D:Pressure And Volume Under Development

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Latest revision as of 19:12, 5 October 2012

pChart

Disease Term
Synonyms Aggravated Hypertension, Aggravation Of Hypertension, ANASARCA, Angiedema Of The Face, Angiedema Of The Upper Airways, Angio Edema, Angio Oedema, Angioedema, Angioedema Of The Face, ANGIOEDEMA OF THE UPPER AIRWAYS, Angiooedema
Documents 24473
Hot Single Events 200
Hot Interactions 200

[edit] Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Pressure And Volume Under Development. They are ordered first by their relevance to Pressure And Volume Under Development and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT172674 Ptpn6 Negative_regulation of Gene_expression of Plat 1 0.02 1.3 0.16 100.00
2 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23 100.00
3 INT332699 Binding of KNG1 and TRGC1 1 0.16 3.37 0.75 100.00
4 INT270995 Binding of CYSLTR2 and OR6B1 1 0.01 2.14 0.15 100.00
5 INT168457 Sult1a1 Positive_regulation of Cat 1 0.15 1.56 0.78 100.00
6 INT95546 KNG1 Positive_regulation of Ptgir 1 0.02 0.93 0.64 100.00
7 INT132731 Positive_regulation of Binding of Il1b and Il6 1 0.46 1.2 0.61 100.00
8 INT168460 Sult1a1 Negative_regulation of Gene_expression of Ifih1 1 0.02 0.96 0.41 100.00
9 INT292621 Binding of IL6 and Gpt 1 0.01 3.88 0.24 100.00
10 INT267625 Binding of KNG1 and Klk1 2 0.21 2.23 0.61 100.00
11 INT58633 Negative_regulation of Il1f5 Negative_regulation of Mpo 1 0.15 0.98 0.48 100.00
12 INT168461 Sult1a1 Positive_regulation of Gpx1 1 0.12 0.83 0.39 100.00
13 INT58634 Negative_regulation of Il1 Negative_regulation of Mpo 1 0.20 0.98 0.47 100.00
14 INT290269 KNG1 Positive_regulation of Binding of MID1 1 0.02 1.06 0.41 100.00
15 INT290270 KNG1 Positive_regulation of MID1 1 0.02 1.06 0.41 100.00
16 INT162319 Positive_regulation of F2rl1 Positive_regulation of Il1b 1 0.46 1.6 1.04 100.00
17 INT292615 Binding of IL6 and SLC17A5 1 0.01 1.8 0.16 100.00
18 INT150632 Ea1 Negative_regulation of Mpo 1 0.17 1.55 2.9 100.00
19 INT110671 Binding of Cnr1 and Alox5 1 0.07 0.2 1.13 100.00
20 INT110669 Binding of Alox5 and Trpv1 1 0.07 0.2 1.13 100.00
21 INT102324 Nme3 Negative_regulation of Pla2g1b 1 0.05 1.07 0.35 100.00
22 INT215543 Negative_regulation of Trim33 Negative_regulation of Gopc 1 0.15 0.35 0.48 100.00
23 INT278690 LEF1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83 100.00
24 INT278696 MTX1 Negative_regulation of Gene_expression of IK 1 0.00 0.66 0.83 100.00
25 INT302821 Mdk Negative_regulation of Il1 1 0.02 0.91 0.38 100.00
26 INT116853 Chdh Regulation of Positive_regulation of Agt 1 0.11 0.19 0.28 100.00
27 INT63521 Negative_regulation of Ptgs2 Negative_regulation of Gene_expression of Fos 1 0.66 0.1 0.12 100.00
28 INT323071 Binding of RT1-DOa and Ppara 1 0.13 0.74 0.09 100.00
29 INT149185 Regulation of H2-Ab1 Regulation of Trpv1 1 0.34 0.52 0.08 100.00
30 INT149184 H2-Ab1 Regulation of Trpv1 1 0.34 0.52 0.08 100.00
31 INT352496 AVP Regulation of Gene_expression of CRS 1 0.27 2.47 0.59 99.84
32 INT168435 Positive_regulation of Binding of GLRX and Gpx1 1 0.05 0.91 0.42 99.82
33 INT332700 Binding of F12 and KNG1 1 0.15 1.05 0.21 99.82
34 INT212660 Nr3c1 Regulation of KCNA1 1 0.00 1.25 1.57 99.76
35 INT191220 Cotl1 Positive_regulation of Edn1 1 0.19 0.69 0 99.76
36 INT132732 Binding of Il1b and Il6 1 0.35 0.6 0.3 99.76
37 INT171902 TNF Positive_regulation of Il1f5 1 0.05 0.52 0.14 99.56
38 INT171904 TNF Positive_regulation of Il1 1 0.35 0.52 0.14 99.56
39 INT317071 KCNC4 Regulation of SCNN1G 1 0.03 0.17 0.13 99.56
40 INT168434 Binding of GLRX and Gpx1 1 0.04 0.9 0.42 99.52
