D:Intellectual Impairment

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pChart

Disease Term
Synonyms Deficiencies Mental, Deficiency Mental, Idiocy, Intellectual Deterioration, Intelligence, Intelligence Quotient, Low Iq, Mental Deficiencies, Mental Deficiency, Mental Retardation, Mental Retardation Psychosocial
Documents 1393
Hot Single Events 200
Hot Interactions 16

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Intellectual Impairment. They are ordered first by their relevance to Intellectual Impairment and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT327333 Binding of TNF and Fxr1 1 0.06 3.74 0.48 99.96
2 INT297848 Binding of Fzd4 and Ndp 1 0.04 1.19 0 99.92
3 INT297855 Binding of Ndp and Wnt1 1 0.38 1.18 0 99.92
4 INT204494 Binding of App and Fmr1 1 0.54 4.39 0.54 95.20
5 INT122927 Ntrk1 Positive_regulation of SPTLC1 1 0.00 0.65 0.09 95.16
6 INT302364 Binding of Arx and Reln 1 0.32 1.25 0 92.28
7 INT302370 Binding of Arx and Dcx 1 0.35 1.25 0 92.28
8 INT302373 Binding of Arx and Tuba1a 1 0.30 1.26 0 92.28
9 INT302368 Binding of Arx and Pafah1b1 1 0.27 1.25 0 92.28
10 INT95125 Binding of KCNA6 and SGCG 1 0.40 2.73 0.18 90.16
11 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18 87.92
12 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18 87.92
13 INT204488 Binding of Fmr1 and Ncl 1 0.12 0.61 0 87.40
14 INT317900 Binding of NCAPH2 and MCPH1 1 0.02 0.53 0 86.92
15 INT341628 Binding of ADAR and PROC 1 0.03 5.01 0 81.60
16 INT82023 Binding of Ntrk1 and Ngf 5 0.53 3.48 3.92 81.44
17 INT353848 Binding of SCLY and Ubash3a 1 0.30 0.47 0.04 77.96
18 INT355327 Binding of Nes and Prom1 1 0.11 1.49 0.06 76.76
19 INT221952 UTS2R Regulation of Protein_catabolism of CDK5R1 1 0.10 0.3 0.04 76.64
20 INT234795 Negative_regulation of CHM Negative_regulation of RAB27A 1 0.01 0.8 0 75.04
21 INT287612 Binding of Fmr1 and Dnajc13 1 0.01 0.84 0 74.56
22 INT344221 Binding of C4bp and Krt1 1 0.01 0.5 0 74.00
23 INT344227 Binding of C4b and Krt1 1 0.01 0.51 0 74.00
24 INT204497 Fmr1 Regulation of Positive_regulation of Gria1 1 0.04 1.75 0.14 72.20
25 INT204489 Fmr1 Regulation of App 1 0.50 1.71 0.13 72.20
26 INT182804 Binding of ETV3 and T2DM 1 0.10 2.62 0 72.16
27 INT234800 RAB27A Positive_regulation of INS 1 0.02 1.26 0 71.64
28 INT234793 RAB27A Positive_regulation of Localization of INS 1 0.03 1.26 0 71.64
29 INT328143 Gabrb3 Positive_regulation of Ube3a 1 0.56 0.99 0.11 70.64
30 INT328146 Gabrb3 Negative_regulation of Ube3a 1 0.48 0.99 0.11 70.64
31 INT127155 MAA Negative_regulation of Uqcrc2 1 0.00 0.5 0.08 70.04
32 INT303248 LILRA3 Positive_regulation of Protein_catabolism of Psd 1 0.01 0.2 0.03 68.40
33 INT159132 Klf9 Positive_regulation of Smc5 1 0.01 0.48 0.2 67.64
34 INT246466 GHS Positive_regulation of GHS Regulation of Gh 1 0.01 0.6 0.1 65.88
35 INT246468 GHS Regulation of Gh 1 0.05 1.12 0.19 65.56
36 INT182778 IGF1 Positive_regulation of Gene_expression of ETV3 1 0.03 1.89 0 63.52
37 INT182783 INS Positive_regulation of Gene_expression of ETV3 1 0.01 1.89 0 63.52
38 INT182777 IAPP Positive_regulation of Gene_expression of ETV3 1 0.06 1.88 0 63.52
39 INT191612 Nf1 Positive_regulation of ras 1 0.25 2.6 0.11 63.16
40 INT234801 RAB3GAP1 Regulation of RAB3A 1 0.08 1.64 0.15 62.48
41 INT182784 IGF1 Positive_regulation of Gene_expression of INS 1 0.02 1.87 0 61.76
42 INT182776 IAPP Positive_regulation of Gene_expression of INS 1 0.03 1.87 0 61.76
