D:Herpes Simplex Virus

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Disease Term
Synonyms Genus Simplex Virus, Herpes Labialis Virus, Herpes Simplex, Herpes Virus, Herpesvirus Facialis, Herpesvirus Hominis, HERPESVIRUS LABIALIS, HUMAN HERPESVIRUS 1, Human Herpesvirus Group 1, Simplex Virus
Documents 1092
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Herpes Simplex Virus. They are ordered first by their relevance to Herpes Simplex Virus and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT295722 PTGER2 Positive_regulation of RAC1 1 0.02 2.14 0.32 100.00
2 INT295725 PTGER2 Positive_regulation of RAC2 1 0.05 1.92 0.32 100.00
3 INT295710 PTGER2 Regulation of Positive_regulation of RAC1 1 0.01 1.62 0 99.98
4 INT295709 PTGER2 Regulation of VEGFA 1 0.01 1.61 0.41 99.70
5 INT218505 Binding of C5 and Cfb 1 0.01 0.29 0 99.38
6 INT295718 Binding of PTGER2 and Positive_regulation of Positive_regulation of SP1 1 0.02 0.58 0.04 97.04
7 INT295706 PTGER2 Regulation of Regulation of RHOA 1 0.01 0.61 0 96.68
8 INT295713 PTGER2 Positive_regulation of Regulation of CCL5 1 0.01 0.82 0.21 96.24
9 INT295715 PTGER2 Regulation of Localization of FGF2 1 0.02 0.6 0.05 96.12
10 INT295719 VEGFA Regulation of Localization of PTGER2 1 0.02 0.6 0.05 96.12
11 INT295723 VEGFA Regulation of Localization of FGF2 1 0.07 0.6 0.05 96.12
12 INT252633 Binding of TNF and Tnfrsf1b 4 0.05 3.66 1.54 95.76
13 INT308173 Binding of DRG1 and Tnfrsf1b 1 0.01 1.64 1.1 95.76
14 INT342688 Binding of Cap1 and Nav1 1 0.00 0.19 0.14 93.72
15 INT156161 Binding of HCFC1 and NFYC 1 0.02 0.36 0.12 93.56
16 INT356101 App Regulation of Negative_regulation of Psen1 1 0.23 0.31 0.04 93.04
17 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 91.60
18 INT299449 Foxl2 Regulation of Tpr 1 0.00 0.26 0 89.88
19 INT260858 IL6 Positive_regulation of Gene_expression of VEGFA 2 0.31 1.77 0.48 89.68
20 INT225649 IL4 Positive_regulation of Localization of DCPS 1 0.02 1.03 0.19 89.44
21 INT356110 Binding of App and Slc5a7 1 0.02 0.25 0.05 87.68
22 INT228137 Binding of Serpinb1-ps1 and Trav6-3 2 0.02 1.93 0.08 87.32
23 INT218498 Binding of C4b and Daf2 1 0.04 0.26 0 86.92
24 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 86.68
25 INT329310 Spp1 Positive_regulation of Gene_expression of IFN1@ 1 0.48 0.88 0.19 86.40
26 INT329309 Spp1 Regulation of Gene_expression of IFN1@ 1 0.26 0.82 0.19 86.40
27 INT308167 Binding of Eln and Tnfrsf1b 1 0.01 0.94 0.71 86.24
28 INT225629 APP Positive_regulation of Positive_regulation of nr 1 0.01 0.08 0 84.60
29 INT225627 APP Positive_regulation of nr 1 0.02 0.08 0 84.60
30 INT156162 Binding of HCFC1 and CREB3 1 0.13 0.35 0.22 83.36
31 INT295708 Binding of EGF and CCL2 1 0.01 0.79 0.49 83.20
32 INT193954 Binding of App and Psen1 3 0.38 0.88 0.06 82.48
33 INT156155 Binding of HCFC1 and TFAM 1 0.04 0.74 0.49 82.40
34 INT218532 Binding of C5 and LCN1 1 0.06 0.49 0 82.24
35 INT218506 Binding of LCN1 and Cfb 1 0.04 0.25 0 82.24
36 INT139849 Binding of App and Bace1 7 0.41 0.85 0.13 81.84
37 INT329305 Spp1 Positive_regulation of Gene_expression of Il12a 1 0.12 0.88 0.16 81.04
38 INT84921 Binding of NGF and NTRK1 13 0.50 6.39 6.1 80.92
39 INT156156 Positive_regulation of Binding of NGF and SMG1 1 0.03 0.41 0.26 80.92
40 INT156157 Binding of NGF and SMG1 1 0.02 0.4 0.23 80.92
41 INT295714 PTGER2 Positive_regulation of RHOA 1 0.01 0.34 0 80.84
42 INT273935 Crem Regulation of Gene_expression of Egr2 1 0.05 0.16 0.26 79.52
43 INT154716 Binding of MON1B and CD209 1 0.01 1.76 0.08 78.48
44 INT182839 Camk4 Positive_regulation of Creb1 3 0.49 1.81 0.79 78.24
