D:Respiratory Distress

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Disease Term
Synonyms Disease Hyaline Membrane, Diseases Hyaline Membrane, Distressed Breathing, Hyaline Membrane Disease, Hyaline Membrane Diseases, RESPIRATORY DISTRESS SYNDROME
Documents 930
Hot Single Events 128
Hot Interactions 7

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Respiratory Distress. They are ordered first by their relevance to Respiratory Distress and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT184120 Il4 Positive_regulation of Stat6 3 0.09 2.39 0.67 94.04
2 INT332247 Egf Positive_regulation of Stat6 1 0.13 1.23 0.19 94.04
3 INT332253 Il13 Positive_regulation of Stat6 1 0.08 1.18 0.19 94.04
4 INT332245 Pdgfa Positive_regulation of Stat6 1 0.07 1.22 0.19 94.04
5 INT236071 Binding of pf and Pv 1 0.02 2.4 0 88.32
6 INT194537 Binding of PAEP and Uox 1 0.10 1.12 0.14 88.16
7 INT332244 Il13 Positive_regulation of Gtf3a 1 0.01 1.21 0.15 85.96
8 INT81716 ITGAL Regulation of ITGB2 2 0.30 1.24 0.78 79.64
9 INT170121 ITGAL Regulation of CD44 1 0.07 1.07 0 79.64
10 INT170119 PECAM1 Regulation of Positive_regulation of ITGAL 1 0.01 1.07 0 79.64
11 INT170124 ITGAM Regulation of ITGB2 1 0.04 1.07 0 79.64
12 INT170120 PECAM1 Regulation of ITGAM 1 0.00 1.07 0 79.64
13 INT170118 PECAM1 Regulation of CD44 1 0.01 1.07 0 79.64
14 INT170123 ITGAL Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0 79.64
15 INT170125 ITGAM Regulation of Positive_regulation of PECAM1 1 0.01 1.07 0 79.64
16 INT170126 PECAM1 Regulation of ITGB2 1 0.01 1.07 0 79.64
17 INT170116 ITGAM Regulation of CD44 1 0.07 1.07 0 79.64
18 INT170114 ITGAM Regulation of Positive_regulation of ITGAL 1 0.04 1.07 0 79.64
19 INT170115 PECAM1 Regulation of ITGAL 1 0.00 1.07 0 79.64
20 INT170127 Binding of ITGAL and PECAM1 2 0.01 2.71 0.75 72.72
21 INT170128 Binding of ITGAL and ITGB2 2 0.04 1.6 0.28 72.72
22 INT235956 Binding of Aqp4 and NMO-IgG 1 0.04 4.53 0.5 68.16
23 INT321601 Binding of C3 and PRTN3 1 0.00 0.99 0.27 65.64
24 INT321602 Binding of C4A and PRTN3 1 0.00 0.99 0.27 65.64
25 INT235968 NMO-IgG Positive_regulation of Nqo1 1 0.00 2.11 0.03 65.28
26 INT332250 Stat6 Positive_regulation of Gene_expression of Pdgfa 1 0.05 1.33 0.12 64.96
27 INT332252 Stat6 Positive_regulation of Gene_expression of Il13 1 0.08 1.32 0.12 64.96
28 INT262257 Positive_regulation of NOS2 Positive_regulation of AMIGO2 1 0.02 0.99 0.16 60.56
29 INT332251 Il13 Positive_regulation of Stat1 1 0.14 1.4 0.18 51.56
30 INT222022 Binding of Mmp8 and Mmp9 1 0.28 1.98 0.15 48.36
31 INT348220 Glp1r Regulation of Slc2a1 1 0.12 0.66 0.03 32.08
32 INT348225 Glp1r Regulation of Localization of Slc2a4 1 0.36 0.66 0.03 32.08
33 INT348226 Glp1r Regulation of Localization of Slc2a1 1 0.26 1.03 0.03 32.08
34 INT348223 Glp1r Regulation of Positive_regulation of Slc2a4 1 0.26 0.66 0.03 32.08
35 INT348224 Glp1r Regulation of Slc2a4 1 0.26 0.66 0.03 32.08
36 INT292334 Binding of Sds and Fig4 1 0.02 0.07 0.05 22.88
37 INT235969 Binding of Ighg1 and Nqo1 1 0.01 2.63 0.04 21.76
38 INT194538 Binding of PAEP and Negative_regulation of Uox 1 0.13 0.31 0 21.44
39 INT198653 TNF Positive_regulation of MIF 1 0.15 3.81 1.55 5.00
40 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2 5.00
41 INT83616 Binding of IL6 and IL8 5 0.09 5.8 1.11 5.00
42 INT178663 Binding of CXCR3 and TH1L 2 0.04 2.24 1.01 5.00
43 INT209151 OXT Positive_regulation of PNLIP 1 0.08 0.73 0.99 5.00
