D:Thromboangitis Obliterans

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pChart

Disease Term
Synonyms Buerger Disease, BUERGER S DISEASE, BUERGERS DISEASE, Disease Buerger, Disease Buerger S, Presenile Gangrene, Presenile Gangrene Disorder, THROMBOANGIITIS OBLITERANS, Winiwarter Buerger Disease
Documents 90
Hot Single Events 14
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Thromboangitis Obliterans. They are ordered first by their relevance to Thromboangitis Obliterans and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT121713 WAS Positive_regulation of Gene_expression of SELP 1 0.30 0.49 0.63 73.04
2 INT245866 Binding of VEGFA and Fgf1 1 0.07 0.52 0.22 5.00
3 INT185756 Binding of ITIH4 and Cd4 2 0.05 1.22 0.04 5.00
4 INT245865 Binding of Cd34 and Ptprc 1 0.04 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Thromboangitis Obliterans. They are ordered first by their pain relevance and then by number of times they were reported in Thromboangitis Obliterans. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT86771 Positive_regulation of TAOK1 2 0.38 4.55 0.29 100.00
2 INT3987 Positive_regulation of IGHE 316 0.70 283.2 40.16 98.28
3 INT33105 Regulation of WAS 11 0.60 3.61 7.18 91.92
4 INT115613 Regulation of Gene_expression of ITGA2B 3 0.44 1.43 0.8 86.72
5 INT49142 Gene_expression of SELP 94 0.75 54.61 11.64 84.16
6 INT71161 Gene_expression of ITGB3 6 0.26 3.59 1.45 84.16
7 INT33739 Gene_expression of ITGA2B 25 0.75 8.19 3.6 84.16
8 INT49801 Positive_regulation of SELP 21 0.48 21.34 5.25 83.60
9 INT33133 Positive_regulation of ITGA2B 13 0.67 4.09 1.44 83.60
10 INT112380 Positive_regulation of ITGB3 2 0.49 0.84 0.69 83.60
11 INT23375 Binding of ENG 17 0.47 6.02 6.46 82.80
12 INT21682 Binding of CD34 18 0.47 13.19 1.47 82.80
13 INT164514 Binding of THY1 3 0.34 1.23 0.27 82.80
14 INT185738 Binding of Cd14 28 0.45 14.41 3.25 80.88
15 INT62711 Binding of HGF 27 0.31 15.23 2.08 74.44
16 INT62710 Gene_expression of HGF 160 0.78 88.27 26.14 73.92
17 INT63425 Positive_regulation of Gene_expression of SELP 23 0.67 15.34 3.48 72.88
18 INT121716 Positive_regulation of Gene_expression of ITGB3 1 0.13 0.49 0.63 72.88
19 INT74944 Positive_regulation of Gene_expression of HGF 31 0.70 17.69 6.68 61.60
20 INT185754 Negative_regulation of Binding of INCENP 5 0.03 2.01 0.13 61.40
21 INT8101 Binding of INCENP 42 0.31 16.2 6.68 61.08
22 INT89396 Phosphorylation of AKT1 225 0.82 111.66 19.61 25.00
23 INT42979 Positive_regulation of INSRR 47 0.32 12.24 14.38 25.00
24 INT12156 Positive_regulation of MET 43 0.67 17.75 12.64 25.00
25 INT61946 Positive_regulation of HGF 57 0.69 38.93 11.99 25.00
26 INT9398 Localization of MET 15 0.78 2.34 7.69 25.00
27 INT86805 Localization of HGF 49 0.71 28.48 6.35 25.00
28 INT33241 Localization of INSRR 10 0.10 1.24 3.08 25.00
29 INT126948 Phosphorylation of NEK3 3 0.09 1.89 0.22 25.00
30 INT5680 Gene_expression of Ngf 530 0.78 264.29 310.56 5.00
31 INT68684 Gene_expression of VEGFA 2371 0.78 1742.52 259.2 5.00
32 INT6488 Gene_expression of Tnf 484 0.78 339.61 191.58 5.00
33 INT19472 Gene_expression of Il1 554 0.76 419.75 175.35 5.00
34 INT7533 Gene_expression of Tlr4 720 0.78 343.22 121.57 5.00
35 INT16254 Positive_regulation of Gene_expression of Ngf 144 0.70 80.61 82.08 5.00
36 INT68682 Positive_regulation of VEGFA 640 0.70 454.14 81.65 5.00
37 INT79494 Positive_regulation of Gene_expression of VEGFA 577 0.70 442.94 69.73 5.00
38 INT4509 Gene_expression of IgG 426 0.76 293.69 56.64 5.00
39 INT66029 Negative_regulation of Tnf 100 0.59 84.28 48.16 5.00
40 INT25610 Positive_regulation of Gene_expression of Il1 136 0.67 104.43 43.86 5.00
41 INT91891 Gene_expression of Kit 268 0.78 158.89 22.67 5.00
