D:Nephrotoxicity

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pChart

Disease Term
Synonyms Drug Induced Nephrotoxicity
Documents 692
Hot Single Events 200
Hot Interactions 6

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nephrotoxicity. They are ordered first by their relevance to Nephrotoxicity and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT124099 Binding of GGT5 and RYBP 1 0.00 0.34 1.26 100.00
2 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26 100.00
3 INT333396 CFD Positive_regulation of Bcl2l1 1 0.05 0.98 0.13 96.20
4 INT84466 DPP4 Regulation of Localization of Naga 1 0.00 0.87 0.78 96.04
5 INT333393 CFD Positive_regulation of Gene_expression of Timp1 1 0.07 0.82 0.16 92.60
6 INT283061 Binding of ERCC8 and LDLR 1 0.00 0.44 0 87.28
7 INT76865 Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2 78.56
8 INT76866 Negative_regulation of Lmo4 Positive_regulation of Sds 1 0.02 0.38 0.2 78.56
9 INT262288 CC2D1A Regulation of PPIG 1 0.00 1.39 0 77.52
10 INT53751 Positive_regulation of Cyp2e1 Positive_regulation of RYBP 1 0.14 0.89 1.98 75.00
11 INT53750 Cyp2e1 Positive_regulation of RYBP 1 0.14 0.44 0.99 75.00
12 INT47166 Binding of Asap1 and RYBP 1 0.02 0.15 0.41 75.00
13 INT146469 Otc Regulation of Cp 1 0.10 0.23 0 75.00
14 INT47165 Asap1 Regulation of Binding of Asap1 and Pah 1 0.29 0.07 0.17 75.00
15 INT47164 Binding of Asap1 and Pah 1 0.27 0.07 0.17 75.00
16 INT44977 Negative_regulation of Mthfs Negative_regulation of Gfra1 1 0.00 0.2 0.15 75.00
17 INT44978 Gfra1 Negative_regulation of Tbxa2r 1 0.00 0.44 0.12 75.00
18 INT44976 Avp Positive_regulation of Gene_expression of Ptger2 1 0.00 0.42 0.12 75.00
19 INT44974 Agt Positive_regulation of Gene_expression of Ptger2 1 0.02 0.42 0.12 75.00
20 INT52076 Binding of RYBP and Abt1 1 0.01 0.28 1.08 65.56
21 INT308816 Gpt Positive_regulation of Tnf 1 0.08 0.72 0.24 55.64
22 INT308815 Got1 Positive_regulation of Ldha 1 0.09 0.71 0.24 55.20
23 INT308818 Got1 Positive_regulation of Tnf 1 0.08 0.71 0.24 55.20
24 INT308817 Ldha Positive_regulation of Tnf 1 0.06 0.71 0.24 54.84
25 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 34.60
26 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 33.84
27 INT277811 Binding of CD28 and DCPS 1 0.04 0.05 0 32.92
28 INT337692 Cyp2b2 Positive_regulation of Nr1i3 1 0.00 0.31 0.05 27.32
29 INT337693 Cyp3a62 Positive_regulation of Nr1i3 1 0.01 0.31 0.05 26.92
30 INT175329 Binding of ICAM1 and ITGAL 14 0.18 10.06 2.81 20.24
31 INT277828 Negative_regulation of Binding of ICAM1 and ITGAL 2 0.22 1.27 0.57 20.24
32 INT277809 Binding of CD4 and CD40LG 1 0.15 0 0 20.12
33 INT189488 Binding of Ccr1 and Ccl5 8 0.40 9.26 3.27 16.96
34 INT222185 Binding of Ccr1 and Ccl3 4 0.23 2.7 1.47 16.96
35 INT297307 Negative_regulation of Binding of Ccr1 and Ccl3 1 0.27 0.73 0.67 16.96
36 INT297313 Negative_regulation of Binding of Ccr1 and Ccl5 1 0.28 0.74 0.67 16.96
37 INT233304 Binding of SRY and SLC22A8 1 0.34 0.93 0 16.64
38 INT349077 Binding of HLA-E and KLRD1 1 0.00 0.16 0 12.28