43 INT271071 Binding of ACTA1 and Hypism 1 0.00 1.54 0.15 61.28
44 INT272593 Dlg4 Positive_regulation of Clc 1 0.11 0.54 0.04 60.80
45 INT272599 Dlg4 Positive_regulation of Gene_expression of Clc 1 0.11 0.54 0.04 60.80
46 INT272598 Dlg4 Positive_regulation of Gene_expression of Gria2 1 0.03 0.53 0.04 60.08
47 INT272591 Dlg4 Positive_regulation of Gene_expression of Clybl 1 0.09 0.53 0.04 60.08
48 INT199667 Cep290 Regulation of Atf4 1 0.04 1.96 0.09 58.88
49 INT272590 Dlg4 Positive_regulation of Clybl 1 0.09 0.52 0.04 58.80
50 INT221961 Binding of ELAVL1 and UTS2R 1 0.00 0.26 0.03 58.24
51 INT199666 Cntln Regulation of Atf4 1 0.00 1.95 0.09 58.16
52 INT246467 GHS Regulation of Localization of Gh 1 0.03 0.52 0.09 56.76
53 INT327340 Binding of TNF and Hnrnpd 1 0.03 1.02 0.25 56.40
54 INT327300 Binding of Hnrnpd and Myc 1 0.12 1.02 0.25 56.00
55 INT328150 H2-Q13 Positive_regulation of Gene_expression of Ube3a 1 0.55 1.23 0.07 53.40
56 INT328148 H2-Q13 Positive_regulation of Ube3a 1 0.55 1.23 0.07 53.40
57 INT328145 H2-Q13 Positive_regulation of Atp10a 1 0.54 1.23 0.07 53.40
58 INT328144 H2-Q13 Positive_regulation of Gene_expression of Atp10a 1 0.54 1.23 0.07 53.40
59 INT151546 Adcy1 Positive_regulation of Atf2 1 0.36 0.37 0.37 53.16
60 INT151545 Adcy1 Positive_regulation of Regulation of Fmr1 1 0.48 0.37 0.37 53.16
61 INT151549 Regulation of Adcy1 Positive_regulation of Atf2 1 0.33 0.37 0.37 53.16
62 INT151544 Camk4 Positive_regulation of Regulation of Fmr1 1 0.50 0.36 0.37 52.84
63 INT151551 Regulation of Camk4 Positive_regulation of Atf2 1 0.34 0.36 0.37 52.84
64 INT151547 Camk4 Positive_regulation of Atf2 1 0.38 0.36 0.37 52.84
65 INT221953 UTS2R Positive_regulation of Gene_expression of CDK5R1 1 0.16 0.23 0.04 52.60
66 INT221959 Binding of CDK5 and CDK5R1 1 0.28 0.53 0.1 51.68
67 INT298858 Positive_regulation of Binding of VAPA and RILP 1 0.07 0.54 0 51.36
68 INT298847 Binding of VAPA and RILP 1 0.05 0.54 0 51.36
69 INT341896 Oxt Regulation of Localization of POMC 1 0.07 0.91 0.19 50.00
70 INT192618 Atrx Regulation of Gene_expression of Hba-a1 1 0.08 0.45 0 50.00
71 INT180294 Positive_regulation of Binding of CPB1 and S100B 1 0.09 0 0 48.48
72 INT180302 Positive_regulation of Binding of S100B and Tg(EGFR)0Jlj 1 0.05 0 0 48.48
73 INT234831 Binding of SPTLC1 and Abo 1 0.00 1.61 0.23 47.08
74 INT221963 ELAVL1 Regulation of Gene_expression of CDK5R1 1 0.01 0.58 0.03 47.00
75 INT287609 Fmr1 Regulation of Protein_catabolism of Dlg4 1 0.05 0.06 0 43.44
76 INT287619 Fmr1 Regulation of Dlg4 1 0.12 0.06 0 43.44
77 INT180303 Binding of S100B and Tg(EGFR)0Jlj 1 0.03 0 0 42.40
78 INT180295 Binding of CPB1 and S100B 1 0.08 0 0 42.08
79 INT346746 Binding of Cacng2 and Gria2 1 0.21 0.18 0 40.84
80 INT346764 Binding of RBM10 and Gria2 1 0.01 0.18 0 40.44
81 INT191614 Adcyap1 Positive_regulation of Rtcd1 1 0.01 0.93 0 40.24
82 INT241614 CCNA2 Regulation of PRB3 1 0.06 0 0.37 40.12
83 INT264209 Binding of Igh-Lev and Sv2a 1 0.17 1.78 0.38 40.04
84 INT341895 Oxt Positive_regulation of Localization of POMC 1 0.08 0.49 0.15 37.80
85 INT234802 Binding of AQP2 and AVPR2 2 0.15 0.84 0.07 36.64
86 INT234791 Binding of AVP and AVPR2 1 0.14 0.55 0 36.64
87 INT234796 Binding of AQP2 and AVP 1 0.15 1.1 0 36.64
88 INT262942 Binding of PAX6 and SOX2 1 0.18 0.9 0 36.56
89 INT262943 Regulation of Binding of PAX6 and SOX2 1 0.17 0.91 0 36.56
90 INT262938 Binding of PAX6 and SIX3 1 0.13 0.9 0 35.84
