D:Experimental Arthritis

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pChart

Disease Term
Synonyms Adjuvant Arthritis, Arthritides Collagen, ARTHRITIS ADJUVANT, Arthritis Adjuvant Induced, Arthritis Collagen, Arthritis Collagen Induced, Collagen Arthritides, Collagen Arthritis, Collagen Induced Arthritides, Collagen Induced Arthritis
Documents 416
Hot Single Events 200
Hot Interactions 67

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Experimental Arthritis. They are ordered first by their relevance to Experimental Arthritis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT224580 Gene_expression of IL18 Positive_regulation of SERPINH1 1 0.00 1.34 0.7 100.00
2 INT1066 Gm5720 Positive_regulation of MBD2 1 0.00 0.73 0.42 99.80
3 INT21331 Binding of Adarb1 and Gm5195 1 0.00 0.26 1.08 99.40
4 INT21329 Binding of Man2a2 and Gm5195 1 0.00 0.26 1.06 99.40
5 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1 99.40
6 INT21330 Binding of Htr1f and Gm5195 1 0.00 0.26 0.99 99.40
7 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 98.64
8 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13 98.60
9 INT53103 Igh-Dex Negative_regulation of Cia1 1 0.10 1.23 0.98 98.52
10 INT252344 Binding of Cd40 and Mthfd1 2 0.16 0.34 0.08 98.24
11 INT237379 Binding of Ebi3 and Il27 2 0.05 1.71 0.82 98.16
12 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 97.84
13 INT70803 Ngf Regulation of Tac4 1 0.06 0.39 0.93 97.36
14 INT70802 Ngf Regulation of Ppt1 1 0.21 0.39 0.93 97.36
15 INT311988 Il4 Positive_regulation of Mthfd1 1 0.08 0.28 0.08 96.80
16 INT311986 Csf2 Positive_regulation of Mthfd1 1 0.03 0.28 0.08 96.80
17 INT339645 Binding of Cdk5r1 and Ebi3 1 0.01 0.78 0.31 96.76
18 INT196586 Negative_regulation of Mapk14 Negative_regulation of TNF 2 0.04 2.02 2.08 96.32
19 INT171905 TNF Positive_regulation of Gene_expression of Il1 2 0.23 1.08 0.54 95.08
20 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15 94.96
21 INT323840 Binding of Esr1 and Il1 1 0.04 0.9 0.42 94.80
22 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 94.80
23 INT336017 Vip Regulation of Tlr4 1 0.22 1.23 0.93 94.72
24 INT311989 Binding of Chuk and Mthfd1 1 0.05 0.56 0.24 93.96
25 INT19513 Prl Positive_regulation of IL2 1 0.41 0.8 0.27 91.60
26 INT264327 IL-17 Positive_regulation of Gene_expression of Tnfsf11 1 0.07 3.19 1.33 91.04
27 INT172136 IL18 Positive_regulation of Gene_expression of IFN1@ 1 0.09 0.63 0.42 90.96
28 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15 90.40
29 INT172145 IL10 Negative_regulation of Gene_expression of CSF2 1 0.04 0.69 0.59 89.52
30 INT299783 Binding of Cd28 and Cd80 7 0.14 6.49 2.49 89.04
31 INT184094 Gene_expression of Socs3 Negative_regulation of Positive_regulation of Il6 1 0.12 1.49 0.48 88.44
32 INT173937 Hrt1 Regulation of Il1 1 0.00 0.28 0.13 88.40
33 INT278691 MTX1 Negative_regulation of DHFR 1 0.02 0.57 0.49 88.36
34 INT134993 P2rx6 Regulation of Ephb1 1 0.20 1.27 0.87 87.84
35 INT200469 Binding of COL7A1 and COMP 1 0.04 0.91 0.38 87.76
36 INT327309 Il1 Positive_regulation of Mapk14 1 0.01 0.36 0.14 87.68
37 INT200094 Negative_regulation of Jun Negative_regulation of Gene_expression of Ptgs2 1 0.01 2.87 0.78 87.32
38 INT200096 Negative_regulation of Il1a Negative_regulation of Gene_expression of Ptgs2 1 0.00 1.45 0.39 87.32
39 INT187116 TIMP2 Negative_regulation of MMP9 1 0.36 1.37 0.5 87.28
40 INT333763 Il27 Positive_regulation of Gene_expression of Il10 2 0.22 0.8 0.26 87.20
41 INT19512 Prl Positive_regulation of Odc1 1 0.01 0.89 0.31 87.12
42 INT222522 Il1a Positive_regulation of Gene_expression of Il6 2 0.06 1.79 2.79 87.08
