D:Thyroiditis

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pChart

Disease Term
Synonyms AUTOIMMUNE THYROIDITIS, Chronic Lymphocytic Thyroiditis, De Quervain S Thyroiditis, DE QUERVAINS THYROIDITIS, Giant Cell Thyroiditis, Granulomatous Thyroiditis, Hashimoto S Thyroiditis, Hashiomoto S Struma, Inflammation Of The Thyroid, SILENT LYMPHOCYTIC THYROIDITIS, Subacute Thyroiditis
Documents 421
Hot Single Events 123
Hot Interactions 4

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Thyroiditis. They are ordered first by their relevance to Thyroiditis and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT142845 Binding of HLA-B and SAT1 1 0.35 0.61 0.12 99.78
2 INT227760 Binding of HLA-A and HLA-B 1 0.20 3.35 0.3 99.76
3 INT70698 Binding of FANCB and FCGR3A 1 0.14 0.18 0.09 85.44
4 INT286228 Binding of Tpo and Ceat1 1 0.00 1.28 0.04 84.72
5 INT299787 Binding of IL2 and ISG20 1 0.04 0.82 0.21 75.84
6 INT249665 Binding of GOPC and PSS 1 0.02 3.13 0.21 74.24
7 INT311432 Binding of TSHR and TAOK1 1 0.12 1.05 0.07 70.00
8 INT259937 Binding of CSK and PTPN22 1 0.21 1.69 0.25 58.96
9 INT259939 Negative_regulation of Binding of CSK and PTPN22 1 0.19 0.62 0.03 58.96
10 INT259935 CSK Positive_regulation of Negative_regulation of LCK 1 0.09 0.57 0.03 52.40
11 INT259940 CSK Positive_regulation of Phosphorylation of LCK 1 0.09 0.51 0.03 49.20
12 INT307054 RHCE Regulation of AKTIP 1 0.00 0.6 0 39.12
13 INT191816 Binding of ETFA and TGM2 1 0.01 0.66 0 22.84
14 INT149117 Binding of CD80 and CTLA4 31 0.52 12.7 7.73 5.00
15 INT155484 Binding of CD86 and CTLA4 15 0.52 8.85 6.09 5.00
16 INT194647 Binding of CD28 and CD80 15 0.40 4.9 3.22 5.00
17 INT186126 Binding of CD28 and CTLA4 9 0.52 4.13 3.12 5.00
18 INT206764 Binding of AQP4 and Nqo1 8 0.05 13.45 2.84 5.00
19 INT186128 Binding of CD2 and CD58 8 0.10 7.59 2.76 5.00
20 INT29446 Crh Positive_regulation of Localization of POMC 8 0.38 1.87 2.58 5.00
21 INT194646 Binding of CD28 and CD86 7 0.40 2.69 2.21 5.00
22 INT59547 Avp Positive_regulation of Crh 2 0.14 1.13 1.47 5.00
23 INT189299 Atp6v1e1 Positive_regulation of Htr2a 1 0.01 1.01 1.41 5.00
24 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16 5.00
25 INT186125 Negative_regulation of Binding of CD2 and CD58 3 0.12 3.04 1.06 5.00
26 INT175805 Crh Positive_regulation of Gene_expression of POMC 1 0.12 1.07 0.99 5.00
27 INT91813 Binding of FAS and FASLG 4 0.23 9.89 0.99 5.00
28 INT334153 Binding of AQP4 and CSF2 1 0.16 3 0.75 5.00
29 INT189303 Atp6v1e1 Positive_regulation of Gene_expression of TPH1 1 0.01 0.16 0.73 5.00
30 INT172097 Binding of HLA-E and Trav6-3 10 0.02 3.71 0.71 5.00
31 INT153289 Binding of Lpar1 and Gpr87 2 0.29 1.19 0.67 5.00
32 INT220148 Binding of IGF1 and IGFBP3 12 0.36 5.56 0.66 5.00
33 INT299793 Positive_regulation of Binding of CD86 and CTLA4 1 0.17 1.64 0.63 5.00
34 INT299792 Positive_regulation of Binding of CD80 and CTLA4 1 0.17 1.63 0.63 5.00
35 INT345180 Binding of Lpar4 and Gpr87 1 0.06 0.69 0.59 5.00
36 INT345192 Binding of Gpr87 and Lpar5 1 0.07 0.69 0.59 5.00
37 INT112025 Binding of Hand1 and Il10 2 0.15 0.56 0.55 5.00
