D:Nodular Goiter

Disease Term Synonyms Goiters Nodular, Nodular Goiters Documents 35 Hot Single Events 14 Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Nodular Goiter. They are ordered first by their relevance to Nodular Goiter and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT116124	Binding of AFP and HCC	2	0.20	1.72	0.15	5.00
2	INT308432	Binding of PDE4A and Aip	1	0.05	3.1	0.05	5.00
3	INT308425	Binding of Pde2a and Aip	1	0.04	1.37	0	5.00
4	INT308426	Binding of Pde4a and Aip	1	0.02	0.89	0	5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Nodular Goiter. They are ordered first by their pain relevance and then by number of times they were reported in Nodular Goiter. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Overall Pain Relevance	Term Relevance
1	INT914	Positive_regulation of GH1	292	0.69	100.7	84.91	98.28
2	INT34741	Positive_regulation of Gene_expression of GH1	58	0.67	35.06	7.8	98.28
3	INT985	Negative_regulation of GH1	213	0.57	89.53	32.39	97.60
4	INT956	Negative_regulation of PRL	94	0.59	42.72	23.01	97.60
5	INT28951	Negative_regulation of IGF1	133	0.59	75.77	18.9	97.60
6	INT531	Gene_expression of GH1	376	0.75	193.45	46.24	97.44
7	INT36686	Regulation of Tg	7	0.19	3.12	0.45	96.84
8	INT101047	Localization of Epgn	2	0.23	1.41	0.1	94.96
9	INT703	Positive_regulation of Pth	177	0.70	127.09	27.26	91.56
10	INT253	Regulation of PRL	184	0.62	47.27	65.79	90.92
11	INT921	Regulation of GH1	172	0.60	52.88	51.04	90.92
12	INT11729	Regulation of IGF1	71	0.61	44.58	9.71	90.92
13	INT154706	Gene_expression of Tg	9	0.38	4.95	0.64	83.36
14	INT9682	Positive_regulation of IGF1	238	0.70	120.03	26.36	83.12
15	INT115423	Gene_expression of Men1	4	0.47	14.08	0.64	77.68
16	INT10194	Positive_regulation of IL6	702	0.70	600.62	183.38	76.56
17	INT101048	Negative_regulation of Epgn	1	0.14	1.06	0	75.00
18	INT70242	Localization of HCC	18	0.66	23.95	2.35	73.64
19	INT252	Localization of GH1	529	0.80	227.4	122.05	66.88
20	INT425	Localization of PRL	455	0.81	189.64	144.8	66.88
21	INT248	Positive_regulation of Localization of GH1	137	0.69	49.25	32.92	57.00
22	INT1912	Gene_expression of Calca	1152	0.78	453.25	739.84	56.88
23	INT1624	Gene_expression of Cea	212	0.76	180.44	34.21	56.88
24	INT915	Positive_regulation of PRL	342	0.70	141.96	104.31	53.96
25	INT2005	Positive_regulation of Gene_expression of PRL	55	0.70	21.4	13.44	53.96
26	INT1579	Gene_expression of PRL	279	0.78	119.2	55.41	53.56
27	INT205796	Transcription of ERVW-1	5	0.52	2.16	0.24	53.28
28	INT78281	Gene_expression of Krt7	28	0.70	26.77	0.97	52.92
29	INT27652	Gene_expression of TG	36	0.78	22.36	2.74	40.40
30	INT186520	Gene_expression of CHKA	8	0.56	8.22	1	38.64
31	INT111477	Gene_expression of KRT7	90	0.74	86.76	4.07	38.32
32	INT125627	Gene_expression of TTF1	11	0.78	12.68	0.78	37.76
33	INT15040	Gene_expression of NKX2-1	8	0.65	3.95	1.02	37.20