91 INT262940 Regulation of Binding of PAX6 and SIX3 1 0.16 0.91 0 35.84
92 INT221962 UTS2R Regulation of Gene_expression of CDK5R1 1 0.09 0.43 0.03 32.48
93 INT298845 VAPA Regulation of Negative_regulation of RAB7A 1 0.12 0.32 0 31.60
94 INT298864 VAPB Regulation of Negative_regulation of RAB7A 1 0.32 0.32 0 31.60
95 INT262939 PAX6 Regulation of CDH4 1 0.02 0.97 0.08 30.28
96 INT262937 PAX6 Regulation of CDH8 1 0.03 0.98 0.08 30.28
97 INT262944 PAX6 Regulation of CDH6 1 0.03 0.97 0.08 30.28
98 INT197467 Binding of Dpcd and Memor1 1 0.00 0.12 0 30.24
99 INT318920 Binding of XIAP and COMMD1 1 0.12 0.78 0 30.24
100 INT320400 Binding of Vcp and Khdrbs1 1 0.01 0.07 0 29.96
101 INT127156 HSD17B10 Regulation of Acaa2 1 0.02 0 0.12 25.84
102 INT204478 Fmr1 Regulation of Gene_expression of App 1 0.50 1.44 0.16 25.80
103 INT303170 Gene_expression of Trim3 Negative_regulation of Shank1 1 0.40 0.12 0.04 23.92
104 INT298876 RAB7A Positive_regulation of Protein_catabolism of NTRK1 1 0.14 0.44 0.22 22.56
105 INT277892 IDS Regulation of Ids 1 0.18 0.41 0 22.52
106 INT355330 Regulation of Gtf3a Regulation of Gene_expression of Tg(CAG-EGFP)D4Nagy 1 0.00 0.9 0.12 21.44
107 INT347815 Binding of TBATA and Naq1 1 0.00 0 0 20.56
108 INT221956 CDK5R1 Regulation of Positive_regulation of CDK5 1 0.21 0.62 0.19 16.96
109 INT327321 Binding of Elavl1 and Nos2 1 0.05 0.6 0.24 16.56
110 INT327320 Positive_regulation of Binding of Elavl1 and Nos2 1 0.06 0.6 0.24 16.56
111 INT303177 Trim3 Positive_regulation of Protein_catabolism of Dlgap1 1 0.41 0.13 0.05 16.40
112 INT234797 AVP Regulation of GOPC 1 0.01 0.65 0 16.16
113 INT234803 AVP Regulation of AQP2 1 0.11 1.3 0 15.96
114 INT324053 Binding of Banf1 and Lemd3 1 0.20 0.15 0 15.92
115 INT303161 Gene_expression of Trim3 Positive_regulation of Shank1 1 0.44 0 0 15.68
116 INT287606 Binding of Fxr1 and Fxr2 1 0.32 0 0 15.36
117 INT327315 S100a8 Negative_regulation of Binding of Khsrp 1 0.01 0.55 0.21 14.00
118 INT204477 Binding of App and Scn10a 1 0.17 0.36 0.1 13.76
119 INT303172 Binding of Dlgap1 and Trim3 1 0.22 0.13 0.13 10.40
120 INT303249 Binding of LILRA3 and Dlgap1 1 0.01 0.13 0.05 10.40
121 INT303247 Binding of LILRA3 and Trim3 1 0.01 0.13 0.05 9.68
122 INT174104 Binding of HSPG2 and Ache 1 0.16 0.98 0.09 6.68
123 INT191617 Binding of Nf1 and Rtcd1 1 0.01 0.95 0.08 6.12
124 INT191613 Binding of Nf1 and Rasa1 1 0.06 0.88 0.03 6.12
125 INT15984 Binding of Avp and Oxt 11 0.32 1.33 3.64 5.00
126 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
127 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
128 INT191618 Binding of App and Nf1 1 0.35 3.77 1.65 5.00
129 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3 5.00
130 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3 5.00
131 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2 5.00
132 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18 5.00
133 INT262336 Binding of Abat and Tmem132a 1 0.00 1.39 1.14 5.00
134 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
135 INT341897 Positive_regulation of NT5C3 Positive_regulation of Positive_regulation of Oxt 1 0.32 0.42 1.07 5.00
136 INT338894 TNFSF14 Negative_regulation of Gsk3a 1 0.00 0.54 1.04 5.00
137 INT144108 Binding of SLC6A3 and SLC6A4 1 0.12 0.64 1.03 5.00
138 INT338892 TNFSF14 Regulation of Abat 1 0.00 0.61 1.01 5.00
139 INT338895 TNFSF14 Regulation of Regulation of Abat 1 0.00 0.62 1.01 5.00
140 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99 5.00
