Evaluation:4

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These are evaluation pages designed to aid in the manual curation process.

These are ints 1500-2000 ordered by relevance to pain.

Molecular Interactions

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT132412 Negative_regulation of Ngf Negative_regulation of Ptgs1 1 0.01 0.81 1.31
2 INT198957 Binding of Cnr1 and Mastl 1 0.00 0 1.31
3 INT131886 Creb1 Positive_regulation of Gene_expression of Prkcg 1 0.03 0 1.31
4 INT131256 Positive_regulation of Nfkb1 Positive_regulation of Gene_expression of Nfkbia 1 0.38 0.94 1.31
5 INT121705 IL1B Positive_regulation of Gene_expression of MMP3 3 0.49 1.2 1.3
6 INT192080 Foxm1 Positive_regulation of Cnr1 2 0.14 0.72 1.3
7 INT242605 Gdnf Positive_regulation of Trpv1 1 0.26 0.17 1.3
8 INT341336 Binding of Pepd and Nav1 1 0.07 0.92 1.3
9 INT124925 Negative_regulation of Slc6a1 Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
10 INT96707 Ntf3 Positive_regulation of Localization of SST 1 0.01 0 1.3
11 INT299281 Binding of RPTOR and MAPKAP1 1 0.23 0.21 1.3
12 INT261841 Mastl Positive_regulation of Trpa1 1 0.00 0.82 1.3
13 INT281479 Drd2 Positive_regulation of Penk 1 0.23 0.4 1.3
14 INT96708 Bdnf Positive_regulation of Localization of SST 1 0.01 0 1.3
15 INT27425 Mtr Positive_regulation of Gene_expression of Il1f5 1 0.06 0 1.3
16 INT314211 Ngf Positive_regulation of Gene_expression of Agtrap 1 0.04 1.15 1.3
17 INT62448 Il2 Positive_regulation of Crh 1 0.59 0.36 1.3
18 INT330124 Positive_regulation of Bdkrb1 Positive_regulation of RT1-O2-ps 1 0.02 1.97 1.3
19 INT142207 Adcyap1 Positive_regulation of Localization of Gh 1 0.07 0 1.3
20 INT201942 DPP4 Negative_regulation of CXCL10 1 0.33 0.9 1.3
21 INT148778 Binding of Usf1 and Rtn1 1 0.40 0.85 1.3
22 INT168229 Oprm1 Regulation of Cea 1 0.10 0.26 1.3
23 INT169297 TRPV1 Positive_regulation of EGFR 1 0.64 0.37 1.3
24 INT49231 TAC1 Negative_regulation of Penk 1 0.00 0 1.3
25 INT95275 Binding of Edn1 and Ece1 1 0.32 2.09 1.3
26 INT95274 Regulation of Binding of Edn1 and Ece1 1 0.39 2.09 1.3
27 INT124926 Negative_regulation of Prkaca Negative_regulation of Localization of Pag1 1 0.00 0.61 1.3
28 INT57956 LOC365260 Negative_regulation of Cck 1 0.11 0 1.3
29 INT95457 Nka1 Positive_regulation of Tacr1 1 0.63 0.29 1.3
30 INT94367 Binding of ARRB1 and TP53INP2 1 0.25 0 1.3
31 INT186393 Binding of TNF and Tnfrsf1a 9 0.37 8.55 1.29
32 INT107858 PRSS1 Positive_regulation of F2RL1 6 0.12 4.23 1.29
33 INT242623 Binding of Ntf3 and Ntrk3 5 0.22 1.31 1.29
34 INT121096 Binding of Calca and Trpv1 3 0.37 1.23 1.29
35 INT95406 Trib3 Positive_regulation of Ephb1 2 0.08 0.96 1.29
36 INT158144 Binding of Gpx1 and Glyat 2 0.31 0 1.29
37 INT66428 Dcc Positive_regulation of Fos 2 0.05 0.39 1.29
38 INT208990 Binding of CALM1 and Trpv1 1 0.10 0.07 1.29
39 INT138211 Mzb1 Regulation of Sst 1 0.05 0.41 1.29
40 INT147653 TACR1 Positive_regulation of TRPV1 1 0.02 0.72 1.29
41 INT148775 Binding of Calca and Usf1 1 0.43 0.85 1.29
42 INT112097 Sstr1 Positive_regulation of Adarb1 1 0.02 0.15 1.29
43 INT138212 Mzb1 Regulation of Localization of Sst 1 0.12 0.41 1.29
44 INT89878 Pdyn Positive_regulation of Gene_expression of Nkx2-5 1 0.35 0 1.29
45 INT48881 TWIST1 Positive_regulation of Localization of Abat 1 0.02 0.44 1.29
46 INT262377 Binding of Comt and Fmod 1 0.06 1.47 1.29
47 INT139722 PROC Positive_regulation of CDCP1 1 0.00 1.61 1.29
48 INT57263 Binding of Oprd1 and Atxn2l 1 0.02 0 1.29
49 INT18659 Plat Regulation of ZC3H12D 1 0.02 0.1 1.29
50 INT138213 Mzb1 Regulation of Localization of Tac1 1 0.01 0.41 1.29
51 INT131184 PTGER2 Positive_regulation of Gene_expression of IGF1 1 0.63 2.47 1.29
52 INT85742 Pdyn Positive_regulation of Rbm39 1 0.01 0.17 1.29
53 INT194408 Regulation of Binding of CALCA and DCLK3 1 0.15 0 1.29
54 INT135830 Gch1 Regulation of Nos2 1 0.65 0 1.29
55 INT130333 FUT3 Negative_regulation of Positive_regulation of Tnf 1 0.01 0.36 1.29
56 INT276282 Binding of Atrn and Mc1r 1 0.32 0.41 1.29
57 INT121802 DEAF1 Negative_regulation of HTR1A 1 0.46 0.88 1.29
58 INT128310 Oprm1 Positive_regulation of Oprm1 1 0.00 0.1 1.29
59 INT57262 Binding of Gria4 and Oprd1 1 0.06 0 1.29
60 INT138210 Mzb1 Regulation of Calca 1 0.25 0.41 1.29