39 INT205120 Binding of CD4 and CD8A 3 0.15 2.83 0.72 8.56
40 INT293353 Binding of CD8A and Cd3e 1 0.01 0.07 0.04 8.56
41 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
42 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 5.00
43 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
44 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
45 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
46 INT239037 Binding of Cd28 and Cd86 9 0.16 3.69 2.14 5.00
47 INT241750 Binding of CD4 and ITIH4 14 0.18 5.72 1.53 5.00
48 INT265213 Binding of Ctla4 and Cd86 2 0.13 1.93 1.31 5.00
49 INT202620 Binding of Ppara and Rxra 15 0.09 2.63 1.11 5.00
50 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
51 INT265210 Binding of Ctla4 and Cd28 2 0.16 1.45 0.93 5.00
52 INT226340 Binding of CD4 and IFNA1 3 0.03 3.84 0.85 5.00
53 INT183698 Binding of Cxcr2 and Cxcl1 3 0.33 3.26 0.76 5.00
54 INT186123 Binding of GIF and IL10 1 0.23 1.17 0.69 5.00
55 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57 5.00
56 INT297311 Casp1 Positive_regulation of Il18 1 0.09 1.02 0.55 5.00
57 INT211993 Binding of Ppara and Rorb 1 0.00 1.13 0.54 5.00
58 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 5.00
59 INT291018 Binding of NSF and USE1 1 0.03 0.98 0.46 5.00
60 INT297316 Negative_regulation of Rock2 Positive_regulation of Cdh1 1 0.01 1.92 0.43 5.00
61 INT173977 Binding of TNF and Ighg1 1 0.03 0.28 0.39 5.00
62 INT155009 IL23A Positive_regulation of Gene_expression of IL17A 2 0.17 0.62 0.39 5.00
63 INT297314 Binding of Bsg and Sele 1 0.11 1.37 0.37 5.00
64 INT194641 Binding of IL10 and TNF 2 0.14 1.09 0.35 5.00
65 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 5.00
66 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 5.00
67 INT186127 CTLA4 Negative_regulation of CD28 1 0.19 0.74 0.32 5.00
68 INT333398 CFD Negative_regulation of Gene_expression of Pdgfa 1 0.02 0.64 0.3 5.00
69 INT211997 CORD1 Positive_regulation of Rara 1 0.01 0.68 0.29 5.00
70 INT321917 1200011M11Rik Positive_regulation of DAO 1 0.01 0.9 0.27 5.00
71 INT291019 Negative_regulation of Binding of NSF and USE1 1 0.03 0.59 0.26 5.00
72 INT325312 IL20 Positive_regulation of Phosphorylation of STAT3 1 0.13 0.58 0.24 5.00
73 INT325316 IL22 Positive_regulation of Phosphorylation of STAT3 1 0.19 0.58 0.24 5.00
74 INT325315 Binding of STAT3 and TH1L 1 0.16 0.6 0.23 5.00
75 INT325313 IL23A Positive_regulation of Gene_expression of IL22 1 0.20 0.48 0.23 5.00
76 INT333394 CFD Negative_regulation of Gene_expression of Cat 1 0.03 0.79 0.22 5.00
77 INT354544 Avp Positive_regulation of ADCY1 1 0.24 2.23 0.22 5.00
78 INT325314 Binding of IL12A and STAT3 1 0.19 0.6 0.22 5.00
79 INT333397 CFD Negative_regulation of Gene_expression of Nos2 1 0.04 0.8 0.22 5.00
80 INT325317 Binding of IL12A and TH1L 1 0.18 0.59 0.22 5.00
81 INT241822 Binding of CD4 and HIVEP1 3 0.01 2.73 0.21 5.00
82 INT321893 Binding of DAO and GRIN3B 1 0.03 0 0.19 5.00
83 INT321915 Binding of DAO and Ddo 1 0.07 0 0.19 5.00
