D:Disorder Of Lipid Metabolism

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Latest revision as of 20:15, 6 October 2012

pChart

Disease Term
Synonyms A Lipoproteins, ALPHA LIPOPROTEINS, ANDERSONS DISEASE, Apolipoprotein, B Lipoproteins, Beta Lipoproteins, Cholesteryl Ester Storage Disease, Chylomicron Retention Disease, Chylomicrons, Circulating Adiponectin Qtl, CPT DEFICIENCY
Documents 2877
Hot Single Events 200
Hot Interactions 200

[edit] Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Disorder Of Lipid Metabolism. They are ordered first by their relevance to Disorder Of Lipid Metabolism and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT208354 Binding of Apoe and Hdl1 12 0.13 8.37 0.77 100.00
2 INT290194 Binding of PLTP and Hdl1 1 0.07 7.3 0.13 100.00
3 INT239341 Binding of Abca1 and Hdl1 1 0.04 4.78 0 100.00
4 INT213026 Hdl1 Positive_regulation of Nos3 5 0.16 7.92 0.73 100.00
5 INT247439 Binding of APOA1 and HSD11B1 3 0.32 5.01 0.03 100.00
6 INT170212 Gene_expression of PLTP Positive_regulation of HSD11B1 1 0.12 3.01 0 100.00
7 INT213005 Hdl1 Positive_regulation of Akt1 3 0.19 3.81 0.14 100.00
8 INT208353 Binding of Apoc4 and Apoc3 1 0.00 2.56 0.04 100.00
9 INT239348 Binding of Apoa1 and Hdl1 1 0.03 3.34 0.05 100.00
10 INT239349 Hdl1 Negative_regulation of Tbxa2r 1 0.03 3.37 0 100.00
11 INT208362 Binding of Apoc4 and Hdl1 1 0.00 2.4 0.08 100.00
12 INT300197 Binding of APOA1 and C1S 1 0.39 3.56 0 100.00
13 INT344716 Binding of Hdl1 and Chdh 1 0.03 3.24 0 100.00
14 INT213046 Hdl1 Negative_regulation of Gene_expression of tf 1 0.07 2.36 0 100.00
15 INT213048 Cog1 Positive_regulation of Localization of tf 1 0.03 2.38 0 100.00
16 INT213020 Cd320 Positive_regulation of Localization of tf 1 0.16 2.36 0 100.00
17 INT213023 Hdl1 Regulation of Nos3 2 0.09 4.06 0.09 100.00
18 INT170210 Binding of CETP and HSD11B1 1 0.17 2.58 0 100.00
19 INT326067 APOA1 Positive_regulation of Localization of APOE 1 0.61 4.22 0.07 100.00
20 INT213001 Hdl1 Positive_regulation of Trib3 1 0.00 2 0.06 100.00
21 INT239317 Egfl7 Positive_regulation of Hdl1 2 0.01 2.3 0.14 100.00
22 INT326997 HSD11B1 Negative_regulation of Hdl2 1 0.12 2.06 0 100.00
23 INT326980 HSD11B1 Negative_regulation of JPH3 1 0.03 2.05 0 100.00
24 INT300039 Binding of HSD11B1 and OLR1 1 0.01 1.56 0 100.00
25 INT300040 Binding of DBP and OLR1 1 0.02 1.56 0 100.00
26 INT213051 Hdl1 Positive_regulation of Pik3r1 1 0.13 1.93 0.09 100.00
27 INT239337 Abca1 Positive_regulation of RCT 1 0.07 3.11 0.24 100.00
28 INT300196 Binding of HSD11B1 and CHDH 1 0.07 4.01 0 100.00
29 INT353062 HSD11B1 Regulation of Gene_expression of ADIPOQ 1 0.13 5.03 0 100.00
30 INT353061 HSD11B1 Regulation of Gene_expression of LEP 1 0.20 5.03 0 100.00
31 INT170213 CETP Positive_regulation of Gene_expression of HSD11B1 1 0.21 1.49 0 100.00
32 INT170211 Binding of HSD11B1 and LPL 1 0.02 1.47 0 100.00
33 INT213149 DAK Regulation of HSD11B1 1 0.00 1.42 0 100.00
34 INT344709 Niacr1 Positive_regulation of Hdl1 1 0.32 2.74 0.46 100.00
35 INT208350 Positive_regulation of Hdl1 Positive_regulation of Apoe 1 0.12 1.27 0.04 100.00
36 INT208357 Hdl1 Positive_regulation of Localization of Apoe 1 0.12 1.26 0.04 100.00
37 INT208356 Hdl1 Positive_regulation of Apoe 1 0.12 1.25 0.04 100.00
38 INT239318 Binding of Cor and Hdl1 1 0.07 1.69 0.05 100.00
39 INT208361 Positive_regulation of Binding of Apoe and Hdl1 1 0.12 1.22 0.1 100.00
40 INT239352 Binding of C1S and Hdl1 1 0.06 1.73 0 100.00
41 INT170215 CETP Positive_regulation of HSD11B1 1 0.26 1.35 0 100.00
42 INT170214 PLTP Positive_regulation of HSD11B1 1 0.11 1.34 0 100.00
