D:Eating Disorder

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pChart

Disease Term
Synonyms Anorexia Nervosa, APPETITE DISORDER, Appetite Disorders, BINGE EATING, Binge Eating Disorder, Bulimia, Bulimia Nervosa, Bulimic, Bulimic Nervosa, Eating Disorders, Feeding Dysfunction
Documents 758
Hot Single Events 200
Hot Interactions 20

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Eating Disorder. They are ordered first by their relevance to Eating Disorder and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT276438 Binding of OPN1SW and MYP1 1 0.12 1.21 0.09 100.00
2 INT136605 Binding of OPRD1 and RAN 1 0.37 0.54 0.15 100.00
3 INT136606 Binding of RAN and DLL1 1 0.33 0.45 0.15 100.00
4 INT16221 Ghrh Positive_regulation of Gh 8 0.21 1.89 4.08 99.96
5 INT16222 Ghrh Positive_regulation of Ghrh Positive_regulation of Gh 2 0.02 0.51 0.99 99.96
6 INT40127 Lhb Regulation of Localization of PRL 1 0.20 0.41 0.75 99.88
7 INT40126 PRL Regulation of Localization of Lhb 1 0.20 0.41 0.75 99.88
8 INT20186 TRH Regulation of Gene_expression of Gh 1 0.22 0.54 0.22 95.96
9 INT26468 Ghrh Positive_regulation of Localization of Gh 21 0.37 3.26 9.21 93.60
10 INT1390 Trh Positive_regulation of Prl 14 0.67 4.42 4.39 92.88
11 INT60536 Gnrh1 Positive_regulation of Localization of Prl 2 0.22 1.12 0.6 90.44
12 INT17528 Prl Regulation of Gh 2 0.28 1.28 0.73 88.40
13 INT25375 Trh Regulation of Gh 1 0.04 1.01 0.28 88.40
14 INT1392 Trh Regulation of Prl 15 0.29 2.47 4.29 86.32
15 INT97395 Lep Positive_regulation of Stat3 1 0.67 0.42 0.4 83.52
16 INT222466 Gnrh1 Regulation of Prl 1 0.14 1.16 0.07 82.60
17 INT242413 Regulation of Mch Positive_regulation of Casp3 1 0.05 0.16 0.04 80.96
18 INT242411 Mch Positive_regulation of Casp3 1 0.09 0.15 0.04 80.96
19 INT168110 Binding of Cnr1 and Dbh 1 0.04 0.64 0.47 80.92
20 INT168111 Dbh Positive_regulation of Cnr1 1 0.05 0.64 0.47 80.92
21 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22 77.92
22 INT131194 Creb1 Positive_regulation of Gene_expression of Pdyn 1 0.26 0.08 0.79 77.92
23 INT223318 Binding of ESR1 and ESR2 1 0.40 1.22 0 77.84
24 INT16531 Ghrh Positive_regulation of Localization of Gh1 31 0.64 2.12 14.2 73.92
25 INT51720 Negative_regulation of Ins1 Negative_regulation of Igf1 1 0.12 0.85 0.11 73.76
26 INT224404 Binding of GYPC and PYY 1 0.04 1.48 1.42 72.24
27 INT224403 Binding of CCK and GYPC 1 0.04 0.83 0.77 72.24
28 INT1151 Binding of CCK and GAST 7 0.49 0.73 3.08 65.12
29 INT91305 Binding of Npff and Npffr2 2 0.31 0.64 1.32 64.88
30 INT214149 Binding of Lepr and Pomc 1 0.33 0.21 0.03 59.56
31 INT214167 Binding of DST and Pomc 1 0.03 0.22 0.03 59.56
32 INT214171 Binding of DST and Cartpt 1 0.01 0.21 0.03 59.36
33 INT214148 Binding of Lepr and Cartpt 1 0.09 0.21 0.03 59.36
34 INT187361 Binding of Gabrg1 and Kcnn3 1 0.36 0.13 0.3 56.88
35 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17 54.08
36 INT3616 Trh Positive_regulation of Localization of Gh1 4 0.73 0.49 0.36 52.04
37 INT5132 GNRH1 Regulation of Lhb 2 0.08 0 0.52 50.00
38 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 48.56
39 INT222506 Gnrh1 Regulation of Localization of Prl 1 0.20 0.16 0.08 48.04
40 INT270746 INS Regulation of LEP 1 0.07 0.72 0.11 46.44
41 INT108904 Binding of NPY and Npffr2 1 0.36 0.08 0.26 41.36
42 INT53857 Negative_regulation of Crh Positive_regulation of GNRH1 1 0.13 0.5 0.07 41.04
43 INT222490 Npy Positive_regulation of Localization of Gh1 1 0.02 0.06 0.41 28.56
44 INT83169 Binding of Cck and Lep 7 0.42 1.58 2.78 27.76
