D:Hemiplegia

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Disease Term
Synonyms CROSSED HEMIPLEGIA, Crossed Hemiplegias, Flaccid Hemiplegia, Flaccid Hemiplegias, HEMIPLEGIA CROSSED, Hemiplegia Flaccid, Hemiplegia Infantile, HEMIPLEGIA POST ICTAL, Hemiplegia Spastic, Hemiplegia Transient, HEMIPLEGIAS
Documents 640
Hot Single Events 46
Hot Interactions 2

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Hemiplegia. They are ordered first by their relevance to Hemiplegia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT189958 Binding of FND and SENP8 1 0.05 1.27 0 95.68
2 INT74840 Binding of Cacna1a and Cacna1a 5 0.00 4.24 2.36 84.76
3 INT140347 Binding of ATP1A2 and Cacna1a 1 0.11 2.88 2.73 73.12
4 INT181455 Binding of Ccr5 and Ccl5 11 0.39 12.13 3.66 5.00
5 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 5.00
6 INT189490 Binding of Ccr3 and Ccl5 1 0.33 8.54 2.6 5.00
7 INT202967 MCRS1 Negative_regulation of CPP 2 0.14 2.2 0.73 5.00
8 INT189493 Tnf Positive_regulation of Localization of Darc 1 0.00 0.53 0.37 5.00
9 INT189491 Icam1 Positive_regulation of Transcription of Ccl5 1 0.19 0.64 0.36 5.00
10 INT189492 Ifng Positive_regulation of Localization of Darc 1 0.00 0.53 0.34 5.00
11 INT189489 Il1b Positive_regulation of Localization of Darc 1 0.00 0.53 0.34 5.00
12 INT189494 Negative_regulation of Ccr5 Negative_regulation of Gene_expression of Hand1 1 0.16 0.66 0.32 5.00
13 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
14 INT279266 CADPS Positive_regulation of Regulation of IL1B 1 0.22 1.43 0.28 5.00
15 INT230775 CEBPZ Regulation of CPP 1 0.11 0.69 0.27 5.00
16 INT228611 Binding of DNMT3B and LEP 1 0.04 0 0.25 5.00
17 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 5.00
18 INT257844 STS Positive_regulation of Negative_regulation of CST7 1 0.01 0.24 0.19 5.00
19 INT279267 Binding of RIPK2 and Positive_regulation of Gene_expression of CASP1 1 0.26 1.12 0.14 5.00
20 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11 5.00
21 INT228610 Binding of DNMT3B and ASPRV1 1 0.02 0 0.05 5.00
22 INT217402 Binding of Bace1 and PSENEN 1 0.02 0.72 0 5.00
23 INT217399 Binding of Bace1 and Ncstn 1 0.05 0.72 0 5.00
24 INT249666 Binding of CD81 and GOPC 1 0.06 1.31 0 5.00
25 INT279268 CARD8 Positive_regulation of CASP1 1 0.32 0.3 0 5.00
26 INT217398 Binding of Psen2 and Bace1 1 0.12 1.44 0 5.00
27 INT249664 Binding of CD81 and CHCHD2 1 0.00 2.51 0 5.00
28 INT217400 Binding of Psen1 and Bace1 1 0.17 1.43 0 5.00
29 INT217396 Binding of Abca1 and App 1 0.26 0.83 0 5.00
30 INT187850 Binding of PMP2 and PRM1 1 0.04 1.21 0 5.00
31 INT217397 Binding of Bace1 and Alph1 1 0.02 0.73 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Hemiplegia. They are ordered first by their pain relevance and then by number of times they were reported in Hemiplegia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT30101 Regulation of Cacna1a 25 0.45 14.38 12.43 99.92
2 INT80450 Positive_regulation of SPR 3 0.41 0.9 0.93 99.38
3 INT224413 Positive_regulation of CIMT 25 0.68 23.61 3.14 99.24
4 INT108728 Regulation of ATP1A2 4 0.45 3.65 3.04 98.92
5 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 98.76
6 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 98.76
7 INT26698 Positive_regulation of Cacna1a 37 0.67 26.33 39.1 98.64
8 INT2072 Localization of AMBP 33 0.65 37.58 4.84 98.32
9 INT21869 Negative_regulation of Otc 16 0.58 8.43 3.67 98.04
10 INT116001 Binding of FND 3 0.06 3.69 0.1 98.00
11 INT156061 Regulation of MGR 1 0.11 0.64 0.54 97.76
12 INT107905 Gene_expression of BCL2L11 9 0.75 7.58 1.92 97.68
13 INT31136 Binding of Cacna1a 28 0.45 30.76 17.35 97.64
14 INT12111 Negative_regulation of Hbb-ar 11 0.37 6.63 4.22 96.56
15 INT187851 Gene_expression of Hbb-ar 40 0.65 16.34 2.3 96.56
16 INT224414 Regulation of CIMT 15 0.39 11.75 1.42 96.48
