D:Temporomandibular Joint Syndrome

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Disease Term
Synonyms Clicking Jaw Syndrome, Costen S Complex, Costen S Syndrome, Costen Syndrome, Costens Syndrome, Joint Syndrome Temporomandibular, MANDIBULAR DYSFUNCTION, Myofascial Pain, Myofascial Pain Dysfunction Syndrome Temporomandibular Joint, Pain Dysfunction Syndrome, Snapping Jaw
Documents 9728
Hot Single Events 200
Hot Interactions 33

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Temporomandibular Joint Syndrome. They are ordered first by their relevance to Temporomandibular Joint Syndrome and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT156509 Il6 Regulation of Positive_regulation of Grin1 1 0.28 1.93 1.93 100.00
2 INT156508 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.22 0.98 0.98 100.00
3 INT156510 Nfkb1 Regulation of Positive_regulation of Grin1 1 0.03 0.98 0.98 100.00
4 INT148818 IL1B Regulation of Gene_expression of TNC 1 0.29 0.57 0.47 99.84
5 INT161482 Il1b Negative_regulation of TGFB1 1 0.45 1.17 0.76 99.68
6 INT161483 Slc7a12 Regulation of Gene_expression of TGFB1 1 0.14 1.21 0.77 99.68
7 INT161481 Slc7a12 Regulation of Gene_expression of Il1b 1 0.14 1.21 0.77 99.68
8 INT144299 Il1b Positive_regulation of Oprm1 1 0.42 0.4 0.74 99.60
9 INT162599 Wnt5a Regulation of Gene_expression of IL4I1 1 0.00 0.1 0.28 99.56
10 INT161485 Il1b Regulation of Gene_expression of TGFB1 1 0.47 1.21 0.77 99.50
11 INT91428 CD44 Positive_regulation of Binding of MMRN1 1 0.24 0.85 0.55 99.48
12 INT155406 Binding of Adrb2 and Ngf 1 0.05 0.39 0.53 97.96
13 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17 97.94
14 INT64718 IL1B Positive_regulation of Gene_expression of IL6 15 0.59 9.37 4.48 97.88
15 INT161484 Binding of TGFB1 and Il1b 1 0.37 1.16 0.73 97.36
16 INT146478 IL1B Positive_regulation of Gene_expression of HAS1 1 0.48 0.24 0.24 96.88
17 INT99304 Igf1 Positive_regulation of Gh1 1 0.44 0.39 0.39 96.40
18 INT124427 NPEPPS Positive_regulation of Protein_catabolism of COL7A1 1 0.00 0.56 0.84 94.32
19 INT146476 IL1B Regulation of Gene_expression of HAS1 1 0.30 0.35 0.4 90.40
20 INT352464 Gse1 Positive_regulation of Gene_expression of Slc1a3 1 0.05 1.55 1.83 89.68
21 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19 88.52
22 INT140985 Gli3 Regulation of Ihh 1 0.29 0.85 0.85 87.00
23 INT139342 Cts8 Regulation of Gene_expression of Tnf 1 0.06 0.96 0.13 86.72
24 INT352447 Gse1 Negative_regulation of Gene_expression of Calca 1 0.03 0.98 0.94 86.64
25 INT95431 Il1a Regulation of Mmp2 1 0.48 0.25 0.61 86.52
26 INT95435 Il1a Positive_regulation of Positive_regulation of Mmp3 1 0.59 0.25 0.61 86.52
27 INT95436 Il1a Positive_regulation of Mmp3 1 0.59 0.25 0.61 86.52
28 INT95432 Il1a Positive_regulation of Positive_regulation of Mmp9 1 0.37 0.25 0.6 86.52
29 INT298584 IL1B Regulation of Gene_expression of TNFRSF11B 1 0.22 0.7 0.4 86.00
30 INT95433 Mmp3 Regulation of Mmp2 1 0.17 0.24 0.6 83.08
