D:Postmenopausal Osteoporosis

From wiki-pain
Revision as of 14:58, 13 October 2012 by Daniel (Talk | contribs)

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

pChart

Disease Term
Synonyms BONE LOSS PERIMENOPAUSAL, Bone Loss Postmenopausal, Bone Losses Perimenopausal, BONE LOSSES POSTMENOPAUSAL, Osteoporoses Post Menopausal, Osteoporoses Postmenopausal, OSTEOPOROSIS POST MENOPAUSAL, Perimenopausal Bone Loss, Perimenopausal Bone Losses, Post Menopausal Osteoporoses, Post Menopausal Osteoporosis
Documents 283
Hot Single Events 88
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Postmenopausal Osteoporosis. They are ordered first by their relevance to Postmenopausal Osteoporosis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT270135 Binding of ESR1 and RALA 1 0.11 0.37 0.22 98.88
2 INT334043 Cdt1 Positive_regulation of Gene_expression of ALPP 1 0.08 0.39 0.05 94.96
3 INT302311 PTH Negative_regulation of Gene_expression of SOST 1 0.29 0.59 0 94.56
4 INT107910 Binding of Tnfrsf11b and Tnfsf11 6 0.30 5.88 0.7 83.04
5 INT172125 Binding of Tnfrsf11b and Tnfrsf11a 2 0.17 2.12 0.39 83.04
6 INT270134 BPs Negative_regulation of FDPS 1 0.01 0.36 0.05 79.56
7 INT335882 Dkk1 Negative_regulation of Wnt2 1 0.02 0.15 0 72.84
8 INT277622 Esr1 Positive_regulation of Gene_expression of Cyp19a1 1 0.03 1.37 0 70.36
9 INT183614 Binding of ESR1 and TMED4 2 0.02 0.13 0.03 70.00
10 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 68.64
11 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 63.84
12 INT210597 Negative_regulation of Binding of TNFSF11 and TNFRSF11A 3 0.26 5.66 0.33 63.84
13 INT341728 Pth Positive_regulation of Best1 1 0.06 0.43 0 61.56
14 INT171974 Binding of Tnfrsf11a and Tnfsf11 14 0.35 13.11 3.11 55.84
15 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 50.00
16 INT210596 TNFRSF11B Negative_regulation of Binding of TNFSF11 2 0.11 1.62 0.04 50.00
17 INT210593 TNFRSF11B Negative_regulation of Binding of TNFSF11 and TNFRSF11A 2 0.10 1.62 0.04 50.00
18 INT329479 Binding of TNFRSF11B and TNF 1 0.04 0.71 0 50.00
19 INT329480 Binding of TNFRSF11B and TNFSF10 1 0.03 0.71 0 50.00
20 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5 42.04
21 INT270116 DMD Regulation of St13 1 0.01 0.09 0 42.04
22 INT270775 PTH Regulation of DMD 1 0.09 0.64 0.03 38.56
23 INT270776 PTH Regulation of Negative_regulation of DMD 1 0.09 0.3 0.03 38.56
24 INT188801 Il6 Positive_regulation of Positive_regulation of Tnfsf11 1 0.06 0.46 0.21 32.24
25 INT254433 Binding of Lrp5 and Sost 2 0.39 1.51 0.03 9.44
26 INT185733 Hpse Positive_regulation of Gene_expression of Tnfrsf11b 1 0.20 0.24 0 8.96
27 INT188802 Il1 Negative_regulation of Gene_expression of Col7a1 1 0.00 0.71 0.26 6.24
28 INT115367 Binding of IL6 and IL6R 12 0.07 8.16 2.36 5.00
29 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
30 INT183781 Binding of IL6 and INS 6 0.22 8.97 1.87 5.00
31 INT131185 PTH Positive_regulation of Gene_expression of IGF1 3 0.44 3.31 1.31 5.00
32 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18 5.00
33 INT206074 Binding of IL6 and IL6ST 7 0.32 3.79 1.01 5.00
34 INT188805 TNF Positive_regulation of Gene_expression of Crp 1 0.15 2.96 0.95 5.00