45 INT214150 Binding of Mc3r and Msx1 1 0.03 0.5 0.12 25.52
46 INT266102 Binding of PITX2 and RS1 1 0.00 0.64 0.8 22.52
47 INT179950 Binding of PIK3CA and Irs1 1 0.32 0.31 0.03 22.52
48 INT179949 Binding of Ins1 and Irs1 1 0.31 0.32 0.03 22.52
49 INT179951 Binding of PIK3CA and Ins1 1 0.39 0.32 0.03 22.12
50 INT280831 Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0 0 14.96
51 INT280823 Positive_regulation of Prkaca Positive_regulation of Gene_expression of Crh 1 0.08 0.11 0 9.68
52 INT2161 Gnrh1 Positive_regulation of Localization of LH 33 0.73 0.87 14.34 5.00
53 INT2714 Pomc Positive_regulation of Localization of Prl 17 0.79 0.5 8.18 5.00
54 INT106559 Binding of Bdnf and Ntrk2 23 0.43 11.09 7.33 5.00
55 INT20133 Trh Positive_regulation of Localization of Prl 23 0.78 2.04 5.44 5.00
56 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71 5.00
57 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 5.00
58 INT31513 Crh Regulation of POMC 3 0.29 5.06 2.78 5.00
59 INT214144 Cck Positive_regulation of Pomc 1 0.15 0.94 2.39 5.00
60 INT214159 Cck Positive_regulation of Nts 1 0.03 0.93 2.34 5.00
61 INT60626 Crh Positive_regulation of Localization of Pomc 7 0.54 2.3 1.99 5.00
62 INT9786 Gnrh1 Regulation of LH 7 0.40 0.58 1.82 5.00
63 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66 5.00
64 INT32482 Ghrh Positive_regulation of Prl 3 0.18 0.26 1.62 5.00
65 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25 5.00
66 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2 5.00
67 INT222516 Binding of Calcrl and Ramp1 5 0.17 0.11 1.12 5.00
68 INT36186 Npy Positive_regulation of Localization of Gnrh1 4 0.75 0.09 0.96 5.00
69 INT81127 Binding of Gabrd and Abat 3 0.25 0 0.96 5.00
70 INT206857 Binding of Calca and Calcrl 4 0.37 1.9 0.95 5.00
71 INT232426 HRH2 Regulation of Localization of PRL 1 0.15 0.38 0.94 5.00
72 INT78062 Il1a Positive_regulation of Localization of Il6 3 0.24 0.48 0.9 5.00
73 INT295552 Binding of Ghrl and Ghsr 7 0.40 1.64 0.88 5.00
74 INT122191 Binding of Crh and Ucn 4 0.36 0.79 0.82 5.00
75 INT243024 Binding of Dcpp1 and Slc6a4 1 0.08 0.42 0.76 5.00
76 INT243025 Dcpp1 Regulation of Slc6a4 1 0.10 0.43 0.76 5.00
77 INT222528 Abat Positive_regulation of Gene_expression of Gh1 1 0.01 0 0.75 5.00
78 INT152429 Ghrh Positive_regulation of Localization of Gh 4 0.37 0.56 0.75 5.00
79 INT266100 Binding of COMT and SH2B2 1 0.25 1.22 0.74 5.00
80 INT327707 Binding of Comt and Drd1a 1 0.18 0.27 0.74 5.00
81 INT266108 Binding of COMT and HPS1 1 0.23 1.21 0.74 5.00
82 INT327702 Binding of Comt and Drd2 1 0.28 0.27 0.74 5.00
83 INT327712 Binding of Comt and Rbm39 1 0.00 0.27 0.74 5.00
84 INT214163 Binding of Lep and Nts 1 0.04 0.21 0.74 5.00
85 INT123229 OXTR Regulation of Localization of PRL 2 0.30 0 0.73 5.00
86 INT216668 Positive_regulation of NLRP1 Regulation of Vta1 1 0.00 0 0.73 5.00
87 INT222432 Binding of Tlr4 and Cd14 1 0.02 0.74 0.71 5.00
88 INT222493 Edn1 Positive_regulation of Localization of Prl 1 0.10 0 0.71 5.00
89 INT32715 Prl Regulation of Localization of LH 2 0.34 0.09 0.68 5.00
90 INT60283 Positive_regulation of Gnrh1 Regulation of LH 2 0.31 0 0.68 5.00
91 INT122190 Binding of Crhr1 and Ucn 4 0.49 0.65 0.67 5.00
92 INT222552 Abat Regulation of Gene_expression of Gh1 1 0.00 0 0.67 5.00
93 INT33561 Crh Positive_regulation of POMC 3 0.45 1.19 0.64 5.00
94 INT222492 Ngf Positive_regulation of Gene_expression of Prl 1 0.24 0 0.62 5.00
95 INT3617 Trh Regulation of Localization of Gh1 3 0.65 0.55 0.62 5.00
96 INT89902 SST Positive_regulation of Localization of PRL 2 0.40 0 0.61 5.00
