D:Gingival Hyperplasia

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pChart

Disease Term
Synonyms Gingival Hyperplasias, Hyperplasia Gingival, Hyperplasias Gingival
Documents 56
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Gingival Hyperplasia. They are ordered first by their relevance to Gingival Hyperplasia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
2 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
3 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
4 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
5 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 5.00
6 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
7 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
8 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
9 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05 5.00
10 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04 5.00
11 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03 5.00
12 INT327451 HTN1 Positive_regulation of Adra1a 1 0.00 1.36 0.03 5.00
13 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03 5.00
14 INT293368 Binding of CSH1 and Ppia 1 0.00 0.19 0.03 5.00
15 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0 5.00
16 INT293357 RORC Regulation of PPP2R4 1 0.00 0 0 5.00
17 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0 5.00
18 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0 5.00
19 INT293362 CSH1 Negative_regulation of Gene_expression of IL2 1 0.01 0.12 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Gingival Hyperplasia. They are ordered first by their pain relevance and then by number of times they were reported in Gingival Hyperplasia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT10059 Binding of CSH1 17 0.35 5.28 3.37 99.62
2 INT25797 Positive_regulation of OR2AL1P 5 0.09 5.14 0.99 94.68
3 INT4395 Positive_regulation of CSH1 20 0.50 6.27 1.52 78.68
4 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 78.32
5 INT11807 Gene_expression of Il2 266 0.78 112 64.97 74.72
6 INT11804 Positive_regulation of Gene_expression of Il2 70 0.70 33 21.63 74.72
7 INT21532 Negative_regulation of Gene_expression of Il2 47 0.59 20.43 16.96 74.72
8 INT8339 Negative_regulation of GC 12 0.57 4.9 1.37 67.28
9 INT84944 Regulation of Negative_regulation of GC 1 0.44 1 0.1 67.28
10 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 49.76
11 INT1645 Negative_regulation of CSH1 20 0.42 1.71 3.7 31.08
12 INT240519 Regulation of Scn8a 3 0.06 0.9 0.71 20.20
13 INT13539 Gene_expression of LTA 39 0.62 22.55 8.07 10.96
14 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
15 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
16 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 5.00
17 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 5.00
18 INT546 Binding of ALB 311 0.48 85.98 60.14 5.00
19 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 5.00
20 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 5.00
21 INT163134 Gene_expression of ACR 78 0.65 30.39 38.48 5.00
22 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 5.00
23 INT4403 Binding of CYP2B6 113 0.48 21.17 33.83 5.00
24 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 5.00
25 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
26 INT15796 Regulation of IL2 66 0.61 25.43 20.62 5.00
27 INT51014 Transcription of IL2 42 0.71 21.56 12.7 5.00
28 INT195226 Positive_regulation of ACR 23 0.26 7.85 12.62 5.00
29 INT5057 Negative_regulation of Gene_expression of IFNG 23 0.58 8.33 12.3 5.00
30 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 5.00
31 INT36287 Binding of CD4 96 0.47 58.93 11.88 5.00
32 INT15305 Positive_regulation of Mtor 51 0.67 8.28 11 5.00
33 INT73504 Binding of CD28 35 0.45 15.99 10.04 5.00
34 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
35 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
36 INT22383 Binding of IL2 59 0.48 39.06 8.56 5.00
37 INT8637 Negative_regulation of Dbp 112 0.50 33.28 8.4 5.00
38 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 5.00
39 INT30777 Negative_regulation of SELL 20 0.56 18.05 7.32 5.00
40 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
41 INT760 Negative_regulation of Scn8a 11 0.42 1.65 5.6 5.00
42 INT21103 Gene_expression of Dbp 48 0.61 22.6 5.59 5.00
43 INT171562 Regulation of IL4 19 0.36 12.12 5.33 5.00
44 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 5.00
45 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 5.00
46 INT60575 Binding of Fkbp1a 9 0.26 2.09 4.46 5.00
47 INT21406 Negative_regulation of Gene_expression of IgG 20 0.41 9.36 3.58 5.00
