D:Strongyloidiasis

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Disease Term
Synonyms Anguilluliases, Anguilluliasis, Strongyloidiases, STRONYLOIDOSIS, Threadworm Infection, Threadworm Infections
Documents 76
Hot Single Events 28
Hot Interactions 5

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Strongyloidiasis. They are ordered first by their relevance to Strongyloidiasis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT195196 IL13 Positive_regulation of Gene_expression of IGHE 1 0.06 1.79 0 83.00
2 INT195200 IL10 Positive_regulation of Gene_expression of IGHE 1 0.07 1.78 0 83.00
3 INT195197 Gene_expression of IL9 Positive_regulation of Gene_expression of IGHE 1 0.05 1.77 0 83.00
4 INT195198 Gene_expression of IL5 Positive_regulation of Gene_expression of IGHE 1 0.09 1.76 0 83.00
5 INT195199 Gene_expression of IL4 Positive_regulation of Gene_expression of IGHE 1 0.08 1.76 0 83.00
6 INT195195 IL4 Regulation of Gene_expression of IGHE 1 0.10 0.68 0.04 66.20
7 INT226371 IL18 Positive_regulation of IL4 4 0.05 2.49 0.79 5.00
8 INT300551 TBX21 Regulation of Hand1 2 0.10 0.44 0.48 5.00
9 INT300751 Binding of IGHE and Hand2 1 0.04 0 0.34 5.00
10 INT300727 IL25 Positive_regulation of IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
11 INT300732 IL33 Positive_regulation of IL13 1 0.00 0 0.34 5.00
12 INT300728 IL33 Positive_regulation of IL4 1 0.00 0 0.33 5.00
13 INT300729 IL18 Positive_regulation of IL13 1 0.00 0 0.33 5.00
14 INT300742 Stat6 Regulation of Hand2 1 0.01 0.06 0.3 5.00
15 INT300752 GATA3 Regulation of Hand2 1 0.01 0.06 0.3 5.00
16 INT177961 Binding of CCR3 and CCL11 1 0.04 0.73 0.26 5.00
17 INT177957 CCL11 Regulation of Binding of IL5 and CCL11 1 0.01 0.71 0.25 5.00
18 INT177960 Binding of IL5 and CCL11 1 0.03 0.71 0.25 5.00
19 INT177962 IL4 Positive_regulation of VCAM1 1 0.02 0.97 0.2 5.00
20 INT300753 Binding of Cd28 and Positive_regulation of Transcription of IL13 1 0.00 0 0.17 5.00
21 INT304169 Il33 Positive_regulation of Gene_expression of Itgam 1 0.02 1.18 0.15 5.00
22 INT300731 IL10 Negative_regulation of Gene_expression of IGHE 1 0.03 0.23 0.13 5.00
23 INT304172 Il5 Positive_regulation of Bcl2l1 1 0.02 0.91 0.05 5.00
24 INT199041 AGRP Regulation of IGHE 1 0.00 1.39 0.03 5.00
25 INT304170 Binding of Apaf1 and Positive_regulation of Casp9 1 0.01 0.51 0 5.00
26 INT304175 IL1B Positive_regulation of Gene_expression of Vcam1 1 0.02 0.96 0 5.00
27 INT304135 Binding of CEL and Positive_regulation of CASP8 1 0.00 0.52 0 5.00
28 INT285291 TNF Positive_regulation of Gene_expression of Vcam1 2 0.10 3.1 0 5.00
29 INT304176 Binding of IL1B and Il13 1 0.00 0.96 0 5.00
30 INT304167 Il4 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.94 0 5.00
31 INT304168 Binding of Gata1 and Sfpi1 1 0.08 0.07 0 5.00
32 INT177958 IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
33 INT304171 Il13 Positive_regulation of Gene_expression of Vcam1 1 0.04 0.89 0 5.00
34 INT304174 Binding of IL1B and Il4 1 0.00 0.96 0 5.00
35 INT177959 Positive_regulation of IGHE Positive_regulation of TNF 1 0.03 2.23 0 5.00
