D:Ocular Hypertension

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pChart

Disease Term
Synonyms Glaucoma Ocular Hypertension, Glaucoma Suspect, GLAUCOMAS SUSPECT, Hypertension Ocular, Hypertensions Ocular, Intra Ocular Hypertension, Intra Ocular Pressure, INTRAOCULAR HYPERTENSION, Intraocular Pressure, Ocular Hypertensions, SUSPECT GLAUCOMA
Documents 1167
Hot Single Events 200
Hot Interactions 41

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Ocular Hypertension. They are ordered first by their relevance to Ocular Hypertension and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT170561 Renbp Regulation of Narf 1 0.01 3.86 0 100.00
2 INT170558 Binding of Myoc and Narf 1 0.04 3.03 0.63 100.00
3 INT247855 Positive_regulation of Narfl Regulation of Aqp4 1 0.04 2.93 0.04 100.00
4 INT273772 BCKDHA Positive_regulation of Positive_regulation of NARFL 1 0.03 1.21 0 100.00
5 INT247850 Positive_regulation of Narfl Regulation of Ube4a 1 0.00 1.86 0 100.00
6 INT247856 Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 1 0.03 100.00
7 INT170562 Car2 Regulation of Narf 1 0.05 1.17 0 100.00
8 INT170559 Narf Regulation of Gene_expression of Car2 1 0.05 1.01 0 100.00
9 INT170560 Binding of Renbp and Narf 1 0.01 1.69 0.27 100.00
10 INT247843 Narfl Regulation of Aqp4 1 0.04 1.07 0.04 100.00
11 INT247889 Positive_regulation of Narfl Positive_regulation of CASP3 1 0.00 0.84 0 100.00
12 INT247852 Narfl Positive_regulation of Localization of Aqp4 1 0.08 0.81 0 100.00
13 INT247857 Narfl Positive_regulation of Gene_expression of Gfap 1 0.07 0.81 0 100.00
14 INT247888 Narfl Positive_regulation of CASP3 1 0.00 0.77 0 100.00
15 INT247847 Narfl Positive_regulation of Positive_regulation of Casp3 1 0.02 0.79 0 100.00
16 INT247846 Positive_regulation of Narfl Positive_regulation of Positive_regulation of Ube4a 1 0.00 0.82 0 100.00
17 INT247851 Negative_regulation of Aqp4 Negative_regulation of Positive_regulation of Narfl 1 0.09 1.78 0.15 100.00
18 INT247853 Positive_regulation of Narfl Negative_regulation of Gene_expression of Uchl1 1 0.03 0.54 0 100.00
19 INT247848 Narfl Negative_regulation of Uchl1 1 0.03 0.74 0 100.00
20 INT289981 Cntf Negative_regulation of Casp3 1 0.02 1.01 0.22 100.00
21 INT289998 CNTF Negative_regulation of Casp3 1 0.04 0.99 0.22 100.00
22 INT289997 CNTF Negative_regulation of Binding of CNTF and Casp3 1 0.05 0.99 0.22 100.00
23 INT289999 Binding of CNTF and Casp3 1 0.04 0.99 0.22 100.00
24 INT169604 Nppb Positive_regulation of Npr1 2 0.52 2.52 0.37 99.04
25 INT299233 Onc1 Regulation of Gene_expression of Aqp9 1 0.01 0.19 0 97.32
26 INT344238 MCRS1 Regulation of TREX1 1 0.08 1.02 0.34 96.20
27 INT272143 PTAFR Positive_regulation of Gene_expression of PTGS2 1 0.12 1.59 0.23 94.20
28 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 94.08
29 INT247849 Edn1 Regulation of Gene_expression of Aqp4 1 0.12 1.05 0 93.64
30 INT294413 Proc Positive_regulation of Cdc42ep3 1 0.00 0.78 0 91.84
31 INT302511 Binding of OPA1 and Nos3 1 0.02 1.57 0.1 89.84
32 INT302507 Binding of GLC1F and OPA1 1 0.01 3.76 0 89.68
33 INT209581 Twist1 Positive_regulation of Gene_expression of VEGFA 6 0.06 7.86 0.16 88.72
34 INT285022 Regulation of Bak1 Regulation of Bcl2 1 0.09 0.71 0.17 88.40
35 INT285026 Bak1 Regulation of Bcl2 1 0.09 0.71 0.17 88.40
36 INT285024 Bcl2 Regulation of Bak1 1 0.09 0.71 0.17 88.40
37 INT285077 CCL16 Positive_regulation of ITK 1 0.05 1.95 0.31 87.68
38 INT285076 CCL16 Positive_regulation of Gene_expression of ITK 1 0.05 1.8 0.14 87.68
39 INT267116 Binding of Lmx1b and Nps 1 0.30 1.95 0 83.12
40 INT353109 Binding of VEGFA and Aes 1 0.02 3.93 0.43 82.24
