14.55 2.46 16.72
54 INT4756 Positive_regulation of Nrtim1 37 0.33 14.6 24.12 7.12
55 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
56 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
57 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
58 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
59 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 5.00
60 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
61 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
62 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
63 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
64 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 5.00
65 INT9236 Regulation of Gene_expression of TNF 204 0.62 162.66 72.99 5.00
66 INT8347 Gene_expression of SST 181 0.78 104.59 65.45 5.00
67 INT22112 Positive_regulation of Localization of TNF 164 0.70 115.66 52.18 5.00
68 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
69 INT103094 Binding of PPARA 308 0.47 177.26 34.75 5.00
70 INT129686 Gene_expression of FSCN1 46 0.15 18.91 34.47 5.00
71 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 5.00
72 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 5.00
73 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 5.00
74 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
75 INT3400 Positive_regulation of pr 57 0.68 36.9 16.24 5.00
76 INT12087 Regulation of Localization of TNF 44 0.62 28.71 15.17 5.00
77 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 5.00
78 INT103096 Regulation of PPARA 113 0.60 62.47 14.57 5.00
79 INT46619 Gene_expression of CSF1 80 0.73 36.63 12.94 5.00
80 INT111476 Gene_expression of TP63 88 0.76 61.08 11.64 5.00
81 INT2491 Regulation of Cea 38 0.61 26.18 10.95 5.00
82 INT173159 Localization of PPARA 96 0.74 64.55 10.26 5.00
83 INT64346 Positive_regulation of S100B 95 0.70 63.11 9.17 5.00
84 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 5.00
85 INT4991 Positive_regulation of Vim 74 0.69 69.84 8.33 5.00
86 INT36798 Gene_expression of Mki67 178 0.77 132 8.24 5.00
87 INT86867 Regulation of CREB1 15 0.46 4.95 7.28 5.00
88 INT172084 Positive_regulation of Binding of TNF 21 0.50 15.31 6.06 5.00
89 INT181194 Regulation of Gene_expression of PPARA 31 0.44 21.27 5.96 5.00
90 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68 5.00
91 INT49805 Positive_regulation of MUC1 56 0.70 44.5 4.56 5.00
92 INT79692 Negative_regulation of PPARG 24 0.59 16 4.31 5.00
93 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17 5.00
94 INT17182 Binding of Cea 25 0.48 14.98 4.16 5.00
95 INT111477 Gene_expression of KRT7 90 0.74 86.76 4.07 5.00
96 INT172173 Protein_catabolism of TNF 16 0.96 9.95 3.79 5.00
97 INT46621 Positive_regulation of Gene_expression of CSF1 17 0.47 10.53 3.59 5.00
98 INT95652 Gene_expression of Krt20 54 0.61 53.69 3.31 5.00
99 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 5.00
100 INT51607 Positive_regulation of DES 33 0.67 32.24 3.29 5.00
101 INT67379 Positive_regulation of Cd34 38 0.58 26.18 3.28 5.00
102 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19 5.00
103 INT91173 Gene_expression of Pdgfrb 33 0.65 32.55 3.09 5.00