61 INT63407 Binding of Oprl1 and Pck1 1 0.40 0 1.29
62 INT89873 Pdyn Positive_regulation of Gene_expression of Gata4 1 0.23 0 1.29
63 INT24378 Penk Regulation of Oprl1 1 0.10 0 1.29
64 INT108386 IL1B Positive_regulation of MMP1 3 0.27 1.56 1.28
65 INT31008 Crh Positive_regulation of Pomc 3 0.49 2.31 1.28
66 INT86636 POMC Positive_regulation of Gene_expression of KRT16 2 0.39 0.83 1.28
67 INT31771 Penk Positive_regulation of Nppa 1 0.22 0.13 1.28
68 INT168866 Binding of RYR1 and Cd38 1 0.02 0.17 1.28
69 INT115985 Cpe Positive_regulation of Binding of Gnas 1 0.00 0.17 1.28
70 INT7284 Abat Regulation of Sst 1 0.18 0 1.28
71 INT89943 Binding of Oprm1 and Il2 1 0.03 0.53 1.28
72 INT114929 Positive_regulation of Binding of Oprm1 and Crebbp 1 0.06 0.14 1.28
73 INT154518 Binding of Ephb6 and Grin2b 1 0.21 0.24 1.28
74 INT136200 Binding of Penk and NUP37 1 0.04 0 1.28
75 INT89876 Pdyn Positive_regulation of Gata4 1 0.23 0 1.28
76 INT161995 Binding of Ctu2 and Fbxo23 1 0.06 0.33 1.28
77 INT83707 Acyp2-ps1 Regulation of Casp3 1 0.17 0 1.28
78 INT73597 Positive_regulation of BAX Positive_regulation of Casp1 1 0.06 0.69 1.28
79 INT48117 GH1 Positive_regulation of CGA 1 0.10 0 1.28
80 INT255380 Binding of AIS and Nav1 1 0.02 0 1.28
81 INT154203 Binding of Pick1 and Grm7 1 0.41 1.64 1.28
82 INT138214 Mzb1 Regulation of Tac1 1 0.01 0.41 1.28
83 INT83705 Acyp2-ps1 Regulation of Positive_regulation of Casp3 1 0.17 0 1.28
84 INT112961 NGF Positive_regulation of ICAM1 1 0.40 0.96 1.28
85 INT125950 Syt17 Regulation of Trpv1 1 0.11 0.43 1.28
86 INT177232 ICAM1 Regulation of Gene_expression of Vcam1 1 0.03 5.52 1.28
87 INT22501 Binding of Calca and Pth 1 0.21 0.07 1.28
88 INT153923 Msr1 Positive_regulation of Gene_expression of Tdo2 1 0.00 0.89 1.28
89 INT169289 CNR1 Positive_regulation of EGFR 1 0.62 0.36 1.28
90 INT280480 Binding of Bdnf and Ngfr 5 0.25 3.14 1.27
91 INT113844 CDKN1A Negative_regulation of CDK2 4 0.49 1.18 1.27
92 INT121703 IL1B Positive_regulation of Gene_expression of MMP1 3 0.49 1.14 1.27
93 INT74841 Binding of Cacna1a and Ea2 2 0.01 2.33 1.27
94 INT42579 SOD1 Negative_regulation of POMC 1 0.16 0.43 1.27
95 INT34052 POMC Regulation of Gene_expression of IFNG 1 0.11 0 1.27
96 INT136644 T(1;9)27H Negative_regulation of Gene_expression of Hand1 1 0.15 1.14 1.27
97 INT195929 Binding of OPRM1 and Prkaca 1 0.02 0.33 1.27
98 INT314209 Ngf Positive_regulation of Binding of Mapk14 1 0.43 1.48 1.27
99 INT73398 Binding of Pnoc and Nr1d2 1 0.10 0 1.27
100 INT132943 Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
101 INT31773 Pdyn Positive_regulation of Nppa 1 0.12 0.13 1.27
102 INT100816 PPP1R14C Regulation of Ppp1cc 1 0.08 0 1.27
103 INT19819 Penk Regulation of Gene_expression of Ins1 1 0.05 0 1.27
104 INT51388 Binding of CSF2 and RPLP0 1 0.11 1.8 1.27
105 INT105295 WAS Regulation of PTGS1 1 0.02 0.13 1.27
106 INT71109 Binding of INSRR and MC1R 1 0.01 0 1.27
107 INT181436 Binding of Ccl2 and Eae1 1 0.05 5.14 1.27
108 INT64749 Negative_regulation of Binding of Oprm1 and Pck1 1 0.47 0.21 1.27
109 INT114925 Binding of Oprm1 and Crebbp 1 0.06 0.14 1.27
110 INT98833 Th Regulation of Gene_expression of Drd2 1 0.19 0.64 1.27
111 INT86518 Ass1 Positive_regulation of Hmox2 1 0.03 0.08 1.27
112 INT34393 Oprd1 Negative_regulation of Adcy1 1 0.36 0 1.27
113 INT343949 SERPINE2 Positive_regulation of Positive_regulation of Slco1c1 1 0.00 0.59 1.27
114 INT88449 Uncx Positive_regulation of Penk 1 0.12 0 1.27
115 INT195541 Lct Positive_regulation of Gene_expression of Grm2 1 0.02 0.4 1.27
116 INT132944 Positive_regulation of Insrr Positive_regulation of Rbm39 1 0.00 0 1.27
117 INT73598 BAX Positive_regulation of Casp1 1 0.06 0.63 1.27
118 INT71989 Binding of Pdyn and Insrr 1 0.01 0 1.27
119 INT64077 Trpv1 Positive_regulation of Kcnma1 1 0.00 0.37 1.27
120 INT162482 Binding of Agt and Vta1 1 0.23 0 1.27
121 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
122 INT30744 Sst Regulation of Cck 1 0.28 0.43 1.27
123 INT71990 Negative_regulation of Binding of Pdyn and Insrr 1 0.01 0 1.27
124 INT70226 Binding of TAC1 and B3GAT1 4 0.24 4.5 1.26
125 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
126 INT159655 Binding of BDNF and INSRR 2 0.00 1.25 1.26