38 INT355881 Il17a Regulation of Gene_expression of Hand1 1 0.18 1.51 0.54 5.00
39 INT355878 Il17a Regulation of Eae1 1 0.06 1.52 0.54 5.00
40 INT355880 Il17a Regulation of Abi3 1 0.00 1.52 0.54 5.00
41 INT299785 CTLA4 Negative_regulation of Binding of CD28 2 0.17 1.8 0.5 5.00
42 INT158400 Binding of CD80 and CD86 3 0.36 0.76 0.48 5.00
43 INT175788 Il2 Positive_regulation of Localization of Avp 1 0.03 0.41 0.46 5.00
44 INT307781 Apoa1 Positive_regulation of LCAT 1 0.76 1.19 0.45 5.00
45 INT175802 Il1 Positive_regulation of Gene_expression of Fos 1 0.00 0.66 0.44 5.00
46 INT307780 Apoa1 Positive_regulation of Soat1 1 0.04 1.14 0.42 5.00
47 INT299789 IL4 Negative_regulation of Gene_expression of RAE1 1 0.00 0.84 0.41 5.00
48 INT299786 IL4 Negative_regulation of Gene_expression of CD5 1 0.07 0.82 0.4 5.00
49 INT189300 Atp6v1e1 Regulation of Gene_expression of Prl 1 0.03 0.29 0.39 5.00
50 INT299790 IL4 Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
51 INT299788 INCENP Negative_regulation of Gene_expression of NPEPPS 1 0.00 0.86 0.37 5.00
52 INT204943 Il6 Regulation of Slc39a14 1 0.00 0.54 0.36 5.00
53 INT153288 Binding of Lpar1 and Lpar6 2 0.31 0.78 0.36 5.00
54 INT354886 Thbs1 Regulation of Positive_regulation of Tgfb1 1 0.17 2.18 0.34 5.00
55 INT299791 Negative_regulation of Binding of CD28 and CTLA4 1 0.18 0.77 0.32 5.00
56 INT259936 CTLA4 Regulation of PTPN22 1 0.45 1.64 0.28 5.00
57 INT287794 Binding of IGHG3 and AIP 1 0.05 2.8 0.24 5.00
58 INT311872 IGHE Positive_regulation of Localization of Mmp9 1 0.01 1.35 0.22 5.00
59 INT355877 Binding of Hand1 and Il4 1 0.14 0.25 0.22 5.00
60 INT345196 Lpar2 Positive_regulation of Gene_expression of VEGFA 1 0.08 2.14 0.2 5.00
61 INT345186 Lpar2 Positive_regulation of Gene_expression of Plau 1 0.05 2.2 0.2 5.00
62 INT345172 Lpar1 Positive_regulation of S1pr1 1 0.21 0.19 0.19 5.00
63 INT322733 CD40LG Positive_regulation of Gene_expression of CD40 1 0.08 0.62 0.18 5.00
64 INT322734 Binding of CD40LG and Positive_regulation of CD40 1 0.07 0.62 0.18 5.00
65 INT193695 Il2 Positive_regulation of Ctla4 1 0.01 1.63 0.18 5.00
66 INT355882 TNF Positive_regulation of Gene_expression of Il12b 1 0.03 0.21 0.18 5.00
67 INT345176 Lpar1 Positive_regulation of Gene_expression of Car2 1 0.03 0.11 0.16 5.00
68 INT345157 Lpar1 Positive_regulation of Gene_expression of Gtf3a 1 0.00 0.89 0.15 5.00
69 INT198307 IL10 Positive_regulation of Gene_expression of IGHG3 2 0.01 1.21 0.15 5.00
70 INT345175 Lpar1 Regulation of Gpbar1 1 0.05 0.22 0.15 5.00
71 INT73076 IGF1 Positive_regulation of GH1 4 0.45 0.99 0.15 5.00
72 INT319119 SERPINE1 Negative_regulation of Positive_regulation of PLG 1 0.11 1.56 0.15 5.00
73 INT345171 Binding of Trip6 and Magi3 1 0.03 1.65 0.14 5.00
74 INT345146 Binding of Trip6 and Siva1 1 0.02 1.6 0.14 5.00
75 INT193693 Binding of Myd88 and Pain1 1 0.14 0.82 0.13 5.00
76 INT345165 Lpar5 Negative_regulation of Dmbx1 1 0.05 1.24 0.13 5.00
77 INT354888 Amy1 Regulation of Il10 1 0.02 1.41 0.13 5.00
78 INT354885 Amy1 Regulation of Gene_expression of Il10 1 0.03 1.41 0.13 5.00