31 INT114029 Binding of ALB and Mmp3 1 0.01 0.31 0.55 82.40
32 INT114028 Negative_regulation of Binding of ALB and Mmp3 1 0.01 0.31 0.55 82.40
33 INT95430 Mmp9 Positive_regulation of Mmp3 1 0.38 0.24 0.6 80.32
34 INT95434 Mmp9 Positive_regulation of Positive_regulation of Il1a 1 0.42 0.23 0.61 79.96
35 INT108687 Nfkb1 Regulation of Positive_regulation of Nos2 1 0.50 1.28 0.88 76.92
36 INT108686 Nfkb1 Regulation of Nos2 1 0.69 1.27 0.88 76.92
37 INT298588 IL1B Regulation of Gene_expression of CSF1 1 0.35 0.59 0.36 76.88
38 INT139339 Cts8 Negative_regulation of Gene_expression of Tnfrsf1b 1 0.08 1.3 0.14 76.36
39 INT86429 Binding of Hspb1 and Esr1 1 0.19 0.26 0.13 75.00
40 INT352454 Gse1 Negative_regulation of Gene_expression of Gfap 1 0.09 0.15 0.18 74.64
41 INT352453 Calca Positive_regulation of Trib3 1 0.00 0.8 1.08 73.64
42 INT352468 Calca Positive_regulation of Prkaca 1 0.11 0.8 1.08 73.64
43 INT139336 Il1b Regulation of Tnfrsf1a 1 0.27 1.3 0.14 73.20
44 INT139338 Cts8 Regulation of Tnfrsf1a 1 0.05 1.3 0.14 73.20
45 INT139346 Cts8 Regulation of Gene_expression of Tnfrsf1a 1 0.05 1.3 0.14 73.20
46 INT139347 Il1b Regulation of Gene_expression of Tnfrsf1a 1 0.27 1.3 0.14 73.20
47 INT104780 IL1B Positive_regulation of Transcription of IL6 1 0.40 0.07 0 69.00
48 INT87839 Binding of Cd74 and Dcn 1 0.36 0.21 0.13 67.84
49 INT139341 Positive_regulation of Il1b Positive_regulation of Tnfrsf1b 1 0.11 1.27 0.14 67.16
50 INT139344 Negative_regulation of Il1b Positive_regulation of Tnfrsf1b 1 0.10 1.26 0.14 66.60
51 INT60328 Il1b Positive_regulation of Tnf 2 0.29 1.84 0.62 66.28
52 INT139345 Il1b Positive_regulation of Tnfrsf1b 1 0.11 1.26 0.14 66.28
53 INT139337 Il1b Positive_regulation of Positive_regulation of Tnfrsf1b 1 0.12 1.26 0.14 66.28
54 INT139340 Il1b Positive_regulation of Positive_regulation of Tnf 1 0.09 1.26 0.14 66.28
55 INT139343 Il1b Positive_regulation of Nos2 1 0.09 1.26 0.14 66.28
56 INT103651 IL1B Positive_regulation of Gene_expression of IL8 6 0.78 1.23 0.98 65.28
57 INT135180 IL1B Positive_regulation of Gene_expression of TNFSF11 2 0.76 1.73 0.75 64.64
58 INT352462 Gse1 Positive_regulation of Gene_expression of Tnc 1 0.05 0.75 0.64 58.88
59 INT117203 Binding of IL1B and IL6 2 0.20 1.4 0.51 58.32
60 INT354235 Aif1 Regulation of P2ry12 1 0.20 0.49 0.45 50.00
61 INT55682 IL1B Positive_regulation of TIMP1 2 0.46 0.17 0.28 50.00
62 INT122216 IL1B Positive_regulation of CCL5 3 0.67 0.53 0.04 50.00
63 INT94426 CTS Positive_regulation of Gene_expression of TIMP2 1 0.04 0 0 50.00
64 INT94424 IL1B Negative_regulation of Negative_regulation of TIMP2 1 0.06 0 0 50.00
65 INT143438 HIF1A Regulation of Gene_expression of VEGFA 1 0.69 0.13 0 50.00
66 INT94425 IL1B Negative_regulation of Transcription of TIMP2 1 0.06 0 0 50.00
67 INT100424 Bcl2 Regulation of Pcbd1 1 0.14 0.06 0 50.00
68 INT127690 TNF Positive_regulation of Regulation of CCL5 1 0.33 0.17 0 50.00