36 INT279131 LTF Positive_regulation of CALR 1 0.03 2.39 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Strongyloidiasis. They are ordered first by their pain relevance and then by number of times they were reported in Strongyloidiasis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT59792 Gene_expression of STH 14 0.75 15.2 0.61 99.92
2 INT69157 Gene_expression of IL5 127 0.77 102.58 26.81 99.80
3 INT69160 Positive_regulation of IL5 41 0.65 36.04 7.75 99.80
4 INT35164 Negative_regulation of IGHE 96 0.58 76.3 9.74 99.70
5 INT8798 Positive_regulation of Csrp1 61 0.69 63.86 14.14 98.40
6 INT85130 Regulation of IL5 14 0.27 8.37 3.55 96.96
7 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 96.56
8 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 96.56
9 INT171021 Negative_regulation of IL5 18 0.41 14.74 3.39 95.80
10 INT270687 Negative_regulation of Regulation of IL5 2 0.25 0.91 0.07 95.80
11 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 94.76
12 INT3988 Positive_regulation of Gene_expression of IGHE 98 0.68 91.46 9.61 94.76
13 INT56301 Positive_regulation of IL4 68 0.56 54.51 18.65 93.76
14 INT195194 Regulation of Positive_regulation of Ighm 1 0.05 0.86 0 93.44
15 INT3795 Positive_regulation of Ighm 46 0.68 22.43 6.47 93.44
16 INT21940 Positive_regulation of CALR 15 0.40 17.42 0.95 92.72
17 INT18007 Positive_regulation of C6orf25 23 0.66 14.98 1.95 92.48
18 INT1118 Gene_expression of C6orf25 73 0.77 47.24 9.1 90.64
19 INT3796 Gene_expression of Ighm 130 0.77 69.61 13.78 90.64
20 INT3797 Positive_regulation of Gene_expression of Ighm 16 0.47 9.4 2.01 90.64
21 INT132586 Negative_regulation of Hand2 40 0.30 26.58 9.28 90.16
22 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 89.04
23 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 86.88
24 INT701 Localization of IGHE 87 0.80 40.5 10.62 86.80
25 INT73498 Gene_expression of IL13 117 0.44 83.85 32.26 80.16
26 INT60526 Gene_expression of IL10 449 0.78 292.71 107.84 80.16
27 INT75929 Gene_expression of IL9 61 0.43 24.71 16.17 80.16
28 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 80.16
29 INT270686 Gene_expression of Il7r 17 0.71 7.93 3.94 76.72
30 INT505 Positive_regulation of GPT 89 0.67 69.38 14.94 75.00
31 INT22387 Positive_regulation of GOLT1A 1 0.29 0.58 0.19 75.00
32 INT180141 Localization of SRA1 3 0.07 1.66 0.27 74.48
33 INT20380 Gene_expression of Il5 172 0.78 104.75 34.78 71.28
34 INT194380 Negative_regulation of Gene_expression of IL5 22 0.42 15.78 4.1 69.92
35 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 67.92
36 INT636 Binding of MRAP 54 0.48 40.36 18.77 66.08
37 INT25163 Positive_regulation of Gene_expression of IL2RA 8 0.45 5.37 1.71 62.80
38 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 55.48
39 INT132822 Localization of IL13 26 0.67 22.85 6.66 52.64
40 INT173505 Localization of Hand2 63 0.57 45.32 13.66 52.40
41 INT5056 Gene_expression of IFNG 216 0.78 137.52 74.57 50.00
42 INT25223 Positive_regulation of Gene_expression of IFNG 41 0.67 36.97 15.89 50.00
43 INT69156 Localization of IL5 21 0.68 14.95 5.37 50.00
44 INT9081 Positive_regulation of Positive_regulation of IGHE 5 0.42 7.13 1 46.96
45 INT3758 Gene_expression of ALB 326 0.78 184.65 38.75 29.60
46 INT113101 Gene_expression of Ccl11 41 0.76 22.36 5.47 8.08
47 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 5.00
48 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 5.00
