D:Right Ventricular Dysfunction

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pChart

Disease Term
Synonyms Dysfunction Right Ventricular, Dysfunctions Right Ventricular, Right Ventricular Dysfunctions, VENTRICULAR DYSFUNCTIONS RIGHT
Documents 88
Hot Single Events 15
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Right Ventricular Dysfunction. They are ordered first by their relevance to Right Ventricular Dysfunction and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT230723 ERVW-1 Positive_regulation of Gene_expression of EDN1 1 0.00 1.95 0 34.48
2 INT256209 AVP Regulation of PVR 1 0.06 0.99 0 13.68
3 INT213071 IL6 Positive_regulation of Gene_expression of CRP 4 0.52 6.58 1.68 5.00
4 INT230734 Negative_regulation of Binding of EDNRA and Pah 1 0.02 3.26 0.61 5.00
5 INT230735 Binding of EDNRA and Pah 1 0.02 3.22 0.6 5.00
6 INT222284 Negative_regulation of Casp1 Negative_regulation of Il18 1 0.01 0.79 0.46 5.00
7 INT222283 Negative_regulation of Casp1 Negative_regulation of Il1a 1 0.00 0.78 0.46 5.00
8 INT230724 EDN1 Positive_regulation of EDNRA 3 0.24 4.12 0.39 5.00
9 INT239839 IL18 Positive_regulation of TNF 1 0.11 1.08 0.09 5.00
10 INT222295 Binding of CPP and Cebpz 1 0.00 0.73 0.05 5.00
11 INT256210 NPPB Regulation of PVR 1 0.24 1.14 0 5.00
12 INT256211 NPPB Regulation of PDAP1 1 0.28 1.14 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Right Ventricular Dysfunction. They are ordered first by their pain relevance and then by number of times they were reported in Right Ventricular Dysfunction. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT131788 Positive_regulation of NPPB 87 0.67 86.1 8.81 99.72
2 INT44683 Positive_regulation of Cyb5r4 12 0.30 6.54 1.41 99.44
3 INT32783 Gene_expression of Pah 33 0.60 30.55 6.86 98.64
4 INT9552 Positive_regulation of TNNI3 209 0.70 128.67 19.15 98.40
5 INT27813 Regulation of CENPJ 12 0.29 14.26 0.99 97.80
6 INT16808 Binding of Scd1 5 0.00 7.18 0.33 97.56
7 INT33951 Regulation of TXNRD1 18 0.51 6.97 4.02 97.32
8 INT9084 Positive_regulation of Nppb 74 0.70 69.77 11.85 97.20
9 INT110039 Positive_regulation of Nppb 38 0.53 34.54 2.88 94.72
10 INT129534 Gene_expression of Nppb 19 0.58 23.68 1.6 94.72
11 INT89614 Positive_regulation of FABP3 12 0.50 10.16 1.75 90.92
12 INT22965 Positive_regulation of Pah 42 0.61 41.41 8.84 83.52
13 INT334907 Protein_catabolism of Nppb 2 0.56 8.28 0.22 83.36
14 INT199746 Gene_expression of REV1 17 0.33 9.53 0.05 82.72
15 INT9083 Gene_expression of Nppb 74 0.78 70.96 12.19 82.24
16 INT156685 Regulation of ASAP1 8 0.22 1.94 0.71 80.00
17 INT46714 Positive_regulation of TNNC1 76 0.67 75.99 6.66 79.60
18 INT131351 Positive_regulation of Gene_expression of Nppb 2 0.50 13.72 1.14 79.12
19 INT860 Regulation of ALB 48 0.60 25.11 8.95 78.76
20 INT546 Binding of ALB 311 0.48 85.98 60.14 77.00
21 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 77.00
22 INT19537 Negative_regulation of Binding of ALB 6 0.43 3.32 2.26 77.00
23 INT88806 Transcription of CUX1 3 0.69 1.45 0.5 74.92
24 INT76336 Negative_regulation of PDE5A 192 0.59 112.02 20.09 73.64
25 INT108978 Positive_regulation of CUX1 16 0.57 5.93 1.73 72.56
26 INT15514 Negative_regulation of Crp 275 0.59 194.6 64.86 70.92
27 INT14183 Negative_regulation of CPB1 5 0.41 3.53 0.53 70.92
28 INT3760 Positive_regulation of ALB 142 0.70 87.46 26.7 70.24
29 INT36616 Positive_regulation of Binding of ALB 8 0.67 3 2.07 69.48
30 INT147792 Gene_expression of COPD 230 0.70 287.13 24.1 69.20
31 INT2921 Positive_regulation of F8 53 0.59 41.56 8.56 66.76
32 INT239841 Regulation of Protein_catabolism of TNNI3 1 0.32 1.6 0.2 65.92