41 INT158391 Oxt Positive_regulation of Localization of Nppa 2 0.27 0.64 0.03 99.50
42 INT168454 Sult1a1 Negative_regulation of Ifih1 1 0.02 0.89 0.39 99.40
43 INT24967 Olr567 Regulation of Localization of Syt17 1 0.11 0.62 0.71 99.40
44 INT354522 Binding of HBG2 and Wipi1 1 0.00 2.64 0.87 99.34
45 INT241780 Binding of AVP and TRGV9 1 0.12 2.41 0.35 99.32
46 INT241778 AVP Positive_regulation of AVPR1A 1 0.10 1.32 0 99.24
47 INT212658 KCNA1 Positive_regulation of Cort 1 0.00 2.58 3.36 99.08
48 INT191219 Edn1 Positive_regulation of Amigo2 1 0.06 1.26 0.07 99.08
49 INT181618 NOS3 Positive_regulation of INS 1 0.02 0.59 0.03 98.96
50 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23 98.92
51 INT332707 Binding of TRGC1 and Klk1 1 0.32 1.64 0.36 98.82
52 INT161653 Gsr Regulation of Gene_expression of Ifih1 1 0.04 1.05 0.46 98.76
53 INT226786 Scl1 Positive_regulation of Lbp 1 0.04 1.68 0.07 98.72
54 INT226787 Trglyd Positive_regulation of Lbp 1 0.04 1.67 0.07 98.72
55 INT177714 Binding of GALNT3 and REN 1 0.01 2.36 0.12 98.68
56 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23 98.68
57 INT124088 Rab38 Negative_regulation of Mapk14 1 0.00 0.89 0.42 98.56
58 INT228494 Binding of Ncoa5 and Rela 1 0.00 1.58 0.72 98.56
59 INT66907 Il1b Positive_regulation of Localization of Oxt 2 0.78 0.18 1.12 98.48
60 INT66908 Il1b Positive_regulation of Localization of Avp 1 0.36 0.49 0.31 98.48
61 INT34762 Binding of PTGIR and REN 1 0.30 0.24 0 98.40
62 INT34763 Binding of AGT and PTGER2 1 0.04 0.24 0 98.40
63 INT34764 Binding of AGT and PTGIR 1 0.08 0.24 0 98.40
64 INT34765 Binding of PTGER2 and REN 1 0.16 0.24 0 98.40
65 INT34766 Binding of PTGER2 and PTGIR 1 0.14 0.24 0 98.40
66 INT288911 AGT Positive_regulation of CYBB 3 0.07 2.96 0.28 98.34
67 INT21331 Binding of Adarb1 and Gm5195 1 0.00 0.26 1.08 98.28
68 INT21329 Binding of Man2a2 and Gm5195 1 0.00 0.26 1.06 98.28
69 INT21332 Binding of Drd2 and Gm5195 1 0.01 0.26 1 98.28
70 INT21330 Binding of Htr1f and Gm5195 1 0.00 0.26 0.99 98.28
71 INT189300 Atp6v1e1 Regulation of Gene_expression of Prl 1 0.03 0.29 0.39 98.16
72 INT250803 Binding of SARS and MBL3P 1 0.09 1.7 0.04 97.96
73 INT168455 Sult1a1 Negative_regulation of Nos2 1 0.08 1.99 0.79 97.84
74 INT168456 Arr3 Positive_regulation of Nos2 1 0.21 1.98 0.79 97.84
75 INT161652 Gsr Regulation of Gene_expression of Tnf 1 0.17 0.98 0.46 97.84
76 INT130335 Binding of Mc4r and Nr3c2 1 0.06 1.87 0.5 97.76
77 INT168458 Sult1a1 Negative_regulation of Tnf 1 0.09 1 0.4 97.76
78 INT168463 Sult1a1 Negative_regulation of TNF 1 0.01 1 0.4 97.76
79 INT168462 Sult1a1 Negative_regulation of Arr3 Positive_regulation of Nos2 1 0.05 1 0.4 97.60
80 INT192109 PAH Positive_regulation of Binding of COL7A1 1 0.04 1.45 0.2 97.60
81 INT241251 Pkd2 Negative_regulation of Gene_expression of Gopc 1 0.12 0.24 0.03 97.52
82 INT88774 Binding of AGT and Agtrap 2 0.01 2.13 0.03 97.48
83 INT161662 Gsr Regulation of Gene_expression of TNF 1 0.01 0.93 0.46 97.40
84 INT58588 IFNG Positive_regulation of ARHGAP4 1 0.31 1.22 0.19 97.36
85 INT105690 Ngf Positive_regulation of TRPV1 1 0.05 1.43 1.08 97.22
86 INT284785 Gch1 Regulation of Bh4p 1 0.00 1.48 1.54 97.16
87 INT269503 Lta Regulation of Nos1 1 0.44 1.3 0 97.00
88 INT285569 TNF Negative_regulation of Gene_expression of Il6 1 0.03 2.83 1.46 96.96
89 INT195443 MMP2 Positive_regulation of Protein_catabolism of Mmp9 1 0.15 0.95 0.14 96.88
90 INT233929 PPARA Negative_regulation of ras 1 0.02 2.39 0.22 96.84
91 INT1226 Fabp6 Negative_regulation of Snai1 1 0.03 0.49 0.07 96.76
92 INT180718 Binding of SARS and ACE2 3 0.12 7.76 0.25 96.68
