D:Tendinopathy

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Disease Term
Synonyms TENDINITIDES, TENDINITIS, Tendinopathies, Tendinoses, TENDINOSIS, Tendonitides, Tendonitis
Documents 1568
Hot Single Events 184
Hot Interactions 12

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Tendinopathy. They are ordered first by their relevance to Tendinopathy and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT147863 Binding of CHAT and SLC18A3 1 0.34 0.8 0.14 97.36
2 INT285758 RETNLB Positive_regulation of Gene_expression of TIMP1 1 0.01 1.79 0.55 97.16
3 INT118659 Binding of GAPDH and IGKV1-5 1 0.21 0.09 0 88.08
4 INT118658 Binding of GAPDH and TRGV9 1 0.36 0.09 0 87.92
5 INT118660 Binding of COL1A1 and GAPDH 1 0.16 0.09 0 87.48
6 INT160541 Binding of BDNF and PSIP1 4 0.49 1.94 1.02 86.48
7 INT160540 Binding of NGF and PSIP1 2 0.29 1.43 1.12 86.48
8 INT160539 Binding of NGF and NGFR 1 0.06 0.46 0.17 86.32
9 INT160542 Binding of BDNF and NGFR 1 0.08 0.46 0.17 86.32
10 INT266006 Binding of COL5A2 and SGCG 1 0.00 0.89 0.23 85.96
11 INT266005 Binding of DIO3 and SGCG 1 0.00 0.86 0.22 85.96
12 INT266003 Binding of COL5A2 and DIO3 1 0.01 0.43 0.11 81.36
13 INT289791 Comp Regulation of Gene_expression of Col7a1 1 0.20 0.21 0 79.16
14 INT230019 Binding of HLA-B and ERAL1 1 0.00 2.23 1.1 73.84
15 INT238332 TNF Positive_regulation of Gene_expression of ADAMTS4 1 0.07 0.07 0.05 71.60
16 INT130851 Acan Positive_regulation of Gene_expression of Bgn 1 0.02 0.07 0 71.32
17 INT170992 Binding of FN1 and MMRN1 3 0.01 2.13 0.73 68.32
18 INT227928 Binding of MMRN1 and Lamb3 1 0.03 1.16 0.56 68.32
19 INT227911 Binding of VTN and MMRN1 1 0.01 1.16 0.56 68.32
20 INT227908 Binding of COL7A1 and MMRN1 1 0.00 1.11 0.53 68.32
21 INT339260 EPAS1 Positive_regulation of VEGFA 1 0.19 3.67 0 64.40
22 INT220155 IL1RN Regulation of IL1B 2 0.50 0.93 0.61 55.68
23 INT289793 Binding of Comp and Ecm1 1 0.05 2.5 0.12 50.00
24 INT289790 Binding of Col7a1 and Comp 1 0.14 1.2 0.12 50.00
25 INT289794 Binding of Comp and Fn1 1 0.07 2.59 0.12 50.00
26 INT289789 Comp Positive_regulation of Gene_expression of Rer1 1 0.55 0.8 0.03 50.00
27 INT106464 STK16 Positive_regulation of Gene_expression of MMP1 2 0.06 0.05 0 50.00
28 INT289795 Binding of COMP and Comp 1 0.02 0.99 0 50.00
29 INT289788 Binding of Comp and Scn8a 1 0.16 1.37 0 50.00
30 INT100274 IL1RN Negative_regulation of IL1B 5 0.53 1.79 1.65 45.04
31 INT269788 Binding of FN1 and TGFB1 1 0.00 0.29 0.1 39.24
32 INT234113 COL18A1 Negative_regulation of Phosphorylation of VEGFA 1 0.26 0.17 0.16 18.64
33 INT234112 Binding of VEGFA and COL18A1 1 0.21 0.16 0.15 18.64
34 INT227907 TNFRSF1B Regulation of TNF 1 0.01 0.41 0.36 12.36
35 INT227904 TNFRSF1A Regulation of TNF 1 0.01 0.41 0.36 12.36
36 INT148704 Binding of TNF and TNFRSF1A 5 0.44 3.3 2.09 5.00