79 INT345191 Lpar4 Negative_regulation of Dmbx1 1 0.04 1.25 0.13 5.00
80 INT193697 Apaf1 Positive_regulation of CASP9 1 0.02 1.84 0.12 5.00
81 INT345159 Binding of Cpa1 and Dmbx1 1 0.01 0 0.12 5.00
82 INT311871 Cav1 Regulation of Mch 1 0.01 0.24 0.11 5.00
83 INT189301 Atp6v1e1 Positive_regulation of Positive_regulation of Htr2a 1 0.01 1.13 0.11 5.00
84 INT189298 Atp6v1e1 Positive_regulation of Positive_regulation of Htr1a 1 0.00 1.15 0.11 5.00
85 INT284552 Binding of Cd8a and Mthfd1 2 0.03 1.32 0.1 5.00
86 INT345194 Lpar1 Positive_regulation of Gene_expression of VEGFA 1 0.07 0.87 0.1 5.00
87 INT345193 VEGFA Regulation of Gene_expression of Dmbx1 1 0.01 0.82 0.09 5.00
88 INT345195 VEGFA Positive_regulation of Gene_expression of Dmbx1 1 0.01 0.82 0.09 5.00
89 INT337072 Binding of Fmr1 and Gusb 1 0.19 1.55 0.08 5.00
90 INT259938 Binding of CTLA4 and PTPN22 1 0.36 0.85 0.08 5.00
91 INT199031 Binding of ALB and F2 1 0.05 1.78 0.08 5.00
92 INT345169 Lpar1 Negative_regulation of Dmbx1 1 0.08 2.26 0.08 5.00
93 INT193691 Positive_regulation of Positive_regulation of Bcr 1 0.01 0.07 0.08 5.00
94 INT193692 IgG2a Positive_regulation of Bcr 1 0.02 0.07 0.08 5.00
95 INT193694 IgG2a Positive_regulation of Tlr9 1 0.05 0.07 0.08 5.00
96 INT232917 Binding of KRT8 and KRT19 2 0.16 1.04 0.08 5.00
97 INT345178 S1pr1 Positive_regulation of Lpar1 1 0.14 0.09 0.07 5.00
98 INT279767 Binding of IGHG3 and KRT19 1 0.01 0.84 0.07 5.00
99 INT355879 Binding of Sry and Eae1 1 0.05 1.34 0.07 5.00
100 INT301402 Enpp2 Positive_regulation of Lpar1 2 0.33 0.55 0.07 5.00
101 INT345160 S1pr1 Positive_regulation of P2ry10 1 0.11 0.09 0.07 5.00
102 INT345198 S1pr1 Positive_regulation of Binding of Lpar1 and P2ry10 1 0.08 0.09 0.07 5.00
103 INT345179 Binding of Lpar1 and Gpbar1 1 0.05 0.15 0.07 5.00
104 INT345164 Binding of Lpar1 and P2ry10 1 0.14 0.09 0.07 5.00
105 INT345173 Binding of Siva1 and Lpar2 1 0.05 0.75 0.06 5.00
106 INT345197 Gpr87 Regulation of Gpr87 Regulation of Trp53 1 0.00 0.42 0.05 5.00
107 INT176095 Binding of Apc and EC 1 0.04 0.51 0.05 5.00
108 INT345181 Gpr87 Regulation of Trp53 1 0.01 0.42 0.05 5.00
109 INT178574 IL2RA Positive_regulation of Gene_expression of Cd3e 1 0.04 0.16 0.05 5.00
110 INT279763 Binding of IGHG3 and KRT18 1 0.00 0.43 0.04 5.00
111 INT345190 Lpar1 Regulation of Localization of Il6 1 0.05 1.19 0.04 5.00
112 INT279764 Binding of IGHG3 and BTG3 1 0.00 0.3 0.04 5.00
113 INT279766 Binding of IGHG3 and TGM1 1 0.01 0.3 0.04 5.00
114 INT345170 Pla2g6 Positive_regulation of Gene_expression of Lpar1 1 0.07 0 0.04 5.00
115 INT345182 Binding of Lpar1 and Gsn 1 0.04 0 0.04 5.00
116 INT279765 Binding of IGHG3 and KRT8 1 0.01 0.42 0.04 5.00
117 INT319120 CRP Positive_regulation of Gene_expression of SERPINE1 1 0.70 0.54 0.04 5.00
118 INT279762 Binding of KRT18 and KRT19 1 0.01 0.43 0.04 5.00
119 INT345147 Binding of S1pr1 and Gpbar1 1 0.03 0.07 0.03 5.00
120 INT345167 Binding of S1pr1 and Lpar1 1 0.13 0.07 0.03 5.00
121 INT345187 Positive_regulation of Binding of Alb and Lpar1 1 0.04 0.92 0.03 5.00
122 INT311870 Positive_regulation of Binding of Cd8a and Mthfd1 1 0.00 0.32 0.03 5.00