93 INT161655 Gsr Regulation of Gene_expression of Il1b 1 0.20 1.84 0.9 96.64
94 INT161654 Gsr Regulation of Gpx1 1 0.14 0.85 0.42 96.64
95 INT216545 Gene_expression of Cftr Negative_regulation of Kcnma1 1 0.00 0.59 0.06 96.48
96 INT186566 Hpcl1 Positive_regulation of Fos 1 0.17 0.38 4.49 96.48
97 INT186540 Binding of Cort and Hpse 1 0.05 0.92 0.08 96.48
98 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18 96.44
99 INT193219 Binding of LTC4S and CYSLTR2 2 0.28 2.2 0.44 96.28
100 INT354985 Cacna1a Regulation of Nos2 1 0.01 0.73 0.34 96.28
101 INT311733 Plat Regulation of Protein_catabolism of Orai1 1 0.28 0.71 0.13 96.16
102 INT311727 Plat Regulation of Protein_catabolism of Col17a1 1 0.31 0.71 0.13 96.16
103 INT311737 Plat Regulation of Positive_regulation of Fcgr2b 1 0.31 0.71 0.13 96.16
104 INT311731 Plat Regulation of Protein_catabolism of Pik3cd 1 0.31 0.71 0.13 96.16
105 INT119457 Binding of Pts and Del(7)Tyr<c-23DVT>-p 1 0.01 1.34 0.1 96.04
106 INT301083 Binding of BCS1L and MYH7 1 0.36 1.53 0.19 96.00
107 INT61976 TBP Negative_regulation of Tnf 1 0.24 1.17 0.17 95.92
108 INT354982 Cacna1a Regulation of Tnf 1 0.00 0.73 0.34 95.92
109 INT292082 MIR1200 Negative_regulation of KDR 1 0.00 1.24 0 95.92
110 INT292091 MIR1200 Negative_regulation of PDGFRB 1 0.01 1.24 0 95.92
111 INT313481 Binding of Cd3e and Epcam 1 0.19 0.81 0 95.60
112 INT267684 Binding of INS and ARID1B 3 0.10 6.08 0.09 95.56
113 INT241246 Pkd2 Negative_regulation of Gene_expression of Trpv4 1 0.48 0.47 0.07 95.44
114 INT271003 Binding of TBXA2R and Aia1 1 0.01 1.81 0.14 95.40
115 INT301289 Positive_regulation of Clec5a Positive_regulation of Gene_expression of Atp6v0d2 1 0.02 1.01 0.28 95.08
116 INT354986 Cacna1a Regulation of Localization of Mpo 1 0.01 1.15 0.49 94.84
117 INT148922 Pdia4 Negative_regulation of Tnf 1 0.09 1.01 0.56 94.76
118 INT133745 Vcan Regulation of TNC 1 0.11 0.71 0.46 94.76
119 INT1066 Gm5720 Positive_regulation of MBD2 1 0.00 0.73 0.42 94.48
120 INT181646 interleukin-17 Positive_regulation of ISYNA1 1 0.01 0.26 0.2 94.48
121 INT181617 IL17A Positive_regulation of ISYNA1 1 0.01 0.27 0.2 94.48
122 INT319963 Binding of IGFALS and Vcan 1 0.03 2.99 0.13 93.88
123 INT207466 LGALS3 Positive_regulation of Gene_expression of ADAMTS5 1 0.15 0.88 0.51 93.88
124 INT207461 LGALS3 Positive_regulation of Gene_expression of MMP3 1 0.18 0.48 0.21 93.88
125 INT230532 LILRB1 Positive_regulation of Gene_expression of Mmp2 1 0.14 1.04 0.5 93.84
126 INT310302 Tlr4 Regulation of Positive_regulation of Serpina10 1 0.01 0.53 0.18 93.76
127 INT164012 Regulation of Binding of CNBP and Chdh 1 0.06 0.99 0.13 93.60
128 INT164011 Binding of CNBP and Chdh 1 0.05 0.99 0.13 93.60
129 INT51275 IGF1 Negative_regulation of INS 2 0.35 0.98 0.29 93.56
130 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17 93.40
131 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17 93.40
132 INT148436 Binding of Gdnf and Ngf 1 0.35 1.14 0.4 93.40
133 INT148438 Binding of Bdnf and Ntf3 1 0.33 1.14 0.4 93.40
134 INT166222 Gene_expression of Fos Positive_regulation of Col6a6 1 0.01 0.57 0.77 93.36
135 INT141881 Binding of MECOM and Tnfrsf1a 1 0.00 1.17 0.13 93.28
136 INT87750 IGFBP3 Negative_regulation of INS 1 0.11 0.86 0.23 93.24
137 INT294091 Binding of PGF and VEGFA 1 0.02 1.21 0 93.12
138 INT132730 Plat Positive_regulation of Il6 1 0.08 0.76 0.41 93.04
139 INT132729 Plat Positive_regulation of Il1b 1 0.09 0.76 0.41 93.04
140 INT340420 Hmmr Regulation of P2rx7 1 0.01 1.12 0.08 92.96
141 INT340424 Hmmr Regulation of Cxcl2 1 0.01 1.12 0.08 92.76
142 INT340425 Hmmr Regulation of Ccl2 1 0.01 1.12 0.08 92.76
143 INT220289 MARS Regulation of CEBPZ 1 0.02 0.93 0.11 92.72