37 INT61134 IL10 Negative_regulation of Gene_expression of IL1B 3 0.46 2.13 1.63 5.00
38 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27 5.00
39 INT333499 Binding of IGHE and PHB2 1 0.14 4.08 0.95 5.00
40 INT345303 MMP15 Positive_regulation of MMP13 1 0.00 1.18 0.58 5.00
41 INT345302 MMP15 Positive_regulation of MMP2 1 0.06 1.17 0.57 5.00
42 INT173555 TIMP1 Negative_regulation of MMP7 1 0.01 0 0.56 5.00
43 INT173556 TIMP1 Negative_regulation of MMP9 1 0.02 0 0.56 5.00
44 INT173557 TIMP1 Negative_regulation of MMP3 1 0.02 0 0.56 5.00
45 INT173554 TIMP1 Negative_regulation of MMP1 1 0.03 0 0.55 5.00
46 INT173553 TIMP1 Negative_regulation of MMP2 1 0.05 0 0.55 5.00
47 INT345308 Binding of ABCA1 and TIMP2 1 0.00 0.21 0.52 5.00
48 INT173597 Negative_regulation of Binding of MMP2 and Mmp13 1 0.14 0.83 0.48 5.00
49 INT345306 Binding of MMP14 and TIMP2 1 0.04 0.21 0.48 5.00
50 INT173595 Binding of MMP2 and Mmp13 1 0.12 0.83 0.48 5.00
51 INT345301 Binding of MMP14 and TIMP2 Positive_regulation of MMP2 1 0.02 0.21 0.48 5.00
52 INT173596 Binding of MMP3 and Mmp13 1 0.06 0.84 0.48 5.00
53 INT173598 Negative_regulation of Binding of MMP3 and Mmp13 1 0.06 0.84 0.48 5.00
54 INT345305 MMP14 Positive_regulation of MMP13 1 0.00 0.33 0.45 5.00
55 INT345304 MMP14 Positive_regulation of MMP2 1 0.08 0.2 0.45 5.00
56 INT227906 IL10 Regulation of Gene_expression of IL1B 1 0.07 0.57 0.38 5.00
57 INT227909 IL10 Regulation of Gene_expression of TNF 1 0.21 0.57 0.38 5.00
58 INT194859 IL1B Positive_regulation of Gene_expression of MMP13 2 0.52 0.86 0.33 5.00
59 INT227910 TNF Positive_regulation of Gene_expression of IL10 1 0.22 0.68 0.29 5.00
60 INT171050 Negative_regulation of F13A1 Regulation of PLG 1 0.02 0.55 0.28 5.00
61 INT171048 F13A1 Regulation of PLG 1 0.02 0.55 0.27 5.00
62 INT348924 Mmp1 Regulation of Gene_expression of Renbp 1 0.03 0.95 0.26 5.00
63 INT227903 TNF Positive_regulation of Gene_expression of ADAMTS5 1 0.01 0.56 0.24 5.00
64 INT171049 Binding of FAS and Positive_regulation of Gene_expression of CASP3 1 0.04 1.41 0.24 5.00
65 INT227905 IL10 Positive_regulation of Gene_expression of TIMP1 1 0.01 0.48 0.22 5.00
66 INT242094 Binding of ACLY and Pts 1 0.01 0 0.22 5.00
67 INT173558 CTSK Positive_regulation of Protein_catabolism of COL5A2 1 0.00 0.53 0.22 5.00
68 INT330514 Vegfa Positive_regulation of VEGFA 1 0.18 0.5 0.18 5.00
69 INT173599 Binding of MMP1 and Mmp1a 1 0.06 0.5 0.15 5.00
70 INT238331 PDGFA Regulation of Gene_expression of GOPC 1 0.04 0 0.14 5.00
71 INT238330 Binding of PDGFA and Regulation of Gene_expression of GOPC 1 0.06 0 0.14 5.00
72 INT238329 EGF Regulation of Negative_regulation of ADAMTS5 1 0.03 0 0.14 5.00
73 INT238338 Binding of EGF and Regulation of Gene_expression of GOPC 1 0.05 0 0.14 5.00
74 INT238333 Binding of PDGFA and Regulation of Gene_expression of ADAMTS1 1 0.06 0 0.14 5.00