45 INT329797 Positive_regulation of TLR2 Positive_regulation of Gene_expression of IL6 1 0.02 1.67 0.11 77.76
46 INT329802 Positive_regulation of TLR2 Regulation of Gene_expression of IL6 1 0.01 1.67 0.11 77.76
47 INT295755 Fgf2 Regulation of MMP9 1 0.07 0.99 0.33 77.28
48 INT295702 PTGER2 Positive_regulation of Racgap1 1 0.05 0.22 0 77.00
49 INT98379 Regulation of Binding of Pomc and Oprd1 1 0.01 0.35 0.23 76.92
50 INT98380 Binding of Pomc and Oprd1 1 0.02 0.35 0.23 76.92
51 INT295717 VEGFA Regulation of MMP9 1 0.01 0.98 0.33 76.88
52 INT285420 IRF6 Regulation of Localization of IL6 1 0.03 0.14 0 76.88
53 INT298257 Pou4f1 Negative_regulation of Proc 1 0.01 0.54 0.03 76.40
54 INT128869 Gabrg1 Positive_regulation of Transcription of Jun 1 0.09 0.55 0.62 75.00
55 INT137699 AR Regulation of PDYN 1 0.46 0.93 0.75 75.00
56 INT156160 TFAM Regulation of Gene_expression of NTRK1 1 0.03 0.39 0.27 74.32
57 INT156149 Binding of HCFC1 and POU4F1 1 0.27 0.39 0.28 73.48
58 INT156150 POU4F1 Regulation of Gene_expression of NTRK1 1 0.18 0.39 0.27 73.48
59 INT225648 IL4 Positive_regulation of Gene_expression of IL12A 1 0.06 0.89 0.03 73.04
60 INT299462 Binding of Mxd1 and Sin3a 1 0.08 0.62 0 72.92
61 INT299464 Binding of Mxd1 and SIDT1 1 0.11 0.31 0 72.76
62 INT299463 Binding of Sin3a and SIDT1 1 0.39 0.31 0 72.76
63 INT329304 Spp1 Negative_regulation of Gene_expression of Il10 1 0.06 0.93 0.13 72.00
64 INT225516 Ncoa6 Positive_regulation of D0Nrs1 1 0.04 0.3 0 68.96
65 INT285427 LBP Positive_regulation of Localization of IL8 1 0.10 0.19 0 68.44
66 INT185379 Binding of IRF6 and TLR2 4 0.08 2.88 0.35 68.40
67 INT185385 Binding of TLR2 and TLR4 3 0.27 3.63 0.32 68.40
68 INT182124 Binding of IRF6 and TLR4 14 0.10 16.11 4.65 68.04
69 INT156152 POU4F1 Positive_regulation of Positive_regulation of NTRK1 1 0.31 0.38 0.29 67.80
70 INT156154 POU4F1 Positive_regulation of HCFC1 1 0.36 0.38 0.28 67.80
71 INT253022 PTTG1 Negative_regulation of Negative_regulation of Trp53 1 0.03 1.34 0 67.36
72 INT180984 IRF6 Positive_regulation of Localization of IL8 7 0.11 2.13 3.47 67.20
73 INT225538 Binding of nr and D0Nrs1 1 0.00 0.07 0 67.12
74 INT348322 Il6 Positive_regulation of Localization of Crp 1 0.06 3.51 0.51 66.64
75 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 64.88
76 INT218511 Cfb Positive_regulation of C5 1 0.01 0.29 0.06 64.04
77 INT218503 Cfb Positive_regulation of C3 1 0.01 0.29 0.06 64.04
78 INT142947 Binding of ERCC2 and OPRM1 1 0.05 0.3 0.32 63.36
79 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03 62.76
80 INT329303 Spp1 Positive_regulation of Localization of Il12a 1 0.12 0.92 0.12 62.48
81 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 62.12
82 INT156151 POU4F1 Positive_regulation of Gene_expression of NTRK1 1 0.46 0.37 0.31 60.92
83 INT156163 POU4F1 Positive_regulation of NTRK1 1 0.46 0.37 0.31 60.92
84 INT140648 Binding of CRP and CCL11 1 0.14 0.88 0.13 60.72
85 INT156158 CREBZF Positive_regulation of Gene_expression of NTRK1 1 0.42 0.37 0.31 60.52
86 INT156159 CREBZF Positive_regulation of NTRK1 1 0.63 0.36 0.3 60.52
87 INT295720 PTGER2 Regulation of MMP9 1 0.01 0.53 0.7 60.40
88 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 0.06 1.2 0.25 60.00
89 INT228135 Positive_regulation of Trav6-3 Positive_regulation of Fasl 1 0.14 1.39 0 57.84
90 INT228138 Trav6-3 Positive_regulation of Fasl 1 0.14 1.38 0 57.84
91 INT166983 Binding of HLA-B and HSPG2 4 0.08 4.66 0.88 57.52
92 INT227773 Ctla4 Negative_regulation of Binding of Cd80 1 0.01 0.11 0 57.44