144 INT289659 Tnfrsf1b Negative_regulation of Mcpt3 1 0.02 0.82 1.13 92.64
145 INT260423 IFNA1 Positive_regulation of Gene_expression of VEGFA 1 0.01 1.28 0.26 92.64
146 INT351915 P2ry1 Regulation of Gfm1 1 0.01 0.86 0.03 92.60
147 INT351914 P2ry1 Regulation of Gene_expression of Gfm1 1 0.01 0.86 0.03 92.60
148 INT113113 COX5A Regulation of Gene_expression of MRXS5 1 0.10 0.9 0.45 92.52
149 INT182051 Il18 Positive_regulation of Il1 1 0.18 0.77 0.38 92.40
150 INT173430 Binding of FLT4 and VEGFA 10 0.25 9.38 0.19 92.24
151 INT328500 Sumo1 Positive_regulation of Negative_regulation of Cebpz 1 0.11 1.06 0.29 92.16
152 INT191214 Cotl1 Positive_regulation of Prkcg 1 0.10 1.35 0.04 92.10
153 INT313741 Negative_regulation of NOS1 Positive_regulation of Sdcbp 1 0.00 0.78 0.09 91.92
154 INT220188 EC Positive_regulation of CADM1 1 0.00 1.72 0.44 91.84
155 INT222438 Nps Positive_regulation of Localization of Pomc 1 0.01 0.66 0 91.84
156 INT222413 Nps Positive_regulation of Localization of Crh 1 0.03 0.66 0 91.84
157 INT230533 LILRB1 Positive_regulation of Positive_regulation of Mmp9 1 0.20 1.03 0.5 91.76
158 INT66909 Il1b Regulation of Localization of Avp 1 0.32 0.09 0.15 91.72
159 INT154538 SF Regulation of Gene_expression of PPY 1 0.11 1 0.14 91.64
160 INT191217 Cotl1 Positive_regulation of Amigo2 1 0.02 0.61 0.03 91.44
161 INT241776 Binding of AVP and Positive_regulation of ADCY1 1 0.06 0.54 0.32 91.40
162 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24 91.36
163 INT221249 Hspa9 Negative_regulation of Gene_expression of Ros1 1 0.01 0.91 0 91.12
164 INT221241 Sf3a2 Negative_regulation of Gene_expression of Ros1 1 0.00 0.91 0 91.12
165 INT106630 Binding of GRK5 and PRKCA 1 0.16 0.82 0.19 91.04
166 INT331768 Binding of Arg1 and NOSTRIN 1 0.01 0.6 0.17 90.96
167 INT331766 Binding of Arg1 and Nos2 1 0.17 0.6 0.17 90.96
168 INT338039 F2 Positive_regulation of Positive_regulation of Prkca 1 0.04 0.52 0.27 90.92
169 INT151460 Olr1745 Positive_regulation of Il4 1 0.04 0.83 0.59 90.76
170 INT151459 Olr1745 Negative_regulation of Gene_expression of Nos2 1 0.04 0.82 0.57 90.76
171 INT151461 Olr1745 Negative_regulation of Gene_expression of Il6 1 0.03 0.81 0.57 90.76
172 INT191493 Binding of AGTR1 and NLRP3 2 0.03 2.35 0.39 90.56
173 INT182499 Binding of AGTR1 and AGTR2 3 0.20 2.79 0.28 90.56
174 INT158267 Olr1745 Negative_regulation of Alox5 1 0.05 0.94 0.43 90.56
175 INT285561 Il23a Positive_regulation of Gene_expression of Il22 2 0.06 2.45 0.93 90.56
176 INT158266 Olr1745 Negative_regulation of Ptgs1 1 0.01 0.52 0.27 90.56
177 INT158265 Olr1745 Negative_regulation of Gene_expression of Ltb 1 0.01 0.52 0.27 90.56
178 INT206960 Lipg Regulation of Tnf 1 0.02 0.85 0.51 90.52
179 INT206961 Lipg Regulation of Ptger2 1 0.01 0.85 0.51 90.52
180 INT206958 Lipg Regulation of Gene_expression of Ptger2 1 0.01 0.85 0.51 90.52
181 INT262255 Binding of APC and F2R 1 0.05 3 0.1 90.40
182 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 90.40
183 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29 90.32
184 INT233907 Positive_regulation of Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08 90.28
185 INT28992 Tmpo Positive_regulation of Pomc 1 0.36 3.18 1.41 90.20
186 INT28991 Tmpo Positive_regulation of Gene_expression of Pomc 1 0.34 0.82 0.37 90.20
187 INT133163 Nos2 Regulation of Tnf 1 0.36 0.97 0.22 90.00
188 INT133166 ELANE Regulation of Tnf 1 0.01 0.98 0.22 90.00
189 INT133164 Ptgs2 Regulation of Tnf 1 0.14 0.98 0.22 90.00
190 INT233906 Binding of AGTR2 and NLRP3 1 0.01 1.09 0.08 89.96
191 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3 89.76