43 INT239322 Hdl1 Positive_regulation of RCT 1 0.02 2.16 0.03 100.00
44 INT265955 Clas4 Regulation of Negative_regulation of HSD11B1 1 0.00 1.14 0 100.00
45 INT240619 Binding of CRP and ADIPOQ 8 0.18 10.74 0.78 100.00
46 INT208365 Apoc3 Positive_regulation of Localization of PROC 1 0.00 1.13 0 100.00
47 INT208364 Hdl1 Positive_regulation of Localization of PROC 1 0.00 1.13 0 100.00
48 INT300194 HSD11B1 Negative_regulation of CHDH 1 0.08 2.19 0 100.00
49 INT335054 LPL Positive_regulation of Localization of VLDLR 1 0.04 1.48 0.67 100.00
50 INT312792 Binding of Pon1 and Hdl1 1 0.04 1.85 0.11 100.00
51 INT344722 Binding of Lig3 and Chdh 1 0.00 1.48 0 100.00
52 INT213007 Hdl1 Regulation of Regulation of Apc 1 0.08 1.24 0 100.00
53 INT213054 Hdl1 Regulation of Apc 1 0.05 1.24 0 100.00
54 INT213034 Hdl1 Positive_regulation of Apc 1 0.08 1.21 0 100.00
55 INT213056 Hdl1 Positive_regulation of Vtn Positive_regulation of Apc 1 0.00 1.21 0 100.00
56 INT213058 Binding of Apoa1 and Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.05 1.15 0.12 100.00
57 INT213009 Hdl1 Positive_regulation of Positive_regulation of Apc 1 0.09 1.14 0 100.00
58 INT352793 Binding of APOC1 and FGF21 1 0.01 2.76 0 100.00
59 INT213052 Hdl1 Negative_regulation of Gene_expression of Vwf 1 0.19 1.23 0.04 100.00
60 INT213038 Hdl1 Positive_regulation of Localization of tf 1 0.12 1.11 0 100.00
61 INT213060 Hdl1 Negative_regulation of Gene_expression of PLEK 1 0.25 1.33 0.05 100.00
62 INT301906 Binding of HMOX1 and HSD11B1 1 0.05 2.41 0 100.00
63 INT239321 Binding of Abca1 and Apoa1 1 0.11 1.61 0 100.00
64 INT290181 Binding of APOE and PLTP 1 0.17 1.61 0.04 100.00
65 INT247438 Binding of APOB and SACM1L 1 0.28 2 0 100.00
66 INT212938 Binding of Scarb1 and Hdl1 Positive_regulation of Trib3 1 0.00 1.02 0.03 100.00
67 INT213037 Hdl1 Positive_regulation of Gene_expression of Serpine1 1 0.19 1.19 0.04 100.00
68 INT239327 Positive_regulation of Binding of Lcat and Hdl1 1 0.06 1.52 0.06 100.00
69 INT239326 Binding of Lcat and Hdl1 1 0.05 1.52 0.06 100.00
70 INT213057 Hdl1 Positive_regulation of Binding of Scarb1 and Hdl1 1 0.08 0.96 0.03 100.00
71 INT197725 Negative_regulation of CETP Positive_regulation of Positive_regulation of HSD11B1 1 0.11 1.15 0 100.00
72 INT213011 Binding of Scarb1 and Hdl1 1 0.13 0.96 0.03 100.00
73 INT297560 Binding of HSD11B1 and APOL1 1 0.04 0.88 0 100.00
74 INT344707 Scarb1 Positive_regulation of Positive_regulation of Hdl1 1 0.14 0.88 0.14 100.00
75 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 100.00
76 INT344710 Lipc Positive_regulation of Positive_regulation of Hdl1 1 0.04 0.87 0.14 100.00
77 INT144551 Binding of Lrp8 and Sepp1 1 0.55 1.73 0.93 100.00
78 INT170237 Lpl Regulation of CETP 1 0.02 0.99 0 100.00
79 INT170236 Lpl Regulation of HSD11B1 1 0.04 0.98 0 100.00
80 INT344703 Hdl1 Negative_regulation of Gene_expression of Serpine1 1 0.07 1.26 0.05 100.00
81 INT213047 Hdl1 Positive_regulation of Gene_expression of Nos3 1 0.14 0.94 0.04 100.00
82 INT344719 Hdl1 Positive_regulation of Plat 1 0.10 1.23 0.05 100.00
83 INT239328 Hdl1 Regulation of Gene_expression of Kitl 1 0.08 1.86 0.2 100.00
84 INT213049 Hdl1 Regulation of Gene_expression of Nppc 1 0.09 1 0 100.00
85 INT213053 Hdl1 Negative_regulation of Gene_expression of Adamts1 1 0.07 0.88 0.1 100.00
86 INT267974 APOB Negative_regulation of HSD11B1 1 0.01 0.75 0 100.00
87 INT344721 Binding of AHA and Hdl1 1 0.02 1.16 0.15 100.00
88 INT344720 Niacr1 Negative_regulation of Binding of Hdl1 1 0.17 1.13 0 100.00
89 INT265954 Regulation of Binding of HSD11B1 and Clas4 1 0.00 0.87 0 100.00