17 INT62869 Negative_regulation of REG3A 4 0.57 4.31 0.82 94.68
18 INT82918 Binding of AMBP 23 0.39 23.31 1.71 94.52
19 INT48882 Binding of GRIN3B 9 0.46 5.12 7.66 94.36
20 INT123978 Binding of GRIA1 3 0.41 3.5 2.62 94.36
21 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 93.40
22 INT157332 Localization of Ea2 1 0.07 0.71 0.32 92.92
23 INT16396 Negative_regulation of CEBPZ 76 0.48 30.03 21.6 92.80
24 INT96542 Negative_regulation of SMN1 14 0.51 10.72 3.11 92.80
25 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 92.76
26 INT72924 Negative_regulation of MCRS1 27 0.19 33.59 10.29 92.56
27 INT79556 Gene_expression of GRIN3B 16 0.77 7.71 10.75 92.24
28 INT48784 Gene_expression of GRIA1 12 0.78 3.25 4.11 92.24
29 INT66331 Gene_expression of Cacna1a 101 0.78 49.58 46.32 91.56
30 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65 91.40
31 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54 91.40
32 INT129312 Gene_expression of SGCB 24 0.76 18.25 3.75 91.40
33 INT103553 Positive_regulation of Positive_regulation of MTX1 1 0.01 0.53 0.69 91.24
34 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 91.20
35 INT95226 Gene_expression of AHSA1 5 0.49 3.62 1.52 91.00
36 INT186271 Binding of Hbb-ar 3 0.47 2.66 0.79 90.64
37 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 90.56
38 INT103554 Positive_regulation of MTX1 19 0.45 11.23 10 90.28
39 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37 89.32
40 INT287526 Negative_regulation of Gene_expression of CACNA1A 1 0.42 4.25 3.81 89.20
41 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68 88.96
42 INT62870 Binding of ZNRF1 3 0.14 2.68 0.98 88.80
43 INT1376 Binding of Trh 121 0.48 20 69.86 85.56
44 INT16920 Positive_regulation of NR0B1 6 0.43 3.51 0.76 85.16
45 INT287525 Localization of CAV2 5 0.47 5.32 2 82.04
46 INT186507 Localization of ATP1A2 2 0.74 3.35 3.04 80.08
47 INT204019 Negative_regulation of C2 10 0.26 6.23 2.44 77.56
48 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 77.12
49 INT55733 Negative_regulation of VTN 47 0.58 47.22 5.68 76.88
50 INT149761 Negative_regulation of MAS1 5 0.29 1.91 1.95 76.68
51 INT3824 Negative_regulation of PTH 40 0.59 28.58 3.39 75.20
52 INT189960 Gene_expression of SENP8 9 0.54 17.54 0.64 73.84
53 INT162783 Binding of LIFR 1 0.36 1.52 0.86 72.32
54 INT156294 Binding of Hm 2 0.07 1.7 0.86 72.32
55 INT6133 Negative_regulation of Serpinc1 56 0.58 42.8 8.35 69.48
56 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 68.24
57 INT59961 Localization of Furin 3 0.76 2.21 0.2 66.72
58 INT184895 Gene_expression of MCRS1 46 0.42 56.03 19.44 65.76
59 INT181356 Positive_regulation of Gene_expression of Ccr5 11 0.66 8.3 2.24 64.16
60 INT143258 Positive_regulation of Gene_expression of Ccr3 4 0.49 3.16 1.27 64.16
61 INT63164 Negative_regulation of Cst7 51 0.50 18.48 20.3 64.08
62 INT167679 Gene_expression of Ccr5 74 0.75 59.03 18.16 63.68
63 INT89294 Gene_expression of Ccr3 53 0.68 43.9 12.62 63.68
64 INT166700 Localization of RNH1 2 0.73 3.33 0.73 62.96
65 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 61.60
66 INT2271 Gene_expression of F2 51 0.76 30.21 7.97 61.32
67 INT184890 Regulation of MCRS1 35 0.22 44.35 13.78 59.84
68 INT168409 Positive_regulation of Ccl5 47 0.64 45.84 10.83 59.16
69 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 58.68
70 INT189477 Positive_regulation of Ccr3 1 0.49 4.8 0.72 58.16
71 INT1190 Positive_regulation of F2 53 0.70 46.41 11.64 58.12
72 INT149762 Regulation of MAS1 8 0.31 5.34 1.61 57.96
73 INT153268 Positive_regulation of Ccr5 25 0.66 19 7.02 57.80
74 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 57.36
75 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 57.20
76 INT53574 Regulation of Tnf 45 0.62 40.68 19.71 56.92
77 INT79693 Regulation of Il4 30 0.51 21.96 8.6 56.92