93 INT295711 MMP9 Positive_regulation of Localization of VEGFA 1 0.06 0.29 0.74 55.08
94 INT190775 Gene_expression of Il4 Negative_regulation of Positive_regulation of FOSL1 1 0.39 2.42 1.4 54.48
95 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04 50.96
96 INT331116 Binding of BLVRB and EBNA1BP2 1 0.04 0.38 0 50.16
97 INT295705 Binding of IK and TNF 1 0.00 0.27 0.64 50.00
98 INT295724 CXCL12 Positive_regulation of MMP9 1 0.02 0.32 0.6 50.00
99 INT295721 CSF2 Positive_regulation of MMP9 1 0.06 0.32 0.6 50.00
100 INT329068 Tlr9 Positive_regulation of Localization of IFNA1 1 0.03 1.54 0.19 50.00
101 INT329045 Binding of Unc93b1 and Tlr3 1 0.03 0.7 0.05 50.00
102 INT304757 Binding of HIVEP1 and ERVV-2 1 0.00 1.41 0.03 50.00
103 INT304756 Regulation of Binding of HIVEP1 and ERVV-2 1 0.00 1.46 0.03 50.00
104 INT295701 Positive_regulation of Binding of RAC1 and Racgap1 1 0.28 0.16 0 50.00
105 INT295704 Positive_regulation of Binding of RHOA and Racgap1 1 0.15 0.16 0 50.00
106 INT295700 Binding of RAC1 and Racgap1 1 0.21 0.16 0 50.00
107 INT295703 Binding of RHOA and Racgap1 1 0.11 0.16 0 50.00
108 INT172143 IL4 Positive_regulation of Protein_catabolism of TNF 2 0.11 1.7 0.69 49.20
109 INT172146 IL10 Positive_regulation of Protein_catabolism of TNF 2 0.15 1.69 0.69 49.20
110 INT172142 IL10 Positive_regulation of Protein_catabolism of IL1B 2 0.03 1.69 0.68 48.56
111 INT172132 IL4 Positive_regulation of Protein_catabolism of IL1B 2 0.02 1.69 0.68 48.56
112 INT285429 Binding of IRF6 and TLR6 1 0.08 0.1 0 47.76
113 INT285428 Binding of LTA and TLR6 1 0.08 0.1 0 45.40
114 INT285425 Binding of LTA and TLR4 1 0.09 0.1 0 45.40
115 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 43.36
116 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44 43.36
117 INT185756 Binding of ITIH4 and Cd4 2 0.05 1.22 0.04 43.00
118 INT174266 TNF Regulation of Gene_expression of F3 1 0.00 3.2 0.33 34.72
119 INT174265 IL18 Regulation of Gene_expression of F3 1 0.00 3.21 0.33 34.72
120 INT298267 Tcf3 Positive_regulation of Gene_expression of Runx1 1 0.21 0.6 0.1 30.08
121 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 29.80
122 INT342095 Regulation of Binding of Lat and Ie 1 0.07 2.03 0 29.72
123 INT340816 Tnfrsf14 Regulation of Gene_expression of Btla 1 0.11 1.09 0.18 29.64
124 INT340822 Trav6-3 Regulation of Gene_expression of Btla 1 0.07 0.97 0.15 29.64
125 INT235968 NMO-IgG Positive_regulation of Nqo1 1 0.00 2.11 0.03 27.68
126 INT342094 Binding of Lat and Ie 1 0.05 1.9 0 27.64
127 INT333969 Binding of TNF and Cd4 1 0.03 1.28 0.39 24.24
128 INT305038 CD99 Regulation of DES 1 0.12 1.25 0 17.96
129 INT260439 Positive_regulation of Binding of IFNA1 and Il6 1 0.01 1.08 0.07 17.48
130 INT260442 Binding of IFNA1 and Il6 1 0.01 1.07 0.07 16.80
131 INT342693 Binding of Prkaca and Gopc 1 0.01 0.23 0.48 15.84
132 INT319921 Binding of HLA-DOA and ITIH4 1 0.00 0.07 0 14.64
133 INT298256 Runx1 Positive_regulation of Negative_regulation of Ntrk1 1 0.30 0.55 0.16 13.20
134 INT298293 Runx1 Positive_regulation of Negative_regulation of Ntrk2 1 0.52 0.54 0.16 12.56
135 INT298273 Binding of Pou4f1 and target gene site 1 0.01 0.53 0.18 9.24
136 INT225542 Binding of D0Nrs1 and Asc2 1 0.01 0.63 0 5.32
137 INT225601 Binding of D0Nrs1 and Ncoa6 1 0.04 0.84 0 5.32
138 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
139 INT26824 Crh Positive_regulation of Localization of Penk 7 0.54 0.42 6.49 5.00
140 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
141 INT179502 Binding of Cd14 and Tlr4 29 0.39 13.77 5.73 5.00
142 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 5.00