75 INT238341 GOPC Regulation of Transcription of ADAMTS1 1 0.04 0 0.14 5.00
76 INT238337 EGF Regulation of Gene_expression of GOPC 1 0.03 0 0.14 5.00
77 INT238336 PDGFA Regulation of Negative_regulation of ADAMTS5 1 0.04 0 0.14 5.00
78 INT238334 GOPC Regulation of Transcription of ADAMTS5 1 0.04 0 0.14 5.00
79 INT238342 Binding of EGF and Regulation of Gene_expression of ADAMTS1 1 0.05 0 0.14 5.00
80 INT344135 Negative_regulation of Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 5.00
81 INT264399 Binding of IL1B and MMP13 1 0.39 0.08 0.13 5.00
82 INT264385 Binding of IL1B and MMP1 1 0.24 0.09 0.13 5.00
83 INT157602 Binding of COL1A1 and COL3A1 1 0.04 0 0.13 5.00
84 INT344134 Binding of Col7a1 and Lhyp 1 0.00 0.5 0.13 5.00
85 INT264397 MMP9 Regulation of Positive_regulation of MMP13 1 0.20 0.06 0.12 5.00
86 INT264389 MMP14 Regulation of Positive_regulation of MMP13 1 0.31 0.06 0.12 5.00
87 INT264403 NR1H4 Negative_regulation of IL1R2 1 0.04 0.09 0.12 5.00
88 INT264384 MMP3 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12 5.00
89 INT300570 Binding of IL1RN and SUGT1P2 1 0.01 0.43 0.12 5.00
90 INT264381 MMP3 Regulation of Positive_regulation of MMP13 1 0.21 0.06 0.12 5.00
91 INT264395 MMP9 Regulation of Positive_regulation of MMP1 1 0.13 0.06 0.12 5.00
92 INT264391 RXRG Negative_regulation of IL1R2 1 0.02 0.09 0.12 5.00
93 INT264411 MMP14 Regulation of Positive_regulation of MMP1 1 0.20 0.06 0.12 5.00
94 INT264409 MMP2 Regulation of MMP3 1 0.07 0.06 0.11 5.00
95 INT264400 MMP9 Regulation of MMP14 1 0.08 0.06 0.11 5.00
96 INT264398 MMP9 Regulation of MMP2 1 0.07 0.06 0.11 5.00
97 INT264406 MMP3 Regulation of MMP14 1 0.09 0.06 0.11 5.00
98 INT264402 MMP2 Regulation of MMP14 1 0.10 0.06 0.11 5.00
99 INT264388 MMP9 Regulation of MMP3 1 0.06 0.06 0.11 5.00
100 INT264390 MMP3 Regulation of MMP2 1 0.07 0.06 0.11 5.00
101 INT238340 IL1B Positive_regulation of Gene_expression of ADAMTS4 1 0.03 0.16 0.07 5.00
102 INT182943 Binding of DR1 and NR1H4 3 0.03 0.14 0.06 5.00
103 INT201973 Bmp7 Positive_regulation of ap 1 0.00 0.18 0.06 5.00
104 INT345307 CXCL12 Positive_regulation of Gene_expression of MMP15 1 0.00 2.5 0.05 5.00
105 INT264393 MMP1 Positive_regulation of Gene_expression of MMP13 1 0.29 0.14 0.04 5.00
106 INT264382 NR1H4 Positive_regulation of VDR 1 0.04 0.09 0.03 5.00
107 INT264396 NR1H4 Positive_regulation of THRA 1 0.01 0.09 0.03 5.00
108 INT312289 Binding of Col9a1 and Comp 1 0.09 1.38 0 5.00
109 INT264380 Binding of JUN and MMP13 1 0.05 0 0 5.00
110 INT252020 Binding of HLA-A and ELOVL1 1 0.01 1.41 0 5.00
111 INT354566 F2 Positive_regulation of PRNP 1 0.00 0.05 0 5.00
112 INT264407 Binding of DR1 and MMP13 1 0.08 0 0 5.00
113 INT264386 Binding of JUN and MMP1 1 0.03 0 0 5.00
114 INT264394 Binding of DR1 and JUN 1 0.01 0.07 0 5.00
115 INT312290 Binding of Col9a1 and Matn3 1 0.02 0.65 0 5.00