141 INT338893 TNFSF14 Positive_regulation of Gene_expression of Gria1 1 0.07 0.59 0.94 5.00
142 INT271635 Negative_regulation of GRIN1 Negative_regulation of Positive_regulation of Ltp 1 0.00 0.65 0.93 5.00
143 INT281482 Drd2 Positive_regulation of Drd2 Positive_regulation of Penk 1 0.21 0.27 0.87 5.00
144 INT90387 ROS1 Positive_regulation of NFKB1 4 0.32 2.35 0.87 5.00
145 INT197470 Binding of Sostdc1 and Hbtq 1 0.00 0.87 0.87 5.00
146 INT228255 Binding of Akt1 and Pten 2 0.43 1.78 0.8 5.00
147 INT232621 Binding of Gria1 and Psd 1 0.10 0.29 0.77 5.00
148 INT252145 Binding of Napb and Snap25 9 0.19 0.85 0.75 5.00
149 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 5.00
150 INT232620 Ptpn4 Regulation of Cysltr1 1 0.02 0.58 0.68 5.00
151 INT232617 Grid2ip Regulation of Cysltr1 1 0.03 0.58 0.68 5.00
152 INT232613 Gopc Regulation of Cysltr1 1 0.02 0.58 0.68 5.00
153 INT232615 Psd Regulation of Cysltr1 1 0.02 0.58 0.68 5.00
154 INT232622 Magi2 Regulation of Cysltr1 1 0.01 0.58 0.67 5.00
155 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
156 INT327334 Il10 Negative_regulation of TNF 1 0.02 1.46 0.6 5.00
157 INT327323 Il10 Positive_regulation of Gene_expression of Ttpa 1 0.02 1.43 0.58 5.00
158 INT327339 Gtf3a Positive_regulation of VEGFA 1 0.00 2.34 0.58 5.00
159 INT259184 Binding of Gria2 and Gria1 2 0.26 0.28 0.54 5.00
160 INT255463 Binding of Avp and Avpr1a 1 0.06 0.67 0.54 5.00
161 INT209152 Regulation of OXT Positive_regulation of PNLIP 1 0.05 0.42 0.54 5.00
162 INT267707 Binding of Tnf and ARID1B 2 0.20 8.2 0.54 5.00
163 INT354367 Binding of FGFR1 and Tlr4 1 0.01 1.23 0.53 5.00
164 INT232618 Gene_expression of Grid2ip Regulation of Localization of Gria1 1 0.28 0.86 0.52 5.00
165 INT327332 VEGFA Positive_regulation of Gene_expression of Hgfac 1 0.00 2.02 0.49 5.00
166 INT339275 Il6 Regulation of KRT20 1 0.00 3.11 0.49 5.00
167 INT189859 Binding of SLC6A3 and ADHD1 2 0.32 0.68 0.48 5.00
168 INT341428 EPO Positive_regulation of NGF 1 0.52 0.37 0.48 5.00
169 INT341427 EPO Positive_regulation of BDNF 1 0.52 0.36 0.48 5.00
170 INT232619 Binding of Gria1 and Grid2ip 1 0.23 0.51 0.48 5.00
171 INT341426 EPO Regulation of NGF 1 0.51 0.5 0.47 5.00
172 INT341425 EPO Regulation of BDNF 1 0.51 0.5 0.47 5.00
173 INT343642 Adp Positive_regulation of Localization of Hspg2 1 0.01 0 0.44 5.00
174 INT302369 Binding of Arx and Dlx1 1 0.34 0 0.43 5.00
175 INT343643 Adp Positive_regulation of Positive_regulation of Hspg2 1 0.01 0 0.43 5.00
176 INT191610 Binding of App and Drd3 1 0.20 0.7 0.42 5.00
177 INT241679 EIF2AK3 Positive_regulation of Atf4 1 0.06 0.46 0.4 5.00
178 INT343640 Positive_regulation of Grm5 Positive_regulation of Adp 1 0.01 0 0.4 5.00
179 INT177396 Npy1r Positive_regulation of Negative_regulation of Npy 1 0.27 0.38 0.37 5.00
180 INT177400 RNY1 Positive_regulation of Negative_regulation of Npy 1 0.03 0.38 0.37 5.00
181 INT302371 Dlx1 Regulation of Gene_expression of Arx 1 0.28 0 0.35 5.00
182 INT327308 Binding of Elavl1 and Ttpa 1 0.02 1.73 0.34 5.00
183 INT272602 Binding of Dlg4 and Gria2 3 0.09 0.19 0.34 5.00
184 INT344923 Binding of CEBPZ and GOPC 1 0.06 0.24 0.33 5.00
185 INT190683 Binding of A2M and INS 4 0.11 4.97 0.32 5.00
186 INT191616 Binding of Cbln1 and Nf1 1 0.01 0.2 0.32 5.00
187 INT191620 Binding of Nf1 and Gopc 1 0.08 0.2 0.32 5.00
188 INT290614 Binding of Th and RLS 1 0.21 3.26 0.31 5.00
