G:10558

Official Symbol SPTLC1 Aliases HSAN, HSN1, LBC1, LCB1, SPT1, SPTI, HSAN1, hLCB1, MGC14645 EntrezGene 10558 UniProt Coming Soon

Unique Molecular Interactions 12 Total Molecular Interactions 15 Total Single Events 51 Unique Interaction Partners 12

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to SPTLC1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to SPTLC1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to SPTLC1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT110835	Binding of SPTLC2 and SPTLC1	2	0.42	1.36	0.68
2	INT329410	Binding of SPTLC1 and Spt	1	0.04	1	0.35
3	INT229785	Binding of RAB7A and SPTLC1	1	0.40	1.5	0.27
4	INT234831	Binding of SPTLC1 and Abo	1	0.00	1.61	0.23
5	INT329409	Binding of SPTLC1 and Dstn	1	0.05	1.3	0.23
6	INT157212	Binding of SPTLC1 and WNK1	1	0.07	0.67	0.22
7	INT157215	Binding of SGCG and SPTLC1	1	0.32	0.67	0.22
8	INT260070	Binding of PHF2 and SPTLC1	1	0.17	1.93	0.1
9	INT122927	Ntrk1 Positive_regulation of SPTLC1	1	0.00	0.65	0.09
10	INT314266	SUPT4H1 Positive_regulation of SPTLC1	1	0.02	0.13	0.03
11	INT295617	UBXN11 Negative_regulation of SPTLC1	1	0.03	0.57	0
12	INT110836	Binding of AGXT and SPTLC1	1	0.30	0.11	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 10558. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 10558. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT91100	Binding of SPTLC1	10	0.47	12.85	5.71
2	INT229788	Negative_regulation of SPTLC1	1	0.38	4.82	3.53
3	INT81955	Positive_regulation of SPTLC1	12	0.70	10.25	3.12
4	INT229793	Negative_regulation of Positive_regulation of SPTLC1	1	0.43	1.49	1.17
5	INT80338	Gene_expression of SPTLC1	10	0.78	4.06	1.09
6	INT229786	Transcription of SPTLC1	1	0.60	0.78	0.71
7	INT80335	Localization of SPTLC1	4	0.75	0.61	0.65
8	INT94146	Regulation of SPTLC1	2	0.51	2.39	0.36
9	INT81956	Positive_regulation of Protein_catabolism of SPTLC1	1	0.06	0.16	0
10	INT81957	Protein_catabolism of SPTLC1	1	0.10	0.15	0