90 INT265953 Binding of HSD11B1 and Clas4 1 0.00 0.87 0 100.00
91 INT213019 Hdl1 Positive_regulation of Tgoln1 1 0.03 1.01 0.07 100.00
92 INT186191 Binding of SCARB1 and TBP 1 0.03 2.57 0.24 100.00
93 INT344708 Hdl1 Positive_regulation of Gene_expression of Plat 1 0.08 1.26 0 100.00
94 INT247442 Binding of HSD11B1 and SNRNP70 2 0.04 1.3 0 100.00
95 INT213059 Hdl1 Regulation of BGN 1 0.16 0.79 0.03 100.00
96 INT213050 Hdl1 Regulation of Bgn 1 0.00 0.79 0.03 100.00
97 INT239330 Positive_regulation of Ppara Positive_regulation of Hdl1 1 0.05 1.17 0.03 100.00
98 INT213036 Hdl1 Positive_regulation of Phosphorylation of Mapk14 1 0.22 0.78 0.03 100.00
99 INT213039 Hdl1 Positive_regulation of Prkca 1 0.10 0.98 0.03 100.00
100 INT213004 Hdl1 Positive_regulation of Mapk14 1 0.22 0.97 0.03 100.00
101 INT213030 Hdl1 Regulation of Gene_expression of Edn1 1 0.06 0.88 0 100.00
102 INT213016 Regulation of Hdl1 Positive_regulation of Pik3r1 1 0.09 0.97 0.05 100.00
103 INT213014 Regulation of Hdl1 Positive_regulation of Akt1 1 0.12 0.97 0.05 100.00
104 INT300191 Binding of C1S and HSD11B1 1 0.13 1.75 0 100.00
105 INT326086 Binding of HSD11B1 and Abo 1 0.00 0.89 0 100.00
106 INT300198 Positive_regulation of Binding of C1S and CHDH 1 0.31 1.63 0 100.00
107 INT326061 Binding of HSD11B1 and LCAT 1 0.11 0.89 0 100.00
108 INT344704 Positive_regulation of Ppara Positive_regulation of Binding of Hdl1 1 0.13 0.83 0.28 100.00
109 INT344715 Positive_regulation of Ppara Positive_regulation of Gene_expression of Pltp 1 0.02 0.83 0.28 100.00
110 INT213018 Hdl1 Negative_regulation of Gene_expression of Mmp9 1 0.10 0.81 0.09 100.00
111 INT213008 Hdl1 Positive_regulation of Gene_expression of Edn1 1 0.10 0.85 0 100.00
112 INT290193 Binding of APOA1 and Hdl1 1 0.01 1 0 100.00
113 INT79523 Binding of HSD11B1 and C9orf3 1 0.52 1.12 0.06 100.00
114 INT302584 Binding of Lpl and Apoa5 1 0.20 0.63 0 100.00
115 INT302594 Binding of CETP and Apoa5 1 0.26 0.63 0 100.00
116 INT302586 Binding of Lipc and Apoa5 1 0.26 0.63 0 100.00
117 INT213146 TIMP1 Regulation of HSD11B1 1 0.02 0.7 0 100.00
118 INT239333 Abcg1 Positive_regulation of RCT 1 0.06 1.29 0.03 100.00
119 INT155644 Binding of CAV1 and HSD11B1 1 0.39 0.77 0.15 100.00
120 INT231395 Binding of HSD11B1 and Apob 1 0.27 1.18 0.04 100.00
121 INT306922 Negative_regulation of Ephx2 Positive_regulation of Hdl1 1 0.05 1.06 0 100.00
122 INT247435 Binding of APOB and SNRNP70 1 0.04 2.2 0 100.00
123 INT213041 Hdl1 Negative_regulation of Gene_expression of Vcam1 1 0.14 0.9 0.17 100.00
124 INT265952 Clas4 Regulation of Negative_regulation of CRP 1 0.01 0.57 0 100.00
125 INT265951 Clas4 Negative_regulation of CRP 1 0.01 0.57 0 100.00
126 INT239339 Hdl1 Negative_regulation of Gene_expression of Paf 1 0.02 1.43 0.13 100.00
127 INT317842 Hdlcl1 Positive_regulation of Ldlr 1 0.00 1.11 0 100.00
128 INT312769 Binding of Apoe and Pon1 1 0.04 0.86 0 100.00
129 INT312794 Hdl1 Regulation of Pon1 1 0.02 1.63 0.15 100.00
130 INT260563 Hdl1 Positive_regulation of Positive_regulation of Nos3 1 0.05 1.55 0 100.00
131 INT253945 Adrm1 Negative_regulation of Hdl1 1 0.00 1.18 0 100.00
132 INT247440 Binding of APOA1 and APOB 1 0.28 1.02 0 100.00
133 INT343353 Binding of HSD11B1 and Egfl7 1 0.03 0.97 0 100.00
134 INT288853 Binding of HSD11B1 and LDLR 1 0.26 1.52 0.04 100.00
135 INT156531 Binding of ABCA1 and HSD11B1 1 0.22 1.06 0.14 100.00
136 INT134494 Binding of APOE and Alb 1 0.11 0.45 0.2 100.00
137 INT344717 Binding of Niacr1 and Hdl1 1 0.17 1.51 0 100.00
138 INT194482 Binding of Rare1 and Hdl1 1 0.00 1.73 0 100.00