84 INT297310 Binding of Cxcl1 and Rbm39 1 0.01 0.98 0.19 5.00
85 INT321914 Negative_regulation of Binding of Ddo and GRIN3B 1 0.01 0 0.19 5.00
86 INT126944 Binding of PKD2 and Pkd1 2 0.08 2.09 0.19 5.00
87 INT323134 Binding of IL10 and IL12A 1 0.06 0.55 0.18 5.00
88 INT319173 TXN Positive_regulation of Gene_expression of SOD2 1 0.23 0.1 0.18 5.00
89 INT293361 Binding of CD80 and KLRD1 1 0.00 0.38 0.16 5.00
90 INT321919 Binding of DAO and Gopc 1 0.02 0 0.16 5.00
91 INT321918 Binding of Ddo and GRIN3B 1 0.01 0 0.16 5.00
92 INT293359 Binding of CD86 and KLRD1 1 0.00 0.38 0.16 5.00
93 INT308551 Binding of HP and VPS45 1 0.04 0.44 0.15 5.00
94 INT241772 AVP Positive_regulation of ADCY1 1 0.09 1.08 0.15 5.00
95 INT262289 Regulation of Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 5.00
96 INT262290 Binding of PPIG and CC2D1A 1 0.01 1.52 0.13 5.00
97 INT297312 Esr1 Positive_regulation of Scap 1 0.00 1.58 0.13 5.00
98 INT241777 Negative_regulation of Binding of AVP and TRGV9 1 0.10 0.75 0.13 5.00
99 INT321916 DAO Regulation of Dao 1 0.36 0.84 0.12 5.00
100 INT293312 CTLA4 Negative_regulation of Binding of CD28 and CD80 1 0.01 0.29 0.12 5.00
101 INT211996 Erbb3 Positive_regulation of Nrg1 2 0.03 0.67 0.11 5.00
102 INT241774 Binding of AVPR1A and TRGV9 1 0.02 0.48 0.09 5.00
103 INT297317 Positive_regulation of Mthfd1 Positive_regulation of Gene_expression of Il18 1 0.07 0.79 0.08 5.00
104 INT297309 Positive_regulation of Mthfd1 Positive_regulation of Gene_expression of Ifng 1 0.07 0.79 0.08 5.00
105 INT220697 Binding of CHRNE and DBP 1 0.02 1.15 0.08 5.00
106 INT277807 CD40LG Regulation of CD40 1 0.21 0.17 0.08 5.00
107 INT329265 Binding of Ptk2 and Wnt2 1 0.05 1.04 0.07 5.00
108 INT220698 Binding of CHRNE and SFTPA1 1 0.01 0.75 0.06 5.00
109 INT218009 AHR Positive_regulation of CYP27B1 1 0.16 0.06 0.05 5.00
110 INT293360 Binding of CSH1 and FKBP1A 1 0.00 0.14 0.05 5.00
111 INT233303 Binding of CD4 and SRY 1 0.07 0.34 0.05 5.00
112 INT218010 EE Positive_regulation of CYP27B1 1 0.05 0 0.04 5.00
113 INT218011 AHR Positive_regulation of Transcription of CYP27B1 1 0.16 0 0.04 5.00
114 INT285863 Positive_regulation of IL12A Regulation of TH1L 1 0.01 0.25 0.04 5.00
115 INT283226 Binding of ACE and CC2D1A 1 0.11 2.37 0.04 5.00
116 INT285864 IL12A Regulation of TH1L 1 0.00 0.25 0.04 5.00
117 INT174204 Binding of SYNE1 and IL19 1 0.06 0.47 0.03 5.00
118 INT293367 Binding of CABIN1 and Ppia 1 0.00 0.19 0.03 5.00
119 INT293358 Binding of FKBP1A and CABIN1 1 0.00 0.07 0.03 5.00
120 INT229098 Binding of TP53 and IER3 1 0.01 1.47 0.03 5.00
121 INT293368 Binding of CSH1 and Ppia 1 0.00 0.19 0.03 5.00
122 INT192678 PTEN Regulation of Dync1h1 1 0.02 0.5 0.03 5.00
123 INT354622 CTSB Regulation of PRDX5 1 0.00 0.38 0 5.00
124 INT241775 AVP Positive_regulation of Gene_expression of AQP2 1 0.08 0.17 0 5.00
125 INT293355 Binding of Fkbp1a and CABIN1 1 0.00 0.12 0 5.00
126 INT174203 Binding of NTSR1 and FMN1 1 0.01 0.06 0 5.00
127 INT349079 Binding of CD80 and Cd86 1 0.22 0 0 5.00
