D:Facies

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pChart

Disease Term
Synonyms None
Documents 93
Hot Single Events 19
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Facies. They are ordered first by their relevance to Facies and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT207776 Binding of FKBP1A and RYR1 1 0.05 0.59 0.12 20.72
2 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
3 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
4 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
5 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
6 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
7 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
8 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
9 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
10 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
11 INT207783 Binding of MRC1 and Ap3d1 1 0.00 2.54 0.22 5.00
12 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
13 INT207784 Ap3d1 Regulation of CACNA1S 1 0.05 0.97 0.16 5.00
14 INT239081 Binding of GH1 and MAS1 1 0.03 1.41 0.15 5.00
15 INT340744 CSF2 Regulation of BDNF 1 0.13 1.45 0.14 5.00
16 INT340742 Positive_regulation of CSF2 Regulation of BDNF 1 0.22 1.46 0.14 5.00
17 INT207785 Binding of RYR1 and Ap3d1 1 0.06 3.24 0.13 5.00
18 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
19 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 5.00
20 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09 5.00
21 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 5.00
22 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
23 INT196592 Binding of CFD and GHRH 1 0.02 1.88 0.07 5.00
24 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
25 INT279889 Il6 Regulation of Socs3 1 0.21 0.17 0.05 5.00
26 INT199665 Binding of Fxn and Lamtor3 1 0.00 0.16 0.03 5.00
27 INT279885 Ctcf Regulation of H19 1 0.12 0 0 5.00
28 INT279891 Shbdp1 Negative_regulation of PCDHB@ 1 0.01 0.09 0 5.00
29 INT239080 Binding of PPY and KAT2B 1 0.02 2.38 0 5.00
30 INT279886 Shbdp1 Negative_regulation of Pcdhb1 1 0.10 0.09 0 5.00
31 INT340743 Negative_regulation of CSF2 Positive_regulation of ZNF807 1 0.00 1.77 0 5.00
32 INT340745 CSF2 Positive_regulation of ZNF807 1 0.00 1.76 0 5.00
33 INT279884 Nipbl Regulation of Transcription of Pcdhb1 1 0.25 0.05 0 5.00
34 INT279892 Shbdp1 Negative_regulation of Gene_expression of PCDHB@ 1 0.01 0.09 0 5.00
35 INT279888 Binding of Rec8 and Nipbl 1 0.01 0.81 0 5.00
36 INT279890 Nipbl Regulation of Gene_expression of PCDHB@ 1 0.07 0.1 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Facies. They are ordered first by their pain relevance and then by number of times they were reported in Facies. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.36
2 INT921 Regulation of GH1 172 0.60 52.88 51.04 97.50
3 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 96.24
4 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 96.04
5 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 95.84
6 INT995 Negative_regulation of Arsb 1 0.50 1.48 0.16 94.04
7 INT16869 Positive_regulation of Prl 24 0.70 15.7 7.63 93.28
8 INT19900 Binding of GHRH 22 0.37 5.75 5 93.24
9 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 91.16
10 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 89.92
11 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 87.68
12 INT6947 Negative_regulation of Gene_expression of POMC 37 0.59 10.32 14.14 87.68
13 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 85.96
14 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 84.24
15 INT255194 Binding of Fbn1 2 0.35 4.26 0.34 83.48
16 INT207777 Binding of Ap3d1 1 0.07 14.51 1.91 83.28
17 INT24974 Negative_regulation of Naglu 5 0.42 2.68 0.9 83.24
18 INT1931 Positive_regulation of Gene_expression of POMC 116 0.70 37.26 38.67 81.12