189 INT232614 Positive_regulation of Car2 Positive_regulation of Cysltr1 1 0.01 0.62 0.31 5.00
190 INT232616 Car2 Positive_regulation of Cysltr1 1 0.02 0.62 0.31 5.00
191 INT191611 Nf1 Regulation of ras 1 0.26 0.18 0.3 5.00
192 INT150050 Mtor Positive_regulation of Rps6kb1 3 0.49 1.44 0.3 5.00
193 INT339002 Binding of OPRD1 and GSX1 1 0.00 0 0.3 5.00
194 INT327328 Binding of Hnrnpd and Elavl1 1 0.06 0.74 0.3 5.00
195 INT339000 Binding of LMOD1 and GSX1 1 0.01 0 0.3 5.00
196 INT252140 Binding of Cck and Snap25 1 0.30 0.39 0.3 5.00
197 INT339001 GSX1 Positive_regulation of ADCY1 1 0.01 0 0.29 5.00
198 INT354368 FGFR1 Positive_regulation of Tlr4 1 0.01 0.16 0.29 5.00
199 INT279265 Binding of MEFV and NLRP3 1 0.07 2.79 0.28 5.00
200 INT327337 MIR29A Negative_regulation of Ttpa 1 0.04 1.14 0.28 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Intellectual Impairment. They are ordered first by their pain relevance and then by number of times they were reported in Intellectual Impairment. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT204463 Gene_expression of Fmr1 50 0.78 23.73 0.78 100.00
2 INT151539 Negative_regulation of Fmr1 9 0.59 11.85 0.87 100.00
3 INT151543 Binding of Fmr1 56 0.48 19.4 1.65 100.00
4 INT204468 Negative_regulation of Gene_expression of Fmr1 5 0.59 7.5 0.19 100.00
5 INT302374 Binding of DLG3 1 0.04 1.08 0 100.00
6 INT154104 Binding of ARID1B 47 0.39 69.82 1.49 100.00
7 INT184803 Localization of TSC1 5 0.37 6.13 0.32 100.00
8 INT310681 Negative_regulation of ARSB 1 0.56 6.95 0.29 100.00
9 INT81353 Gene_expression of Fmr1 2 0.68 1.89 0.24 100.00
10 INT338869 Regulation of Regulation of Fmr1 1 0.11 0.29 0.15 100.00
11 INT338870 Regulation of Fmr1 1 0.14 0.29 0.14 100.00
12 INT322758 Positive_regulation of Localization of TSC1 1 0.06 1.4 0 100.00
13 INT260048 Binding of PCDH19 1 0.37 4.77 0 99.96
14 INT297823 Gene_expression of Ndp 1 0.63 2.51 0 99.92
15 INT2155 Negative_regulation of Sst 111 0.59 16.58 77.74 99.80
16 INT34058 Gene_expression of FMR1 5 0.75 5.11 0.26 99.76
17 INT15091 Gene_expression of SLC6A4 101 0.78 29.91 53.64 99.68
18 INT68695 Gene_expression of HTT 63 0.77 44.54 3.69 99.68
19 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 99.66
20 INT36675 Negative_regulation of Pepd 3 0.47 8.99 0.63 99.60
21 INT217 Negative_regulation of Th 134 0.59 26.83 62.63 99.60
22 INT155195 Negative_regulation of THRSP 1 0.01 0.27 0.07 99.60
23 INT108710 Gene_expression of HAL 36 0.58 14.75 2.16 99.52
24 INT186895 Localization of PC 5 0.65 1.16 0.3 99.42
25 INT214 Localization of AVP 370 0.81 208.51 91.09 99.36
26 INT247263 Regulation of Mecp2 4 0.60 1.31 1.32 99.32
27 INT338882 Regulation of Regulation of Mecp2 1 0.24 0.56 0.29 99.32
28 INT234817 Gene_expression of GDI1 4 0.17 2.99 0.25 99.26
29 INT260050 Gene_expression of PCDH19 1 0.77 12.52 0.09 99.20
30 INT260049 Negative_regulation of PCDH19 1 0.58 4.41 0.04 99.20
31 INT277258 Localization of Satb2 1 0.81 3.59 0.04 99.14
32 INT260051 Positive_regulation of PCDH19 1 0.69 1.69 0 99.04
33 INT172574 Gene_expression of Pcp4 1 0.33 0.26 0 98.98
34 INT19804 Negative_regulation of Hprt 18 0.59 20.6 2.17 98.96
35 INT13960 Gene_expression of GGT6 5 0.62 4.18 3.01 98.88
36 INT83411 Binding of Ntrk1 6 0.19 3.7 3.74 98.88
37 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 98.68
38 INT147079 Gene_expression of Ext2 2 0.66 1.04 0.1 98.68
39 INT301360 Gene_expression of Ext1 3 0.68 1.01 0 98.68