139 INT297563 Binding of HSD11B1 and TBPL1 1 0.01 0.41 0 100.00
140 INT247437 Binding of HSD11B1 and SACM1L 1 0.01 0.98 0 100.00
141 INT325025 Apoa2 Positive_regulation of Hdl1 1 0.05 1.03 0.04 100.00
142 INT213010 Hdl1 Negative_regulation of Gene_expression of Icam1 1 0.15 1.01 0.15 100.00
143 INT342584 Binding of HSD11B1 and Shbg 1 0.02 0.72 0 100.00
144 INT281005 Hdlcl1 Regulation of OTOR 1 0.00 1.62 0.26 100.00
145 INT270759 Binding of HSD11B1 and TERT 1 0.07 1.67 0 100.00
146 INT270043 Binding of Ldlr and Hdl1 1 0.01 2.3 0.43 100.00
147 INT197726 Negative_regulation of CETP Positive_regulation of HSD11B1 1 0.11 0.76 0 100.00
148 INT251965 Binding of HSD11B1 and FADS1 1 0.16 0.37 0 100.00
149 INT240626 Binding of ADIPOQ and Hdlcl1 1 0.02 3.27 0.28 100.00
150 INT265848 Binding of HSD11B1 and Cand1 1 0.40 0.85 0 100.00
151 INT329085 Csf2 Positive_regulation of Apoe 1 0.00 1.23 0.42 100.00
152 INT355671 Binding of Saa and Hdlcl1 1 0.00 0.79 0.11 100.00
153 INT297335 Binding of Apoc3 and Hdl1 1 0.00 0.92 0.29 100.00
154 INT240617 Binding of APOB and ADIPOQ 1 0.04 3.62 0.38 100.00
155 INT353861 Binding of Mgp and Phdlc1 1 0.01 5.09 0.16 100.00
156 INT251962 Binding of HSD11B1 and RS1 1 0.00 0.33 0 100.00
157 INT325027 Apoc3 Negative_regulation of Pnlip 1 0.01 1.02 0.04 100.00
158 INT312793 Binding of Hdl1 and Pon3 1 0.00 0.84 0.14 100.00
159 INT325026 Apoc3 Negative_regulation of Lpl 1 0.03 1.01 0.04 100.00
160 INT262994 Binding of CRP and HSD11B1 1 0.15 3.02 0.03 100.00
161 INT149791 Binding of Lrp8 and Reln 4 0.36 0.38 0.22 100.00
162 INT141635 Binding of APOB and Alb 1 0.02 0.3 0.26 100.00
163 INT141634 Binding of Alb and Nrg1 1 0.00 0.3 0.26 100.00
164 INT350254 Slc12a6 Regulation of Gene_expression of Adipoq 1 0.02 0.63 0 100.00
165 INT278184 Binding of Crp and Hdlcl1 1 0.01 2.72 0.09 100.00
166 INT296023 Positive_regulation of Apoa2 Negative_regulation of APOA1 1 0.50 0.35 0.05 100.00
167 INT352794 Binding of APOB and FGF21 1 0.01 1.98 0 100.00
168 INT270206 Hdl1 Positive_regulation of Gene_expression of IL2 1 0.01 0.35 0.03 100.00
169 INT296025 Apoa2 Negative_regulation of APOA1 1 0.47 0.35 0.05 100.00
170 INT186185 Binding of SCARB1 and SCARB2 1 0.22 0.58 0.05 100.00
171 INT186192 Binding of SCARB2 and TBP 1 0.02 0.58 0.05 100.00
172 INT296024 Apoa2 Negative_regulation of CETP 1 0.39 0.35 0.05 100.00
173 INT239332 Hdl1 Positive_regulation of Gene_expression of Apoa1 1 0.04 0.84 0 100.00
174 INT239343 Hdl1 Positive_regulation of Gene_expression of Cor 1 0.09 0.84 0 100.00
175 INT342585 Binding of HSD11B1 and Dbp 1 0.05 0.42 0 100.00
176 INT290180 Binding of APOB and PLTP 1 0.19 0.6 0.04 100.00
177 INT190885 Binding of Apoa2 and Hdl1 1 0.02 0.73 0.07 100.00
178 INT323056 LDLR Regulation of HSD11B1 1 0.01 1.2 0.05 100.00
179 INT229291 BAS Positive_regulation of HSD11B1 1 0.09 0.22 0.06 100.00
180 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0 100.00
181 INT122049 Binding of HSD11B1 and Lcat 1 0.21 0.83 0.31 100.00
182 INT240625 Binding of CRP and Hdlcl1 1 0.01 2.56 0.19 100.00
183 INT262997 Binding of HSD11B1 and ADIPOQ 1 0.54 2.82 0.07 100.00
184 INT284091 VWF Negative_regulation of PON2 1 0.41 2.32 0 100.00
185 INT284090 VWF Negative_regulation of SERPINA1 1 0.04 2.34 0 100.00
186 INT284093 VWF Negative_regulation of APOE 1 0.40 2.32 0 100.00
187 INT229986 Binding of CAMK4 and HSD11B1 1 0.01 1 0.1 100.00
188 INT341018 Lrp8 Positive_regulation of Phosphorylation of DAB1 1 0.02 0.2 0.09 100.00
189 INT240623 Binding of CRP and Apob 1 0.01 0.52 0.04 100.00
190 INT73794 Binding of HSD11B1 and Igfbp1 1 0.06 1.15 0.07 100.00
