D:Growth Problems

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pChart

Disease Term
Synonyms Problem With Growth, SHORT STATURE
Documents 376
Hot Single Events 200
Hot Interactions 17

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Growth Problems. They are ordered first by their relevance to Growth Problems and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT328302 Gene_expression of GHS Positive_regulation of Gene_expression of GH1 1 0.03 0.17 0.08 99.50
2 INT328303 Gene_expression of GHS Positive_regulation of Gene_expression of GHRH 1 0.09 0.19 0.04 99.20
3 INT24869 GAL Regulation of Localization of Gh 1 0.19 0.4 0.51 98.92
4 INT124732 Gh Regulation of Positive_regulation of IGFBP3 1 0.00 0.24 0.08 96.36
5 INT97188 Gh Positive_regulation of Localization of Igf1 1 0.02 0.54 0.25 95.08
6 INT68482 Cga Regulation of Gh 1 0.00 1.89 0.31 95.04
7 INT68479 Gnrh1 Regulation of Lhb 1 0.00 1.58 0.25 92.84
8 INT181998 TNFRSF11B Negative_regulation of Gene_expression of CTSK 1 0.07 1.98 0.27 89.84
9 INT75355 Negative_regulation of GCG Regulation of Gh 1 0.01 1.26 0.18 88.92
10 INT75356 GCG Regulation of Gh 1 0.01 1.25 0.18 88.92
11 INT328311 Binding of GH1 and GHS 1 0.02 0.14 0.09 88.68
12 INT20030 Negative_regulation of SST Positive_regulation of Ghrh 1 0.01 0.16 0.23 86.88
13 INT20031 Negative_regulation of SST Positive_regulation of Gh 1 0.00 0.16 0.23 86.88
14 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 85.88
15 INT184464 Gtf3a Positive_regulation of Adamts1 1 0.01 0.87 0.17 80.88
16 INT184467 Gtf3a Positive_regulation of Transcription of Adamts1 1 0.01 0.87 0.17 80.88
17 INT328304 POMC Positive_regulation of Localization of CRH 1 0.07 0.22 0.03 80.80
18 INT13729 GHRH Positive_regulation of Localization of GH1 13 0.62 0.59 3.2 77.36
19 INT184458 Il17a Positive_regulation of Transcription of Adamts1 1 0.05 0.87 0.18 75.24
20 INT73167 Regulation of Lhb Positive_regulation of Gh 1 0.00 0.48 0.1 74.56
21 INT73168 Lhb Positive_regulation of Gh 2 0.00 0.95 0.2 74.00
22 INT73165 Gh Positive_regulation of Prl 2 0.00 0.95 0.2 74.00
23 INT52562 Lhb Positive_regulation of Prl 3 0.00 1.09 1.02 73.84
24 INT328312 GHS Positive_regulation of Localization of PRL 1 0.02 0.21 0.03 70.52
25 INT328309 GHS Positive_regulation of Localization of GH1 1 0.04 0.99 0.12 69.76
26 INT352392 Binding of ENOSF1 and Recql4 1 0.02 6.62 0 68.88
27 INT328374 GHRH Positive_regulation of Ghrl 1 0.13 0.26 0.13 68.24
28 INT20029 Ghrh Positive_regulation of Negative_regulation of Gh 1 0.05 0.14 0.26 64.32
29 INT328386 GHS Positive_regulation of Localization of Ghrl 1 0.10 0.88 0.17 61.64
30 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 61.64
31 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 61.64
32 INT312289 Binding of Col9a1 and Comp 1 0.09 1.38 0 61.64
33 INT312291 Binding of Comp and Matn3 1 0.06 1.37 0 61.64
34 INT132318 Ghrl Positive_regulation of Localization of GH1 5 0.32 4.49 0.84 60.08
35 INT328295 GHRH Positive_regulation of GHS 1 0.10 0.13 0.04 58.16
36 INT68480 Negative_regulation of Gnrh1 Regulation of Lhb 1 0.00 0.67 0.15 57.16
37 INT328299 Binding of GHRH and GHS 1 0.07 2.21 0.31 56.96
38 INT328301 GHRH Positive_regulation of SCG5 1 0.24 0.13 0.04 56.88
39 INT328385 Binding of GHS and Ghrl 1 0.15 1.89 0.45 55.04
40 INT11606 Regulation of Ghrh Regulation of Gh 1 0.06 0.05 0 54.40
41 INT10844 Ghrh Regulation of Gh 13 0.13 4.77 4.71 53.96
42 INT34772 GH1 Regulation of IGF1 2 0.32 0.95 0.69 50.08