42 INT20379 Localization of Il4 85 0.73 51.22 20.55 5.00
43 INT24209 Negative_regulation of Ifng 37 0.57 16.52 17.15 5.00
44 INT20622 Gene_expression of LDHA 107 0.76 77.97 16.3 5.00
45 INT4977 Binding of ITIH4 60 0.46 42.48 15.65 5.00
46 INT15172 Positive_regulation of Itgam 45 0.67 23.54 10.3 5.00
47 INT134625 Gene_expression of Kdr 116 0.71 53.13 10.09 5.00
48 INT24328 Gene_expression of Egf 97 0.75 59.65 9.42 5.00
49 INT18258 Negative_regulation of Thop1 20 0.56 1.6 8.61 5.00
50 INT76120 Gene_expression of Ptprc 102 0.59 30.42 7.02 5.00
51 INT32107 Gene_expression of PTPLA 14 0.47 8.06 6.76 5.00
52 INT9779 Gene_expression of Glb1 23 0.58 8.01 6.04 5.00
53 INT135172 Gene_expression of Hif1a 56 0.76 46.49 5.44 5.00
54 INT18681 Gene_expression of Thy1 80 0.71 38.8 5.23 5.00
55 INT28145 Binding of PAPPA 26 0.48 7.4 4.96 5.00
56 INT11261 Positive_regulation of PTPLA 3 0.50 4.4 3.74 5.00
57 INT31758 Positive_regulation of Egf 32 0.66 19.42 3.64 5.00
58 INT70885 Gene_expression of Pdgfb 48 0.67 42.27 3.19 5.00
59 INT91890 Positive_regulation of Kit 36 0.50 25.44 3.06 5.00
60 INT114702 Gene_expression of Fgf1 34 0.74 17.39 2.96 5.00
61 INT171117 Binding of Itgam 35 0.36 14.87 2.76 5.00
62 INT187454 Binding of Ptprc 34 0.38 9.66 2.54 5.00
63 INT132903 Gene_expression of Cd34 65 0.72 33.95 2.2 5.00
64 INT176088 Gene_expression of Tek 39 0.65 14.25 2.19 5.00
65 INT48888 Localization of Pbrgcsf1 11 0.29 5.04 2.05 5.00
66 INT182037 Localization of C3 10 0.68 6.69 1.54 5.00
67 INT135171 Positive_regulation of Gene_expression of Hif1a 15 0.68 16.95 1.51 5.00
68 INT20633 Positive_regulation of Gene_expression of LDHA 15 0.49 15.94 1.42 5.00
69 INT44529 Positive_regulation of Pdgfb 11 0.43 7.98 1.36 5.00
70 INT90938 Gene_expression of Eng 48 0.72 15.76 1.24 5.00
71 INT70886 Positive_regulation of Gene_expression of Pdgfb 13 0.45 12.57 1.17 5.00
72 INT200556 Regulation of Kdr 8 0.28 6.04 1.01 5.00
73 INT123154 Positive_regulation of Gene_expression of Thy1 7 0.53 4.34 0.86 5.00
74 INT171372 Positive_regulation of Gene_expression of Egf 16 0.66 9.82 0.84 5.00
75 INT185258 Gene_expression of Pou5f1 33 0.60 11.28 0.7 5.00
76 INT88317 Negative_regulation of Binding of ITIH4 6 0.36 4.46 0.69 5.00
77 INT194903 Binding of Cd34 12 0.37 5.06 0.56 5.00
78 INT184690 Transcription of Fgf1 6 0.51 1.97 0.55 5.00
79 INT187463 Positive_regulation of Gene_expression of Ptprc 9 0.44 2.8 0.42 5.00
80 INT70884 Localization of Pdgfb 8 0.35 6.22 0.42 5.00
81 INT176085 Regulation of Tek 6 0.37 3.36 0.4 5.00
82 INT245859 Positive_regulation of Epc1 2 0.05 1.85 0.35 5.00
83 INT114699 Positive_regulation of Gene_expression of Fgf1 4 0.32 2.21 0.29 5.00
84 INT245856 Regulation of Transcription of Fgf1 1 0.21 0.51 0.21 5.00
85 INT245863 Positive_regulation of Transcription of Fgf1 1 0.22 0.51 0.21 5.00
86 INT245860 Gene_expression of Itgb1 8 0.42 5.37 0.19 5.00
87 INT185753 Negative_regulation of YOD1 4 0.03 1.67 0.17 5.00
88 INT245861 Gene_expression of Erc1 7 0.65 1.18 0.15 5.00
89 INT245854 Gene_expression of Epc1 2 0.06 1.15 0.12 5.00
90 INT182469 Positive_regulation of Gene_expression of Cd34 6 0.43 1.27 0.12 5.00
91 INT245855 Binding of Erc1 2 0.06 0.54 0.09 5.00
92 INT229573 Positive_regulation of Positive_regulation of Kit 3 0.39 1.46 0.09 5.00
93 INT245858 Positive_regulation of Gene_expression of Eng 1 0.12 0 0.03 5.00
94 INT245862 Positive_regulation of Pou5f1 1 0.04 0 0 5.00
95 INT245853 Positive_regulation of Erc1 2 0.07 0.2 0 5.00
96 INT245857 Localization of Erc1 2 0.10 0.52 0 5.00
97 INT245864 Positive_regulation of Positive_regulation of Pou5f1 1 0.04 0 0 5.00
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