104 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 5.00
105 INT99187 Negative_regulation of Positive_regulation of PPARG 5 0.42 5.07 2.99 5.00
106 INT11775 Gene_expression of Ema 39 0.65 38.12 2.99 5.00
107 INT222961 Negative_regulation of Binding of PPARA 22 0.41 10.76 2.72 5.00
108 INT77925 Negative_regulation of TEP1 21 0.53 15.23 2.62 5.00
109 INT68091 Localization of COL1A1 19 0.66 9.13 2.56 5.00
110 INT137908 Phosphorylation of Pdgfrb 14 0.81 8.44 2.45 5.00
111 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45 5.00
112 INT59784 Binding of DES 22 0.47 19.48 2.27 5.00
113 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26 5.00
114 INT5844 Positive_regulation of Gene_expression of Vim 14 0.25 9.64 2.18 5.00
115 INT109327 Negative_regulation of KIT 42 0.57 43.2 2.15 5.00
116 INT144020 Positive_regulation of Pdgfrb 30 0.69 24.8 1.92 5.00
117 INT58563 Negative_regulation of S100B 13 0.51 11.75 1.77 5.00
118 INT95636 Gene_expression of ACTG2 23 0.44 19.87 1.75 5.00
119 INT104524 Localization of FSCN1 3 0.13 1.76 1.75 5.00
120 INT79691 Regulation of Gene_expression of PPARG 10 0.50 10.44 1.62 5.00
121 INT113985 Positive_regulation of TP63 9 0.50 8.79 1.62 5.00
122 INT193823 Positive_regulation of Gene_expression of TP63 7 0.18 7.74 1.57 5.00
123 INT79690 Negative_regulation of Gene_expression of PPARG 10 0.59 10.48 1.55 5.00
124 INT151450 Positive_regulation of Gene_expression of Kit 23 0.69 13.11 1.43 5.00
125 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36 5.00
126 INT144019 Negative_regulation of Pdgfrb 21 0.58 14.93 1.26 5.00
127 INT104777 Regulation of DES 4 0.38 2.38 1.2 5.00
128 INT237247 Regulation of Mri1 6 0.27 4.64 1.2 5.00
129 INT62496 Binding of CSF1 6 0.36 4.55 1.14 5.00
130 INT166261 Localization of SLN 2 0.66 1.23 1.07 5.00
131 INT79689 Regulation of PPARG 10 0.62 8.04 1.07 5.00
132 INT86834 Positive_regulation of Tg 10 0.69 4.9 1.04 5.00
133 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
134 INT263912 Positive_regulation of SLN 6 0.39 0.66 0.99 5.00
135 INT99289 Localization of STS 8 0.79 6.5 0.92 5.00
136 INT107714 Localization of PPARG 4 0.73 0.88 0.91 5.00
137 INT116314 Gene_expression of Myod1 38 0.70 16.6 0.89 5.00
138 INT125244 Gene_expression of Ril2 4 0.30 1.9 0.87 5.00
139 INT96188 Binding of Cd34 11 0.31 10.4 0.82 5.00
140 INT56955 Binding of MYOG 5 0.27 2.92 0.73 5.00
141 INT164756 Negative_regulation of PDGFRB 32 0.57 21.69 0.72 5.00
142 INT61910 Binding of Slc3a2 6 0.01 3 0.7 5.00
143 INT246036 Positive_regulation of GRN 3 0.17 2.04 0.69 5.00
144 INT89520 Regulation of COL1A1 8 0.32 3.21 0.66 5.00
145 INT276227 Gene_expression of UBL4A 9 0.20 7.12 0.64 5.00
146 INT80025 Positive_regulation of MIB1 5 0.40 5.41 0.64 5.00
147 INT160961 Gene_expression of Fth1 4 0.28 3.89 0.63 5.00
148 INT214707 Gene_expression of Slc2a8 5 0.24 2.76 0.61 5.00
149 INT277699 Gene_expression of Pdgfb 5 0.20 4.84 0.59 5.00
150 INT183979 Localization of PSIP1 2 0.73 1.37 0.59 5.00
151 INT29441 Negative_regulation of Gene_expression of Cea 6 0.20 5.97 0.55 5.00
152 INT144024 Negative_regulation of Phosphorylation of Pdgfrb 6 0.42 3.48 0.51 5.00