69 INT122217 IL1B Positive_regulation of Gene_expression of CCL5 2 0.52 0.08 0 50.00
70 INT143439 Positive_regulation of HIF1A Regulation of Gene_expression of VEGFA 1 0.30 0.13 0 50.00
71 INT100425 Bax Regulation of Pcbd1 1 0.06 0.06 0 50.00
72 INT137933 TGFB3 Regulation of Tgfb1 1 0.00 0 0 49.44
73 INT137934 IGF1 Regulation of Tgfb1 1 0.00 0 0 49.44
74 INT137935 Tgfb1 Regulation of TGFB3 1 0.00 0 0 49.44
75 INT137929 IGF1 Regulation of TGFB3 1 0.00 0 0 49.44
76 INT352460 Gse1 Negative_regulation of Gene_expression of Mapk14 1 0.02 0.05 0.03 32.80
77 INT352445 Gse1 Positive_regulation of Gene_expression of Dusp1 1 0.06 0.41 0.34 22.72
78 INT352465 Dusp1 Negative_regulation of Gene_expression of Mapk14 1 0.03 1.09 0.92 8.40
79 INT352456 Dusp1 Negative_regulation of Mapk14 1 0.03 1.31 1.03 7.84
80 INT352444 Dusp1 Negative_regulation of Phosphorylation of Mapk14 1 0.03 1.09 0.91 7.84
81 INT102130 Il6 Positive_regulation of Gene_expression of Crp 4 0.05 7.39 1.91 5.00
82 INT151849 IL10 Negative_regulation of Gene_expression of IL8 4 0.14 3.26 1.54 5.00
83 INT209881 Binding of TNFRSF11B and TNFSF11 8 0.36 8.92 0.86 5.00
84 INT182636 Binding of TNFSF11 and TNFRSF11A 16 0.29 17.5 0.84 5.00
85 INT187290 Binding of HEY1 and Gtf3a 1 0.00 6.18 0.83 5.00
86 INT190788 Adcy8 Positive_regulation of Adcy1 1 0.23 0.77 0.77 5.00
87 INT239488 Spna1 Negative_regulation of Gene_expression of Timp1 1 0.00 0.94 0.62 5.00
88 INT352459 Gse1 Regulation of Gene_expression of Tnc 1 0.05 0 0.6 5.00
89 INT252869 Binding of Trpv1 and Phax 2 0.01 0.18 0.6 5.00
90 INT352463 Gse1 Regulation of Gene_expression of Dusp1 1 0.07 0 0.59 5.00
91 INT239489 Spna1 Negative_regulation of Timp1 1 0.00 0.89 0.57 5.00
92 INT352972 IL4 Negative_regulation of Gene_expression of IL8 1 0.07 1.01 0.43 5.00
93 INT352986 IL10 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
94 INT352985 IL4 Negative_regulation of Gene_expression of Il6 1 0.01 1 0.43 5.00
95 INT352970 IL4 Negative_regulation of Positive_regulation of TH1L 1 0.01 0.91 0.4 5.00
96 INT224423 Binding of TNFRSF11B and TNFRSF11A 3 0.19 2.36 0.37 5.00
97 INT333886 Binding of Lep and Positive_regulation of Gene_expression of Nos2 1 0.39 0.73 0.29 5.00
98 INT333887 Binding of Lep and Positive_regulation of Gene_expression of Il1 1 0.17 0.73 0.29 5.00
99 INT352452 Calca Regulation of Gene_expression of Tnc 1 0.04 0 0.28 5.00
100 INT218936 Dusp1 Negative_regulation of Ephb1 2 0.03 0.89 0.28 5.00
101 INT352448 Gse1 Regulation of Tnc 1 0.03 0 0.28 5.00
102 INT352458 Dusp1 Regulation of Gene_expression of Tnc 1 0.07 0 0.28 5.00
103 INT352461 Calca Regulation of Gene_expression of Slc1a3 1 0.03 0 0.27 5.00
104 INT352451 Gse1 Regulation of Slc1a3 1 0.01 0 0.27 5.00
105 INT352443 Gse1 Regulation of Dusp1 1 0.03 0 0.27 5.00
106 INT352455 Gse1 Regulation of Gene_expression of Slc1a3 1 0.04 0 0.27 5.00
107 INT352449 Dusp1 Regulation of Gene_expression of Slc1a3 1 0.05 0 0.27 5.00
108 INT352457 Gse1 Regulation of Calca 1 0.02 0 0.27 5.00