128 INT241779 AVP Positive_regulation of TRGV9 1 0.17 0.48 0 5.00
129 INT241769 AVP Regulation of Binding of AVPR1A 1 0.11 0.49 0 5.00
130 INT241771 Binding of AVP and AVPR1B 1 0.04 0.49 0 5.00
131 INT333395 Binding of CFD and Aes 1 0.03 0.24 0 5.00
132 INT293357 RORC Regulation of PPP2R4 1 0.00 0 0 5.00
133 INT293354 Binding of CSH1 and Fkbp1a 1 0.00 0.12 0 5.00
134 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 5.00
135 INT266837 Dmp1 Negative_regulation of Gene_expression of Fgf23 1 0.48 2.41 0 5.00
136 INT283062 ERCC8 Positive_regulation of CFH 1 0.02 1.88 0 5.00
137 INT266835 Pth Regulation of Slc34a3 1 0.19 0.07 0 5.00
138 INT275232 DUOX2 Positive_regulation of ROS1 1 0.10 0.33 0 5.00
139 INT293366 Binding of CABIN1 and Fkbp1a 1 0.00 0.05 0 5.00
140 INT218012 EE Positive_regulation of ESR1 1 0.03 0 0 5.00
141 INT174205 PPIG Positive_regulation of CPA1 1 0.01 0.33 0 5.00
142 INT204730 PKD1P2 Negative_regulation of Ldha 1 0.05 0.37 0 5.00
143 INT293362 CSH1 Negative_regulation of Gene_expression of IL2 1 0.01 0.12 0 5.00
144 INT273495 GBP4 Negative_regulation of IMPDH1 1 0.03 0.2 0 5.00
145 INT241768 Binding of AVP and AVPR1A 1 0.08 0.49 0 5.00
146 INT266836 Pth Regulation of Slc34a1 1 0.09 0.07 0 5.00
147 INT241770 AVP Regulation of Binding of TRGV9 1 0.11 0.49 0 5.00
148 INT266839 Fgf23 Negative_regulation of Slc34a1 1 0.21 0.88 0 5.00
149 INT277808 Binding of APCS and CD80 1 0.11 0.07 0 5.00
150 INT266834 Pth Negative_regulation of Positive_regulation of Grxcr1 1 0.04 0.51 0 5.00
151 INT266833 Phex Regulation of Gene_expression of Fgf23 1 0.23 0.46 0 5.00
152 INT241773 AVP Regulation of Binding of AVPR1B 1 0.05 0.49 0 5.00
153 INT266838 Fgf23 Regulation of Slc34a1 1 0.13 0.3 0 5.00
154 INT353129 Binding of CD4 and CXCR4 1 0.13 1.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nephrotoxicity. They are ordered first by their pain relevance and then by number of times they were reported in Nephrotoxicity. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT18883 Negative_regulation of RYBP 53 0.56 21.14 57.52 100.00
2 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 100.00
3 INT266972 Positive_regulation of Atn1 1 0.12 0.88 0.28 100.00
4 INT89583 Protein_catabolism of Asap1 3 0.55 1.16 1.09 100.00
5 INT234 Binding of Alb 151 0.48 52.34 32.97 99.98
6 INT22967 Positive_regulation of RYBP 94 0.56 37.04 85.92 99.96
7 INT61190 Negative_regulation of Ggt1 4 0.42 2.4 2.24 99.92
8 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 99.88
9 INT103924 Positive_regulation of Akt1 359 0.69 158.94 60.34 99.88
10 INT262293 Gene_expression of CC2D1A 21 0.40 44.64 1.5 99.78
11 INT214883 Binding of Atcay 2 0.10 1.1 0.22 99.76
12 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 99.72
13 INT18881 Binding of Asap1 7 0.41 4.28 3.66 99.64
14 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 99.62
15 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 99.56
16 INT55597 Negative_regulation of Gpx1 59 0.55 28.3 8.83 99.50