35 INT188803 Il1 Positive_regulation of Gene_expression of Crp 1 0.03 2.95 0.94 5.00
36 INT207391 Il17a Positive_regulation of Gene_expression of Tnfsf11 2 0.05 1.19 0.77 5.00
37 INT64956 IRF6 Positive_regulation of Gene_expression of IL6 4 0.19 1.4 0.63 5.00
38 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56 5.00
39 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56 5.00
40 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56 5.00
41 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55 5.00
42 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55 5.00
43 INT207396 IL6 Positive_regulation of Gene_expression of Tnfsf11 1 0.03 0.95 0.51 5.00
44 INT207394 IL1B Positive_regulation of Gene_expression of Tnfsf11 1 0.05 0.95 0.51 5.00
45 INT207395 TNF Regulation of Gene_expression of Tnfsf11 1 0.11 0.91 0.49 5.00
46 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48 5.00
47 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48 5.00
48 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48 5.00
49 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48 5.00
50 INT115186 IL6 Positive_regulation of Phosphorylation of STAT3 2 0.19 0.35 0.48 5.00
51 INT264295 Binding of DMD and IGF1 1 0.07 1.38 0.44 5.00
52 INT146611 Ins1 Positive_regulation of Phosphorylation of Akt1 9 0.23 4.34 0.37 5.00
53 INT352547 Binding of CFTR and DMD 1 0.01 1.42 0.35 5.00
54 INT188804 S100a8 Positive_regulation of Gene_expression of Tnfsf11 1 0.00 0.7 0.31 5.00
55 INT257577 CALCA Positive_regulation of DMD 1 0.01 0.57 0.26 5.00
56 INT173558 CTSK Positive_regulation of Protein_catabolism of COL5A2 1 0.00 0.53 0.22 5.00
57 INT335888 Lrp5 Negative_regulation of Gene_expression of Tph1 1 0.22 0.15 0.21 5.00
58 INT264298 NOL3 Negative_regulation of CRP 1 0.39 0.49 0.2 5.00
59 INT206089 Negative_regulation of FOSB Negative_regulation of Gene_expression of PTGS2 1 0.00 0.97 0.19 5.00
60 INT206081 IL6ST Negative_regulation of IL6 1 0.11 0.81 0.17 5.00
61 INT206059 IL6 Positive_regulation of INS 1 0.02 1.16 0.16 5.00
62 INT173599 Binding of MMP1 and Mmp1a 1 0.06 0.5 0.15 5.00
63 INT206070 ANG Positive_regulation of Transcription of IL6 1 0.05 1.5 0.15 5.00
64 INT334541 Binding of HIVEP1 and TNF 1 0.01 1.32 0.13 5.00
65 INT206065 EDN1 Positive_regulation of IL6 1 0.03 0.47 0.12 5.00
66 INT236588 Binding of Esr1 and Ins1 1 0.05 0.73 0.12 5.00
67 INT334044 Cdt1 Regulation of Gene_expression of ALPP 1 0.04 0.72 0.12 5.00
68 INT206056 PTK2B Negative_regulation of Positive_regulation of IRF6 1 0.00 0.66 0.1 5.00
69 INT352555 DKK1 Positive_regulation of Wnt2 1 0.01 0.25 0.1 5.00
70 INT206042 Negative_regulation of FDPS Negative_regulation of Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
71 INT206054 RAC1 Positive_regulation of STAT3 1 0.07 0.11 0.09 5.00
72 INT206075 Negative_regulation of FDPS Negative_regulation of Binding of GGPS1 1 0.01 0 0.09 5.00
73 INT206078 Binding of FDPS and GGPS1 1 0.00 0 0.09 5.00
74 INT270777 Binding of DMD and BPs 1 0.01 0.33 0.09 5.00
75 INT206072 ANG Positive_regulation of IL6 1 0.05 0.5 0.08 5.00
76 INT213933 AR Negative_regulation of Cyp19a1 1 0.07 0.79 0.07 5.00