43 INT34773 GH1 Regulation of IGF2 1 0.31 0.05 0.22 50.08
44 INT184460 Il1 Positive_regulation of Adamts1 1 0.04 0.99 0.4 46.40
45 INT184459 Il1 Regulation of Gene_expression of Adamts1 1 0.03 0.73 0.34 34.04
46 INT255384 Binding of AKR1C2 and DSG1 1 0.01 1.54 0 33.84
47 INT312290 Binding of Col9a1 and Matn3 1 0.02 0.65 0 28.88
48 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 20.72
49 INT207551 IGF1 Positive_regulation of Gene_expression of GH1 2 0.22 1.18 0.11 9.68
50 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15 9.12
51 INT328298 GHRH Negative_regulation of Localization of GHS 1 0.08 0.84 0 8.16
52 INT328296 GHRH Negative_regulation of Localization of GH1 1 0.03 0.84 0 8.16
53 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
54 INT35157 GH1 Regulation of GHRH 3 0.17 0.5 0.99 5.00
55 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
56 INT156667 Gh Positive_regulation of Gene_expression of Igf1 6 0.28 0.88 0.56 5.00
57 INT209885 TNFSF11 Positive_regulation of TNFRSF11A 3 0.56 3.41 0.55 5.00
58 INT328377 Binding of GAST and Ghrl 1 0.03 0.62 0.43 5.00
59 INT78444 Binding of GH1 and IGF1 4 0.16 2.82 0.37 5.00
60 INT35363 Binding of GH1 and GHRH 2 0.36 0.94 0.36 5.00
61 INT184466 Adamts1 Positive_regulation of Adamts4 1 0.13 1.03 0.3 5.00
62 INT184457 Adamts1 Positive_regulation of Positive_regulation of Adamts4 1 0.13 1.03 0.3 5.00
63 INT335027 Binding of Vdr and Fgf23 1 0.24 0.34 0.29 5.00
64 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
65 INT328378 GH1 Regulation of Gene_expression of Ghrl 1 0.02 0.39 0.25 5.00
66 INT335028 Fgf15 Positive_regulation of Fgfr4 1 0.40 0.31 0.25 5.00
67 INT231206 Binding of KCNH2 and KCNQ1 2 0.22 1.04 0.24 5.00
68 INT335015 Fgf15 Negative_regulation of Gene_expression of Cyp7a1 1 0.57 0.2 0.24 5.00
69 INT328382 Positive_regulation of Ghrl Positive_regulation of Localization of INS 1 0.03 1.08 0.23 5.00
70 INT207845 Binding of INS and Hypism 3 0.04 2.88 0.22 5.00
71 INT335021 Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.53 1.49 0.21 5.00
72 INT335025 Gm7647 Positive_regulation of Gene_expression of Fgf21 1 0.01 0.29 0.21 5.00
73 INT279107 Binding of COMP and MATN3 1 0.41 1.43 0.2 5.00
74 INT328310 DBT Positive_regulation of Localization of GH1 1 0.00 0 0.19 5.00
75 INT335020 Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.62 0.82 0.18 5.00
76 INT181996 TNFRSF11B Positive_regulation of Gene_expression of TIMP1 1 0.00 0.67 0.18 5.00
77 INT335018 Vdr Positive_regulation of Gene_expression of Fgf23 1 0.44 0.36 0.17 5.00
78 INT328379 Ghrl Positive_regulation of CRH 1 0.16 1.17 0.16 5.00
79 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
80 INT181997 TNFRSF11B Negative_regulation of CTSK 1 0.05 0.58 0.14 5.00
81 INT335026 Positive_regulation of Fgf23 Positive_regulation of Gene_expression of Cyp24a1 1 0.45 0.2 0.13 5.00
82 INT335024 Positive_regulation of Fgf23 Negative_regulation of Gene_expression of Cyp27b1 1 0.39 0.19 0.13 5.00
83 INT328384 Ghrl Positive_regulation of ALPL 1 0.01 0.93 0.13 5.00
84 INT212139 Slc4a3 Positive_regulation of Cl 1 0.07 0 0.12 5.00
85 INT212138 Slc4a3 Positive_regulation of Gene_expression of Cl 1 0.07 0 0.12 5.00
86 INT328313 Binding of CD36 and LDLR 1 0.00 0.63 0.11 5.00
87 INT328294 GHS Positive_regulation of Localization of GHRH 1 0.10 0.12 0.11 5.00
88 INT231223 Binding of KCNQ1 and Nav1 1 0.03 0.59 0.11 5.00
89 INT328370 Binding of CD36 and Fabp1 1 0.01 0.64 0.11 5.00