109 INT352466 Calca Regulation of Gene_expression of Dusp1 1 0.04 0 0.27 5.00
110 INT333889 Lep Regulation of Col7a1 1 0.04 0.41 0.2 5.00
111 INT333888 Lep Regulation of Localization of GAG 1 0.68 0.38 0.19 5.00
112 INT181928 RLN1 Positive_regulation of TIMP1 1 0.00 0.1 0.17 5.00
113 INT352450 Tnc Regulation of Trib3 1 0.00 0.22 0.13 5.00
114 INT181929 GOPC Regulation of Gene_expression of TIMP1 1 0.00 0 0.12 5.00
115 INT352467 Dusp1 Negative_regulation of Mapk8 1 0.02 0.23 0.12 5.00
116 INT303966 Lep Regulation of Il1 2 0.09 0.41 0.1 5.00
117 INT333885 Lep Positive_regulation of Il1 1 0.17 0.05 0.03 5.00
118 INT292882 Binding of S100A12 and TP63 1 0.06 0.51 0 5.00
119 INT298585 TNFSF11 Positive_regulation of ACP5 1 0.16 0.09 0 5.00
120 INT298589 TNFRSF11B Regulation of IL1B 1 0.05 0 0 5.00
121 INT319042 Negative_regulation of Binding of Fgf7 and Fig4 1 0.07 0.2 0 5.00
122 INT298586 PTGER2 Regulation of Gene_expression of TNFSF11 1 0.06 0 0 5.00
123 INT298587 TNFSF11 Regulation of IL1B 1 0.18 0 0 5.00
124 INT298583 PTGER2 Regulation of Gene_expression of TNFRSF11B 1 0.04 0.1 0 5.00
125 INT319043 Binding of Fgf7 and Fig4 1 0.06 0.26 0 5.00
126 INT298582 IL1B Regulation of Gene_expression of TNFSF11 1 0.46 0 0 5.00
127 INT298581 PTGER2 Regulation of Gene_expression of CSF1 1 0.06 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Temporomandibular Joint Syndrome. They are ordered first by their pain relevance and then by number of times they were reported in Temporomandibular Joint Syndrome. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 100.00
2 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 100.00
3 INT58061 Gene_expression of Trpv1 1117 0.78 451.54 637.59 100.00
4 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 100.00
5 INT48955 Gene_expression of Nos2 753 0.78 403.87 208.08 100.00
6 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 100.00
7 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 100.00
8 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 100.00
9 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89 100.00
10 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 100.00
11 INT48953 Positive_regulation of Nos2 486 0.70 239.85 131.87 100.00
12 INT99163 Positive_regulation of Cd14 18 0.49 16.02 7.91 100.00
13 INT5307 Regulation of Tnf 87 0.62 78.71 43.4 100.00
14 INT81251 Gene_expression of Trpv2 78 0.78 28.27 41.76 100.00
15 INT164229 Gene_expression of LECT1 8 0.67 3.08 0.96 100.00
16 INT5337 Negative_regulation of Npy 87 0.59 19.6 46.75 100.00
17 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 100.00
18 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 100.00
19 INT92821 Positive_regulation of Gene_expression of Cd14 15 0.66 9.82 4.5 100.00
20 INT130029 Positive_regulation of Fcgr3a 1 0.27 1.79 1.02 100.00
21 INT99865 Binding of Trpv2 4 0.48 1.13 2.25 100.00
22 INT14714 Negative_regulation of NPY 10 0.58 4.41 4.52 100.00