77 INT206080 ANG Regulation of Gene_expression of IL6 1 0.03 0.4 0.07 5.00
78 INT335890 Binding of Dkk1 and Lrp4 1 0.37 0.64 0.07 5.00
79 INT335886 Binding of Sost and Lrp4 1 0.28 0.65 0.07 5.00
80 INT264300 CTSK Positive_regulation of CYP27A1 1 0.03 0.69 0.07 5.00
81 INT206063 ANG Positive_regulation of Gene_expression of KRT20 1 0.00 1.01 0.07 5.00
82 INT339779 IGF1 Regulation of GHRH 1 0.08 0.38 0.05 5.00
83 INT340274 Cd14 Regulation of Gene_expression of TNFRSF11A 1 0.05 0.8 0.05 5.00
84 INT339778 Binding of EDNRA and PTH 1 0.12 0.35 0.05 5.00
85 INT206087 RAC1 Positive_regulation of Gene_expression of STAT3 1 0.08 0.05 0.05 5.00
86 INT236591 Binding of Esr1 and Positive_regulation of Tmed4 1 0.04 0.52 0.05 5.00
87 INT340271 Fig4 Positive_regulation of Localization of RELA 1 0.01 0.68 0.04 5.00
88 INT206083 LDLR Positive_regulation of Binding of STAT3 1 0.02 0.53 0.04 5.00
89 INT206073 Negative_regulation of RAC1 Positive_regulation of IL6 1 0.14 0.06 0.04 5.00
90 INT236596 Ncoa2 Positive_regulation of PELP1 1 0.36 0.17 0.04 5.00
91 INT206067 Gene_expression of RAC1 Positive_regulation of Positive_regulation of IL6 1 0.16 0.07 0.04 5.00
92 INT236595 Binding of Esr1 and PELP1 1 0.27 0.17 0.04 5.00
93 INT225493 Binding of Esr1 and Pprc1 2 0.01 0.17 0.04 5.00
94 INT340273 Fig4 Regulation of BGLAP 1 0.00 0.55 0.04 5.00
95 INT206068 RAC1 Positive_regulation of IL6 1 0.16 0.06 0.04 5.00
96 INT206066 LDLR Positive_regulation of Phosphorylation of STAT3 1 0.02 0.52 0.04 5.00
97 INT206071 IRF6 Positive_regulation of Positive_regulation of IL1B 1 0.00 0.58 0.03 5.00
98 INT199526 Ceacam1 Negative_regulation of Col1a1 1 0.01 0.06 0.03 5.00
99 INT236586 Binding of Ncoa2 and Psmd4 1 0.12 0.22 0.03 5.00
100 INT269759 PTH Positive_regulation of DMD 2 0.06 0.37 0.03 5.00
101 INT206076 IL6 Positive_regulation of Positive_regulation of STAT3 1 0.19 0.3 0.03 5.00
102 INT236590 Binding of Adipoq and Ncoa2 1 0.15 0.2 0.03 5.00
103 INT236597 Ncoa1 Positive_regulation of PELP1 1 0.41 0.17 0.03 5.00
104 INT206061 RAC1 Positive_regulation of Positive_regulation of STAT3 1 0.07 0.43 0.03 5.00
105 INT236587 Binding of Adipoq and Ncoa1 1 0.17 0.2 0.03 5.00
106 INT236592 Positive_regulation of Binding of Adipoq and Ncoa2 1 0.19 0.2 0.03 5.00
107 INT199527 Ceacam1 Negative_regulation of CYP27A1 1 0.02 0.06 0.03 5.00
108 INT236585 Ncoa2 Positive_regulation of Transcription of Ncoa1 1 0.27 0.23 0.03 5.00
109 INT340276 Tnfsf11 Positive_regulation of Localization of RELA 1 0.02 0.58 0.03 5.00
110 INT174532 PTH Positive_regulation of Transcription of IGF1 1 0.06 0.51 0 5.00
111 INT340214 BGLAP Regulation of Gene_expression of NFATC1 1 0.02 0.76 0 5.00
112 INT340270 Negative_regulation of Tnfsf11 Positive_regulation of TRAP 1 0.03 0.37 0 5.00
113 INT206085 FDPS Positive_regulation of AGFG1 1 0.00 0.4 0 5.00
114 INT206058 EGFR Negative_regulation of Gene_expression of IL6 1 0.07 0.62 0 5.00
115 INT206079 ANG Regulation of KRT20 1 0.00 0.54 0 5.00
116 INT206069 ANG Positive_regulation of Gene_expression of IL6 1 0.05 0.51 0 5.00
117 INT302321 Negative_regulation of Binding of Lrp6 and SOST 1 0.16 0.26 0 5.00