43 INT196585 Mapk14 Regulation of TNF 1 0.02 0.36 0.55 86.72
44 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15 86.16
45 INT327329 S100a8 Positive_regulation of Mapk14 1 0.00 0.36 0.14 85.84
46 INT327330 Mapk14 Regulation of Il1 1 0.01 0.33 0.12 85.80
47 INT184262 Binding of AGER and HMGB1 1 0.34 4.49 2.17 85.44
48 INT200097 Negative_regulation of Binding of Il1a and Jun 1 0.00 2.76 0.77 85.04
49 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21 84.80
50 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69 84.72
51 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69 84.72
52 INT200093 Binding of Il1a and Jun 1 0.00 2.64 0.76 84.44
53 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2 84.16
54 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68 84.08
55 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68 84.08
56 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18 83.84
57 INT187102 Negative_regulation of Binding of MMP9 and TIMP2 1 0.36 0.69 0.3 83.36
58 INT187106 Binding of MMP9 and TIMP2 1 0.30 0.69 0.3 83.36
59 INT187113 Binding of IGHG3 and MMP9 1 0.01 0.63 0.3 82.52
60 INT231732 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 81.88
61 INT231733 Binding of Tnfrsf11a and Tnfsf11 1 0.01 1.03 0.48 81.36
62 INT196577 Negative_regulation of Mapk14 Negative_regulation of Il6 1 0.13 0.45 0.78 81.32
63 INT196574 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il6 1 0.13 0.45 0.78 81.32
64 INT196575 Negative_regulation of Mapk14 Negative_regulation of Gene_expression of Il1a 1 0.04 0.44 0.77 81.32
65 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 80.88
66 INT327326 Binding of Mapkapk2 and Ttpa 1 0.02 0.34 0.14 80.80
67 INT327319 Binding of Mapk14 and Ttpa 1 0.01 0.34 0.14 80.80
68 INT278688 MTX1 Negative_regulation of Positive_regulation of SOAT1 1 0.04 0.69 0.54 76.40
69 INT278695 MTX1 Negative_regulation of Phosphorylation of AKT1 1 0.04 0.81 0.62 73.80
70 INT25354 Chi3l1 Negative_regulation of Ptgs1 1 0.00 0.39 0.34 72.92
71 INT264338 Binding of IL-17 and Positive_regulation of Localization of TNF 1 0.04 1.71 0.67 72.80
72 INT171874 Binding of SQLE and MRAP 1 0.00 1.29 0.35 72.00
73 INT264329 Binding of IL-17 and Positive_regulation of Localization of Ccl2 1 0.13 1.65 0.64 70.96
74 INT224688 Pten Regulation of Akt1 1 0.04 1.12 0.19 70.00
75 INT264334 Binding of IL-17 and Positive_regulation of Localization of Csf3 1 0.13 1.64 0.63 68.40
76 INT182051 Il18 Positive_regulation of Il1 1 0.18 0.77 0.38 67.28
77 INT239042 Il17a Negative_regulation of Gene_expression of Il6 1 0.03 0.82 0.42 66.92
78 INT101942 Binding of CD40 and CD40LG 16 0.23 15.24 4.01 66.00
79 INT224680 Tgfb1 Negative_regulation of Pten 1 0.00 1.19 0.18 65.08
80 INT289251 Ptpn11 Regulation of Il6 1 0.09 0.86 0.18 64.80
81 INT264335 Binding of IL-17 and Positive_regulation of Localization of Il6 1 0.13 1.62 0.62 64.80
82 INT100018 TNF Positive_regulation of MAPK1 3 0.24 1.56 0.94 64.60
83 INT278694 TNF Positive_regulation of MAPK14 1 0.03 0.79 0.56 64.60
84 INT278689 TNF Positive_regulation of MAPK8 1 0.04 0.79 0.56 64.60
85 INT289241 Cish Regulation of Il6 1 0.03 0.85 0.18 64.44
86 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34 63.88
87 INT172137 IL11 Negative_regulation of Gene_expression of TNF 1 0.09 0.73 0.47 63.72
88 INT169570 Binding of ROS1 and TRPV1 3 0.33 3.07 1.89 61.68
89 INT327322 Mapkapk2 Regulation of Il6 1 0.02 0.26 0.13 60.80
90 INT300545 Il6 Positive_regulation of Gene_expression of Il1r1 1 0.02 0.42 0.11 59.96
91 INT243678 Binding of GSR and Ugcg 2 0.03 2.84 0.83 59.48