41 INT275667 Binding of CYP1B1 and GLC3C 1 0.27 0.99 0 80.20
42 INT278441 Lbp Positive_regulation of Gene_expression of ITGAX 1 0.44 1.18 0.07 79.20
43 INT249332 GPNMB Positive_regulation of EGFR 1 0.17 2.63 0.08 75.36
44 INT249324 GPNMB Positive_regulation of GPNMB Positive_regulation of EGFR 1 0.12 1.31 0.04 74.88
45 INT355408 Ins1 Regulation of Dbi 1 0.07 0.58 0.14 73.32
46 INT300449 VEGFA Positive_regulation of Protein_catabolism of Ppp2r2b 1 0.00 1.51 0.05 71.84
47 INT111080 Binding of CA1 and CA2 2 0.02 1.62 0.73 71.40
48 INT259716 Loxl1 Regulation of Loxl1 1 0.00 1.84 0.08 71.40
49 INT301054 Tfap2a Regulation of Gene_expression of Faslg 1 0.00 1.23 0.34 68.96
50 INT255660 Coq10a Negative_regulation of Rgc32 1 0.02 1.11 0.13 63.20
51 INT262820 Binding of Aif1 and Serpinf1 1 0.01 1.3 0.27 61.92
52 INT280569 Binding of GEM and HIVEP1 1 0.00 1.59 0.03 60.52
53 INT280601 Binding of HIVEP1 and Dbi 1 0.00 1.57 0.03 59.28
54 INT263584 Hspa5 Positive_regulation of Myo1b 1 0.00 1.02 0 58.76
55 INT263586 Hspa5 Positive_regulation of Esr1 1 0.15 1.01 0 58.76
56 INT272528 THBS1 Positive_regulation of TGFB2 1 0.09 0.64 0.03 58.32
57 INT347577 Binding of MUC1 and MUC16 1 0.25 0.42 0 56.64
58 INT263585 Binding of Phlda2 and Gmcl1 1 0.02 0.59 0 53.76
59 INT255658 Coq10a Regulation of Negative_regulation of Rgc32 1 0.01 1.14 0.14 50.40
60 INT278438 Lbp Positive_regulation of Il2 1 0.12 0.89 0 50.00
61 INT262826 Serpinf1 Negative_regulation of Gene_expression of TNF 1 0.29 1.83 0.28 49.00
62 INT285068 ITK Regulation of CCL16 1 0.02 1.86 0.03 46.32
63 INT285067 Negative_regulation of ITK Regulation of CCL16 1 0.04 1.1 0.03 46.32
64 INT267118 Lmx1b Regulation of Regulation of Col7a1 1 0.06 0.47 0 45.84
65 INT285023 Casp3 Negative_regulation of Casp7 1 0.07 0.44 0.1 45.28
66 INT262825 Serpinf1 Negative_regulation of Gfap 1 0.34 0.87 0.08 44.32
67 INT227774 Negative_regulation of Binding of Cd40 and Cd40lg 1 0.31 0.29 0.03 42.76
68 INT262821 Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.54 0.85 0.08 42.40
69 INT188692 Binding of Cd40 and Cd40lg 32 0.34 22.95 6.62 42.12
70 INT355410 Ins1 Regulation of Gene_expression of Dbi 1 0.07 0.57 0.16 41.60
71 INT261981 EP400 Negative_regulation of CYP1B1 1 0.01 0.22 0 39.68
72 INT262822 Serpinf1 Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.07 1.27 0.18 38.24
73 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 37.00
74 INT267119 Lmx1b Regulation of Regulation of Col4a1 1 0.09 0.67 0 36.28
75 INT209580 Twist1 Positive_regulation of Localization of VEGFA 1 0.05 0.53 0 34.04
76 INT235800 Twist1 Positive_regulation of VEGFA 1 0.02 0.62 0.03 32.52
77 INT285025 Bnip3 Positive_regulation of Bak1 1 0.11 0.78 0.07 27.52
78 INT285032 Bnip3 Positive_regulation of Bax 1 0.28 0.77 0.07 26.88
79 INT222811 Binding of Hand2 and TH1L 4 0.03 8.26 0.69 24.84
80 INT262817 Serpinf1 Regulation of Positive_regulation of 1190002H23Rik 1 0.06 1.3 0.22 22.72
81 INT300445 VEGFA Positive_regulation of Vegfa 1 0.03 1.33 0.03 22.24
82 INT300446 VEGFA Positive_regulation of Flt1 1 0.09 2.62 0.07 19.36
83 INT262824 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Il18 1 0.39 1.56 0.37 16.72
84 INT267115 Lmx1b Regulation of Gene_expression of Col4a1 1 0.09 1.37 0 16.40
85 INT337916 sb Negative_regulation of Ctgf 1 0.00 0.13 0 12.96
86 INT337917 Binding of sb and Tgfbr1 1 0.00 1.06 0 12.64
87 INT337914 sb Negative_regulation of Phosphorylation of Smad2 1 0.00 0.13 0 12.24
88 INT294412 Binding of Vav2 and Vav3 1 0.41 0.65 0 11.60
89 INT262815 Gene_expression of Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.39 2.73 0.44 10.80