44 INT195668 Binding of F2 and THBD 7 0.08 5.67 0.98 5.00
45 INT333140 Abo2 Regulation of Positive_regulation of Ltp 1 0.00 0.64 0.91 5.00
46 INT333141 Binding of Ltp and Abo2 1 0.00 0.79 0.89 5.00
47 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
48 INT222024 Mapk8 Regulation of Mapk14 2 0.17 0.83 0.79 5.00
49 INT195778 Binding of APC and PROCR 7 0.19 3.78 0.73 5.00
50 INT179203 NLRP1 Regulation of Gene_expression of TNF 1 0.31 1.73 0.6 5.00
51 INT209152 Regulation of OXT Positive_regulation of PNLIP 1 0.05 0.42 0.54 5.00
52 INT127320 Gpx3 Regulation of Akt1 2 0.00 3.11 0.53 5.00
53 INT235975 Binding of AQP4 and IgG 2 0.04 4.11 0.53 5.00
54 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
55 INT178664 Binding of CCR5 and TH1L 1 0.04 1.04 0.44 5.00
56 INT347563 Abat Positive_regulation of Gopc 1 0.04 0.2 0.43 5.00
57 INT332248 Ccl2 Positive_regulation of Ctgf 1 0.04 1.13 0.42 5.00
58 INT198652 F2 Positive_regulation of Gene_expression of CD36 1 0.03 1.32 0.37 5.00
59 INT179201 NLRP1 Regulation of Gene_expression of IL10 1 0.06 0.77 0.36 5.00
60 INT179202 NLRP1 Regulation of Gene_expression of IL6 1 0.07 0.77 0.36 5.00
61 INT178662 IFN1@ Positive_regulation of CXCL9 1 0.20 0.5 0.36 5.00
62 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34 5.00
63 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
64 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
65 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
66 INT198642 GPI Positive_regulation of TNF 1 0.03 0.98 0.33 5.00
67 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
68 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
69 INT312803 F2 Positive_regulation of NPEPPS 1 0.01 1.32 0.32 5.00
70 INT235971 Positive_regulation of Binding of Nqo1 and NMO-IgG 1 0.00 1.86 0.32 5.00
71 INT312802 F2 Positive_regulation of Binding of NPEPPS 1 0.01 1.33 0.32 5.00
72 INT332255 Ptger2 Positive_regulation of Localization of Col7a1 1 0.00 0.92 0.31 5.00
73 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
74 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
75 INT347562 Abat Positive_regulation of Mki67 1 0.03 0 0.3 5.00
76 INT235958 Binding of Ighg1 and Aqp4 1 0.14 1.32 0.3 5.00
77 INT235977 Binding of AQP4 and Ighg1 1 0.03 1.31 0.3 5.00
78 INT235957 Binding of Mog and Bcr 1 0.02 1.13 0.29 5.00
79 INT235962 Binding of Bcr and Trav6-3 1 0.00 1.12 0.29 5.00
80 INT198640 TNF Positive_regulation of ISYNA1 1 0.04 1.07 0.29 5.00
81 INT235966 Binding of Mog and Trav6-3 1 0.01 1.07 0.29 5.00
82 INT332246 Ros1 Positive_regulation of Stat1 1 0.02 0.46 0.27 5.00
83 INT235959 Nqo1 Positive_regulation of Localization of Aqp4 1 0.02 1.39 0.26 5.00
84 INT198648 VCAM1 Positive_regulation of CADM1 1 0.00 1.1 0.25 5.00
85 INT332242 Binding of Egf and Pdgfa 1 0.07 0.97 0.25 5.00
86 INT179200 Binding of ICAM1 and IL8 1 0.03 1.02 0.25 5.00
87 INT235974 Negative_regulation of Binding of APC and Trav6-3 1 0.00 1.15 0.24 5.00
88 INT198644 TNF Positive_regulation of CADM1 1 0.02 1.07 0.24 5.00
89 INT198643 CD36 Positive_regulation of CADM1 1 0.01 1.07 0.24 5.00
90 INT235972 Negative_regulation of Binding of APC and Bcr 1 0.01 1.15 0.24 5.00
91 INT235973 Binding of APC and Bcr 1 0.01 1.14 0.24 5.00
92 INT235976 Binding of APC and Trav6-3 2 0.01 2.62 0.24 5.00
93 INT235967 Binding of Ighm and Nqo1 1 0.00 1.45 0.23 5.00
94 INT308084 Binding of HSPG2 and OXT 1 0.04 0.25 0.23 5.00