127 INT70037 TNF Regulation of IL10 2 0.09 2.11 1.26
128 INT5518 Pomc Negative_regulation of Crh 2 0.36 0.42 1.26
129 INT142431 Cp Positive_regulation of Crh 1 0.31 1.49 1.26
130 INT143620 Ltp Positive_regulation of Npr1 1 0.01 0.16 1.26
131 INT119713 Negative_regulation of Slc6a3 Positive_regulation of Cpu3 1 0.39 0.71 1.26
132 INT70181 PRCP Positive_regulation of FOS 1 0.58 0.36 1.26
133 INT166413 Gprasp1 Regulation of D2Mit212 1 0.15 0.31 1.26
134 INT111211 Binding of Drd4 and Chdh 1 0.01 1.34 1.26
135 INT124099 Binding of GGT5 and RYBP 1 0.00 0.34 1.26
136 INT124767 Creb1 Regulation of Oprm1 1 0.45 0 1.26
137 INT219686 Binding of CEL and COPD 1 0.12 11.35 1.26
138 INT342990 TRPV1 Positive_regulation of Gene_expression of SFTPA1 1 0.06 1.44 1.26
139 INT207548 U Negative_regulation of Gene_expression of Oprm1 1 0.01 0.46 1.26
140 INT46022 tp Positive_regulation of SERPINB1 1 0.04 0 1.26
141 INT42580 CAT Negative_regulation of POMC 1 0.20 0.42 1.26
142 INT84886 APC Regulation of PPARD 1 0.51 1.57 1.26
143 INT114635 Hmox2 Positive_regulation of Gene_expression of Fos 1 0.47 0.88 1.26
144 INT46853 POMC Regulation of GAST 1 0.11 0.07 1.26
145 INT296796 Tbrs1 Positive_regulation of Gene_expression of TNF 1 0.00 1.58 1.26
146 INT239640 Sst Positive_regulation of Ltp 1 0.04 0.23 1.26
147 INT121464 Negative_regulation of Oprm1 Positive_regulation of Dnm2 1 0.34 0 1.26
148 INT128776 Cntn1 Positive_regulation of Gene_expression of Pde6b 1 0.02 0.55 1.26
149 INT149844 Negative_regulation of Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.26
150 INT124108 Binding of RYBP and Ccne1 1 0.09 0.34 1.26
151 INT287104 Binding of Ntrk2 and T 1 0.20 3.29 1.26
152 INT69279 Regulation of Binding of TSPO and Gabrg1 1 0.00 2.05 1.26
153 INT254355 PF4 Positive_regulation of IFNA1 1 0.04 1.23 1.26
154 INT73710 Mastl Positive_regulation of Localization of Oprl1 1 0.02 0 1.26
155 INT46021 tp Positive_regulation of Oprl1 1 0.22 0 1.26
156 INT78066 Tlr4 Positive_regulation of Localization of Il6 5 0.03 0.76 1.25
157 INT67383 Binding of OPRK1 and Pdyn 2 0.00 0 1.25
158 INT110542 SIGMAR1 Regulation of OPRM1 1 0.04 0.33 1.25
159 INT110543 SIGMAR1 Regulation of Gene_expression of OPRM1 1 0.04 0.33 1.25
160 INT155663 Positive_regulation of P2rx4 Positive_regulation of Localization of Bdnf 1 0.42 0.84 1.25
161 INT87375 Binding of Gabrg1 and Oprm1 1 0.00 0.83 1.25
162 INT211743 Positive_regulation of Binding of Pag1 and Mors1 1 0.09 0.1 1.25
163 INT162165 WDTC1 Positive_regulation of PLD2 1 0.50 0 1.25
164 INT52205 Prl Positive_regulation of Gene_expression of Penk 1 0.52 0.15 1.25
165 INT271602 Binding of Pdgfa and Pdgfrl 1 0.02 0.86 1.25
166 INT139724 PROC Positive_regulation of MAPK14 1 0.00 1.57 1.25
167 INT352269 Binding of Jund and Adora1 1 0.15 1.2 1.25
168 INT342165 Binding of Aqp1 and Nav1 1 0.25 0.57 1.25
169 INT30128 Binding of MET and Gast 1 0.06 0.18 1.25
170 INT47956 Cck Positive_regulation of Gast 1 0.02 0.09 1.25
171 INT86090 SCN5A Negative_regulation of Positive_regulation of Abat 1 0.00 0 1.25
172 INT99695 Binding of Tspo and Insrr 1 0.02 0.52 1.25
173 INT116628 St13 Regulation of Positive_regulation of P9Ehs1 1 0.00 0 1.25
174 INT317569 Prkca Positive_regulation of Phosphorylation of Src 1 0.11 0 1.25
175 INT126801 Regulation of Binding of Oprm1 and Penk 1 0.34 0.4 1.25
176 INT121000 Binding of PAG1 and Nrm 1 0.13 0.67 1.25
177 INT348380 Binding of Fdps and Lpar5 1 0.07 1.45 1.25
178 INT236835 Binding of CISH and CSF2 1 0.06 1.43 1.25
179 INT254210 Binding of Cxcr2 and Ccl2 1 0.08 2.39 1.25
180 INT74467 Adcyap1 Positive_regulation of Localization of Gh1 1 0.37 0 1.25
181 INT43446 Binding of Cpe and H3 1 0.02 0 1.25
182 INT202042 CAMK2N2 Negative_regulation of MMP9 1 0.01 0.73 1.25
183 INT169768 Binding of Slc6a4 and Mir16-1 1 0.33 0 1.25
184 INT161507 Tlr4 Positive_regulation of Gene_expression of Il1b 1 0.24 0.19 1.25
185 INT118784 Thop1 Positive_regulation of Protein_catabolism of Pax3 1 0.07 0.07 1.25
186 INT202041 CAMK2N2 Negative_regulation of PPP1R11 1 0.00 0.74 1.25
187 INT116892 Binding of TRPV1 and Phax 4 0.00 0.1 1.24
188 INT66205 TNF Positive_regulation of TNF Positive_regulation of NFKB1 4 0.41 2.74 1.24
