G:3091

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Official Symbol HIF1A
Aliases HIF1, MOP1, PASD8, bHLHe78, HIF-1alpha, HIF1-ALPHA
EntrezGene 3091
UniProt Coming Soon
Unique Molecular Interactions 45
Total Molecular Interactions 55
Total Single Events 405
Unique Interaction Partners 25

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to HIF1A. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to HIF1A. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to HIF1A. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT100369 HIF1A Positive_regulation of Positive_regulation of VEGFA 1 0.29 0.99 0.62
2 INT254360 Binding of EPAS1 and HIF1A 3 0.39 3.36 0.46
3 INT198647 TNF Positive_regulation of HIF1A 1 0.03 2.97 0.34
4 INT254349 Positive_regulation of Binding of EPAS1 and HIF1A 1 0.00 0.92 0.23
5 INT162850 ISYNA1 Positive_regulation of Localization of HIF1A 1 0.05 0.25 0.21
6 INT305003 HIF1A Regulation of SERPINE1 1 0.11 2.3 0.19
7 INT198649 Binding of HIF1A and MIF 1 0.01 1.53 0.18
8 INT143440 HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.52 0.45 0.17
9 INT181898 Binding of ROS1 and Positive_regulation of HIF1A 1 0.02 0.82 0.15
10 INT181897 ROS1 Negative_regulation of HIF1A 1 0.03 0.83 0.15
11 INT181895 ROS1 Positive_regulation of HIF1A 1 0.03 0.78 0.15
12 INT181894 ROS1 Regulation of HIF1A 1 0.02 0.82 0.13
13 INT198671 HIF1A Regulation of Positive_regulation of Epo 1 0.00 1.37 0.13
14 INT305002 Binding of HIF1A and SERPINE1 1 0.07 1.17 0.11
15 INT199583 HIF1A Positive_regulation of Gene_expression of Vhl 1 0.26 1.39 0.11
16 INT312305 Binding of HIF1A and Positive_regulation of Transcription of VEGFA 1 0.17 2.8 0.1
17 INT102244 IL36RN Positive_regulation of Binding of HIF1A 1 0.06 1.07 0.1
18 INT102245 TNF Positive_regulation of Binding of HIF1A 1 0.18 1.09 0.1
19 INT102248 INS Positive_regulation of Binding of HIF1A 1 0.13 0.96 0.1
20 INT294455 KLK4 Negative_regulation of HIF1A 1 0.01 0 0.1
21 INT102246 Binding of HIF1A and INS 1 0.07 0.96 0.1
22 INT173061 Binding of HIF1A and LILRA3 1 0.03 1.24 0.09
23 INT173062 Binding of HIF1A and VHLL 1 0.04 1.26 0.09
24 INT173057 Positive_regulation of HIF1A Positive_regulation of Gene_expression of VEGFA 1 0.24 1.49 0.08
25 INT178081 Negative_regulation of EDN1 Positive_regulation of HIF1A 1 0.04 1.18 0.08
26 INT178078 Positive_regulation of Binding of DBP and HIF1A 1 0.00 1 0.08
27 INT178080 EDN1 Positive_regulation of HIF1A 1 0.05 1.05 0.08
28 INT178060 EDN1 Positive_regulation of EDN1 Positive_regulation of HIF1A 1 0.03 1.13 0.08
29 INT178103 Binding of DBP and HIF1A 1 0.00 0.99 0.07
30 INT102247 Binding of EPO and HIF1A 1 0.41 0.65 0.04
31 INT173060 Negative_regulation of VHLL Positive_regulation of Positive_regulation of HIF1A 1 0.04 0.66 0.04
32 INT189554 Binding of HIF1A and Positive_regulation of EGLN1 1 0.04 0.86 0
33 INT143438 HIF1A Regulation of Gene_expression of VEGFA 1 0.69 0.13 0
34 INT315543 NARFL Regulation of Gene_expression of HIF1A 1 0.01 0.63 0
