G:1493

Official Symbol CTLA4 Aliases CD, GSE, GRD4, ICOS, CD152, CTLA-4, IDDM12, CELIAC3 EntrezGene 1493 UniProt Coming Soon

Unique Molecular Interactions 21 Total Molecular Interactions 84 Total Single Events 134 Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to CTLA4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to CTLA4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to CTLA4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT149117	Binding of CD80 and CTLA4	31	0.52	12.7	7.73
2	INT155484	Binding of CD86 and CTLA4	15	0.52	8.85	6.09
3	INT186126	Binding of CD28 and CTLA4	9	0.52	4.13	3.12
4	INT165200	Binding of CTLA4 and Crp	1	0.09	1.64	1.91
5	INT139069	Binding of CTLA4 and Cd86	3	0.16	0.65	0.7
6	INT299793	Positive_regulation of Binding of CD86 and CTLA4	1	0.17	1.64	0.63
7	INT299792	Positive_regulation of Binding of CD80 and CTLA4	1	0.17	1.63	0.63
8	INT249624	Negative_regulation of Binding of CD86 and CTLA4	1	0.47	0.57	0.55
9	INT299785	CTLA4 Negative_regulation of Binding of CD28	2	0.17	1.8	0.5
10	INT157657	Binding of CTLA4 and FCGR1A	1	0.01	0.07	0.4
11	INT139068	Binding of CTLA4 and Cd80	1	0.00	0.33	0.33
12	INT299791	Negative_regulation of Binding of CD28 and CTLA4	1	0.18	0.77	0.32
13	INT186127	CTLA4 Negative_regulation of CD28	1	0.19	0.74	0.32
14	INT259936	CTLA4 Regulation of PTPN22	1	0.45	1.64	0.28
15	INT333549	Binding of CTLA4 and PDCD1	1	0.36	1.2	0.27
16	INT252367	Binding of RUNX1 and CTLA4	1	0.02	0.48	0.18
17	INT299763	Binding of APC and CTLA4 Positive_regulation of Ido1	1	0.11	0.31	0.14
18	INT293312	CTLA4 Negative_regulation of Binding of CD28 and CD80	1	0.01	0.29	0.12
19	INT299754	Binding of APC and CTLA4	2	0.08	0.97	0.11
20	INT283460	Binding of CTLA4 and DLAT	1	0.06	3.14	0.09
21	INT145987	Binding of CTLA4 and Aip	1	0.08	0.61	0.09
22	INT259938	Binding of CTLA4 and PTPN22	1	0.36	0.85	0.08
23	INT149120	Binding of CTLA4 and Cd28	1	0.03	0.14	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 1493. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 1493. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT148207	Gene_expression of CTLA4	53	0.77	29.13	12.07
2	INT132278	Binding of CTLA4	32	0.39	18.69	8.17
3	INT67796	Negative_regulation of CTLA4	13	0.39	8.36	2.39
4	INT143083	Regulation of CTLA4	4	0.25	1.06	1.36
5	INT145986	Positive_regulation of CTLA4	8	0.56	2.66	0.82
6	INT264192	Positive_regulation of Gene_expression of CTLA4	6	0.43	2.06	0.45
7	INT160874	Protein_catabolism of CTLA4	1	0.88	0.56	0.39
8	INT294135	Positive_regulation of Positive_regulation of CTLA4	1	0.25	0.45	0.32
9	INT173956	Negative_regulation of Gene_expression of CTLA4	3	0.37	0.91	0.2
10	INT296068	Regulation of Gene_expression of CTLA4	1	0.16	0.22	0.2
11	INT277827	Localization of CTLA4	1	0.65	0	0.18
12	INT277819	Positive_regulation of Localization of CTLA4	1	0.43	0	0.18
13	INT149118	Regulation of Binding of CTLA4	1	0.33	0.32	0.07
14	INT276341	Transcription of CTLA4	1	0.30	1.04	0.07
15	INT283499	Negative_regulation of Positive_regulation of CTLA4	1	0.09	1.02	0.05
16	INT283512	Positive_regulation of Binding of CTLA4	1	0.11	1.03	0.03