78 INT102351 Regulation of Pecam1 7 0.61 22.45 7.58 56.92
79 INT56445 Regulation of Icam1 14 0.39 15.4 5.32 56.92
80 INT106189 Regulation of Il12a 18 0.44 12.4 5.3 56.92
81 INT181363 Regulation of Ccl5 16 0.46 13.65 5.09 56.92
82 INT112970 Regulation of Ccr1 8 0.29 7.77 1.93 56.92
83 INT99003 Regulation of Vcam1 7 0.41 6.91 1.04 56.92
84 INT181364 Regulation of Ccr5 3 0.32 1.81 0.62 56.92
85 INT189484 Regulation of Ccr3 1 0.19 1.07 0.23 56.92
86 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 56.32
87 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 56.32
88 INT60691 Gene_expression of Il12a 331 0.78 208.03 75.96 56.32
89 INT62543 Gene_expression of Icam1 231 0.78 187.58 52.71 56.32
90 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 56.32
91 INT85964 Gene_expression of Pecam1 109 0.78 69.73 15.21 56.32
92 INT16452 Negative_regulation of SERPIND1 13 0.59 8.43 1.83 53.96
93 INT34864 Binding of Cp 23 0.47 5.17 1.78 52.88
94 INT2512 Negative_regulation of Cp 27 0.51 10.15 8.37 52.48
95 INT256411 Phosphorylation of AMBP 1 0.08 10.3 0.73 52.04
96 INT142423 Negative_regulation of Positive_regulation of FLNA 2 0.05 0.99 0.89 51.36
97 INT241211 Negative_regulation of CIMT 8 0.37 2.67 0 51.36
98 INT181348 Localization of Ccl5 24 0.65 19.55 6.8 51.12
99 INT209501 Gene_expression of CADPS 15 0.65 20.7 2.22 50.00
100 INT63880 Positive_regulation of FLNA 29 0.59 13.88 3.97 49.36
101 INT8021 Gene_expression of Enpp1 43 0.78 31.46 10.8 48.24
102 INT16165 Regulation of DMD 114 0.60 35.13 3.64 45.44
103 INT224415 Gene_expression of CIMT 28 0.57 12.35 1.15 44.00
104 INT227457 Positive_regulation of Gene_expression of CIMT 9 0.15 3.19 0.54 44.00
105 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21 39.48
106 INT130186 Gene_expression of Ccl5 101 0.74 79.96 25.01 39.40
107 INT141612 Gene_expression of Ccr1 92 0.77 72.09 24.14 39.40
108 INT181418 Regulation of Gene_expression of Ccl5 11 0.52 9.86 3.37 39.40
109 INT189482 Regulation of Gene_expression of Ccr5 4 0.44 3.38 0.86 39.40
110 INT189481 Regulation of Gene_expression of Ccr1 3 0.45 1.97 0.58 39.40
111 INT189475 Regulation of Gene_expression of Ccr3 4 0.32 3.17 0.54 39.40
112 INT140342 Regulation of SGCB 3 0.11 4.27 1.25 37.04
113 INT113948 Gene_expression of FLNA 32 0.73 36.06 4.81 34.40
114 INT80779 Positive_regulation of Hbb-ar 10 0.41 2.48 3.29 32.64
115 INT937 Positive_regulation of Oxt 195 0.70 37.82 49.3 31.32
116 INT97901 Regulation of FGFR1 5 0.24 2.56 0.55 30.24
117 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 29.92
118 INT129508 Localization of Cacna1a 7 0.74 6.47 5.13 29.20
119 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 28.48
120 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 28.20
121 INT62156 Transcription of DMD 1 0.69 1.6 0 28.16
122 INT60723 Localization of Psen2 5 0.68 2.11 2.02 27.76
123 INT193856 Localization of Psen1 19 0.73 9.79 0.41 27.20
124 INT11625 Localization of App 98 0.78 55.46 20.86 26.80
125 INT97062 Binding of PML 10 0.41 11.63 1.65 26.56
126 INT259865 Gene_expression of Aibl 2 0.07 2.32 0.2 25.88
127 INT9191 Localization of EDN1 94 0.81 57.01 14.78 25.76
128 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 25.00
129 INT151684 Gene_expression of MCF2L 7 0.54 6.25 3.76 24.68
130 INT53475 Gene_expression of MRI1 116 0.59 77.68 33.98 24.32
131 INT333548 Binding of FES 1 0.08 0.17 0.04 23.92
132 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 21.28
133 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01 21.28
134 INT1766 Negative_regulation of PYCARD 25 0.37 6.54 6.76 17.04
135 INT195970 Binding of Atp1a2 2 0.34 2.31 1.66 16.44
136 INT228648 Binding of Scn1a 1 0.27 1.95 1.15 16.44
137 INT29635 Localization of Eno2 9 0.76 6.05 1.35 12.16
138 INT104756 Gene_expression of ACSM3 8 0.58 8.76 1.83 11.84
139 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07 11.08