90 INT262819 Gene_expression of Serpinf1 Negative_regulation of Binding of 1190002H23Rik 1 0.05 2.66 0.43 10.80
91 INT267117 Lmx1b Regulation of Col7a1 1 0.02 1.29 0 7.36
92 INT127128 Binding of CNR1 and CNR2 8 0.39 3.98 3.97 5.00
93 INT24388 CRH Positive_regulation of Localization of POMC 8 0.51 5.67 3.35 5.00
94 INT134212 CRH Regulation of Localization of POMC 1 0.47 2.89 2.9 5.00
95 INT249013 Gabrg1 Negative_regulation of Per2 1 0.34 0.07 2.31 5.00
96 INT249005 Gabrg1 Positive_regulation of Per2 1 0.39 0 1.7 5.00
97 INT101926 Binding of Dio1 and Drd2 4 0.28 0.39 1.66 5.00
98 INT249014 Gabrg1 Regulation of Per2 1 0.31 0 1.24 5.00
99 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16 5.00
100 INT249002 Gabrg1 Positive_regulation of Protein_catabolism of Per1 1 0.35 0.09 1.15 5.00
101 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
102 INT285418 IRF6 Positive_regulation of Localization of IL6 3 0.05 0.66 0.93 5.00
103 INT289461 IRF6 Positive_regulation of ICAM1 1 0.08 0.61 0.91 5.00
104 INT249012 Binding of Akt1 and Gabrg1 1 0.01 0 0.9 5.00
105 INT272144 PTAFR Positive_regulation of HRASLS 1 0.08 1.08 0.89 5.00
106 INT181616 INS Positive_regulation of IRS1 1 0.01 1 0.79 5.00
107 INT181615 SRC Positive_regulation of IRS1 1 0.01 0.98 0.77 5.00
108 INT249023 Gabrg1 Positive_regulation of Csn2 1 0.02 0 0.74 5.00
109 INT259556 PLEK Negative_regulation of Gene_expression of VEGFA 1 0.46 2.15 0.73 5.00
110 INT259557 PLEK Negative_regulation of Positive_regulation of VEGFA 1 0.46 2.15 0.73 5.00
111 INT272147 PTAFR Positive_regulation of CA2 1 0.13 0 0.71 5.00
112 INT248998 Gabrg1 Regulation of Luc7l3 1 0.05 0 0.69 5.00
113 INT249018 Gabrg1 Regulation of Localization of Per2 1 0.35 0 0.69 5.00
114 INT249010 Gabrg1 Regulation of Positive_regulation of Per1 1 0.33 0 0.67 5.00
115 INT249008 Gabrg1 Regulation of Per1 1 0.33 0 0.67 5.00
116 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
117 INT200808 Binding of Akt1 and Insrr 2 0.00 0.98 0.61 5.00
118 INT272146 PTAFR Positive_regulation of Localization of IL8 3 0.38 0.28 0.59 5.00
119 INT249027 Gabrg1 Negative_regulation of Luc7l3 1 0.05 0.07 0.59 5.00
120 INT249029 Binding of Csn2 and Insrr 1 0.00 0 0.59 5.00
121 INT248993 Binding of Csn2 and Ptar1 1 0.00 0 0.59 5.00
122 INT248994 Binding of Akt1 and Ptar1 1 0.00 0 0.58 5.00
123 INT181619 ACE Positive_regulation of KNG1 1 0.33 0.97 0.58 5.00
124 INT249009 Gabrg1 Regulation of Gene_expression of Per2 1 0.40 0 0.56 5.00
125 INT249022 Gabrg1 Regulation of Gene_expression of Luc7l3 1 0.07 0 0.56 5.00
126 INT249001 Gabrg1 Positive_regulation of Arntl 1 0.29 0 0.55 5.00
127 INT249006 Gabrg1 Positive_regulation of Transcription of Arntl 1 0.31 0 0.55 5.00
128 INT249024 Gabrg1 Positive_regulation of Transcription of Per1 1 0.59 0 0.55 5.00
129 INT249020 Gabrg1 Positive_regulation of Per1 1 0.40 0 0.55 5.00
130 INT248997 Gabrg1 Positive_regulation of Clock 1 0.37 0 0.54 5.00
131 INT248995 Gabrg1 Regulation of Transcription of Clock 1 0.36 0 0.54 5.00
132 INT249007 Gabrg1 Regulation of Transcription of Per2 1 0.35 0 0.54 5.00
133 INT249016 Gabrg1 Positive_regulation of Transcription of Clock 1 0.37 0 0.54 5.00
134 INT248996 Gabrg1 Negative_regulation of Gene_expression of Per2 1 0.33 0 0.51 5.00
135 INT249025 Gabrg1 Negative_regulation of Gene_expression of Luc7l3 1 0.07 0 0.51 5.00
136 INT249026 Gabrg1 Positive_regulation of Luc7l3 1 0.06 0 0.51 5.00
137 INT289464 Negative_regulation of IRF6 Positive_regulation of ICAM1 1 0.07 0.31 0.5 5.00
138 INT215543 Negative_regulation of Trim33 Negative_regulation of Gopc 1 0.15 0.35 0.48 5.00