189 INT186355 Il23a Positive_regulation of Gene_expression of Il17a 4 0.12 3 1.24
190 INT251142 Binding of Dlg4 and Grin2a 3 0.30 0.5 1.24
191 INT18324 Sst Negative_regulation of Localization of Ins1 2 0.46 1.09 1.24
192 INT88635 Ptger3 Positive_regulation of Localization of Calca 2 0.05 0 1.24
193 INT161508 Tlr4 Positive_regulation of Mapk14 2 0.19 0.46 1.24
194 INT3575 Sst Regulation of Localization of Gnrhr 2 0.24 0 1.24
195 INT305408 Binding of KCNMA1 and ST8SIA2 1 0.01 0.09 1.24
196 INT132465 Ltf Positive_regulation of Nos1 1 0.35 0.05 1.24
197 INT145315 D2Mit212 Regulation of Casp3 1 0.00 0 1.24
198 INT151444 Binding of Oprm1 and Pag1 1 0.00 1.5 1.24
199 INT45269 POMC Negative_regulation of Penk 1 0.01 0 1.24
200 INT104348 Pnoc Negative_regulation of Localization of Gnrh1 1 0.45 0 1.24
201 INT50386 Bdnf Regulation of Npy 1 0.21 0.47 1.24
202 INT202039 CAMK2N2 Negative_regulation of MMP1 1 0.00 0.73 1.24
203 INT121190 KCNMA1 Positive_regulation of Gene_expression of IL6 1 0.03 0.54 1.24
204 INT34471 Negative_regulation of Pomc Regulation of Slc3a1 1 0.05 0.12 1.24
205 INT121465 Binding of Dnm2 and Oprm1 1 0.23 0 1.24
206 INT64758 Negative_regulation of oh Negative_regulation of Gpi1 1 0.03 0 1.24
207 INT151648 TLR4 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
208 INT136257 Tff3 Regulation of SGCG 1 0.00 0.18 1.24
209 INT314198 Mapk14 Positive_regulation of Gene_expression of Trpv1 1 0.48 1.09 1.24
210 INT314212 Mapk14 Positive_regulation of Gene_expression of Agtrap 1 0.06 1.09 1.24
211 INT21858 Maoa Regulation of Gene_expression of Spna1 1 0.12 0.18 1.24
212 INT202036 CAMK2N2 Negative_regulation of MMP3 1 0.00 0.73 1.24
213 INT162163 CDKN2A Positive_regulation of PLD2 1 0.24 0 1.24
214 INT167278 Binding of OPRM1 and REST 1 0.08 0.94 1.24
215 INT158545 Binding of Trpc3 and Jph2 1 0.55 0 1.24
216 INT71070 Positive_regulation of Oprl1 Positive_regulation of Gene_expression of Cck 1 0.26 0 1.24
217 INT249014 Gabrg1 Regulation of Per2 1 0.31 0 1.24
218 INT136255 Tff3 Regulation of GRIA1 1 0.00 0.18 1.24
219 INT125857 Insrr Negative_regulation of Oprm1 1 0.01 0.27 1.24
220 INT70570 su Positive_regulation of Gh 1 0.01 0.15 1.24
221 INT151657 Vcam1 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
222 INT136250 Phosphorylation of Tff3 Regulation of Creb1 1 0.02 0.18 1.24
223 INT202040 CAMK2N2 Negative_regulation of MMP7 1 0.00 0.73 1.24
224 INT69562 Positive_regulation of AP2M1 Positive_regulation of Regulation of Adrb3 1 0.01 0.19 1.24
225 INT151658 F3 Regulation of Gene_expression of ICAM1 1 0.00 2.86 1.24
226 INT141244 Fos Regulation of Prkaca 1 0.18 0.07 1.24
227 INT145316 D2Mit212 Regulation of Positive_regulation of Casp3 1 0.00 0 1.24
228 INT283426 Binding of Lcn2 and Nt5e 1 0.08 5.8 1.24
229 INT92800 Arrb2 Negative_regulation of Oprm1 1 0.37 0.33 1.24
230 INT149845 Cxcl12 Negative_regulation of C19orf10 1 0.16 0.45 1.24
231 INT195926 Prkaca Positive_regulation of Trpv1 1 0.10 0.44 1.24
232 INT108389 IL1B Positive_regulation of ADAMTS4 1 0.51 1.19 1.24
233 INT20530 Nts Regulation of Prss12 5 0.24 0.74 1.23
234 INT63864 Oprd1 Regulation of Localization of Prl 2 0.16 0 1.23
235 INT7887 Oprl1 Regulation of Localization of Oxt 2 0.16 0 1.23
236 INT172141 IL10 Negative_regulation of Gene_expression of HLA-DRA 2 0.14 0.89 1.23
237 INT162343 Positive_regulation of KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
238 INT199593 Binding of TRPV1 and Myoz1 1 0.10 1.7 1.23
239 INT71443 CSAD Positive_regulation of Gene_expression of Fos 1 0.58 0.81 1.23
240 INT259229 Positive_regulation of Binding of Oprm1 and Flna 1 0.02 0 1.23
241 INT247924 Slc12a5 Regulation of Gene_expression of Slc12a2 1 0.25 1.43 1.23
242 INT45891 Tyms Positive_regulation of Localization of Acot1 1 0.02 0 1.23
243 INT123453 Binding of POMC and Penk 1 0.01 0.31 1.23
244 INT162344 KCNMA1 Positive_regulation of ACE 1 0.06 1.25 1.23
245 INT50385 Bdnf Positive_regulation of Pomc 1 0.22 0.47 1.23
246 INT188702 St6galnac2 Positive_regulation of Gene_expression of Stab1 1 0.00 5.09 1.23
247 INT150595 Binding of Oprk1 and Insrr 1 0.01 0.07 1.23
248 INT42806 Binding of CCT6A and PENK 1 0.02 0 1.23
249 INT274948 Binding of Dh and Ltp 1 0.11 0.55 1.23
250 INT136256 Creb1 Regulation of SGCG 1 0.26 0.18 1.23