92 INT188524 Il1a Positive_regulation of Ptges 1 0.00 0.31 0.28 59.48
93 INT327306 Mapk6 Positive_regulation of Mapk14 Positive_regulation of Positive_regulation of IL8 1 0.00 0.3 0.16 58.48
94 INT327318 Mapk14 Regulation of Localization of Elavl1 1 0.09 0.42 0.13 58.28
95 INT236365 Binding of CD40LG and IL6 3 0.20 4.16 1.42 58.16
96 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88 58.16
97 INT311987 Binding of Cd40 and Negative_regulation of Regulation of Hand1 1 0.28 0.27 0.21 57.96
98 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72 57.36
99 INT172094 Binding of Atp9a and Il27ra 1 0.01 0.98 0.4 57.20
100 INT172095 Binding of Atp9a and Trav6-3 1 0.03 0.98 0.39 57.20
101 INT188427 IL6 Positive_regulation of Pdxp 1 0.00 0.84 0.38 56.96
102 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87 56.80
103 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 56.48
104 INT172096 Binding of HLA-E and Il27ra 2 0.01 1.32 0.48 56.48
105 INT327324 Mapk6 Positive_regulation of Mapk14 1 0.01 0.29 0.15 55.68
106 INT236364 CD40LG Positive_regulation of Gene_expression of IL6 1 0.25 1.37 0.72 53.80
107 INT171897 Binding of Bmpr2 and Il1 1 0.03 0.84 0.52 51.28
108 INT74217 Oprl1 Negative_regulation of Positive_regulation of Icam1 1 0.18 0.11 0 50.00
109 INT191950 NFKB2 Regulation of Gene_expression of NOS2 1 0.08 1 0.47 49.76
110 INT191948 NFKB1 Regulation of Gene_expression of NOS2 1 0.38 1 0.47 49.28
111 INT220054 Regulation of IFN1@ Negative_regulation of Cia1 1 0.18 1.19 0.52 49.04
112 INT220055 IFN1@ Negative_regulation of Cia1 1 0.24 1.12 0.48 49.04
113 INT182054 Il18 Positive_regulation of LOH19CR1 1 0.55 0.74 0.38 47.28
114 INT182097 Binding of Il6 and Il1 4 0.07 4.67 1.55 46.72
115 INT300546 Binding of Il23a and Il1 1 0.01 0.5 0.25 46.72
116 INT182052 Il18 Positive_regulation of Col7a1 1 0.03 0.74 0.38 46.16
117 INT302837 Binding of TNFRSF10D and Trp53 1 0.01 0.98 0.28 45.68
118 INT284048 Binding of Cia1 and Vtcn1 1 0.02 1.37 0.6 45.24
119 INT289248 Il6 Positive_regulation of Gene_expression of Il21 1 0.06 0.69 0.15 42.80
120 INT300549 Il1 Regulation of Gene_expression of Irf4 1 0.01 0.63 0.33 41.28
121 INT171898 Il1rn Regulation of Gene_expression of Il1 1 0.02 0.92 0.4 40.84
122 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 37.28
123 INT320153 Negative_regulation of Binding of IL6 and IL6R 1 0.02 0.37 0.24 37.28
124 INT171896 Binding of Ifnar1 and Il1rn 1 0.00 0.81 0.54 36.24
125 INT191949 NFKB2 Positive_regulation of NOS2 1 0.05 1.16 0.31 34.12
126 INT171899 Binding of Ifnar1 and Il1 1 0.01 0.75 0.52 34.00
127 INT278697 LEF1 Negative_regulation of STAT6 1 0.00 0.44 0.78 32.00
128 INT95405 Trib3 Positive_regulation of Phosphorylation of Ephb1 3 0.08 1.33 1.89 29.12
129 INT196576 Trib3 Positive_regulation of Phosphorylation of Mapk9 1 0.02 0.5 0.85 29.12
130 INT196578 Ephb1 Positive_regulation of Phosphorylation of Mapk9 1 0.13 0.5 0.85 28.80
131 INT327313 Positive_regulation of Mapk14 Positive_regulation of Phosphorylation of Khsrp 1 0.09 0.24 0.22 26.32
132 INT224682 Mcl1 Regulation of Bak1 1 0.01 1.09 0.03 20.36
133 INT224689 Binding of Bak1 and Mcl1 1 0.01 1.09 0.03 20.36
134 INT224676 Binding of Bax and Mcl1 1 0.01 1.09 0.03 20.36
135 INT224690 Mcl1 Regulation of Bax 1 0.00 1.09 0.03 20.36
136 INT172138 IL17A Positive_regulation of Gene_expression of TNF 1 0.07 0.5 0.43 19.84
137 INT172149 IL17A Positive_regulation of Gene_expression of IL1B 1 0.01 0.5 0.43 19.20
138 INT171903 Binding of TNF and Lifr 1 0.01 0.35 0.22 18.68
139 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 17.68