23 INT55824 Negative_regulation of Positive_regulation of Gabrd 5 0.59 1.56 2.88 100.00
24 INT97152 Protein_catabolism of COL1A1 11 0.74 8.03 2.3 100.00
25 INT87836 Localization of Dcn 3 0.68 0.6 0.62 100.00
26 INT70503 Regulation of Gene_expression of Nos2 71 0.62 44 24.01 100.00
27 INT157359 Gene_expression of LOC685654 1 0.00 0.52 0.49 100.00
28 INT49437 Gene_expression of OAP 25 0.54 20.12 7.34 100.00
29 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 100.00
30 INT48593 Positive_regulation of NOS1 420 0.68 226.15 114.71 100.00
31 INT62663 Negative_regulation of ABCA12 1 0.41 0.88 0.7 100.00
32 INT129956 Gene_expression of MMP13 145 0.72 60.48 26.98 100.00
33 INT129962 Positive_regulation of Gene_expression of MMP13 41 0.65 20.74 8.54 100.00
34 INT58930 Negative_regulation of RAC1 14 0.55 7.55 1.4 100.00
35 INT35652 Negative_regulation of Casp8ap2 1 0.36 0.55 0.82 99.98
36 INT14737 Gene_expression of FN1 117 0.78 78.74 18.99 99.96
37 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 99.96
38 INT11406 Positive_regulation of Localization of CALCA 49 0.70 20.64 42.8 99.96
39 INT67611 Positive_regulation of Pparg 39 0.69 18.33 13.23 99.90
40 INT55908 Gene_expression of Ngfr 74 0.78 34.46 28.8 99.88
41 INT5200 Gene_expression of Fos 3083 0.78 894.43 1639.02 99.84
42 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 99.84
43 INT5202 Positive_regulation of Gene_expression of Fos 1163 0.70 319.28 684 99.84
44 INT123779 Positive_regulation of MMP13 42 0.65 24.3 12.45 99.84
45 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 99.84
46 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.84
47 INT93947 Regulation of Gene_expression of Timp1 5 0.25 5.04 3.42 99.84
48 INT3441 Regulation of Localization of Abat 117 0.38 8.67 87.59 99.84
49 INT116282 Gene_expression of Mmp13 83 0.75 45.4 20.18 99.84
50 INT141253 Regulation of Transcription of Trpv1 7 0.62 3.54 3.62 99.84
51 INT140190 Gene_expression of Ddr2 4 0.77 1.89 1.3 99.84
52 INT140191 Positive_regulation of Gene_expression of Mmp13 25 0.67 13.47 9.71 99.84
53 INT20624 Regulation of Gene_expression of TNC 5 0.60 2.49 0.87 99.84
54 INT5591 Regulation of Gene_expression of Fos 425 0.62 129.06 265.78 99.84
55 INT140188 Positive_regulation of Gene_expression of Ddr2 4 0.69 1.54 1.3 99.84
56 INT82878 Gene_expression of Ccl2 201 0.78 164.95 101.35 99.84
57 INT157204 Localization of TNFRSF10B 3 0.53 1.12 0.25 99.84
58 INT64202 Positive_regulation of Trpv1 643 0.70 249.66 397.42 99.82
59 INT48933 Gene_expression of Mapk3 93 0.75 44.39 37.92 99.82
60 INT10536 Gene_expression of Trib3 67 0.66 27.08 21.58 99.82
61 INT9233 Negative_regulation of Gene_expression of IL1B 114 0.59 56.99 41.82 99.80
62 INT115481 Gene_expression of CDSN 6 0.10 2.53 1.03 99.80
63 INT9234 Negative_regulation of Gene_expression of IL6 171 0.59 101.61 53.15 99.80
64 INT144274 Gene_expression of Cav3 28 0.78 3.21 2.47 99.78
65 INT68913 Gene_expression of Cd14 55 0.76 38.99 15.67 99.78