251 INT136258 Creb1 Regulation of GRIA1 1 0.26 0.18 1.23
252 INT249487 Binding of Ephb1 and Src 1 0.17 0.74 1.23
253 INT21859 Maoa Regulation of Spna1 1 0.12 0.18 1.23
254 INT168459 Sult1a1 Negative_regulation of Gene_expression of Arr3 1 0.05 2.98 1.23
255 INT341218 Binding of Eif4e and Eif4ebp1 1 0.19 2.65 1.23
256 INT247926 Slc12a5 Regulation of Cl 1 0.01 1.43 1.23
257 INT190130 Binding of CPOX and MRXS5 1 0.00 1.4 1.23
258 INT136249 Drd1a Positive_regulation of Phosphorylation of Tff3 1 0.01 0.18 1.23
259 INT34473 Pomc Regulation of Slc3a1 1 0.03 0.07 1.23
260 INT310066 Negative_regulation of Pain1 Positive_regulation of Faah 1 0.03 1.32 1.23
261 INT21857 Maoa Regulation of Ap3d1 1 0.12 0.18 1.23
262 INT184919 Binding of da and Slc6a3 1 0.12 0.33 1.23
263 INT58140 Binding of AP2M1 and Oprm1 1 0.01 0.4 1.23
264 INT121189 KCNMA1 Positive_regulation of IL6 1 0.04 0.54 1.23
265 INT147033 Positive_regulation of Binding of Sds and Accn3 1 0.13 0.73 1.23
266 INT237207 LGALS4 Regulation of Localization of Ik 1 0.00 0.9 1.23
267 INT310069 Negative_regulation of Pain1 Positive_regulation of Mgll 1 0.02 1.32 1.23
268 INT311914 Il1 Negative_regulation of Gene_expression of Col2a1 1 0.01 1.94 1.23
269 INT247925 Slc12a2 Regulation of Cl 1 0.01 1.44 1.23
270 INT197092 TNF Regulation of VEGFA 4 0.21 2.78 1.22
271 INT83422 Binding of FANCB and IGHG3 3 0.12 5.09 1.22
272 INT15578 GNRH1 Regulation of Localization of Lhb 3 0.07 0 1.22
273 INT13603 Binding of NCF4 and Nrm 2 0.40 0.21 1.22
274 INT42554 Oprl1 Regulation of Npr1 2 0.06 0 1.22
275 INT131195 Creb1 Positive_regulation of Positive_regulation of Drd1a 2 0.27 0.61 1.22
276 INT40900 PDYN Regulation of Localization of POMC 2 0.07 0.56 1.22
277 INT103031 Calca Positive_regulation of Ptgs1 2 0.46 0.98 1.22
278 INT145317 D2Mit212 Positive_regulation of Casp3 1 0.01 0 1.22
279 INT334129 Acsm3 Positive_regulation of Gene_expression of Icam1 1 0.22 2.89 1.22
280 INT121729 Negative_regulation of Ngf Positive_regulation of Ephb1 1 0.24 0.69 1.22
281 INT52955 Binding of Slc6a3 and Pdpn 1 0.17 1.11 1.22
282 INT256298 Binding of Creb1 and Ephb1 1 0.16 1.27 1.22
283 INT153215 Htr5b Positive_regulation of Pag1 1 0.01 0.57 1.22
284 INT139191 Binding of Fas and RFFL 1 0.00 0.61 1.22
285 INT76165 IGKV2-30 Positive_regulation of Phosphorylation of Oprm1 1 0.00 0.08 1.22
286 INT7200 Reg3b Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.01 0 1.22
287 INT75229 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.44 0 1.22
288 INT240095 Binding of PDYN and Oprk1 1 0.52 1.3 1.22
289 INT151454 Binding of Calca and Insrr 1 0.02 0.31 1.22
290 INT350862 Hist1h1t Regulation of Kcnj5 1 0.02 1.35 1.22
291 INT310068 Pain1 Positive_regulation of Faah 1 0.03 1.3 1.22
292 INT253999 Binding of Cxcl12 and Mif 1 0.41 2.26 1.22
293 INT7198 Magt1 Negative_regulation of Syt17 Positive_regulation of Ctsb 1 0.03 0 1.22
294 INT76163 Prkaca Positive_regulation of Phosphorylation of Oprm1 1 0.02 0.08 1.22
295 INT77806 Edn1 Regulation of Gene_expression of Ptgs2 1 0.29 1.24 1.22
296 INT197231 Grik1 Regulation of Gabrg1 1 0.19 0.13 1.22
297 INT260833 Binding of NRP2 and Flt1 1 0.00 3.61 1.22
298 INT62596 Binding of Edn1 and Nppa 1 0.27 1.77 1.22
299 INT187174 RPS3AP9 Negative_regulation of MMP2 1 0.00 0.9 1.22
300 INT159837 Trim2 Negative_regulation of Transcription of Fos 1 0.10 1.92 1.22
301 INT147032 Binding of Sds and Accn3 1 0.09 0.73 1.22
302 INT298260 Binding of Runx3 and Pou4f1 1 0.52 2.08 1.22
303 INT131807 Bpifa2 Positive_regulation of Localization of Tnf 1 0.32 2.09 1.22
304 INT56881 Ppbp Regulation of Vip 1 0.00 0 1.22
305 INT70028 LTA Regulation of PRF1 1 0.02 1.42 1.21
306 INT70036 LTA Regulation of Negative_regulation of IL10 1 0.03 1.42 1.21
307 INT87586 RPL7AP5 Negative_regulation of Gene_expression of Calca 1 0.00 0.05 1.21
308 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
309 INT285185 Binding of Ca2 and Cd2 1 0.25 0.24 1.21
310 INT261410 Slc7a2 Positive_regulation of Ltp 1 0.06 0.08 1.21
311 INT79471 Mgat4a Regulation of Calca 1 0.06 1.09 1.21
312 INT70035 TNF Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
313 INT70039 IL1B Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