19 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 80.28
20 INT153233 Negative_regulation of Ids 5 0.40 2.1 0.12 79.76
21 INT21855 Gene_expression of Ap3d1 4 0.32 12.21 4.66 75.00
22 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98 73.16
23 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 70.92
24 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 70.92
25 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 70.92
26 INT263492 Positive_regulation of Regulation of Hand2 3 0.19 4.76 0.21 70.92
27 INT96693 Binding of COL2A1 45 0.46 37.11 2.61 70.56
28 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 70.52
29 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 70.52
30 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 70.52
31 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 69.84
32 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 69.48
33 INT141785 Negative_regulation of GALNS 3 0.59 1.92 0.09 64.72
34 INT199656 Binding of Pnkp 1 0.07 1.36 0.07 64.68
35 INT332543 Gene_expression of Atp2b2 1 0.04 1.81 0 57.76
36 INT86023 Transcription of PPARA 60 0.66 25.8 5.7 53.16
37 INT77281 Negative_regulation of HIVEP1 132 0.49 102.78 5.36 52.68
38 INT23468 Gene_expression of Fbn1 7 0.76 8.04 0.76 52.52
39 INT279838 Protein_catabolism of Rec8 1 0.02 0.81 0 51.28
40 INT184434 Localization of Adamts1 5 0.63 1.95 0.41 49.36
41 INT315626 Localization of DLEU1 2 0.35 4.17 0.07 48.40
42 INT327714 Localization of CNC 1 0.10 0.79 0.09 47.76
43 INT95641 Regulation of Fbn1 3 0.45 3.67 0.91 47.60
44 INT78210 Gene_expression of MCC 7 0.65 1.8 0.98 41.92
45 INT196593 Phosphorylation of CFD 1 0.55 0.84 0.04 37.44
46 INT251821 Negative_regulation of COL11A1 3 0.42 3.45 0.16 35.84
47 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 35.08
48 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 34.76
49 INT125980 Binding of CFD 8 0.42 10.96 1.39 32.24
50 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 31.92
51 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 30.88
52 INT6508 Gene_expression of RYR1 34 0.77 11.11 2.04 29.92
53 INT252 Localization of GH1 529 0.80 227.4 122.05 29.60
54 INT133889 Gene_expression of Adamts1 78 0.76 48.05 6.58 28.88
55 INT86024 Gene_expression of PPARA 736 0.78 497.93 91.14 25.80
56 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95 24.40
57 INT279863 Localization of Pds5a 1 0.47 0.93 0 20.56
58 INT279844 Localization of Pds5b 1 0.65 0.94 0 20.56
59 INT196595 Regulation of Localization of CFD 1 0.39 2.03 0.04 13.60
60 INT196594 Localization of CFD 4 0.65 4.36 0.39 12.80
61 INT103094 Binding of PPARA 308 0.47 177.26 34.75 12.00
62 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 10.40
63 INT208561 Gene_expression of Shh 51 0.78 9.57 1.77 8.24
64 INT279849 Binding of Pds5b 1 0.32 0.93 0 5.36
65 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1 5.12
66 INT3439 Localization of Abat 1017 0.78 112.39 727.06 5.00
67 INT2909 Positive_regulation of Abat 334 0.70 62.1 256.43 5.00
68 INT9987 Gene_expression of Abat 296 0.78 95.46 226.34 5.00
69 INT2211 Negative_regulation of Abat 267 0.59 66.51 200.98 5.00
70 INT4829 Positive_regulation of Localization of Abat 199 0.55 20.91 150.48 5.00
71 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
72 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
73 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
74 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 5.00
75 INT1438 Localization of Pomc 360 0.81 101.26 116.47 5.00
76 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
77 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
78 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
79 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
80 INT86521 Gene_expression of Lpar1 167 0.78 154.61 80.35 5.00
81 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