139 INT289462 Negative_regulation of IRF6 Positive_regulation of IL1B 2 0.04 0.31 0.48 5.00
140 INT289463 IRF6 Positive_regulation of Localization of IL1B 1 0.05 0.52 0.48 5.00
141 INT249000 Helt Negative_regulation of Per2 1 0.01 0 0.48 5.00
142 INT292814 Binding of VEGFA and Kdr 8 0.18 3.63 0.48 5.00
143 INT102364 BRD1 Positive_regulation of Twist1 1 0.00 0 0.47 5.00
144 INT249021 Gabrg1 Negative_regulation of Th 1 0.08 0.06 0.44 5.00
145 INT114341 Agt Positive_regulation of AGT 3 0.01 1.15 0.43 5.00
146 INT249011 Gabrg1 Regulation of Clock 1 0.19 0 0.43 5.00
147 INT283714 Positive_regulation of Binding of Id2 and Homer1 1 0.08 1.34 0.42 5.00
148 INT283713 Binding of Id2 and Homer1 1 0.06 1.34 0.42 5.00
149 INT272148 PTAFR Regulation of Localization of CA2 1 0.14 0 0.38 5.00
150 INT249004 Helt Regulation of Clock 1 0.01 0.09 0.37 5.00
151 INT249015 Regulation of Helt Regulation of Clock 1 0.01 0.09 0.37 5.00
152 INT221814 Mastl Positive_regulation of Ppara 1 0.04 0.68 0.37 5.00
153 INT249019 Gabrg1 Positive_regulation of Akt1 1 0.02 0 0.34 5.00
154 INT241451 Mag Positive_regulation of Ngfr 1 0.09 0.1 0.21 5.00
155 INT272150 Positive_regulation of PTAFR Positive_regulation of HRASLS 1 0.06 0.16 0.21 5.00
156 INT181646 interleukin-17 Positive_regulation of ISYNA1 1 0.01 0.26 0.2 5.00
157 INT181617 IL17A Positive_regulation of ISYNA1 1 0.01 0.27 0.2 5.00
158 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 5.00
159 INT262818 Serpinf1 Negative_regulation of Gene_expression of Gfap 1 0.45 0.71 0.18 5.00
160 INT304964 Binding of AMT and PTK2B 1 0.23 0.78 0.18 5.00
161 INT241462 Binding of OMG and Ngfr 1 0.11 0.15 0.15 5.00
162 INT241457 Binding of Mag and Ngfr 1 0.09 0.15 0.15 5.00
163 INT241453 Binding of Ngfr and Rtn4r 1 0.03 0.15 0.15 5.00
164 INT314856 Binding of Cdc7 and Cdkn2a 1 0.28 1.34 0.14 5.00
165 INT241465 Binding of OMG and Rtn4r 1 0.04 0.15 0.14 5.00
166 INT314867 Binding of Cdc7 and Cdkn2b 1 0.25 1.16 0.14 5.00
167 INT314852 Binding of Cdkn2a and Tgfbr3 1 0.28 1.15 0.14 5.00
168 INT241458 Binding of Mag and Rtn4r 1 0.03 0.15 0.14 5.00
169 INT314859 Binding of Cdkn2b and Tgfbr3 1 0.33 1.16 0.14 5.00
170 INT239790 SLC12A5 Regulation of SLC12A2 1 0.11 0.08 0.13 5.00
171 INT241454 Rgnef Positive_regulation of Positive_regulation of Rhoa 1 0.04 0.11 0.13 5.00
172 INT272145 Binding of PTAFR and HRASLS 1 0.04 0.06 0.13 5.00
173 INT262618 Binding of SOAT1 and Kras 1 0.00 0.81 0.12 5.00
174 INT272149 PTAFR Positive_regulation of Localization of IL6 1 0.24 0 0.12 5.00
175 INT235775 Binding of Tnfrsf1a and Tradd 3 0.31 3 0.12 5.00
176 INT283719 Id2 Regulation of Regulation of Hes7 1 0.00 0.31 0.12 5.00
177 INT241446 Rgnef Positive_regulation of Rhoa 1 0.04 0.1 0.12 5.00
178 INT285030 Binding of Bax and Slc25a4 1 0.03 0.84 0.11 5.00
179 INT283710 Binding of Id2 and Hes7 1 0.01 0.13 0.11 5.00
180 INT223088 Binding of ELF3 and NAGLU 1 0.14 0.84 0.09 5.00
181 INT223089 Binding of IDS and NAGLU 1 0.26 0.72 0.09 5.00
182 INT285070 CCL16 Positive_regulation of Gene_expression of CYP19A1 1 0.02 0.69 0.09 5.00
183 INT342232 Binding of POR and SEPP1 1 0.02 0.75 0.08 5.00
184 INT342231 Binding of SEPP1 and ARC 1 0.04 3.84 0.08 5.00
185 INT283721 Binding of Lpin1 and Id2 1 0.38 0.18 0.08 5.00
186 INT342230 Binding of ARC and PKD1P4 1 0.01 5.72 0.07 5.00
187 INT181645 Edn1 Positive_regulation of NOS3 1 0.02 0.21 0.07 5.00
188 INT241444 Binding of Tnfrsf19 and Lingo1 1 0.08 0.49 0.06 5.00
189 INT241447 Binding of Tnfrsf19 and Rtn4r 1 0.04 0.49 0.06 5.00
190 INT241461 Binding of TNF and Tnfrsf19 1 0.17 0.49 0.06 5.00
191 INT251803 PTH1R Positive_regulation of PTH 1 0.08 0.06 0.05 5.00