123 INT345183 Binding of Lhx3 and Trip6 1 0.03 0.66 0.03 5.00
124 INT345155 Lpar1 Positive_regulation of Lpar3 1 0.23 0.07 0.03 5.00
125 INT345161 Lpar1 Positive_regulation of Lpar2 1 0.36 0.07 0.03 5.00
126 INT345188 Binding of Lhx3 and Lpar2 1 0.06 0.66 0.03 5.00
127 INT345156 Binding of Alb and Lpar1 1 0.04 0.92 0.03 5.00
128 INT354890 Binding of TNF and Tnfsf13b 1 0.01 2.05 0 5.00
129 INT186502 Binding of AMELX and HLA-A 1 0.00 0.71 0 5.00
130 INT193696 Binding of CD8A and Trav6-3 1 0.00 0.85 0 5.00
131 INT345163 Lpar1 Positive_regulation of Gtf3a 1 0.00 0.77 0 5.00
132 INT354887 Binding of Tnfsf13b and Gtf3a 1 0.01 2.05 0 5.00
133 INT345168 Binding of Lpar1 and Ppard 1 0.03 0.21 0 5.00
134 INT345149 Enpp2 Regulation of Gene_expression of Lpar1 1 0.01 0.41 0 5.00
135 INT301410 Binding of Lpar1 and Lpar2 2 0.20 0.65 0 5.00
136 INT345158 Lpar1 Positive_regulation of Gene_expression of Sele 1 0.02 0.21 0 5.00
137 INT286229 Psmb9 Regulation of Tpo 1 0.07 1.01 0 5.00
138 INT345162 Dmbx1 Regulation of Gene_expression of Lpar1 1 0.03 0.41 0 5.00
139 INT345174 Spib Regulation of P2ry10 1 0.05 0.26 0 5.00
140 INT249666 Binding of CD81 and GOPC 1 0.06 1.31 0 5.00
141 INT345152 Binding of Lpar1 and Siva1 1 0.03 0.66 0 5.00
142 INT345154 Lpar1 Positive_regulation of Phosphorylation of Gsn 1 0.05 0 0 5.00
143 INT249664 Binding of CD81 and CHCHD2 1 0.00 2.51 0 5.00
144 INT345148 Lpar1 Positive_regulation of Gene_expression of Vcam1 1 0.07 0.21 0 5.00
145 INT173905 Binding of CD69 and LRP2 1 0.14 0.32 0 5.00
146 INT345189 Dmbx1 Positive_regulation of Lpar1 1 0.06 0.23 0 5.00
147 INT345150 Lpar1 Regulation of Gene_expression of Cd1 1 0.11 0.15 0 5.00
148 INT176096 Regulation of Binding of Angpt1 and Tek 1 0.07 0.54 0 5.00
149 INT345153 Dmbx1 Regulation of Enpp2 1 0.00 0.41 0 5.00
150 INT176097 Binding of Angpt1 and Tek 1 0.06 0.48 0 5.00
151 INT311816 CD79A Positive_regulation of RAB27A 1 0.01 0.47 0 5.00
152 INT345151 Binding of Trip6 and Lpar2 1 0.20 1.33 0 5.00
153 INT345177 Lpar1 Positive_regulation of Gpbar1 1 0.05 0 0 5.00
154 INT345184 Lpar1 Positive_regulation of Rock1 1 0.00 0.62 0 5.00
155 INT345185 Gtf3a Regulation of P2ry10 1 0.00 0.26 0 5.00
156 INT354889 Binding of TNF and Gtf3a 1 0.00 2.05 0 5.00
157 INT301409 Binding of Lpar6 and Gpr87 2 0.09 0 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Thyroiditis. They are ordered first by their pain relevance and then by number of times they were reported in Thyroiditis. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT18009 Positive_regulation of CRP 518 0.70 553.03 103.74 100.00
2 INT23257 Regulation of CRP 127 0.62 100.05 21.87 100.00
3 INT1878 Binding of HLA-B 440 0.48 321.16 127.36 100.00
4 INT130176 Positive_regulation of Gene_expression of CRP 125 0.66 137.06 25.9 100.00
5 INT99720 Positive_regulation of SAT1 21 0.69 26.55 1.56 100.00
6 INT195450 Binding of SAT1 3 0.37 4.11 0.39 100.00
7 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 100.00
8 INT137767 Gene_expression of Eae1 74 0.34 89.32 20.48 100.00
9 INT208225 Positive_regulation of Gene_expression of TSHR 2 0.46 2.84 0.22 100.00