314 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
315 INT342988 HCL1 Positive_regulation of TRPV1 1 0.04 1.15 1.21
316 INT70032 TNF Regulation of PRF1 1 0.05 1.42 1.21
317 INT7186 Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
318 INT70042 LTA Regulation of Negative_regulation of PRF1 1 0.02 1.42 1.21
319 INT59707 PSENEN Regulation of Negative_regulation of YY1 1 0.12 0.07 1.21
320 INT87585 RPL7AP5 Negative_regulation of Calca 1 0.00 0.05 1.21
321 INT351379 Ngf Positive_regulation of Binding of Ngf and Ntrk1 1 0.38 0.63 1.21
322 INT70040 TNF Regulation of Negative_regulation of IL10 1 0.09 1.42 1.21
323 INT70033 IL6 Regulation of PRF1 1 0.03 1.42 1.21
324 INT70038 IL1B Regulation of PRF1 1 0.05 1.42 1.21
325 INT121724 Ngf Positive_regulation of Ephb1 1 0.40 0.68 1.21
326 INT200455 OPRK1 Positive_regulation of Gene_expression of CCL2 1 0.19 0.07 1.21
327 INT181490 Tryptase Positive_regulation of F2rl1 1 0.13 1.83 1.21
328 INT328743 TNF Positive_regulation of Mapk14 1 0.04 1.4 1.21
329 INT70031 IL1B Regulation of Negative_regulation of PRF1 1 0.05 1.42 1.21
330 INT310067 Pain1 Positive_regulation of Mgll 1 0.02 1.29 1.21
331 INT164365 Positive_regulation of Binding of NLRP1 and VTA1 1 0.14 0.6 1.21
332 INT82754 Cck Positive_regulation of Positive_regulation of Pomc 1 0.39 0.3 1.21
333 INT62018 CSF2 Regulation of ACOT1 1 0.12 0.47 1.21
334 INT166388 Binding of Gnb2l1 and Mapk1 1 0.49 0.49 1.21
335 INT7184 Negative_regulation of Trib3 Negative_regulation of Positive_regulation of Ctsb 1 0.03 0 1.21
336 INT329956 Binding of IL2 and IL23R 1 0.33 4.58 1.21
337 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
338 INT70030 IL1B Regulation of IL10 1 0.07 1.42 1.21
339 INT301166 LRP2 Regulation of TRD@ 1 0.12 1.93 1.21
340 INT96261 Positive_regulation of Pik3cd Positive_regulation of Plcg2 1 0.02 0 1.21
341 INT70047 IL6 Regulation of Negative_regulation of PRF1 1 0.03 1.42 1.21
342 INT62019 CSF2 Regulation of ELANE 1 0.03 0.47 1.21
343 INT70041 LTA Regulation of IL10 1 0.03 1.42 1.21
344 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
345 INT142154 Trpv1 Positive_regulation of Gene_expression of Il2 1 0.22 0 1.21
346 INT110435 Positive_regulation of Grm8 Positive_regulation of Localization of Ca2 1 0.38 0 1.21
347 INT70029 IL6 Regulation of Negative_regulation of IL10 1 0.05 1.42 1.21
348 INT140172 Binding of Nqo1 and IgG 5 0.17 6.68 1.2
349 INT62368 Gal Positive_regulation of Localization of LH 3 0.36 0 1.2
350 INT224410 Binding of CRP and CIMT 3 0.42 10.46 1.2
351 INT194861 Binding of IL1B and IL1R1 2 0.01 1.55 1.2
352 INT124874 Gnat3 Positive_regulation of Localization of Calca 2 0.08 0.75 1.2
353 INT210982 Binding of Cnr1 and Cfp 2 0.22 1.27 1.2
354 INT112105 Negative_regulation of Dlg2 Negative_regulation of Gene_expression of Grin2b 2 0.40 0.89 1.2
355 INT209926 IL1B Regulation of PPARA 1 0.21 2.45 1.2
356 INT204558 Tens1 Negative_regulation of Pdgfc 1 0.01 0.25 1.2
357 INT140238 HELQ Regulation of MC1R 1 0.01 0.5 1.2
358 INT194619 Il15 Positive_regulation of Gene_expression of TNF 1 0.24 2.23 1.2
359 INT98832 Th Regulation of Dbh 1 0.32 0.53 1.2
360 INT281373 Tcf21 Regulation of Fig4 1 0.03 0.67 1.2
361 INT17601 Binding of POMC and Oprl1 1 0.01 0 1.2
362 INT105918 Binding of FUT1 and SLC9A3R2 1 0.00 0.14 1.2
363 INT108065 Negative_regulation of Binding of Ngf and IgG-2a 1 0.01 2.38 1.2
364 INT21424 Binding of Penk and Gtpbp4 1 0.02 0.16 1.2
365 INT131462 NGF Regulation of Localization of INS 1 0.40 0.97 1.2
366 INT90644 Slc6a3 Positive_regulation of Th 1 0.51 0 1.2
367 INT187172 RPS3AP9 Negative_regulation of MMP9 1 0.00 0.89 1.2
368 INT63384 Binding of Cnr1 and Insrr 1 0.03 0.24 1.2
369 INT108067 Negative_regulation of Binding of NTRK1 and Ngf 1 0.06 2.38 1.2
370 INT328742 Il1 Positive_regulation of Mapk14 1 0.01 1.4 1.2
371 INT299299 VEGFA Positive_regulation of SRC 1 0.20 0.91 1.2
372 INT166301 Adrbk1 Positive_regulation of Localization of Trpv1 1 0.45 1.17 1.2
373 INT81097 Akr1d1 Regulation of Localization of Abat 1 0.00 0 1.2
374 INT7202 Uba3 Negative_regulation of Abl2 Positive_regulation of Ctsb 1 0.00 0 1.2
375 INT228681 Fkbp4 Negative_regulation of Trib3 1 0.00 0.57 1.2
376 INT334351 Bdnf Regulation of Positive_regulation of Ephb1 1 0.18 1.27 1.2