116 INT264401 Binding of DR1 and MMP1 1 0.05 0 0 5.00
117 INT339262 EPAS1 Positive_regulation of Gene_expression of VEGFA 1 0.14 0.23 0 5.00
118 INT264383 MMP1 Regulation of Binding of MMP13 1 0.28 0 0 5.00
119 INT264378 MMP1 Regulation of Transcription of MMP13 1 0.28 0 0 5.00
120 INT176543 Binding of Cd44 and Spp1 2 0.31 0.57 0 5.00
121 INT312291 Binding of Comp and Matn3 1 0.06 1.37 0 5.00
122 INT264404 MMP13 Regulation of Binding of MMP1 1 0.28 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Tendinopathy. They are ordered first by their pain relevance and then by number of times they were reported in Tendinopathy. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT193015 Positive_regulation of Gene_expression of EPAS1 6 0.32 8.77 0.21 100.00
2 INT153794 Gene_expression of Ctsk 51 0.77 24.99 7.28 100.00
3 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 99.96
4 INT200223 Positive_regulation of EPAS1 21 0.17 21.95 1.7 99.96
5 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 99.96
6 INT14740 Gene_expression of TGFB1 272 0.78 168.48 60.18 99.92
7 INT50674 Gene_expression of PTGS2 459 0.78 253.33 118.51 99.92
8 INT113671 Negative_regulation of Mmp3 26 0.49 6.33 7.88 99.80
9 INT183672 Gene_expression of EPAS1 37 0.35 28.68 0.72 99.76
10 INT153854 Positive_regulation of Ubl7 1 0.00 0.33 0.18 99.72
11 INT212565 Regulation of Adrm1 3 0.04 2.41 0.36 99.64
12 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 99.60
13 INT345320 Gene_expression of MMP23B 1 0.16 1.39 1 99.52
14 INT173581 Gene_expression of ADAM12 4 0.38 1.46 0.83 99.52
15 INT14733 Positive_regulation of Gene_expression of TGFB1 71 0.69 49.89 22.2 99.48
16 INT55135 Positive_regulation of Gene_expression of PTGS2 137 0.70 80.32 38.46 99.44
17 INT91527 Gene_expression of CTSK 38 0.78 22.21 7.42 99.44
18 INT278737 Positive_regulation of Transcription of Bmp2 1 0.47 1.4 0 99.40
19 INT27973 Gene_expression of ACOT1 31 0.65 15.7 3.15 99.34
20 INT136904 Gene_expression of SLC18A3 4 0.68 3.71 4.4 99.32
21 INT41728 Gene_expression of CHAT 65 0.75 42.19 12.73 99.32
22 INT130850 Transcription of Bgn 1 0.12 0.46 0.19 99.28
23 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 99.28
24 INT130847 Positive_regulation of Transcription of Bgn 1 0.10 0.23 0.09 99.28
25 INT1028 Positive_regulation of Lbp 102 0.69 67.86 46.05 99.20
26 INT48555 Binding of SP1 30 0.46 11.38 6.53 99.08
27 INT72370 Gene_expression of Timp1 82 0.65 57.52 24.16 99.08
28 INT22629 Positive_regulation of Shc2 2 0.55 0.99 0.26 99.08
29 INT79168 Binding of TNC 39 0.47 16.51 7.55 99.08
30 INT46999 Regulation of Positive_regulation of Shc2 1 0.36 0.35 0.1 99.08
31 INT150606 Binding of Col5a1 1 0.08 0.33 0.07 99.08
32 INT96424 Transcription of Bmp2 6 0.69 6.34 1.11 99.06
33 INT173591 Gene_expression of ADAMTS4 7 0.48 3.65 4.8 99.00