140 INT289244 Binding of Il11ra1 and Il6ra 1 0.01 0.33 0.07 17.12
141 INT196584 Binding of Mapk14 and NeuN 1 0.02 0.39 0.27 16.84
142 INT289258 Binding of ABCA1 and Il6ra 1 0.00 0.33 0.07 16.64
143 INT224696 TNF Positive_regulation of Gene_expression of Mcl1 1 0.01 1.07 0.05 15.72
144 INT172144 IL4 Negative_regulation of Transcription of PLA2G4A 1 0.02 0.82 0.58 9.04
145 INT172133 IL4 Negative_regulation of Gene_expression of HMOX2 1 0.00 0.81 0.58 6.56
146 INT176477 Binding of CXCR3 and CXCL10 14 0.25 10.61 5.87 5.00
147 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 5.00
148 INT126717 Binding of Il6 and Il6st 3 0.21 3.35 2.22 5.00
149 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
150 INT89379 TNF Positive_regulation of Gene_expression of IL6 5 0.50 4.37 1.69 5.00
151 INT126718 Binding of Il6 and Il6r 3 0.09 2.33 1.49 5.00
152 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 5.00
153 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 5.00
154 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27 5.00
155 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22 5.00
156 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2 5.00
157 INT203103 ACAN Negative_regulation of Gene_expression of IL10 1 0.02 1.31 1.12 5.00
158 INT333966 Binding of Il6r and Il6st 1 0.01 1.74 1.1 5.00
159 INT176474 Binding of CXCR3 and CXCL9 3 0.22 1.9 1.05 5.00
160 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 5.00
161 INT264324 Olr614 Regulation of IL-17 1 0.02 2.3 1.03 5.00
162 INT181450 Binding of Ccr5 and Ccl3 4 0.18 2.19 1.03 5.00
163 INT228498 Il10 Negative_regulation of Hand1 1 0.03 1.4 0.99 5.00
164 INT228496 Il4 Negative_regulation of Hand1 1 0.02 1.4 0.99 5.00
165 INT228495 Il13 Negative_regulation of Hand1 1 0.01 1.4 0.98 5.00
166 INT103796 IL1B Positive_regulation of Gene_expression of SELE 2 0.08 1 0.98 5.00
167 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98 5.00
168 INT187111 TIMP2 Regulation of MMP9 1 0.23 1.47 0.97 5.00
169 INT103133 TNF Positive_regulation of Gene_expression of IL8 2 0.48 1.26 0.96 5.00
170 INT133050 TNF Positive_regulation of Gene_expression of ICAM1 3 0.67 1.91 0.94 5.00
171 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 5.00
172 INT220031 Casp3 Positive_regulation of Gene_expression of Nos3 1 0.04 0 0.92 5.00
173 INT302828 Mapkapk5 Positive_regulation of Mapk1 1 0.07 1.38 0.91 5.00
174 INT185417 Binding of ALOX5 and PLA2G2A 4 0.16 3.13 0.9 5.00
175 INT187225 Vip Negative_regulation of Gene_expression of Tnfrsf11a 1 0.27 1.92 0.87 5.00
176 INT209928 IL1B Positive_regulation of MAPK14 2 0.15 1.69 0.87 5.00
177 INT194856 Positive_regulation of Adora2b Negative_regulation of Positive_regulation of Mmp13 1 0.01 0.73 0.85 5.00
178 INT184114 Tlr4 Positive_regulation of Socs3 2 0.65 1.14 0.83 5.00
179 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83 5.00
180 INT278696 MTX1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83 5.00
181 INT187226 Vip Positive_regulation of Gene_expression of Il1rn 1 0.04 0.96 0.82 5.00
182 INT187232 Vip Positive_regulation of Gene_expression of Il10 1 0.16 0.95 0.81 5.00
183 INT302831 Binding of Creb1 and Mapkapk5 1 0.07 1.3 0.79 5.00
184 INT188531 Binding of TNF and PDXK 1 0.03 1.99 0.78 5.00
185 INT258798 Binding of NR3C1 and HSP90AA1 1 0.01 1.09 0.78 5.00
186 INT187229 Binding of Tnfsf11 and Insrr 1 0.00 2.06 0.78 5.00
187 INT184116 Il10 Positive_regulation of Stat3 2 0.18 1.15 0.77 5.00
188 INT346234 MAP2K6 Positive_regulation of MAPK14 1 0.44 1.65 0.77 5.00
189 INT173112 IL1B Positive_regulation of Gene_expression of VCAM1 2 0.43 1.34 0.76 5.00