95 INT254687 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Mmp13 1 0.06 0.2 0.2 5.00
96 INT254683 Positive_regulation of Map2k1 Positive_regulation of Gene_expression of Plaur 1 0.01 0.07 0.18 5.00
97 INT222025 Gpx3 Regulation of EPHB2 1 0.01 1.41 0.18 5.00
98 INT254691 Gopc Positive_regulation of Positive_regulation of Map2k2 1 0.07 0.07 0.18 5.00
99 INT222023 Gpx3 Regulation of Mapk8 1 0.01 1.43 0.18 5.00
100 INT254698 Gopc Positive_regulation of Positive_regulation of Map2k1 1 0.06 0.07 0.18 5.00
101 INT326464 KNG1 Positive_regulation of SERPING1 1 0.19 1.53 0.18 5.00
102 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18 5.00
103 INT254685 Map2k2 Positive_regulation of Mmp3 1 0.04 0.08 0.18 5.00
104 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
105 INT180503 Binding of SARS and PSMD6 1 0.22 2.44 0.16 5.00
106 INT198638 GPI Positive_regulation of Gene_expression of TNF 1 0.03 1.44 0.15 5.00
107 INT318305 Binding of NOD2 and NLRP3 1 0.08 1.76 0.15 5.00
108 INT318306 Binding of DPEP1 and NLRP3 1 0.03 1.77 0.15 5.00
109 INT246365 CALM1 Regulation of MAP2K6 1 0.00 0.34 0.15 5.00
110 INT286476 Binding of App and Itm2b 1 0.47 5.24 0.14 5.00
111 INT331628 Binding of HLA-DQA2 and Pain1 1 0.01 2.13 0.14 5.00
112 INT332254 Pdgfa Positive_regulation of Stat3 1 0.02 0.52 0.14 5.00
113 INT331627 Binding of HLA-DRB3 and Pain1 1 0.00 2.15 0.14 5.00
114 INT332256 Pdgfa Positive_regulation of SOAT1 1 0.01 0.51 0.14 5.00
115 INT332243 Pdgfa Positive_regulation of Stat1 1 0.06 0.52 0.14 5.00
116 INT235961 Binding of Nqo1 and Aqp4 1 0.02 0.9 0.14 5.00
117 INT223084 Binding of Pdgfa and Pdgfb 2 0.17 0.83 0.13 5.00
118 INT246364 GOPC Regulation of SETBP1 1 0.02 0.98 0.13 5.00
119 INT335565 Binding of KDM5D and SPNS1 1 0.02 0 0.13 5.00
120 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13 5.00
121 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
122 INT254643 Binding of Mapk8ip1 and Slc9a3r2 1 0.00 0.27 0.12 5.00
123 INT331612 ETV4 Positive_regulation of Gene_expression of TGFB1 1 0.00 1.32 0.12 5.00
124 INT265919 Binding of PLEK and Adp 1 0.01 0.38 0.11 5.00
125 INT264839 Positive_regulation of Binding of Eno2 and Tpr 1 0.00 0.17 0.1 5.00
126 INT264838 Binding of Eno2 and Spp1 1 0.00 0.17 0.1 5.00
127 INT264836 Binding of Eno2 and Tpr 1 0.00 0.17 0.1 5.00
128 INT292328 Binding of Sds and Mb 1 0.11 0.24 0.1 5.00
129 INT262255 Binding of APC and F2R 1 0.05 3 0.1 5.00
130 INT282684 FECH Positive_regulation of Negative_regulation of Ssbp3 1 0.00 1.54 0.08 5.00
131 INT254641 CGA Positive_regulation of AGT 1 0.17 1.51 0.08 5.00
132 INT254640 CGA Positive_regulation of REN 1 0.07 1.51 0.08 5.00
133 INT235964 Binding of Atp9a and Aqp4 1 0.01 0.55 0.08 5.00
134 INT254639 CGA Positive_regulation of Gene_expression of AGT 1 0.18 1.51 0.08 5.00
135 INT331626 Edn1 Positive_regulation of Itk 1 0.00 0.57 0.07 5.00
136 INT331629 Binding of TGFB1 and Positive_regulation of Gene_expression of Itk 1 0.00 0.84 0.07 5.00
137 INT246363 SETBP1 Regulation of GBP2 1 0.02 0.4 0.06 5.00
138 INT264835 Binding of Creb1 and Tpr 1 0.01 0.05 0.06 5.00
139 INT235963 Snta1 Regulation of Gene_expression of Aqp4 1 0.41 0.23 0.05 5.00
140 INT307157 Berr1 Regulation of Mgst1 1 0.00 1.51 0.05 5.00
141 INT198639 S100A12 Positive_regulation of TNF 1 0.15 1.49 0.04 5.00
142 INT198646 S100A12 Positive_regulation of IL1B 1 0.01 1.49 0.04 5.00
143 INT296893 Nps Negative_regulation of Gene_expression of REN 1 0.00 1.05 0.04 5.00