17 INT52924 Negative_regulation of GSR 49 0.58 28.08 9.28 99.50
18 INT5279 Localization of Ggt1 9 0.81 2.8 1.99 99.40
19 INT91703 Negative_regulation of Myoz1 78 0.58 53.78 13.5 99.38
20 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 99.36
21 INT18884 Regulation of RYBP 25 0.38 11.43 23.2 99.24
22 INT52457 Gene_expression of ABCB1 129 0.78 38.68 19.88 99.20
23 INT64186 Positive_regulation of Gene_expression of TNFRSF11A 13 0.68 7.19 2.9 99.20
24 INT133858 Negative_regulation of BCS1L 13 0.51 8.65 0.2 99.14
25 INT11180 Binding of RYBP 52 0.46 13.86 42.53 99.00
26 INT308567 Binding of VPS45 1 0.32 2.48 0.08 99.00
27 INT14111 Positive_regulation of Cyp2c22 41 0.67 7.24 17.88 98.98
28 INT35406 Localization of Tnf 94 0.81 64.63 31.65 98.96
29 INT12097 Regulation of GGT1 8 0.44 5.76 1.95 98.88
30 INT61189 Regulation of Positive_regulation of Sord 1 0.18 0.33 1.04 98.88
31 INT12129 Gene_expression of CYP3A4 107 0.78 23.11 27.6 98.82
32 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56 98.82
33 INT64185 Gene_expression of TNFRSF11A 131 0.76 75.15 24.73 98.80
34 INT7673 Negative_regulation of ENG 31 0.42 7.9 8.61 98.80
35 INT1755 Gene_expression of GBE1 28 0.26 8.32 5.18 98.76
36 INT7180 Negative_regulation of Trib3 180 0.51 68.48 88.01 98.68
37 INT47859 Negative_regulation of Cyp2e1 41 0.59 16.92 21.72 98.66
38 INT8465 Regulation of Ptgs1 100 0.57 36.03 44.41 98.64
39 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 98.62
40 INT106023 Localization of PPIG 8 0.57 4.08 0.96 98.62
41 INT327446 Positive_regulation of Localization of PPIG 1 0.07 0.3 0.12 98.62
42 INT158796 Positive_regulation of SMUG1 67 0.70 38.97 8.98 98.56
43 INT12951 Negative_regulation of Cat 126 0.57 64.39 20.61 98.56
44 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9 98.36
45 INT35048 Localization of TNFSF14 5 0.68 3.12 0.66 97.96
46 INT207727 Positive_regulation of SRY 2 0.56 1.94 0.03 97.92
47 INT35895 Positive_regulation of Sord 8 0.69 3.25 4.45 97.88
48 INT18011 Positive_regulation of HP 60 0.50 31.88 4.75 97.86
49 INT49750 Negative_regulation of CPOX 735 0.58 360.06 274.19 97.76
50 INT60126 Regulation of Trpv1 186 0.62 85.53 133.4 97.72
51 INT266832 Positive_regulation of Grxcr1 9 0.12 7.91 0.19 97.68
52 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 97.64
53 INT9852 Positive_regulation of Gpt 563 0.70 364.64 146.82 97.60
54 INT374 Positive_regulation of Ldha 212 0.70 107.08 47.43 97.60
55 INT170854 Gene_expression of CFD 26 0.68 39.77 4.74 97.52
56 INT178237 Gene_expression of Vhl-ps1 15 0.43 8.56 0.54 97.44
57 INT35975 Regulation of Cpox 109 0.39 57.88 49.69 97.20
58 INT787 Localization of Ptgs1 31 0.80 12.36 11.55 97.20
59 INT61191 Negative_regulation of Clybl 1 0.08 0.32 0.96 97.12
60 INT22798 Regulation of Shbg 64 0.60 26.71 8.76 97.12
61 INT53748 Negative_regulation of Sord 2 0.24 1.12 1.22 97.04
62 INT266822 Negative_regulation of Grxcr1 10 0.10 8.12 0.17 97.04
63 INT266974 Protein_catabolism of AR 2 0.34 1.91 0.27 96.80
64 INT14510 Gene_expression of SOD1 208 0.76 88.56 12.4 96.76