33 INT161376 Protein_catabolism of TNNI3 7 1.00 3.92 0.67 64.56
34 INT92050 Negative_regulation of CUX1 1 0.21 1.91 0.44 64.08
35 INT18025 Binding of Pah 32 0.45 30.72 7.93 60.32
36 INT61680 Positive_regulation of PVR 23 0.60 23.27 3.86 60.08
37 INT28929 Negative_regulation of PVR 22 0.57 16.64 1.07 57.12
38 INT15746 Negative_regulation of PDAP1 13 0.52 6.45 1.12 56.72
39 INT12618 Positive_regulation of IAPP 54 0.68 32.03 2.29 55.04
40 INT29651 Regulation of Pah 11 0.37 9.95 2.79 53.28
41 INT258990 Localization of Emb 1 0.21 0.98 0.21 52.56
42 INT258989 Binding of Emb 1 0.10 0.98 0.21 51.08
43 INT45168 Negative_regulation of ASAP1 23 0.58 10.15 2.44 49.44
44 INT43947 Localization of ASAP1 11 0.68 4.49 0.88 49.44
45 INT375 Positive_regulation of REN 293 0.70 152.46 47.55 48.40
46 INT3299 Positive_regulation of AGT 126 0.68 79.45 21.91 48.16
47 INT176892 Binding of MR1 36 0.32 15.55 2.58 38.24
48 INT55479 Localization of Epo 13 0.81 6.1 1.53 37.44
49 INT318168 Positive_regulation of Localization of Epo 1 0.01 1.54 0 37.44
50 INT5623 Positive_regulation of Nppa 174 0.70 69.96 52.33 36.60
51 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 32.48
52 INT5622 Gene_expression of Nppa 101 0.78 49.46 25.31 31.64
53 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 31.44
54 INT9085 Localization of Nppb 32 0.81 15.1 3.47 30.76
55 INT19316 Positive_regulation of Localization of Nppb 2 0.50 3.15 0.73 30.76
56 INT61685 Positive_regulation of Gene_expression of Pah 6 0.43 4.05 1.79 29.28
57 INT258991 Gene_expression of Emb 2 0.43 2.55 0.23 29.00
58 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 28.72
59 INT240127 Binding of Nppb 19 0.37 22.42 3.3 26.88
60 INT93003 Binding of CD40 28 0.47 20.25 7.13 24.28
61 INT268232 Phosphorylation of PTGIR 4 0.11 1.91 0.95 21.04
62 INT45753 Localization of CD40LG 45 0.79 32.31 5.28 16.44
63 INT51840 Positive_regulation of Localization of CD40LG 8 0.69 9.59 1.58 16.44
64 INT177643 Binding of CENPJ 12 0.36 8.59 0.22 14.96
65 INT18010 Positive_regulation of CD40LG 122 0.70 100.8 18.46 11.92
66 INT39468 Positive_regulation of hf 10 0.33 13.5 1.32 9.48
67 INT122364 Gene_expression of UCN 5 0.65 2.79 0.44 8.20
68 INT3679 Gene_expression of AVP 171 0.78 72.9 35.23 7.76
69 INT62950 Gene_expression of NPPB 73 0.75 65.91 6.54 7.56
70 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 5.00
71 INT16868 Gene_expression of Il6 807 0.78 499.48 256.57 5.00
72 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 5.00
73 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 5.00
74 INT48895 Gene_expression of Il10 333 0.78 221.2 138.52 5.00
75 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 5.00
76 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 5.00
77 INT170025 Gene_expression of Fig4 588 0.67 183.27 113.32 5.00
78 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 5.00
79 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
80 INT1635 Gene_expression of Vip 245 0.78 53.36 88.13 5.00
81 INT5617 Localization of Nppa 266 0.81 83.51 83.89 5.00
82 INT64636 Positive_regulation of Gene_expression of Nos2 242 0.70 147.52 79.53 5.00
83 INT5969 Gene_expression of Il1a 221 0.75 96.31 71.38 5.00
84 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
85 INT48952 Negative_regulation of Nos2 204 0.59 101.73 53.15 5.00
86 INT12345 Gene_expression of Il2 142 0.78 59.17 51.21 5.00
87 INT2604 Positive_regulation of Got1 223 0.70 154.78 49.51 5.00
88 INT11939 Negative_regulation of Il6 138 0.59 87.46 41.24 5.00
89 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 5.00