34	INT194253	Positive_regulation of FIG4	2	0.27	1.39	0.12	37.12
35	INT121496	Gene_expression of TERT	107	0.78	45.6	7.42	35.52
36	INT15459	Gene_expression of TRH	17	0.78	4.89	8.17	35.20
37	INT916	Regulation of Localization of PRL	92	0.62	22.98	38.13	34.92
38	INT255	Regulation of Localization of GH1	89	0.62	18.71	35.3	34.92
39	INT171666	Regulation of GOPC	117	0.39	40.41	15.47	30.24
40	INT178840	Regulation of Localization of GOPC	5	0.25	0.78	0.14	30.24
41	INT15610	Localization of GOPC	223	0.65	68.26	28.7	29.76
42	INT90091	Gene_expression of GOPC	967	0.67	366.22	103.6	29.00
43	INT9683	Binding of GH1	57	0.47	21.14	5.99	12.08
44	INT443	Localization of POMC	1020	0.81	284.52	443.17	5.00
45	INT9238	Gene_expression of IL6	1575	0.78	1135.66	424.22	5.00
46	INT1893	Localization of Gh	1041	0.79	340.23	256.58	5.00
47	INT3448	Positive_regulation of Gh	521	0.69	180.03	161.18	5.00
48	INT1878	Binding of HLA-B	440	0.48	321.16	127.36	5.00
49	INT397	Localization of SST	232	0.81	58.05	101.19	5.00
50	INT1498	Gene_expression of Gh	521	0.75	220.84	81.16	5.00
51	INT17401	Gene_expression of IGF1	475	0.78	232.18	62.07	5.00
52	INT249	Localization of GHRH	215	0.80	78.02	51.87	5.00
53	INT16364	Gene_expression of HLA-DRA	234	0.78	118.81	45.01	5.00
54	INT4216	Gene_expression of CD40LG	328	0.78	256.02	44.23	5.00
55	INT157666	Positive_regulation of GOPC	335	0.60	120.19	42.75	5.00
56	INT5454	Localization of CRH	124	0.79	79.18	41.53	5.00
57	INT957	Positive_regulation of GHRH	136	0.70	36.84	40.52	5.00
58	INT918	Positive_regulation of Localization of PRL	90	0.70	23.97	40.3	5.00
59	INT7082	Gene_expression of CRH	180	0.78	64.66	31.74	5.00
60	INT6624	Gene_expression of Pth	135	0.76	110.27	27.54	5.00
61	INT16303	Negative_regulation of Localization of GH1	89	0.59	37.31	22.15	5.00
62	INT5328	Positive_regulation of CD4	191	0.69	133.43	21.31	5.00
63	INT955	Gene_expression of GHRH	126	0.78	59.91	20.74	5.00
64	INT1767	Positive_regulation of PROC	83	0.67	54.14	17	5.00
65	INT28950	Positive_regulation of Gene_expression of IGF1	99	0.69	46.9	16.47	5.00
66	INT170855	Negative_regulation of GOPC	188	0.38	70.92	15.41	5.00
67	INT9678	Positive_regulation of Positive_regulation of GH1	32	0.68	8.14	12.97	5.00
68	INT170601	Positive_regulation of Gene_expression of GOPC	122	0.43	42.79	11.68	5.00
69	INT34777	Localization of IGF1	82	0.80	42.68	8.62	5.00
70	INT6625	Negative_regulation of Pth	96	0.58	57.6	8.24	5.00
71	INT6511	Positive_regulation of AFP	76	0.70	70.15	7.28	5.00
72	INT17551	Positive_regulation of Gene_expression of HLA-DRA	31	0.70	15.39	6	5.00
73	INT121801	Binding of Aip	18	0.36	24.1	5.26	5.00
74	INT137178	Gene_expression of TLR3	46	0.72	24.97	4.33	5.00
75	INT148671	Gene_expression of Aip	26	0.63	24.32	3.91	5.00
76	INT84409	Binding of TNS1	6	0.48	2.96	3.33	5.00
77	INT1577	Negative_regulation of Gene_expression of PRL	24	0.59	7.7	3.15	5.00