191 INT128986 Binding of CST3 and Phdlc1 1 0.01 1.96 0.22 100.00
192 INT273893 ARSA Positive_regulation of HSD11B1 1 0.00 0.61 0.4 100.00
193 INT251963 Binding of HSD11B1 and LIPC 1 0.15 0.35 0.03 100.00
194 INT122529 Apoe Regulation of S100B 1 0.18 0.29 0.16 100.00
195 INT122528 Apoe Regulation of Eno2 1 0.05 0.29 0.16 100.00
196 INT155388 Binding of LPA and Lipg 1 0.00 1.22 0.12 100.00
197 INT288908 Apoa1 Positive_regulation of Gene_expression of HSD11B1 1 0.03 0.53 0.04 100.00
198 INT155387 Binding of LPA and RT1-A 1 0.00 1.22 0.12 100.00
199 INT50079 Binding of NPPA and SLC12A1 1 0.01 0.42 0.07 100.00
200 INT50078 Binding of APOE and NPPA 1 0.30 0.42 0.07 100.00

[edit] Single Events

The table below shows the top 200 pain related interactions that have been reported for Disorder Of Lipid Metabolism. They are ordered first by their pain relevance and then by number of times they were reported in Disorder Of Lipid Metabolism. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8640 Positive_regulation of HSD11B1 332 0.67 377.84 22.36 100.00
2 INT1735 Gene_expression of HSD11B1 199 0.75 257.87 11.5 100.00
3 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 100.00
4 INT31582 Gene_expression of Hdl1 103 0.66 118.95 6.42 100.00
5 INT17086 Binding of HSD11B1 84 0.47 122.28 6.16 100.00
6 INT1734 Negative_regulation of HSD11B1 116 0.57 125.13 10.52 100.00
7 INT17913 Regulation of HSD11B1 87 0.60 93.23 6.04 100.00
8 INT17686 Negative_regulation of Hdl1 72 0.36 81.85 7.74 100.00
9 INT1631 Binding of Hdl1 42 0.36 49.22 2.92 100.00
10 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 100.00
11 INT34585 Negative_regulation of Positive_regulation of HSD11B1 31 0.57 43.54 2.47 100.00
12 INT72676 Gene_expression of APOA1 34 0.75 34.15 1.67 100.00
13 INT41986 Positive_regulation of Gene_expression of HSD11B1 26 0.49 32.84 1.52 100.00
14 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 100.00
15 INT28060 Positive_regulation of Hdlcl1 48 0.66 37.31 3.79 100.00
16 INT28673 Gene_expression of APOB 51 0.73 34.02 3.95 100.00
17 INT208334 Localization of Hdl1 22 0.54 18.94 0.74 100.00
18 INT170229 Gene_expression of PLTP 9 0.77 21.32 0.24 100.00
19 INT197493 Localization of Apoe 61 0.79 27.48 7.06 100.00
20 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 100.00
21 INT181880 Positive_regulation of Apoa1 19 0.66 21.19 2.43 100.00
22 INT24643 Gene_expression of Hdlcl1 30 0.73 26.83 1.9 100.00
23 INT116725 Positive_regulation of CETP 19 0.49 16.33 0.36 100.00
24 INT9649 Positive_regulation of LPA 105 0.69 74.75 13.89 100.00
25 INT8667 Localization of HSD11B1 22 0.73 22.74 1.25 100.00
26 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 100.00
27 INT40877 Positive_regulation of APOB 35 0.68 32.47 1.86 100.00
28 INT550 Negative_regulation of LDLR 66 0.43 44.71 3.04 100.00
29 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 100.00
30 INT21712 Positive_regulation of APOA1 32 0.67 21.64 2.64 100.00
31 INT9650 Gene_expression of LPA 141 0.75 104.57 29 100.00
32 INT87517 Gene_expression of LDLR 73 0.69 37.35 3.32 100.00
33 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 100.00
34 INT17813 Positive_regulation of Hdl2 11 0.36 12.23 1.04 100.00
35 INT39390 Negative_regulation of Hdl2 8 0.43 9.83 0.35 100.00
36 INT19967 Gene_expression of C9orf3 18 0.75 26.51 4.6 100.00
37 INT11957 Negative_regulation of LPA 52 0.59 39.09 6.84 100.00
38 INT181881 Positive_regulation of Gene_expression of Apoa1 13 0.48 14.31 1.45 100.00
39 INT239303 Positive_regulation of Gene_expression of Hdl1 8 0.36 12.46 0.53 100.00