10 INT311447 Negative_regulation of Gene_expression of TSHR 1 0.39 2.24 0.08 100.00
11 INT5871 Binding of IFNA2 38 0.48 20.35 6.46 99.92
12 INT285 Positive_regulation of Salpa1 73 0.68 61.47 9.19 99.90
13 INT17612 Gene_expression of CRP 676 0.78 580.61 119.03 99.84
14 INT45725 Binding of Pdia3 8 0.47 3.61 4.42 99.76
15 INT9082 Positive_regulation of ESR1 238 0.69 148.51 36.69 99.70
16 INT10194 Positive_regulation of IL6 702 0.70 600.62 183.38 99.70
17 INT33517 Gene_expression of TSHR 20 0.71 14.65 1.45 99.62
18 INT155 Positive_regulation of Prl 1233 0.70 317.93 457.82 99.52
19 INT204124 Transcription of CRP 14 0.69 20.79 2.71 99.44
20 INT284 Positive_regulation of Ggt6 18 0.67 13.56 4.62 99.44
21 INT9408 Positive_regulation of Crp 296 0.69 242.27 57.35 99.40
22 INT231573 Binding of PTPN22 5 0.44 7.94 2.33 99.40
23 INT4216 Gene_expression of CD40LG 328 0.78 256.02 44.23 99.36
24 INT9238 Gene_expression of IL6 1575 0.78 1135.66 424.22 99.28
25 INT11051 Positive_regulation of Gene_expression of IL6 415 0.69 319.21 109.3 99.28
26 INT125578 Positive_regulation of Localization of IGF1 6 0.60 7.59 0.53 99.18
27 INT307056 Positive_regulation of Localization of IGFBP3 1 0.39 0.99 0 99.18
28 INT34777 Localization of IGF1 82 0.80 42.68 8.62 98.94
29 INT36952 Negative_regulation of Tg 3 0.43 1.9 0.34 98.84
30 INT49370 Localization of IGFBP3 21 0.81 9.85 0.71 98.74
31 INT100861 Binding of CRP 179 0.48 175.2 26.45 98.64
32 INT97308 Gene_expression of TPO 15 0.65 13.26 2.12 98.60
33 INT27315 Positive_regulation of TPO 17 0.45 9.84 2.28 98.60
34 INT14026 Positive_regulation of Igh-6 24 0.68 10.84 4.32 98.60
35 INT49676 Positive_regulation of TG 10 0.48 9.09 0.44 98.32
36 INT4465 Gene_expression of CEL 116 0.77 98.35 23.58 98.28
37 INT39463 Positive_regulation of Tg 15 0.69 11.49 2.46 98.12
38 INT39462 Positive_regulation of Gene_expression of Tg 4 0.44 3.31 0.71 98.12
39 INT205796 Transcription of ERVW-1 5 0.52 2.16 0.24 97.88
40 INT28151 Positive_regulation of CTs 55 0.61 35.09 20.14 97.88
41 INT15654 Gene_expression of Tg 22 0.66 12.2 2.36 97.84
42 INT15516 Gene_expression of Crp 711 0.77 615.33 173.09 97.80
43 INT311452 Gene_expression of CASQ1 1 0.74 7.58 0.14 97.64
44 INT311450 Regulation of Gene_expression of TSHR 1 0.25 1.16 0.06 97.56
45 INT311439 Positive_regulation of Gene_expression of TAOK1 1 0.15 1.48 0.18 97.20
46 INT137178 Gene_expression of TLR3 46 0.72 24.97 4.33 97.18
47 INT186807 Positive_regulation of Gene_expression of TLR3 8 0.53 7.19 1.08 97.18
48 INT311448 Gene_expression of TAOK1 1 0.21 2.47 0.31 96.76
49 INT311438 Gene_expression of COL13A1 1 0.24 6.56 0.17 96.58
50 INT15804 Gene_expression of ISG20 83 0.75 44.33 10.58 96.56
51 INT13556 Gene_expression of CD4 367 0.78 230.82 41.74 96.56
52 INT122653 Positive_regulation of Gene_expression of CD4 48 0.68 22.5 5.96 96.56
53 INT15802 Positive_regulation of Gene_expression of ISG20 16 0.42 8.16 4.03 96.56
54 INT10721 Gene_expression of BDNF-AS 119 0.76 72.8 16.29 96.48
55 INT4210 Gene_expression of MB 24 0.78 11.74 2.32 96.08
56 INT96186 Gene_expression of MLF1IP 5 0.53 8.54 0.41 95.76