377 INT88193 Binding of IL2 and IL4 1 0.13 1.7 1.2
378 INT108469 Tacr1 Regulation of Transcription of Drd2 1 0.07 0.14 1.2
379 INT172500 Ednra Positive_regulation of Coc 1 0.01 1 1.2
380 INT133046 TNF Positive_regulation of Positive_regulation of NFKB1 5 0.54 3.23 1.19
381 INT83428 Binding of ADIPOQ and FRTS 3 0.18 2.02 1.19
382 INT281077 Binding of Gria2 and Gria3 2 0.24 0.35 1.19
383 INT29714 Crh Regulation of Localization of LH 2 0.26 0 1.19
384 INT113242 TNF Regulation of Transcription of OPRM1 2 0.45 1.53 1.19
385 INT162419 Binding of Abpa and Cftr 1 0.04 1.66 1.19
386 INT70288 Negative_regulation of Atxn2l Positive_regulation of Racgap1 1 0.02 0.3 1.19
387 INT281383 FSCN1 Positive_regulation of Fig4 1 0.02 0.44 1.19
388 INT93294 Ngf Regulation of Transcription of Trpv1 1 0.01 0.36 1.19
389 INT281379 Tcf21 Regulation of FSCN1 1 0.01 0.66 1.19
390 INT298454 Prkcg Positive_regulation of Phosphorylation of Adarb1 1 0.00 0.41 1.19
391 INT3302 Penk Positive_regulation of Slc43a3 1 0.01 0.09 1.19
392 INT109380 Binding of Adarb1 and Fos 1 0.02 0.38 1.19
393 INT25660 Binding of Penk and Pag1 1 0.01 0.67 1.19
394 INT169802 Negative_regulation of Adrbk1 Positive_regulation of Positive_regulation of Rapgef3 1 0.44 0.75 1.19
395 INT108064 Binding of Ngf and IgG-2a 1 0.01 2.36 1.19
396 INT65203 OPRL1 Negative_regulation of ADCY1 1 0.19 0 1.19
397 INT124157 Oprm1 Negative_regulation of Gnb5 1 0.25 0.4 1.19
398 INT75483 Binding of SGCG and TGFB1 1 0.52 2.27 1.19
399 INT139736 Htr1a Positive_regulation of Mapk3 1 0.54 0.13 1.19
400 INT35459 POMC Negative_regulation of Gene_expression of IL16 1 0.45 0 1.19
401 INT184402 Binding of HLA-DRB4 and HLA-E 1 0.00 3.1 1.19
402 INT140010 Avp Regulation of Gene_expression of Penk 1 0.25 0.58 1.19
403 INT142075 IL4 Negative_regulation of Binding of IDO1 1 0.02 2.07 1.19
404 INT142077 TGFB1 Negative_regulation of Binding of IDO1 1 0.15 2.07 1.19
405 INT247469 RCT Regulation of OAP 1 0.02 1.8 1.19
406 INT133496 Binding of Oprm1 and Cckbr 1 0.15 0 1.19
407 INT116730 Rac1 Regulation of Localization of Calca 1 0.13 1.32 1.19
408 INT49955 OPRM1 Positive_regulation of ADCY1 1 0.21 0.31 1.19
409 INT256297 Binding of Creb1 and Insrr 1 0.00 1.22 1.19
410 INT57824 Binding of Trim13 and Slc25a2 1 0.01 0.08 1.19
411 INT351715 Pax3 Negative_regulation of Adarb1 1 0.00 0 1.19
412 INT321475 Slc6a2 Positive_regulation of Ubqln1 1 0.00 0.38 1.19
413 INT94091 Binding of Pnoc and Tbce 1 0.03 0.19 1.19
414 INT256295 Binding of Creb1 and Grin2b 1 0.11 1.21 1.19
415 INT55162 Binding of NFKB1 and RELA 10 0.30 2.82 1.18
416 INT201067 Binding of Edn1 and Ednra 2 0.18 1.36 1.18
417 INT75126 Pnoc Regulation of Localization of Avp 2 0.26 0.24 1.18
418 INT27621 Avp Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18
419 INT330379 Gene_expression of IL10 Negative_regulation of Positive_regulation of MAPK14 1 0.00 1.95 1.18
420 INT351373 Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
421 INT349587 Binding of Aap and Csf2 1 0.04 0.41 1.18
422 INT122370 Positive_regulation of Tacr1 Positive_regulation of Ngf 1 0.30 0.17 1.18
423 INT170655 Binding of Csf2 and Ngf 1 0.36 1.25 1.18
424 INT93435 Binding of Casp3 and Cckbr 1 0.06 0.15 1.18
425 INT152428 Ghrh Positive_regulation of Pde6b 1 0.07 0.5 1.18
426 INT264333 IL-17 Positive_regulation of Gene_expression of Mmp1a 1 0.05 2.88 1.18
427 INT314196 Ngf Positive_regulation of Tnf 1 0.50 1.98 1.18
428 INT203168 PTGER2 Negative_regulation of Gene_expression of ALOX5AP 1 0.03 2.4 1.18
429 INT120205 Binding of App and Ern1 1 0.05 2.55 1.18
430 INT194403 Negative_regulation of Binding of CALCA and DCLK3 1 0.22 0 1.18
431 INT220751 EGF Regulation of GOPC 1 0.08 0 1.18
432 INT98908 Binding of NTRK1 and PKLR 1 0.41 1.95 1.18
433 INT121191 KCNMA1 Positive_regulation of Phosphorylation of MAPK1 1 0.06 0.61 1.18
434 INT20929 Binding of Trim13 and Vas1 1 0.10 0 1.18
435 INT107579 Kitl Negative_regulation of Grin2a 1 0.10 1.02 1.18
436 INT13203 Oprd1 Negative_regulation of Akr1d1 1 0.01 0 1.18
437 INT351378 Gene_expression of Ngf Positive_regulation of Ntrk1 1 0.35 0.41 1.18
438 INT27622 LOC360919 Positive_regulation of Protein_catabolism of Mbis1 1 0.00 0 1.18