40 INT15772 Negative_regulation of Hdlcl1 17 0.41 15.77 1.45 100.00
41 INT57138 Binding of Hdlcl1 13 0.30 18.51 0.64 100.00
42 INT74614 Positive_regulation of Apoa1 16 0.68 23.95 5.04 100.00
43 INT19966 Positive_regulation of C9orf3 19 0.67 21.88 4.38 100.00
44 INT128609 Gene_expression of C1S 18 0.75 17.36 0.98 100.00
45 INT165620 Negative_regulation of Gene_expression of HSD11B1 10 0.41 14.52 0.45 100.00
46 INT212966 Negative_regulation of Gene_expression of Hdl1 8 0.27 10.98 0.49 100.00
47 INT136754 Gene_expression of SCARB1 64 0.77 43.28 4.82 100.00
48 INT142264 Positive_regulation of Apoe 47 0.50 26.35 6.94 100.00
49 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 100.00
50 INT24644 Regulation of Hdlcl1 18 0.42 15.44 0.91 100.00
51 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
52 INT9466 Binding of APOB 27 0.41 19.36 1.56 100.00
53 INT97710 Localization of Apoe 1 0.79 7.18 3.2 100.00
54 INT10863 Positive_regulation of Ldlr 45 0.68 31.06 7.05 100.00
55 INT89580 Negative_regulation of STAR 16 0.35 14.88 0.2 100.00
56 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 100.00
57 INT15033 Gene_expression of Apoe 18 0.78 14.97 3.75 100.00
58 INT10057 Gene_expression of Ldlr 35 0.67 23.99 3.05 100.00
59 INT189968 Binding of APOA1 12 0.47 10.1 0.3 100.00
60 INT256251 Regulation of Gene_expression of Hdl1 4 0.33 7.35 0.21 100.00
61 INT9832 Gene_expression of Shbg 96 0.75 56.71 12.19 100.00
62 INT23199 Binding of LDLR 22 0.47 17.08 1.16 100.00
63 INT109411 Gene_expression of SAT1 61 0.77 67.99 3.08 100.00
64 INT28486 Positive_regulation of Phdlc1 18 0.40 14.4 2.17 100.00
65 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
66 INT208344 Positive_regulation of Localization of Apoe 22 0.48 9.6 2.27 100.00
67 INT212994 Positive_regulation of Positive_regulation of Hdl1 8 0.36 7.21 0.55 100.00
68 INT229278 Positive_regulation of Cby1 5 0.67 8.07 0.85 100.00
69 INT20238 Regulation of APOB 9 0.61 11.52 1.26 100.00
70 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 100.00
71 INT8579 Gene_expression of Apoa1 13 0.76 35.89 7.21 100.00
72 INT63042 Binding of Apoe 59 0.48 31.23 5.88 100.00
73 INT104624 Negative_regulation of Apoe 26 0.59 19.25 3.71 100.00
74 INT74870 Gene_expression of Apo 17 0.75 12.5 1.38 100.00
75 INT116724 Positive_regulation of Gene_expression of CETP 3 0.41 7.92 0.23 100.00
76 INT229279 Negative_regulation of Cby1 15 0.42 9.4 0.31 100.00
77 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 100.00
78 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85 100.00
79 INT180451 Positive_regulation of Apoa2 15 0.67 12.65 0.89 100.00
80 INT240765 Positive_regulation of Pon1 16 0.67 12.06 0.48 100.00
81 INT9467 Negative_regulation of APOB 14 0.57 10.49 0.88 100.00
82 INT43985 Regulation of LPA 29 0.62 20.79 3.29 100.00
83 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 100.00
84 INT10830 Regulation of Apoa1 11 0.44 15.1 3.04 100.00
85 INT207445 Positive_regulation of PLA2G7 7 0.63 7.66 1 100.00
86 INT10827 Gene_expression of Apob 16 0.78 13.08 0.9 100.00
87 INT50080 Binding of APOE 38 0.45 29.61 2.67 100.00
88 INT11030 Binding of LPA 70 0.48 40.35 4.81 100.00
89 INT8668 Regulation of Positive_regulation of HSD11B1 6 0.44 6.36 0.35 100.00
90 INT57360 Gene_expression of STAR 31 0.66 12.72 2.24 100.00
91 INT183276 Negative_regulation of Adrm1 10 0.04 7.25 1.74 100.00
92 INT267961 Negative_regulation of Apoc1 1 0.01 3.95 0 100.00
93 INT183389 Regulation of Apob 4 0.01 5.17 0.05 100.00
94 INT159425 Positive_regulation of Cd320 11 0.67 9.35 0.11 100.00