90 INT220149 Binding of IGF1 and IGFALS 2 0.39 0.44 0.1 5.00
91 INT328364 Binding of GHRH and Ghrl 1 0.09 0.2 0.1 5.00
92 INT328297 GHRH Positive_regulation of Transcription of GH1 1 0.04 0.26 0.1 5.00
93 INT328372 Ghrl Positive_regulation of Transcription of GH1 1 0.04 0.27 0.1 5.00
94 INT288219 Cigs1 Regulation of Nrgn 1 0.00 0.87 0.1 5.00
95 INT78446 Binding of GH1 and IGFBP3 1 0.11 0.48 0.1 5.00
96 INT279109 Binding of COL9A2 and MATN3 1 0.48 0.64 0.1 5.00
97 INT277890 Binding of Ids and Tas2r111-ps2 1 0.08 0.5 0.09 5.00
98 INT277889 Regulation of Binding of Ids and Tas2r111-ps2 1 0.09 0.5 0.09 5.00
99 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 5.00
100 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09 5.00
101 INT328373 Negative_regulation of Ghrl Positive_regulation of Localization of GH1 1 0.05 0.31 0.08 5.00
102 INT224985 Binding of Ube3a and Snord116 1 0.34 0.45 0.08 5.00
103 INT321867 TNFRSF11B Negative_regulation of TNFSF11 1 0.00 0.85 0.08 5.00
104 INT321868 Binding of TNFRSF11B and Negative_regulation of TNFSF11 1 0.00 0.91 0.08 5.00
105 INT328306 GH1 Positive_regulation of Localization of INS 1 0.01 0.12 0.07 5.00
106 INT328366 GPR39 Regulation of Localization of Ghrl 1 0.11 0.2 0.07 5.00
107 INT328380 AR Negative_regulation of Gene_expression of Ghrl 1 0.01 0.55 0.07 5.00
108 INT315987 Rhd Positive_regulation of Gene_expression of Igf1 1 0.10 0.47 0.07 5.00
109 INT78445 Binding of GHRH and IGF1 1 0.20 0.72 0.06 5.00
110 INT323043 Binding of CYP21A1P and HLA-DOA 1 0.04 1.48 0.06 5.00
111 INT323042 Binding of CYP21A2 and HLA-DOA 1 0.04 1.49 0.06 5.00
112 INT328305 GHS Positive_regulation of Localization of INS 1 0.02 0.07 0.05 5.00
113 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
114 INT335023 Fgf21 Positive_regulation of Gene_expression of Igf1 1 0.49 0.65 0.05 5.00
115 INT328387 INS Negative_regulation of Gene_expression of Ghrl 1 0.01 0.6 0.05 5.00
116 INT328371 Ghrl Negative_regulation of INS 1 0.03 0.13 0.05 5.00
117 INT328376 Ghrl Negative_regulation of SST 1 0.03 0.13 0.05 5.00
118 INT328383 Ghrl Negative_regulation of MBOAT4 1 0.26 0 0.05 5.00
119 INT328367 KISS1 Positive_regulation of Localization of Gnrh1 1 0.00 0 0.05 5.00
120 INT328308 CRH Negative_regulation of KISS1 1 0.02 0 0.05 5.00
121 INT328292 KISS1 Positive_regulation of Localization of PLOD1 1 0.00 0 0.05 5.00
122 INT328293 Binding of JAG2 and GHS 1 0.03 0.09 0.05 5.00
123 INT328365 Binding of JAG2 and Ghrl 1 0.03 0.07 0.05 5.00
124 INT315986 Igf1 Positive_regulation of Pik3c3 1 0.00 0.48 0.05 5.00
125 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
126 INT224988 Binding of Snord116 and Snurf 1 0.15 0.22 0.04 5.00
127 INT224991 Snord116 Positive_regulation of SNORD108 1 0.37 0.61 0.04 5.00
128 INT335017 Fgf23 Positive_regulation of Fgfr1 1 0.23 0.59 0.04 5.00
129 INT328363 Ghrl Negative_regulation of PLOD1 1 0.02 0.11 0.04 5.00
130 INT224986 Binding of Snrpn and Snord116 1 0.30 0.21 0.04 5.00
131 INT224990 Snord116 Positive_regulation of SNORD107 1 0.38 0.62 0.04 5.00
132 INT224987 Snord116 Positive_regulation of Snord64 1 0.55 0.62 0.04 5.00
133 INT328332 Ghrl Negative_regulation of Abo 1 0.01 0 0.04 5.00
134 INT264148 Binding of CLCN7 and Ostm1 1 0.17 0.72 0.03 5.00
135 INT335016 Fgf23 Negative_regulation of Gene_expression of Slc34a3 1 0.03 0.63 0.03 5.00
136 INT328362 LYPLA1 Regulation of Ghrl 1 0.04 0.07 0.03 5.00
137 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03 5.00