97 INT27067 Crh Positive_regulation of Localization of Avp 3 0.18 0.46 0.61 5.00
98 INT32747 Avp Positive_regulation of Localization of Pomc 4 0.16 1.92 0.61 5.00
99 INT222521 Vip Positive_regulation of Localization of Ngf 1 0.14 0.08 0.6 5.00
100 INT222554 Il1a Positive_regulation of Localization of Ngf 1 0.02 0.07 0.6 5.00
101 INT93063 Binding of gr and Jun 3 0.14 0.79 0.57 5.00
102 INT149473 Avp Positive_regulation of Localization of Pomc 4 0.48 2.64 0.56 5.00
103 INT214160 Binding of Lep and Mc4r 1 0.29 1.31 0.53 5.00
104 INT214164 Binding of Mc4r and Pomc 1 0.39 1.31 0.53 5.00
105 INT214143 Binding of Lep and Pomc 1 0.27 1.2 0.53 5.00
106 INT232424 VIP Positive_regulation of Localization of PRL 1 0.36 0 0.53 5.00
107 INT222524 Abat Negative_regulation of Localization of Trh 1 0.02 0.16 0.51 5.00
108 INT172207 Binding of Drd4 and ADHD1 2 0.03 1.56 0.48 5.00
109 INT280826 Il6 Positive_regulation of Localization of Avp 1 0.01 0.64 0.47 5.00
110 INT214162 Gabrg1 Negative_regulation of Pomc 1 0.05 0.65 0.46 5.00
111 INT232427 ABAT Regulation of PRL 1 0.08 0.26 0.45 5.00
112 INT325391 Binding of Ghrl and Ghsr 2 0.17 0.14 0.43 5.00
113 INT323484 Ghsr Positive_regulation of Localization of Ins1 1 0.27 0.87 0.43 5.00
114 INT287697 QRFP Regulation of Gene_expression of TNF 1 0.40 1.23 0.42 5.00
115 INT214151 Gabrg1 Negative_regulation of Gene_expression of Agrp 1 0.04 0.52 0.4 5.00
116 INT214147 Gabrg1 Negative_regulation of Gene_expression of Npy 1 0.03 0.52 0.4 5.00
117 INT323491 Olfr781 Positive_regulation of Localization of Ins1 1 0.01 0.87 0.4 5.00
118 INT222418 Tlr4 Positive_regulation of Gene_expression of Il1a 1 0.00 0.31 0.39 5.00
119 INT297738 Cbr1 Positive_regulation of Ifih1 1 0.01 1.83 0.39 5.00
120 INT122188 Binding of Crh and Ucn2 2 0.22 0.29 0.38 5.00
121 INT214140 Agrp Positive_regulation of Mc3r 1 0.34 0.23 0.37 5.00
122 INT232422 VIP Regulation of Gene_expression of PRL 1 0.40 0 0.37 5.00
123 INT214158 Binding of Agrp and Mc3r 1 0.35 0.18 0.37 5.00
124 INT232421 Binding of PRL and Positive_regulation of Regulation of ABAT 1 0.09 0 0.37 5.00
125 INT214142 Agrp Positive_regulation of Mc4r 1 0.39 0.23 0.37 5.00
126 INT214145 Binding of Agrp and Mc4r 1 0.40 0.18 0.37 5.00
127 INT327708 Binding of Drd1a and Drd2 1 0.12 0.12 0.37 5.00
128 INT122189 Binding of Crhr1 and Ucn2 2 0.08 0.27 0.36 5.00
129 INT232419 ABAT Positive_regulation of Localization of PRL 1 0.09 0 0.33 5.00
130 INT280808 Prkcg Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
131 INT280838 Binding of Crh and gr 1 0.06 0 0.33 5.00
132 INT232425 Binding of ABAT and Positive_regulation of PRL 1 0.09 0.15 0.33 5.00
133 INT214157 Positive_regulation of Mc3r Regulation of Npy 1 0.14 0.49 0.33 5.00
134 INT280814 Positive_regulation of Mapk1 Positive_regulation of Transcription of Fos 1 0.02 0.06 0.33 5.00
135 INT232420 PRL Positive_regulation of Regulation of ABAT 1 0.09 0 0.33 5.00
136 INT323502 Ghrl Positive_regulation of Localization of Ins1 1 0.15 1.58 0.33 5.00
137 INT222441 Tlr4 Positive_regulation of Gene_expression of Tac1 1 0.00 0.39 0.32 5.00
138 INT255740 Pik3r1 Positive_regulation of Akt1 5 0.24 2.42 0.31 5.00
139 INT222464 Col4a2 Regulation of Localization of Prl 1 0.03 0.32 0.3 5.00
140 INT327701 Comt Regulation of Npcd 1 0.01 0 0.29 5.00
141 INT222529 Binding of Trh and Vip 1 0.07 0.09 0.29 5.00
142 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29 5.00
143 INT327706 Comt Regulation of Gopc 1 0.10 0 0.29 5.00
144 INT126696 Binding of Crhr1 and Crh 3 0.50 0.44 0.29 5.00