143 INT85743 Pdyn Positive_regulation of Oprk1 3 0.32 2.12 3.52 5.00
144 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
145 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
146 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
147 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
148 INT114134 Penk Positive_regulation of Oprm1 2 0.24 1.48 2.68 5.00
149 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
150 INT284860 Binding of Pdzd2 and Nav1 9 0.29 2.33 2.34 5.00
151 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
152 INT157767 Binding of TLR4 and LY96 8 0.54 4.05 1.95 5.00
153 INT199486 Oprm1 Regulation of Gene_expression of Oprd1 1 0.02 0.49 1.84 5.00
154 INT199287 TNF Positive_regulation of Transcription of Oprm1 2 0.02 1.86 1.8 5.00
155 INT199503 ENG Positive_regulation of Oprk1 1 0.01 0.87 1.69 5.00
156 INT45306 Pomc Positive_regulation of ENG 2 0.07 1.11 1.68 5.00
157 INT199504 ENG Positive_regulation of Oprm1 1 0.01 0.87 1.68 5.00
158 INT199497 Pdyn Negative_regulation of Il1 1 0.00 0.14 1.67 5.00
159 INT199490 Penk Positive_regulation of Oprk1 1 0.03 0.87 1.64 5.00
160 INT199501 Pdyn Positive_regulation of Oprm1 1 0.01 0.86 1.63 5.00
161 INT215096 Binding of Hmgb1 and Tlr2 9 0.38 11.61 1.61 5.00
162 INT190772 Il4 Negative_regulation of Gene_expression of Ptger2 1 0.03 1.28 1.49 5.00
163 INT298283 Pou4f1 Positive_regulation of Gene_expression of Runx1 1 0.50 1.4 1.48 5.00
164 INT190773 Il4 Negative_regulation of Gene_expression of Ptgs2 1 0.06 1.26 1.45 5.00
165 INT190774 Il4 Negative_regulation of Positive_regulation of Ptgs2 1 0.06 1.26 1.45 5.00
166 INT199494 Crh Positive_regulation of Localization of Pdyn 1 0.02 0.43 1.4 5.00
167 INT15846 Crh Positive_regulation of Localization of ENG 3 0.07 0.42 1.38 5.00
168 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3 5.00
169 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 5.00
170 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27 5.00
171 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 5.00
172 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23 5.00
173 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22 5.00
174 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
175 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19 5.00
176 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18 5.00
177 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
178 INT199493 Ngf Regulation of Oprd1 1 0.05 1.05 1.15 5.00
179 INT231769 TNF Negative_regulation of Gene_expression of HMOX1 1 0.26 4.75 1.15 5.00
180 INT308172 Rvm Positive_regulation of Phosphorylation of GRIN1 1 0.50 0.68 1.14 5.00
181 INT190771 Gene_expression of Il4 Negative_regulation of Gene_expression of Mapk14 1 0.15 1.14 1.13 5.00
182 INT190770 Il4 Negative_regulation of Gene_expression of Mapk14 1 0.20 1.14 1.13 5.00
183 INT173059 Binding of KDR and VEGFA 43 0.43 29.63 1.1 5.00
184 INT298272 Runx1 Positive_regulation of Gene_expression of Ntrk3 1 0.52 0.88 1.09 5.00
185 INT298292 Runx3 Positive_regulation of Gene_expression of Ntrk3 1 0.35 1.36 1.09 5.00
186 INT239038 Negative_regulation of Binding of Cd28 and Cd86 3 0.17 1.5 1.05 5.00
187 INT182125 Binding of CD14 and TLR4 7 0.25 3.78 1.03 5.00
188 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
189 INT298298 Calca Negative_regulation of Gene_expression of Runx1 1 0.19 0.33 1 5.00
190 INT298274 Gene_expression of Runx1 Negative_regulation of Calca 1 0.19 0.33 1 5.00
191 INT308169 Negative_regulation of Mapk14 Negative_regulation of Ltp 1 0.01 0.79 0.95 5.00