34 INT9094 Gene_expression of COL7A1 277 0.77 143.42 38.73 99.00
35 INT57274 Positive_regulation of Gene_expression of COL7A1 50 0.69 24.19 4.72 99.00
36 INT647 Gene_expression of SGCG 211 0.75 78.46 55.82 99.00
37 INT67890 Positive_regulation of Gene_expression of SGCG 26 0.67 9.91 6.41 99.00
38 INT77675 Gene_expression of Saa 40 0.58 43.37 18.69 98.96
39 INT147864 Regulation of SLC18A3 1 0.39 0.87 0.14 98.80
40 INT130849 Transcription of Acan 1 0.10 0.46 0.19 98.76
41 INT1912 Gene_expression of Calca 1152 0.78 453.25 739.84 98.76
42 INT105148 Positive_regulation of Gene_expression of TNC 6 0.50 6.45 1.8 98.64
43 INT158124 Gene_expression of COL5A2 136 0.69 72.3 12.44 98.60
44 INT158123 Negative_regulation of Gene_expression of COL5A2 19 0.46 15.27 2.23 98.60
45 INT15613 Negative_regulation of Ptgs2 160 0.59 71.08 65.08 98.54
46 INT110809 Gene_expression of Mmp1 20 0.75 18 14.49 98.52
47 INT93717 Gene_expression of Mmp3 85 0.78 33.95 24.89 98.52
48 INT123883 Positive_regulation of Gene_expression of Mmp3 16 0.60 4.42 3.74 98.52
49 INT110427 Gene_expression of Spp1 199 0.78 176.11 23.31 98.44
50 INT87374 Positive_regulation of CHAT 7 0.67 3.91 1.96 98.40
51 INT100626 Transcription of CHAT 4 0.51 1.94 0.69 98.40
52 INT30316 Regulation of CHAT 6 0.43 1.95 0.96 98.40
53 INT20632 Gene_expression of TNC 72 0.78 30.43 13.16 98.24
54 INT96423 Gene_expression of Bmp2 61 0.78 25.07 3.01 98.20
55 INT64113 Positive_regulation of Gene_expression of NOS1 110 0.60 71.03 29.72 98.16
56 INT161959 Gene_expression of PRDX2 2 0.65 1.38 0.2 98.16
57 INT81229 Binding of COL1A1 24 0.35 12.07 3.3 97.96
58 INT77676 Regulation of Gene_expression of Saa 4 0.29 3.2 1.61 97.94
59 INT180684 Regulation of Gene_expression of Mmp1 2 0.44 0.88 1.06 97.84
60 INT62124 Gene_expression of NOS1 444 0.78 218.08 114.85 97.76
61 INT97128 Localization of SPP1 32 0.80 21.75 4.02 97.72
62 INT37541 Gene_expression of SPP1 113 0.77 68.54 11.35 97.72
63 INT58192 Positive_regulation of MRI1 86 0.61 53.81 24.68 97.68
64 INT52722 Localization of RETNLB 54 0.38 48.63 27.98 97.60
65 INT147865 Positive_regulation of SLC18A3 1 0.43 0.8 0.14 97.36
66 INT23126 Regulation of HTR3A 10 0.60 5.42 4.81 96.92
67 INT51055 Positive_regulation of TIMP1 103 0.69 50.07 19.86 96.88
68 INT4893 Gene_expression of Tacr1 366 0.78 129.67 213.92 96.88
69 INT113672 Positive_regulation of Gene_expression of ITGB1 3 0.49 1.4 0.86 96.84
70 INT99069 Positive_regulation of Gene_expression of Mapk14 42 0.53 29.84 23.16 96.84
71 INT86293 Positive_regulation of Gene_expression of Mmp2 21 0.64 11.69 3.79 96.84
72 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 96.72
73 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 96.36
74 INT184431 Transcription of Adamts1 9 0.67 4.94 1.35 96.36
75 INT3038 Gene_expression of INS 1583 0.78 1174.16 107.01 96.28
76 INT91817 Positive_regulation of RETNLB 22 0.34 21.4 13.12 96.12