145 INT280827 Positive_regulation of Fos Positive_regulation of Avp 1 0.02 0.08 0.28 5.00
146 INT280825 Mapk1 Positive_regulation of Avp 1 0.01 0.08 0.28 5.00
147 INT177476 Gnrhr Positive_regulation of Localization of Igf1 1 0.05 1.01 0.28 5.00
148 INT280807 Mapk1 Positive_regulation of Positive_regulation of Prkcg 1 0.01 0.08 0.28 5.00
149 INT177478 Gnrhr Positive_regulation of Localization of IGF1 1 0.04 1.01 0.28 5.00
150 INT280832 Binding of Crh and Ucn3 1 0.16 0.07 0.27 5.00
151 INT280850 Binding of Crh and Ucn Positive_regulation of Negative_regulation of Crh 1 0.26 0.06 0.27 5.00
152 INT222428 Negative_regulation of Tlr4 Positive_regulation of Il6 1 0.01 0.26 0.27 5.00
153 INT280822 Jun Regulation of Regulation of Crh 1 0.20 0.08 0.27 5.00
154 INT222412 Cd14 Negative_regulation of Binding of Tlr4 1 0.02 0.26 0.27 5.00
155 INT224406 INS Regulation of Localization of PYY 1 0.11 0.27 0.27 5.00
156 INT224405 INS Regulation of Localization of CCK 1 0.12 0.27 0.27 5.00
157 INT222440 Tlr4 Positive_regulation of Localization of Pomc 1 0.01 0.35 0.27 5.00
158 INT280805 Positive_regulation of Prkcg Positive_regulation of Avp 1 0.01 0.16 0.26 5.00
159 INT222427 Il6 Positive_regulation of Localization of Pomc 1 0.02 0.27 0.26 5.00
160 INT222422 Tlr4 Positive_regulation of Il6 1 0.01 0.25 0.26 5.00
161 INT222467 Gh1 Positive_regulation of Prl 1 0.04 0.52 0.26 5.00
162 INT280811 Binding of Crhr1 and Ucn3 1 0.08 0.05 0.25 5.00
163 INT222557 Gal Positive_regulation of Gene_expression of Vip 1 0.06 0.07 0.25 5.00
164 INT222421 Tlr4 Negative_regulation of Localization of Prl 1 0.02 0.45 0.25 5.00
165 INT222563 Vip Positive_regulation of Gene_expression of Il6 1 0.05 0.38 0.25 5.00
166 INT222560 Calca Positive_regulation of Gene_expression of Il6 1 0.06 0.39 0.25 5.00
167 INT222540 Mzb1 Positive_regulation of Gene_expression of Il6 1 0.03 0.38 0.25 5.00
168 INT335028 Fgf15 Positive_regulation of Fgfr4 1 0.40 0.31 0.25 5.00
169 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24 5.00
170 INT222561 Gnrh1 Positive_regulation of Prl 1 0.15 0.38 0.22 5.00
171 INT177477 Crh Positive_regulation of Crh Regulation of POMC 1 0.02 0.86 0.22 5.00
172 INT121050 Crh Regulation of Localization of Pomc 4 0.43 0.6 0.22 5.00
173 INT222527 Gal Regulation of Vip 1 0.03 0.05 0.22 5.00
174 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 5.00
175 INT335025 Gm7647 Positive_regulation of Gene_expression of Fgf21 1 0.01 0.29 0.21 5.00
176 INT58243 Ghrh Regulation of Prl 1 0.04 0.18 0.21 5.00
177 INT266103 Binding of COMT and SNRNP70 1 0.04 0.78 0.21 5.00
178 INT222566 Agt Positive_regulation of Localization of Prl 1 0.08 0.23 0.21 5.00
179 INT177479 Negative_regulation of Crh Regulation of POMC 1 0.05 0.84 0.21 5.00
180 INT222482 Lep Positive_regulation of Localization of Gh1 1 0.02 1.02 0.2 5.00
181 INT179689 Binding of CYP4F3 and DAK 1 0.00 1.23 0.2 5.00
182 INT300562 Binding of Slc6a3 and Datd 1 0.02 1.12 0.2 5.00
183 INT280820 S100a8 Positive_regulation of Gene_expression of Crh 1 0.01 0.65 0.19 5.00
184 INT312708 DPP8 Positive_regulation of DPP4 1 0.24 0.54 0.19 5.00
185 INT222568 Vip Negative_regulation of Transcription of Nos2 1 0.06 0.3 0.19 5.00
186 INT268797 Ghrh Positive_regulation of Transcription of Gh 1 0.20 0.33 0.19 5.00
187 INT312706 DPP9 Positive_regulation of DPP4 1 0.26 0.54 0.19 5.00
188 INT222543 Il1a Regulation of Chat 1 0.01 0.64 0.19 5.00
189 INT280839 Il6 Positive_regulation of Gene_expression of Crh 1 0.09 0.1 0.19 5.00
