G:18439

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Official Symbol P2rx7
Aliases P2X7R, P2X(7), AI467586
EntrezGene 18439
UniProt Coming Soon
Unique Molecular Interactions 29
Total Molecular Interactions 34
Total Single Events 326
Unique Interaction Partners 19

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to P2rx7. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to P2rx7. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to P2rx7. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT151779 Calca Positive_regulation of Transcription of P2rx7 1 0.02 0.54 0.87
2 INT205706 P2rx7 Regulation of Gene_expression of Il18 1 0.21 1.35 0.7
3 INT205702 P2rx7 Regulation of Gene_expression of Il1 1 0.04 1.38 0.67
4 INT205705 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of Il6 1 0.07 1.42 0.58
5 INT216941 P2rx7 Regulation of Ryr1 1 0.01 0.55 0.52
6 INT205704 P2rx7 Regulation of Localization of Il18 1 0.09 0.67 0.35
7 INT205713 Positive_regulation of P2rx7 Positive_regulation of Gene_expression of IL8 1 0.03 0.77 0.33
8 INT217025 P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
9 INT217024 Regulation of P2rx7 Regulation of Gene_expression of Ik 1 0.00 0.25 0.33
10 INT205703 P2rx7 Regulation of Positive_regulation of Casp1 1 0.11 0.66 0.33
11 INT205711 P2rx7 Regulation of Localization of IL8 1 0.02 0.92 0.33
12 INT145682 Binding of P2rx4 and P2rx7 2 0.25 0.36 0.31
13 INT205701 P2rx7 Positive_regulation of Il1 1 0.04 0.8 0.25
14 INT216911 Positive_regulation of P2rx7 Positive_regulation of Localization of Plg 1 0.02 0.13 0.23
15 INT216946 P2rx7 Regulation of Il10 1 0.28 0.17 0.21
16 INT205710 CAMP Positive_regulation of P2rx7 1 0.02 0.47 0.19
17 INT270827 P2rx7 Positive_regulation of Localization of Panx1 1 0.41 0.18 0.13
18 INT216945 Positive_regulation of P2rx7 Positive_regulation of Positive_regulation of Casp1 1 0.14 0.18 0.12
19 INT205708 Binding of Icam1 and P2rx7 1 0.08 1.03 0.09
20 INT217036 IRF6 Positive_regulation of Gene_expression of P2rx7 1 0.02 0 0.09
21 INT270824 Binding of P2rx7 and Panx1 1 0.34 0.15 0.09
22 INT304464 Binding of P2rx7 and P2rx6 1 0.05 0 0.09
23 INT243156 Positive_regulation of P2rx7 Positive_regulation of NOS1 1 0.00 0.08 0.08
24 INT270829 P2rx7 Positive_regulation of Panx1 1 0.66 0.08 0.08
25 INT270835 Positive_regulation of P2rx7 Positive_regulation of Localization of DPEP1 1 0.04 0.08 0.07
26 INT270825 P2rx7 Positive_regulation of Slc37a4 1 0.01 0 0.04
27 INT217031 Binding of P2rx7 and Positive_regulation of Casp1 1 0.02 0 0
28 INT217032 Binding of P2rx7 and Positive_regulation of Il1 1 0.02 0 0
29 INT216942 Positive_regulation of P2rx7 Positive_regulation of Casp1 1 0.14 0 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 18439. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 18439. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT88327 Gene_expression of P2rx7 109 0.77 48.86 22.41
2 INT121241 Positive_regulation of P2rx7 65 0.69 40.94 13.59
3 INT88326 Negative_regulation of P2rx7 16 0.58 8.77 6.25
4 INT145680 Regulation of P2rx7 22 0.61 11.92 5.42
5 INT144830 Positive_regulation of Gene_expression of P2rx7 22 0.68 9.78 3.92
6 INT144828 Binding of P2rx7 19 0.47 7.84 3.16
7 INT144829 Localization of P2rx7 12 0.79 2.92 2.12
8 INT216936 Negative_regulation of Gene_expression of P2rx7 5 0.42 2.59 1.84
9 INT125735 Transcription of P2rx7 3 0.62 1.34 1.58
10 INT205691 Regulation of Gene_expression of P2rx7 5 0.44 3.25 1.42
11 INT205690 Positive_regulation of Positive_regulation of P2rx7 14 0.68 6.26 1.3
12 INT151776 Positive_regulation of Transcription of P2rx7 1 0.03 0.53 0.86
13 INT125734 Negative_regulation of Transcription of P2rx7 1 0.38 0.81 0.67
14 INT121239 Regulation of Positive_regulation of P2rx7 2 0.61 1.32 0.32
15 INT216937 Regulation of Binding of P2rx7 1 0.44 0.08 0.29
16 INT216938 Negative_regulation of Localization of P2rx7 1 0.37 0.25 0.24
17 INT216940 Negative_regulation of Binding of P2rx7 1 0.37 0.15 0.2
18 INT216889 Phosphorylation of P2rx7 1 0.23 0 0.18
19 INT270813 Positive_regulation of Localization of P2rx7 1 0.46 0.24 0.15
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