D:Retinal Vein Occlusion

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Disease Term
Synonyms Occlusion Retinal Vein, Occlusions Retinal Vein, Retinal Vein Occlusions, Retinal Vein Thromboses, Retinal Vein Thrombosis, Thromboses Retinal Vein, Thrombosis Retinal Vein, Vein Occlusion Retinal, Vein Occlusions Retinal, Vein Thromboses Retinal, Vein Thrombosis Retinal
Documents 58
Hot Single Events 34
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Retinal Vein Occlusion. They are ordered first by their relevance to Retinal Vein Occlusion and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT288026 PROC Positive_regulation of Gene_expression of VEGFA 1 0.01 0.5 0.15 66.12
2 INT263587 Pdia3 Negative_regulation of Binding of Esr1 1 0.07 1.86 0.26 63.24
3 INT288025 VEGFA Regulation of IL6 1 0.36 0.26 0.03 18.56
4 INT288028 VEGFA Regulation of IL8 1 0.36 0.26 0.03 18.32
5 INT288027 VEGFA Regulation of CCL2 1 0.44 0.26 0.03 17.96
6 INT283126 Dag1 Positive_regulation of Localization of Aqp4 1 0.47 0.2 0.07 5.00
7 INT283125 Gtf3a Positive_regulation of Gfap 1 0.02 0.43 0 5.00
8 INT228002 Binding of Loxl1 and Fbln5 1 0.34 1.57 0 5.00
9 INT263585 Binding of Phlda2 and Gmcl1 1 0.02 0.59 0 5.00
10 INT228005 Binding of Eln and Loxl1 1 0.35 1.58 0 5.00
11 INT283122 Binding of Dag1 and Sptbn1 1 0.00 0.07 0 5.00
12 INT263584 Hspa5 Positive_regulation of Myo1b 1 0.00 1.02 0 5.00
13 INT228006 Positive_regulation of Binding of Eln and Loxl1 1 0.37 0.55 0 5.00
14 INT263586 Hspa5 Positive_regulation of Esr1 1 0.15 1.01 0 5.00
15 INT228004 Positive_regulation of Binding of Loxl1 and Fbln5 1 0.35 0.54 0 5.00
16 INT266098 Bdnf Negative_regulation of Negative_regulation of 1190002H23Rik 1 0.05 0.41 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Retinal Vein Occlusion. They are ordered first by their pain relevance and then by number of times they were reported in Retinal Vein Occlusion. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT5913 Binding of OPA1 12 0.41 9.33 2.92 99.98
2 INT34976 Positive_regulation of Gene_expression of OPA1 4 0.43 4.21 0.4 99.92
3 INT15367 Gene_expression of OPA1 35 0.67 24.9 5.45 99.68
4 INT5180 Binding of Serpinc1 27 0.36 13.39 2.47 99.66
5 INT9657 Positive_regulation of Gene_expression of Il6 237 0.70 180.45 63.6 99.58
6 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.58
7 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.34
8 INT9659 Gene_expression of Il6 991 0.78 715.11 265.57 99.34
9 INT591 Negative_regulation of Serpinc1 44 0.57 31.73 8.82 99.28
10 INT33854 Localization of OPA1 19 0.65 10.55 5.04 98.54
11 INT159060 Localization of PDR 8 0.65 10.45 0.96 98.48
12 INT288032 Negative_regulation of Localization of PDR 1 0.20 1.24 0.19 98.48
13 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 98.16
14 INT86111 Positive_regulation of Positive_regulation of VEGFA 38 0.69 33.81 5.78 98.16
15 INT80124 Negative_regulation of VEGFA 450 0.58 311.19 44.53 98.12
16 INT174868 Regulation of Negative_regulation of VEGFA 4 0.43 4.51 0.63 97.24
17 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 95.32