82 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
83 INT2212 Binding of Abat 89 0.48 18.36 63.99 5.00
84 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
85 INT67614 Positive_regulation of PPARA 438 0.68 293.28 63.61 5.00
86 INT654 Localization of REN 250 0.81 75.12 47.86 5.00
87 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
88 INT12228 Positive_regulation of Gene_expression of Abat 44 0.65 17.51 40.55 5.00
89 INT80690 Positive_regulation of MAPK8 223 0.68 125.63 36.75 5.00
90 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 5.00
91 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
92 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 5.00
93 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
94 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
95 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
96 INT17825 Gene_expression of Flvcr2 44 0.68 12.58 28.08 5.00
97 INT48853 Positive_regulation of BDNF 82 0.69 43.92 27.99 5.00
98 INT2912 Positive_regulation of Positive_regulation of Abat 29 0.66 6.48 27.54 5.00
99 INT14690 Localization of CSF2 124 0.80 85.17 27.26 5.00
100 INT13995 Gene_expression of gr 96 0.74 48.21 26.54 5.00
101 INT63444 Regulation of Gene_expression of Abat 26 0.51 14.65 26.29 5.00
102 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
103 INT73625 Gene_expression of PPARG 108 0.78 104.85 21.42 5.00
104 INT101517 Negative_regulation of PPARA 168 0.57 112.24 21.41 5.00
105 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 5.00
106 INT105021 Binding of GOPC 187 0.40 60.39 20.38 5.00
107 INT31874 Negative_regulation of Gene_expression of Abat 31 0.42 12.22 20.31 5.00
108 INT23533 Gene_expression of CA2 110 0.75 30.81 19.4 5.00
109 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 5.00
110 INT15148 Gene_expression of Vip 51 0.77 25.61 18.33 5.00
111 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 5.00
112 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 5.00
113 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
114 INT93361 Gene_expression of Trp53 208 0.78 175.35 16.65 5.00
115 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
116 INT11685 Regulation of CSF2 99 0.59 58.82 15.9 5.00
117 INT1752 Negative_regulation of Ache 109 0.59 42.05 15.73 5.00
118 INT100139 Positive_regulation of Gene_expression of PPARA 160 0.63 97.78 14.53 5.00
119 INT22301 Positive_regulation of Gene_expression of CSF2 66 0.63 59.49 14.24 5.00
120 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 5.00
121 INT173505 Localization of Hand2 63 0.57 45.32 13.66 5.00
122 INT80790 Positive_regulation of Flvcr2 22 0.45 4.92 12.35 5.00
123 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
124 INT158070 Localization of Aes 23 0.65 19.93 10.9 5.00
125 INT1108 Gene_expression of PPY 58 0.75 36.57 10.76 5.00
126 INT15350 Localization of Prl 22 0.81 6.86 10.74 5.00
127 INT701 Localization of IGHE 87 0.80 40.5 10.62 5.00
128 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
129 INT17824 Positive_regulation of Gene_expression of Flvcr2 15 0.41 6.66 10.23 5.00
130 INT167964 Gene_expression of Aes 30 0.58 25.41 10.16 5.00
131 INT53063 Positive_regulation of Slc1a1 10 0.70 3.23 9.89 5.00
132 INT122584 Negative_regulation of Gene_expression of PPARA 56 0.58 37.61 9.76 5.00
133 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 5.00
134 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 5.00
135 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
136 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 5.00
137 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
138 INT108931 Negative_regulation of BDNF 38 0.59 19.61 8.84 5.00
139 INT228870 Negative_regulation of Lpar1 17 0.51 20.97 8.77 5.00
140 INT2597 Negative_regulation of ACHE 82 0.59 46.36 8.62 5.00
141 INT77249 Positive_regulation of Gene_expression of gr 24 0.67 16.09 8.17 5.00
