D:Oligospermia

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pChart

Disease Term
Synonyms Count Low Sperm, COUNTS LOW SPERM, Low Sperm Count, LOW SPERM COUNTS, OLIGOZOOSPERMIA, Sperm Count Low, Sperm Counts Low
Documents 22
Hot Single Events 29
Hot Interactions 1

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Oligospermia. They are ordered first by their relevance to Oligospermia and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT19633 GNRH1 Regulation of Localization of CGA 4 0.44 0.82 1.33 80.96
2 INT25248 GNRH1 Regulation of CGA 4 0.30 1.22 0.62 5.00
3 INT327806 Binding of ADORA1 and ADORA2A 1 0.06 0.18 0.49 5.00
4 INT327814 Rab8a Regulation of Regulation of Lep 1 0.01 0.15 0.19 5.00
5 INT327813 Rab8a Regulation of Lep 1 0.01 0.15 0.19 5.00
6 INT327808 EPO Regulation of VEGFA 1 0.07 1.36 0.12 5.00
7 INT186240 Binding of AGRP and SCN5A 2 0.13 1.19 0.1 5.00
8 INT327821 GPRC6A Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 5.00
9 INT327822 INCENP Regulation of Gene_expression of Lep 1 0.00 0.5 0.05 5.00
10 INT331883 Binding of MAGEA4 and GOPC 1 0.03 0 0 5.00
11 INT277803 Regulation of GNRH1 Regulation of CGA 1 0.00 0.61 0 5.00
12 INT327809 Binding of ADORA2B and IL8 1 0.03 0.3 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Oligospermia. They are ordered first by their pain relevance and then by number of times they were reported in Oligospermia. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5345 Positive_regulation of BRD2 14 0.67 6.72 3.43 99.88
2 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 99.38
3 INT9495 Negative_regulation of Gene_expression of Igf1 31 0.59 11.87 6.1 99.38
4 INT7395 Localization of GNRH1 399 0.81 62.88 117.68 99.36
5 INT3803 Negative_regulation of Igf1 45 0.58 15.95 7.98 99.18
6 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 98.90
7 INT1499 Negative_regulation of Gene_expression of Gh 58 0.42 25.17 7.86 98.90
8 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 98.84
9 INT26538 Positive_regulation of FSHR 103 0.69 30.95 15.33 98.50
10 INT2055 Regulation of Gnrh1 185 0.62 23.65 71.26 97.88
11 INT439 Localization of Gnrh1 976 0.81 100.96 363.25 97.88
12 INT11370 Positive_regulation of LHB 15 0.28 5.45 4.01 96.56
13 INT1793 Localization of CGA 379 0.81 67.38 114.69 96.48
14 INT99569 Positive_regulation of Negative_regulation of Shbg 3 0.40 0.53 0.44 96.08
15 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 93.48
16 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 92.96
17 INT528 Gene_expression of Prl 693 0.78 217.18 192.2 92.68
18 INT2296 Positive_regulation of Gene_expression of Prl 137 0.70 36.96 35.39 92.68
19 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 92.40
20 INT19636 Localization of HABP2 1 0.04 0.4 0.07 90.44
21 INT19635 Localization of SHBG 7 0.78 2.83 1.29 90.44
22 INT19637 Localization of TF 14 0.73 5.74 0.86 90.44
23 INT19638 Binding of HABP2 1 0.04 0.4 0.08 90.24
24 INT920 Localization of PLOD1 223 0.81 42.25 78.7 90.00
25 INT1361 Negative_regulation of Gnrhr 118 0.58 57.77 35.54 87.76
26 INT913 Regulation of Localization of PLOD1 71 0.62 8.64 32.72 85.76