144 INT262256 Binding of PROC and AMIGO2 1 0.00 0.72 0.04 5.00
145 INT198651 Positive_regulation of S100A12 Positive_regulation of TNF 1 0.15 1.5 0.04 5.00
146 INT198650 Positive_regulation of S100A12 Positive_regulation of IL1B 1 0.01 1.5 0.04 5.00
147 INT348222 Binding of Ins1 and Glp1r 1 0.05 0.82 0.03 5.00
148 INT200063 Binding of MAGED1 and Ngfr 1 0.44 0.45 0 5.00
149 INT354097 Timp1 Negative_regulation of Localization of NFKB2 1 0.04 0.94 0 5.00
150 INT268723 Binding of PRB1 and ROS1 1 0.01 0 0 5.00
151 INT200060 Binding of Nuc and Ndn 1 0.10 0.29 0 5.00
152 INT200058 Binding of Ndn and Bbs4 1 0.30 0.29 0 5.00
153 INT254689 Gene_expression of Map2k2 Positive_regulation of Map2k1 1 0.30 0.4 0 5.00
154 INT320959 Binding of HRAS and HMHA1 1 0.00 0.37 0 5.00
155 INT254707 Positive_regulation of Map2k1 Regulation of Gene_expression of BAK1 1 0.05 0.67 0 5.00
156 INT254692 Positive_regulation of Map2k1 Regulation of Gene_expression of Mdk 1 0.05 0.42 0 5.00
157 INT353910 Binding of CRP and UROD 1 0.06 0.34 0 5.00
158 INT307155 Char1 Regulation of Ppig 1 0.00 0.92 0 5.00
159 INT254695 Positive_regulation of Map2k2 Regulation of Mcl1 1 0.03 0.84 0 5.00
160 INT292330 Binding of Mb and Fig4 1 0.06 0 0 5.00
161 INT200062 Binding of Ngfr and Bbs4 1 0.30 0.3 0 5.00
162 INT331611 NKX2-1 Regulation of Transcription of SFTPB 1 0.01 0.49 0 5.00
163 INT292326 Binding of Fig4 and LOC360919 1 0.00 0.08 0 5.00
164 INT200053 Binding of Nuc and Ngfr 1 0.10 0.3 0 5.00
165 INT200057 Binding of Ndn and Ngfr 1 0.43 1.96 0 5.00
166 INT307160 Regulation of Binding of Cyp2a5 and Ppig 1 0.05 1.22 0 5.00
167 INT213824 Binding of PDB1 and ANTXR2 1 0.16 0 0 5.00
168 INT292329 Binding of Sds and LOC360919 1 0.01 0.08 0 5.00
169 INT307159 Cyp2a5 Regulation of Ppig 1 0.03 0.91 0 5.00
170 INT322931 Binding of MOCS1 and Litaf 1 0.00 0.82 0 5.00
171 INT254693 Gene_expression of Map2k1 Regulation of Map2k2 1 0.29 0.78 0 5.00
172 INT200064 Binding of MAGED1 and Mageh1 1 0.30 0.23 0 5.00
173 INT254686 Gene_expression of Map2k1 Regulation of Gene_expression of Mdk 1 0.08 0.42 0 5.00
174 INT304776 Binding of KMS and KTWS 1 0.01 2.24 0 5.00
175 INT254703 Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 0.91 0 5.00
176 INT254696 Map2k2 Regulation of Map2k1 1 0.18 0.78 0 5.00
177 INT200061 Binding of Ngfr and Fez1 1 0.31 0.3 0 5.00
178 INT292327 Binding of Mb and LOC360919 1 0.01 0.08 0 5.00
179 INT254708 Map2k2 Positive_regulation of Phosphorylation of MAPK1 1 0.11 0.86 0 5.00
180 INT194516 UOX Positive_regulation of Gene_expression of PAEP 1 0.12 0.21 0 5.00
181 INT254699 Positive_regulation of Map2k2 Regulation of Bcl2l1 1 0.04 0.89 0 5.00
182 INT235960 Binding of Aqp4 and H47 1 0.01 0.13 0 5.00
183 INT254706 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0 5.00
184 INT200056 Binding of Ndn and Fez1 1 0.31 0.28 0 5.00
185 INT200065 Binding of MAGED1 and Ntf3 1 0.32 0.23 0 5.00
186 INT254688 Gene_expression of Map2k2 Regulation of Gene_expression of Mdk 1 0.09 0.42 0 5.00
187 INT254704 Positive_regulation of Map2k1 Positive_regulation of Phosphorylation of MAPK1 1 0.10 1.43 0 5.00
188 INT354096 Timp1 Negative_regulation of Positive_regulation of NFKB2 1 0.04 0.94 0 5.00
189 INT186449 Binding of SFTPB and SFTPC 1 0.38 0.09 0 5.00
190 INT307158 Binding of Cyp2a5 and Ppig 1 0.04 1.22 0 5.00
191 INT254702 Map2k1 Positive_regulation of Phosphorylation of MAPK3 1 0.07 0.91 0 5.00