35 INT241307 Positive_regulation of HIF1A Positive_regulation of Positive_regulation of EPO 1 0.12 0.64 0
36 INT290478 Mitf Positive_regulation of HIF1A 1 0.57 0.61 0
37 INT189552 EGLN1 Positive_regulation of HIF1A 1 0.05 0.98 0
38 INT337352 Binding of ARNT and HIF1A 1 0.14 0.61 0
39 INT119045 HIF1A Regulation of Regulation of TP53 1 0.09 1.06 0
40 INT119046 HIF1A Regulation of TP53 1 0.05 1.06 0
41 INT143439 Positive_regulation of HIF1A Regulation of Gene_expression of VEGFA 1 0.30 0.13 0
42 INT290479 Binding of HIF1A and Mitf 1 0.30 1.29 0
43 INT119044 HIF1A Regulation of TCEAL1 1 0.02 1.06 0
44 INT313884 XRCC1 Positive_regulation of Localization of HIF1A 1 0.00 0.65 0
45 INT119047 HIF1A Regulation of Regulation of TCEAL1 1 0.08 1.06 0
46 INT345487 HIF1A Positive_regulation of PMAIP1 1 0.27 1.23 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3091. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3091. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT105387 Gene_expression of HIF1A 116 0.77 98.62 14.66
2 INT100379 Positive_regulation of HIF1A 69 0.69 57.31 10.4
3 INT112365 Regulation of HIF1A 27 0.60 21.24 3.05
4 INT105390 Positive_regulation of Gene_expression of HIF1A 27 0.49 26.3 2.88
5 INT100381 Positive_regulation of Positive_regulation of HIF1A 12 0.49 12.05 2.17
6 INT112364 Negative_regulation of HIF1A 22 0.57 16.95 2.13
7 INT119048 Negative_regulation of Gene_expression of HIF1A 10 0.57 9.23 1.5
8 INT143443 Localization of HIF1A 14 0.78 10.93 1.49
9 INT102249 Binding of HIF1A 39 0.36 30.47 1.04
10 INT155352 Phosphorylation of HIF1A 3 0.79 3.34 0.83
11 INT100378 Protein_catabolism of HIF1A 7 0.96 5.05 0.8
12 INT169731 Negative_regulation of Localization of HIF1A 1 0.57 0.57 0.73
13 INT100380 Negative_regulation of Positive_regulation of HIF1A 2 0.57 1.6 0.72
14 INT128795 Regulation of Positive_regulation of HIF1A 2 0.61 0.95 0.67
15 INT100382 Positive_regulation of Protein_catabolism of HIF1A 2 0.45 1.75 0.64
16 INT100377 Negative_regulation of Protein_catabolism of HIF1A 1 0.57 0.9 0.63
17 INT112363 Regulation of Gene_expression of HIF1A 6 0.60 2.28 0.61
18 INT155353 Positive_regulation of Phosphorylation of HIF1A 1 0.49 2.58 0.61
19 INT173105 Transcription of HIF1A 6 0.67 4.47 0.28
20 INT173103 Positive_regulation of Transcription of HIF1A 3 0.49 2.11 0.21
21 INT105392 Positive_regulation of Binding of HIF1A 5 0.45 3.83 0.1
22 INT143444 Positive_regulation of Localization of HIF1A 3 0.45 1.26 0.06
23 INT155174 Regulation of Regulation of HIF1A 3 0.24 1.57 0.04
24 INT173079 Positive_regulation of Regulation of HIF1A 1 0.26 0.64 0.04
25 INT105389 Negative_regulation of Binding of HIF1A 4 0.42 3.2 0.03
26 INT189607 Regulation of Binding of HIF1A 2 0.06 1.49 0
27 INT189594 Negative_regulation of Transcription of HIF1A 1 0.05 0.94 0
28 INT189606 Regulation of Transcription of HIF1A 1 0.06 0.46 0
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