190 INT222525 Il1a Regulation of Localization of Gh1 1 0.00 0.64 0.19 5.00
191 INT222499 Il10 Regulation of Positive_regulation of Hpse 1 0.00 0.8 0.19 5.00
192 INT222473 Mzb1 Negative_regulation of Transcription of Nos2 1 0.04 0.29 0.19 5.00
193 INT300563 Binding of Drd5 and ADHD1 1 0.01 1.13 0.19 5.00
194 INT217661 LEP Positive_regulation of INS 2 0.25 1.85 0.19 5.00
195 INT217665 ADIPOQ Positive_regulation of INS 2 0.06 1.8 0.19 5.00
196 INT222494 Negative_regulation of Il1a Negative_regulation of Positive_regulation of Il6 1 0.00 0.79 0.19 5.00
197 INT222531 Il6 Positive_regulation of Hpse 1 0.00 0.61 0.18 5.00
198 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18 5.00
199 INT214170 Binding of DST and Lep 1 0.02 0.17 0.18 5.00
200 INT222661 IFNA1 Positive_regulation of Gene_expression of Nos1 1 0.01 0.25 0.18 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Eating Disorder. They are ordered first by their pain relevance and then by number of times they were reported in Eating Disorder. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT117731 Binding of MYP1 7 0.30 10.61 0.67 100.00
2 INT51047 Regulation of Drd3 4 0.53 2 2.2 100.00
3 INT5501 Regulation of Oprd1 283 0.62 55.1 249.9 100.00
4 INT276439 Positive_regulation of Positive_regulation of MYP1 1 0.31 1.36 0 100.00
5 INT48911 Binding of NOS1 24 0.40 11.21 5.89 100.00
6 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 100.00
7 INT12392 Regulation of Slc3a1 45 0.36 7.57 25.66 100.00
8 INT310056 Negative_regulation of MYP1 2 0.27 2.49 0.4 100.00
9 INT181587 Negative_regulation of OPN1SW 12 0.51 4.36 0.89 100.00
10 INT276440 Gene_expression of MYP1 2 0.42 1.1 0.12 100.00
11 INT136611 Positive_regulation of Binding of HTR1D 1 0.48 0.45 0.15 100.00
12 INT136609 Positive_regulation of Binding of DLL1 1 0.49 0.45 0.15 100.00
13 INT29416 Positive_regulation of Binding of OPRD1 2 0.47 0.52 1.31 100.00
14 INT5311 Regulation of Negative_regulation of Oprd1 11 0.43 0.99 7.23 100.00
15 INT6438 Positive_regulation of RAN 6 0.42 2.09 1.59 100.00
16 INT141924 Positive_regulation of MYP1 3 0.45 2.03 0.64 100.00
17 INT141285 Positive_regulation of Localization of Ghrl 11 0.63 9.38 3.86 100.00
18 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 99.98
19 INT6278 Negative_regulation of Gene_expression of Pomc 35 0.59 11.07 14.8 99.98
20 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 99.96
21 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 99.96
22 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.94
23 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 99.92
24 INT894 Binding of Avp 84 0.48 29.16 29.63 99.92
25 INT108796 Binding of ESR2 5 0.46 6.84 2.36 99.92
26 INT5533 Binding of Oxt 43 0.48 8.69 18.35 99.92
27 INT4937 Negative_regulation of Oprd1 224 0.59 44.51 171.11 99.90
28 INT164017 Negative_regulation of Localization of Ghrl 2 0.53 3.12 1.88 99.90
29 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 99.88
30 INT12318 Negative_regulation of Positive_regulation of Cort 7 0.43 3.89 2.65 99.86
31 INT12319 Positive_regulation of Cort 52 0.61 22.55 29.35 99.86
32 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.84
33 INT738 Regulation of POMC 459 0.62 111.19 243.74 99.84
34 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 99.84
35 INT161 Regulation of Localization of Prl 615 0.62 65.37 298.66 99.84
36 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 99.84
37 INT6437 Binding of YY1 154 0.47 26.3 90.46 99.84
38 INT462 Regulation of Pomc 157 0.62 41.67 67.27 99.84
39 INT187359 Negative_regulation of Mvp 1 0.06 1.12 0.12 99.84
