D:Susac Syndrome

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pChart

Disease Term
Synonyms Retinocochleocerebral Vasculopathies, RETINOCOCHLEOCEREBRAL VASCULOPATHY, SUSAC S SYNDROME, Susacs Syndrome, Syndrome Susac, SYNDROME SUSAC S, Vasculopathies Retinocochleocerebral, VASCULOPATHY RETINOCOCHLEOCEREBRAL
Documents 11
Hot Single Events 2
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Susac Syndrome. They are ordered first by their relevance to Susac Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT274094 EDN1 Positive_regulation of AGT 1 0.16 0.95 0.2 71.60
2 INT54972 Binding of EDNRA and EDNRB 7 0.52 3.31 0.97 5.00
3 INT178097 Binding of EDN1 and EDNRA 7 0.21 5.97 0.62 5.00
4 INT274095 Binding of EDNRA and OPA1 1 0.12 0.65 0.04 5.00
5 INT274096 Binding of EDN1 and EDNRA Positive_regulation of Positive_regulation of EDN1 1 0.22 0.78 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Susac Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Susac Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT8662 Positive_regulation of EDN1 144 0.70 125.34 19.59 95.48
2 INT8661 Positive_regulation of Positive_regulation of EDN1 10 0.66 10.9 1.76 83.04
3 INT48766 Regulation of NOS1 73 0.61 37.01 24.59 73.24
4 INT10184 Regulation of EDN1 44 0.62 23.78 10.06 73.24
5 INT60776 Regulation of EDNRA 20 0.51 16.62 5.36 73.24
6 INT274098 Regulation of EDNRB 1 0.33 2.41 0.18 73.24
7 INT3777 Positive_regulation of NARFL 256 0.56 302.43 25.74 53.80
8 INT272274 Localization of NARFL 24 0.60 27.55 1.18 53.80
9 INT119523 Gene_expression of EDNRB 32 0.75 26.47 5.75 26.16
10 INT178127 Positive_regulation of Gene_expression of EDNRB 7 0.51 5.24 0.78 26.16
11 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 5.00
12 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 5.00
13 INT48767 Negative_regulation of NOS1 312 0.59 154.25 90.32 5.00
14 INT79060 Gene_expression of NOS2 116 0.78 69.25 34.84 5.00
15 INT8905 Gene_expression of EDN1 215 0.78 157.1 34.19 5.00
16 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 5.00
17 INT79061 Positive_regulation of NOS2 92 0.65 58.89 23.96 5.00
18 INT1981 Negative_regulation of NARFL 219 0.47 223.48 16.41 5.00
19 INT9191 Localization of EDN1 94 0.81 57.01 14.78 5.00
20 INT8904 Positive_regulation of Gene_expression of EDN1 66 0.70 65.4 14.42 5.00
21 INT21979 Negative_regulation of EDN1 52 0.58 24.65 12.55 5.00
22 INT70905 Positive_regulation of EDNRA 49 0.67 24.33 11.79 5.00
23 INT76091 Positive_regulation of NOS3 48 0.61 18.4 7.92 5.00
24 INT54978 Binding of EDNRA 36 0.41 14.97 7.86 5.00
25 INT89131 Negative_regulation of NOS2 20 0.58 9.68 6.56 5.00
26 INT11826 Positive_regulation of LDLR 62 0.62 45.09 6.21 5.00
27 INT70907 Negative_regulation of EDNRA 30 0.36 19.68 5.49 5.00
28 INT107386 Negative_regulation of AGTR1 37 0.55 35.94 5.15 5.00
29 INT272273 Gene_expression of NARFL 89 0.54 121.19 4.47 5.00
30 INT24883 Regulation of OPA1 14 0.45 9.73 3.44 5.00
31 INT5913 Binding of OPA1 12 0.41 9.33 2.92 5.00
32 INT3605 Negative_regulation of OPA1 14 0.38 10.88 2.84 5.00
33 INT49259 Regulation of Localization of EDN1 8 0.61 6.29 1.92 5.00
34 INT178130 Binding of EDNRB 12 0.36 6.18 1.84 5.00
35 INT139514 Localization of EDNRB 7 0.73 4.63 1.52 5.00
36 INT181639 Positive_regulation of Positive_regulation of NOS3 8 0.41 3.72 1.41 5.00
37 INT49258 Negative_regulation of Positive_regulation of EDN1 10 0.43 7.24 1.12 5.00
38 INT99966 Negative_regulation of Positive_regulation of NARFL 13 0.37 13.32 0.98 5.00
39 INT89288 Positive_regulation of Negative_regulation of NOS1 5 0.40 4.84 0.96 5.00
40 INT139515 Positive_regulation of EDNRB 15 0.67 10.35 0.93 5.00
41 INT272275 Regulation of Positive_regulation of NARFL 8 0.36 16.68 0.86 5.00
42 INT49256 Regulation of Positive_regulation of EDN1 2 0.45 2.5 0.65 5.00
43 INT139512 Positive_regulation of Localization of EDNRB 3 0.37 0.69 0.26 5.00
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