138 INT270776 PTH Regulation of Negative_regulation of DMD 1 0.09 0.3 0.03 5.00
139 INT328381 Ghrl Positive_regulation of NPY 1 0.06 0.15 0.03 5.00
140 INT307054 RHCE Regulation of AKTIP 1 0.00 0.6 0 5.00
141 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 5.00
142 INT315984 Rhd Positive_regulation of Localization of Igf1 1 0.07 0.25 0 5.00
143 INT279110 COMP Regulation of Localization of MATN3 1 0.59 0.45 0 5.00
144 INT335013 Fgf21 Positive_regulation of Localization of Ins1 1 0.06 0.58 0 5.00
145 INT328369 Ghrl Negative_regulation of CRH 1 0.16 0.15 0 5.00
146 INT278495 IGFBP2 Positive_regulation of Gene_expression of IGF1 1 0.20 0 0 5.00
147 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0 5.00
148 INT278498 IGFBP3 Regulation of GH1 1 0.06 0 0 5.00
149 INT264143 TCIRG1 Regulation of BSND 1 0.02 0.74 0 5.00
150 INT270780 BPs Positive_regulation of DMD 1 0.02 0 0 5.00
151 INT307306 Gene_expression of COMP Positive_regulation of CALR 1 0.27 0.99 0 5.00
152 INT307305 Gene_expression of COMP Positive_regulation of Positive_regulation of CALR 1 0.27 0.41 0 5.00
153 INT265964 TNNI2 Regulation of CA2 1 0.22 0.09 0 5.00
154 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0 5.00
155 INT279106 MATN3 Regulation of COMP 1 0.44 0.67 0 5.00
156 INT335012 Fgf21 Positive_regulation of Gene_expression of Ins1 1 0.06 0.57 0 5.00
157 INT279108 MATN3 Regulation of Localization of COMP 1 0.44 0.67 0 5.00
158 INT264144 CLCN7 Regulation of ADO 1 0.04 0.71 0 5.00
159 INT301365 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.38 0 5.00
160 INT227399 Binding of D5Mit424 and Alms1 1 0.01 0.71 0 5.00
161 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0 5.00
162 INT266835 Pth Regulation of Slc34a3 1 0.19 0.07 0 5.00
163 INT328375 Ghrl Negative_regulation of LEP 1 0.07 0.15 0 5.00
164 INT270778 Binding of TNFSF11 and CALCRL 1 0.00 0.44 0 5.00
165 INT255385 Binding of COL1A2 and DSPP 1 0.40 0.12 0 5.00
166 INT301364 Stat1 Positive_regulation of Cdkn1a 1 0.03 0.39 0 5.00
167 INT307307 COMP Positive_regulation of EREG 1 0.01 0.46 0 5.00
168 INT335022 Fgf15 Regulation of Pbx1 1 0.15 0.17 0 5.00
169 INT277891 Binding of TPBG and M6pr-ps 1 0.02 0.06 0 5.00
170 INT192618 Atrx Regulation of Gene_expression of Hba-a1 1 0.08 0.45 0 5.00
171 INT307309 Binding of CALR and EREG 1 0.00 0.83 0 5.00
172 INT266836 Pth Regulation of Slc34a1 1 0.09 0.07 0 5.00
173 INT184468 Negative_regulation of CRX Negative_regulation of Vwf 1 0.02 0.1 0 5.00
174 INT184461 Binding of Adamts1 and Furin 1 0.09 0 0 5.00
175 INT328368 Ghrl Positive_regulation of INS 1 0.04 0.22 0 5.00
176 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0 5.00
177 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0 5.00
178 INT301366 Fgf18 Positive_regulation of Fgfr3 1 0.04 0.34 0 5.00
179 INT335019 Fgf23 Positive_regulation of Phosphorylation of Mapk1 1 0.08 0.45 0 5.00
180 INT315985 Rhd Positive_regulation of Igf1 1 0.07 0.25 0 5.00
181 INT278494 IGFBP3 Positive_regulation of Binding of IGF1 and IGFBP3 1 0.17 0 0 5.00
182 INT266834 Pth Negative_regulation of Positive_regulation of Grxcr1 1 0.04 0.51 0 5.00
183 INT180836 Binding of CTD and NF1 1 0.15 0.2 0 5.00
184 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0 5.00
185 INT307310 Binding of CALR and COMP 1 0.28 0.82 0 5.00
186 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0 5.00
187 INT278499 IGFALS Regulation of GH1 1 0.18 0 0 5.00