90 INT5620 Positive_regulation of Localization of Nppa 105 0.70 30.23 36.45 5.00
91 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 5.00
92 INT18893 Positive_regulation of CPP 81 0.69 38.03 34.33 5.00
93 INT15610 Localization of GOPC 223 0.65 68.26 28.7 5.00
94 INT22211 Positive_regulation of CYP3A4 110 0.70 22 28.27 5.00
95 INT10799 Localization of ENG 63 0.78 18.67 27.28 5.00
96 INT5966 Localization of Il1a 50 0.78 22.91 26.54 5.00
97 INT100861 Binding of CRP 179 0.48 175.2 26.45 5.00
98 INT69036 Gene_expression of IL18 99 0.77 77.92 25.95 5.00
99 INT76095 Positive_regulation of ISYNA1 117 0.55 79.73 25.86 5.00
100 INT2040 Positive_regulation of CYP2B6 95 0.69 34.3 25.6 5.00
101 INT23937 Gene_expression of EDNRA 103 0.65 55.63 24.67 5.00
102 INT171820 Localization of Fig4 144 0.65 27.38 20.88 5.00
103 INT125312 Positive_regulation of COPD 134 0.59 162.55 20.27 5.00
104 INT12265 Positive_regulation of IgG 168 0.63 104.89 19.76 5.00
105 INT74286 Regulation of Il10 42 0.44 28.06 19.44 5.00
106 INT87861 Gene_expression of Il18 33 0.78 30.44 18.42 5.00
107 INT70970 Binding of COPD 144 0.42 180.34 18.29 5.00
108 INT10187 Gene_expression of Il2ra 91 0.78 52.67 16.66 5.00
109 INT49532 Regulation of Gene_expression of Il6 43 0.61 25.8 14.99 5.00
110 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
111 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
112 INT32595 Positive_regulation of Gene_expression of Il2 30 0.70 6.55 12.56 5.00
113 INT8546 Positive_regulation of MUC16 99 0.69 74.98 11.26 5.00
114 INT9550 Gene_expression of TNNI3 113 0.78 86.79 10.56 5.00
115 INT12344 Negative_regulation of Gene_expression of Il2 28 0.59 15.53 10.23 5.00
116 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 5.00
117 INT10139 Positive_regulation of F13A1 64 0.56 44.75 9.69 5.00
118 INT87863 Positive_regulation of IL18 40 0.69 34.08 9.53 5.00
119 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 5.00
120 INT60436 Negative_regulation of COPD 76 0.37 84.22 9.08 5.00
121 INT102698 Binding of ACCS 54 0.42 66.73 9.06 5.00
122 INT9548 Gene_expression of CHKB 99 0.65 50.86 9.03 5.00
123 INT20205 Binding of IgG 108 0.46 66.68 8.57 5.00
124 INT56223 Positive_regulation of MPO 35 0.70 43 8.2 5.00
125 INT26462 Gene_expression of DNAH8 44 0.78 19.36 7.31 5.00
126 INT147793 Localization of COPD 70 0.64 89.01 7.3 5.00
127 INT32709 Negative_regulation of Hbb 30 0.54 18.27 6.97 5.00
128 INT3757 Positive_regulation of Gene_expression of ALB 45 0.69 23.73 6.85 5.00
129 INT78182 Positive_regulation of ACCS 43 0.43 46.39 6.78 5.00
130 INT34767 Gene_expression of PTGIR 36 0.42 14.79 6.69 5.00
131 INT81586 Negative_regulation of Casp1 11 0.57 6.55 6.45 5.00
132 INT49468 Negative_regulation of Pah 28 0.55 24.95 6.29 5.00
133 INT65265 Positive_regulation of Gene_expression of Col7a1 48 0.69 23.81 6.16 5.00
134 INT91657 Negative_regulation of IL18 20 0.48 15.97 6.12 5.00
135 INT19086 Negative_regulation of COL1A1 32 0.38 16.77 5.98 5.00
136 INT18677 Gene_expression of F3 50 0.65 30.86 5.86 5.00
137 INT71220 Positive_regulation of Casp1 15 0.38 10.23 5.84 5.00
138 INT22839 Gene_expression of F2 31 0.74 15.53 5.56 5.00
139 INT17056 Gene_expression of DLD 37 0.57 13.15 5.47 5.00
140 INT18872 Negative_regulation of Asap1 18 0.43 8.48 5.42 5.00
141 INT19541 Gene_expression of Ptgir 22 0.65 15.42 5.39 5.00
142 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 5.00
143 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 5.00
144 INT7298 Gene_expression of NPPA 35 0.70 18.23 4.76 5.00
145 INT246315 Localization of Ednra 22 0.15 2.73 4.64 5.00
146 INT45159 Regulation of Nppb 16 0.54 13.57 4.46 5.00
