G:171115

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Official Symbol Pde5a
Aliases PDE5A2
EntrezGene 171115
UniProt Coming Soon
Unique Molecular Interactions 24
Total Molecular Interactions 27
Total Single Events 226
Unique Interaction Partners 21

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Pde5a. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Pde5a. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Pde5a. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT291578 Negative_regulation of Pde12 Positive_regulation of Pde5a 1 0.03 1.11 1.67
2 INT291583 GUCY2C Regulation of Pde5a 1 0.00 1.12 1.45
3 INT257304 Pde5a Positive_regulation of Oprd1 1 0.15 0.48 0.89
4 INT291581 Pde5a Regulation of Localization of Abat 1 0.03 0 0.83
5 INT257302 Cnp Regulation of Protein_catabolism of Pde5a 1 0.05 0.49 0.7
6 INT291579 Pde12 Regulation of Binding of Pde5a 1 0.02 0.41 0.6
7 INT291580 Pde5a Regulation of Abat 1 0.04 0.39 0.48
8 INT316929 Pde5a Regulation of Ephb1 1 0.03 0.17 0.27
9 INT280181 Pde5a Positive_regulation of Regulation of Cpox 1 0.00 0.16 0.26
10 INT222489 Npr2 Positive_regulation of Pde5a 1 0.00 0.16 0.07
11 INT222429 Nps Positive_regulation of Pde5a 1 0.00 0.16 0.07
12 INT337608 Pde5a Regulation of Cnga1 1 0.00 0 0.04
13 INT263197 Binding of PDE3A and Pde5a 1 0.03 0.18 0.04
14 INT263198 Pde5a Negative_regulation of PDE4A 1 0.09 0.16 0.03
15 INT331897 Binding of PDE5A and Pde5a 1 0.02 0.64 0.03
16 INT222556 Pde5a Regulation of Localization of LH 1 0.00 0.06 0
17 INT263181 Binding of Pde1a and Pde5a 1 0.03 0 0
18 INT98237 Pde2a Negative_regulation of LOC360919 Positive_regulation of Pde5a 1 0.00 0.33 0
19 INT98236 LOC360919 Positive_regulation of Pde5a 1 0.00 0.33 0
20 INT268021 Pde5a Positive_regulation of Kcnj5 1 0.01 0 0
21 INT263183 Binding of Pde1b and Pde5a 1 0.03 0 0
22 INT268052 Pde5a Positive_regulation of Positive_regulation of PRKG1 1 0.00 0 0
23 INT268022 Pde5a Positive_regulation of Gene_expression of Kcnj5 1 0.01 0 0
24 INT222471 Gnrh1 Positive_regulation of Pde5a 1 0.00 0.07 0
25 INT98235 Pde5a Negative_regulation of Pdpk1 1 0.00 0.32 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 171115. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 171115. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT109110 Positive_regulation of Pde5a 29 0.63 11.16 16.65
2 INT94861 Gene_expression of Pde5a 40 0.69 14.73 13.27
3 INT94859 Negative_regulation of Pde5a 67 0.43 33.66 10.28
4 INT94862 Positive_regulation of Gene_expression of Pde5a 10 0.20 4.23 5.18
5 INT131472 Regulation of Pde5a 11 0.42 6.95 3.06
6 INT136675 Transcription of Pde5a 6 0.63 4.74 2.71
7 INT94860 Negative_regulation of Gene_expression of Pde5a 2 0.33 3.2 2.64
8 INT257298 Regulation of Positive_regulation of Pde5a 1 0.19 2.03 2.54
9 INT257299 Binding of Pde5a 14 0.27 4.31 2.45
10 INT257301 Protein_catabolism of Pde5a 5 0.30 1.97 2.26
11 INT165648 Negative_regulation of Transcription of Pde5a 1 0.41 3.6 1.93
12 INT291576 Positive_regulation of Protein_catabolism of Pde5a 1 0.12 1.15 1.43
13 INT165644 Regulation of Transcription of Pde5a 1 0.44 1.65 0.91
14 INT164144 Phosphorylation of Pde5a 4 0.19 1.15 0.87
15 INT165645 Positive_regulation of Negative_regulation of Pde5a 3 0.37 1.58 0.74
16 INT165647 Negative_regulation of Negative_regulation of Pde5a 1 0.31 1.22 0.67
17 INT165646 Positive_regulation of Transcription of Pde5a 1 0.33 1.21 0.66
18 INT291577 Positive_regulation of Phosphorylation of Pde5a 1 0.12 0.35 0.48
19 INT183429 Localization of Pde5a 5 0.56 1.61 0.25
20 INT261276 Positive_regulation of Positive_regulation of Pde5a 1 0.26 0.07 0.21
21 INT261275 Negative_regulation of Localization of Pde5a 2 0.31 1.11 0.18
22 INT261274 Negative_regulation of Protein_catabolism of Pde5a 1 0.20 0.18 0.09
23 INT183435 Regulation of Localization of Pde5a 1 0.34 0.35 0.04
24 INT263185 Regulation of Gene_expression of Pde5a 1 0.12 0.19 0.03
25 INT268038 Regulation of Negative_regulation of Pde5a 1 0.03 0 0
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