192 INT180715 Binding of SARS and CLEC4M 2 0.12 2.92 0.11 89.68
193 INT300192 Gene_expression of APOA1 Positive_regulation of HSD11B1 1 0.16 1.08 0.08 89.56
194 INT241253 Gene_expression of Trpv4 Positive_regulation of Gene_expression of Pkd2 1 0.52 0.29 0.03 89.52
195 INT196640 PTGER2 Negative_regulation of DNAH8 1 0.00 0.46 0.08 89.52
196 INT336341 Binding of RTCA and ELOVL1 1 0.02 2.15 0.07 89.52
197 INT191218 Edn1 Regulation of Positive_regulation of Prkcg 1 0.14 0.32 0 89.36
198 INT342164 Binding of Csf2 and Nkx2-1 1 0.01 0.52 0.26 89.36
199 INT342163 Nkx2-1 Regulation of Gene_expression of Aqp1 1 0.06 0.51 0.2 89.36
200 INT167466 Ccdc80 Negative_regulation of Tnf 1 0.01 0.76 0.88 89.20

[edit] Single Events

The table below shows the top 200 pain related interactions that have been reported for Pressure And Volume Under Development. They are ordered first by their pain relevance and then by number of times they were reported in Pressure And Volume Under Development. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
2 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
3 INT6056 Negative_regulation of Gene_expression of Fos 601 0.59 193.05 386.84 100.00
4 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 100.00
5 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 100.00
6 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 100.00
7 INT3657 Gene_expression of Ins1 514 0.78 321.69 75.76 100.00
8 INT16359 Positive_regulation of Gene_expression of AGT 30 0.49 28.27 6.14 100.00
9 INT156672 Localization of SERPING1 10 0.74 12.15 1.25 100.00
10 INT6993 Negative_regulation of Mpo 72 0.59 61.83 19.51 100.00
11 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 100.00
12 INT2431 Positive_regulation of Mpo 275 0.70 211.99 78.47 100.00
13 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 100.00
14 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 100.00
15 INT613 Gene_expression of Alb 268 0.78 149.84 42.78 100.00
16 INT72923 Positive_regulation of MCRS1 72 0.50 99.19 30.36 100.00
17 INT46 Localization of Ren 233 0.81 46.15 62.44 100.00
18 INT2824 Positive_regulation of HTN1 10 0.40 10.41 1.4 100.00
19 INT6852 Localization of TNF 883 0.81 705.95 270.84 100.00
20 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 100.00
21 INT183075 Binding of Hypt 7 0.22 7.47 0.38 100.00
22 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 100.00
23 INT2429 Negative_regulation of Mpo 128 0.59 93.76 39.57 100.00
24 INT6726 Positive_regulation of Edn1 118 0.70 65.96 24.07 100.00
25 INT13353 Positive_regulation of Tnf 332 0.70 248.75 148.1 100.00
26 INT149145 Positive_regulation of Gene_expression of Ang2 4 0.34 27.89 0.78 100.00
27 INT1033 Positive_regulation of Ca2 507 0.68 131.76 147.64 100.00
28 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 100.00
29 INT49439 Gene_expression of Cpox 508 0.73 326.97 130.17 100.00
30 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 100.00
31 INT390 Positive_regulation of Agt 170 0.70 61.47 36.08 100.00
32 INT8243 Positive_regulation of Il6 451 0.70 358.24 119.28 100.00
33 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 100.00
34 INT183080 Gene_expression of Hypt 5 0.14 7.53 0.85 100.00
35 INT3656 Positive_regulation of Gene_expression of Ins1 74 0.54 44.94 17.36 100.00
36 INT2451 Positive_regulation of Avp 355 0.70 102.66 147.69 100.00
37 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 100.00
38 INT724 Negative_regulation of Alb 151 0.59 93.57 29.65 100.00
39 INT6110 Negative_regulation of Gene_expression of Ins1 83 0.56 60.59 16.07 100.00
40 INT44003 Gene_expression of F3 40 0.75 27.92 8.29 100.00