48 INT51848 Transcription of TGFB1 17 0.69 9.57 3.53 5.00
49 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29 5.00
50 INT125237 Negative_regulation of Gene_expression of CD40LG 16 0.54 9.9 3.27 5.00
51 INT36286 Binding of Cd3e 33 0.36 10.11 3.21 5.00
52 INT77226 Phosphorylation of Eif4ebp1 36 0.09 6.39 2.91 5.00
53 INT22831 Negative_regulation of Positive_regulation of IL2 7 0.55 1.7 2.62 5.00
54 INT141367 Negative_regulation of Transcription of IL2 9 0.32 2.07 2.43 5.00
55 INT258404 Positive_regulation of Gene_expression of ACR 4 0.28 1.08 2.24 5.00
56 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 5.00
57 INT43900 Gene_expression of RASA1 13 0.58 12 2.03 5.00
58 INT78960 Binding of SOAT1 9 0.36 2.56 1.92 5.00
59 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87 5.00
60 INT62692 Localization of Nanog 3 0.73 0.82 1.85 5.00
61 INT74824 Positive_regulation of Transcription of TGFB1 6 0.67 2.58 1.84 5.00
62 INT181720 Regulation of IL15 9 0.20 3.65 1.79 5.00
63 INT40322 Binding of Pnp 12 0.38 11.13 1.78 5.00
64 INT217070 Gene_expression of Acsm3 8 0.25 6.27 1.75 5.00
65 INT278981 Negative_regulation of JAK3 5 0.46 2.12 1.69 5.00
66 INT85411 Regulation of IL9 4 0.10 0.85 1.65 5.00
67 INT181963 Regulation of IL7 7 0.49 3.56 1.61 5.00
68 INT88746 Positive_regulation of Transcription of IL2 7 0.51 2.14 1.6 5.00
69 INT110201 Positive_regulation of Sbp 10 0.49 5.25 1.55 5.00
70 INT148026 Positive_regulation of Pik3cg 4 0.45 0.54 1.46 5.00
71 INT14916 Binding of RASA1 15 0.37 13.64 1.44 5.00
72 INT2824 Positive_regulation of HTN1 10 0.40 10.41 1.4 5.00
73 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 5.00
74 INT147213 Negative_regulation of Gene_expression of Dbp 5 0.34 2.88 1.16 5.00
75 INT103699 Negative_regulation of IL15 5 0.24 2.42 1.12 5.00
76 INT154057 Gene_expression of Ear1 14 0.41 9.72 1.12 5.00
77 INT51264 Positive_regulation of TXK 21 0.54 10.69 1.1 5.00
78 INT142777 Phosphorylation of PPP2R4 2 0.61 1.03 1.07 5.00
79 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07 5.00
80 INT188398 Positive_regulation of IL15 8 0.19 4.64 1.06 5.00
81 INT278975 Gene_expression of JAK3 3 0.52 1.03 0.97 5.00
82 INT198049 Positive_regulation of JAK2 16 0.58 5.35 0.96 5.00
83 INT226480 Positive_regulation of JAK3 4 0.45 0.96 0.95 5.00
84 INT230251 Binding of FKBP1A 6 0.28 2.24 0.94 5.00
85 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 5.00
86 INT100458 Positive_regulation of LTA 11 0.49 6.55 0.8 5.00
87 INT199433 Negative_regulation of LTA 5 0.17 3.84 0.74 5.00
88 INT77223 Regulation of Eif4ebp1 6 0.03 1.32 0.7 5.00
89 INT19606 Negative_regulation of Ear1 3 0.22 3.25 0.61 5.00
90 INT164465 Negative_regulation of Sbp 12 0.33 10.31 0.56 5.00
91 INT73524 Positive_regulation of Ear1 7 0.27 4.82 0.54 5.00
92 INT226429 Regulation of IL21 2 0.04 0.74 0.49 5.00
93 INT264192 Positive_regulation of Gene_expression of CTLA4 6 0.43 2.06 0.45 5.00
94 INT189240 Binding of ORM2 2 0.23 0.75 0.31 5.00
95 INT249123 Binding of Mtor 9 0.36 0.57 0.3 5.00
96 INT190676 Binding of Fkbp1a 15 0.36 3.11 0.28 5.00
97 INT234410 Binding of ISG20 4 0.22 1.66 0.26 5.00
98 INT293346 Binding of JAK3 1 0.12 0.34 0.26 5.00
99 INT293350 Regulation of Binding of IL2 2 0.22 0.87 0.23 5.00
100 INT293351 Negative_regulation of Regulation of IL15 1 0.04 0.34 0.22 5.00
101 INT161779 Positive_regulation of Gene_expression of Ear1 3 0.27 1.91 0.22 5.00
102 INT129762 Binding of HTN1 5 0.03 5.68 0.19 5.00
103 INT285702 Negative_regulation of Tpmt 2 0.28 1.4 0.19 5.00
104 INT211098 Negative_regulation of Msra 1 0.01 1.36 0.16 5.00
105 INT293345 Negative_regulation of Binding of FKBP1A 1 0.02 0.19 0.13 5.00
106 INT293340 Negative_regulation of Negative_regulation of JAK1 1 0.02 0.34 0.1 5.00
107 INT293337 Phosphorylation of CSH1 1 0.11 0.11 0.1 5.00
108 INT211097 Negative_regulation of Binding of Pnp 1 0.08 1.27 0.08 5.00
109 INT293352 Negative_regulation of Gene_expression of GMPS 1 0.01 0.12 0.07 5.00
110 INT293349 Gene_expression of GMPS 1 0.01 0.11 0.06 5.00
111 INT273506 Gene_expression of IMPDH1 5 0.18 0.45 0.06 5.00
112 INT273496 Negative_regulation of GMPS 3 0.03 0.43 0.05 5.00
113 INT165394 Regulation of HTN1 2 0.00 2.43 0.05 5.00
114 INT285701 Positive_regulation of Tpmt 1 0.33 0.57 0.04 5.00
115 INT293341 Binding of FCGRT 1 0.01 0 0.04 5.00
116 INT293344 Phosphorylation of RORC 1 0.04 0 0 5.00
117 INT211096 Positive_regulation of Tpmt 1 0.30 0.21 0 5.00
118 INT293342 Regulation of PPP2R4 1 0.03 0 0 5.00
119 INT293348 Negative_regulation of Positive_regulation of IL15 1 0.04 0.12 0 5.00
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