192 INT200059 Gtf3a Positive_regulation of Ndn 1 0.06 0.89 0 5.00
193 INT254684 Map2k2 Positive_regulation of Map2k1 1 0.45 0.4 0 5.00
194 INT200054 Binding of Ntf3 and Mageh1 1 0.24 0.22 0 5.00
195 INT320958 Binding of KRT31 and GOPC 1 0.01 0.52 0 5.00
196 INT254705 Map2k2 Positive_regulation of Phosphorylation of MAPK3 1 0.08 0.86 0 5.00
197 INT194539 UOX Positive_regulation of Gene_expression of Uox 1 0.39 0.21 0 5.00
198 INT200055 Binding of Ngfr and Mageh1 1 0.33 0.45 0 5.00
199 INT254694 Positive_regulation of Map2k2 Regulation of Bcl2 1 0.02 0.89 0 5.00
200 INT307156 Esr1 Positive_regulation of Hspa5 1 0.04 0.79 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Respiratory Distress. They are ordered first by their pain relevance and then by number of times they were reported in Respiratory Distress. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT201130 Localization of AES 31 0.63 25.45 5.12 100.00
2 INT355163 Regulation of Localization of AES 1 0.28 1.13 0 100.00
3 INT355161 Regulation of Localization of RASSF1 1 0.44 1.13 0 100.00
4 INT355162 Regulation of Localization of CDKN2A 1 0.40 1.13 0 100.00
5 INT236073 Positive_regulation of DARC 1 0.02 1.38 0 100.00
6 INT236072 Binding of DARC 8 0.03 6.01 0.03 99.98
7 INT186450 Negative_regulation of SFTPB 17 0.58 10.94 0.31 99.84
8 INT94007 Binding of Pphn 4 0.31 0.63 0.31 99.76
9 INT34599 Binding of TST 7 0.32 3.88 0.71 99.68
10 INT58477 Gene_expression of Chdh 33 0.74 39.48 19.78 99.62
11 INT186452 Positive_regulation of SFTPB 7 0.47 6.43 0.03 99.50
12 INT186459 Positive_regulation of SFTPC 4 0.45 4.64 0.36 99.50
13 INT186464 Positive_regulation of Binding of TAB1 1 0.04 0.85 0 99.50
14 INT147264 Gene_expression of CSR 2 0.29 0.6 0 99.30
15 INT186458 Negative_regulation of SFTPC 11 0.57 8.6 1.29 99.12
16 INT184624 Localization of CDKN2A 8 0.74 7.87 0.25 98.96
17 INT59954 Localization of RASSF1 3 0.73 3.12 0.07 98.96
18 INT227436 Negative_regulation of CSR 2 0.18 0.87 0 98.92
19 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 98.76
20 INT186457 Binding of TAB1 3 0.47 1.53 0.18 98.24
21 INT191289 Positive_regulation of Psrs1 1 0.01 0.43 0 98.12
22 INT36751 Gene_expression of ZMYND10 7 0.75 3.92 0.32 98.04
23 INT220861 Positive_regulation of Mmp8 14 0.50 12.21 4.6 98.00
24 INT143337 Binding of Aqp4 30 0.40 23.73 4.24 97.76
25 INT129016 Transcription of Ndn 2 0.65 1.42 0.07 97.76
26 INT111412 Positive_regulation of Sftpb 2 0.67 1.02 0.04 97.04
27 INT8547 Gene_expression of MUC16 116 0.78 75.97 12.18 96.72
28 INT11033 Positive_regulation of Gene_expression of MUC16 21 0.69 15.75 1.89 96.72
29 INT94881 Negative_regulation of Gene_expression of MUC16 4 0.42 2.51 0.61 96.72
30 INT227437 Positive_regulation of CSR 1 0.30 1.81 0 96.16
31 INT45167 Positive_regulation of ASAP1 32 0.60 17.09 1.84 95.76
32 INT76713 Regulation of Gene_expression of PECAM1 16 0.40 14.52 2.51 95.76
33 INT15699 Binding of Litaf 2 0.01 1.06 0.19 95.64
34 INT206658 Negative_regulation of NAPEPLD 2 0.04 2.18 0.1 95.36
35 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 95.24
36 INT8545 Negative_regulation of MUC16 19 0.57 15.96 2.81 95.24
37 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 95.20
38 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 94.96
39 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 94.96
40 INT17641 Gene_expression of NLRP1 33 0.73 8.85 6.02 94.92
41 INT194533 Binding of UOX 2 0.47 3.86 0.2 94.24
