G:242202

Official Symbol Pde5a Aliases Cn5n, Pde5, Cgbpde, Pde5a1 EntrezGene 242202 UniProt Coming Soon

Unique Molecular Interactions 14 Total Molecular Interactions 17 Total Single Events 146 Unique Interaction Partners 8

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to Pde5a. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to Pde5a. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to Pde5a. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT221257	Pde5a Positive_regulation of PRKG1	3	0.07	0.19	0.86
2	INT257222	Binding of Ltp and Pde5a	2	0.07	0.14	0.75
3	INT257229	Binding of PRKG1 and Pde5a	1	0.01	0.17	0.41
4	INT221259	Pde5a Positive_regulation of Localization of PRKG1	1	0.00	0.06	0.37
5	INT275094	Pde5a Regulation of Ltp	1	0.05	0	0.35
6	INT257224	Pde5a Positive_regulation of Phosphorylation of Creb1	1	0.03	0.09	0.2
7	INT202297	Pde5a Positive_regulation of Prkg1	1	0.00	0.13	0.18
8	INT257217	Binding of Pde2a and Pde5a	1	0.03	0	0.1
9	INT257221	Negative_regulation of Binding of Src and Pde5a	1	0.03	0	0.08
10	INT257219	Binding of Src and Pde5a	1	0.02	0	0.08
11	INT275090	Twist1 Positive_regulation of Gene_expression of Pde5a	1	0.02	0.62	0.04
12	INT275095	Twist1 Positive_regulation of Pde5a	1	0.03	0.62	0.04
13	INT313871	Pde5a Positive_regulation of Pah	1	0.49	0.97	0
14	INT275091	Negative_regulation of Twist1 Positive_regulation of Pde5a	1	0.02	0.06	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 242202. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 242202. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT209	Positive_regulation of Pde5a	30	0.21	2.54	16.31
2	INT95207	Negative_regulation of Pde5a	46	0.58	32.01	10.14
3	INT73128	Regulation of Pde5a	7	0.37	4.42	4.27
4	INT73127	Gene_expression of Pde5a	18	0.76	5.25	3.31
5	INT108422	Binding of Pde5a	11	0.36	3.07	2.07
6	INT73126	Positive_regulation of Gene_expression of Pde5a	3	0.59	0.55	1.31
7	INT257200	Phosphorylation of Pde5a	1	0.25	0	0.94
8	INT177532	Localization of Pde5a	2	0.56	0.96	0.81
9	INT257202	Protein_catabolism of Pde5a	2	0.38	0.36	0.66
10	INT208	Negative_regulation of Positive_regulation of Pde5a	3	0.17	2.02	0.65
11	INT275071	Negative_regulation of Protein_catabolism of Pde5a	1	0.17	0.36	0.6
12	INT257211	Negative_regulation of Localization of Pde5a	1	0.13	0.2	0.48
13	INT275073	Positive_regulation of Negative_regulation of Pde5a	1	0.22	0.45	0.3
14	INT42375	Positive_regulation of Positive_regulation of Pde5a	2	0.14	0.1	0.19
15	INT42376	Regulation of Positive_regulation of Pde5a	1	0.03	0	0.18
16	INT177528	Negative_regulation of Binding of Pde5a	1	0.34	0.46	0.15
17	INT275069	Negative_regulation of Gene_expression of Pde5a	1	0.26	0.54	0.13
18	INT257205	Transcription of Pde5a	1	0.21	0	0.08
19	INT323262	Negative_regulation of Negative_regulation of Pde5a	1	0.03	1.32	0.04