77 INT29496 Gene_expression of MMP3 136 0.75 49.49 41.78 95.92
78 INT102237 Positive_regulation of Gene_expression of MMP3 22 0.44 7.77 4.71 95.92
79 INT20631 Positive_regulation of CHKB 166 0.69 109.86 17.92 95.80
80 INT99070 Gene_expression of Mapk14 147 0.78 103.99 79.59 95.72
81 INT184305 Gene_expression of Comp 53 0.77 31.66 2.2 95.68
82 INT1758 Positive_regulation of Gene_expression of TIMP1 62 0.69 31.72 13.98 95.64
83 INT159989 Positive_regulation of Ctsk 17 0.69 10.51 2.25 95.60
84 INT1759 Gene_expression of TIMP1 267 0.77 133.87 59.29 95.36
85 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 95.36
86 INT121677 Gene_expression of Srms 6 0.59 3.15 1.61 95.36
87 INT100861 Binding of CRP 179 0.48 175.2 26.45 95.36
88 INT193016 Regulation of EPAS1 9 0.15 7.38 0.06 94.80
89 INT67912 Gene_expression of GRIN1 75 0.77 28.99 29.28 94.76
90 INT145305 Positive_regulation of Bmp2 12 0.69 8.65 0.24 94.56
91 INT8629 Positive_regulation of COL7A1 72 0.69 40.66 12.09 94.48
92 INT103246 Positive_regulation of Protein_catabolism of COL7A1 8 0.34 8.67 3.03 93.88
93 INT101034 Protein_catabolism of NPEPPS 8 0.65 2.08 3.12 93.72
94 INT102680 Protein_catabolism of COL7A1 49 0.69 34.68 15.78 93.52
95 INT77674 Positive_regulation of Gene_expression of Saa 11 0.36 11.92 6.09 93.44
96 INT121599 Negative_regulation of Gene_expression of RETNLB 7 0.21 9.28 8.8 93.44
97 INT2540 Negative_regulation of Calca 538 0.59 172.11 384.38 93.16
98 INT21956 Negative_regulation of Mmp7 12 0.34 7.32 5.34 93.04
99 INT65889 Gene_expression of RETNLB 73 0.34 60.98 38.3 92.84
100 INT173592 Binding of COL5A2 32 0.33 9.14 2.48 92.72
101 INT79261 Positive_regulation of Gene_expression of COL1A1 24 0.36 7.49 2.45 92.40
102 INT101104 Positive_regulation of Gene_expression of COL1A2 12 0.69 5.87 1.09 92.40
103 INT94453 Gene_expression of ITGB1 50 0.75 18.41 4.72 92.28
104 INT149138 Binding of PDX1 27 0.37 32.62 9.33 92.16
105 INT60066 Positive_regulation of NPEPPS 17 0.22 11.99 4.83 92.08
106 INT19963 Gene_expression of COL1A1 118 0.59 42.11 15.15 92.00
107 INT17024 Gene_expression of COL1A2 69 0.77 36.38 8.29 92.00
108 INT92823 Positive_regulation of Gene_expression of MMP1 65 0.68 25.69 14.31 92.00
109 INT9292 Positive_regulation of SGCG 93 0.67 35.13 23.48 91.84
110 INT196026 Positive_regulation of Gene_expression of Bmp2 14 0.69 3.19 0.35 91.72
111 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 91.72
112 INT185258 Gene_expression of Pou5f1 33 0.60 11.28 0.7 91.52
113 INT266250 Gene_expression of Lhb 28 0.64 10.75 4.66 91.48
114 INT48232 Gene_expression of MMP1 245 0.78 96.31 57.72 91.24
115 INT52692 Gene_expression of Ptgs2 160 0.78 85.06 55.73 90.88
116 INT86295 Gene_expression of Mmp2 114 0.76 73.68 24.25 90.80
117 INT22781 Binding of COL7A1 76 0.48 41.59 6.66 90.36
118 INT157605 Localization of COL3A1 3 0.80 0.55 0.29 90.28