118 INT302322 Negative_regulation of Binding of Lrp5 and SOST 1 0.16 0.26 0 5.00
119 INT340275 NFATC1 Positive_regulation of Binding of Ahr 1 0.10 0.51 0 5.00
120 INT335884 Akt1 Regulation of Positive_regulation of Wnt5a 1 0.03 0.15 0 5.00
121 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0 5.00
122 INT181311 Binding of DMD and KRT20 1 0.01 0.07 0 5.00
123 INT270780 BPs Positive_regulation of DMD 1 0.02 0 0 5.00
124 INT206178 Foxm1 Positive_regulation of Protein_catabolism of Olr1 1 0.00 0.47 0 5.00
125 INT206086 LDLR Positive_regulation of Localization of IL6 1 0.03 0.42 0 5.00
126 INT206060 FDPS Positive_regulation of AKT1 1 0.00 0.4 0 5.00
127 INT206055 F2 Positive_regulation of Gene_expression of IL6 1 0.01 1.24 0 5.00
128 INT257589 Negative_regulation of Pth Positive_regulation of DMD 1 0.01 0 0 5.00
129 INT206082 IL6 Positive_regulation of Gene_expression of CCL2 1 0.07 0.3 0 5.00
130 INT302320 Binding of Lrp6 and SOST 1 0.18 0.26 0 5.00
131 INT264297 Binding of IGF1 and NOL3 1 0.36 0.44 0 5.00
132 INT206180 Foxm1 Positive_regulation of Transcription of Olr1 1 0.00 0.48 0 5.00
133 INT257590 Pth Positive_regulation of DMD 2 0.02 0.44 0 5.00
134 INT335887 Akt1 Regulation of Lrp6 1 0.06 0.15 0 5.00
135 INT302323 Binding of SOST and Wnt2 1 0.02 0.26 0 5.00
136 INT302319 Binding of Lrp5 and SOST 1 0.18 0.26 0 5.00
137 INT270778 Binding of TNFSF11 and CALCRL 1 0.00 0.44 0 5.00
138 INT335883 Binding of Lrp6 and Wnt5a 1 0.27 0.08 0 5.00
139 INT211067 Pth Regulation of DMD 1 0.01 0.12 0 5.00
140 INT335891 Binding of Dkk1 and Lrp5 1 0.39 0.57 0 5.00
141 INT206077 RAC1 Positive_regulation of Phosphorylation of STAT3 1 0.07 0.35 0 5.00
142 INT206181 FDPS Positive_regulation of ras 1 0.00 0.4 0 5.00
143 INT340277 Tnfsf11 Positive_regulation of TRAP 1 0.03 0.76 0 5.00
144 INT332159 Gh Positive_regulation of Gene_expression of Igfbp3 1 0.07 1.11 0 5.00
145 INT270122 Binding of Pth and Pc 1 0.05 0.1 0 5.00
146 INT209444 Stam Positive_regulation of Syk 1 0.01 0.26 0 5.00
147 INT340272 Tnfsf11 Positive_regulation of Gene_expression of NFATC1 1 0.09 0.56 0 5.00
148 INT270121 Binding of Pth and Pthlh 1 0.08 0.56 0 5.00
149 INT340238 Tnfsf11 Positive_regulation of Gene_expression of Fig4 1 0.02 0.4 0 5.00
150 INT264299 Binding of DMD and NOL3 1 0.05 0 0 5.00
151 INT206084 EGF Negative_regulation of Gene_expression of IL6 1 0.05 0.61 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Postmenopausal Osteoporosis. They are ordered first by their pain relevance and then by number of times they were reported in Postmenopausal Osteoporosis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT349060 Regulation of Negative_regulation of HHIP 1 0.10 1.33 0 100.00
2 INT28094 Binding of PTH 29 0.37 13.57 3.09 99.92
3 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 99.70
4 INT171998 Binding of DMD 58 0.47 38.13 3.35 99.68
5 INT4241 Regulation of CALCA 87 0.62 28.19 55.29 99.44
6 INT178766 Negative_regulation of HHIP 19 0.28 11.1 0.43 99.36
7 INT245157 Negative_regulation of Gene_expression of DMD 8 0.57 4.79 0.09 98.52
8 INT153627 Binding of Mapk1 5 0.36 2.88 1.4 98.36
9 INT2649 Regulation of Calca 433 0.62 146.05 330.95 98.32