188 INT227398 Binding of H2afy and Alms1 1 0.01 1.42 0 5.00
189 INT317900 Binding of NCAPH2 and MCPH1 1 0.02 0.53 0 5.00
190 INT307308 Binding of COMP and EREG 1 0.01 0.41 0 5.00
191 INT269769 Gh Regulation of Gene_expression of Igf1 1 0.04 0.98 0 5.00
192 INT210285 Ccrs1 Regulation of RAI1 1 0.00 0.37 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Growth Problems. They are ordered first by their pain relevance and then by number of times they were reported in Growth Problems. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT248 Positive_regulation of Localization of GH1 137 0.69 49.25 32.92 100.00
2 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 100.00
3 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 100.00
4 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 100.00
5 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 100.00
6 INT51953 Positive_regulation of Binding of Gnrhr 2 0.36 0.73 0.59 100.00
7 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 99.98
8 INT319565 Positive_regulation of Gene_expression of GHR 1 0.25 0.4 0 99.98
9 INT1893 Localization of Gh 1041 0.79 340.23 256.58 99.96
10 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 99.96
11 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 99.96
12 INT28300 Gene_expression of GHR 10 0.78 4.29 1.5 99.90
13 INT914 Positive_regulation of GH1 292 0.69 100.7 84.91 99.88
14 INT249 Localization of GHRH 215 0.80 78.02 51.87 99.88
15 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 99.88
16 INT250 Regulation of GHRH 65 0.61 17.46 23.19 99.88
17 INT158 Localization of Prl 2431 0.81 378.96 952.2 99.88
18 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 99.88
19 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 99.84
20 INT4378 Regulation of Gene_expression of GH1 26 0.47 10.2 4.61 99.84
21 INT252 Localization of GH1 529 0.80 227.4 122.05 99.82
22 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 99.80
23 INT1530 Regulation of Gh 382 0.61 115.96 112.47 99.78
24 INT3559 Negative_regulation of Localization of Gnrhr 73 0.58 18.89 26.41 99.78
25 INT211972 Regulation of Best1 18 0.33 12.04 0.67 99.72
26 INT17539 Positive_regulation of Igf1 68 0.69 28.47 13.02 99.68
27 INT985 Negative_regulation of GH1 213 0.57 89.53 32.39 99.62
28 INT952 Negative_regulation of GHRH 57 0.56 25.3 10.34 99.62
29 INT954 Positive_regulation of Gene_expression of GHRH 18 0.50 7.6 1.63 99.62
30 INT957 Positive_regulation of GHRH 136 0.70 36.84 40.52 99.62
31 INT16130 Binding of IGF1 67 0.48 27.43 2.95 99.60
32 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 99.56
33 INT144356 Gene_expression of GHS 4 0.57 10.76 2.21 99.50
34 INT246464 Positive_regulation of Gene_expression of GHS 2 0.27 4.68 0.51 99.50
35 INT3448 Positive_regulation of Gh 521 0.69 180.03 161.18 99.46
36 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 99.44
37 INT18660 Binding of Gnrhr 45 0.41 10.6 16.85 99.44
38 INT34741 Positive_regulation of Gene_expression of GH1 58 0.67 35.06 7.8 99.38
39 INT174106 Binding of Renbp 18 0.24 15.82 0.58 99.38
40 INT98805 Positive_regulation of Negative_regulation of GH1 2 0.36 1.43 0.06 99.36
41 INT255 Regulation of Localization of GH1 89 0.62 18.71 35.3 99.32
42 INT767 Localization of Gnrhr 565 0.80 106.68 214.57 99.28
43 INT27561 Negative_regulation of Negative_regulation of GH1 2 0.15 0.38 0.18 99.28
44 INT27562 Negative_regulation of Negative_regulation of GHRH 1 0.27 0.31 0.18 99.28