119 INT5374 Gene_expression of Esr1 412 0.77 263.89 67.34 90.16
120 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 90.16
121 INT110810 Positive_regulation of Gene_expression of Mmp1 9 0.52 4.2 5.11 89.96
122 INT110811 Positive_regulation of Mmp1 5 0.60 2.96 2.83 89.96
123 INT5333 Gene_expression of NPEPPS 45 0.65 26.34 15.25 89.92
124 INT21579 Negative_regulation of Gene_expression of TIMP1 25 0.57 12.41 6.94 89.92
125 INT5332 Negative_regulation of Gene_expression of NPEPPS 11 0.04 7.79 4.29 89.92
126 INT79141 Regulation of Gene_expression of NPEPPS 3 0.01 2.95 1.61 89.92
127 INT145545 Transcription of TH 3 0.67 1.48 1.64 89.76
128 INT2543 Positive_regulation of Calca 787 0.70 331.13 592.08 89.44
129 INT142657 Regulation of Gene_expression of Col3a1 2 0.15 1.6 0.14 89.40
130 INT756 Gene_expression of C3 138 0.75 100.6 19.2 89.20
131 INT82871 Protein_catabolism of MMP1 13 0.96 10.71 4.09 89.16
132 INT12892 Negative_regulation of TIMP1 136 0.58 83.13 36.54 88.76
133 INT48235 Negative_regulation of NPEPPS 72 0.46 44.54 25.03 88.76
134 INT76611 Positive_regulation of Srms 5 0.59 3.21 3.04 88.64
135 INT6065 Localization of GRIN1 15 0.74 3.15 9.81 88.00
136 INT21582 Regulation of Gene_expression of TIMP1 20 0.61 12.39 4.77 87.76
137 INT66423 Binding of ELOVL1 52 0.40 61.63 5.16 87.48
138 INT312287 Gene_expression of Col9a1 1 0.21 2.94 0 87.08
139 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 87.00
140 INT115370 Gene_expression of PSIP1 22 0.65 9.45 5.68 86.48
141 INT129358 Gene_expression of ELOVL1 23 0.66 29.39 2.83 86.44
142 INT96492 Gene_expression of NGFR 24 0.00 12.3 4.59 86.32
143 INT159988 Localization of Ctsk 5 0.70 2.9 0.74 86.24
144 INT343783 Positive_regulation of Localization of Ctsk 1 0.45 0.46 0.09 86.24
145 INT86369 Positive_regulation of Gene_expression of PCNA 40 0.67 26.66 3.57 86.12
146 INT207474 Regulation of ADAMTS5 3 0.20 0.79 0.78 86.12
147 INT83200 Positive_regulation of Gene_expression of Nos3 48 0.70 24.75 12.99 86.12
148 INT111594 Positive_regulation of Gene_expression of NOSTRIN 20 0.32 8.69 5 86.12
149 INT22973 Gene_expression of Col3a1 22 0.42 15.85 4.32 85.88
150 INT238359 Localization of ADAMTS4 1 0.38 0.23 0.35 85.52
151 INT224620 Positive_regulation of Gene_expression of Ctsk 13 0.68 8.35 2.21 85.52
152 INT209423 Negative_regulation of Gene_expression of Ctsk 4 0.41 2.4 0.96 85.52
153 INT14246 Regulation of Positive_regulation of IL1B 7 0.44 3.04 1.77 85.48
154 INT56749 Gene_expression of PCNA 219 0.77 111.25 18.42 85.28
155 INT83199 Gene_expression of Nos3 193 0.78 100.72 51.57 85.28
156 INT62895 Gene_expression of NOSTRIN 51 0.75 28.8 10.68 85.28
157 INT75999 Gene_expression of BDNF 344 0.78 114.19 83.12 85.12
158 INT69215 Gene_expression of Col1a1 38 0.68 17.39 4.77 85.04
159 INT11381 Positive_regulation of IL1B 330 0.70 209.31 100.9 84.92