10 INT13396 Gene_expression of DMD 125 0.75 57.81 5.45 98.16
11 INT93534 Gene_expression of Tnfsf11 185 0.77 119.26 33.66 98.12
12 INT171962 Gene_expression of Tnfrsf11a 40 0.72 31.1 7.84 98.12
13 INT144490 Regulation of Gene_expression of Tnfsf11 14 0.58 14.09 2.39 98.12
14 INT16165 Regulation of DMD 114 0.60 35.13 3.64 98.08
15 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 97.84
16 INT20462 Binding of ESR1 210 0.44 102.7 26.34 97.68
17 INT270117 Regulation of Ttc21b 1 0.00 0.1 0 97.68
18 INT133316 Localization of CTSK 5 0.52 2.43 0.43 96.88
19 INT22083 Regulation of Pth 55 0.62 22.32 8.9 96.84
20 INT335876 Negative_regulation of Sost 11 0.51 6.77 0.67 96.68
21 INT6665 Gene_expression of FOS 520 0.77 165.31 217.66 96.44
22 INT197372 Gene_expression of Tmie 16 0.51 9.08 1.9 96.20
23 INT261242 Binding of Tmed4 7 0.04 3.56 1.07 95.68
24 INT174541 Positive_regulation of Gene_expression of COL5A2 18 0.36 14.17 2.12 95.64
25 INT125477 Gene_expression of HHIP 91 0.78 31.18 12.57 95.44
26 INT125479 Positive_regulation of HHIP 38 0.44 12.39 3.75 95.36
27 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 95.32
28 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 95.08
29 INT34590 Gene_expression of ALPP 199 0.75 89.85 15.1 94.96
30 INT34592 Positive_regulation of Gene_expression of ALPP 51 0.67 20.62 5.68 94.96
31 INT34594 Negative_regulation of Gene_expression of ALPP 12 0.50 5.04 1.41 94.96
32 INT129883 Gene_expression of Dkk1 56 0.77 45.42 12.52 94.52
33 INT38373 Positive_regulation of Ap3b1 4 0.37 1.01 0.86 94.36
34 INT130867 Gene_expression of TNFSF11 106 0.77 45.15 10.34 94.24
35 INT130866 Positive_regulation of Gene_expression of TNFSF11 25 0.69 7.11 1.82 94.24
36 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73 93.36
37 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 93.28
38 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33 93.04
39 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 92.00
40 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 91.88
41 INT4067 Negative_regulation of Esr1 97 0.50 43.45 17.52 91.84
42 INT209893 Positive_regulation of Gene_expression of TNFRSF11B 31 0.68 11.77 4.8 91.64
43 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46 91.64
44 INT89484 Gene_expression of TNFRSF11B 119 0.76 53.57 19.67 91.24
45 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 91.16
46 INT132846 Localization of Tnfsf11 17 0.69 10.28 2.78 89.12
47 INT143395 Regulation of CYP27A1 25 0.53 9.01 2.18 88.88
48 INT257588 Regulation of Negative_regulation of DMD 2 0.03 0.96 0.14 88.88
49 INT211968 Localization of Best1 11 0.40 9.33 0.38 88.72
50 INT117205 Transcription of Esr1 23 0.65 9.4 4.14 88.36
51 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 88.32
52 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 88.20
53 INT6515 Gene_expression of BGLAP 110 0.75 45.13 10.81 88.16
54 INT8915 Gene_expression of Igf1 199 0.78 78.58 32.51 88.16
55 INT8916 Regulation of Igf1 45 0.60 13.06 5.81 88.16
56 INT4864 Regulation of BGLAP 22 0.34 10.8 5.07 88.16
57 INT9500 Negative_regulation of Ceacam1 26 0.58 6.89 3.91 87.96
58 INT50058 Negative_regulation of Cpox 907 0.58 426.28 428.29 87.76