78	INT8477	Negative_regulation of AFP	35	0.58	31.52	3.1	5.00
79	INT161382	Localization of KRT20	25	0.61	12.97	2.13	5.00
80	INT954	Positive_regulation of Gene_expression of GHRH	18	0.50	7.6	1.63	5.00
81	INT98096	Positive_regulation of CHKA	14	0.42	12.23	1.61	5.00
82	INT12370	Gene_expression of TNS1	6	0.67	1.7	1.37	5.00
83	INT114091	Negative_regulation of Aip	6	0.48	4.16	1.3	5.00
84	INT115982	Positive_regulation of KRT7	18	0.50	19.81	1.14	5.00
85	INT70021	Localization of BCL2	23	0.74	21.6	1.09	5.00
86	INT186807	Positive_regulation of Gene_expression of TLR3	8	0.53	7.19	1.08	5.00
87	INT45079	Binding of Ahr	21	0.44	10.07	1	5.00
88	INT219980	Positive_regulation of THRA	4	0.49	1.17	0.96	5.00
89	INT264171	Positive_regulation of Positive_regulation of CD4	5	0.49	4.74	0.94	5.00
90	INT153629	Negative_regulation of CHKA	3	0.12	2.33	0.92	5.00
91	INT184418	Negative_regulation of Positive_regulation of GOPC	15	0.26	5.47	0.87	5.00
92	INT180534	Gene_expression of SARS	40	0.59	35.47	0.81	5.00
93	INT186804	Binding of TLR3	14	0.45	8.41	0.79	5.00
94	INT154613	Regulation of Aip	5	0.21	3.86	0.55	5.00
95	INT45981	Negative_regulation of HRASLS	5	0.13	3.83	0.45	5.00
96	INT33518	Negative_regulation of Regulation of PRL	2	0.39	0.14	0.41	5.00
97	INT96186	Gene_expression of MLF1IP	5	0.53	8.54	0.41	5.00
98	INT194993	Binding of RB1	15	0.37	10.96	0.4	5.00
99	INT257213	Binding of PDE4A	5	0.36	1.69	0.3	5.00
100	INT219392	Positive_regulation of SLC5A8	1	0.41	2.4	0.23	5.00
101	INT219391	Positive_regulation of AIH3	1	0.13	1.26	0.23	5.00
102	INT263128	Negative_regulation of Binding of PDE4A	3	0.22	1.33	0.18	5.00
103	INT308431	Gene_expression of CNC	1	0.01	2.84	0.18	5.00
104	INT73080	Positive_regulation of TTF1	4	0.38	2.37	0.14	5.00
105	INT276149	Localization of SCG5	3	0.78	0.56	0.13	5.00
106	INT224235	Negative_regulation of Positive_regulation of CHKA	1	0.14	3.61	0.09	5.00
107	INT256822	Binding of Gm3813	2	0.36	1.81	0.08	5.00
108	INT219390	Negative_regulation of DIO1	1	0.19	0.39	0.08	5.00
109	INT268701	Negative_regulation of SLC25A5	2	0.31	2.61	0.08	5.00
110	INT264170	Binding of BIRC2	1	0.01	1.19	0.08	5.00
111	INT211806	Gene_expression of PLXNC1	4	0.63	2.95	0.07	5.00
112	INT89933	Negative_regulation of Tg	2	0.04	1.78	0.06	5.00
113	INT175895	Negative_regulation of KRT1	5	0.37	3.23	0.05	5.00
114	INT308430	Negative_regulation of PRKAR1A	1	0.11	0.83	0.04	5.00
115	INT308415	Negative_regulation of Transcription of Aip	1	0.48	0.82	0.03	5.00
116	INT308414	Negative_regulation of Gene_expression of Aip	1	0.48	0.82	0.03	5.00
117	INT276148	Negative_regulation of Positive_regulation of SLC25A5	1	0.08	0.68	0.03	5.00
118	INT276150	Positive_regulation of SLC25A5	1	0.13	0.68	0.03	5.00
119	INT308416	Regulation of Gene_expression of Aip	1	0.37	0.77	0	5.00
120	INT308427	Positive_regulation of MTUS1	1	0.00	1.02	0	5.00
121	INT308417	Transcription of Aip	1	0.59	0.82	0	5.00