45 INT1309 Positive_regulation of Localization of Gnrhr 152 0.69 24.25 81.56 99.28
46 INT102377 Binding of GHS 4 0.22 2.62 0.7 99.28
47 INT246463 Negative_regulation of GHS 2 0.17 2.73 0.75 99.28
48 INT319564 Negative_regulation of Gene_expression of SHOX 1 0.35 3.66 0 99.26
49 INT9678 Positive_regulation of Positive_regulation of GH1 32 0.68 8.14 12.97 99.22
50 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.20
51 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 99.20
52 INT28861 Binding of Gh 61 0.46 25.61 6.38 99.16
53 INT97909 Binding of COMP 13 0.37 5.98 1.22 99.08
54 INT5127 Localization of Lhb 488 0.80 50.48 162.66 99.08
55 INT65070 Gene_expression of SHOX 9 0.55 7.72 1.84 99.02
56 INT36675 Negative_regulation of Pepd 3 0.47 8.99 0.63 98.80
57 INT125479 Positive_regulation of HHIP 38 0.44 12.39 3.75 98.76
58 INT955 Gene_expression of GHRH 126 0.78 59.91 20.74 98.50
59 INT193361 Positive_regulation of Gene_expression of SHOX 2 0.41 0.79 0 98.38
60 INT55982 Negative_regulation of Negative_regulation of Gh 4 0.55 1.02 0.88 98.36
61 INT4420 Positive_regulation of GOT1 103 0.64 88.4 18.38 98.32
62 INT163114 Positive_regulation of Gene_expression of GOT1 7 0.24 8.93 0.5 98.32
63 INT9683 Binding of GH1 57 0.47 21.14 5.99 98.30
64 INT28951 Negative_regulation of IGF1 133 0.59 75.77 18.9 98.20
65 INT82829 Gene_expression of COMP 104 0.78 57 9.81 98.16
66 INT209334 Regulation of Filipino 1 0.09 1.4 0.29 98.16
67 INT4419 Gene_expression of GOT1 20 0.65 22.53 2.53 98.14
68 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78 98.12
69 INT117855 Negative_regulation of Ghrl 29 0.57 17.52 5 98.08
70 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07 97.92
71 INT68260 Localization of BGLAP 34 0.78 16.04 4.63 97.92
72 INT205619 Regulation of Renbp 6 0.17 1.91 0.55 97.84
73 INT278718 Gene_expression of STAT5B 2 0.43 1.55 0.34 97.56
74 INT19008 Positive_regulation of Positive_regulation of Ghrh 15 0.49 2.4 4.55 97.40
75 INT82828 Positive_regulation of COMP 45 0.61 35.12 6.2 97.36
76 INT184436 Regulation of Gene_expression of Adamts1 6 0.60 9.53 0.62 97.28
77 INT738 Regulation of POMC 459 0.62 111.19 243.74 97.20
78 INT205618 Gene_expression of Renbp 15 0.26 9.26 1.04 97.12
79 INT28949 Negative_regulation of Positive_regulation of IGF1 11 0.42 5.03 1.11 96.96
80 INT75111 Negative_regulation of Positive_regulation of IGFBP3 2 0.40 3.44 0.09 96.96
81 INT5100 Positive_regulation of Ghrh 100 0.64 24.2 30.21 96.92
82 INT13454 Positive_regulation of Positive_regulation of Gh 49 0.68 14.53 18.49 96.92
83 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 96.88
84 INT131456 Negative_regulation of MMRN1 14 0.19 9.49 2.29 96.88
85 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 96.84
86 INT48728 Negative_regulation of IGFBP3 28 0.59 14.84 1.21 96.76
87 INT133889 Gene_expression of Adamts1 78 0.76 48.05 6.58 96.72
88 INT53562 Negative_regulation of CSF2RA 3 0.56 0.76 0.04 96.72
89 INT67341 Transcription of IGFBP3 27 0.72 30.46 0.57 96.68
90 INT148 Positive_regulation of Gnrhr 182 0.70 47.44 79.64 96.64
91 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 96.60
92 INT48725 Gene_expression of IGFBP3 128 0.78 78.83 8.19 96.52
93 INT326 Gene_expression of Gnrhr 105 0.76 35.87 34.93 96.52
94 INT19900 Binding of GHRH 22 0.37 5.75 5 96.52
95 INT124720 Regulation of Gene_expression of IGFBP3 2 0.39 3.1 0.26 96.52
96 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 96.52