190 INT149192 TNF Positive_regulation of Gene_expression of VCAM1 3 0.57 1.4 0.76 5.00
191 INT176473 IL10 Positive_regulation of Gene_expression of PECAM1 1 0.05 1.1 0.75 5.00
192 INT176479 IL17A Positive_regulation of Gene_expression of TIMP1 1 0.02 1.33 0.74 5.00
193 INT182044 Binding of Proc and IgG 1 0.00 2.38 0.74 5.00
194 INT228499 Binding of FAS and Fasl 1 0.15 2.75 0.73 5.00
195 INT327994 Il6 Positive_regulation of Gene_expression of ROS1 1 0.05 0.55 0.73 5.00
196 INT220033 Casp3 Positive_regulation of Gene_expression of Nos1 1 0.05 0.52 0.72 5.00
197 INT172134 Binding of IL6 and IL15 2 0.01 1.18 0.72 5.00
198 INT172147 Binding of IL15 and TNF 2 0.05 1.19 0.72 5.00
199 INT187231 Negative_regulation of Binding of Tnfrsf11a and Tnfsf11 1 0.18 1.8 0.71 5.00
200 INT184125 Il12a Positive_regulation of Stat4 2 0.11 1.04 0.7 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Experimental Arthritis. They are ordered first by their pain relevance and then by number of times they were reported in Experimental Arthritis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT80972 Gene_expression of Tp53 104 0.78 102.74 16.02 100.00
2 INT169997 Positive_regulation of Gene_expression of Tp53 37 0.70 47.3 9.85 100.00
3 INT178903 Gene_expression of SNRPF 1 0.42 6.73 3.94 100.00
4 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 100.00
5 INT166203 Positive_regulation of Cia1 62 0.43 75.94 31.37 100.00
6 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 100.00
7 INT2649 Regulation of Calca 433 0.62 146.05 330.95 100.00
8 INT176453 Negative_regulation of Cia1 23 0.14 28.27 12.33 100.00
9 INT182031 Gene_expression of Cia1 38 0.24 46.37 19.64 100.00
10 INT32184 Negative_regulation of Col2a1 9 0.42 3.05 1.43 100.00
11 INT4562 Regulation of Slc6a2 8 0.53 1.45 3.43 100.00
12 INT187091 Localization of Cia1 10 0.27 11.11 4.4 100.00
13 INT32183 Positive_regulation of Negative_regulation of Col2a1 2 0.46 1.01 0.49 100.00
14 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 100.00
15 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 100.00
16 INT65260 Positive_regulation of Col7a1 95 0.69 61.73 18.42 100.00
17 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41 100.00
18 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 100.00
19 INT56450 Negative_regulation of Gene_expression of Icam1 33 0.52 27.21 10.15 100.00
20 INT174851 Positive_regulation of COL5A2 46 0.54 12.73 5.48 100.00
21 INT264337 Positive_regulation of NCOA5 4 0.03 4.28 1.23 100.00
22 INT187094 Regulation of Negative_regulation of Cia1 1 0.12 1.9 0.77 100.00
23 INT111335 Gene_expression of HSPD1 57 0.75 55.51 10.38 99.98
24 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98 99.98
25 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.96
26 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.96
27 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 99.96
28 INT184305 Gene_expression of Comp 53 0.77 31.66 2.2 99.96
29 INT184313 Positive_regulation of Comp 4 0.55 4.23 1.24 99.96
30 INT184307 Positive_regulation of Gene_expression of Comp 6 0.50 2.48 0.59 99.96
31 INT22900 Positive_regulation of Cd4 126 0.67 82.77 16.43 99.92
32 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 99.88
33 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 99.88
34 INT204461 Localization of Scn10a 4 0.31 2.58 0.79 99.88
35 INT264318 Gene_expression of Olr614 1 0.03 4.2 1.71 99.88
36 INT264314 Positive_regulation of Gene_expression of Olr614 1 0.02 1.44 0.43 99.88
37 INT103900 Positive_regulation of ERCC2 7 0.58 3.47 1.78 99.86
38 INT188422 Negative_regulation of Pdxk 1 0.01 8.91 3.73 99.84