18 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 95.20
19 INT99690 Negative_regulation of Positive_regulation of VEGFA 30 0.58 14.56 4.79 93.00
20 INT92248 Negative_regulation of F5 7 0.43 3.28 0.4 92.72
21 INT67980 Positive_regulation of Positive_regulation of CCL2 7 0.49 5.89 1.85 92.72
22 INT75832 Positive_regulation of Positive_regulation of IL8 30 0.70 20.77 6.05 92.72
23 INT11047 Positive_regulation of Positive_regulation of IL6 45 0.66 28.7 9.37 92.72
24 INT67981 Positive_regulation of CCL2 165 0.70 136.84 61.85 90.36
25 INT10838 Positive_regulation of IL8 381 0.70 295.51 101.62 90.36
26 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 90.36
27 INT9647 Gene_expression of PROC 163 0.65 89.76 26.75 89.92
28 INT3537 Positive_regulation of Car2 413 0.56 103.51 94.35 87.52
29 INT170504 Positive_regulation of Gene_expression of Car2 60 0.41 19.1 8.45 87.52
30 INT164112 Localization of 1190002H23Rik 4 0.65 1.34 0.67 87.08
31 INT30170 Gene_expression of Car2 330 0.66 77.26 46.76 86.36
32 INT93350 Binding of Lepr 17 0.05 27.21 1.5 85.12
33 INT1767 Positive_regulation of PROC 83 0.67 54.14 17 83.48
34 INT80939 Positive_regulation of PDR 8 0.55 5.43 0.67 81.72
35 INT48692 Binding of VEGFA 345 0.48 210.3 21.31 77.28
36 INT9210 Regulation of IL6 166 0.62 125.61 49.95 76.16
37 INT10835 Regulation of IL8 79 0.49 53.04 24.14 76.16
38 INT66857 Regulation of CCL2 39 0.53 28.55 18.35 76.16
39 INT4535 Localization of PROC 106 0.73 76.24 21.1 75.16
40 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 74.24
41 INT184696 Positive_regulation of Xbp1 12 0.60 13.6 1.06 74.08
42 INT116150 Positive_regulation of Ddit3 26 0.67 22.58 5.01 74.08
43 INT165800 Positive_regulation of Ddit3 17 0.67 11.69 1.21 74.08
44 INT116144 Positive_regulation of Positive_regulation of Ddit3 2 0.41 2.95 1.2 74.08
45 INT173223 Negative_regulation of BRCA2 7 0.54 6.79 0.25 73.60
46 INT119062 Negative_regulation of BRCA1 12 0.49 13.7 1.36 73.24
47 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 72.00
48 INT202817 Gene_expression of Dag1 16 0.75 7.82 1.3 71.28
49 INT283119 Regulation of Dag1 4 0.44 1.98 0.65 64.32
50 INT322936 Positive_regulation of GSS 1 0.15 0.37 0 60.80
51 INT211095 Negative_regulation of Dag1 14 0.57 7.18 1.07 59.36
52 INT283102 Positive_regulation of Dag1 1 0.49 1.31 0.21 59.36
53 INT37296 Binding of Esr1 117 0.43 62.51 27.33 58.76
54 INT180588 Gene_expression of HEYL 13 0.52 8.37 1.19 56.52
55 INT272274 Localization of NARFL 24 0.60 27.55 1.18 53.68
56 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 51.12
57 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 50.96
58 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 50.88
59 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 50.52
60 INT109650 Gene_expression of Aqp4 87 0.78 51.52 20.72 40.16
61 INT283112 Gene_expression of Kcnj14 1 0.03 2.48 0.53 39.28
62 INT12339 Localization of IL8 437 0.81 251.87 117.39 38.52
63 INT12082 Localization of IL6 365 0.81 241.78 105.78 38.52
64 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 38.52