49 INT5059 Positive_regulation of TNF 1050 0.70 896.51 322.81 5.00
50 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
51 INT6481 Binding of TNF 624 0.48 510.2 214.82 5.00
52 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 5.00
53 INT5116 Gene_expression of IL2 670 0.78 291.13 146.69 5.00
54 INT65600 Positive_regulation of Casp3 376 0.70 198.44 128.03 5.00
55 INT20374 Gene_expression of Il4 515 0.76 306.15 114.12 5.00
56 INT11587 Gene_expression of CSF2 645 0.78 544.38 93.89 5.00
57 INT170332 Gene_expression of IFN1@ 477 0.75 275.21 69.65 5.00
58 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
59 INT169926 Positive_regulation of Gopc 416 0.46 157.8 58.67 5.00
60 INT31116 Gene_expression of Casp3 192 0.78 78.21 57.43 5.00
61 INT20382 Gene_expression of Hand2 211 0.66 142.26 51.05 5.00
62 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 5.00
63 INT110023 Negative_regulation of Mapk14 127 0.59 84.27 45.42 5.00
64 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 5.00
65 INT73502 Positive_regulation of IL10 154 0.69 124.87 43.5 5.00
66 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 5.00
67 INT77307 Gene_expression of Bcl2 399 0.77 319.77 38 5.00
68 INT63349 Gene_expression of PECAM1 199 0.75 166.03 36.76 5.00
69 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 5.00
70 INT54302 Positive_regulation of Gene_expression of Il4 126 0.68 86.18 30.75 5.00
71 INT34729 Positive_regulation of IFN1@ 233 0.67 128.04 30.38 5.00
72 INT10915 Gene_expression of ITGAM 164 0.78 92.42 29.78 5.00
73 INT65597 Negative_regulation of Casp3 69 0.59 39.19 29.32 5.00
74 INT15174 Gene_expression of Itgam 238 0.73 104.92 29.26 5.00
75 INT19856 Gene_expression of CD8A 240 0.75 147.86 26.39 5.00
76 INT73670 Gene_expression of Vcam1 128 0.78 123.79 24.96 5.00
77 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 5.00
78 INT8775 Binding of IGHE 167 0.48 102.61 23.54 5.00
79 INT74423 Localization of IL10 91 0.80 61.6 22.95 5.00
80 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 5.00
81 INT96156 Gene_expression of Cd40 144 0.77 56.95 21.7 5.00
82 INT5328 Positive_regulation of CD4 191 0.69 133.43 21.31 5.00
83 INT62042 Positive_regulation of Gene_expression of IL4 67 0.56 42.05 20.39 5.00
84 INT3952 Negative_regulation of ALB 116 0.59 72.18 18.35 5.00
85 INT112017 Regulation of Hand2 77 0.36 62.23 18.04 5.00
86 INT80755 Gene_expression of CD40 88 0.75 53.68 17.86 5.00
87 INT104045 Regulation of Hand1 65 0.35 51.32 16.26 5.00
88 INT81627 Gene_expression of Fas 120 0.78 115.51 15.36 5.00
89 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 5.00
90 INT109511 Gene_expression of Bax 133 0.78 113.22 14.36 5.00
91 INT36263 Positive_regulation of CEL 53 0.69 34.88 12.87 5.00
92 INT69158 Localization of IL4 48 0.71 31.3 11.98 5.00
93 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 5.00
94 INT58904 Localization of TH1L 40 0.68 27.11 10.52 5.00
95 INT98130 Positive_regulation of CASP8 79 0.67 65.29 10.08 5.00
96 INT70134 Negative_regulation of TXK 124 0.23 81.96 9.59 5.00
97 INT85966 Gene_expression of Cd40lg 50 0.73 30.9 9.11 5.00
98 INT2241 Negative_regulation of CEL 56 0.58 29.32 8.83 5.00
99 INT8903 Gene_expression of IFNA2 58 0.71 38.23 8.68 5.00