192 INT219154 Binding of HMGB1 and TLR4 2 0.17 4.45 0.93 5.00
193 INT291011 Pomc Regulation of Gene_expression of ENG 1 0.08 0.86 0.91 5.00
194 INT224583 CSF2 Positive_regulation of IL1RN 1 0.02 1.3 0.88 5.00
195 INT284855 Binding of S100a10 and Nav1 4 0.21 0.99 0.88 5.00
196 INT224585 IL1B Positive_regulation of IL1RN 1 0.02 1.3 0.87 5.00
197 INT298289 Runx1 Negative_regulation of Ntrk2 1 0.60 1.09 0.87 5.00
198 INT199499 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.8 0.86 5.00
199 INT199492 Il6 Positive_regulation of Transcription of Oprm1 1 0.01 0.81 0.86 5.00
200 INT199487 Il6 Positive_regulation of Oprm1 1 0.01 0.8 0.86 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Herpes Simplex Virus. They are ordered first by their pain relevance and then by number of times they were reported in Herpes Simplex Virus. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT1760 Gene_expression of PTGER2 524 0.57 226.94 96.4 100.00
2 INT58390 Negative_regulation of Localization of PTGER2 25 0.21 14.4 4.25 100.00
3 INT129207 Gene_expression of Cxcl1 114 0.75 68.54 30.82 100.00
4 INT10837 Positive_regulation of Gene_expression of IL8 294 0.70 190.08 70.34 100.00
5 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
6 INT108485 Gene_expression of CXCL12 61 0.75 49.34 13.79 100.00
7 INT78899 Gene_expression of CCL5 155 0.77 84.02 55.09 100.00
8 INT100005 Binding of MITF 7 0.47 6.93 0.44 100.00
9 INT1209 Binding of Kitl 14 0.37 6.72 4.3 100.00
10 INT217807 Regulation of MITF 20 0.00 18.57 0.36 100.00
11 INT50212 Gene_expression of Ifx 33 0.75 32.17 7.26 100.00
12 INT98376 Gene_expression of tk 27 0.51 21.9 2.23 100.00
13 INT130647 Regulation of Gene_expression of CXCL12 6 0.39 5.01 1.38 100.00
14 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 100.00
15 INT229561 Gene_expression of Flt3l 5 0.65 16.76 0.27 100.00
16 INT199077 Localization of Racgap1 7 0.73 2.43 0.42 100.00
17 INT85348 Localization of RHOA 12 0.59 4.81 1.83 100.00
18 INT45155 Negative_regulation of Polymerase 18 0.51 15.18 1.38 100.00
19 INT97280 Gene_expression of Tk1 11 0.77 16.17 1.32 100.00
20 INT172170 Gene_expression of HV1S 3 0.04 2.59 0.93 100.00
21 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 100.00
22 INT317145 Negative_regulation of D9Mgi9 1 0.01 1.16 0 100.00
23 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 100.00
24 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 100.00
25 INT187851 Gene_expression of Hbb-ar 40 0.65 16.34 2.3 100.00
26 INT16385 Regulation of C3 20 0.41 9.98 1.92 100.00
27 INT105162 Gene_expression of Ad 47 0.12 46.53 1.83 100.00
28 INT27115 Binding of Mbp 8 0.31 3.01 0.48 100.00
29 INT49108 Gene_expression of TP53TG3 6 0.43 6.02 0.35 100.00
30 INT185394 Binding of PVRL1 5 0.14 2.94 0.09 100.00
31 INT308254 Negative_regulation of Binding of PVRL1 1 0.01 1.02 0 100.00
32 INT1761 Positive_regulation of PTGER2 135 0.49 90.17 26.26 99.98
33 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.98
34 INT1765 Positive_regulation of Gene_expression of PTGER2 140 0.51 68.68 27 99.98
35 INT1763 Regulation of Gene_expression of PTGER2 43 0.36 23.98 10.95 99.98
36 INT35486 Regulation of PTGER2 39 0.36 19.03 6.75 99.98
37 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.98
38 INT187190 Positive_regulation of Localization of MMP9 27 0.68 8.1 8.93 99.98
39 INT47651 Gene_expression of DERL2 7 0.68 7.85 0.38 99.98
40 INT67568 Positive_regulation of Localization of MMP2 14 0.31 8.58 6.79 99.98
41 INT279394 Positive_regulation of Localization of IK 5 0.09 2.67 1.03 99.98