439 INT220752 Negative_regulation of EGF Regulation of NAV1 1 0.26 0 1.18
440 INT34661 Abat Positive_regulation of Localization of Pomc 1 0.04 0 1.18
441 INT261617 SNRNP70 Regulation of Comt 1 0.01 0.4 1.18
442 INT73075 Adarb1 Regulation of Fos 1 0.01 0.07 1.18
443 INT32871 Binding of Insrr and Adarb1 1 0.01 0 1.18
444 INT98906 Positive_regulation of Binding of NTRK1 and PKLR 1 0.56 1.95 1.18
445 INT220753 Negative_regulation of EGF Regulation of GOPC 1 0.08 0 1.18
446 INT228680 Fkbp1a Negative_regulation of Trib3 1 0.01 0.56 1.18
447 INT150835 Gper Positive_regulation of Localization of Prkce 1 0.15 0.62 1.18
448 INT49956 OPRM1 Positive_regulation of SGCG 1 0.53 0.3 1.18
449 INT351377 Gene_expression of Ngf Positive_regulation of Gene_expression of Ntrk1 1 0.35 0.41 1.18
450 INT203016 CCK Positive_regulation of Localization of PYY 3 0.68 1.19 1.17
451 INT169082 Binding of GRIA1 and MOCOS 2 0.07 1.23 1.17
452 INT148437 Binding of Bdnf and Ngf 2 0.32 1.9 1.17
453 INT146879 CRX Regulation of NMS 2 0.02 1.86 1.17
454 INT148435 Binding of Bdnf and Gdnf 2 0.35 1.9 1.17
455 INT141245 Prkaca Regulation of Gene_expression of Th 1 0.15 0.17 1.17
456 INT85780 Prkaca Regulation of Prkcg 1 0.29 0.47 1.17
457 INT66488 Binding of Oprl1 and Cbm4 1 0.01 0 1.17
458 INT62382 Binding of IGHG3 and SMPD2 1 0.02 0.37 1.17
459 INT141246 Trib3 Regulation of Gene_expression of Th 1 0.02 0.17 1.17
460 INT153589 Binding of PRKCI and Oprm1 1 0.06 0 1.17
461 INT225067 Binding of ETF1 and IGHG3 1 0.03 4.52 1.17
462 INT92995 SFTPA1 Regulation of Gene_expression of CALM1 1 0.06 0.93 1.17
463 INT62379 Negative_regulation of Binding of IGHG3 and SMPD2 1 0.03 0.37 1.17
464 INT140022 Avp Regulation of Localization of Pag1 1 0.01 0.57 1.17
465 INT182159 Binding of HGF and DCPS 1 0.01 2.5 1.17
466 INT134871 Negative_regulation of Binding of Calm3 and IQCJ 1 0.00 0.41 1.17
467 INT220748 EGF Regulation of NAV1 1 0.28 0 1.17
468 INT25112 RYBP Negative_regulation of Binding of PLEKHM1 1 0.01 0 1.17
469 INT180814 Binding of Ret and Gdnf 1 0.01 1.31 1.17
470 INT57822 Binding of Slc25a2 and Atxn2l 1 0.00 0.08 1.17
471 INT146352 Binding of Rgs14 and Mors1 1 0.23 0.27 1.17
472 INT57823 Binding of Trim13 and Atxn2l 1 0.00 0.08 1.17
473 INT153588 Binding of HINT1 and Oprm1 1 0.06 0 1.17
474 INT131887 Nr3c1 Regulation of Gene_expression of Prkcg 1 0.01 0 1.17
475 INT169557 Cacna1h Positive_regulation of Mapk1 1 0.07 0.91 1.17
476 INT60990 Bdnf Negative_regulation of Th 1 0.15 0 1.17
477 INT124435 Gene_expression of Chrna9 Positive_regulation of Phosphorylation of Creb1 1 0.11 0.6 1.17
478 INT349586 Aap Regulation of Gene_expression of Ros1 1 0.03 0.56 1.17
479 INT30871 Abat Regulation of Localization of Sst 1 0.13 0 1.17
480 INT238916 CNR1 Positive_regulation of Phosphorylation of MAPK1 1 0.19 1.61 1.17
481 INT207116 F2 Positive_regulation of F2r 5 0.12 2.16 1.16
482 INT8308 Gnrh1 Regulation of Localization of LH 4 0.27 0 1.16
483 INT289465 IRF6 Positive_regulation of IL1B 3 0.05 0.9 1.16
484 INT13205 Oprd1 Negative_regulation of Npr1 2 0.01 0 1.16
485 INT43509 Avp Positive_regulation of Localization of POMC 2 0.13 1.26 1.16
486 INT287749 Dmbx1 Positive_regulation of Gene_expression of Lpar1 1 0.41 0.82 1.16
487 INT150191 CEACAM3 Positive_regulation of Gene_expression of FOS 1 0.34 0.14 1.16
488 INT111221 MMEL1 Negative_regulation of HMOX1 1 0.01 1 1.16
489 INT93290 Ngf Regulation of Transcription of Trpv1 1 0.02 0.34 1.16
490 INT155892 Nps Negative_regulation of Casp3 1 0.27 0.06 1.16
491 INT353338 F2r Positive_regulation of Localization of Mif 1 0.68 1.25 1.16
492 INT123260 Binding of Gabrg2 and Serpini1 1 0.02 0.63 1.16
493 INT33605 DFP Positive_regulation of Cpe 1 0.16 0 1.16
494 INT335435 Ngf Positive_regulation of Ltb4r 1 0.52 1.06 1.16
495 INT195117 Ptgs2 Positive_regulation of Gene_expression of Il6 1 0.10 3.26 1.16
496 INT189017 Binding of Pax3 and Lmna 1 0.14 0.42 1.16
497 INT65373 Notch1 Regulation of Oprd1 1 0.09 0 1.16
498 INT93289 Ngf Regulation of Trpv1 1 0.05 0.34 1.16
499 INT206766 Positive_regulation of Ltp Positive_regulation of Positive_regulation of Nkx1-1 1 0.01 0.22 1.16
500 INT95045 Binding of Commd3 and Oprl1 1 0.34 0 1.16
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