D:Uterine Prolapse

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pChart

Disease Term
Synonyms Descens Uteri, Descensus Uteri, Prolapse Of Uterus, Prolapse Uterine, Prolapse Vaginal, Prolapses Uterine, Prolapses Vaginal, Uterine Hernia, Uterine Hernias, Uterine Prolapses, VAGINAL PROLAPSE
Documents 124
Hot Single Events 6
Hot Interactions 0

Molecular Interactions

The table below shows the top 200 pain related interactions that have been reported for Uterine Prolapse. They are ordered first by their relevance to Uterine Prolapse and then by their general relevance to pain. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT291556 Binding of ESR1 and Sec22b 2 0.00 0.86 0.5 5.00
2 INT260267 Binding of TFAM and TP53 2 0.37 2.1 0.03 5.00
3 INT201800 OLFM1 Regulation of EHF 1 0.05 0 0 5.00
4 INT287088 Binding of EEC1 and Vamp3 1 0.09 1.02 0 5.00
5 INT201799 PGR Regulation of HSD17B2 1 0.12 0.08 0 5.00

Single Events

The table below shows the top 200 pain related interactions that have been reported for Uterine Prolapse. They are ordered first by their pain relevance and then by number of times they were reported in Uterine Prolapse. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Overall Pain Relevance Term Relevance
1 INT57064 Positive_regulation of APC 72 0.66 48.5 5.08 99.98
2 INT253294 Positive_regulation of Oca2 5 0.11 1.62 0.13 93.20
3 INT52732 Negative_regulation of CRP 169 0.59 138.47 40.33 89.92
4 INT5164 Negative_regulation of Ldlr 83 0.58 55.01 7.87 89.92
5 INT3361 Positive_regulation of Esr1 273 0.69 208.53 44.81 85.04
6 INT106807 Binding of Lama5 2 0.08 1.71 0.24 80.24
7 INT123016 Gene_expression of Sec22b 11 0.41 5.1 2.5 66.80
8 INT20462 Binding of ESR1 210 0.44 102.7 26.34 61.80
9 INT168446 Gene_expression of Prep 25 0.64 15.17 5.94 50.00
10 INT227524 Positive_regulation of Gene_expression of Prep 13 0.48 7.69 3.28 50.00
11 INT178962 Gene_expression of Oca2 15 0.19 5.15 0.38 50.00
12 INT252951 Localization of Oca2 2 0.17 1.53 0.23 50.00
13 INT306141 Binding of Oca2 1 0.10 0.17 0 50.00
14 INT292304 Gene_expression of PLXNB1 1 0.69 0.26 0.1 49.60
15 INT287087 Localization of EEC1 2 0.61 1.6 0.72 34.08
16 INT200806 Binding of EEC1 6 0.39 4.24 0.29 31.36
17 INT2848 Localization of ABCA1 23 0.70 10.64 4.73 31.28
18 INT287082 Gene_expression of Vamp3 1 0.18 0.99 0.11 27.28
19 INT47543 Positive_regulation of Chrm3 11 0.38 5.23 2.17 19.44
20 INT204343 Positive_regulation of Gene_expression of TFAM 7 0.50 3.87 0 19.36
21 INT130705 Gene_expression of TFAM 50 0.77 38.85 2.79 19.00
22 INT28361 Gene_expression of TP53 443 0.78 384.86 28.8 16.76
23 INT185825 Localization of MMP7 10 0.78 2.85 1.11 13.68
24 INT10832 Gene_expression of IL8 1050 0.78 698.72 270 5.00
25 INT5972 Gene_expression of IL1B 948 0.78 510.91 263.97 5.00
26 INT55879 Gene_expression of CCL2 421 0.78 240.74 166.02 5.00
27 INT120811 Gene_expression of Gopc 1174 0.59 428.49 150.55 5.00
28 INT1047 Negative_regulation of LH 314 0.59 53.71 135.89 5.00
29 INT90091 Gene_expression of GOPC 967 0.67 366.22 103.6 5.00
30 INT822 Gene_expression of ESR1 529 0.78 302.16 63.64 5.00
31 INT2056 Negative_regulation of Gnrh1 175 0.59 33.43 63.32 5.00
32 INT109910 Gene_expression of CCL16 104 0.74 76.1 43.97 5.00
33 INT5973 Regulation of IL1B 109 0.62 66.6 39.88 5.00
34 INT4727 Regulation of TAC1 60 0.47 6.74 32.83 5.00
35 INT3330 Gene_expression of AGT 149 0.76 98.65 22.73 5.00
36 INT14731 Positive_regulation of TGFB1 78 0.67 52.57 22.23 5.00
37 INT10833 Regulation of Gene_expression of IL8 68 0.62 38.74 18.46 5.00