42 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.98
43 INT295688 Positive_regulation of Regulation of MMP9 1 0.14 0.67 1.51 99.98
44 INT285448 Positive_regulation of Gene_expression of TLR7 4 0.61 2.58 0.5 99.98
45 INT93734 Positive_regulation of Gene_expression of Bcl2 76 0.70 61.95 18.46 99.98
46 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 99.96
47 INT22434 Gene_expression of Ads1 10 0.75 9.16 1.4 99.96
48 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 99.92
49 INT60728 Gene_expression of Serpinb1-ps1 10 0.59 6.92 0.93 99.92
50 INT26546 Positive_regulation of Gene_expression of Hras1 35 0.70 16.59 4.54 99.92
51 INT13510 Gene_expression of ERBB2 530 0.78 405.68 16.79 99.92
52 INT7056 Positive_regulation of Gene_expression of PENK 35 0.70 14.31 18.21 99.86
53 INT35487 Localization of PTGER2 103 0.46 51.24 17.45 99.84
54 INT58393 Positive_regulation of Localization of PTGER2 37 0.25 16.8 6 99.84
55 INT798 Positive_regulation of Gene_expression of Penk 394 0.70 78.53 203.07 99.84
56 INT295681 Positive_regulation of CDC42EP1 1 0.01 2.63 0 99.84
57 INT2289 Gene_expression of PENK 203 0.78 55.62 79.49 99.84
58 INT29708 Gene_expression of Gria1 177 0.78 56.36 77.37 99.84
59 INT25122 Binding of PTGER2 31 0.31 13.83 3.12 99.84
60 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 99.84
61 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 99.84
62 INT154115 Positive_regulation of Localization of PENK 5 0.49 3.15 6.93 99.84
63 INT200435 Binding of polymerase 6 0.16 5.56 0.47 99.84
64 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.82
65 INT34487 Localization of MMP2 56 0.81 31.41 23.61 99.82
66 INT113987 Localization of IK 29 0.23 16.73 8.25 99.82
67 INT234717 Regulation of Cxcl1 10 0.41 6.14 2.9 99.82
68 INT219180 Gene_expression of TLR7 13 0.68 9.51 2.21 99.82
69 INT796 Gene_expression of Penk 1902 0.78 275.47 1057.59 99.80
70 INT203 Positive_regulation of Pomc 257 0.70 90.56 92.84 99.80
71 INT156097 Negative_regulation of Localization of VEGFA 70 0.58 34.96 4.17 99.78
72 INT91417 Positive_regulation of PTGES 36 0.68 18.45 7.64 99.78
73 INT295685 Positive_regulation of Localization of CCL15 1 0.05 1.31 0.91 99.78
74 INT291371 Positive_regulation of Localization of CXCL12 2 0.35 2.8 0.65 99.78
75 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 99.78
76 INT84825 Gene_expression of CD36 121 0.78 43.73 33.23 99.78
77 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 99.78
78 INT206158 Regulation of CDC42EP1 3 0.01 1.44 0.14 99.76
79 INT78895 Regulation of CCL5 30 0.46 20.45 10.18 99.72
80 INT16258 Gene_expression of Ntf3 121 0.78 53.93 59.03 99.70
81 INT4887 Gene_expression of Tac4 70 0.77 11.66 40.97 99.70
82 INT75224 Positive_regulation of Gene_expression of Ntf3 23 0.69 11.79 13.08 99.70
83 INT4890 Gene_expression of Ppt1 51 0.77 8.93 21.83 99.70
84 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77 99.68
85 INT102021 Positive_regulation of Gene_expression of Creb1 66 0.70 24.04 23.28 99.68
86 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 99.66
87 INT4862 Localization of PENK 62 0.81 11.57 40.28 99.66
88 INT78479 Negative_regulation of Localization of PENK 2 0.43 1.9 1.81 99.66
89 INT89282 Regulation of MMP9 39 0.60 25.45 10.34 99.64
90 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.64
91 INT218463 Negative_regulation of Binding of Cfb 7 0.08 2.31 0.28 99.64
92 INT218474 Negative_regulation of Binding of C5 1 0.06 0.53 0 99.64
93 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.62
94 INT99610 Localization of MMP9 126 0.79 48.46 32.67 99.62