41 INT11829 Negative_regulation of Odc1 54 0.59 7.03 23.03 100.00
42 INT117222 Positive_regulation of Gene_expression of TLR4 80 0.70 51.6 12.9 100.00
43 INT48075 Positive_regulation of Il1b 71 0.67 48.63 40.48 100.00
44 INT3252 Negative_regulation of INS 428 0.59 271.65 39.52 100.00
45 INT124605 Gene_expression of Ifih1 16 0.57 7.36 5.33 100.00
46 INT1177 Positive_regulation of Positive_regulation of Ren 16 0.70 6.11 3 100.00
47 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 100.00
48 INT132335 Gene_expression of KCNA1 36 0.77 18.31 13.36 100.00
49 INT15850 Positive_regulation of Trim25 4 0.43 5.64 2.52 100.00
50 INT109770 Gene_expression of ATP5J 6 0.48 1.73 0 100.00
51 INT1497 Negative_regulation of Gh 415 0.59 192.95 74.71 100.00
52 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 100.00
53 INT886 Gene_expression of Pomc 676 0.78 129.87 295.98 100.00
54 INT327416 Localization of Apeh 1 0.07 2.19 0.14 100.00
55 INT313916 Negative_regulation of Protein_catabolism of ALB 1 0.18 2.86 0 100.00
56 INT9110 Binding of PAH 32 0.41 42.1 3.1 100.00
57 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 100.00
58 INT959 Regulation of ATRX 5 0.47 5.04 0.89 100.00
59 INT163969 Positive_regulation of Hypt 6 0.41 6.24 0.49 100.00
60 INT5617 Localization of Nppa 266 0.81 83.51 83.89 100.00
61 INT18773 Localization of ALB 117 0.80 69.18 13.8 100.00
62 INT179225 Positive_regulation of AMIGO2 10 0.43 9.62 2.05 100.00
63 INT10056 Positive_regulation of Fabp6 77 0.59 36.99 16.8 100.00
64 INT104668 Negative_regulation of Plat 27 0.49 17.18 4.83 100.00
65 INT77246 Positive_regulation of WNK1 5 0.10 4.24 1.13 100.00
66 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78 100.00
67 INT127458 Positive_regulation of PAH 24 0.58 27.25 2.53 100.00
68 INT4824 Positive_regulation of Tacr1 169 0.70 66.1 123.46 100.00
69 INT22939 Gene_expression of Csf2 164 0.78 85.1 32.22 100.00
70 INT66532 Positive_regulation of Pnoc 46 0.70 14.99 41.39 100.00
71 INT1921 Gene_expression of CEACAM7 47 0.78 43.23 2.53 100.00
72 INT183079 Negative_regulation of Gene_expression of Hypt 1 0.04 1.09 0 100.00
73 INT170646 Negative_regulation of Fig4 213 0.37 81.29 46.92 100.00
74 INT5650 Gene_expression of Mpo 117 0.77 80.27 26.42 100.00
75 INT183082 Transcription of Hypt 1 0.07 1.02 0.03 100.00
76 INT19158 Gene_expression of PAH 35 0.65 35.81 3.88 100.00
77 INT183077 Negative_regulation of Hypt 1 0.04 1.69 0 100.00
78 INT7475 Positive_regulation of Hdl1 138 0.67 175.81 15.05 100.00
79 INT183076 Regulation of Hypt 2 0.16 1.46 0 100.00
80 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 100.00
81 INT86646 Positive_regulation of SCN10A 71 0.69 50.61 13.24 100.00
82 INT36962 Positive_regulation of vs 9 0.28 5.57 1.92 100.00
83 INT9650 Gene_expression of LPA 141 0.75 104.57 29 100.00
84 INT10706 Regulation of Il6 150 0.62 93.23 62.34 100.00
85 INT3579 Localization of Oxt 555 0.81 43.35 292.44 100.00
86 INT186259 Gene_expression of NR5A1 2 0.64 2.19 0.05 100.00
87 INT246703 Binding of Bsg 1 0.02 2.49 0.1 100.00
88 INT158542 Gene_expression of HTN1 10 0.75 10.69 1.07 100.00
89 INT158541 Positive_regulation of Gene_expression of HTN1 3 0.40 5.88 0.97 100.00
90 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 100.00
91 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7 100.00
92 INT284491 Binding of METTL3 1 0.01 0.78 0.08 100.00
93 INT328285 Negative_regulation of Localization of SERPING1 1 0.37 0.95 0 100.00
94 INT182145 Regulation of Protein_catabolism of Slco1c1 2 0.18 2.5 0.36 100.00
95 INT58302 Regulation of Mpo 13 0.62 11.14 3.04 100.00
96 INT6129 Positive_regulation of Localization of AVP 63 0.70 30.44 16.64 100.00
