D:Leukoaraiosis

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pChart

Disease Term
Synonyms Leukoaraioses
Documents 23
Hot Single Events 4
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Leukoaraiosis. They are ordered first by their relevance to Leukoaraiosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT311727 Plat Regulation of Protein_catabolism of Col17a1 1 0.31 0.71 0.13 5.00
2 INT311731 Plat Regulation of Protein_catabolism of Pik3cd 1 0.31 0.71 0.13 5.00
3 INT311733 Plat Regulation of Protein_catabolism of Orai1 1 0.28 0.71 0.13 5.00
4 INT311737 Plat Regulation of Positive_regulation of Fcgr2b 1 0.31 0.71 0.13 5.00
5 INT311725 Binding of Plat and Mmp9 1 0.36 0.64 0.1 5.00
6 INT311734 Binding of Plat and Slpi 1 0.20 0.64 0.1 5.00
7 INT311735 Binding of Plat and Fcgr2b 1 0.29 0.65 0.1 5.00
8 INT311738 Binding of Anxa1 and Plat 1 0.19 0.63 0.1 5.00
9 INT311739 Binding of SELL and Plat 1 0.41 0.63 0.1 5.00
10 INT311726 Plat Positive_regulation of Gene_expression of Sele 1 0.09 0.6 0.04 5.00
11 INT311729 Plat Positive_regulation of Positive_regulation of Mmp9 1 0.34 0.71 0.04 5.00
12 INT311730 Binding of Plat and Lrp1 1 0.14 0.65 0.04 5.00
13 INT311724 Plat Positive_regulation of Gene_expression of Selp 1 0.11 0.6 0.03 5.00
14 INT311732 Plat Positive_regulation of Gene_expression of Esam 1 0.07 0.59 0.03 5.00
15 INT311736 Plat Positive_regulation of Gene_expression of Icam2 1 0.35 0.6 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Leukoaraiosis. They are ordered first by their pain relevance and then by number of times they were reported in Leukoaraiosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 98.76
2 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 92.88
3 INT104284 Positive_regulation of Notch3 7 0.50 5.57 0.99 83.72
4 INT180497 Binding of MRI1 45 0.42 28.35 14.77 82.88
5 INT107611 Regulation of Notch3 2 0.42 0.89 0.23 75.00
6 INT146421 Binding of Notch3 2 0.35 1.94 0.17 44.08
7 INT10513 Gene_expression of Plat 44 0.76 19.49 7.17 43.36
8 INT25445 Binding of Plat 7 0.41 12.75 1.63 35.80
9 INT258434 Gene_expression of Acadm 1 0.06 0.46 0.04 13.68
10 INT258435 Binding of Serpinb1c 3 0.24 2.43 0.07 6.20
11 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 5.00
12 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 5.00
13 INT47939 Gene_expression of Selp 171 0.76 87.54 39.03 5.00
14 INT68975 Gene_expression of Mmp9 111 0.78 79.57 38.55 5.00
15 INT68973 Positive_regulation of Mmp9 89 0.52 58.56 30.04 5.00
16 INT49487 Gene_expression of Sele 65 0.76 68.11 19.41 5.00
17 INT125247 Negative_regulation of Mmp9 42 0.43 23.68 9.37 5.00
18 INT17262 Negative_regulation of Plat 17 0.59 15.14 6.36 5.00
19 INT152293 Regulation of Mmp9 9 0.49 6.57 6.01 5.00
20 INT3550 Negative_regulation of GLA 52 0.59 33.93 5.26 5.00
21 INT125896 Negative_regulation of Gene_expression of Mmp9 15 0.43 13.73 4.18 5.00
22 INT4012 Negative_regulation of Psd 23 0.52 14.12 3.81 5.00
23 INT68974 Localization of Mmp9 10 0.80 4.84 3.35 5.00
24 INT27207 Gene_expression of Psd 31 0.73 15.44 2.75 5.00
25 INT10512 Positive_regulation of Gene_expression of Plat 8 0.46 1.4 2.69 5.00
26 INT9374 Regulation of Plat 19 0.61 6.04 2.55 5.00
27 INT10514 Negative_regulation of Gene_expression of Plat 8 0.47 6.22 2.24 5.00
28 INT102158 Protein_catabolism of Mmp9 7 0.65 5.43 1.91 5.00
29 INT48269 Negative_regulation of FANCB 16 0.56 5.34 1.38 5.00
30 INT97216 Positive_regulation of Psd 13 0.45 7.04 1.25 5.00
31 INT15896 Gene_expression of FANCB 18 0.65 6.44 1.18 5.00
32 INT116206 Transcription of Plat 3 0.67 1.52 1.18 5.00
33 INT167182 Binding of Psd 9 0.41 13.08 1.06 5.00
34 INT161766 Localization of Psd 7 0.75 3.53 0.96 5.00
35 INT263047 Transcription of Mmp9 7 0.53 3.61 0.65 5.00
36 INT272256 Protein_catabolism of Psd 3 0.49 2.66 0.19 5.00
37 INT259536 Transcription of Psd 2 0.38 1.25 0.16 5.00
38 INT115522 Regulation of Itgb2 3 0.19 0.5 0.15 5.00
39 INT311707 Positive_regulation of Protein_catabolism of Pik3cd 1 0.30 0.69 0.13 5.00
40 INT311708 Positive_regulation of Protein_catabolism of Col17a1 1 0.30 0.69 0.13 5.00
41 INT311710 Protein_catabolism of Orai1 1 0.48 0.63 0.13 5.00
42 INT311714 Protein_catabolism of Pik3cd 1 0.54 0.63 0.13 5.00
43 INT311723 Positive_regulation of Protein_catabolism of Orai1 1 0.27 0.69 0.13 5.00
44 INT311718 Positive_regulation of Fcgr2b 1 0.30 0.68 0.12 5.00
45 INT311721 Protein_catabolism of Col17a1 1 0.53 0.63 0.12 5.00
46 INT311715 Negative_regulation of Regulation of Plat 1 0.42 0.62 0.11 5.00
47 INT311720 Protein_catabolism of Plat 1 0.98 0.62 0.11 5.00
48 INT180693 Regulation of Timp3 2 0.22 0.4 0.05 5.00
49 INT311713 Regulation of Gene_expression of Plat 1 0.39 0.48 0.03 5.00
50 INT311717 Gene_expression of Esam 1 0.11 0.59 0.03 5.00
51 INT311722 Gene_expression of Icam2 1 0.54 0.59 0.03 5.00
52 INT272956 Positive_regulation of Binding of Psd 1 0.28 2.66 0 5.00
53 INT306111 Negative_regulation of NDUFA12 1 0.01 1.28 0 5.00
54 INT306112 Regulation of NDUFV1 1 0.02 1 0 5.00
55 INT311712 Regulation of Csf1 1 0.07 0.35 0 5.00
56 INT311716 Regulation of Serpinb6 1 0.17 0.45 0 5.00
57 INT311719 Regulation of Col17a1 1 0.16 0.33 0 5.00
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