40 INT9140 Negative_regulation of PFKM 14 0.59 12.67 3.61 98.64
41 INT243872 Negative_regulation of Gene_expression of DLGAP1 1 0.21 1.18 0.06 98.60
42 INT243878 Gene_expression of DLGAP1 1 0.38 1.17 0.06 98.60
43 INT53487 Gene_expression of TSC1 81 0.58 77.71 7.94 98.40
44 INT322756 Negative_regulation of Tsc1 1 0.07 1.4 0.26 98.06
45 INT1894 Negative_regulation of Localization of Gh 168 0.58 64.12 43.56 98.00
46 INT265823 Binding of WHSC1 1 0.08 1.17 0 97.92
47 INT259867 Binding of SCN1A 2 0.36 4.7 0.21 97.92
48 INT94650 Gene_expression of Grm5 32 0.77 11.26 14.82 97.92
49 INT328133 Localization of Gabrb3 1 0.75 1.35 0.27 97.92
50 INT114969 Gene_expression of CDK5R1 3 0.75 11.24 1.33 97.88
51 INT300926 Gene_expression of OBFC1 15 0.65 6.97 1.22 97.88
52 INT224815 Gene_expression of PRELID1 1 0.09 0.5 0 97.88
53 INT103246 Positive_regulation of Protein_catabolism of COL7A1 8 0.34 8.67 3.03 97.88
54 INT97779 Negative_regulation of TSC2 3 0.41 3.45 0.26 97.88
55 INT224813 Positive_regulation of Gene_expression of PRELID1 1 0.06 0.27 0 97.88
56 INT16714 Regulation of Creb1 64 0.62 22.23 33.56 97.84
57 INT338872 Regulation of Regulation of Creb1 1 0.21 0.28 0.15 97.84
58 INT34952 Regulation of ABAT 28 0.61 6.05 14.39 97.80
59 INT334577 Binding of KCNE1L 1 0.27 1.33 0 97.60
60 INT1893 Localization of Gh 1041 0.79 340.23 256.58 97.56
61 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 97.44
62 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 97.44
63 INT125399 Negative_regulation of Nat2 1 0.01 1.84 0.72 97.40
64 INT214073 Binding of TSC1 9 0.37 22 1.34 97.24
65 INT95789 Positive_regulation of Grm5 42 0.55 20.1 33.72 97.12
66 INT231152 Regulation of Dmd 9 0.47 3.64 0.19 97.12
67 INT111345 Negative_regulation of Cbs 2 0.30 2.82 0.36 97.04
68 INT203646 Gene_expression of STIP1 26 0.63 23.57 1.14 96.88
69 INT107129 Positive_regulation of RLS 46 0.60 40.1 8.09 96.82
70 INT180626 Gene_expression of spc 6 0.34 6.83 0.15 96.72
71 INT148564 Localization of HAL 8 0.68 2.46 0.62 96.62
72 INT243881 Negative_regulation of SHANK3 1 0.34 1.16 0.06 96.60
73 INT243863 Negative_regulation of Binding of SHANK3 1 0.34 1.16 0.06 96.60
74 INT243874 Negative_regulation of Binding of NLGN1 1 0.41 1.16 0.06 96.60
75 INT243865 Negative_regulation of NLGN1 1 0.41 1.15 0.06 96.60
76 INT243866 Negative_regulation of CYTIP 1 0.05 1.09 0.06 96.60
77 INT84026 Positive_regulation of SLC7A7 8 0.67 3.12 0.33 96.52
78 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34 96.48
79 INT100383 Binding of FRA10AC1 2 0.01 1.2 0.42 96.28
80 INT54492 Negative_regulation of Otc 4 0.43 1.19 0.88 96.24
81 INT244103 Localization of DOCK3 1 0.32 0.26 0 96.04
82 INT187362 Binding of PST 4 0.30 1.48 0.82 95.88
83 INT221978 Regulation of Gene_expression of CDK5R1 1 0.59 5.08 0.61 95.84
84 INT151540 Regulation of Fmr1 8 0.59 6.08 1.34 95.84
85 INT6638 Binding of Oxtr 14 0.34 1.52 2.43 95.84
86 INT151536 Regulation of Regulation of Fmr1 1 0.43 0.53 0.33 95.84
87 INT298884 Binding of RAB7A 1 0.45 9.82 0.14 95.80
88 INT22873 Positive_regulation of ELN 6 0.45 3.74 0.33 95.80
89 INT298906 Negative_regulation of Binding of RAB7A 1 0.40 0.99 0 95.80
90 INT201261 Regulation of AGFG1 4 0.09 2.72 0.9 95.76
91 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 95.56
92 INT5363 Negative_regulation of PEPD 11 0.56 6.49 3.11 95.48
93 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 95.48
94 INT95767 Negative_regulation of Mmp9 72 0.57 49.14 17.1 95.48