39 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.84
40 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 99.84
41 INT20129 Regulation of Il1 53 0.53 44.14 19.89 99.84
42 INT48406 Gene_expression of Icam1 277 0.78 238.28 81.71 99.84
43 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 99.82
44 INT69311 Gene_expression of Scn10a 31 0.78 15.54 14.64 99.80
45 INT220695 Positive_regulation of Gene_expression of Scn10a 2 0.10 2.06 0.7 99.80
46 INT188424 Positive_regulation of Localization of Pdxk 1 0.01 0.95 0.48 99.80
47 INT278717 Gene_expression of STAT4 1 0.39 1.17 1.26 99.72
48 INT294150 Regulation of Gene_expression of PTPRC 6 0.32 3.3 0.88 99.72
49 INT97701 Phosphorylation of Mapk14 191 0.82 115.33 100.46 99.68
50 INT616 Regulation of Orm1 4 0.38 1.72 1.08 99.68
51 INT258795 Binding of Cux1 3 0.30 1.05 0.51 99.68
52 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 99.64
53 INT113420 Positive_regulation of Gene_expression of IL18 22 0.69 19.96 5.53 99.64
54 INT128752 Negative_regulation of Localization of Esr1 11 0.43 4.8 1.23 99.60
55 INT178902 Regulation of Pla2g3 1 0.02 1.04 0.63 99.58
56 INT103899 Gene_expression of ERCC2 14 0.65 7.85 5.49 99.56
57 INT176386 Positive_regulation of Gene_expression of TH1L 14 0.32 9.17 3.4 99.56
58 INT4683 Negative_regulation of PDXK 17 0.55 12.81 4.39 99.52
59 INT72651 Gene_expression of TH1L 114 0.75 80.15 35.15 99.50
60 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.44
61 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 99.44
62 INT48896 Positive_regulation of Gene_expression of Il10 73 0.70 43.14 35.5 99.42
63 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.40
64 INT6294 Regulation of Gene_expression of Oprm1 28 0.62 6.77 22.79 99.40
65 INT21324 Binding of Gm5195 1 0.10 0.26 0.96 99.40
66 INT188417 Localization of Pdxk 1 0.01 4.09 1.92 99.38
67 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 99.36
68 INT27415 Negative_regulation of Positive_regulation of Got1 15 0.51 10.99 5.14 99.36
69 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 99.36
70 INT202417 Gene_expression of Gata3 16 0.61 7.84 4.12 99.32
71 INT202419 Positive_regulation of Gene_expression of Gata3 6 0.52 5.47 2.6 99.32
72 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 99.28
73 INT278712 Negative_regulation of STAT4 1 0.21 1.22 1.29 99.28
74 INT118095 Regulation of COMP 7 0.43 9.69 3.33 99.28
75 INT2038 Localization of Esr1 104 0.79 40.12 13.27 99.26
76 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 99.16
77 INT49850 Negative_regulation of PDE4A 105 0.58 76.91 26.59 99.16
78 INT59 Regulation of Adrb1 25 0.42 8.32 9.78 99.16
79 INT6852 Localization of TNF 883 0.81 705.95 270.84 99.12
80 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 99.12
81 INT86950 Negative_regulation of Gene_expression of Il10 26 0.42 18.92 12.73 99.08
82 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27 99.08
83 INT6293 Gene_expression of Oprm1 312 0.78 48.73 215.61 99.04
84 INT48907 Positive_regulation of Gene_expression of Oprm1 53 0.69 8.55 33.52 99.04
85 INT234 Binding of Alb 151 0.48 52.34 32.97 99.04
86 INT89664 Negative_regulation of Adora2a 11 0.59 7.81 5.07 99.02
87 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.00
88 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.00
89 INT103699 Negative_regulation of IL15 5 0.24 2.42 1.12 99.00
90 INT6481 Binding of TNF 624 0.48 510.2 214.82 98.98
91 INT3971 Positive_regulation of Alb 175 0.70 98.46 36.45 98.96
92 INT89368 Positive_regulation of Tf 7 0.34 3.62 0.83 98.96
93 INT71531 Positive_regulation of Col4a4 5 0.42 2.49 2.51 98.96