95 INT58392 Regulation of Localization of PTGER2 10 0.25 5.18 2.19 99.62
96 INT61866 Positive_regulation of Gene_expression of Vta1 6 0.36 5.02 7.88 99.62
97 INT60758 Gene_expression of Prkce 8 0.20 4.12 4.59 99.58
98 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 99.56
99 INT100400 Localization of CCL17 3 0.61 3.42 3.46 99.54
100 INT295676 Localization of CCL8 3 0.49 6.05 2.11 99.54
101 INT8732 Positive_regulation of Gene_expression of Oprm1 76 0.70 22.59 58.83 99.54
102 INT181422 Localization of CCL15 2 0.22 1.76 1.62 99.54
103 INT295692 Localization of CCL7 1 0.06 1.22 0.89 99.54
104 INT78901 Localization of CCL5 67 0.78 40.79 20.59 99.54
105 INT728 Positive_regulation of Penk 1068 0.70 186.9 636.87 99.52
106 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 99.52
107 INT53081 Negative_regulation of Gene_expression of Ptgs2 29 0.59 15.83 10.39 99.52
108 INT130646 Regulation of CXCL12 14 0.47 7.67 3.48 99.50
109 INT99767 Regulation of THBS1 18 0.42 11.51 1.03 99.48
110 INT245089 Localization of CXCL12 8 0.65 10.17 1.28 99.48
111 INT173589 Localization of OSM 4 0.58 1.65 1.07 99.48
112 INT14690 Localization of CSF2 124 0.80 85.17 27.26 99.48
113 INT2640 Gene_expression of Pomc 424 0.78 120.72 155.37 99.48
114 INT63419 Gene_expression of PTGES 109 0.77 40.83 23.67 99.46
115 INT21502 Gene_expression of Scn4a 22 0.78 4.47 7.97 99.46
116 INT252993 Negative_regulation of THBS1 8 0.55 6.93 0.59 99.44
117 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 99.44
118 INT100021 Localization of Tnfrsf1b 7 0.80 3.4 1.96 99.44
119 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 99.42
120 INT96270 Gene_expression of D9Mit120 1 0.03 1.99 0.65 99.42
121 INT184378 Binding of Cfb 54 0.20 12.49 2.36 99.38
122 INT6507 Binding of C5 23 0.48 15.35 3.91 99.38
123 INT8152 Gene_expression of Vta1 40 0.58 19.9 46.28 99.36
124 INT5895 Gene_expression of Oprm1 525 0.78 120.67 407.29 99.36
125 INT29709 Positive_regulation of Gene_expression of Gria1 36 0.69 9.43 17.83 99.36
126 INT56686 Regulation of Vta1 26 0.44 3.43 24.48 99.36
127 INT300351 Negative_regulation of S100A2 1 0.32 2.17 0 99.32
128 INT114511 Positive_regulation of Gene_expression of Gria2 14 0.41 3.9 4.71 99.32
129 INT58283 Localization of ABCC1 8 0.23 6.07 2.08 99.28
130 INT20705 Positive_regulation of Scn4a 18 0.68 4.34 7.85 99.26
131 INT295678 Regulation of Positive_regulation of RAC1 1 0.23 1.55 0 99.16
132 INT105393 Positive_regulation of Localization of VEGFA 66 0.70 45.45 4.9 99.16
133 INT82292 Negative_regulation of ABCC1 8 0.59 1.55 1.39 99.16
134 INT71152 Negative_regulation of NTRK1 15 0.59 10.28 5.5 99.16
135 INT2780 Regulation of Gene_expression of Penk 265 0.62 32.45 143.88 99.14
136 INT68683 Regulation of Gene_expression of VEGFA 143 0.62 104.19 20.14 99.14
137 INT7692 Positive_regulation of PENK 71 0.70 20.34 32.54 99.14
138 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 99.12
139 INT121967 Regulation of RAC1 9 0.45 6.14 3.41 99.12
140 INT142949 Gene_expression of FPR2 27 0.71 26.17 5.58 99.12
141 INT48238 Regulation of Gene_expression of Ngf 25 0.62 11.48 16.42 99.10
142 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 99.06
143 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 99.06
144 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 99.02
145 INT150852 Positive_regulation of Localization of Cxcl1 5 0.51 2.82 1.72 99.02
146 INT17313 Positive_regulation of HSPG2 57 0.67 55.78 16.65 99.02
147 INT99606 Negative_regulation of Localization of MMP9 23 0.57 7.15 5.47 99.00
148 INT78619 Positive_regulation of RAC1 27 0.65 10.43 3.75 98.98