192 INT353105 Binding of Aes and Rgs9bp 1 0.01 0.35 0.05 5.00
193 INT248999 Binding of Per2 and Luc7l3 1 0.05 0 0.05 5.00
194 INT310674 Positive_regulation of Binding of ARSB and ELF3 1 0.07 2.46 0.05 5.00
195 INT284705 CMA1 Positive_regulation of Gene_expression of COL7A1 1 0.04 0.49 0.05 5.00
196 INT310675 Binding of ARSB and ELF3 1 0.06 2.4 0.05 5.00
197 INT329015 Binding of APCS and SRGN 1 0.08 1.14 0.04 5.00
198 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04 5.00
199 INT255659 Binding of Anxa5 and Ca2 1 0.02 1.23 0.04 5.00
200 INT241449 Mag Positive_regulation of Protein_catabolism of Ngfr 1 0.09 0 0.03 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Ocular Hypertension. They are ordered first by their pain relevance and then by number of times they were reported in Ocular Hypertension. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 100.00
2 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 100.00
3 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 100.00
4 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 100.00
5 INT170547 Positive_regulation of Narf 29 0.06 64.48 1.61 100.00
6 INT266875 Positive_regulation of Narfl 37 0.05 38.43 3.73 100.00
7 INT170548 Regulation of Narf 1 0.06 34.17 2.18 100.00
8 INT247868 Positive_regulation of Narfl 1 0.11 37.11 0.68 100.00
9 INT272274 Localization of NARFL 24 0.60 27.55 1.18 100.00
10 INT272272 Positive_regulation of Gene_expression of NARFL 17 0.40 18.85 0.31 100.00
11 INT181642 Negative_regulation of Narf 2 0.01 28.07 4.01 100.00
12 INT39369 Binding of NARFL 14 0.29 16.7 0.93 100.00
13 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 100.00
14 INT170553 Negative_regulation of Narf 12 0.05 16.19 3.78 100.00
15 INT170556 Gene_expression of Narf 1 0.06 17.85 1.96 100.00
16 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 100.00
17 INT272414 Positive_regulation of Positive_regulation of NARFL 9 0.37 12.88 0.84 100.00
18 INT170550 Binding of Narf 9 0.04 14.89 1.18 100.00
19 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 100.00
20 INT247865 Gene_expression of Narfl 1 0.09 9.22 0.13 100.00
21 INT98624 Regulation of Aqp4 27 0.62 30.76 3.77 100.00
22 INT99965 Positive_regulation of Negative_regulation of NARFL 6 0.40 4.5 0.04 100.00
23 INT185649 Regulation of ERG 17 0.20 10.14 1.49 100.00
24 INT274273 Regulation of Gene_expression of NARFL 3 0.10 4.39 0.2 100.00
25 INT247867 Positive_regulation of Positive_regulation of Narfl 1 0.11 5.16 0.05 100.00
26 INT289498 Negative_regulation of Narfl 4 0.03 3.05 0.31 100.00
27 INT289988 Gene_expression of Narf 1 0.02 3.35 0.67 100.00
28 INT289496 Gene_expression of Narfl 3 0.05 3.43 0.25 100.00
29 INT170551 Positive_regulation of Positive_regulation of Narf 2 0.05 3.83 0 100.00
30 INT170549 Localization of Narf 1 0.07 2.67 0.38 100.00
31 INT108246 Regulation of Renbp 5 0.21 4.66 1.12 100.00
32 INT272530 Negative_regulation of Localization of NARFL 3 0.09 2.98 0.07 100.00
33 INT274271 Negative_regulation of Negative_regulation of NARFL 1 0.06 5.13 0.22 100.00
34 INT289497 Binding of Narfl 1 0.03 2.23 0 100.00
35 INT289492 Localization of Narfl 1 0.05 2.38 0 100.00
36 INT247866 Localization of Narfl 1 0.10 1.98 0.09 100.00
37 INT93777 Negative_regulation of Rgs2 3 0.43 2.5 2.81 100.00
38 INT27864 Regulation of Sysbp1 9 0.22 3.76 3.42 100.00
39 INT289989 Positive_regulation of Narf 1 0.02 3.85 0.73 100.00
40 INT289493 Regulation of Narfl 1 0.03 1.61 0 100.00
41 INT58816 Regulation of Regulation of NARFL 2 0.11 1.39 0.16 100.00
42 INT54810 Negative_regulation of Positive_regulation of TIMM13 1 0.22 1.89 0.07 100.00