140 INT174986 Gene_expression of AIRN 20 0.57 6.13 0.64 9.32
141 INT181042 Binding of Ccl5 18 0.41 9.34 4.51 9.04
142 INT56374 Gene_expression of AMBP 34 0.54 35.85 6.25 7.68
143 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
144 INT443 Localization of POMC 1020 0.81 284.52 443.17 5.00
145 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
146 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
147 INT6852 Localization of TNF 883 0.81 705.95 270.84 5.00
148 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 5.00
149 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
150 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
151 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
152 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
153 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 5.00
154 INT867 Gene_expression of IFNA1 930 0.78 594.85 168.03 5.00
155 INT9660 Regulation of TNF 363 0.62 312.94 139.99 5.00
156 INT6128 Positive_regulation of Localization of POMC 256 0.70 68.77 121.64 5.00
157 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 5.00
158 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 5.00
159 INT65500 Gene_expression of App 605 0.78 429.94 98.31 5.00
160 INT74058 Gene_expression of Nos1 260 0.78 80.04 95.71 5.00
161 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 5.00
162 INT6849 Localization of IL1B 229 0.81 112.56 69.63 5.00
163 INT102546 Gene_expression of Ccl2 197 0.78 192.8 67.41 5.00
164 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
165 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
166 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 5.00
167 INT46637 Gene_expression of CXCL10 172 0.78 121.94 57.74 5.00
168 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
169 INT20375 Gene_expression of Hand1 213 0.60 148.51 54.53 5.00
170 INT72182 Gene_expression of Mcpt1 167 0.75 123.7 52.15 5.00
171 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 5.00
172 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
173 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
174 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 5.00
175 INT5454 Localization of CRH 124 0.79 79.18 41.53 5.00
176 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
177 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
178 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 5.00
179 INT927 Gene_expression of Oxt 184 0.78 44.71 35.79 5.00
180 INT6484 Binding of IL1B 122 0.47 75.84 35.07 5.00
181 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 5.00
182 INT104392 Gene_expression of Cxcl10 113 0.75 106.86 34.12 5.00
183 INT11325 Gene_expression of HLA-E 209 0.76 98.05 33.72 5.00
184 INT52350 Gene_expression of CD14 184 0.75 71.37 33.13 5.00
185 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
186 INT35406 Localization of Tnf 94 0.81 64.63 31.65 5.00
187 INT124860 Gene_expression of Bace1 330 0.78 157.11 31.65 5.00
188 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 5.00
189 INT65960 Gene_expression of BCL2 352 0.78 312.03 30.73 5.00
190 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 5.00
191 INT11554 Negative_regulation of CSF2 129 0.59 108.55 29.44 5.00
192 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
193 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 5.00
194 INT3841 Gene_expression of FCGR3B 117 0.75 58.99 28.87 5.00
195 INT9199 Positive_regulation of CEBPZ 111 0.67 30.99 28.45 5.00
196 INT116861 Gene_expression of Apoe 182 0.78 100.41 27.26 5.00
197 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
198 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 5.00
199 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 5.00
200 INT151758 Gene_expression of PYCARD 91 0.63 14.54 24.27 5.00
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