160 INT6473 Positive_regulation of Gene_expression of IL1B 204 0.70 117.23 50.86 84.92
161 INT62374 Gene_expression of NGF 158 0.78 77.87 76.45 84.76
162 INT52264 Gene_expression of IK 180 0.77 90.87 51.87 84.44
163 INT94082 Regulation of Gene_expression of IK 19 0.23 10.03 7.93 84.44
164 INT125897 Binding of Mmp9 3 0.36 2.36 1.32 84.28
165 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 84.24
166 INT212557 Negative_regulation of Gene_expression of MMP28 2 0.04 1.65 0.76 84.24
167 INT224327 Negative_regulation of EPAS1 5 0.09 4.29 0.08 84.24
168 INT176495 Gene_expression of MMP28 6 0.57 3.82 1.64 83.68
169 INT90910 Phosphorylation of Grin1 150 0.82 68.23 139.24 83.56
170 INT89791 Transcription of Mmp3 7 0.33 2.28 4.64 83.28
171 INT184223 Positive_regulation of Gene_expression of ADAMTS4 6 0.43 1.07 0.98 83.16
172 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 83.12
173 INT77677 Positive_regulation of Saa 30 0.49 33.19 11.18 83.04
174 INT2144 Localization of COL7A1 36 0.74 20.92 4.67 82.64
175 INT184306 Localization of Comp 2 0.69 5.1 0.12 82.36
176 INT289779 Regulation of Localization of Comp 1 0.39 1.29 0 82.36
177 INT125710 Negative_regulation of Mmp1 3 0.42 0.92 1.04 82.28
178 INT264008 Positive_regulation of Syncrip 2 0.50 1.71 1.63 82.08
179 INT118196 Gene_expression of ROM1 18 0.66 4.81 1.19 81.92
180 INT107606 Negative_regulation of MMP1 38 0.42 11.94 10.01 81.52
181 INT184310 Regulation of Comp 2 0.49 1.81 0.41 81.44
182 INT195616 Binding of ROM1 4 0.23 1.61 0.9 81.36
183 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 81.12
184 INT78024 Gene_expression of ACLY 73 0.75 59.15 18.54 80.76
185 INT155039 Gene_expression of ADAMTS5 23 0.67 7.85 3.22 79.88
186 INT184217 Regulation of Gene_expression of ADAMTS5 2 0.11 0.37 0.4 79.88
187 INT140503 Negative_regulation of Gene_expression of Mmp3 7 0.44 5.93 6.08 79.60
188 INT65245 Gene_expression of Nos3 121 0.78 98.14 41.56 79.52
189 INT141299 Negative_regulation of Gene_expression of Nos3 9 0.55 5.38 2.17 79.52
190 INT94454 Gene_expression of CD68 73 0.72 63.94 10.43 78.88
191 INT81578 Gene_expression of TRAP 25 0.72 9.75 2.82 78.88
192 INT65093 Gene_expression of ACP5 8 0.56 2.1 1.02 78.88
193 INT118665 Negative_regulation of Transcription of VCAN 1 0.42 0.08 0 78.60
194 INT130853 Transcription of DCN 2 0.67 0.42 0.26 78.28
195 INT187246 Gene_expression of ADAMTS1 3 0.24 1.17 1.84 78.24
196 INT238356 Positive_regulation of Gene_expression of ADAMTS1 1 0.16 0.15 0.32 78.24
197 INT27146 Negative_regulation of Regulation of Calca 4 0.43 1.18 2.9 78.20
198 INT60710 Gene_expression of Col7a1 217 0.78 113.2 35.2 78.16
199 INT9095 Regulation of Gene_expression of COL7A1 24 0.57 10.55 4.88 78.04
200 INT2649 Regulation of Calca 433 0.62 146.05 330.95 77.88
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