40 INT297642 Regulation of crf 5 0.19 3.52 0.05 99.84
41 INT7786 Positive_regulation of Ptgdr 26 0.47 5.62 14.99 99.82
42 INT5016 Negative_regulation of Crh 129 0.59 36.74 59.28 99.82
43 INT56883 Positive_regulation of Dll1 8 0.49 3.49 12.25 99.82
44 INT68635 Negative_regulation of Ceacam3 7 0.55 3.16 7.85 99.82
45 INT6934 Binding of OPRD1 51 0.48 7.72 25.73 99.76
46 INT6270 Binding of HTR1D 55 0.47 9.54 22.86 99.76
47 INT40036 Binding of DLL1 10 0.36 2.88 3.95 99.76
48 INT11510 Negative_regulation of Positive_regulation of Gh 28 0.52 12.71 9.16 99.76
49 INT14513 Localization of Ghrl 52 0.78 29.26 11.63 99.74
50 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 99.66
51 INT82077 Positive_regulation of Gene_expression of Lep 32 0.70 17.9 3.5 99.66
52 INT12316 Negative_regulation of Cort 10 0.38 5.89 6.08 99.66
53 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 99.64
54 INT9210 Regulation of IL6 166 0.62 125.61 49.95 99.64
55 INT5948 Regulation of Il1b 44 0.60 22.8 25.4 99.64
56 INT874 Positive_regulation of Gh1 244 0.70 27.17 97.98 99.64
57 INT4298 Positive_regulation of Positive_regulation of Gh1 30 0.50 1.79 13.32 99.64
58 INT4299 Positive_regulation of Gene_expression of Gh1 27 0.50 5.24 7.31 99.64
59 INT443 Localization of POMC 1020 0.81 284.52 443.17 99.60
60 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 99.60
61 INT847 Regulation of Lhb 131 0.61 22.08 46.54 99.56
62 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.56
63 INT31981 Regulation of Regulation of Lhb 4 0.44 1.03 1.57 99.56
64 INT162 Regulation of Prl 794 0.62 165.01 322.24 99.54
65 INT615 Regulation of Alb 66 0.62 33.43 15.33 99.54
66 INT82082 Localization of Lep 63 0.81 26.41 8.56 99.48
67 INT5127 Localization of Lhb 488 0.80 50.48 162.66 99.44
68 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.44
69 INT6115 Positive_regulation of Pigm 82 0.64 16.96 25.73 99.44
70 INT16883 Positive_regulation of Gene_expression of Pigm 11 0.39 3.93 6.89 99.44
71 INT5710 Negative_regulation of Localization of Lhb 146 0.57 20.51 58.33 99.40
72 INT6299 Regulation of Localization of Lhb 104 0.61 8.98 48.79 99.40
73 INT73641 Regulation of Lep 45 0.62 26.2 12.59 99.40
74 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 99.36
75 INT214106 Gene_expression of Cartpt 21 0.73 3.68 7.84 99.36
76 INT16527 Negative_regulation of Positive_regulation of Ghrh 6 0.43 1.01 2.23 99.36
77 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.34
78 INT96047 Positive_regulation of Localization of NOS1 6 0.38 4.24 1.47 99.32
79 INT5339 Positive_regulation of Positive_regulation of Npy 13 0.68 4.5 8.15 99.32
80 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 99.30
81 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.28
82 INT10272 Gene_expression of Il1b 194 0.78 121.02 103.03 99.28
83 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8 99.28
84 INT1793 Localization of CGA 379 0.81 67.38 114.69 99.28
85 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 99.28
86 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.28
87 INT55944 Positive_regulation of Cpox 214 0.57 105.14 81.4 99.28
88 INT1794 Regulation of Localization of CGA 136 0.57 13.39 59.07 99.28
89 INT335006 Negative_regulation of Gene_expression of Fgf21 1 0.41 1.33 0.03 99.28
90 INT334980 Negative_regulation of Fgf21 1 0.41 2.31 0.03 99.28
91 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 99.24
92 INT1378 Negative_regulation of Regulation of Prl 27 0.43 9.16 9.9 99.24
93 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 99.24