147 INT5619 Positive_regulation of Gene_expression of Nppa 21 0.70 11.95 4.41 5.00
148 INT17548 Negative_regulation of Serpine1 30 0.57 24.69 3.93 5.00
149 INT16408 Negative_regulation of Nppb 14 0.53 5.49 3.74 5.00
150 INT159472 Localization of NPPB 32 0.79 33.67 3.59 5.00
151 INT61087 Positive_regulation of Gene_expression of Il2ra 12 0.35 9.1 3.25 5.00
152 INT55002 Gene_expression of ASAP1 46 0.64 22.8 3.2 5.00
153 INT161812 Positive_regulation of PER1 17 0.56 5.64 2.93 5.00
154 INT10189 Negative_regulation of Gene_expression of Il2ra 8 0.32 8.05 2.91 5.00
155 INT22429 Positive_regulation of PDAP1 34 0.61 22.58 2.91 5.00
156 INT139562 Transcription of IL18 10 0.68 6.14 2.73 5.00
157 INT100014 Negative_regulation of Gene_expression of EDN1 17 0.42 7.85 2.71 5.00
158 INT92877 Gene_expression of PDE5A 35 0.76 17.1 2.7 5.00
159 INT97452 Positive_regulation of MOCS1 20 0.39 11.4 2.59 5.00
160 INT222289 Localization of Il18 4 0.30 3.24 2.58 5.00
161 INT35349 Gene_expression of CENPJ 52 0.57 25.36 2.54 5.00
162 INT5968 Positive_regulation of Localization of Il1a 4 0.65 1.36 2.42 5.00
163 INT18143 Gene_expression of Tbxas1 9 0.56 5.89 2.39 5.00
164 INT11580 Binding of Cebpz 8 0.40 7.16 2.19 5.00
165 INT118305 Negative_regulation of Gene_expression of IL18 7 0.39 6.52 2.05 5.00
166 INT103095 Binding of ISYNA1 10 0.28 6.17 2.03 5.00
167 INT98888 Negative_regulation of Gene_expression of Il18 3 0.43 1.72 2.02 5.00
168 INT92129 Positive_regulation of Gene_expression of F3 13 0.08 12.13 2.02 5.00
169 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 5.00
170 INT10976 Negative_regulation of ENPP3 13 0.42 5.11 1.92 5.00
171 INT49377 Negative_regulation of Scd1 11 0.49 9.84 1.88 5.00
172 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76 5.00
173 INT67604 Gene_expression of SERPINC1 14 0.67 11.47 1.72 5.00
174 INT176888 Positive_regulation of MR1 29 0.67 11.68 1.71 5.00
175 INT60749 Localization of IAPP 17 0.78 12.57 1.69 5.00
176 INT3818 Regulation of Apc 13 0.39 12.52 1.68 5.00
177 INT119346 Positive_regulation of PTGIR 9 0.58 6.2 1.61 5.00
178 INT22966 Negative_regulation of Positive_regulation of Pah 2 0.50 2.03 1.56 5.00
179 INT216932 Positive_regulation of Negative_regulation of Il6 3 0.38 4.88 1.55 5.00
180 INT93840 Gene_expression of TNNC1 15 0.57 10.07 1.54 5.00
181 INT11948 Negative_regulation of Gene_expression of Vip 9 0.43 2.8 1.54 5.00
182 INT35132 Gene_expression of PDAP1 18 0.52 9.05 1.5 5.00
183 INT18844 Binding of IAPP 11 0.36 11.01 1.45 5.00
184 INT60772 Negative_regulation of Ednrb 8 0.41 4.56 1.39 5.00
185 INT108423 Negative_regulation of Pde12 3 0.06 1.81 1.26 5.00
186 INT22235 Gene_expression of Eln 11 0.76 5.4 1.23 5.00
187 INT79598 Regulation of PDE5A 16 0.60 8.68 1.17 5.00
188 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12 5.00
189 INT99003 Regulation of Vcam1 7 0.41 6.91 1.04 5.00
190 INT41506 Localization of Ptgir 6 0.64 2.51 1.04 5.00
191 INT129971 Regulation of PVR 5 0.60 3.96 0.97 5.00
192 INT213306 Negative_regulation of Eras 2 0.09 2.5 0.94 5.00
193 INT191835 Gene_expression of Airn 10 0.66 4.83 0.9 5.00
194 INT70027 Positive_regulation of Gene_expression of C6orf25 10 0.62 7.21 0.83 5.00
195 INT36978 Localization of Pah 9 0.73 7.43 0.82 5.00
196 INT48909 Localization of DLD 9 0.63 3.37 0.75 5.00
197 INT22385 Positive_regulation of Ptgir 8 0.41 5.16 0.71 5.00
198 INT116653 Gene_expression of Eras 4 0.28 1.59 0.65 5.00
199 INT89616 Gene_expression of FABP3 9 0.78 5.35 0.62 5.00
200 INT213305 Binding of Eras 5 0.16 2.81 0.6 5.00
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