27 INT116879 Gene_expression of MAGEA4 3 0.41 5.82 0.47 81.76
28 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 81.68
29 INT331886 Gene_expression of DDX4 1 0.12 2.38 0 80.80
30 INT158 Localization of Prl 2431 0.81 378.96 952.2 79.68
31 INT159 Negative_regulation of Localization of Prl 416 0.59 55.34 171.8 79.68
32 INT1530 Regulation of Gh 382 0.61 115.96 112.47 79.36
33 INT8916 Regulation of Igf1 45 0.60 13.06 5.81 78.16
34 INT133809 Negative_regulation of Gene_expression of CYP19A1 9 0.43 7.67 2.99 77.28
35 INT154527 Gene_expression of POU5F1 180 0.78 34.01 4.34 76.96
36 INT7396 Regulation of Localization of GNRH1 81 0.62 6.57 31.31 76.72
37 INT71047 Gene_expression of CYP19A1 122 0.78 68.78 22.21 76.40
38 INT282576 Negative_regulation of Gene_expression of POU5F1 12 0.43 2.79 0.16 74.88
39 INT6782 Gene_expression of SCN5A 156 0.78 33.13 17.88 73.60
40 INT281255 Positive_regulation of Negative_regulation of CDY1 1 0.28 1.64 0 67.72
41 INT281257 Positive_regulation of Positive_regulation of DAZ1 1 0.16 1.58 0 67.72
42 INT281252 Positive_regulation of DAZ1 1 0.16 1.56 0 65.80
43 INT281258 Negative_regulation of CDY1 1 0.23 1.61 0 65.00
44 INT917 Positive_regulation of Localization of PLOD1 51 0.69 8.53 22.87 61.48
45 INT912 Localization of FSHR 91 0.79 23.61 15.58 60.92
46 INT4145 Gene_expression of FSHR 124 0.77 44.98 13.04 60.08
47 INT7394 Positive_regulation of Localization of GNRH1 67 0.69 7.22 25.29 57.00
48 INT7970 Gene_expression of PLOD1 120 0.71 44.42 15.54 53.36
49 INT7972 Positive_regulation of Gene_expression of PLOD1 15 0.42 5.73 1.96 53.36
50 INT33496 Positive_regulation of Gene_expression of FSHR 14 0.46 6.05 1.66 52.80
51 INT95585 Negative_regulation of Pde12 18 0.43 8.32 11.23 52.56
52 INT119904 Regulation of CYP19A1 25 0.62 9.36 8.34 46.36
53 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 42.72
54 INT5131 Gene_expression of GNRH1 109 0.78 28.79 23.94 42.72
55 INT15609 Positive_regulation of Gene_expression of GNRH1 17 0.49 5.15 3.34 42.72
56 INT162 Regulation of Prl 794 0.62 165.01 322.24 40.80
57 INT327817 Negative_regulation of ADORA2A 1 0.17 1.83 0.27 38.88
58 INT3933 Positive_regulation of PLOD1 128 0.70 30.76 42.03 32.20
59 INT112003 Localization of ROS1 94 0.73 66.32 12.16 30.08
60 INT25031 Negative_regulation of Gene_expression of PLOD1 14 0.54 3.86 2.89 18.00
61 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
62 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
63 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
64 INT156 Negative_regulation of Prl 542 0.59 131.97 192.24 5.00
65 INT425 Localization of PRL 455 0.81 189.64 144.8 5.00
66 INT12339 Localization of IL8 437 0.81 251.87 117.39 5.00
67 INT915 Positive_regulation of PRL 342 0.70 141.96 104.31 5.00
68 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 5.00
69 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
70 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 5.00
71 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
72 INT1579 Gene_expression of PRL 279 0.78 119.2 55.41 5.00
73 INT251 Regulation of INS 398 0.62 232.47 55.04 5.00