57 INT121801 Binding of Aip 18 0.36 24.1 5.26 95.76
58 INT602 Positive_regulation of TAS1R3 2 0.25 0.5 0.52 95.72
59 INT4435 Gene_expression of PIK3C2A 20 0.77 14.43 2.48 95.64
60 INT279202 Positive_regulation of Localization of CRP 3 0.69 2.45 0.72 95.20
61 INT106745 Localization of CRP 65 0.81 66.44 15.21 95.20
62 INT19330 Binding of HLA-A 99 0.48 76.26 22.85 95.08
63 INT8793 Gene_expression of H2 58 0.75 26.36 7.07 94.40
64 INT11379 Positive_regulation of Negative_regulation of IL1B 9 0.49 7.2 2.64 94.00
65 INT64959 Positive_regulation of Negative_regulation of IL6 5 0.42 5.16 1.86 94.00
66 INT5868 Positive_regulation of GNRH1 122 0.69 20.96 32.8 94.00
67 INT307060 Negative_regulation of AKTIP 6 0.01 2.79 0.08 93.92
68 INT26311 Negative_regulation of ACE2 8 0.59 16.35 1.94 93.84
69 INT16364 Gene_expression of HLA-DRA 234 0.78 118.81 45.01 93.64
70 INT240278 Localization of IGFALS 11 0.53 9.44 0.29 93.64
71 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 93.32
72 INT264170 Binding of BIRC2 1 0.01 1.19 0.08 93.32
73 INT86834 Positive_regulation of Tg 10 0.69 4.9 1.04 93.28
74 INT13520 Binding of HLA-DRB4 30 0.42 32.65 6.74 93.28
75 INT84546 Positive_regulation of Ppara 481 0.70 334.21 83.45 93.28
76 INT11380 Negative_regulation of IL1B 215 0.59 125.62 72.35 93.12
77 INT48901 Negative_regulation of IL6 186 0.57 136.33 57.87 93.12
78 INT14701 Negative_regulation of IFNA1 118 0.54 84.19 20.08 92.56
79 INT49130 Positive_regulation of IGFBP3 49 0.63 27.55 4.78 92.44
80 INT219392 Positive_regulation of SLC5A8 1 0.41 2.4 0.23 92.12
81 INT23572 Binding of BW22 2 0.36 1.64 0.25 91.76
82 INT132477 Negative_regulation of TSHB 5 0.45 3.24 0.05 91.60
83 INT2120 Gene_expression of CD79A 159 0.78 111.69 17.16 91.52
84 INT6483 Gene_expression of TNF 3152 0.78 2515.62 929.82 91.44
85 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 91.44
86 INT189293 Positive_regulation of Gene_expression of MHC class II protein 1 0.14 1.05 0.23 91.20
87 INT10359 Gene_expression of Ifng 159 0.78 79.6 72.14 90.92
88 INT189283 Gene_expression of MHC II protein 1 0.23 1.63 0.39 90.80
89 INT42980 Gene_expression of GAD1 139 0.69 94.77 45.11 90.76
90 INT17551 Positive_regulation of Gene_expression of HLA-DRA 31 0.70 15.39 6 90.60
91 INT739 Negative_regulation of POMC 358 0.59 102.28 166.77 90.24
92 INT16960 Gene_expression of Crp 166 0.76 116.21 34.07 90.24
93 INT142404 Gene_expression of THPO 18 0.77 4.39 0.56 90.24
94 INT9682 Positive_regulation of IGF1 238 0.70 120.03 26.36 89.84
95 INT101896 Binding of SFPQ 1 0.29 1.72 0.11 89.64
96 INT335653 Positive_regulation of Tg(EGFR)4Jlj 1 0.07 0.24 0 88.48
97 INT101895 Binding of SLC17A5 5 0.36 7.08 0.18 88.16
98 INT154706 Gene_expression of Tg 9 0.38 4.95 0.64 87.76
99 INT18981 Gene_expression of ABAT 78 0.68 38.35 61.36 87.44
100 INT2890 Positive_regulation of MB 39 0.70 29.58 6.01 87.40
101 INT711 Positive_regulation of PIK3C2A 83 0.70 76.87 13.18 87.40
102 INT189088 Gene_expression of Psmb9 2 0.75 18.79 0.75 86.48
103 INT286197 Positive_regulation of Gene_expression of Psmb9 1 0.49 2.44 0.21 86.48