38 INT55878 Regulation of Gene_expression of CCL2 34 0.62 15.71 17.97 5.00
39 INT65856 Positive_regulation of TP53 138 0.67 112.65 16.71 5.00
40 INT170855 Negative_regulation of GOPC 188 0.38 70.92 15.41 5.00
41 INT16167 Negative_regulation of DMD 186 0.57 108.71 15.25 5.00
42 INT73916 Gene_expression of Esr1 58 0.77 26.59 15.15 5.00
43 INT16166 Positive_regulation of DMD 348 0.67 133.22 15.06 5.00
44 INT79545 Positive_regulation of Gene_expression of ESR1 82 0.64 39.42 12.18 5.00
45 INT32203 Negative_regulation of Crp 48 0.58 32.77 11.89 5.00
46 INT2160 Negative_regulation of Negative_regulation of LH 22 0.58 4.58 11.53 5.00
47 INT49802 Localization of MUC1 75 0.81 44.74 8.87 5.00
48 INT939 Gene_expression of PAEP 86 0.77 31.02 8.59 5.00
49 INT61363 Positive_regulation of TFAM 43 0.69 26.43 8.14 5.00
50 INT15687 Regulation of ESR1 91 0.60 40.42 7.95 5.00
51 INT11823 Positive_regulation of GGT1 53 0.67 45.84 7.55 5.00
52 INT57748 Positive_regulation of Gene_expression of TP53 85 0.69 79.55 7.49 5.00
53 INT25022 Binding of PAEP 66 0.42 22.83 6.59 5.00
54 INT13683 Regulation of Ugt1a6 9 0.28 2.5 6.33 5.00
55 INT10147 Gene_expression of Serpinc1 28 0.76 17.73 5.77 5.00
56 INT38556 Gene_expression of DBT 47 0.50 12.52 5.6 5.00
57 INT230829 Localization of Cyp2d4 3 0.63 0.61 5.18 5.00
58 INT12104 Positive_regulation of PLG 45 0.68 28.94 4.81 5.00
59 INT20461 Binding of Esr1 34 0.48 9.58 3.66 5.00
60 INT16165 Regulation of DMD 114 0.60 35.13 3.64 5.00
61 INT178631 Phosphorylation of ESR1 21 0.75 9.16 3.36 5.00
62 INT171998 Binding of DMD 58 0.47 38.13 3.35 5.00
63 INT19293 Protein_catabolism of FN1 7 0.95 5.15 2.97 5.00
64 INT8103 Binding of TP53 46 0.44 40.2 2.96 5.00
65 INT102233 Gene_expression of MMP7 40 0.76 15.78 2.93 5.00
66 INT101246 Gene_expression of Gata6 6 0.68 3.03 2.68 5.00
67 INT10070 Negative_regulation of Fshb 13 0.42 3.48 2.5 5.00
68 INT68781 Negative_regulation of TFAM 15 0.58 10.01 2.42 5.00
69 INT61340 Regulation of Prep 7 0.50 6.13 2.31 5.00
70 INT83236 Localization of PGR 14 0.73 8.26 2.23 5.00
71 INT32677 Positive_regulation of Npepo 8 0.49 3.1 1.92 5.00
72 INT192295 Protein_catabolism of MMP7 10 0.86 2.68 1.86 5.00
73 INT181720 Regulation of IL15 9 0.20 3.65 1.79 5.00
74 INT201810 Gene_expression of LEFTY2 6 0.56 3.94 1.74 5.00
75 INT159278 Negative_regulation of Ugt1a6 6 0.51 2.11 1.7 5.00
76 INT197889 Binding of Sec22b 7 0.04 4.38 1.46 5.00
77 INT34421 Negative_regulation of Npepo 3 0.27 1.28 1.43 5.00
78 INT227424 Binding of Prep 6 0.35 2.61 1.39 5.00
79 INT148221 Gene_expression of CXCL14 5 0.74 2.91 1.34 5.00
80 INT180580 Binding of HEYL 7 0.17 4.49 1.15 5.00
81 INT89105 Gene_expression of Gapdh 27 0.75 4.32 1.15 5.00
82 INT59768 Regulation of TFAM 7 0.45 4.64 1.08 5.00
83 INT22139 Negative_regulation of Phdlc1 7 0.25 5.19 1.06 5.00
84 INT103834 Regulation of RETNLB 4 0.04 3.87 1.02 5.00
85 INT138201 Transcription of PAEP 4 0.67 1.8 1.02 5.00
86 INT134822 Gene_expression of Gja1 18 0.72 4.2 1 5.00
87 INT139527 Positive_regulation of Gene_expression of PAEP 16 0.43 4.66 0.98 5.00
88 INT38557 Positive_regulation of Gene_expression of DBT 8 0.37 2.05 0.92 5.00
89 INT185837 Regulation of Gene_expression of MMP7 6 0.44 2.87 0.92 5.00
90 INT24410 Negative_regulation of Gene_expression of Serpinc1 4 0.28 1.98 0.91 5.00
91 INT38373 Positive_regulation of Ap3b1 4 0.37 1.01 0.86 5.00
92 INT11949 Negative_regulation of Apob 11 0.09 8.13 0.85 5.00
93 INT35141 Regulation of PLG 6 0.44 2.64 0.85 5.00