97 INT84320 Negative_regulation of Positive_regulation of Mpo 11 0.46 8 3.09 100.00
98 INT15213 Positive_regulation of Htas2 9 0.67 3.86 5.14 100.00
99 INT2660 Negative_regulation of Fabp6 58 0.49 33.74 18.27 100.00
100 INT183078 Protein_catabolism of Hypt 1 0.09 0.75 0 100.00
101 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
102 INT116736 Positive_regulation of Mif 40 0.70 31.93 15.37 100.00
103 INT12001 Regulation of Ngf 97 0.62 54.64 76.25 100.00
104 INT179219 Regulation of AMIGO2 1 0.09 3.88 1.3 100.00
105 INT83611 Negative_regulation of Gene_expression of Cpox 55 0.29 31.09 11.5 100.00
106 INT100372 Gene_expression of Flt1 47 0.71 24.33 4.09 100.00
107 INT100373 Negative_regulation of Gene_expression of Flt1 11 0.53 10 1.37 100.00
108 INT105044 Negative_regulation of Flt1 4 0.39 2.99 0.15 100.00
109 INT21148 Regulation of Positive_regulation of EDDM3B 1 0.00 0.73 0.25 100.00
110 INT18736 Gene_expression of Ptpn6 19 0.59 4.44 8.06 100.00
111 INT2149 Positive_regulation of Oxt 181 0.70 24.8 85.43 100.00
112 INT121801 Binding of Aip 18 0.36 24.1 5.26 100.00
113 INT168432 Negative_regulation of Positive_regulation of Gpx1 4 0.40 2.89 0.75 100.00
114 INT158540 Negative_regulation of HTN1 4 0.34 7.25 1.22 100.00
115 INT15481 Positive_regulation of asa 13 0.39 6.12 8.24 100.00
116 INT17996 Binding of Crp 40 0.37 31.4 7.8 100.00
117 INT75105 Gene_expression of SLC15A4 3 0.19 3.33 0.74 100.00
118 INT68279 Positive_regulation of Gene_expression of Csf2 30 0.67 16.31 6.88 100.00
119 INT293903 Localization of HTN1 2 0.10 0.98 0.1 100.00
120 INT81664 Positive_regulation of Gene_expression of Pnoc 12 0.68 2.51 9.75 100.00
121 INT117476 Negative_regulation of Gene_expression of Mpo 10 0.43 8.25 3.33 100.00
122 INT54563 Negative_regulation of Positive_regulation of PIF1 1 0.42 0.86 0.23 100.00
123 INT36961 Negative_regulation of Positive_regulation of vs 1 0.24 1.02 0.35 100.00
124 INT4498 Gene_expression of F2 83 0.65 57.4 10.8 100.00
125 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 100.00
126 INT7885 Positive_regulation of Localization of Oxt 160 0.70 14.36 87.7 100.00
127 INT109763 Positive_regulation of Gene_expression of Cct6a-ps6 1 0.03 0.83 0 100.00
128 INT5513 Negative_regulation of Pomc 295 0.59 60.9 158.63 100.00
129 INT2330 Regulation of CB 78 0.10 20.46 32.6 100.00
130 INT19949 Regulation of Positive_regulation of Fos 36 0.60 6.11 22.05 100.00
131 INT59900 Binding of MATN3 13 0.42 17.19 3.59 100.00
132 INT160828 Regulation of Gene_expression of Ros1 29 0.21 13.97 3.75 100.00
133 INT111514 Positive_regulation of Gene_expression of Mpo 20 0.49 15.13 3.88 100.00
134 INT109767 Positive_regulation of Gene_expression of ATP5J 1 0.31 0.67 0 100.00
135 INT162 Regulation of Prl 794 0.62 165.01 322.24 100.00
136 INT345424 Phosphorylation of PAH 1 0.05 1.55 0.11 100.00
137 INT132334 Negative_regulation of Gene_expression of KCNA1 4 0.43 1.52 1.14 100.00
138 INT79227 Negative_regulation of Gene_expression of Icam1 45 0.59 41.65 14.97 100.00
139 INT201196 Negative_regulation of Gene_expression of PAH 2 0.30 3.11 0.19 100.00
140 INT2275 Negative_regulation of Localization of Ins1 183 0.59 51.02 44.94 100.00
141 INT70304 Negative_regulation of Il5 6 0.35 3.64 1.35 100.00
142 INT76401 Localization of Nppc 2 0.54 1.09 0.24 100.00
143 INT76404 Localization of Cnp 4 0.68 0.87 0.68 100.00
144 INT93014 Positive_regulation of Positive_regulation of Il5 1 0.41 1.07 0.09 100.00
145 INT66753 Negative_regulation of Positive_regulation of Tnf 45 0.59 35.28 22.33 100.00
146 INT62253 Regulation of Gene_expression of FLII 3 0.60 0.98 1.73 100.00