66 INT86698 Gene_expression of Cav1 38 0.78 16.37 11.75 99.78
67 INT96937 Gene_expression of Mmp9 191 0.75 150.3 56.01 99.76
68 INT6484 Binding of IL1B 122 0.47 75.84 35.07 99.76
69 INT130032 Regulation of Gene_expression of Fcgr3a 1 0.33 2.94 1.74 99.76
70 INT130030 Gene_expression of Fcgr3a 1 0.42 2.91 1.72 99.76
71 INT32324 Gene_expression of Eda 20 0.75 6.43 4.66 99.76
72 INT83887 Gene_expression of HMOX2 10 0.77 7.99 3.85 99.76
73 INT89054 Positive_regulation of Gene_expression of Trpv1 156 0.70 90.78 102.03 99.72
74 INT144840 Negative_regulation of Gene_expression of Kcna4 2 0.55 3.13 2.6 99.72
75 INT1715 Positive_regulation of Nrm 51 0.70 24 47.53 99.72
76 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.72
77 INT70987 Binding of RAC1 14 0.37 12.14 2.13 99.72
78 INT116216 Negative_regulation of Gene_expression of Kcna5 4 0.43 3.11 2.64 99.72
79 INT144841 Regulation of Gene_expression of Kcna4 1 0.60 2.99 2.26 99.70
80 INT136720 Gene_expression of PRSS2 6 0.50 4.99 1.43 99.70
81 INT136719 Transcription of PRSS2 1 0.02 0.33 0.46 99.70
82 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 99.68
83 INT68369 Transcription of TNC 13 0.72 8.69 4.42 99.68
84 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.68
85 INT73913 Regulation of Gene_expression of Esr1 2 0.41 2.24 1.92 99.68
86 INT70265 Regulation of MRI1 42 0.39 30.95 14.18 99.68
87 INT65054 Positive_regulation of Nfkb1 285 0.70 149.33 126.73 99.68
88 INT65537 Positive_regulation of Positive_regulation of Nfkb1 52 0.67 30.6 26.35 99.68
89 INT54834 Gene_expression of Col2a1 48 0.72 13.5 9.41 99.68
90 INT79395 Gene_expression of Twist1 193 0.77 100.06 26.34 99.68
91 INT16621 Negative_regulation of Esr1 20 0.54 8.2 4.84 99.68
92 INT15769 Gene_expression of Il1b 146 0.78 114.51 75.35 99.68
93 INT58475 Localization of Rac1 12 0.75 5.94 3.2 99.68
94 INT69440 Gene_expression of ROS1 752 0.78 477.64 103.83 99.68
95 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 99.66
96 INT58102 Binding of MTRF1 4 0.08 6.39 3.05 99.66
97 INT3055 Binding of OLAH 9 0.28 7.14 3.99 99.66
98 INT162230 Binding of Gjb2 1 0.07 1.31 1.74 99.64
99 INT81486 Localization of MMP3 31 0.81 12.94 15.21 99.64
100 INT162231 Positive_regulation of Gjb2 1 0.09 0.67 0.85 99.64
101 INT162229 Positive_regulation of Binding of Gjb2 1 0.09 0.67 0.85 99.64
102 INT78579 Negative_regulation of P2rx3 23 0.59 10.13 10.78 99.62
103 INT91429 Binding of CD44 34 0.41 17.67 2.51 99.62
104 INT5235 Negative_regulation of TNF 924 0.59 772.91 331.98 99.60
105 INT149614 Localization of MMP13 13 0.81 6.12 3.65 99.60
106 INT14732 Positive_regulation of FN1 46 0.69 31.17 7.33 99.60
107 INT89519 Negative_regulation of COL1A2 10 0.36 6.26 2.17 99.60
108 INT109134 Gene_expression of PRG3 1 0.42 0.29 0.29 99.60
109 INT109133 Gene_expression of VCAN 52 0.75 53.11 0.84 99.60
110 INT5540 Positive_regulation of Oprm1 344 0.70 76.77 319.71 99.60
111 INT8794 Negative_regulation of Ppt1 35 0.57 6.44 14.52 99.58