104 INT286198 Negative_regulation of Psmb9 1 0.42 2.95 0.03 86.48
105 INT467 Gene_expression of POMC 1048 0.78 332.8 394.16 86.32
106 INT89933 Negative_regulation of Tg 2 0.04 1.78 0.06 86.20
107 INT61628 Negative_regulation of Gene_expression of IL4 31 0.55 20.96 8.18 85.92
108 INT921 Regulation of GH1 172 0.60 52.88 51.04 85.60
109 INT11729 Regulation of IGF1 71 0.61 44.58 9.71 85.48
110 INT48269 Negative_regulation of FANCB 16 0.56 5.34 1.38 85.44
111 INT749 Gene_expression of HLA-B 341 0.75 224.12 77.37 85.36
112 INT56298 Gene_expression of IL4 306 0.78 182.18 72.92 85.04
113 INT3375 Gene_expression of IGHE 535 0.77 387.47 65.46 85.04
114 INT311455 Negative_regulation of Gene_expression of COL13A1 1 0.13 2 0.04 84.84
115 INT311451 Negative_regulation of COL13A1 1 0.13 1.3 0 84.84
116 INT7205 Positive_regulation of HBG1 65 0.69 40.35 6.37 84.48
117 INT118343 Positive_regulation of Eae1 121 0.39 136.06 34.87 83.76
118 INT28291 Gene_expression of Tshr 3 0.11 1.5 0.65 83.16
119 INT25271 Positive_regulation of MTG1 21 0.67 13.59 5.96 81.92
120 INT3564 Positive_regulation of Aip 11 0.58 15.38 3.62 81.92
121 INT186804 Binding of TLR3 14 0.45 8.41 0.79 81.44
122 INT148207 Gene_expression of CTLA4 53 0.77 29.13 12.07 81.16
123 INT2216 Gene_expression of SELL 92 0.77 59.29 17.71 81.16
124 INT173910 Gene_expression of LRP2 24 0.75 19.99 4.09 79.84
125 INT173914 Regulation of Gene_expression of LRP2 3 0.60 6.49 0.78 79.84
126 INT89308 Positive_regulation of Binding of IFNA1 12 0.49 10.64 2.04 79.64
127 INT207289 Gene_expression of G0S2 5 0.59 2 0.07 79.44
128 INT6302 Binding of IFNA1 196 0.48 133.85 32.73 79.20
129 INT3286 Positive_regulation of Gpt 90 0.69 45.08 28.34 79.04
130 INT27551 Gene_expression of SERPINH1 45 0.62 42.87 9.04 78.92
131 INT4612 Positive_regulation of Localization of CGA 64 0.64 8.51 22.39 78.60
132 INT15515 Positive_regulation of Crp 700 0.70 604.24 150.15 78.48
133 INT1437 Negative_regulation of Pomc 132 0.59 35.22 60.97 78.28
134 INT1793 Localization of CGA 379 0.81 67.38 114.69 78.20
135 INT1898 Regulation of Crh 220 0.62 61.33 102.64 77.72
136 INT157 Positive_regulation of Localization of Prl 790 0.70 104.54 374.78 76.36
137 INT158 Localization of Prl 2431 0.81 378.96 952.2 75.96
138 INT18672 Gene_expression of Ncam1 54 0.78 36.64 18.79 75.00
139 INT38871 Binding of TFPI 12 0.32 5.9 2.36 75.00
140 INT6105 Positive_regulation of IL2 133 0.69 82.76 34.67 75.00
141 INT531 Gene_expression of GH1 376 0.75 193.45 46.24 75.00
142 INT7538 Negative_regulation of IL2 95 0.57 47.31 31.7 75.00
143 INT14149 Binding of C6orf25 11 0.48 9.04 1.71 75.00
144 INT16385 Regulation of C3 20 0.41 9.98 1.92 74.76
145 INT23621 Regulation of C4A 10 0.44 5.07 0.84 74.76
146 INT125725 Regulation of C1QC 1 0.06 0.83 0.18 74.76
147 INT46383 Negative_regulation of TRGC1 42 0.55 44.03 6.2 74.36
148 INT70701 Binding of FCGR3A 5 0.36 1.2 0.38 74.32
149 INT17401 Gene_expression of IGF1 475 0.78 232.18 62.07 74.08
150 INT28950 Positive_regulation of Gene_expression of IGF1 99 0.69 46.9 16.47 74.08
151 INT68244 Positive_regulation of Ighg1 60 0.61 48.86 5.01 74.00