100 INT81444 Positive_regulation of Gene_expression of Vcam1 40 0.70 46.38 8.58 5.00
101 INT2971 Regulation of IGHE 42 0.61 28.81 7.87 5.00
102 INT78226 Gene_expression of Mbp 43 0.75 22.14 7.79 5.00
103 INT91667 Localization of IL12A 39 0.74 25.51 7.36 5.00
104 INT58365 Gene_expression of LTF 51 0.78 44.14 7.25 5.00
105 INT93003 Binding of CD40 28 0.47 20.25 7.13 5.00
106 INT93046 Positive_regulation of Gene_expression of Hand2 27 0.47 24.54 7.01 5.00
107 INT11747 Positive_regulation of IL2RA 22 0.67 16.55 6.95 5.00
108 INT17049 Localization of CD4 57 0.75 35.33 6.89 5.00
109 INT126984 Positive_regulation of Gene_expression of Il5 29 0.69 20.61 6.72 5.00
110 INT16068 Gene_expression of SERPINB1 27 0.60 20.51 6.56 5.00
111 INT73499 Positive_regulation of IL13 23 0.39 20.03 6.53 5.00
112 INT304151 Gene_expression of Siglec5 2 0.74 17.33 6.03 5.00
113 INT8803 Gene_expression of IL3 32 0.78 21.06 6.01 5.00
114 INT69153 Positive_regulation of Gene_expression of IL5 22 0.32 23.59 5.7 5.00
115 INT53684 Negative_regulation of Gene_expression of ITGAM 23 0.59 14.36 5.66 5.00
116 INT56299 Transcription of IL4 15 0.64 10.2 5.44 5.00
117 INT171562 Regulation of IL4 19 0.36 12.12 5.33 5.00
118 INT177526 Negative_regulation of Il5 17 0.36 11.13 5.31 5.00
119 INT81796 Binding of AGRP 62 0.36 37.19 5.3 5.00
120 INT117004 Gene_expression of Sfpi1 21 0.75 15.95 5.29 5.00
121 INT62041 Negative_regulation of Gene_expression of IGHE 37 0.58 37.86 5.27 5.00
122 INT30738 Negative_regulation of Gene_expression of ALB 32 0.59 19.01 5.04 5.00
123 INT2725 Positive_regulation of FCER2 23 0.69 23.08 4.7 5.00
124 INT82354 Positive_regulation of PECAM1 25 0.34 22.93 4.69 5.00
125 INT87322 Binding of ITGAL 23 0.47 15.73 4.68 5.00
126 INT87632 Positive_regulation of Gene_expression of PECAM1 32 0.45 29.47 4.66 5.00
127 INT18995 Binding of CEL 23 0.47 14.46 4.5 5.00
128 INT108342 Negative_regulation of EPHB2 18 0.57 9.48 4.46 5.00
129 INT141665 Gene_expression of AGRP 83 0.67 43.43 4.24 5.00
130 INT73503 Positive_regulation of Gene_expression of IL13 16 0.37 14.6 4.23 5.00
131 INT48518 Gene_expression of ANPEP 51 0.78 22.88 4.18 5.00
132 INT72385 Phosphorylation of Shc1 11 0.52 1.62 4.1 5.00
133 INT123752 Regulation of Bax 19 0.60 16.45 4 5.00
134 INT112692 Localization of Bax 31 0.80 20.97 3.98 5.00
135 INT4464 Localization of CEL 21 0.80 8.09 3.88 5.00
136 INT172677 Gene_expression of SHE 65 0.59 25.86 3.85 5.00
137 INT146946 Gene_expression of Lyn 16 0.76 8.9 3.75 5.00
138 INT170528 Negative_regulation of Gene_expression of CD4 25 0.41 17.98 3.6 5.00
139 INT40712 Gene_expression of EPX 9 0.78 5.93 3.6 5.00
140 INT70919 Binding of Il4 19 0.36 6.58 3.59 5.00
141 INT9999 Regulation of Gene_expression of IGHE 32 0.60 15.75 3.53 5.00
142 INT73500 Regulation of IL13 12 0.36 10.37 3.53 5.00
143 INT89966 Negative_regulation of Fas 26 0.58 24.83 3.5 5.00
144 INT188355 Binding of Cd28 25 0.34 8.29 3.38 5.00
145 INT85971 Positive_regulation of Gene_expression of Cd40lg 14 0.66 7.61 3.29 5.00
146 INT64234 Regulation of Bcl2 41 0.54 31.88 3.16 5.00
147 INT114276 Gene_expression of Nr4a1 20 0.77 7.71 3.14 5.00
148 INT98226 Negative_regulation of Cd79a 5 0.49 3.99 2.66 5.00
149 INT28815 Gene_expression of Ighd 18 0.65 11.02 2.48 5.00
150 INT27230 Gene_expression of LTBR 10 0.75 8.57 2.34 5.00