97 INT34777 Localization of IGF1 82 0.80 42.68 8.62 96.48
98 INT211968 Localization of Best1 11 0.40 9.33 0.38 96.48
99 INT3217 Regulation of Ins1 154 0.62 87.11 27.29 96.34
100 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 96.24
101 INT66709 Transcription of IGF1 13 0.71 5.65 1.64 96.20
102 INT16303 Negative_regulation of Localization of GH1 89 0.59 37.31 22.15 96.08
103 INT10841 Positive_regulation of Gene_expression of Gh 101 0.59 45.39 16.96 96.00
104 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 95.92
105 INT31073 Regulation of Negative_regulation of GNRH1 2 0.27 1.55 0.62 95.92
106 INT118097 Localization of COMP 18 0.70 9.99 1.42 95.88
107 INT279130 Negative_regulation of Localization of COMP 5 0.51 3.75 0.69 95.88
108 INT72129 Positive_regulation of Positive_regulation of IGF1 11 0.50 4.61 1.05 95.68
109 INT51279 Regulation of IGFBP3 17 0.49 15.89 2.45 95.56
110 INT49370 Localization of IGFBP3 21 0.81 9.85 0.71 95.56
111 INT124721 Regulation of Localization of IGFBP3 1 0.10 0.23 0.07 95.56
112 INT16186 Negative_regulation of HADH 2 0.42 1.17 0.91 95.52
113 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 95.36
114 INT173578 Negative_regulation of CTSK 8 0.44 6.29 1.15 95.20
115 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 94.80
116 INT118095 Regulation of COMP 7 0.43 9.69 3.33 94.76
117 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 94.48
118 INT135879 Localization of MATN3 12 0.80 10.31 1.44 94.36
119 INT49362 Positive_regulation of Localization of Igf1 4 0.65 2.26 0.53 94.28
120 INT5128 Positive_regulation of Lhb 232 0.69 44.23 71.26 94.24
121 INT5126 Positive_regulation of Positive_regulation of Lhb 16 0.48 2.12 5.23 94.24
122 INT7224 Positive_regulation of Gene_expression of Lhb 18 0.45 10.22 3.4 94.24
123 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 94.04
124 INT49360 Localization of Igf1 22 0.76 6.96 4.26 93.88
125 INT987 Localization of TRH 37 0.78 10.53 11.1 93.84
126 INT921 Regulation of GH1 172 0.60 52.88 51.04 93.28
127 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 93.00
128 INT313892 Localization of CADPS 1 0.48 2.37 0.2 92.84
129 INT16530 Gene_expression of Ghrh 45 0.77 6.22 13.44 92.52
130 INT23367 Positive_regulation of Positive_regulation of Gnrh1 9 0.50 0.97 2.97 92.40
131 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 92.32
132 INT19 Regulation of Gnrhr 131 0.62 36.4 55.66 92.32
133 INT2123 Positive_regulation of Gnrh1 209 0.70 24.2 68.97 91.92
134 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 91.64
135 INT986 Negative_regulation of Localization of GHRH 16 0.58 8.57 3.16 91.48
136 INT397 Localization of SST 232 0.81 58.05 101.19 91.28
137 INT245751 Gene_expression of COL9A2 4 0.65 1.83 0.04 91.12
138 INT307323 Negative_regulation of Gene_expression of COL9A2 1 0.06 0.74 0.04 91.12
139 INT251 Regulation of INS 398 0.62 232.47 55.04 91.08
140 INT143833 Positive_regulation of Foxc1 2 0.42 1.02 0.09 91.04
141 INT143832 Positive_regulation of Barx1 1 0.19 0.86 0.09 91.04
142 INT143834 Positive_regulation of Pitx2 1 0.22 0.86 0.09 91.04
143 INT984 Positive_regulation of Localization of GHRH 58 0.70 12.66 16.51 90.72
144 INT443 Localization of POMC 1020 0.81 284.52 443.17 90.32
145 INT5453 Regulation of Localization of POMC 114 0.62 20.56 56.34 90.32
146 INT118371 Positive_regulation of Fgf23 15 0.69 25.34 0.85 89.76
147 INT118373 Gene_expression of Fgf23 16 0.77 29.62 1.04 89.76
148 INT135880 Positive_regulation of Gene_expression of Fgf23 4 0.46 7.52 0.29 89.76