94 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 98.96
95 INT89363 Positive_regulation of Ahsg 2 0.11 1.11 0.63 98.96
96 INT16188 Positive_regulation of Pls1 4 0.19 3.07 2.85 98.96
97 INT89359 Positive_regulation of A1i3 1 0.03 0.84 0.36 98.96
98 INT89365 Positive_regulation of Serpina3k 1 0.09 0.83 0.36 98.96
99 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 98.96
100 INT89364 Positive_regulation of Serpina1f 1 0.03 0.8 0.34 98.96
101 INT8237 Positive_regulation of Kng1 16 0.69 4.41 2.12 98.96
102 INT89366 Positive_regulation of Klk1c8 2 0.18 2.18 1.11 98.96
103 INT41639 Positive_regulation of A2m 7 0.46 4.52 1.74 98.96
104 INT3401 Positive_regulation of Hp 22 0.69 16.33 7.97 98.96
105 INT9660 Regulation of TNF 363 0.62 312.94 139.99 98.94
106 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 98.92
107 INT13267 Binding of Pgr 15 0.40 3.5 2.22 98.92
108 INT189287 Binding of Atp6v1e1 7 0.19 6.9 1.14 98.92
109 INT4422 Positive_regulation of Gene_expression of Alb 30 0.50 18.56 6.12 98.90
110 INT15725 Positive_regulation of Fn1 17 0.67 14.93 8.03 98.90
111 INT187618 Localization of Ppara 13 0.70 6.91 3.09 98.88
112 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 98.88
113 INT159009 Regulation of Il6st 2 0.18 2 1.41 98.84
114 INT264336 Protein_catabolism of NCOA5 1 0.03 0.9 0.24 98.84
115 INT188691 Negative_regulation of Binding of Cd40 3 0.42 2.49 1.31 98.80
116 INT178201 Negative_regulation of Binding of Cd40lg 2 0.33 2.92 0.64 98.80
117 INT110809 Gene_expression of Mmp1 20 0.75 18 14.49 98.80
118 INT187616 Negative_regulation of Gene_expression of Mmp1 3 0.44 2.37 1.73 98.80
119 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 98.80
120 INT102987 Regulation of MMP3 23 0.60 9.35 9.54 98.72
121 INT18489 Binding of Man2a2 59 0.48 11.27 29.38 98.72
122 INT12484 Binding of Drd2 45 0.48 15.17 24.72 98.72
123 INT18148 Binding of Htr1f 4 0.47 2.05 3.23 98.72
124 INT27153 Regulation of Aldh5a1 1 0.44 0.41 0.63 98.68
125 INT2774 Binding of Crp 241 0.48 195.89 44.39 98.68
126 INT133156 Binding of Cd40 77 0.48 45.92 13.77 98.64
127 INT85965 Binding of Cd40lg 26 0.45 16.76 4.52 98.64
128 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 98.60
129 INT261242 Binding of Tmed4 7 0.04 3.56 1.07 98.60
130 INT150022 Positive_regulation of Il17a 69 0.64 70.04 21.87 98.60
131 INT228469 Negative_regulation of Il17a 19 0.54 18.76 6.43 98.60
132 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 98.56
133 INT612 Positive_regulation of Orm1 15 0.68 5.24 6.73 98.54
134 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 98.52
135 INT71592 Negative_regulation of Gene_expression of Oprm1 11 0.58 4.03 10.37 98.52
136 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 98.52
137 INT35380 Binding of Fn1 8 0.35 4.84 2.23 98.48
138 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 98.44
139 INT98490 Localization of Ean5 1 0.22 1.23 0.61 98.44
140 INT12720 Positive_regulation of Il1 246 0.70 195.97 72.05 98.42
141 INT230497 Positive_regulation of Transcription of Il1 2 0.40 2.77 0.77 98.42
142 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 98.42
143 INT94952 Positive_regulation of Mapk14 305 0.70 197.83 186.61 98.40
144 INT8908 Negative_regulation of Defb22 2 0.04 0.98 2.68 98.40
145 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 98.36
146 INT8424 Positive_regulation of Gene_expression of Vip 11 0.70 8.01 8.31 98.36
147 INT323837 Negative_regulation of TT-DTH 1 0.01 1.04 0.57 98.36
148 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29 98.32
149 INT7909 Positive_regulation of Positive_regulation of Got1 8 0.49 6.44 3.06 98.28