65 INT65698 Localization of CCL2 118 0.81 77.54 32.69 38.52
66 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 37.04
67 INT266875 Positive_regulation of Narfl 37 0.05 38.43 3.73 35.52
68 INT283120 Regulation of Gene_expression of Dag1 4 0.52 1.32 0.38 31.92
69 INT95696 Gene_expression of Dmd 130 0.68 26.02 5.34 31.44
70 INT216105 Regulation of Gene_expression of Dmd 7 0.36 2.55 0.41 31.44
71 INT283101 Negative_regulation of Gene_expression of Dag1 1 0.57 0.96 0 31.12
72 INT283108 Regulation of Localization of Aqp4 1 0.41 0.44 0.23 28.96
73 INT283109 Positive_regulation of Localization of Kcnj14 1 0.02 0.11 0.14 28.96
74 INT104563 Localization of Aqp4 10 0.73 7.82 2.54 27.84
75 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 27.68
76 INT283115 Localization of Kcnj14 5 0.04 1.47 0.31 26.96
77 INT180580 Binding of HEYL 7 0.17 4.49 1.15 20.48
78 INT242921 Positive_regulation of Aoc2-ps1 1 0.12 1.82 0.04 11.56
79 INT99688 Negative_regulation of Gene_expression of VEGFA 274 0.58 201.8 31.1 7.76
80 INT164115 Gene_expression of 1190002H23Rik 11 0.58 5.18 1.17 6.92
81 INT22383 Binding of IL2 59 0.48 39.06 8.56 6.44
82 INT2391 Negative_regulation of PTGS1 501 0.59 207.62 205.6 5.00
83 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
84 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
85 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
86 INT92669 Gene_expression of Bdnf 309 0.78 178.26 116.68 5.00
87 INT47243 Gene_expression of Prkcg 195 0.78 58.05 108.44 5.00
88 INT940 Negative_regulation of Ptgs1 219 0.59 104.34 95.97 5.00
89 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
90 INT56291 Gene_expression of Ros1 503 0.63 274.12 81.5 5.00
91 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 5.00
92 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 5.00
93 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
94 INT53083 Gene_expression of Ptgs2 153 0.78 90.04 50.39 5.00
95 INT170054 Negative_regulation of Gopc 280 0.38 117.89 42.4 5.00
96 INT173693 Localization of Gopc 249 0.65 70.49 38.81 5.00
97 INT106554 Positive_regulation of Gene_expression of Bdnf 73 0.70 42.58 30.77 5.00
98 INT5117 Negative_regulation of Gene_expression of IL2 118 0.59 52.33 29.96 5.00
99 INT169180 Binding of SNRNP70 204 0.47 119.1 29.3 5.00
100 INT102206 Regulation of Bdnf 37 0.62 28.54 28.78 5.00
101 INT66200 Gene_expression of Gfap 215 0.78 88.04 28.25 5.00
102 INT133876 Positive_regulation of Gene_expression of Ros1 141 0.32 75.55 27.45 5.00
103 INT145426 Positive_regulation of Ros1 185 0.56 106.76 27.21 5.00
104 INT9886 Gene_expression of Ptgs1 92 0.77 40.66 25.31 5.00
105 INT172458 Regulation of Gopc 155 0.53 62.57 24.86 5.00
106 INT113925 Localization of Bdnf 59 0.79 24.03 22.76 5.00
107 INT78901 Localization of CCL5 67 0.78 40.79 20.59 5.00
108 INT1060 Negative_regulation of Pla2g1b 50 0.57 22.91 18.12 5.00
109 INT102903 Regulation of Gene_expression of Bdnf 35 0.62 20.1 17.42 5.00
110 INT17237 Regulation of Esr1 74 0.43 49.09 17.25 5.00
111 INT170051 Positive_regulation of Gene_expression of Gopc 150 0.43 56.75 16.93 5.00