94 INT871 Negative_regulation of Gene_expression of Prl 53 0.58 18.89 17.79 99.24
95 INT5130 Regulation of GNRH1 139 0.62 31.95 42.08 99.20
96 INT2159 Regulation of Localization of Gnrh1 200 0.62 13.28 99.07 99.20
97 INT48912 Localization of NOS1 52 0.77 24.14 10.92 99.18
98 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 99.18
99 INT12751 Gene_expression of Pigm 91 0.58 22.42 29.2 99.16
100 INT12117 Regulation of Negative_regulation of Oprl1 6 0.44 1.49 2.82 99.08
101 INT873 Gene_expression of Gh1 130 0.76 26.15 46.75 99.04
102 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 99.02
103 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 99.00
104 INT8524 Regulation of Transcription of Pdyn 20 0.60 5.47 9.03 98.96
105 INT5594 Regulation of Pdyn 137 0.62 27.04 86.63 98.96
106 INT15459 Gene_expression of TRH 17 0.78 4.89 8.17 98.92
107 INT187355 Gene_expression of Kcnn1 2 0.28 1.47 0.86 98.92
108 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75 98.90
109 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 98.88
110 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.88
111 INT6826 Transcription of Pdyn 130 0.71 22.19 54.88 98.84
112 INT5372 Localization of LHB 55 0.68 9.47 19 98.84
113 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 98.82
114 INT1395 Negative_regulation of Penk 537 0.59 87.33 389.81 98.82
115 INT6823 Negative_regulation of Pdyn 68 0.58 13.95 46.12 98.82
116 INT5598 Negative_regulation of Pdyn 95 0.59 14.4 55.43 98.82
117 INT22337 Negative_regulation of Transcription of Pomc 12 0.59 2.17 4.32 98.82
118 INT2330 Regulation of CB 78 0.10 20.46 32.6 98.78
119 INT425 Localization of PRL 455 0.81 189.64 144.8 98.76
120 INT2059 Positive_regulation of Negative_regulation of Prl 24 0.70 5.7 9.37 98.72
121 INT7833 Positive_regulation of Cck 33 0.70 8.54 34.21 98.72
122 INT314554 Gene_expression of Fgf21 3 0.74 7.97 2.48 98.72
123 INT108896 Transcription of Npffr2 2 0.72 1.25 1.56 98.72
124 INT218578 Positive_regulation of GYPC 10 0.37 5.7 1.92 98.70
125 INT1596 Negative_regulation of Oprl1 61 0.57 13.5 38.41 98.68
126 INT5711 Positive_regulation of Localization of Lhb 90 0.70 10.92 36.76 98.64
127 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 98.60
128 INT187360 Gene_expression of Kcnn2 17 0.55 2.51 3.91 98.60
129 INT97392 Gene_expression of Stat3 27 0.65 14.21 4.06 98.60
130 INT6277 Positive_regulation of Gene_expression of Pomc 76 0.70 21.45 31.09 98.60
131 INT97394 Regulation of Stat3 6 0.41 2.52 1.34 98.60
132 INT1530 Regulation of Gh 382 0.61 115.96 112.47 98.56
133 INT20179 Positive_regulation of Regulation of Gh 12 0.54 3.99 3.42 98.56
134 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45 98.56
135 INT5604 Positive_regulation of Drd2 47 0.67 10.75 27.41 98.52
136 INT6108 Gene_expression of Npy 292 0.78 110.65 148.21 98.52
137 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 98.48
138 INT4803 Transcription of Penk 435 0.72 59.09 182.4 98.48
139 INT26972 Negative_regulation of Tenc1 57 0.57 56.71 16.87 98.48
140 INT12159 Transcription of Cck 46 0.72 9.36 37.58 98.48
141 INT7326 Transcription of Th 83 0.72 13.5 35.33 98.48
142 INT20579 Transcription of Akr1d1 9 0.04 2.91 8.37 98.48
143 INT54355 Transcription of Slc6a3 6 0.61 0.28 3.02 98.48
144 INT15505 Regulation of nt 6 0.24 1.5 1.88 98.44
145 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93 98.40
146 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 98.38
147 INT54363 Gene_expression of Htr1d 13 0.75 3.8 7.59 98.36