153 INT131931 Binding of KRT7 13 0.36 19.24 0.5 5.00
154 INT263904 Negative_regulation of Gene_expression of SLN 1 0.14 7.18 0.47 5.00
155 INT97446 Localization of Mki67 9 0.46 3.74 0.46 5.00
156 INT47311 Gene_expression of Sts 12 0.58 11.02 0.44 5.00
157 INT192342 Phosphorylation of PDGFRB 11 0.80 1.68 0.43 5.00
158 INT88005 Binding of MYOD1 6 0.30 2.08 0.42 5.00
159 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
160 INT147796 Gene_expression of Ccndbp1 5 0.05 3.9 0.4 5.00
161 INT207069 Localization of Fth1 2 0.31 1.94 0.33 5.00
162 INT88070 Binding of Ema 7 0.18 7.39 0.31 5.00
163 INT158766 Localization of GRN 2 0.73 1.59 0.28 5.00
164 INT144021 Binding of Pdgfrb 9 0.37 5.53 0.28 5.00
165 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 5.00
166 INT276224 Binding of Nrtim1 1 0.01 1.3 0.23 5.00
167 INT277701 Localization of Pdgfb 3 0.23 1.49 0.22 5.00
168 INT89370 Gene_expression of Clta 4 0.51 4.22 0.22 5.00
169 INT44872 Localization of Sts 5 0.64 5.2 0.2 5.00
170 INT263884 Gene_expression of Slc2a3 2 0.18 0.86 0.19 5.00
171 INT20214 Localization of Slc3a2 5 0.14 4.91 0.16 5.00
172 INT145147 Negative_regulation of Gene_expression of TP63 4 0.42 2.91 0.15 5.00
173 INT263871 Negative_regulation of Car9 1 0.07 0.54 0.12 5.00
174 INT263908 Positive_regulation of Gene_expression of SLN 1 0.16 1.4 0.12 5.00
175 INT263872 Localization of Adra1d 1 0.01 2.5 0.11 5.00
176 INT98920 Localization of CREB1 4 0.52 1.77 0.1 5.00
177 INT259193 Positive_regulation of Fth1 2 0.14 1.75 0.09 5.00
178 INT192338 Positive_regulation of Phosphorylation of PDGFRB 4 0.45 0.48 0.07 5.00
179 INT277162 Positive_regulation of Binding of Pdgfrb 1 0.06 1.1 0.07 5.00
180 INT263878 Positive_regulation of Rigs1 1 0.05 2.57 0.07 5.00
181 INT229652 Regulation of Myog 2 0.25 0.88 0.06 5.00
182 INT143945 Localization of EWSR1 5 0.78 3.39 0.06 5.00
183 INT277702 Positive_regulation of Gene_expression of Pdgfb 2 0.10 0.55 0.05 5.00
184 INT208648 Positive_regulation of NCBP2 1 0.10 1.39 0.05 5.00
185 INT229654 Positive_regulation of Gene_expression of Cd34 2 0.45 1.19 0.05 5.00
186 INT214703 Positive_regulation of Gene_expression of Slc2a8 2 0.09 1.4 0.05 5.00
187 INT263879 Positive_regulation of Adra1d 1 0.00 0.47 0.04 5.00
188 INT263873 Positive_regulation of Gene_expression of Rigs1 1 0.05 1.27 0.03 5.00
189 INT263877 Gene_expression of Rigs1 1 0.08 11.58 0.03 5.00
190 INT201549 Regulation of CD99 3 0.23 3.6 0.03 5.00
191 INT263911 Localization of TMED7-TICAM2 1 0.01 1.02 0 5.00
192 INT263906 Gene_expression of TMED7-TICAM2 1 0.01 2.8 0 5.00
193 INT204924 Negative_regulation of Clta 1 0.01 1.37 0 5.00
194 INT322420 Binding of FEV 1 0.18 0.29 0 5.00
195 INT263874 Regulation of Rigs1 1 0.03 1.36 0 5.00
196 INT277700 Binding of Pdgfb 1 0.09 0.67 0 5.00
197 INT263914 Binding of TMED7-TICAM2 1 0.01 1.56 0 5.00
198 INT322422 Localization of FEV 1 0.40 0.82 0 5.00
199 INT193821 Positive_regulation of Gene_expression of pr 3 0.24 2.8 0 5.00
200 INT193822 Regulation of Gene_expression of Sts 1 0.03 1.04 0 5.00
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