151 INT118871 Negative_regulation of JAK2 15 0.57 11.4 2.16 5.00
152 INT84018 Gene_expression of RNASE3 15 0.65 8.27 2.12 5.00
153 INT98225 Regulation of Il5 8 0.45 5.07 2.06 5.00
154 INT221431 Negative_regulation of FOXP3 8 0.40 9.92 1.98 5.00
155 INT38268 Positive_regulation of BEST1 16 0.17 14.54 1.93 5.00
156 INT129240 Positive_regulation of Stat6 6 0.67 1.96 1.92 5.00
157 INT36018 Negative_regulation of Gene_expression of CD8A 12 0.42 6.66 1.85 5.00
158 INT102843 Negative_regulation of PDC 5 0.57 4.26 1.82 5.00
159 INT20377 Gene_expression of Il3 8 0.65 0.82 1.77 5.00
160 INT40713 Negative_regulation of EPX 7 0.37 2.21 1.73 5.00
161 INT98984 Localization of RNASE3 5 0.47 4.51 1.68 5.00
162 INT186269 Binding of Il13 9 0.39 7.7 1.64 5.00
163 INT163613 Transcription of CSF2 16 0.60 12.98 1.62 5.00
164 INT113340 Phosphorylation of JAK2 17 0.78 5.69 1.6 5.00
165 INT114279 Positive_regulation of Nr4a1 9 0.59 3.37 1.59 5.00
166 INT114862 Gene_expression of BEST1 16 0.65 12.14 1.53 5.00
167 INT114270 Gene_expression of Plscr1 6 0.47 1.33 1.49 5.00
168 INT100672 Transcription of Hand2 9 0.42 2.84 1.47 5.00
169 INT152223 Binding of BEST1 10 0.29 6.67 1.46 5.00
170 INT78704 Binding of CCL11 10 0.37 11.38 1.44 5.00
171 INT179169 Transcription of IL13 11 0.15 4.22 1.37 5.00
172 INT254666 Positive_regulation of Map2k2 37 0.56 23.85 1.35 5.00
173 INT112695 Negative_regulation of Protein_catabolism of Bax 3 0.36 1.72 1.3 5.00
174 INT102200 Gene_expression of Nr4a2 9 0.72 3.69 1.28 5.00
175 INT167056 Gene_expression of CALR 29 0.75 20.05 1.25 5.00
176 INT170979 Transcription of IL5 7 0.33 5.08 1.21 5.00
177 INT112693 Protein_catabolism of Bax 5 0.74 3.17 1.2 5.00
178 INT114272 Regulation of Gene_expression of Nr4a1 5 0.45 1.82 1.14 5.00
179 INT67156 Binding of ITGA4 6 0.14 2.63 1.03 5.00
180 INT117002 Negative_regulation of Sfpi1 16 0.58 9.72 1 5.00
181 INT147113 Binding of LTF 14 0.29 18.24 0.98 5.00
182 INT79862 Negative_regulation of Gene_expression of ANPEP 3 0.38 1.67 0.98 5.00
183 INT73450 Gene_expression of Pilra 7 0.05 2.87 0.97 5.00
184 INT123948 Positive_regulation of Plscr1 4 0.42 1.02 0.93 5.00
185 INT228727 Transcription of Il5 4 0.27 5.13 0.9 5.00
186 INT81794 Regulation of AGRP 12 0.39 4.94 0.9 5.00
187 INT160830 Gene_expression of Siglece 6 0.39 2.37 0.85 5.00
188 INT177965 Negative_regulation of Transcription of IL4 3 0.25 2.11 0.78 5.00
189 INT150165 Gene_expression of MTTP 21 0.75 10.1 0.73 5.00
190 INT94300 Negative_regulation of Gene_expression of Mbp 6 0.44 1.79 0.7 5.00
191 INT177972 Transcription of IL3 2 0.20 1.81 0.66 5.00
192 INT304148 Gene_expression of Csf2ra 1 0.36 2.09 0.65 5.00
193 INT122196 Gene_expression of TAL1 5 0.47 2.07 0.63 5.00
194 INT147554 Gene_expression of Birc2 11 0.75 10.93 0.6 5.00
195 INT162801 Localization of CALR 7 0.73 8.69 0.6 5.00
196 INT188754 Localization of AGRP 15 0.74 8.88 0.6 5.00
197 INT177968 Negative_regulation of Transcription of CSF2 3 0.37 2.8 0.55 5.00
198 INT73524 Positive_regulation of Ear1 7 0.27 4.82 0.54 5.00
199 INT82051 Negative_regulation of RNASE3 8 0.32 6.81 0.53 5.00
200 INT125821 Regulation of Positive_regulation of IGHE 6 0.40 5.38 0.53 5.00
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