42 INT1708 Gene_expression of OXTR 56 0.78 6.92 10.69 94.04
43 INT62331 Gene_expression of TNFRSF8 26 0.72 17.75 2.08 93.88
44 INT224396 Negative_regulation of UROD 2 0.30 1.57 0.12 93.84
45 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 93.60
46 INT4936 Localization of Tacr1 125 0.80 35.7 107.7 93.60
47 INT267892 Gene_expression of Prkag2 3 0.62 3.59 0 93.60
48 INT330511 Gene_expression of Bmpr1a 1 0.54 1.9 0 93.60
49 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 93.36
50 INT92388 Gene_expression of ALK 16 0.78 22.46 2.26 93.28
51 INT205005 Transcription of SPECC1 3 0.59 1.28 0.14 93.08
52 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 93.00
53 INT137347 Regulation of Gene_expression of Chdh 3 0.44 3.01 0.62 92.96
54 INT29477 Transcription of Oprl1 52 0.72 5.05 30.52 92.44
55 INT1614 Gene_expression of Oprl1 164 0.78 31.43 127.74 92.44
56 INT40800 Regulation of Gene_expression of Oprl1 8 0.61 1.82 4.73 92.44
57 INT114848 Regulation of Transcription of Oprl1 3 0.62 1.79 2.44 92.44
58 INT24536 Regulation of Localization of Tacr1 5 0.30 3.39 6.44 92.24
59 INT80486 Gene_expression of FECH 13 0.54 10.42 4.8 91.76
60 INT64792 Positive_regulation of Gene_expression of ITGAM 39 0.69 23.21 6.71 91.52
61 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 91.52
62 INT70326 Positive_regulation of Gene_expression of ITGB2 24 0.67 15.42 3.86 91.52
63 INT186461 Gene_expression of SFTPB 10 0.73 8.69 1.09 91.20
64 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 91.12
65 INT10918 Gene_expression of ITGB2 93 0.76 71.8 16.34 91.12
66 INT36449 Negative_regulation of G6PD 74 0.59 54.15 8.85 90.80
67 INT42242 Binding of MERTK 1 0.36 0.77 0.18 90.32
68 INT205651 Localization of FUS 4 0.36 4.15 0.31 90.24
69 INT286475 Positive_regulation of ITM2B 1 0.03 1.83 0.1 90.12
70 INT186454 Binding of SFTPB 3 0.35 1.48 0.24 90.04
71 INT159450 Localization of SP3P 1 0.00 0.89 0.5 89.80
72 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 89.52
73 INT200039 Negative_regulation of Ndn 1 0.41 5.89 0.29 88.84
74 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 88.56
75 INT106307 Positive_regulation of UROD 27 0.49 16.63 2.19 88.40
76 INT173445 Positive_regulation of TAB1 3 0.49 0.9 0 88.16
77 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 88.16
78 INT186456 Gene_expression of SFTPC 2 0.75 11.46 2.38 88.08
79 INT186463 Negative_regulation of Gene_expression of SFTPC 2 0.42 4.52 0.75 88.08
80 INT50602 Transcription of Alb 3 0.52 1.71 0.39 87.88
81 INT987 Localization of TRH 37 0.78 10.53 11.1 87.48
82 INT23764 Regulation of Localization of TRH 4 0.45 0.75 1.4 87.48
83 INT10375 Negative_regulation of Gene_expression of RARA 1 0.57 0.97 0.22 87.36
84 INT160440 Positive_regulation of Crem 48 0.69 20.38 7.66 86.84
85 INT10374 Gene_expression of RARA 39 0.75 22.59 4.28 86.72
86 INT10373 Gene_expression of ADI1 8 0.25 5.97 0.92 86.72
87 INT62945 Negative_regulation of Gene_expression of SELL 12 0.58 12.86 3.23 86.40
88 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71 86.40
89 INT251815 Negative_regulation of SPECC1 1 0.37 1.95 0.04 86.28
90 INT67822 Binding of SERPINH1 17 0.36 19.05 7.24 86.04
91 INT480 Negative_regulation of Localization of Avp 151 0.59 27.64 63.72 85.92
92 INT236068 Binding of Pv 1 0.22 2.25 0 85.60
93 INT187422 Negative_regulation of MTTP 23 0.57 11.75 0.24 85.12
94 INT106745 Localization of CRP 65 0.81 66.44 15.21 84.88