150 INT8824 Regulation of Vip 95 0.62 15.7 43.63 98.20
151 INT59321 Transcription of Il1 13 0.50 9.73 2.68 98.18
152 INT186284 Binding of Il27 3 0.16 1.85 0.78 98.16
153 INT220120 Regulation of RGD1563494 2 0.09 3.41 1.15 98.12
154 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 98.10
155 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 98.08
156 INT289775 Negative_regulation of Comp 4 0.41 5.69 2.2 98.08
157 INT49995 Positive_regulation of Gene_expression of Tnf 187 0.70 125.07 70.54 98.08
158 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 98.08
159 INT91906 Regulation of Gene_expression of Il10 13 0.58 8.92 7.06 98.08
160 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 98.04
161 INT615 Regulation of Alb 66 0.62 33.43 15.33 98.04
162 INT184271 Positive_regulation of Gene_expression of HMGB1 7 0.41 6.17 1.53 98.04
163 INT125840 Positive_regulation of Binding of Col2a1 1 0.43 1.21 0.45 98.00
164 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 97.96
165 INT16917 Positive_regulation of Gene_expression of IL36RN 8 0.12 6.17 1.56 97.92
166 INT19775 Localization of Il1 183 0.78 145.5 50.91 97.90
167 INT52800 Negative_regulation of Gene_expression of Tnf 142 0.59 92.27 55.47 97.84
168 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 97.84
169 INT13354 Transcription of TNF 108 0.72 85.81 42.32 97.84
170 INT73905 Transcription of IL1RN 10 0.71 9.16 5.04 97.84
171 INT70387 Negative_regulation of Positive_regulation of Jun 14 0.37 3.76 3.23 97.84
172 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 97.76
173 INT14575 Positive_regulation of Ppt1 60 0.70 9.97 27.4 97.76
174 INT74286 Regulation of Il10 42 0.44 28.06 19.44 97.64
175 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 97.60
176 INT204550 Regulation of Cia1 6 0.23 9.7 4.23 97.60
177 INT93598 Positive_regulation of Gene_expression of Zic5 1 0.00 0.57 1.26 97.60
178 INT93599 Gene_expression of Zic5 1 0.00 0.57 1.25 97.60
179 INT142464 Gene_expression of Socs3 58 0.77 52.04 15.34 97.52
180 INT142462 Positive_regulation of Gene_expression of Socs3 23 0.68 23.27 8.27 97.52
181 INT115579 Positive_regulation of Positive_regulation of Il10 7 0.68 4.82 2.91 97.52
182 INT6474 Positive_regulation of Gene_expression of IL1RN 34 0.69 21.87 10.99 97.52
183 INT184269 Gene_expression of HMGB1 51 0.77 42.96 4.55 97.52
184 INT6796 Positive_regulation of Jun 165 0.70 37.18 49.64 97.44
185 INT110494 Gene_expression of Galp 1 0.78 3.56 1.35 97.40
186 INT110495 Positive_regulation of Gene_expression of Galp 1 0.70 3.14 1.33 97.40
187 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 97.36
188 INT4758 Positive_regulation of Localization of Calca 557 0.70 138.55 411.04 97.36
189 INT137135 Gene_expression of THBS1 28 0.75 11.55 2.45 97.28
190 INT87687 Positive_regulation of Trpv1 409 0.70 210.24 257.59 97.28
191 INT30117 Gene_expression of Calm1 18 0.71 17.45 13.18 97.24
192 INT76707 Negative_regulation of Gene_expression of Ptger3 6 0.20 2.56 3.73 97.24
193 INT23122 Gene_expression of Ptger3 31 0.72 11.94 11.37 97.24
194 INT43486 Positive_regulation of Ifng 52 0.69 32.71 24.77 97.24
195 INT140818 Positive_regulation of Positive_regulation of Ifng 2 0.47 4.2 2.06 97.24
196 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 97.24
197 INT181344 Gene_expression of Ccr6 28 0.61 24.34 9.78 97.22
198 INT320188 Regulation of Gene_expression of Calm1 2 0.39 2.48 1.39 97.20
199 INT226443 Binding of STAT4 3 0.45 3.81 2.06 97.20
200 INT2542 Localization of Calca 2008 0.81 518.3 1408.65 97.16
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