D:Inclusion Body Myositis

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pChart

Disease Term
Synonyms Inclusion Body Myopathy Sporadic, Inclusion Body Myositides, Inclusion Body Myositis Sporadic, MYOPATHY INCLUSION BODY SPORADIC, Myositides Inclusion Body, Myositis Inclusion Body Sporadic, Sporadic Inclusion Body Myositis
Documents 33
Hot Single Events 8
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Inclusion Body Myositis. They are ordered first by their relevance to Inclusion Body Myositis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT316769 Binding of H2-K1 and Hspa9 1 0.08 1.02 0.15 5.00
2 INT316773 Esr1 Positive_regulation of Ddit3 1 0.02 0.41 0.03 5.00
3 INT316774 Hsp90b1 Positive_regulation of Localization of Ddit3 1 0.12 0.17 0 5.00
4 INT316770 Hsp90b1 Positive_regulation of Ddit3 1 0.12 0.17 0 5.00
5 INT264683 Binding of VAPB and ALS2 1 0.29 1.1 0 5.00
6 INT264679 IGFALS Positive_regulation of CTSC 1 0.02 1.68 0 5.00
7 INT316772 Calr Positive_regulation of Ddit3 1 0.10 0.12 0 5.00
8 INT316771 Calr Positive_regulation of Localization of Ddit3 1 0.10 0.12 0 5.00
9 INT264678 Binding of SETX and KRT20 1 0.00 2.17 0 5.00
10 INT264682 Binding of VAPB and SETX 1 0.28 1.09 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Inclusion Body Myositis. They are ordered first by their pain relevance and then by number of times they were reported in Inclusion Body Myositis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT154525 Localization of IBM3 1 0.57 1.31 0.12 100.00
2 INT154524 Gene_expression of IBM3 1 0.52 1.3 0.12 100.00
3 INT29745 Binding of APP 47 0.48 26.49 12.4 99.60
4 INT16814 Negative_regulation of COX5A 74 0.57 33.72 28.63 98.84
5 INT47712 Positive_regulation of App 135 0.69 101.38 28.94 97.14
6 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 88.08
7 INT65500 Gene_expression of App 605 0.78 429.94 98.31 81.36
8 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 81.36
9 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 76.88
10 INT29743 Negative_regulation of App 91 0.59 65.56 31.26 73.60
11 INT14572 Binding of INS 205 0.48 175.43 13.38 65.36
12 INT69396 Gene_expression of H2-K1 72 0.65 38.16 4.56 25.00
13 INT6660 Positive_regulation of Jun 148 0.69 67.58 29.73 14.60
14 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
15 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
16 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 5.00
17 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
18 INT4960 Positive_regulation of CSF2 285 0.70 256.73 65.73 5.00
19 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 5.00
20 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 5.00
21 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 5.00
22 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
23 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 5.00
24 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
25 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
26 INT37296 Binding of Esr1 117 0.43 62.51 27.33 5.00
27 INT44954 Gene_expression of APP 191 0.78 105.86 23.9 5.00
28 INT102112 Gene_expression of Prnp 440 0.78 209.32 22.5 5.00
29 INT78057 Localization of Tlr4 140 0.77 67.75 21.72 5.00
30 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 5.00
31 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 5.00
32 INT69569 Positive_regulation of Prnp 175 0.70 96.31 13.34 5.00
33 INT2038 Localization of Esr1 104 0.79 40.12 13.27 5.00
34 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 5.00
35 INT4605 Negative_regulation of Gene_expression of INS 220 0.58 139.66 10.75 5.00
36 INT46273 Gene_expression of PRNP 103 0.78 110.34 9.25 5.00
37 INT23178 Gene_expression of H1 38 0.68 13.37 9.09 5.00
38 INT67037 Gene_expression of Sod1 121 0.78 59.32 7.99 5.00
39 INT9818 Positive_regulation of Pdia4 12 0.34 0.67 6.65 5.00
40 INT38672 Binding of KRT20 69 0.39 48.01 6.31 5.00
41 INT179744 Negative_regulation of SLC1A2 16 0.45 12.32 6.14 5.00
42 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 5.00
43 INT125066 Negative_regulation of HDAC4 56 0.49 41.55 5.42 5.00
44 INT135436 Gene_expression of Hspa9 31 0.62 14.75 5.2 5.00
45 INT102254 Positive_regulation of Gene_expression of Prnp 72 0.70 38.11 4.81 5.00
46 INT118565 Gene_expression of Ddit3 35 0.75 23.62 4.32 5.00
47 INT170455 Gene_expression of Atp8a1 66 0.75 24.63 3.94 5.00
48 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83 5.00
49 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 5.00
50 INT227523 Localization of Hspa9 9 0.60 5.26 3.18 5.00