152 INT573 Negative_regulation of C3 60 0.59 41.37 7.78 73.88
153 INT23620 Negative_regulation of C4A 24 0.57 15.1 2.23 73.88
154 INT125724 Negative_regulation of C1QC 1 0.10 0.82 0.18 73.88
155 INT62496 Binding of CSF1 6 0.36 4.55 1.14 72.88
156 INT80024 Negative_regulation of KLRD1 3 0.04 0.91 0.88 71.76
157 INT8518 Localization of Ifng 53 0.81 36.68 24.13 71.52
158 INT322739 Localization of TAOK1 1 0.02 1.24 0 71.08
159 INT63975 Positive_regulation of Il10 175 0.68 134.13 54.69 70.88
160 INT5058 Positive_regulation of IFNA1 356 0.70 245.75 60.52 70.88
161 INT13186 Positive_regulation of Il4 113 0.68 71.22 31.4 70.88
162 INT11803 Positive_regulation of Il2 62 0.70 31.44 18.93 70.88
163 INT100938 Positive_regulation of Il13 47 0.69 42.11 14.36 70.88
164 INT97439 Positive_regulation of Il5 46 0.60 25.6 9.47 70.88
165 INT311440 Binding of G0S2 1 0.00 0.55 0 70.48
166 INT9660 Regulation of TNF 363 0.62 312.94 139.99 70.16
167 INT9210 Regulation of IL6 166 0.62 125.61 49.95 70.16
168 INT25517 Regulation of NFKB1 41 0.61 22.28 16.09 70.16
169 INT15803 Regulation of IFNG 21 0.44 12.57 5.98 70.16
170 INT105378 Regulation of IL12A 6 0.26 8.82 2.15 70.16
171 INT60291 Regulation of SOAT1 9 0.19 3.99 1.17 70.16
172 INT70667 Regulation of JUND 3 0.33 2.36 1.05 70.16
173 INT10709 Negative_regulation of CD4 106 0.59 95.6 14.89 70.00
174 INT204183 Negative_regulation of Negative_regulation of CD4 3 0.30 1.79 0.22 70.00
175 INT3403 Positive_regulation of BCAR1 18 0.63 18.95 3.23 69.36
176 INT43907 Binding of CD79A 28 0.48 28.11 3.04 69.36
177 INT4004 Gene_expression of IGHG3 321 0.71 221.03 42.33 69.20
178 INT1125 Positive_regulation of IGHG3 130 0.69 112.07 13.18 69.04
179 INT54763 Binding of Il6 82 0.48 63.27 12.89 69.04
180 INT24978 Binding of SFTPA1 22 0.47 15.09 7.76 68.96
181 INT94467 Positive_regulation of Hand1 71 0.58 59 16.96 68.92
182 INT84732 Positive_regulation of Hand2 81 0.69 62.07 22 68.92
183 INT194846 Positive_regulation of Positive_regulation of Il10 9 0.57 5.07 3.71 68.92
184 INT62497 Binding of Il4 7 0.26 4.19 3.88 68.56
185 INT51646 Binding of IL3 3 0.37 3.26 0.56 68.08
186 INT101013 Regulation of HLA-A 7 0.33 6.7 1.8 67.32
187 INT335651 Positive_regulation of Gene_expression of Tg(EGFR)4Jlj 1 0.07 1.01 0 67.12
188 INT211806 Gene_expression of PLXNC1 4 0.63 2.95 0.07 67.04
189 INT335650 Gene_expression of Tg(EGFR)4Jlj 1 0.09 0.49 0 66.68
190 INT48141 Binding of Csf3 18 0.39 9.93 1.71 65.92
191 INT1781 Negative_regulation of Gh1 127 0.59 16.94 51.77 65.76
192 INT1376 Binding of Trh 121 0.48 20 69.86 65.72
193 INT166140 Binding of Rrad 2 0.12 3.54 0.6 65.36
194 INT34869 Negative_regulation of PTGS2 778 0.59 366.76 319.85 65.28
195 INT256822 Binding of Gm3813 2 0.36 1.81 0.08 64.72
196 INT5788 Gene_expression of IL2RA 60 0.75 40.67 9.98 64.32
197 INT5653 Positive_regulation of ELANE 136 0.70 72.78 27.94 64.16
198 INT403 Localization of Trh 241 0.81 28.55 81.45 63.52
199 INT9223 Localization of Ighg1 22 0.78 11.03 3.67 63.28
200 INT26545 Gene_expression of Hras1 173 0.78 79.54 13.21 63.12
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