95 INT165963 Gene_expression of Map2k2 37 0.75 20.68 0.66 84.88
96 INT224398 Localization of UROD 3 0.49 1.71 0.25 84.88
97 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 84.68
98 INT477 Localization of Avp 813 0.81 131.58 300.4 84.64
99 INT13085 Positive_regulation of ACE 50 0.70 44.2 8.31 84.52
100 INT191542 Binding of ABCA3 1 0.22 1.61 0.03 84.12
101 INT138287 Gene_expression of Map2k1 69 0.65 46.14 1.02 84.08
102 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 84.00
103 INT134470 Positive_regulation of Map2k1 74 0.49 46.07 3.02 83.56
104 INT254666 Positive_regulation of Map2k2 37 0.56 23.85 1.35 83.56
105 INT254673 Positive_regulation of Positive_regulation of Map2k1 3 0.35 1.65 0.11 83.56
106 INT254677 Positive_regulation of Positive_regulation of Map2k2 1 0.40 0.94 0 83.56
107 INT115046 Gene_expression of Crem 68 0.77 27.24 10.01 83.32
108 INT93546 Regulation of UROD 4 0.32 2.9 0.37 83.20
109 INT229741 Phosphorylation of AOC2 1 0.09 0.57 0.07 82.60
110 INT17564 Gene_expression of Gpt 322 0.75 208.51 60.36 82.36
111 INT62166 Positive_regulation of Gene_expression of Gpt 64 0.50 39.13 9.69 82.36
112 INT102020 Gene_expression of Creb1 190 0.78 57.31 59.77 82.32
113 INT186460 Transcription of ASAP1 5 0.56 3.02 0.03 81.52
114 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 80.88
115 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 80.88
116 INT30731 Positive_regulation of Gene_expression of GGT1 8 0.49 6.55 1.15 80.88
117 INT1533 Negative_regulation of AGT 105 0.42 46.54 16.92 80.80
118 INT119838 Positive_regulation of PTEN 25 0.67 21.71 2.5 80.64
119 INT7041 Negative_regulation of SP3P 3 0.00 1.45 2.59 80.48
120 INT48262 Positive_regulation of SP3P 3 0.00 1.55 2.06 80.48
121 INT159449 Negative_regulation of Positive_regulation of SP3P 1 0.00 0.42 0.25 80.48
122 INT90307 Positive_regulation of ZNF85 1 0.07 0.39 0.08 80.44
123 INT10248 Gene_expression of KRT20 436 0.78 231.96 32.88 80.40
124 INT180535 Gene_expression of BPI 4 0.52 3.61 0.91 80.40
125 INT274193 Negative_regulation of PES1 7 0.57 3.25 0.77 80.24
126 INT233856 Regulation of SFTPC 4 0.60 2.25 0.19 80.24
127 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 80.08
128 INT3811 Negative_regulation of PAEP 36 0.50 23.7 5.18 80.04
129 INT194521 Negative_regulation of Uox 7 0.52 4.93 0.41 79.88
130 INT20991 Regulation of ITGAM 9 0.45 5.46 2.27 79.64
131 INT20992 Regulation of ITGB2 11 0.37 9.04 1.73 79.64
132 INT12942 Regulation of ITGAL 8 0.35 3.29 1.57 79.64
133 INT63356 Regulation of CD44 6 0.23 6.29 0.61 79.64
134 INT186451 Positive_regulation of Negative_regulation of SFTPB 1 0.47 0.52 0 79.44
135 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 79.40
136 INT194530 Gene_expression of UOX 17 0.65 11.78 0.17 79.36
137 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 78.56
138 INT10917 Positive_regulation of ITGAM 31 0.67 16.39 6.69 78.56
139 INT10919 Positive_regulation of ITGB2 25 0.67 13.75 5.45 78.56
140 INT61418 Positive_regulation of ITGAL 24 0.14 12.86 2.3 78.56
141 INT91430 Positive_regulation of CD44 25 0.69 15.43 1.76 78.56
142 INT220335 Gene_expression of UROD 34 0.54 24.53 2.89 78.24
143 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 78.16
144 INT4098 Negative_regulation of Antxr1 2 0.17 0.61 0.52 78.00
145 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 77.92
146 INT1536 Negative_regulation of NA 244 0.55 52.67 59.79 77.88