43 INT54811 Negative_regulation of TIMM13 2 0.22 2.46 0.07 100.00
44 INT22549 Positive_regulation of Positive_regulation of Casp3 48 0.56 29.5 23.7 100.00
45 INT247873 Binding of Narfl 1 0.05 1.33 0.07 100.00
46 INT16357 Negative_regulation of NPPA 23 0.58 12.37 2.98 100.00
47 INT3776 Positive_regulation of Regulation of NARFL 2 0.37 2.44 0.93 100.00
48 INT49555 Positive_regulation of Positive_regulation of Gfap 18 0.69 11.51 10.29 100.00
49 INT170545 Regulation of Positive_regulation of Narf 1 0.04 1.44 0 100.00
50 INT247878 Negative_regulation of Positive_regulation of Narfl 1 0.06 2.14 0.03 100.00
51 INT274269 Transcription of NARFL 1 0.09 1.13 0.03 100.00
52 INT274274 Positive_regulation of Transcription of NARFL 1 0.06 1.13 0.03 100.00
53 INT40698 Positive_regulation of Aes 3 0.32 3.84 0.65 100.00
54 INT247876 Negative_regulation of Localization of Narfl 1 0.06 0.94 0 100.00
55 INT247869 Regulation of Positive_regulation of Narfl 1 0.06 1.85 0 100.00
56 INT170554 Binding of Renbp 17 0.17 12.36 0.45 100.00
57 INT247877 Negative_regulation of Gene_expression of Narfl 1 0.06 1.05 0 100.00
58 INT64858 Negative_regulation of Positive_regulation of sch 1 0.37 0.81 0.36 100.00
59 INT2924 Positive_regulation of sch 11 0.50 4.09 3.82 100.00
60 INT247862 Regulation of Narfl 1 0.06 0.67 0 100.00
61 INT274340 Regulation of Localization of NARFL 1 0.06 0.63 0 100.00
62 INT289495 Regulation of Positive_regulation of Narfl 1 0.04 0.59 0 100.00
63 INT289990 Positive_regulation of Gene_expression of Narf 1 0.02 0.77 0 100.00
64 INT227781 Positive_regulation of GON4L 4 0.13 7.56 0.54 100.00
65 INT289984 Regulation of Narf 1 0.01 0.78 0 100.00
66 INT325463 Positive_regulation of Binding of NARFL 2 0.15 0.76 0 100.00
67 INT274339 Negative_regulation of Binding of NARFL 1 0.06 0.58 0.17 100.00
68 INT259719 Negative_regulation of Regulation of NARFL 1 0.01 1.67 0 100.00
69 INT330979 Protein_catabolism of NARFL 1 0.02 0.84 0.06 100.00
70 INT325466 Positive_regulation of Localization of NARFL 1 0.04 0.53 0 100.00
71 INT51098 Positive_regulation of Negative_regulation of Nisch 1 0.01 0.5 0.1 100.00
72 INT51099 Negative_regulation of Nisch 6 0.43 0.97 2.93 100.00
73 INT10899 Positive_regulation of Gene_expression of Edn1 32 0.70 24.88 7.65 100.00
74 INT289993 Positive_regulation of Positive_regulation of Narf 1 0.02 0.85 0.08 100.00
75 INT289983 Regulation of Positive_regulation of Narf 1 0.01 1.12 0.46 100.00
76 INT347565 Positive_regulation of Gene_expression of Narfl 1 0.00 0.56 0.25 100.00
77 INT247879 Regulation of Gene_expression of Narfl 1 0.04 0.66 0 100.00
78 INT289992 Phosphorylation of Cntf 1 0.30 1 0.22 100.00
79 INT289982 Phosphorylation of CNTF 1 0.79 0.99 0.21 100.00
80 INT104568 Negative_regulation of Localization of Aqp1 1 0.36 2.47 0.2 100.00
81 INT247872 Positive_regulation of Gene_expression of Narfl 1 0.07 0.44 0 100.00
82 INT311459 Negative_regulation of Cle 1 0.20 0.3 0 100.00
83 INT289991 Phosphorylation of Narf 1 0.02 0.91 0.21 100.00
84 INT14843 Gene_expression of Gabrg1 301 0.77 62.63 139.16 100.00
85 INT5843 Positive_regulation of Gfap 184 0.70 108.2 70.21 99.98
86 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 99.98
87 INT340829 Positive_regulation of Arsi 1 0.02 1.76 0.39 99.98
88 INT322937 Negative_regulation of Positive_regulation of NARF 1 0.03 0.94 0 99.98
89 INT62979 Positive_regulation of ERG 11 0.25 4.5 1.48 99.98
90 INT286264 Positive_regulation of Negative_regulation of AQP1 1 0.01 0.79 0 99.98
91 INT108300 Positive_regulation of BCKDHA 3 0.39 1.74 0.18 99.98
92 INT153779 Positive_regulation of Dct 2 0.18 1.28 0.29 99.98