65 INT31990 Positive_regulation of SOD1 124 0.69 67.79 12.52 96.76
66 INT96764 Positive_regulation of Gene_expression of SOD1 36 0.61 16.55 1.99 96.76
67 INT66673 Regulation of Pdia3 5 0.42 2.14 0.93 96.68
68 INT5254 Positive_regulation of Pla2g2a 22 0.68 10.42 6.37 96.64
69 INT17826 Positive_regulation of Pla2g1b 39 0.70 11.35 10.97 96.64
70 INT64648 Regulation of Selenbp2 4 0.23 1.63 2.05 96.40
71 INT52689 Regulation of Ptgs2 27 0.60 12.76 10.6 96.24
72 INT227519 Positive_regulation of Hspa9 22 0.55 16.38 3.83 96.24
73 INT84463 Regulation of Gene_expression of DPP4 5 0.39 4.81 1.33 96.04
74 INT36552 Regulation of Gene_expression of GGT1 2 0.44 1.29 0.87 96.04
75 INT84456 Regulation of Gene_expression of Naga 1 0.06 0.87 0.78 96.04
76 INT51377 Localization of Hexb 10 0.80 3.02 2.8 95.60
77 INT51378 Positive_regulation of Localization of Hexb 4 0.69 0.65 1.18 95.60
78 INT60970 Positive_regulation of Scr 9 0.59 12.21 1.03 95.40
79 INT138844 Positive_regulation of CC2D1A 25 0.41 41.36 1.92 95.36
80 INT120004 Transcription of Tp53 8 0.72 4.92 1.48 95.28
81 INT119271 Positive_regulation of BCS1L 13 0.50 7.56 0.39 95.28
82 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 95.16
83 INT28546 Regulation of SHBG 23 0.54 16.35 3.88 95.04
84 INT4656 Localization of RYBP 49 0.77 5.28 46.21 94.92
85 INT18882 Negative_regulation of Localization of RYBP 11 0.49 1.15 13.51 94.92
86 INT321907 Negative_regulation of DAO 1 0.51 9.08 7.07 94.92
87 INT205184 Positive_regulation of Positive_regulation of alp 2 0.11 1.25 0.16 94.92
88 INT83794 Positive_regulation of Gene_expression of Bcl2l1 26 0.69 16.89 4.28 94.84
89 INT83797 Gene_expression of Bcl2l1 124 0.77 94.55 22.39 94.84
90 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 94.76
91 INT20612 Positive_regulation of Asap1 36 0.68 24.35 6.06 94.72
92 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 94.72
93 INT24889 Negative_regulation of CABIN1 36 0.48 16.76 4.73 94.56
94 INT146793 Positive_regulation of Tp53 30 0.70 32.93 1.94 94.56
95 INT4679 Negative_regulation of RAPGEF5 55 0.57 47.51 4.55 94.44
96 INT58931 Binding of NAGLU 11 0.34 4.47 1.63 94.40
97 INT116146 Positive_regulation of Gene_expression of Tnfrsf21 1 0.15 1.03 0.79 94.32
98 INT29845 Positive_regulation of Sds 11 0.62 3.69 6.63 94.24
99 INT215353 Gene_expression of Tcf21 16 0.59 9.71 9.49 94.16
100 INT68396 Gene_expression of TRNAI1 3 0.34 7.79 0.85 94.16
101 INT6489 Positive_regulation of Gene_expression of Tnf 140 0.70 92.31 67.85 94.08
102 INT6486 Positive_regulation of Tnf 168 0.70 123.47 66.05 94.08
103 INT18779 Negative_regulation of Binding of RYBP 5 0.41 1.01 4.74 94.08
104 INT72834 Negative_regulation of Tcf21 10 0.58 5.8 4.84 94.00
105 INT76864 Negative_regulation of Positive_regulation of Sds 2 0.43 0.62 1.21 93.88
106 INT17961 Regulation of Pla2g4a 9 0.25 4.86 2.3 93.84
107 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 93.76
108 INT116145 Gene_expression of Tnfrsf21 2 0.27 1.68 0.93 93.76