112 INT163479 Binding of Bdnf 36 0.48 25.77 14.83 5.00
113 INT1982 Regulation of NARFL 119 0.49 116.2 14.35 5.00
114 INT85510 Positive_regulation of Bdkrb2 23 0.70 12.08 12.68 5.00
115 INT27268 Localization of Gtf3a 71 0.21 56.93 12.51 5.00
116 INT122812 Gene_expression of SNRNP70 130 0.75 67 12.5 5.00
117 INT100821 Localization of Ros1 59 0.60 45.26 11.92 5.00
118 INT57187 Positive_regulation of Gfap 49 0.69 27.59 11.46 5.00
119 INT53082 Positive_regulation of Gene_expression of Ptgs2 47 0.64 25.39 11.39 5.00
120 INT109651 Negative_regulation of Aqp4 23 0.53 8.5 10.7 5.00
121 INT121796 Gene_expression of NeuN 92 0.78 23.18 10.53 5.00
122 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4 5.00
123 INT101474 Positive_regulation of Gene_expression of Gfap 61 0.70 38.3 10.35 5.00
124 INT2036 Localization of EGF 42 0.77 21.5 9.74 5.00
125 INT178306 Negative_regulation of Gene_expression of Gopc 71 0.37 26.43 9.74 5.00
126 INT56292 Negative_regulation of Gene_expression of Ros1 70 0.38 36.14 9.17 5.00
127 INT52442 Binding of Ptgs1 16 0.35 9.05 8.78 5.00
128 INT12975 Regulation of PLEK 21 0.60 13.62 8.28 5.00
129 INT76892 Gene_expression of FGFR1 45 0.69 23.6 7.56 5.00
130 INT21613 Gene_expression of Pla2g1b 25 0.68 9.05 6.39 5.00
131 INT22901 Negative_regulation of Gene_expression of Esr1 30 0.42 20.92 6.29 5.00
132 INT8106 Gene_expression of GGT1 31 0.75 18.65 6.1 5.00
133 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 5.00
134 INT155348 Positive_regulation of Aqp4 14 0.63 9.92 5.53 5.00
135 INT43997 Positive_regulation of Gene_expression of Esr1 57 0.51 36.66 5.51 5.00
136 INT128302 Localization of NeuN 24 0.73 9.81 5.27 5.00
137 INT70137 Regulation of Bdkrb2 10 0.27 5.45 4.62 5.00
138 INT118565 Gene_expression of Ddit3 35 0.75 23.62 4.32 5.00
139 INT113926 Positive_regulation of Localization of Bdnf 7 0.56 3.15 4.25 5.00
140 INT174277 Positive_regulation of Positive_regulation of Gopc 23 0.33 8.08 3.73 5.00
141 INT15002 Regulation of Gfap 17 0.37 5.34 3.61 5.00
142 INT100384 Regulation of SNRNP70 24 0.60 11 3.56 5.00
143 INT14281 Gene_expression of Hspa5 44 0.63 34.19 3.31 5.00
144 INT35009 Binding of CSAD 12 0.41 10.74 3.21 5.00
145 INT107514 Positive_regulation of Akr1b1 6 0.70 7.64 3.21 5.00
146 INT152961 Negative_regulation of Gene_expression of Aqp4 13 0.59 10.01 2.92 5.00
147 INT195978 Gene_expression of Hsp90b1 26 0.65 11.28 2.88 5.00
148 INT164116 Negative_regulation of 1190002H23Rik 33 0.51 18.73 2.71 5.00
149 INT153492 Gene_expression of Gmcl1 44 0.65 15.77 2.56 5.00
150 INT81262 Positive_regulation of Phlda2 9 0.43 3.76 2.47 5.00
151 INT9887 Negative_regulation of Gene_expression of Ptgs1 7 0.42 2.94 2.3 5.00
152 INT51869 Negative_regulation of Dmd 24 0.52 10.4 2.18 5.00
153 INT156180 Positive_regulation of Gene_expression of SNRNP70 14 0.49 4.54 2.13 5.00
154 INT66082 Regulation of CSAD 5 0.27 4.72 1.99 5.00
155 INT140171 Binding of Aqp4 7 0.36 11.63 1.98 5.00
156 INT141166 Positive_regulation of Gene_expression of Ddit3 15 0.56 10.32 1.92 5.00