95 INT324044 Negative_regulation of Lemd3 1 0.43 2.86 0 95.32
96 INT158326 Phosphorylation of Tie1 1 0.16 0.8 0.45 95.20
97 INT56918 Negative_regulation of TAT 11 0.57 5.92 2.44 95.16
98 INT187364 Localization of PST 3 0.60 2.1 0.7 95.08
99 INT221972 Regulation of CDK5 1 0.42 1.87 0.16 95.00
100 INT7506 Negative_regulation of Ltp 267 0.46 91.01 176.8 94.80
101 INT77662 Regulation of CDK5R1 2 0.60 1.93 0.63 94.80
102 INT246463 Negative_regulation of GHS 2 0.17 2.73 0.75 94.80
103 INT118673 Regulation of Camk4 12 0.48 7.92 5.22 94.80
104 INT118676 Positive_regulation of Camk4 34 0.70 16.67 10.9 94.80
105 INT69259 Gene_expression of Pst 7 0.54 4.11 2.69 94.72
106 INT204460 Positive_regulation of Gene_expression of Fmr1 7 0.61 6.19 0.03 94.44
107 INT66041 Positive_regulation of NTRK1 24 0.70 16.12 8.42 94.36
108 INT243868 Binding of NLGN1 1 0.36 1.09 0.06 94.32
109 INT183714 Gene_expression of EMG1 17 0.60 1.59 0.19 94.16
110 INT107916 Protein_catabolism of App 114 1.00 66.71 12.38 94.16
111 INT151538 Positive_regulation of Fmr1 21 0.68 12.24 2.07 94.12
112 INT20950 Positive_regulation of PC 12 0.60 2.76 1.19 94.04
113 INT303215 Regulation of Apc2 1 0.09 0.28 0.03 94.04
114 INT245785 Negative_regulation of NDUFS4 1 0.06 1.16 0.09 94.00
115 INT192608 Regulation of Atrx 1 0.39 0.67 0 93.92
116 INT33358 Gene_expression of Cysltr1 46 0.62 24.18 13.36 93.92
117 INT243871 Binding of SHANK3 1 0.30 1.09 0.06 93.88
118 INT204452 Binding of Fxr1 10 0.40 4.48 0.45 93.88
119 INT82177 Negative_regulation of H2-Q10 5 0.58 5.83 0.45 93.84
120 INT175423 Positive_regulation of TSC1 25 0.36 21.81 0.45 93.82
121 INT14572 Binding of INS 205 0.48 175.43 13.38 93.72
122 INT142118 Regulation of Gene_expression of Runx2 2 0.61 2.92 0 93.60
123 INT5095 Localization of Ghrh 185 0.81 28.09 62.08 93.40
124 INT115039 Positive_regulation of FMR1 4 0.49 2.26 0.46 93.34
125 INT216104 Positive_regulation of Gene_expression of Dmd 23 0.46 4.52 0.68 93.32
126 INT92311 Regulation of SIL1 7 0.44 6.2 1.61 93.16
127 INT1599 Positive_regulation of ADCY1 146 0.67 30.05 64.9 93.08
128 INT12617 Regulation of ADCY1 41 0.61 7.38 15.94 93.08
129 INT13179 Regulation of Positive_regulation of ADCY1 5 0.34 0.89 3.08 93.08
130 INT21632 Positive_regulation of Adh1 32 0.70 15.67 11.65 93.04
131 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 92.92
132 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 92.56
133 INT68267 Gene_expression of CACNA1A 22 0.75 11.39 8.65 92.32
134 INT122930 Positive_regulation of Gene_expression of CACNA1A 2 0.49 0.91 0.54 92.32
135 INT91821 Binding of Cacna1a 16 0.48 13.1 6.37 92.28
136 INT11258 Gene_expression of Gnas 58 0.58 21.6 6.33 92.08
137 INT113107 Phosphorylation of Hist1h3f 21 0.51 8.01 4.45 92.00
138 INT26273 Negative_regulation of RYR1 18 0.43 7.64 3.11 91.96
139 INT228669 Positive_regulation of Localization of Vim 1 0.12 0.34 0.07 91.96
140 INT106525 Phosphorylation of Akt1 436 0.82 183.81 47.82 91.92
141 INT36777 Gene_expression of CTD 12 0.41 11.47 1.42 91.92
142 INT303239 Gene_expression of Trim3 1 0.76 0.77 0.93 91.88
143 INT199222 Gene_expression of SAMSN1 14 0.57 18.97 1.61 91.84
144 INT73354 Gene_expression of Gap43 36 0.77 13.74 7.47 91.84
145 INT320432 Protein_catabolism of Ube3a 1 0.42 0.55 0.24 91.76
146 INT320436 Positive_regulation of Protein_catabolism of Ube3a 1 0.21 0.42 0.04 91.76
147 INT63839 Binding of CRS 31 0.41 34.05 4.7 91.68