109 INT10059 Binding of CSH1 17 0.35 5.28 3.37 93.72
110 INT52611 Negative_regulation of Ptgs2 142 0.59 66.31 52.71 93.68
111 INT154668 Gene_expression of Atn1 3 0.45 2.74 0.73 93.20
112 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 93.16
113 INT9854 Localization of GGT1 11 0.78 6.09 3.57 93.16
114 INT3755 Positive_regulation of GBE1 29 0.40 8.99 8.91 93.04
115 INT81604 Transcription of SLC22A6 2 0.63 0.67 0.78 93.00
116 INT64184 Negative_regulation of Gene_expression of TNFRSF11A 7 0.57 2.81 0.22 92.96
117 INT40844 Localization of Naga 2 0.53 2.88 3.42 92.84
118 INT84455 Gene_expression of Naga 2 0.43 1.11 0.77 92.84
119 INT291026 Gene_expression of NSF 1 0.53 4.05 0.91 92.64
120 INT84464 Gene_expression of DPP4 101 0.78 56.15 17.53 92.60
121 INT84465 Localization of DPP4 8 0.75 7.28 2.29 92.60
122 INT241787 Negative_regulation of AQP2 1 0.57 1.38 0.03 92.48
123 INT39747 Binding of Hhex 1 0.21 0.54 1.23 92.20
124 INT115773 Negative_regulation of Localization of Ptgs2 6 0.43 2.99 3.81 92.08
125 INT159775 Negative_regulation of Gene_expression of Timp1 9 0.37 4.36 1.08 92.08
126 INT112962 Regulation of Positive_regulation of Ppara 17 0.45 10.63 2.58 92.04
127 INT192808 Negative_regulation of Localization of PTH 6 0.59 7.31 0.45 92.00
128 INT73309 Regulation of Negative_regulation of PTGS2 14 0.44 9.55 4.5 92.00
129 INT29844 Regulation of Lpo 3 0.42 0.77 1.94 91.92
130 INT1973 Positive_regulation of NAGLU 36 0.65 14.78 7 91.80
131 INT30918 Positive_regulation of Hexb 3 0.45 0.72 0.38 91.80
132 INT112530 Localization of Ptgs2 13 0.70 7.77 5.86 91.68
133 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 91.64
134 INT52072 Negative_regulation of Ces1c 6 0.31 1.37 2.13 91.48
135 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 91.44
136 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 91.44
137 INT2544 Localization of PTH 39 0.81 30.55 2.22 91.44
138 INT4395 Positive_regulation of CSH1 20 0.50 6.27 1.52 91.16
139 INT16349 Positive_regulation of alp 25 0.60 16.74 4.34 91.12
140 INT52747 Negative_regulation of Positive_regulation of alp 3 0.30 1.54 0.97 91.12
141 INT181922 Binding of RENBP 16 0.36 13.92 3.71 91.08
142 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 91.04
143 INT291905 Localization of ART1 1 0.01 0.27 0.38 91.00
144 INT55740 Gene_expression of Timp1 53 0.75 28.63 13.85 90.92
145 INT45275 Gene_expression of CSH1 39 0.62 9.39 5.85 90.80
146 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 90.80
147 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 90.80
148 INT192806 Binding of SSRP1 11 0.27 9.12 0.37 90.80
149 INT238515 Localization of BAG3 3 0.34 0.4 0.8 90.72
150 INT90830 Localization of SLC22A6 3 0.69 0.86 0.89 90.60
151 INT25334 Negative_regulation of Pla2g2a 16 0.56 9.01 4.23 90.16
152 INT11071 Positive_regulation of PPBP 43 0.68 26.85 13.43 90.04
153 INT654 Localization of REN 250 0.81 75.12 47.86 89.84
154 INT51163 Gene_expression of Gal 119 0.78 67.48 49.23 89.68
155 INT14152 Gene_expression of Slc17a5 46 0.61 20.01 15.9 89.60