157 INT190480 Positive_regulation of Localization of Ros1 11 0.34 8.29 1.81 5.00
158 INT17885 Negative_regulation of YWHAZ 6 0.56 2.74 1.58 5.00
159 INT118559 Positive_regulation of Hspa5 20 0.61 15.66 1.45 5.00
160 INT89209 Negative_regulation of Binding of Ptgs1 6 0.06 2.7 1.39 5.00
161 INT28674 Negative_regulation of Gene_expression of Pla2g1b 3 0.40 2.36 1.16 5.00
162 INT30731 Positive_regulation of Gene_expression of GGT1 8 0.49 6.55 1.15 5.00
163 INT228770 Gene_expression of amd 16 0.57 21.49 1.05 5.00
164 INT173747 Regulation of Positive_regulation of Esr1 4 0.37 4.85 0.95 5.00
165 INT39369 Binding of NARFL 14 0.29 16.7 0.93 5.00
166 INT272414 Positive_regulation of Positive_regulation of NARFL 9 0.37 12.88 0.84 5.00
167 INT173082 Positive_regulation of Binding of VEGFA 20 0.48 11.16 0.79 5.00
168 INT172959 Gene_expression of Lefty1 4 0.21 5.15 0.76 5.00
169 INT272415 Negative_regulation of Gene_expression of NARFL 14 0.34 17.62 0.73 5.00
170 INT161778 Regulation of Gene_expression of Esr1 13 0.51 9.46 0.73 5.00
171 INT146505 Positive_regulation of Regulation of Gfap 4 0.44 1.98 0.7 5.00
172 INT287127 Gene_expression of Omd 6 0.39 1.63 0.67 5.00
173 INT157378 Gene_expression of PDR 14 0.53 11.46 0.64 5.00
174 INT164113 Negative_regulation of Negative_regulation of 1190002H23Rik 10 0.51 3.98 0.62 5.00
175 INT283110 Localization of Dag1 5 0.73 3.14 0.61 5.00
176 INT173748 Phosphorylation of Esr1 11 0.77 5.7 0.55 5.00
177 INT190479 Positive_regulation of 1190002H23Rik 6 0.07 5.64 0.53 5.00
178 INT11824 Negative_regulation of GGT1 3 0.57 1.39 0.53 5.00
179 INT155033 Gene_expression of Phlda2 18 0.30 9.45 0.5 5.00
180 INT9020 Binding of Tsv 2 0.25 1.28 0.48 5.00
181 INT140144 Binding of 1190002H23Rik 4 0.05 2.69 0.47 5.00
182 INT222077 Regulation of Hsp90b1 9 0.37 4.78 0.45 5.00
183 INT17239 Binding of Vwa2 5 0.01 3.46 0.44 5.00
184 INT154748 Positive_regulation of Gene_expression of Hspa5 11 0.44 7.66 0.44 5.00
185 INT32177 Negative_regulation of Sptbn1 2 0.14 0.89 0.43 5.00
186 INT340829 Positive_regulation of Arsi 1 0.02 1.76 0.39 5.00
187 INT340830 Binding of Arsi 1 0.01 1.66 0.37 5.00
188 INT200373 Binding of Omd 7 0.34 7.03 0.34 5.00
189 INT297602 Positive_regulation of Tsv 3 0.07 3.36 0.33 5.00
190 INT272272 Positive_regulation of Gene_expression of NARFL 17 0.40 18.85 0.31 5.00
191 INT202373 Transcription of Ddit3 6 0.62 5.52 0.29 5.00
192 INT118490 Regulation of CNOT4 2 0.02 1.18 0.27 5.00
193 INT273474 Positive_regulation of Gene_expression of Lefty1 1 0.01 1.61 0.26 5.00
194 INT181738 Positive_regulation of Localization of Gtf3a 4 0.02 2.46 0.25 5.00
195 INT215850 Regulation of Ddit3 5 0.50 6.15 0.25 5.00
196 INT263573 Negative_regulation of Gmcl1 3 0.20 1.7 0.23 5.00
197 INT283105 Positive_regulation of Gene_expression of Dag1 1 0.67 1.19 0.17 5.00
198 INT322766 Regulation of GSS 2 0.06 0.89 0.16 5.00
199 INT164111 Positive_regulation of Gene_expression of 1190002H23Rik 4 0.43 0.61 0.12 5.00
200 INT284514 Regulation of Regulation of PF4 1 0.20 1.19 0.12 5.00
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