112 INT19399 Gene_expression of Rf 43 0.36 33.39 13.53 99.58
113 INT5948 Regulation of Il1b 44 0.60 22.8 25.4 99.58
114 INT5228 Positive_regulation of Fos 934 0.70 209.8 503.87 99.56
115 INT130272 Gene_expression of Kcna4 12 0.75 9.25 7.61 99.56
116 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 99.56
117 INT70216 Gene_expression of HSPB1 8 0.78 4.81 0.64 99.56
118 INT21581 Gene_expression of IL4I1 9 0.24 4.21 1.37 99.56
119 INT11150 Positive_regulation of Dlst 31 0.51 9.01 6.63 99.54
120 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 99.54
121 INT72375 Phosphorylation of Mapk3 87 0.80 43.66 30.27 99.54
122 INT15326 Phosphorylation of Trib3 83 0.55 30.96 22.27 99.54
123 INT4369 Gene_expression of Ldha 157 0.76 88.12 22.45 99.54
124 INT125891 Localization of Mapkapk2 1 0.78 3.65 2.35 99.52
125 INT24068 Localization of Hspb1 6 0.78 6.11 2.75 99.52
126 INT6864 Positive_regulation of Gene_expression of Gfap 110 0.70 59.01 47.07 99.52
127 INT40436 Positive_regulation of Eda 21 0.70 8.09 6.15 99.52
128 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 99.52
129 INT14137 Localization of Oprm1 56 0.81 2.88 36.09 99.52
130 INT10597 Gene_expression of Cyp19a1 27 0.78 7.48 9.11 99.52
131 INT135760 Regulation of Gene_expression of Cyp19a1 2 0.62 1.15 5.81 99.52
132 INT166108 Localization of TNFSF10 5 0.64 3.58 0.33 99.52
133 INT24876 Gene_expression of CD34 172 0.78 91.02 12.39 99.48
134 INT19396 Regulation of Rac1 66 0.53 37.41 30.01 99.48
135 INT91432 Binding of MMRN1 23 0.36 9.79 2.95 99.48
136 INT71916 Gene_expression of TTN 9 0.75 1.69 0.97 99.48
137 INT86411 Negative_regulation of Negative_regulation of TNF 24 0.42 17.6 7.89 99.48
138 INT82650 Gene_expression of Bcl2 312 0.78 211.71 55.03 99.48
139 INT35811 Positive_regulation of Emg1 10 0.41 4.41 6.92 99.46
140 INT64076 Positive_regulation of Kcnma1 47 0.40 11.52 24.19 99.46
141 INT11659 Gene_expression of COL2A1 164 0.78 78.49 22.58 99.44
142 INT87549 Positive_regulation of Vps45 3 0.35 2.12 1.95 99.44
143 INT112080 Gene_expression of CTDSP2 1 0.52 1.07 0.72 99.44
144 INT27627 Binding of Rac1 41 0.41 22.88 13.68 99.44
145 INT48540 Gene_expression of Kcna5 37 0.77 14.04 16.07 99.44
146 INT69652 Regulation of P2rx3 26 0.61 17.17 15.4 99.42
147 INT112704 Positive_regulation of Hif1a 25 0.67 21.49 4.23 99.40
148 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 99.40
149 INT126223 Binding of Nos2 17 0.37 6 3.22 99.40
150 INT4891 Transcription of Calca 81 0.72 35.27 53.75 99.40
151 INT128516 Negative_regulation of Fmod 1 0.43 4.96 3.19 99.36
152 INT5587 Regulation of Fos 191 0.62 40.81 99.7 99.36
153 INT152340 Negative_regulation of Shox2 1 0.59 2.18 1.34 99.36
154 INT768 Positive_regulation of Oprl1 179 0.70 40.05 156.93 99.36
155 INT2065 Binding of BTG3 15 0.36 10.9 4.65 99.36
156 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 99.36
157 INT6481 Binding of TNF 624 0.48 510.2 214.82 99.34