156 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 89.60
157 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 89.60
158 INT135016 Positive_regulation of Gene_expression of Slc17a5 7 0.55 4.33 3.74 89.60
159 INT94784 Binding of ROS1 113 0.40 71.57 10.26 89.56
160 INT53747 Positive_regulation of Cyp2e1 34 0.70 29.03 13.39 89.28
161 INT162393 Gene_expression of SMUG1 58 0.75 38.78 7.7 89.28
162 INT29846 Negative_regulation of Lpo 3 0.55 1.94 0.78 89.12
163 INT89794 Positive_regulation of CDKN2A 58 0.67 50.18 5.38 89.12
164 INT91159 Negative_regulation of Ros1 35 0.44 26.12 5.97 88.96
165 INT101959 Regulation of Rorb 10 0.14 5.18 3.17 88.88
166 INT86384 Negative_regulation of Localization of EGFR 4 0.43 2.5 0.97 88.84
167 INT83796 Regulation of Gene_expression of Bcl2l1 10 0.61 7.85 4.05 88.60
168 INT124648 Regulation of Transcription of Bcl2l1 1 0.31 0.09 0 88.60
169 INT76924 Positive_regulation of Slc17a5 71 0.70 41.21 19.31 88.44
170 INT156383 Positive_regulation of Positive_regulation of Slc17a5 2 0.31 0.61 1.23 88.44
171 INT53201 Negative_regulation of gr 35 0.50 17.76 10.62 88.08
172 INT124649 Transcription of Bcl2l1 2 0.65 0.16 0 87.96
173 INT18774 Gene_expression of RYBP 67 0.65 47.66 37.59 87.92
174 INT20586 Regulation of Gfra1 20 0.51 9.43 3.41 87.88
175 INT31599 Negative_regulation of Mgst1 14 0.59 5.35 1.72 87.80
176 INT113 Positive_regulation of MBD2 33 0.49 6.76 7.49 87.80
177 INT53746 Regulation of Cyp2e1 11 0.62 3.82 9.52 87.76
178 INT6478 Negative_regulation of Binding of TNF 36 0.58 30.42 13.31 87.64
179 INT193019 Positive_regulation of Positive_regulation of SMUG1 6 0.39 4.7 0.83 87.56
180 INT39746 Binding of Rnf14 2 0.03 1.31 6.03 87.36
181 INT10585 Localization of NAGLU 53 0.80 23.32 12.75 87.16
182 INT10586 Localization of B2M 15 0.68 8.67 3.46 87.16
183 INT6481 Binding of TNF 624 0.48 510.2 214.82 87.12
184 INT46 Localization of Ren 233 0.81 46.15 62.44 87.04
185 INT481 Regulation of Localization of Ren 37 0.62 5.95 11.61 87.04
186 INT291025 Positive_regulation of NSF 1 0.34 1.5 0.56 87.00
187 INT1701 Localization of Neu1 11 0.69 6.36 4.18 86.96
188 INT23199 Binding of LDLR 22 0.47 17.08 1.16 86.96
189 INT350897 Negative_regulation of Binding of ABL1 1 0.18 1.19 0.04 86.80
190 INT275242 Gene_expression of TSR1 1 0.01 1.42 0 86.48
191 INT31340 Positive_regulation of Gene_expression of Got1 20 0.46 10.5 3.17 86.44
192 INT34592 Positive_regulation of Gene_expression of ALPP 51 0.67 20.62 5.68 86.44
193 INT72052 Gene_expression of GSTA2 3 0.54 0.82 0.29 86.24
194 INT58301 Positive_regulation of Mpo 87 0.70 80.19 23.99 86.24
195 INT111377 Positive_regulation of Ifih1 16 0.60 11.22 6.99 86.24
196 INT118291 Binding of TXK 19 0.10 11.77 1.94 86.20
197 INT65545 Localization of EGFR 35 0.79 20.8 1.88 86.20
198 INT239412 Binding of ABL1 8 0.28 5.39 0.18 86.20
199 INT12169 Gene_expression of Serpina3n 2 0.48 3.44 0.34 86.08
200 INT168503 Binding of FUS 5 0.29 5.12 0.12 86.08
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