59 INT171994 Regulation of Positive_regulation of DMD 4 0.15 0.82 0 87.48
60 INT6580 Negative_regulation of Ptgs1 929 0.59 381.53 376.26 87.36
61 INT302316 Negative_regulation of Gene_expression of SOST 4 0.51 1.36 0.05 86.56
62 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 86.24
63 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 86.24
64 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 86.24
65 INT341725 Regulation of Positive_regulation of Best1 1 0.07 0.26 0 85.92
66 INT302313 Gene_expression of SOST 6 0.67 2.06 0.08 85.64
67 INT274020 Phosphorylation of PTH 2 0.71 1.39 0.08 85.52
68 INT211969 Positive_regulation of Best1 34 0.11 14.92 1.44 85.20
69 INT62570 Binding of Pth 48 0.48 26.45 4.85 84.40
70 INT112054 Negative_regulation of Negative_regulation of DMD 12 0.44 5.02 0.45 83.72
71 INT104908 Binding of B4GALNT1 7 0.05 4.62 0.82 83.52
72 INT287182 Negative_regulation of Binding of B4GALNT1 1 0.03 0.48 0.04 83.52
73 INT32515 Negative_regulation of B4GALNT1 82 0.43 28.1 17.46 83.52
74 INT7232 Regulation of Negative_regulation of Lhb 9 0.45 3.63 3.29 82.92
75 INT2262 Negative_regulation of Lhb 142 0.59 25.47 44.81 82.48
76 INT3602 Negative_regulation of Shbg 148 0.53 69.05 11.65 82.48
77 INT19844 Negative_regulation of Gene_expression of Lhb 12 0.51 3.19 2.97 82.48
78 INT16202 Negative_regulation of Positive_regulation of Shbg 8 0.58 5.24 1.86 82.48
79 INT211970 Negative_regulation of Best1 49 0.14 37.33 2.32 82.24
80 INT2544 Localization of PTH 39 0.81 30.55 2.22 82.08
81 INT341693 Positive_regulation of Regulation of DMD 1 0.02 0.4 0 81.88
82 INT201524 Localization of Wnt2 14 0.62 9.24 0.46 81.76
83 INT2261 Gene_expression of Lhb 121 0.77 42.78 26.04 81.72
84 INT3300 Positive_regulation of Gene_expression of Calca 179 0.70 77.76 144.2 81.60
85 INT173808 Positive_regulation of CYP27A1 35 0.68 23.7 7.87 81.44
86 INT2630 Positive_regulation of Shbg 134 0.70 65.26 15.19 81.12
87 INT6512 Gene_expression of PTH 103 0.77 76.29 6.33 80.32
88 INT217763 Regulation of RALA 3 0.29 1.48 0 80.04
89 INT17458 Negative_regulation of Gene_expression of FOS 98 0.57 36.77 55.69 79.52
90 INT236594 Regulation of PELP1 1 0.44 0.24 0.11 79.52
91 INT182981 Binding of PELP1 2 0.36 0.24 0.11 79.52
92 INT236593 Regulation of Binding of PELP1 1 0.44 0.24 0.11 79.52
93 INT52180 Binding of Aes 38 0.42 23.16 6.7 79.04
94 INT124374 Binding of Wnt2 21 0.31 10.16 0.99 79.00
95 INT744 Positive_regulation of PTH 130 0.70 95.02 11.7 78.76
96 INT176571 Negative_regulation of Positive_regulation of ESR1 5 0.47 3.15 0.17 77.28
97 INT11491 Positive_regulation of KNG1 128 0.67 60.41 58.74 76.72
98 INT17250 Negative_regulation of BGLAP 35 0.57 21 8.26 76.48
99 INT274022 Regulation of Positive_regulation of TNFSF11 1 0.05 0.29 0 76.16
100 INT130865 Positive_regulation of TNFSF11 29 0.69 12.82 2.99 76.16
101 INT19132 Gene_expression of CYP27A1 83 0.75 34.31 10.17 76.12
102 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 76.12
103 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 75.92
104 INT10824 Negative_regulation of Cyp19a1 38 0.57 25.18 3.56 75.52
105 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98 75.36