158 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 99.34
159 INT141146 Gene_expression of Mmp13 18 0.38 8.61 5.54 99.32
160 INT91430 Positive_regulation of CD44 25 0.69 15.43 1.76 99.32
161 INT73918 Transcription of Esr1 21 0.66 8.74 3.12 99.32
162 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 99.30
163 INT25493 Gene_expression of TFPI 74 0.76 39.44 14.78 99.30
164 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 99.28
165 INT5842 Gene_expression of Gfap 372 0.78 153.71 127.71 99.28
166 INT133630 Negative_regulation of Gene_expression of ESR1 42 0.52 23.89 4.57 99.28
167 INT142120 Gene_expression of Runx2 45 0.77 15.76 2.55 99.24
168 INT97902 Gene_expression of AGGF1 17 0.11 13.45 2.51 99.24
169 INT120088 Gene_expression of Bmp4 37 0.73 13.89 1.73 99.24
170 INT142122 Regulation of Gene_expression of Bmp4 5 0.43 2.69 0.86 99.24
171 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22 99.24
172 INT34487 Localization of MMP2 56 0.81 31.41 23.61 99.24
173 INT16130 Binding of IGF1 67 0.48 27.43 2.95 99.22
174 INT6943 Positive_regulation of Gabrd 71 0.70 17.36 35.25 99.20
175 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 99.20
176 INT4941 Positive_regulation of Oprd1 345 0.70 74.26 304.41 99.20
177 INT61950 Regulation of Positive_regulation of Nos2 17 0.43 9.01 4.87 99.20
178 INT9158 Gene_expression of Tnf 722 0.78 522.01 277.68 99.16
179 INT51921 Gene_expression of Cpox 501 0.73 229.81 157.81 99.16
180 INT25123 Negative_regulation of COL7A1 42 0.58 19.98 5.96 99.16
181 INT3439 Localization of Abat 1017 0.78 112.39 727.06 99.16
182 INT6477 Gene_expression of IL1RN 213 0.77 114.69 58.62 99.16
183 INT87838 Gene_expression of Dcn 7 0.75 0.74 0.79 99.16
184 INT103775 Negative_regulation of Gene_expression of Dcn 1 0.41 0.19 0.24 99.16
185 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 99.14
186 INT49520 Gene_expression of P2rx3 121 0.78 61.15 49.24 99.12
187 INT56300 Negative_regulation of Gene_expression of TGFB1 13 0.41 4.87 3.5 99.12
188 INT95427 Positive_regulation of Mmp3 39 0.70 15.28 13.36 99.08
189 INT823 Negative_regulation of ESR1 144 0.58 63.72 22.52 99.08
190 INT18357 Gene_expression of TRPV1 825 0.78 307.11 382.81 99.08
191 INT108306 Positive_regulation of TNFRSF11B 28 0.60 12.74 4.46 99.08
192 INT50957 Negative_regulation of Il6 134 0.59 79.08 42.67 99.08
193 INT101657 Localization of ACTG2 1 0.27 0.58 0.52 99.04
194 INT57021 Positive_regulation of Gene_expression of Grin1 62 0.70 24.77 47.31 99.04
195 INT6482 Positive_regulation of Gene_expression of TNF 659 0.70 569.88 210 99.02
196 INT63361 Gene_expression of CD44 126 0.77 71.58 12.96 99.00
197 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 99.00
198 INT101992 Localization of VEGFA 413 0.81 258.23 36.15 99.00
199 INT52801 Regulation of Gene_expression of Tnf 55 0.62 48.74 26.59 98.96
200 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 98.96
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