D:Hematemesis

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pChart

Disease Term
Synonyms Hematemeses
Documents 370
Hot Single Events 33
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hematemesis. They are ordered first by their relevance to Hematemesis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT287380 Binding of VEGFA and Kdr 12 0.18 11.97 0.34 5.00
2 INT292621 Binding of IL6 and Gpt 1 0.01 3.88 0.24 5.00
3 INT292615 Binding of IL6 and SLC17A5 1 0.01 1.8 0.16 5.00
4 INT275231 Binding of ACVRL1 and AK3 1 0.01 0.72 0 5.00
5 INT353125 Negative_regulation of Binding of VEGFA and Kdr 1 0.04 5.92 0 5.00
6 INT318806 Binding of VEGFA and NCOA1 1 0.00 0.22 0 5.00
7 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hematemesis. They are ordered first by their pain relevance and then by number of times they were reported in Hematemesis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 96.24
2 INT22024 Negative_regulation of HBG1 45 0.58 26 6.8 95.72
3 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 92.12
4 INT36556 Gene_expression of GGT2 6 0.21 3.75 0.76 92.12
5 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 90.56
6 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 89.92
7 INT159531 Positive_regulation of Gene_expression of SLC17A5 8 0.49 9.3 0.77 89.92
8 INT199004 Gene_expression of ARMC9 43 0.58 17.72 1.32 89.40
9 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 88.96
10 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 88.80
11 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 88.64
12 INT326328 Positive_regulation of Positive_regulation of ARMC9 1 0.02 0.63 0 87.96
13 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 87.60
14 INT197721 Positive_regulation of ARMC9 36 0.35 20.08 1.03 87.52
15 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 86.76
16 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 86.60
17 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 86.60
18 INT27591 Negative_regulation of Gene_expression of Alb 30 0.58 17.03 5.99 86.60
19 INT76217 Gene_expression of Spdef 13 0.62 4.86 2.32 86.24
20 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 85.92
21 INT26996 Positive_regulation of Gene_expression of Crp 21 0.68 21.55 2.75 85.92
22 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 85.52
23 INT58060 Negative_regulation of HMI 30 0.44 11.9 5.06 85.16
24 INT504 Gene_expression of GPT 42 0.75 27.54 3.99 84.76
25 INT717 Regulation of F2 29 0.61 17.46 6.99 84.24
26 INT17489 Regulation of F13A1 28 0.45 15.79 4.93 84.24
27 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 83.76
28 INT36702 Gene_expression of CEACAM3 4 0.68 4.56 0.58 83.16
29 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 83.00
30 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 82.80
31 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 82.80
32 INT8775 Binding of IGHE 167 0.48 102.61 23.54 81.44
33 INT1888 Protein_catabolism of F13A1 97 0.99 63.48 14.82 80.72
34 INT10146 Negative_regulation of Vwf 27 0.40 17.11 3.69 78.52
35 INT176618 Gene_expression of HEY1 29 0.59 36 4.37 77.36
36 INT8683 Positive_regulation of F3 31 0.67 42.89 6.21 76.80
37 INT124944 Regulation of KIT 15 0.60 11.84 0.24 75.60
38 INT9899 Gene_expression of Vwf 91 0.74 45.06 9.13 74.80
39 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 72.20
40 INT3881 Positive_regulation of Protein_catabolism of F13A1 21 0.41 20 3.28 71.84
41 INT8792 Gene_expression of GBA 20 0.78 14.73 1.98 71.84
42 INT148721 Binding of PSMD1 13 0.31 4.78 1.76 71.60
43 INT11689 Binding of PSMD2 16 0.36 2.77 0.34 71.60
44 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 70.88
45 INT3808 Positive_regulation of Gif 3 0.41 2.51 0.75 70.84
46 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 67.52
47 INT105021 Binding of GOPC 187 0.40 60.39 20.38 59.88
48 INT12237 Positive_regulation of Lipg 19 0.60 11.09 2.92 53.92
49 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 53.68
50 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 52.48
51 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 51.36
52 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 47.00
53 INT11238 Positive_regulation of ADA 33 0.70 39.7 9.98 43.16
54 INT192073 Positive_regulation of Gene_expression of ADA 8 0.47 10.35 1.12 43.16
55 INT310904 Transcription of GIT1 1 0.05 0.8 0.58 43.04
56 INT68202 Gene_expression of ADA 26 0.68 23.15 5.18 42.24
57 INT154057 Gene_expression of Ear1 14 0.41 9.72 1.12 34.00
58 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 26.28
59 INT202591 Regulation of AVL9 2 0.02 1.58 0.19 25.68
60 INT625 Localization of PGC 35 0.80 11.33 3.05 22.00
61 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 21.32
62 INT114412 Localization of HCL1 18 0.56 3.69 2.96 21.12
63 INT166227 Negative_regulation of Localization of HCL1 2 0.05 1.26 1.03 21.12
64 INT295943 Negative_regulation of MTNR1A 4 0.21 2.66 0.24 19.52
65 INT310903 Positive_regulation of GIT1 1 0.04 0.57 0.7 18.52
66 INT9210 Regulation of IL6 166 0.62 125.61 49.95 14.00
67 INT10835 Regulation of IL8 79 0.49 53.04 24.14 14.00
68 INT15796 Regulation of IL2 66 0.61 25.43 20.62 14.00
69 INT73497 Regulation of IL10 33 0.45 22.6 9.19 14.00
70 INT171562 Regulation of IL4 19 0.36 12.12 5.33 14.00
71 INT110569 Gene_expression of XDH 31 0.75 18.35 1.34 13.32
72 INT24019 Negative_regulation of HPS1 7 0.37 7.94 1.04 11.88
73 INT12339 Localization of IL8 437 0.81 251.87 117.39 11.68
74 INT12082 Localization of IL6 365 0.81 241.78 105.78 11.68
75 INT10763 Localization of IL2 157 0.80 81.11 33.21 11.68
76 INT74423 Localization of IL10 91 0.80 61.6 22.95 11.68
77 INT69158 Localization of IL4 48 0.71 31.3 11.98 11.68
78 INT15610 Localization of GOPC 223 0.65 68.26 28.7 11.60
79 INT6623 Gene_expression of NA 231 0.78 45.78 59.36 10.64
80 INT3892 Positive_regulation of XDH 8 0.67 8.57 1.5 8.80
81 INT49993 Positive_regulation of Gene_expression of Il6 149 0.70 88.07 53.78 8.60
82 INT71374 Positive_regulation of Gene_expression of Il12a 5 0.22 7.49 3.8 8.60
83 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 8.32
84 INT67401 Gene_expression of Il12a 25 0.55 20.04 11.12 7.96
85 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 7.60
86 INT9191 Localization of EDN1 94 0.81 57.01 14.78 7.08
87 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 6.16
88 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
89 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 5.00
90 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
91 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 5.00
92 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
93 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
94 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
95 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
96 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
97 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
98 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 5.00
99 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
100 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 5.00
101 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 5.00
102 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
103 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
104 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 5.00
105 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
106 INT48244 Gene_expression of Il4 172 0.76 132.38 73.42 5.00
107 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 5.00
108 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 5.00
109 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
110 INT39153 Positive_regulation of PTGS2 182 0.70 96.16 60.6 5.00
111 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 5.00
112 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
113 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
114 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 5.00
115 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 5.00
116 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
117 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
118 INT77652 Negative_regulation of Gene_expression of IL8 99 0.59 67.57 30.21 5.00
119 INT9993 Positive_regulation of Gene_expression of IL2 131 0.69 46.27 30.04 5.00
120 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 5.00
121 INT70048 Positive_regulation of Gene_expression of IL10 90 0.55 71.34 25.66 5.00
122 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
123 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
124 INT8075 Localization of Crh 64 0.81 25.41 19.45 5.00
125 INT712 Positive_regulation of LDHA 160 0.70 175.25 19.11 5.00
126 INT192409 Positive_regulation of Gene_expression of IFN1@ 102 0.67 64.66 18.8 5.00
127 INT68681 Transcription of VEGFA 132 0.71 80.47 17.03 5.00
128 INT2243 Localization of GAST 67 0.81 34.54 16.19 5.00
129 INT24670 Gene_expression of FGF2 121 0.78 85.64 15.12 5.00
130 INT180497 Binding of MRI1 45 0.42 28.35 14.77 5.00
131 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66 5.00
132 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 5.00
133 INT59870 Gene_expression of F3 51 0.65 51.83 14.01 5.00
134 INT39733 Localization of NFKB1 59 0.79 22.76 13.99 5.00
135 INT86383 Negative_regulation of EGFR 258 0.59 173.94 13.32 5.00
136 INT13823 Gene_expression of Egf 97 0.78 39.99 12.99 5.00
137 INT24816 Binding of CD40LG 68 0.47 45.48 11.56 5.00
138 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 5.00
139 INT6574 Negative_regulation of Pla2g1b 35 0.59 11.4 10.44 5.00
140 INT2378 Negative_regulation of SERPINE1 47 0.59 34.55 9.9 5.00
141 INT170333 Binding of IFN1@ 68 0.47 49.01 9.72 5.00
142 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
143 INT14301 Binding of CSF2 82 0.48 67.95 8.98 5.00
144 INT49802 Localization of MUC1 75 0.81 44.74 8.87 5.00
145 INT2093 Gene_expression of GAST 50 0.78 32.32 7.98 5.00
146 INT165036 Gene_expression of S100a9 38 0.77 38.33 7.84 5.00
147 INT8684 Positive_regulation of ANGPTL5 45 0.69 36.29 7.47 5.00
148 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 5.00
149 INT1124 Negative_regulation of CD40LG 53 0.57 36.26 7 5.00
150 INT95117 Gene_expression of PDGFA 71 0.71 51.17 6.9 5.00
151 INT83451 Positive_regulation of Gene_expression of CD40LG 26 0.60 22.81 6.25 5.00
152 INT30206 Negative_regulation of ADA 17 0.59 10.03 5.63 5.00
153 INT11360 Localization of SERPINE1 41 0.80 33.98 5.61 5.00
154 INT64888 Negative_regulation of HBM 52 0.16 34.33 5.45 5.00
155 INT21747 Localization of crf 8 0.47 5.32 5.06 5.00
156 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 5.00
157 INT28703 Negative_regulation of TFPI 29 0.38 19.81 4.93 5.00
158 INT624 Positive_regulation of GAST 28 0.70 15.61 4.73 5.00
159 INT14470 Gene_expression of HCC 83 0.67 110.55 4.61 5.00
160 INT8773 Gene_expression of HBG1 58 0.76 37.6 4.59 5.00
161 INT187286 Binding of HEY1 17 0.32 31.21 4.52 5.00
162 INT162249 Gene_expression of Hist1h2aa 8 0.12 6.46 4.35 5.00
163 INT63113 Positive_regulation of HRAS 30 0.67 22.85 4.28 5.00
164 INT10923 Positive_regulation of Lipg 30 0.50 22.87 4.26 5.00
165 INT69781 Negative_regulation of FGF2 22 0.42 17.25 4.24 5.00
166 INT103153 Positive_regulation of Transcription of VEGFA 34 0.69 22.16 4.22 5.00
167 INT5148 Regulation of CD40LG 25 0.44 21.58 4.05 5.00
168 INT134590 Localization of ADA 7 0.65 8.43 3.96 5.00
169 INT18515 Gene_expression of Lipg 18 0.66 9.3 3.72 5.00
170 INT62386 Negative_regulation of Gene_expression of IGHG3 12 0.20 7.94 3.62 5.00
171 INT38303 Binding of Gpt 21 0.47 15.84 3.43 5.00
172 INT150395 Binding of MEFV 55 0.44 31.18 3.42 5.00
173 INT119421 Negative_regulation of RAF1 10 0.41 6.94 3.31 5.00
174 INT6578 Regulation of Pla2g1b 11 0.49 3.94 3.19 5.00
175 INT17562 Negative_regulation of Lipg 32 0.51 16.91 3.17 5.00
176 INT104902 Regulation of ASIC1 6 0.51 5.17 3.13 5.00
177 INT120562 Negative_regulation of Egfr 108 0.59 79.38 3.11 5.00
178 INT54740 Positive_regulation of Localization of Crh 10 0.47 7.27 3.01 5.00
179 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88 5.00
180 INT597 Positive_regulation of PON1 26 0.62 19.14 2.87 5.00
181 INT15540 Positive_regulation of PDGFA 24 0.47 19.01 2.5 5.00
182 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 5.00
183 INT122656 Gene_expression of MTNR1A 21 0.75 6.37 2.46 5.00
184 INT70242 Localization of HCC 18 0.66 23.95 2.35 5.00
185 INT1153 Negative_regulation of FUT3 17 0.38 8.61 2.21 5.00
186 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 5.00
187 INT14 Regulation of LDHA 22 0.57 15.26 2.14 5.00
188 INT628 Negative_regulation of GAST 10 0.58 4.44 2.08 5.00
189 INT162247 Positive_regulation of Hist1h2aa 2 0.09 2.6 2.03 5.00
190 INT118291 Binding of TXK 19 0.10 11.77 1.94 5.00
191 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 5.00
192 INT79140 Binding of HCC 36 0.31 46.96 1.87 5.00
193 INT136503 Negative_regulation of KDR 46 0.48 43.1 1.86 5.00
194 INT140906 Negative_regulation of Gene_expression of Il12a 4 0.38 5.28 1.86 5.00
195 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 5.00
196 INT94189 Positive_regulation of FUT3 11 0.31 6.61 1.5 5.00
197 INT51635 Negative_regulation of LRTOMT 5 0.41 1.17 1.49 5.00
198 INT21744 Positive_regulation of Localization of crf 3 0.12 3.47 1.48 5.00
199 INT152223 Binding of BEST1 10 0.29 6.67 1.46 5.00
200 INT83891 Gene_expression of FUT3 20 0.61 10.49 1.41 5.00
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