148 INT15490 Negative_regulation of Gene_expression of COL7A1 40 0.58 25.97 7.18 91.60
149 INT166698 Localization of Vim 3 0.18 1.13 0.4 91.60
150 INT303192 Gene_expression of Trim9 1 0.32 0.28 0 91.48
151 INT277257 Binding of Satb2 1 0.37 2.51 0 91.44
152 INT320364 Protein_catabolism of Huwe1 1 0.24 0.54 0.24 91.36
153 INT14717 Gene_expression of TAT 20 0.75 10.67 3.66 91.36
154 INT59119 Positive_regulation of ADCYAP1 9 0.69 4.68 2.48 91.28
155 INT217955 Negative_regulation of Negative_regulation of DARC 1 0.06 0.38 0.05 91.24
156 INT204448 Localization of Hnrnpa2b1 1 0.12 0.68 0 91.16
157 INT2038 Localization of Esr1 104 0.79 40.12 13.27 91.08
158 INT48313 Binding of NTRK1 19 0.47 14.44 6.12 91.04
159 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 91.04
160 INT38788 Negative_regulation of CYSLTR1 8 0.42 4.5 1.16 90.92
161 INT56268 Negative_regulation of Gene_expression of F8a1 2 0.02 1.29 0.52 90.72
162 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 90.64
163 INT20275 Negative_regulation of Abo 13 0.20 4.62 4.02 90.64
164 INT182800 Positive_regulation of ETV3 5 0.46 10.01 0.14 90.60
165 INT182754 Positive_regulation of T2DM 1 0.67 4.5 0.03 90.60
166 INT103959 Gene_expression of ATP1A2 3 0.67 2.47 1.68 90.24
167 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42 90.20
168 INT318967 Gene_expression of Mecp2 9 0.77 11.52 3.55 90.12
169 INT143833 Positive_regulation of Foxc1 2 0.42 1.02 0.09 90.04
170 INT143832 Positive_regulation of Barx1 1 0.19 0.86 0.09 90.04
171 INT143834 Positive_regulation of Pitx2 1 0.22 0.86 0.09 90.04
172 INT53906 Positive_regulation of Negative_regulation of Gh 9 0.50 6.72 2.73 89.96
173 INT257835 Negative_regulation of Btk 6 0.41 2.41 0.16 89.92
174 INT143835 Gene_expression of Foxc1 2 0.39 1.17 0.09 89.92
175 INT143836 Negative_regulation of Foxc1 1 0.35 0.92 0.09 89.92
176 INT72040 Binding of L1cam 14 0.48 3.57 1.97 89.84
177 INT297836 Negative_regulation of Ndp 1 0.41 1.8 0 89.72
178 INT64965 Binding of AGFG1 8 0.10 3.53 0.45 89.64
179 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 89.48
180 INT692 Negative_regulation of SST 72 0.59 28.68 34.52 89.48
181 INT143830 Gene_expression of Barx1 1 0.23 0.91 0.09 89.48
182 INT143831 Negative_regulation of Barx1 1 0.16 0.91 0.09 89.48
183 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 89.24
184 INT57163 Gene_expression of AGFG1 11 0.75 2.45 0.48 89.24
185 INT114499 Gene_expression of MCPH1 38 0.67 26.68 4.55 89.20
186 INT143837 Negative_regulation of Pitx2 1 0.19 0.91 0.09 89.20
187 INT143838 Gene_expression of Pitx2 3 0.53 1.86 0.09 89.20
188 INT27527 Negative_regulation of Hal 2 0.42 0.66 0.42 89.12
189 INT200132 Regulation of Ercc2 2 0.36 4.56 0.05 89.08
190 INT200135 Regulation of Ercc3 2 0.34 3.47 0.05 89.08
191 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 88.96
192 INT71418 Binding of CES1 42 0.40 29.78 5.01 88.96
193 INT1169 Negative_regulation of Bche 322 0.59 149.22 61.27 88.88
194 INT56266 Gene_expression of F8a1 2 0.03 0.69 0.35 88.80
195 INT158409 Gene_expression of T2DM 3 0.65 9.58 0.56 88.80
196 INT7366 Negative_regulation of Ghrh 42 0.58 7.72 14.45 88.68
197 INT121834 Gene_expression of IAPP 24 0.66 20.96 0.26 88.60
198 INT112883 Gene_expression of Hspg2 22 0.65 6.54 4.95 88.52
199 INT80036 Positive_regulation of FAS 42 0.67 42.22 9.4 88.48
200 INT17417 Positive_regulation of Ighd 16 0.69 24.29 2.8 88.40
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