142 INT150422 Positive_regulation of Aes 24 0.43 15.63 8 5.00
143 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 5.00
144 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 5.00
145 INT264027 Positive_regulation of Positive_regulation of Flvcr2 2 0.08 2.67 7.27 5.00
146 INT111056 Negative_regulation of Gene_expression of Flvcr2 9 0.13 4.15 7.18 5.00
147 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
148 INT75382 Negative_regulation of HSPG2 20 0.57 15.18 7.03 5.00
149 INT52132 Positive_regulation of Negative_regulation of Abat 9 0.50 0.53 7.03 5.00
150 INT52180 Binding of Aes 38 0.42 23.16 6.7 5.00
151 INT10785 Gene_expression of Prl 35 0.78 20.64 6.7 5.00
152 INT132822 Localization of IL13 26 0.67 22.85 6.66 5.00
153 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 5.00
154 INT3041 Positive_regulation of MIA3 34 0.56 21.11 6.49 5.00
155 INT38807 Negative_regulation of PLA2G6 29 0.59 10.1 6.42 5.00
156 INT95313 Gene_expression of Slc6a1 6 0.76 3.96 6.14 5.00
157 INT22128 Positive_regulation of HIVEP1 61 0.43 70.52 6.07 5.00
158 INT1126 Negative_regulation of CD79A 46 0.59 31.07 6 5.00
159 INT9683 Binding of GH1 57 0.47 21.14 5.99 5.00
160 INT91100 Binding of SPTLC1 10 0.47 12.85 5.71 5.00
161 INT38671 Positive_regulation of KRT20 62 0.53 40.17 5.6 5.00
162 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
163 INT77252 Gene_expression of Nr3c1 17 0.67 9.71 5.38 5.00
164 INT171562 Regulation of IL4 19 0.36 12.12 5.33 5.00
165 INT53184 Negative_regulation of CYP27A1 46 0.57 16.04 5.28 5.00
166 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 5.00
167 INT59555 Binding of RYR1 39 0.42 8.65 4.92 5.00
168 INT78393 Gene_expression of Adm 16 0.78 8.4 4.92 5.00
169 INT17312 Binding of HSPG2 30 0.41 33.01 4.88 5.00
170 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 5.00
171 INT90350 Gene_expression of Gast 27 0.78 14.07 4.74 5.00
172 INT111739 Negative_regulation of Npy 15 0.43 4.9 4.65 5.00
173 INT107771 Localization of HSPG2 10 0.78 8.47 4.3 5.00
174 INT146355 Negative_regulation of Aes 15 0.51 7.83 4.25 5.00
175 INT94303 Gene_expression of Upf1 44 0.04 11.62 3.87 5.00
176 INT92017 Regulation of Gene_expression of Flvcr2 3 0.18 1.69 3.75 5.00
177 INT9677 Negative_regulation of Gene_expression of GH1 46 0.48 23.32 3.68 5.00
178 INT267678 Positive_regulation of Positive_regulation of Slc1a1 1 0.07 1.34 3.65 5.00
179 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
180 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
181 INT73500 Regulation of IL13 12 0.36 10.37 3.53 5.00
182 INT168677 Negative_regulation of ACOT1 14 0.27 6.29 3.52 5.00
183 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
184 INT110245 Gene_expression of SNCA 11 0.77 8.29 3.36 5.00
185 INT1727 Gene_expression of Cndp2 22 0.74 4.28 3.34 5.00
186 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 5.00
187 INT48390 Negative_regulation of Localization of CSF2 10 0.51 7.39 3.28 5.00
188 INT15648 Positive_regulation of RYR1 30 0.67 12.03 3.26 5.00
189 INT81955 Positive_regulation of SPTLC1 12 0.70 10.25 3.12 5.00
190 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 5.00
191 INT93109 Phosphorylation of NTRK1 5 0.80 3.22 2.99 5.00
192 INT21853 Regulation of Ap3d1 3 0.10 1.4 2.95 5.00
193 INT239083 Binding of PPY 9 0.32 7.59 2.9 5.00
194 INT62487 Localization of HIVEP1 35 0.73 36.24 2.72 5.00
195 INT24712 Positive_regulation of Ap3d1 18 0.54 8.58 2.71 5.00
196 INT115300 Negative_regulation of Napa 7 0.23 1 2.68 5.00
197 INT100144 Negative_regulation of Positive_regulation of PPARA 17 0.49 12.71 2.68 5.00
198 INT77250 Positive_regulation of Gene_expression of Nr3c1 4 0.44 3.32 2.64 5.00
199 INT93207 Negative_regulation of Cyp4a3 11 0.36 4.32 2.63 5.00
200 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 5.00
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