94 INT201853 Transcription of MMP7 4 0.67 1.63 0.78 5.00
95 INT102813 Regulation of Gene_expression of TP53 25 0.59 25.95 0.75 5.00
96 INT187071 Localization of ESRRB 2 0.04 0.9 0.67 5.00
97 INT113565 Regulation of PLAU 6 0.58 5.8 0.66 5.00
98 INT134599 Regulation of HSD17B2 2 0.44 1.28 0.63 5.00
99 INT161807 Phosphorylation of ROS1 10 0.43 4.86 0.62 5.00
100 INT122525 Regulation of FOXO1 3 0.58 1.76 0.44 5.00
101 INT201816 Gene_expression of EHF 2 0.45 0.63 0.37 5.00
102 INT173940 Positive_regulation of Negative_regulation of DMD 8 0.59 2.97 0.36 5.00
103 INT185839 Binding of MMP7 3 0.36 1.29 0.33 5.00
104 INT176586 Positive_regulation of Binding of ESR1 11 0.41 4.64 0.33 5.00
105 INT201803 Regulation of SIAE 1 0.03 0.58 0.3 5.00
106 INT201804 Gene_expression of ENO3 2 0.13 0.96 0.3 5.00
107 INT166958 Gene_expression of LYRM4 4 0.18 2.9 0.27 5.00
108 INT201808 Negative_regulation of Gene_expression of LEFTY2 2 0.31 0.55 0.24 5.00
109 INT180599 Gene_expression of EEC1 5 0.63 2.73 0.23 5.00
110 INT104906 Negative_regulation of Alpl 5 0.31 1.72 0.21 5.00
111 INT185836 Positive_regulation of Gene_expression of MMP7 4 0.43 0.41 0.2 5.00
112 INT201815 Localization of HRASLS 2 0.08 0.58 0.17 5.00
113 INT104905 Localization of Alpl 2 0.08 1.08 0.13 5.00
114 INT114110 Negative_regulation of EEC1 2 0.37 2.35 0.12 5.00
115 INT328557 Transcription of CD3E 1 0.55 0.73 0.11 5.00
116 INT305227 Negative_regulation of Gene_expression of Prep 2 0.11 1.42 0.1 5.00
117 INT320132 Positive_regulation of Binding of Sec22b 1 0.02 0.73 0.09 5.00
118 INT320131 Positive_regulation of Gene_expression of Sec22b 1 0.02 0.69 0.08 5.00
119 INT188252 Positive_regulation of DKK1 4 0.41 2.94 0.08 5.00
120 INT192687 Negative_regulation of PAX5 9 0.40 1.42 0.08 5.00
121 INT216691 Gene_expression of CASK 1 0.06 1.32 0.05 5.00
122 INT201817 Regulation of EHF 1 0.15 0.29 0.05 5.00
123 INT201818 Regulation of CDH2 3 0.09 1.89 0.04 5.00
124 INT287085 Negative_regulation of Myh9 1 0.21 0.6 0.03 5.00
125 INT132717 Localization of PAX5 3 0.50 1.27 0.03 5.00
126 INT292302 Localization of PLXNA1 1 0.36 0 0 5.00
127 INT287083 Binding of Vamp3 1 0.14 1.58 0 5.00
128 INT328555 Binding of UAE1 1 0.14 0.69 0 5.00
129 INT292306 Binding of PLXNB1 1 0.33 0 0 5.00
130 INT204345 Negative_regulation of Gene_expression of TFAM 3 0.42 1.48 0 5.00
131 INT201811 Negative_regulation of Gene_expression of CDH2 1 0.12 0.09 0 5.00
132 INT175651 Gene_expression of CDH2 5 0.36 2.59 0 5.00
133 INT201809 Regulation of SOX4 1 0.38 0.06 0 5.00
134 INT287084 Regulation of Vamp3 1 0.12 0.71 0 5.00
135 INT328556 Localization of UAE1 1 0.27 2.18 0 5.00
136 INT201802 Negative_regulation of Negative_regulation of OLFM1 1 0.10 0 0 5.00
137 INT305296 Regulation of Gene_expression of TFAM 1 0.45 2.68 0 5.00
138 INT292307 Regulation of PLXNB1 1 0.40 0 0 5.00
139 INT292303 Transcription of PLXNB1 1 0.61 0 0 5.00
140 INT201812 Localization of EHF 1 0.31 0.19 0 5.00
141 INT201801 Regulation of ENO3 1 0.12 0.21 0 5.00
142 INT201814 Negative_regulation of CDH2 4 0.20 0.25 0 5.00
143 INT201805 Negative_regulation of Negative_regulation of CDH2 1 0.09 0.25 0 5.00
144 INT201806 Localization of OLFM1 1 0.68 0.19 0 5.00
145 INT292305 Transcription of PEX19 1 0.52 0 0 5.00
146 INT201813 Negative_regulation of OLFM1 1 0.10 0 0 5.00
147 INT287086 Regulation of Gene_expression of EEC1 1 0.36 0.42 0 5.00
148 INT201807 Localization of HSD17B2 1 0.68 0.19 0 5.00
149 INT305295 Regulation of Binding of TP53 1 0.39 1.09 0 5.00
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