149 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 98.98
150 INT56525 Gene_expression of Gria2 74 0.75 23.15 28.6 98.98
151 INT27954 Positive_regulation of Gene_expression of Ngf 87 0.70 57.91 51.96 98.90
152 INT300360 Negative_regulation of PRG1 1 0.32 2.16 0 98.88
153 INT14624 Gene_expression of Pax3 100 0.38 33.22 69.47 98.88
154 INT27739 Positive_regulation of EGF 49 0.70 28.31 13.68 98.84
155 INT106153 Gene_expression of HJURP 5 0.04 2.33 1.85 98.84
156 INT11062 Positive_regulation of MME 24 0.63 14.37 5.26 98.72
157 INT24326 Gene_expression of Ngf 346 0.78 218.67 184.71 98.70
158 INT295694 Localization of DNAI1 4 0.15 3.28 1.09 98.68
159 INT150856 Localization of Cxcl1 14 0.78 6.97 4.91 98.68
160 INT58400 Negative_regulation of Tnf 182 0.59 129.97 71 98.66
161 INT69952 Positive_regulation of IK 45 0.32 16.08 14.59 98.64
162 INT159632 Localization of DCPS 24 0.21 18.24 6.8 98.64
163 INT92592 Transcription of PTGER2 6 0.32 4.52 0.47 98.60
164 INT63932 Positive_regulation of Ephb1 537 0.70 259.67 296.14 98.60
165 INT62373 Negative_regulation of NGF 34 0.59 25.87 22.38 98.56
166 INT73048 Gene_expression of MMP9 268 0.77 159.75 57.81 98.48
167 INT126031 Negative_regulation of Gene_expression of MMP9 40 0.57 22.71 9.79 98.48
168 INT93715 Negative_regulation of MMP9 69 0.55 36.05 11.73 98.48
169 INT77434 Positive_regulation of Gene_expression of Nos2 151 0.69 96.76 38.94 98.44
170 INT21214 Negative_regulation of Gene_expression of PENK 21 0.58 9.14 9.53 98.36
171 INT295611 Regulation of DNAI1 5 0.23 2.41 0.87 98.34
172 INT186798 Regulation of TLR3 5 0.42 3.13 0.69 98.32
173 INT128769 Negative_regulation of Localization of IFNA1 8 0.24 6.85 1.35 98.24
174 INT55583 Localization of IFNA1 135 0.78 85.07 24.13 98.24
175 INT6656 Gene_expression of YY1 135 0.75 24.73 72.16 98.20
176 INT66280 Gene_expression of Nos2 534 0.78 330.78 157.07 98.12
177 INT26500 Gene_expression of MMP2 201 0.78 110.57 46.9 98.08
178 INT295683 Positive_regulation of RAC2 1 0.49 1.72 0.3 98.08
179 INT34488 Negative_regulation of MMP2 85 0.59 41.98 21.72 98.08
180 INT96581 Negative_regulation of Negative_regulation of MMP2 4 0.57 3.1 1.04 98.08
181 INT48928 Positive_regulation of Gene_expression of Mapk1 19 0.48 9.38 6.59 98.04
182 INT48925 Gene_expression of Mapk1 95 0.74 42.21 32.91 98.04
183 INT103238 Localization of PTGES 7 0.68 4.16 2.59 97.94
184 INT167735 Positive_regulation of DNAI1 2 0.49 2.88 0.52 97.88
185 INT125411 Negative_regulation of Phosphorylation of Mapk14 31 0.57 18.55 19.98 97.88
186 INT94953 Negative_regulation of Mapk14 156 0.59 104.77 91.51 97.88
187 INT91948 Positive_regulation of Prkce 16 0.64 11.36 10.32 97.82
188 INT160440 Positive_regulation of Crem 48 0.69 20.38 7.66 97.80
189 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 97.72
190 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 97.72
191 INT69029 Gene_expression of PTPRC 127 0.75 74.26 11.57 97.68
192 INT7532 Negative_regulation of Gene_expression of Ifng 33 0.59 18.56 13.14 97.60
193 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15 97.60
194 INT128178 Positive_regulation of RHOA 59 0.68 9.3 4.7 97.52
195 INT114406 Gene_expression of Adora1 28 0.72 6.83 9.13 97.48
196 INT87314 Gene_expression of Htt 112 0.78 55.82 3.03 97.46
197 INT31774 Positive_regulation of Vta1 67 0.44 14.52 71.79 97.42
198 INT58484 Regulation of Il4 12 0.45 8.67 6.09 97.40
199 INT54272 Regulation of Insig1 5 0.30 2.42 2.14 97.40
200 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 97.36
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