G:17127

Official Symbol Smad3 Aliases Madh3, AU022421 EntrezGene 17127 UniProt Coming Soon

Unique Molecular Interactions 19 Total Molecular Interactions 41 Total Single Events 87 Unique Interaction Partners 13

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Smad3. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Smad3. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Smad3. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT343913	Binding of FOS and Smad3	1	0.19	0.92	0.54
2	INT311916	Smad3 Negative_regulation of Gene_expression of Mmp13	1	0.12	0.27	0.06
3	INT353294	Binding of Smad2 and Smad3	1	0.15	0.08	0.04
4	INT353295	Binding of Smad3 and Smad4	1	0.17	0.08	0.04
5	INT254852	Binding of Col7a1 and Smad3	1	0.01	0.57	0.03
6	INT269943	Sox17 Regulation of Binding of Smad3	1	0.37	0.12	0
7	INT254849	Negative_regulation of Rhoa Positive_regulation of Phosphorylation of Smad3	1	0.11	0.45	0
8	INT269937	Binding of Smad3 and Mgst1	1	0.09	0	0
9	INT269919	Sox17 Negative_regulation of Binding of Smad3	1	0.36	0	0
10	INT269924	Smad3 Regulation of Gene_expression of Cdkn2b	1	0.23	0.26	0
11	INT269955	Positive_regulation of Binding of Smad3 and Sox17	1	0.39	0.05	0
12	INT254863	Tgfb1 Positive_regulation of Transcription of Smad3	1	0.03	0.23	0
13	INT254857	Tgfb1 Positive_regulation of Phosphorylation of Smad3	1	0.03	0.44	0
14	INT269921	Binding of Smad3 and Scn4a	1	0.12	0	0
15	INT269942	Sox17 Regulation of Smad3	1	0.37	0.12	0
16	INT269929	Binding of Cdkn2b and Smad3	1	0.18	0.89	0
17	INT269935	Binding of Smad3 and Scn5a	1	0.13	0	0
18	INT269930	Binding of Smad3 and Sox17	1	0.40	1.16	0
19	INT269958	Sox17 Negative_regulation of Binding of Cdkn2b and Smad3	1	0.25	0.3	0
20	INT269946	Binding of Smad3 and Gopc	1	0.08	0	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 17127. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 17127. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT184720	Negative_regulation of Smad3	8	0.55	5.23	1.1
2	INT140794	Gene_expression of Smad3	22	0.64	9.41	0.83
3	INT157804	Phosphorylation of Smad3	18	0.77	8.15	0.35
4	INT140795	Positive_regulation of Gene_expression of Smad3	3	0.48	3.16	0.3
5	INT262797	Regulation of Gene_expression of Smad3	2	0.34	2.27	0.25
6	INT157797	Negative_regulation of Phosphorylation of Smad3	3	0.40	0.95	0.17
7	INT265317	Negative_regulation of Gene_expression of Smad3	2	0.41	0.9	0.06
8	INT262799	Localization of Smad3	6	0.56	2.09	0.04
9	INT184722	Positive_regulation of Smad3	3	0.47	1.22	0.03
10	INT254812	Positive_regulation of Phosphorylation of Smad3	1	0.25	0.94	0.03
11	INT254805	Transcription of Smad3	1	0.28	0.76	0.03
12	INT265337	Binding of Smad3	2	0.35	1	0
13	INT269913	Positive_regulation of Binding of Smad3	1	0.34	0.3	0
14	INT269873	Positive_regulation of Negative_regulation of Smad3	1	0.34	0.31	0
15	INT254809	Positive_regulation of Transcription of Smad3	1	0.25	0.24	0