95 INT175580 Localization of APOE 10 0.76 18.84 0.65 100.00
96 INT3557 Positive_regulation of C1S 10 0.67 8.73 0.54 100.00
97 INT41984 Regulation of Gene_expression of HSD11B1 4 0.44 4.18 0.23 100.00
98 INT20239 Regulation of APOA1 10 0.60 10.98 0.51 100.00
99 INT10829 Regulation of Ldlr 12 0.34 8.12 1.35 100.00
100 INT57728 Regulation of LDLR 25 0.41 13.18 3.46 100.00
101 INT326991 Negative_regulation of Localization of HSD11B1 1 0.29 3.92 0 100.00
102 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 100.00
103 INT22454 Regulation of Crp 213 0.62 160.67 49.24 100.00
104 INT239305 Negative_regulation of Cand1 1 0.57 4.98 0.04 100.00
105 INT31581 Regulation of Hdl2 3 0.22 4.55 0.28 100.00
106 INT226768 Positive_regulation of Negative_regulation of Hdl1 3 0.29 6.34 0.2 100.00
107 INT181879 Negative_regulation of Apoa1 8 0.55 8.18 1.11 100.00
108 INT37799 Gene_expression of Apob 13 0.56 10.59 1.36 100.00
109 INT15773 Negative_regulation of C9orf3 8 0.57 6.26 1.06 100.00
110 INT37800 Positive_regulation of Apob 7 0.18 11.01 0.48 100.00
111 INT142265 Regulation of Apoe 20 0.60 9.52 2.23 100.00
112 INT52047 Gene_expression of APOE 50 0.78 34.75 3.52 100.00
113 INT100861 Binding of CRP 179 0.48 175.2 26.45 100.00
114 INT23257 Regulation of CRP 127 0.62 100.05 21.87 100.00
115 INT170228 Negative_regulation of PLTP 3 0.43 4.67 0 100.00
116 INT187410 Localization of Cd320 14 0.78 9.03 0.31 100.00
117 INT55758 Positive_regulation of Apoe 15 0.70 11.71 4.69 100.00
118 INT144689 Regulation of RCT 49 0.53 25.91 9.6 100.00
119 INT10828 Regulation of Apob 7 0.39 7.55 0.83 100.00
120 INT28059 Positive_regulation of Apol7b 7 0.03 8.19 0.44 100.00
121 INT187411 Gene_expression of Cd320 23 0.75 12.1 1.39 100.00
122 INT212983 Positive_regulation of Positive_regulation of Nos3 9 0.51 7.08 1.23 100.00
123 INT190883 Gene_expression of Apoc3 16 0.38 14.18 1.93 100.00
124 INT106522 Negative_regulation of Phosphorylation of Akt1 65 0.58 34.44 7.83 100.00
125 INT265946 Regulation of STAR 2 0.04 3.15 0 100.00
126 INT31583 Positive_regulation of Hdl3 6 0.39 5.14 0.92 100.00
127 INT10858 Negative_regulation of Apol7b 3 0.02 5.28 0.33 100.00
128 INT254042 Regulation of Gene_expression of STAR 2 0.10 3.16 0 100.00
129 INT187405 Gene_expression of Cand1 8 0.65 7.25 0.16 100.00
130 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 100.00
131 INT190691 Negative_regulation of APOA1 12 0.42 15.9 0.39 100.00
132 INT122988 Gene_expression of CLU 28 0.75 24.07 1.21 100.00
133 INT72672 Positive_regulation of Gene_expression of APOA1 4 0.67 3.81 0.89 100.00
134 INT64051 Gene_expression of Col4a4 33 0.61 10.1 17.82 100.00
135 INT37556 Negative_regulation of Apo 10 0.14 7.77 1.25 100.00
136 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 100.00
137 INT174753 Gene_expression of Apoa2 15 0.75 13.82 0.41 100.00
138 INT18340 Gene_expression of CRX 16 0.22 13.85 7.13 100.00
139 INT36453 Binding of ABCA1 48 0.45 19.9 10.84 100.00
140 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 100.00
141 INT181888 Regulation of Apoa1 5 0.26 5.07 0.6 100.00
142 INT23191 Gene_expression of HDLCQ1 13 0.60 14.39 1.58 100.00
143 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 100.00
144 INT187665 Negative_regulation of Negative_regulation of HSD11B1 2 0.42 2.82 0 100.00
145 INT22863 Negative_regulation of Apoa1 10 0.57 10.68 1.86 100.00
146 INT34586 Positive_regulation of Negative_regulation of HSD11B1 6 0.49 4.39 1.05 100.00
147 INT22139 Negative_regulation of Phdlc1 7 0.25 5.19 1.06 100.00
148 INT44942 Positive_regulation of Localization of HSD11B1 5 0.49 4.18 0.31 100.00