74 INT9210 Regulation of IL6 166 0.62 125.61 49.95 5.00
75 INT619 Positive_regulation of Positive_regulation of Prl 116 0.70 22.69 45.06 5.00
76 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 5.00
77 INT69437 Positive_regulation of ROS1 328 0.58 222.83 40.56 5.00
78 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 5.00
79 INT916 Regulation of Localization of PRL 92 0.62 22.98 38.13 5.00
80 INT9239 Regulation of Gene_expression of IL6 106 0.61 75.24 36.53 5.00
81 INT1976 Regulation of Gene_expression of Prl 80 0.62 20.19 36 5.00
82 INT74563 Positive_regulation of Gene_expression of ROS1 258 0.61 168.18 34.08 5.00
83 INT48693 Regulation of VEGFA 268 0.62 191.88 31.52 5.00
84 INT7397 Negative_regulation of Localization of GNRH1 86 0.59 15.45 29.78 5.00
85 INT5135 Negative_regulation of GNRH1 106 0.58 36.63 27.71 5.00
86 INT5206 Gene_expression of AR 316 0.78 113.83 27.29 5.00
87 INT8779 Binding of TAC1 50 0.47 11.19 25.57 5.00
88 INT10835 Regulation of IL8 79 0.49 53.04 24.14 5.00
89 INT956 Negative_regulation of PRL 94 0.59 42.72 23.01 5.00
90 INT76123 Gene_expression of Lep 193 0.78 94.17 22.76 5.00
91 INT69322 Negative_regulation of MAPK14 70 0.54 42.92 22.71 5.00
92 INT3589 Positive_regulation of SCN5A 101 0.57 46.01 21.73 5.00
93 INT2005 Positive_regulation of Gene_expression of PRL 55 0.70 21.4 13.44 5.00
94 INT73641 Regulation of Lep 45 0.62 26.2 12.59 5.00
95 INT89395 Negative_regulation of AKT1 127 0.58 70.27 12.54 5.00
96 INT7234 Binding of GNRH1 43 0.47 21.59 12.36 5.00
97 INT3104 Negative_regulation of CGA 76 0.54 29.81 12.23 5.00
98 INT170601 Positive_regulation of Gene_expression of GOPC 122 0.43 42.79 11.68 5.00
99 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 5.00
100 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
101 INT94784 Binding of ROS1 113 0.40 71.57 10.26 5.00
102 INT82078 Negative_regulation of Lep 54 0.59 20.47 9.38 5.00
103 INT6510 Gene_expression of AFP 130 0.78 119.2 9.19 5.00
104 INT860 Regulation of ALB 48 0.60 25.11 8.95 5.00
105 INT82082 Localization of Lep 63 0.81 26.41 8.56 5.00
106 INT15872 Positive_regulation of EPO 74 0.70 45.35 6.67 5.00
107 INT137454 Gene_expression of ADIPOQ 88 0.78 85.32 6.2 5.00
108 INT104330 Negative_regulation of CDKN1A 57 0.58 39.93 5.88 5.00
109 INT23598 Binding of SCN5A 32 0.40 16 5.35 5.00
110 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
111 INT156794 Gene_expression of CISH 41 0.58 23.09 5.03 5.00
112 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
113 INT80421 Positive_regulation of IFI27 26 0.65 15.32 3.93 5.00
114 INT68255 Regulation of Positive_regulation of IL8 12 0.41 5.71 3.91 5.00
115 INT83433 Positive_regulation of ADIPOQ 40 0.69 34 3.67 5.00
116 INT5204 Positive_regulation of Gene_expression of AR 60 0.67 23.54 3.53 5.00
117 INT79477 Binding of HLA-DMA 19 0.26 13.78 3.47 5.00
118 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05 5.00
119 INT16447 Binding of IL1A 10 0.45 4.01 2.78 5.00
120 INT204340 Localization of ADIPOQ 20 0.75 25.18 2.64 5.00
121 INT188756 Positive_regulation of AGRP 43 0.60 23.67 2.51 5.00
122 INT92141 Negative_regulation of CDKN2A 53 0.57 44.23 2.48 5.00
123 INT111451 Regulation of ADIPOQ 24 0.56 18.81 2.47 5.00
124 INT15607 Localization of GNRHR 14 0.62 7.56 2.3 5.00
125 INT110184 Binding of HMI 9 0.28 5.52 2.24 5.00
126 INT82081 Regulation of Gene_expression of Lep 11 0.53 7.78 2.12 5.00
127 INT7116 Localization of Rab8a 10 0.70 1.2 1.95 5.00
128 INT32558 Negative_regulation of ADORA1 5 0.12 2.77 1.86 5.00
129 INT82083 Negative_regulation of Gene_expression of Lep 12 0.56 8.07 1.75 5.00
130 INT84722 Regulation of Gene_expression of AR 20 0.61 7.73 1.69 5.00
131 INT143443 Localization of HIF1A 14 0.78 10.93 1.49 5.00
132 INT64952 Binding of HLA-DQA2 11 0.10 7.23 1.39 5.00
133 INT10873 Localization of Twist1 21 0.74 10.43 1.37 5.00
134 INT282590 Positive_regulation of Gene_expression of POU5F1 40 0.70 8.42 1.32 5.00
135 INT134663 Gene_expression of SOX9 40 0.75 9.07 1.2 5.00
136 INT213277 Positive_regulation of Gene_expression of ADIPOQ 14 0.50 17.7 1.14 5.00
137 INT282572 Positive_regulation of POU5F1 24 0.70 5.8 1.13 5.00
138 INT82084 Positive_regulation of Localization of Lep 11 0.70 4.65 1.11 5.00
139 INT204254 Localization of KIT 8 0.73 6.78 0.61 5.00
140 INT55047 Gene_expression of GNRHR 8 0.78 5.2 0.53 5.00
141 INT94165 Negative_regulation of RB1 30 0.52 27.29 0.51 5.00
142 INT127273 Gene_expression of AMH 24 0.78 9.53 0.47 5.00
143 INT125592 Negative_regulation of Negative_regulation of CDKN1A 2 0.42 2.07 0.41 5.00
144 INT127274 Positive_regulation of Gene_expression of AMH 5 0.61 1.4 0.29 5.00
145 INT327805 Positive_regulation of Rab8a 1 0.07 1.31 0.29 5.00
146 INT206159 Negative_regulation of Regulation of VEGFA 3 0.24 2.38 0.2 5.00
147 INT327818 Binding of GPRC6A 3 0.01 0.28 0.13 5.00
148 INT105066 Negative_regulation of Rab8a 2 0.26 0.64 0.11 5.00
149 INT327816 Regulation of Positive_regulation of ADIPOQ 1 0.04 1.2 0.09 5.00
150 INT143444 Positive_regulation of Localization of HIF1A 3 0.45 1.26 0.06 5.00
151 INT281251 Negative_regulation of LAMTOR1 1 0.12 1.42 0 5.00
152 INT331887 Positive_regulation of DDX4 1 0.07 0 0 5.00
153 INT281254 Negative_regulation of Negative_regulation of CDKN2A 1 0.08 1.44 0 5.00
154 INT247431 Positive_regulation of Negative_regulation of RB1 2 0.45 2.58 0 5.00
155 INT281256 Positive_regulation of CCND2 1 0.20 1.42 0 5.00
156 INT281253 Negative_regulation of Negative_regulation of LAMTOR1 1 0.09 1.49 0 5.00
157 INT331884 Localization of MAGEA4 1 0.17 0 0 5.00
158 INT331888 Positive_regulation of MAGEA4 1 0.13 0 0 5.00
159 INT331890 Localization of DDX4 1 0.11 0 0 5.00
160 INT211184 Positive_regulation of Binding of SCN5A 1 0.22 0.48 0 5.00
161 INT327819 Localization of ADORA2B 1 0.22 0.3 0 5.00
162 INT282585 Localization of POU5F1 3 0.67 0.08 0 5.00
163 INT331889 Positive_regulation of Gene_expression of DDX4 1 0.08 0.06 0 5.00
164 INT211183 Binding of PGD 2 0.31 0.71 0 5.00
165 INT251628 Negative_regulation of CDKN2D 2 0.15 1.83 0 5.00
166 INT281250 Negative_regulation of Negative_regulation of CDKN2D 1 0.08 1.49 0 5.00
167 INT331885 Positive_regulation of Gene_expression of MAGEA4 1 0.13 0.06 0 5.00
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