93 INT140991 Negative_regulation of Stat3 15 0.53 7.55 2.04 99.98
94 INT318313 Regulation of TST 2 0.34 0.23 0 99.98
95 INT130837 Gene_expression of Aqp4 205 0.78 151.23 29.63 99.96
96 INT170552 Regulation of Negative_regulation of Car2 3 0.39 1.97 0.07 99.96
97 INT20881 Negative_regulation of OPRK1 20 0.43 3.73 13.37 99.96
98 INT101203 Negative_regulation of Gene_expression of Calca 12 0.59 7.06 10.72 99.96
99 INT2520 Negative_regulation of Ca2 271 0.57 72.13 83.71 99.92
100 INT170546 Gene_expression of Renbp 15 0.32 14.33 0.72 99.90
101 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 99.90
102 INT54808 Positive_regulation of TIMM13 3 0.23 3.05 0.13 99.90
103 INT34870 Positive_regulation of OPA1 18 0.59 10.66 5 99.84
104 INT23564 Negative_regulation of Car2 103 0.50 27.28 21.86 99.84
105 INT165400 Positive_regulation of TST 13 0.68 4.25 0.35 99.84
106 INT225965 Localization of Aqp4 26 0.81 18.85 3.75 99.84
107 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 99.84
108 INT1951 Positive_regulation of Tlr4 345 0.70 176.99 62.42 99.84
109 INT247870 Negative_regulation of Localization of Aqp4 3 0.43 2 0.24 99.84
110 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37 99.84
111 INT3183 Negative_regulation of MRXS5 15 0.41 6.56 3.45 99.84
112 INT6196 Regulation of Nppa 83 0.62 30.31 30.18 99.84
113 INT89662 Positive_regulation of Gene_expression of App 169 0.70 133.36 25.62 99.84
114 INT285003 Positive_regulation of Regulation of Bcl2 1 0.46 0.68 0.23 99.84
115 INT59447 Negative_regulation of Tyr 12 0.56 4.57 3.32 99.82
116 INT174876 Regulation of Gene_expression of Fig4 18 0.39 7.83 2.44 99.82
117 INT44149 Regulation of Gene_expression of Mif 6 0.54 2.45 1.63 99.82
118 INT22548 Positive_regulation of Casp3 483 0.70 258.78 213.07 99.82
119 INT340830 Binding of Arsi 1 0.01 1.66 0.37 99.82
120 INT294399 Negative_regulation of Vav3 1 0.59 1.59 0 99.82
121 INT294405 Negative_regulation of Vav2 1 0.59 1.58 0 99.82
122 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 99.80
123 INT2611 Negative_regulation of AQP1 17 0.39 10.04 2.15 99.80
124 INT5781 Gene_expression of Edn1 190 0.78 99.1 46 99.80
125 INT49129 Positive_regulation of GFAP 35 0.69 28.78 10.38 99.80
126 INT16356 Regulation of NPPA 33 0.62 13.24 9.53 99.80
127 INT4057 Negative_regulation of Ptgfr 9 0.32 3.28 3 99.80
128 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 99.78
129 INT101147 Gene_expression of Uchl1 31 0.76 14.73 13.22 99.78
130 INT247882 Positive_regulation of Ube4a 4 0.01 2.17 0.07 99.76
131 INT174844 Binding of Fig4 81 0.41 18.03 12.87 99.74
132 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 99.72
133 INT247881 Regulation of Ube4a 1 0.00 3.69 0.03 99.68
134 INT22270 Regulation of IGKV1-5 13 0.39 3.56 3.54 99.68
135 INT131116 Localization of IGKV1-5 10 0.36 2.13 1.06 99.68
136 INT152710 Gene_expression of Dct 3 0.57 0.76 0.17 99.68
137 INT108252 Positive_regulation of Renbp 16 0.24 11.66 1.68 99.66
138 INT54809 Regulation of TIMM13 2 0.14 2.31 0.07 99.60
139 INT99444 Positive_regulation of Proc 15 0.45 9.18 1.75 99.60
140 INT107875 Phosphorylation of Stat3 49 0.80 13.18 12.66 99.60
141 INT121861 Regulation of BID 4 0.31 2.73 1.15 99.60
142 INT165773 Gene_expression of Darc 37 0.75 22.28 14.84 99.58
143 INT797 Regulation of Penk 812 0.62 111.13 542.24 99.56
144 INT5010 Gene_expression of Calca 197 0.78 85.76 118.75 99.56
145 INT353099 Positive_regulation of Ctrcts 1 0.01 1.63 0.16 99.54
146 INT20992 Regulation of ITGB2 11 0.37 9.04 1.73 99.52
147 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45 99.52