149 INT173693 Localization of Gopc 249 0.65 70.49 38.81 100.00
150 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 100.00
151 INT224415 Gene_expression of CIMT 28 0.57 12.35 1.15 100.00
152 INT17685 Negative_regulation of Cog1 23 0.42 15.65 3.56 100.00
153 INT38290 Negative_regulation of Hdl3 5 0.43 4.07 0.36 100.00
154 INT34583 Negative_regulation of Positive_regulation of Hdl1 4 0.09 3.51 0.16 100.00
155 INT26975 Gene_expression of Adipoq 113 0.75 106.71 14.46 100.00
156 INT22865 Negative_regulation of HDLCQ1 9 0.44 8.16 1.06 100.00
157 INT97713 Negative_regulation of Apoe 4 0.59 4.57 2.52 100.00
158 INT85647 Transcription of HSD11B1 5 0.67 3.61 0.23 100.00
159 INT212992 Regulation of Positive_regulation of Hdl1 3 0.23 4.64 0.44 100.00
160 INT44325 Positive_regulation of Localization of Ptgis 3 0.03 2.47 0.3 100.00
161 INT208341 Positive_regulation of Localization of Hdl1 1 0.10 1.83 0.03 100.00
162 INT27587 Positive_regulation of STAR 7 0.46 6.37 0.99 100.00
163 INT162141 Localization of CRX 3 0.11 4.24 1.16 100.00
164 INT128412 Positive_regulation of Cand1 5 0.67 3.58 1.1 100.00
165 INT190882 Regulation of Gene_expression of Apoa1 4 0.23 3.67 0.43 100.00
166 INT95131 Binding of Cd4 27 0.37 21.62 5.07 100.00
167 INT39271 Positive_regulation of Gene_expression of Hdlcl1 4 0.48 3.97 0.55 100.00
168 INT312756 Protein_catabolism of Hdl1 2 0.56 2.43 0 100.00
169 INT104221 Regulation of Gene_expression of CRP 30 0.45 20.01 4.07 100.00
170 INT267964 Regulation of Apoc1 1 0.00 1.95 0 100.00
171 INT38299 Negative_regulation of FCGR2C 6 0.21 3.92 0.52 100.00
172 INT129425 Negative_regulation of Ldlr 22 0.42 17.15 0.97 100.00
173 INT287187 Regulation of TBP 3 0.13 2.42 0 100.00
174 INT113960 Positive_regulation of Gene_expression of APOB 8 0.49 5.88 1.39 100.00
175 INT201005 Gene_expression of APOL1 9 0.75 4.66 0.53 100.00
176 INT19964 Negative_regulation of Positive_regulation of C9orf3 3 0.42 4.06 0.67 100.00
177 INT97716 Transcription of Apoe 3 0.53 2.61 1.36 100.00
178 INT5166 Binding of Ldlr 14 0.48 11.95 3.32 100.00
179 INT239411 Localization of APOB 10 0.76 5.71 0.04 100.00
180 INT61972 Negative_regulation of TBP 5 0.32 3.56 0.53 100.00
181 INT72141 Binding of Apoe 11 0.37 10.91 3.27 100.00
182 INT186862 Regulation of Pon1 5 0.60 6.15 0.51 100.00
183 INT267962 Regulation of Gene_expression of Apoc1 1 0.00 1.89 0 100.00
184 INT267960 Gene_expression of Apoc1 1 0.01 1.89 0 100.00
185 INT32677 Positive_regulation of Npepo 8 0.49 3.1 1.92 100.00
186 INT74866 Positive_regulation of Gene_expression of Apo 4 0.49 4.68 0.93 100.00
187 INT154986 Binding of CRX 3 0.24 3.87 0.53 100.00
188 INT247452 Gene_expression of APOA5 4 0.54 5.71 0.22 100.00
189 INT35263 Gene_expression of Apol7b 5 0.55 4.28 0.64 100.00
190 INT241542 Regulation of Gene_expression of Apob 1 0.00 1.8 0 100.00
191 INT239272 Positive_regulation of Gene_expression of Cand1 3 0.49 4.22 0.08 100.00
192 INT97714 Negative_regulation of Localization of Apoe 1 0.58 1.83 0.97 100.00
193 INT182351 Positive_regulation of Gene_expression of Apoe 38 0.50 19.78 6.72 100.00
194 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 100.00
195 INT194466 Positive_regulation of Apo 6 0.12 4.27 0.13 100.00
196 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 100.00
197 INT14572 Binding of INS 205 0.48 175.43 13.38 100.00
198 INT97708 Regulation of Localization of Apoe 1 0.61 2.06 0.62 100.00
199 INT108917 Positive_regulation of CRX 23 0.50 21.32 10.5 100.00
200 INT267963 Positive_regulation of Apoc1 1 0.01 1.7 0 100.00
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