149 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 89.68
150 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 89.24
151 INT224948 Negative_regulation of Pdia6 3 0.15 2.54 1.67 89.24
152 INT254 Regulation of Localization of GHRH 30 0.60 5.17 11.46 89.16
153 INT143835 Gene_expression of Foxc1 2 0.39 1.17 0.09 88.96
154 INT143836 Negative_regulation of Foxc1 1 0.35 0.92 0.09 88.96
155 INT211969 Positive_regulation of Best1 34 0.11 14.92 1.44 88.88
156 INT143830 Gene_expression of Barx1 1 0.23 0.91 0.09 88.52
157 INT143831 Negative_regulation of Barx1 1 0.16 0.91 0.09 88.52
158 INT197143 Positive_regulation of Renbp 15 0.33 9.41 1.31 88.48
159 INT334975 Gene_expression of Fgf15 1 0.74 7.12 2.02 88.40
160 INT72703 Gene_expression of Ide 79 0.70 45.04 4.47 88.36
161 INT7414 Regulation of Localization of SST 31 0.60 4.85 17.46 88.24
162 INT143837 Negative_regulation of Pitx2 1 0.19 0.91 0.09 88.24
163 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 88.24
164 INT76860 Gene_expression of HSPG2 32 0.65 37.14 9.06 88.12
165 INT4360 Gene_expression of Hypism 29 0.22 38.1 4.07 88.04
166 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 88.00
167 INT205617 Negative_regulation of Positive_regulation of Renbp 1 0.16 1.04 0.21 87.80
168 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95 87.72
169 INT10843 Regulation of Regulation of Gh 14 0.22 5.56 5.93 87.60
170 INT693 Negative_regulation of Localization of SST 46 0.59 8.57 21.75 87.52
171 INT185240 Binding of Fgf2 14 0.37 7.39 0.59 87.52
172 INT425 Localization of PRL 455 0.81 189.64 144.8 87.48
173 INT165954 Gene_expression of SLC12A1 3 0.55 1.32 0.1 87.16
174 INT3161 Regulation of Localization of Gh 163 0.61 35.43 59.45 87.04
175 INT119540 Binding of Nfe2l2 29 0.48 6.34 1.74 87.04
176 INT25070 Negative_regulation of Ndufs2 3 0.21 0.99 1.13 86.92
177 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 86.88
178 INT55047 Gene_expression of GNRHR 8 0.78 5.2 0.53 86.60
179 INT256399 Positive_regulation of ND4 1 0.01 1.36 0 86.48
180 INT36777 Gene_expression of CTD 12 0.41 11.47 1.42 85.96
181 INT78938 Binding of IGFBP3 40 0.45 27.95 1.73 85.88
182 INT124211 Protein_catabolism of IGF1 2 1.00 1.29 0.63 85.64
183 INT15982 Positive_regulation of NLRP3 25 0.65 23.19 3.57 85.32
184 INT7113 Negative_regulation of Localization of CGA 71 0.51 17.7 23.42 85.12
185 INT152395 Binding of SLC34A3 1 0.09 1.27 0.08 84.96
186 INT179300 Negative_regulation of TGFB1I1 1 0.06 1.92 0 84.84
187 INT63364 Positive_regulation of Igfbp3 9 0.64 1.92 0.53 84.64
188 INT142344 Transcription of Igf1 22 0.69 7.55 6.77 84.40
189 INT23764 Regulation of Localization of TRH 4 0.45 0.75 1.4 84.32
190 INT29898 Negative_regulation of C6orf25 16 0.29 9.58 1.33 84.20
191 INT210272 Binding of Ccrs1 1 0.01 1.13 0 84.12
192 INT5454 Localization of CRH 124 0.79 79.18 41.53 83.92
193 INT23763 Regulation of Localization of CRH 6 0.48 0.22 3.04 83.92
194 INT202702 Binding of IGF2BP3 2 0.36 3.82 0.08 83.88
195 INT14572 Binding of INS 205 0.48 175.43 13.38 83.88
196 INT59899 Regulation of MATN3 4 0.45 7.61 1.6 83.84
197 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 83.84
198 INT1577 Negative_regulation of Gene_expression of PRL 24 0.59 7.7 3.15 83.84
199 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 83.56
200 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 83.56
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