148 INT2276 Regulation of Ins1 234 0.61 103.78 54.05 98.32
149 INT150825 Binding of Comt 13 0.42 6.65 6.42 98.32
150 INT107291 Positive_regulation of Ghrl 58 0.67 44.6 9.68 98.30
151 INT6042 Binding of Oprm1 248 0.48 31.77 154.34 98.28
152 INT125147 Binding of Mc4r 10 0.41 3.55 1.08 98.20
153 INT1377 Positive_regulation of Trh 172 0.70 40.55 69.83 98.16
154 INT6441 Positive_regulation of CRH 98 0.69 57.22 24.12 98.16
155 INT1562 Localization of Crh 499 0.81 126.74 236.68 98.16
156 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 98.12
157 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49 98.08
158 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 98.08
159 INT19008 Positive_regulation of Positive_regulation of Ghrh 15 0.49 2.4 4.55 98.08
160 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 98.00
161 INT5283 Positive_regulation of Npy 191 0.70 66.77 109.2 98.00
162 INT5340 Negative_regulation of Positive_regulation of Npy 12 0.55 3.83 8.23 98.00
163 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 97.88
164 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 97.88
165 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 97.80
166 INT115401 Negative_regulation of P2ry1 6 0.42 1.27 2.25 97.76
167 INT272772 Gene_expression of Fto 2 0.76 3.76 0.52 97.76
168 INT2651 Positive_regulation of Pomc 403 0.70 95.72 206.24 97.64
169 INT5506 Positive_regulation of Gene_expression of Pomc 132 0.70 26.78 54.3 97.64
170 INT7565 Transcription of Pomc 69 0.72 14.46 27.41 97.60
171 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 97.52
172 INT2884 Positive_regulation of CCK 66 0.69 25.25 30.6 97.36
173 INT203020 Positive_regulation of PYY 37 0.68 18.81 9.63 97.36
174 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81 97.28
175 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32 97.24
176 INT11300 Positive_regulation of Gene_expression of Avp 24 0.50 10.18 2.69 97.20
177 INT52402 Negative_regulation of Htr2c 7 0.42 1.46 4.21 97.16
178 INT52403 Negative_regulation of HTR2B 5 0.42 1.79 3.15 97.16
179 INT132411 Positive_regulation of Ghrl 25 0.69 12.05 2.59 97.00
180 INT3359 Regulation of YY1 32 0.60 8.19 19.2 96.88
181 INT110389 Regulation of Htr1d 2 0.44 1.13 2.26 96.88
182 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 96.76
183 INT11303 Gene_expression of Avp 116 0.78 39.23 23.88 96.48
184 INT10929 Positive_regulation of FLII 46 0.67 13.17 24.63 96.44
185 INT73642 Positive_regulation of Ctse 12 0.44 5.57 6.79 96.44
186 INT4207 Regulation of Avp 267 0.62 63.72 115.33 96.32
187 INT451 Regulation of Oxt 142 0.62 22.07 69.42 96.32
188 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 96.24
189 INT214581 Negative_regulation of GYPC 32 0.32 21.93 3.62 96.24
190 INT100195 Negative_regulation of SPANXB1 5 0.48 2.7 0.82 96.08
191 INT16219 Negative_regulation of Regulation of Ghrh 1 0.11 0.5 0.27 96.04
192 INT16220 Negative_regulation of Regulation of Gh 13 0.42 3.59 4.33 96.04
193 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11 96.02
194 INT14559 Gene_expression of Igf1 254 0.78 112 34.17 95.80
195 INT132036 Negative_regulation of DPP4 126 0.59 63.24 9.51 95.68
196 INT6323 Positive_regulation of Gabrg1 213 0.70 45.08 124.34 95.60
197 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 95.56
198 INT33996 Positive_regulation of Negative_regulation of Oprl1 4 0.53 1.34 2.68 95.56
199 INT3276 Binding of LH 16 0.37 4.76 5.94 95.52
200 INT26282 Negative_regulation of ELN 9 0.51 6.37 3.76 95.48
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