148 INT286266 Positive_regulation of Regulation of ITGB2 1 0.07 1.33 0.1 99.52
149 INT654 Localization of REN 250 0.81 75.12 47.86 99.48
150 INT235951 Positive_regulation of Positive_regulation of Aqp4 4 0.57 5.13 0.75 99.46
151 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 99.44
152 INT209419 Regulation of GPSM2 5 0.21 3.03 0.33 99.44
153 INT95272 Regulation of Gene_expression of Edn1 19 0.53 17.85 3.42 99.44
154 INT181268 Localization of GPSM2 3 0.35 2.49 0.44 99.44
155 INT93120 Localization of Gfap 21 0.78 8.42 3.7 99.44
156 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 99.40
157 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 99.40
158 INT97050 Negative_regulation of Uchl1 2 0.22 2.28 0.14 99.40
159 INT247884 Negative_regulation of Gene_expression of Uchl1 1 0.21 1.22 0 99.40
160 INT322938 Positive_regulation of NARF 1 0.04 0.94 0 99.38
161 INT8700 Positive_regulation of Positive_regulation of Calca 56 0.67 21.69 53.66 99.36
162 INT247874 Positive_regulation of Negative_regulation of Thy1 1 0.14 0.51 0 99.34
163 INT40750 Gene_expression of Mif 61 0.78 34.59 20.28 99.32
164 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 99.32
165 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 99.30
166 INT10506 Gene_expression of PTAFR 86 0.76 37.57 28.58 99.30
167 INT227780 Gene_expression of GON4L 2 0.13 2.72 0.05 99.28
168 INT158260 Gene_expression of Tnfrsf4 7 0.23 1.51 0.15 99.28
169 INT355407 Positive_regulation of Crybb2 1 0.40 1.69 0.13 99.26
170 INT136304 Negative_regulation of Aqp4 54 0.59 48.42 7.4 99.24
171 INT165821 Positive_regulation of Aqp4 27 0.70 24.37 3.22 99.24
172 INT169748 Positive_regulation of Gene_expression of Aqp4 38 0.69 34.29 3.79 99.24
173 INT32692 Positive_regulation of Aif1 33 0.35 13.29 9.03 99.14
174 INT247871 Negative_regulation of Thy1 8 0.54 7.23 0.03 99.12
175 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 99.08
176 INT4822 Localization of Ca2 417 0.80 99.57 96.45 99.06
177 INT6866 Regulation of Gfap 51 0.61 19.6 23.56 98.98
178 INT247861 Negative_regulation of Ube4a 1 0.00 2.02 0 98.98
179 INT289494 Regulation of 1190002H23Rik 1 0.04 1.64 0 98.94
180 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 98.92
181 INT12991 Negative_regulation of Gene_expression of PTGS1 28 0.41 13.39 8.9 98.92
182 INT55737 Positive_regulation of MMP2 101 0.68 59.11 27.71 98.92
183 INT278425 Binding of Tnfrsf4 2 0.03 1.3 0.44 98.88
184 INT1027 Gene_expression of Lbp 132 0.77 106.7 54.16 98.80
185 INT85976 Transcription of MYOC 1 0.16 1.68 0.55 98.80
186 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84 98.78
187 INT6054 Positive_regulation of Gene_expression of Egr1 67 0.70 18.45 25.93 98.76
188 INT138784 Positive_regulation of Gene_expression of Lcn2 3 0.49 4.44 1.13 98.76
189 INT94233 Positive_regulation of Gene_expression of Clu 3 0.69 2.64 0.71 98.76
190 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 98.72
191 INT10900 Positive_regulation of Positive_regulation of Nppb 3 0.41 3.53 0.21 98.72
192 INT1724 Negative_regulation of ACE 437 0.59 315.64 74.48 98.68
193 INT52179 Regulation of Lbp 39 0.61 25.4 18.32 98.68
194 INT37110 Positive_regulation of Ptgfr 10 0.69 2.38 3.44 98.68
195 INT286265 Negative_regulation of GPSM2 3 0.20 1.06 0.31 98.68
196 INT182516 Negative_regulation of Negative_regulation of ACE 9 0.42 6.84 0.99 98.68
197 INT293961 Binding of PITX1 1 0.31 1.73 0.1 98.68
198 INT4207 Regulation of Avp 267 0.62 63.72 115.33 98.60
199 INT9196 Gene_expression of PTGS1 215 0.77 96.99 60.5 98.60
200 INT12114 Positive_regulation of Tnfrsf1a 46 0.69 36.26 22.54 98.60
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