51 INT160251 Gene_expression of Myo5a 48 0.63 37.14 3.16 5.00
52 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88 5.00
53 INT171117 Binding of Itgam 35 0.36 14.87 2.76 5.00
54 INT11476 Positive_regulation of H2-K1 17 0.26 9.48 2.23 5.00
55 INT195968 Positive_regulation of Gene_expression of Hsp90b1 10 0.49 5.21 2.02 5.00
56 INT210709 Regulation of Itgam 8 0.28 9.21 1.76 5.00
57 INT163998 Gene_expression of CTSC 9 0.65 11.24 1.69 5.00
58 INT98687 Gene_expression of Calr 38 0.61 7.03 1.59 5.00
59 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45 5.00
60 INT105569 Binding of IGFALS 13 0.25 17.31 1.36 5.00
61 INT137382 Negative_regulation of Gene_expression of KRT20 22 0.58 12.29 1.29 5.00
62 INT66118 Binding of Calr 4 0.46 1.46 1.26 5.00
63 INT74443 Positive_regulation of PML 11 0.53 12.52 1.21 5.00
64 INT221213 Negative_regulation of Hspa9 7 0.34 2.79 1.18 5.00
65 INT284669 Gene_expression of LRRK2 3 0.65 4.58 1.14 5.00
66 INT116140 Localization of Ddit3 2 0.57 1.94 0.96 5.00
67 INT240280 Gene_expression of IGFALS 14 0.42 20.38 0.95 5.00
68 INT192785 Regulation of Myo5a 4 0.05 9.05 0.93 5.00
69 INT192496 Positive_regulation of Gene_expression of H2-K1 13 0.26 8.44 0.92 5.00
70 INT227521 Regulation of Gene_expression of Hspa9 2 0.36 2.25 0.92 5.00
71 INT69397 Regulation of Gene_expression of H2-K1 9 0.23 6.32 0.91 5.00
72 INT227520 Positive_regulation of Gene_expression of Hspa9 4 0.40 4.16 0.83 5.00
73 INT261203 Binding of HTs 5 0.32 3.01 0.71 5.00
74 INT160799 Regulation of IGFALS 11 0.29 9.09 0.7 5.00
75 INT232841 Gene_expression of Scap 11 0.02 8.68 0.7 5.00
76 INT133386 Positive_regulation of PNKD 2 0.45 1.71 0.69 5.00
77 INT256673 Positive_regulation of Hsp90b1 12 0.49 8.49 0.68 5.00
78 INT227522 Regulation of Hspa9 4 0.39 1.85 0.66 5.00
79 INT177557 Positive_regulation of Calr 12 0.48 5.47 0.61 5.00
80 INT240281 Positive_regulation of IGFALS 11 0.31 10.44 0.56 5.00
81 INT256690 Binding of Hsp90b1 11 0.30 5.94 0.55 5.00
82 INT222077 Regulation of Hsp90b1 9 0.37 4.78 0.45 5.00
83 INT264689 Negative_regulation of IGFALS 10 0.33 12.58 0.45 5.00
84 INT96520 Gene_expression of PRPH 5 0.75 2.55 0.39 5.00
85 INT222080 Regulation of Gene_expression of Hsp90b1 3 0.50 1.22 0.34 5.00
86 INT264684 Regulation of Gene_expression of TARDBP 1 0.41 4.21 0.31 5.00
87 INT264685 Gene_expression of TARDBP 4 0.61 8.8 0.31 5.00
88 INT264687 Binding of TARDBP 1 0.33 4.14 0.31 5.00
89 INT315353 Localization of H2-K1 2 0.30 1.28 0.31 5.00
90 INT123622 Negative_regulation of Vcp 5 0.42 2.51 0.3 5.00
91 INT251949 Negative_regulation of Gene_expression of PRNP 6 0.43 4.16 0.3 5.00
92 INT240278 Localization of IGFALS 11 0.53 9.44 0.29 5.00
93 INT316764 Localization of Hsp90b1 1 0.53 1.53 0.28 5.00
94 INT247952 Binding of H2-K1 4 0.09 3.32 0.28 5.00
95 INT264686 Positive_regulation of Gene_expression of IGFALS 2 0.28 2.21 0.27 5.00
96 INT316765 Regulation of Localization of Hsp90b1 1 0.32 0.95 0.25 5.00
97 INT316768 Regulation of Localization of H2-K1 1 0.11 0.95 0.25 5.00
98 INT222087 Regulation of Calr 3 0.42 0.56 0.22 5.00
99 INT116432 Positive_regulation of Positive_regulation of SOD1 3 0.40 3.88 0.2 5.00
100 INT227511 Binding of Hspa9 2 0.30 0.28 0.19 5.00
101 INT316763 Positive_regulation of Positive_regulation of Hspa9 1 0.40 1.7 0.17 5.00
102 INT230874 Gene_expression of C9 4 0.23 1.88 0.16 5.00
103 INT290795 Gene_expression of Slc2a2 3 0.44 1.22 0.16 5.00
104 INT177555 Regulation of Gene_expression of Calr 3 0.28 0.82 0.16 5.00
105 INT177554 Positive_regulation of Gene_expression of Calr 3 0.37 1.08 0.14 5.00
106 INT237045 Positive_regulation of Vcp 7 0.62 6.96 0.12 5.00
107 INT316767 Regulation of Positive_regulation of Hspa9 1 0.36 0.89 0.12 5.00
108 INT316749 Gene_expression of Chd4 1 0.65 0.55 0.07 5.00
109 INT230875 Binding of C9 2 0.11 1.2 0.06 5.00
110 INT316761 Positive_regulation of Binding of Hsp90b1 1 0.35 0.8 0.05 5.00
111 INT316762 Binding of Ddit3 1 0.11 0.14 0.04 5.00
112 INT284672 Gene_expression of ZFAND2B 1 0.11 1.03 0.04 5.00
113 INT316766 Negative_regulation of Calr 2 0.40 0.71 0.03 5.00
114 INT284671 Binding of HOOK2 1 0.06 0.16 0 5.00
115 INT284670 Localization of LRRK2 3 0.78 2.22 0 5.00
116 INT185299 Gene_expression of PNKD 5 0.22 6.35 0 5.00
117 INT284603 Localization of Vcp 1 0.73 0.82 0 5.00
118 INT284668 Positive_regulation of Gene_expression of LRRK2 1 0.16 0.86 0 5.00
119 INT256680 Negative_regulation of Hsp90b1 4 0.47 1.43 0 5.00
120 INT230876 Localization of C9 2 0.22 0.43 0 5.00
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