147 INT48438 Gene_expression of Defb22 5 0.09 1.96 2.34 100.00
148 INT2453 Positive_regulation of Apoa2 20 0.54 3.49 4.08 100.00
149 INT209783 Binding of SLC15A4 2 0.04 1.25 0.3 100.00
150 INT104570 Localization of Aqp1 8 0.77 5.83 3.51 100.00
151 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 100.00
152 INT4342 Localization of ALPP 27 0.69 15.19 5.32 100.00
153 INT200217 Localization of PAH 10 0.36 15.51 2.46 100.00
154 INT8532 Regulation of Transcription of PDYN 10 0.44 4.97 6.95 100.00
155 INT104539 Regulation of Positive_regulation of FOXG1 1 0.38 0.2 0.19 100.00
156 INT17035 Positive_regulation of TFPI 55 0.61 34.88 14.18 100.00
157 INT162374 Negative_regulation of Positive_regulation of ASAP1 2 0.12 0.71 0.21 100.00
158 INT92572 Gene_expression of Mapk7 17 0.78 3.71 4.76 100.00
159 INT162372 Positive_regulation of SFTPD 15 0.67 11.8 3.21 100.00
160 INT29674 Gene_expression of Ada 16 0.78 4.59 5.69 100.00
161 INT130033 Regulation of Localization of RETNLB 2 0.00 2.27 1.52 100.00
162 INT203640 Regulation of MR1 7 0.34 3.8 1.26 100.00
163 INT183081 Phosphorylation of Hypt 1 0.06 0.71 0 100.00
164 INT82079 Positive_regulation of Lep 79 0.70 40 11.07 100.00
165 INT9012 Localization of Vip 283 0.81 31.71 106.16 100.00
166 INT1486 Negative_regulation of Cpe 85 0.59 28.78 54.08 100.00
167 INT8188 Positive_regulation of Adrb3 27 0.68 7.32 10.44 100.00
168 INT5854 Regulation of Gene_expression of Penk 22 0.61 6.91 10.03 100.00
169 INT8529 Regulation of Transcription of Penk 8 0.39 1.26 5.89 100.00
170 INT24332 Regulation of Hdl1 28 0.45 45.45 4.26 100.00
171 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 100.00
172 INT141002 Negative_regulation of Fcer2a 15 0.12 7.17 1.88 100.00
173 INT55113 Positive_regulation of Gene_expression of CRS 5 0.29 4.92 1.25 100.00
174 INT17330 Binding of FOXG1 3 0.33 0.23 0.83 100.00
175 INT32618 Regulation of Positive_regulation of Agt 2 0.43 0.42 0.52 100.00
176 INT147098 Gene_expression of ECA1 4 0.15 2.83 0.48 100.00
177 INT116735 Positive_regulation of Positive_regulation of Mif 1 0.70 0.61 0.38 100.00
178 INT240681 Positive_regulation of AVPR2 3 0.41 0.87 0.29 100.00
179 INT14735 Positive_regulation of COL6A2 3 0.42 3.13 0.22 100.00
180 INT35232 Regulation of Positive_regulation of Apoa2 1 0.48 0.18 0.05 100.00
181 INT231889 Regulation of Positive_regulation of IAPP 1 0.26 0.55 0 100.00
182 INT156130 Binding of SERPING1 29 0.42 26.16 2.52 99.98
183 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 99.98
184 INT61223 Positive_regulation of Negative_regulation of ACE 6 0.49 5.92 1.37 99.98
185 INT85937 Protein_catabolism of ALB 6 0.86 4.31 0.38 99.98
186 INT326469 Positive_regulation of Negative_regulation of AGTR2 1 0.09 2.96 0.16 99.98
187 INT385 Gene_expression of Agt 182 0.78 63.62 37.91 99.98
188 INT35744 Binding of MAOB 13 0.46 7.52 4.26 99.98
189 INT36960 Gene_expression of vs 33 0.43 20.77 6.97 99.98
190 INT170758 Positive_regulation of Localization of Cftr 2 0.50 2.4 0.35 99.98
191 INT546 Binding of ALB 311 0.48 85.98 60.14 99.98
192 INT145520 Positive_regulation of Dss1 16 0.39 14.04 3.38 99.98
193 INT46384 Binding of TRGC1 16 0.41 4.87 1.28 99.98
194 INT50037 Localization of Il5 7 0.58 4.14 2.3 99.98
195 INT14103 Regulation of Hrh1 6 0.44 2.67 2.74 99.98
196 INT22815 Positive_regulation of RB1 20 0.49 14.58 1.26 99.98
197 INT20208 Gene_expression of Slc3a2 7 0.40 0.71 0.63 99.98
198 INT157634 Regulation of Nkr-p1c 2 0.37 1.65 1.7 99.98
199 INT683 Positive_regulation of AVP 173 0.70 74.55 46.41 99.96
200 INT19393 Gene_expression of Gfm1 31 0.51 18.9 3.2 99.96
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