106 INT181690 Gene_expression of PGRMC1 2 0.06 0.35 0.08 75.36
107 INT246574 Protein_catabolism of PPA1 1 0.01 0.62 0.03 75.32
108 INT180578 Regulation of HEYL 3 0.06 3.15 0.49 75.24
109 INT38674 Regulation of KRT20 32 0.44 19 2.15 75.12
110 INT79299 Negative_regulation of NXT1 16 0.32 8.27 3.78 75.00
111 INT79298 Localization of NXT1 9 0.60 4.9 3.42 75.00
112 INT4860 Positive_regulation of CALCA 148 0.00 73.35 97.61 75.00
113 INT6516 Positive_regulation of BGLAP 45 0.67 26.61 9.9 75.00
114 INT35269 Localization of SGCG 38 0.78 14.68 9.01 75.00
115 INT6513 Positive_regulation of Gene_expression of BGLAP 24 0.67 11.69 3.96 75.00
116 INT161840 Gene_expression of Tnfrsf11b 17 0.78 12.44 2.63 75.00
117 INT166467 Negative_regulation of Gene_expression of Tnfrsf11b 6 0.50 5.5 2.04 75.00
118 INT165393 Positive_regulation of Localization of NXT1 1 0.07 0.83 0.66 75.00
119 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 74.64
120 INT20461 Binding of Esr1 34 0.48 9.58 3.66 73.76
121 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17 73.68
122 INT5398 Positive_regulation of ALPP 178 0.70 110.52 19.18 73.28
123 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 72.12
124 INT8246 Positive_regulation of IL36RN 13 0.43 9.15 3.16 72.12
125 INT195058 Positive_regulation of Gene_expression of ALPL 3 0.65 1.56 0.42 71.80
126 INT302314 Negative_regulation of SOST 5 0.44 2.22 0.33 71.76
127 INT302317 Positive_regulation of Gene_expression of SOST 4 0.60 1.58 0.08 71.76
128 INT329487 Positive_regulation of Negative_regulation of SOST 1 0.45 0.62 0.05 71.76
129 INT195060 Gene_expression of ALPL 9 0.73 4.82 1.3 71.24
130 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 71.12
131 INT24410 Negative_regulation of Gene_expression of Serpinc1 4 0.28 1.98 0.91 71.12
132 INT28952 Negative_regulation of Gene_expression of IGF1 75 0.58 41.11 12.32 70.64
133 INT95667 Positive_regulation of Nfkb2 3 0.22 3.95 0.8 70.56
134 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11 70.36
135 INT52879 Negative_regulation of ATP6V0A1 2 0.24 0.64 0.82 70.20
136 INT183618 Binding of TMED4 12 0.15 2.22 1.21 70.00
137 INT296901 Positive_regulation of Gene_expression of Tmie 2 0.29 1.29 0 69.88
138 INT125480 Regulation of HHIP 17 0.38 6.16 2.16 69.88
139 INT227759 Gene_expression of Best1 26 0.42 20.36 1.73 69.76
140 INT250351 Positive_regulation of Gene_expression of Best1 5 0.27 3.14 0.65 69.76
141 INT2730 Positive_regulation of LTBR 4 0.48 2.37 1.06 69.44
142 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 69.12
143 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 69.12
144 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 68.24
145 INT254427 Binding of Lrp5 10 0.48 5.43 0.26 68.08
146 INT108519 Binding of Lrp6 8 0.44 1.47 1.19 68.08
147 INT211972 Regulation of Best1 18 0.33 12.04 0.67 68.04
148 INT9089 Positive_regulation of Ceacam1 17 0.69 7.09 2.49 67.92
149 INT9118 Gene_expression of Ceacam1 37 0.75 17.19 6.12 65.68
150 INT180145 Gene_expression of THOP1 15 0.28 5.94 0.36 64.72
151 INT68091 Localization of COL1A1 19 0.66 9.13 2.56 64.68
152 INT19131 Localization of CYP27A1 14 0.80 8.19 2.15 64.68