147 INT1756 Negative_regulation of DNAH8 105 0.59 42.73 20.24 77.60
148 INT173090 Regulation of INCENP 24 0.09 9.45 2.16 77.16
149 INT11390 Gene_expression of PF4 5 0.65 3.09 2.07 76.96
150 INT82646 Gene_expression of malformation 1 0.35 1.06 0.07 76.88
151 INT18644 Binding of OXT 6 0.31 1.22 0.55 76.84
152 INT11340 Positive_regulation of SLC17A5 120 0.67 113.52 14.5 76.28
153 INT157892 Binding of PNLIP 5 0.25 4.58 0.65 76.16
154 INT236074 Gene_expression of DARC 9 0.28 11.4 0 76.00
155 INT180523 Positive_regulation of CEACAM8 4 0.49 2.94 0.36 75.96
156 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 75.92
157 INT90306 Gene_expression of ZNF85 1 0.11 0.37 0.08 75.80
158 INT2837 Regulation of PAEP 17 0.53 7.84 3.17 75.76
159 INT65286 Binding of ARIH1 10 0.48 4.3 0.76 75.56
160 INT146758 Gene_expression of LCN2 45 0.78 38.29 2.97 74.72
161 INT121788 Localization of BCS1L 11 0.73 10.16 1.14 74.52
162 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 74.48
163 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 74.48
164 INT180532 Localization of BPI 2 0.58 1.15 0.12 73.80
165 INT227434 Binding of CSR 1 0.21 1.22 0 73.72
166 INT621 Positive_regulation of SERPINH1 19 0.57 21.52 8.44 73.68
167 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 73.60
168 INT63348 Regulation of PECAM1 14 0.40 16.05 0.97 73.36
169 INT71787 Positive_regulation of MAPK3 37 0.67 17.5 17.88 73.32
170 INT232567 Binding of Spl 2 0.31 1.88 0.1 73.32
171 INT274238 Positive_regulation of AIP 2 0.42 8.14 0.97 73.00
172 INT27242 Gene_expression of PGR 153 0.75 98.77 12.79 72.68
173 INT11699 Binding of HLA-E 85 0.47 52.51 13.41 72.60
174 INT42032 Localization of PNLIP 4 0.14 3.44 0.41 72.56
175 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 71.08
176 INT11650 Negative_regulation of Gpt 122 0.59 69.15 30.36 71.00
177 INT2614 Gene_expression of CGA 187 0.78 105.89 24.77 70.92
178 INT80657 Gene_expression of SLC17A5 50 0.75 39.98 5.44 70.48
179 INT178193 Negative_regulation of Stat3 25 0.58 17.82 2.27 70.32
180 INT30777 Negative_regulation of SELL 20 0.56 18.05 7.32 70.16
181 INT46121 Negative_regulation of SERPINH1 14 0.38 10.84 4.41 70.08
182 INT92343 Negative_regulation of CENPJ 20 0.57 6.25 0.2 69.88
183 INT90305 Negative_regulation of ZNF85 1 0.06 0.35 0.07 69.84
184 INT201474 Regulation of Acta1 3 0.18 1.98 0 69.56
185 INT41892 Gene_expression of HBM 48 0.64 28.32 5.64 69.36
186 INT2732 Gene_expression of VIP 74 0.78 24.57 33.72 68.56
187 INT660 Negative_regulation of REN 194 0.59 82.06 29.46 68.52
188 INT71634 Gene_expression of SLC6A3 45 0.78 13.48 15.23 68.52
189 INT99586 Binding of IRF6 60 0.36 27.87 13.2 68.36
190 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 68.16
191 INT20205 Binding of IgG 108 0.46 66.68 8.57 68.16
192 INT180534 Gene_expression of SARS 40 0.59 35.47 0.81 68.00
193 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 67.64
194 INT165379 Gene_expression of CEACAM8 8 0.75 4.21 1.64 66.28
195 INT114874 Gene_expression of Stat3 78 0.76 53.99 9.49 66.16
196 INT16996 Gene_expression of PRTN3 113 0.75 85.61 22.57 65.64
197 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 64.76
198 INT46221 Positive_regulation of Gene_expression of IgG 46 0.53 33.66 7.7 64.76
199 INT21246 Negative_regulation of ATP1A4 3 0.10 3.3 0.79 64.48
200 INT100939 Gene_expression of Il13 176 0.73 125.1 43.38 64.12
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