153 INT703 Positive_regulation of Pth 177 0.70 127.09 27.26 64.52
154 INT210608 Negative_regulation of Binding of TNFSF11 2 0.25 2.31 0.04 64.00
155 INT93016 Binding of TNFRSF11A 29 0.47 19.67 4.17 63.84
156 INT105537 Regulation of Gene_expression of Igf1 15 0.58 6.97 3.23 63.76
157 INT235398 Regulation of Gene_expression of BGLAP 3 0.27 1.03 0.61 63.76
158 INT182643 Binding of TNFSF11 15 0.35 13.12 1.61 63.60
159 INT221486 Positive_regulation of Binding of TNFSF11 1 0.15 0.98 0 63.60
160 INT62068 Transcription of Pth 6 0.67 3.2 0.23 63.48
161 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 62.96
162 INT6624 Gene_expression of Pth 135 0.76 110.27 27.54 62.84
163 INT192687 Negative_regulation of PAX5 9 0.40 1.42 0.08 62.64
164 INT132717 Localization of PAX5 3 0.50 1.27 0.03 62.64
165 INT338125 Gene_expression of GET4 1 0.29 2.74 0.32 62.44
166 INT2490 Regulation of Sct 44 0.62 9.45 13.11 62.32
167 INT104906 Negative_regulation of Alpl 5 0.31 1.72 0.21 62.16
168 INT104905 Localization of Alpl 2 0.08 1.08 0.13 62.16
169 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 61.68
170 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 61.68
171 INT118124 Binding of USE1 24 0.16 16.64 5.44 61.04
172 INT22715 Positive_regulation of Gene_expression of Pth 29 0.64 22.53 2.31 60.72
173 INT6514 Positive_regulation of Gene_expression of PTH 28 0.67 30.28 1.37 58.88
174 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 58.12
175 INT173576 Negative_regulation of FDPS 25 0.57 8.42 1.91 57.68
176 INT170507 Localization of Tmie 27 0.43 6.25 1.31 57.08
177 INT170503 Positive_regulation of Localization of Tmie 11 0.29 3.27 0.61 57.08
178 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 56.40
179 INT10070 Negative_regulation of Fshb 13 0.42 3.48 2.5 56.40
180 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 56.40
181 INT2160 Negative_regulation of Negative_regulation of LH 22 0.58 4.58 11.53 56.40
182 INT338123 Phosphorylation of GET4 1 0.35 0.22 0 56.24
183 INT242153 Negative_regulation of Wnt2 19 0.49 11.87 1.37 56.08
184 INT119729 Binding of Tnfsf11 31 0.35 24.02 7.45 55.84
185 INT14724 Negative_regulation of CYP19A1 233 0.59 96.56 18.26 55.80
186 INT171959 Binding of Tnfrsf11a 15 0.34 11.03 3.02 55.60
187 INT1893 Localization of Gh 1041 0.79 340.23 256.58 55.44
188 INT5865 Positive_regulation of Localization of Gh 282 0.69 84.86 93.5 55.44
189 INT1498 Gene_expression of Gh 521 0.75 220.84 81.16 55.44
190 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 55.20
191 INT187090 Positive_regulation of Localization of Col7a1 4 0.07 3.16 0.51 55.20
192 INT134966 Localization of Col7a1 23 0.42 16.4 5.24 54.96
193 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 54.48
194 INT32677 Positive_regulation of Npepo 8 0.49 3.1 1.92 52.64
195 INT8413 Gene_expression of Ptgs1 248 0.78 110.17 108.58 52.00
196 INT48240 Binding of Ngf 46 0.46 23.51 24.42 51.80
197 INT11157 Binding of EGF 88 0.48 53.73 21.25 51.80
198 INT134694 Binding of CYP27A1 10 0.47 5.61 3.56 51.36
199 INT3343 Regulation of PTH 24 0.62 11.18 1.62 50.92
200 INT224424 Regulation of TNFRSF11B 12 0.61 6.29 1.61 50.64
Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox