G:3552

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Official Symbol IL1A
Aliases IL1, IL-1A, IL1F1, IL1-ALPHA
EntrezGene 3552
UniProt Coming Soon
Unique Molecular Interactions 31
Total Molecular Interactions 36
Total Single Events 162
Unique Interaction Partners 23

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IL1A. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IL1A. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IL1A. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT8409 IL1A Positive_regulation of Positive_regulation of Vip 1 0.01 0.63 1.27
2 INT8410 IL1A Positive_regulation of Vip 1 0.02 0.68 1.05
3 INT306271 IL1A Positive_regulation of Gene_expression of IL6 1 0.30 0.85 0.8
4 INT306264 Binding of IL1A and MTX1 1 0.09 0.74 0.61
5 INT129911 Skiv2l Negative_regulation of Localization of IL1A 1 0.01 0.74 0.48
6 INT130723 Binding of IL1A and Il1rn 1 0.01 0.59 0.47
7 INT130724 Negative_regulation of Binding of IL1A and Il1rn 1 0.01 0.59 0.47
8 INT19476 Binding of IL1A and Il6 1 0.00 2.19 0.36
9 INT19477 Binding of IL1A and Csf2 1 0.00 2.19 0.36
10 INT164904 Binding of IL1A and IL33 1 0.39 0.19 0.35
11 INT113476 IL1A Positive_regulation of Localization of MMP14 1 0.10 0.22 0.34
12 INT97357 IL1A Positive_regulation of Transcription of Timp1 1 0.06 0.47 0.34
13 INT92870 SON Regulation of IL1A 1 0.01 0.31 0.32
14 INT97358 IL1A Regulation of Timp1 1 0.04 0.51 0.31
15 INT102872 IL1A Negative_regulation of Transcription of IL6 1 0.43 0.42 0.31
16 INT80288 IL1A Positive_regulation of CCL13 1 0.17 0.39 0.24
17 INT80280 IL1A Positive_regulation of CCL7 1 0.19 0.39 0.24
18 INT80284 IL1A Positive_regulation of Gene_expression of CCL13 1 0.58 0.39 0.24
19 INT209856 IL1A Negative_regulation of Transcription of CD36 1 0.26 0.1 0.22
20 INT102870 PTGER2 Regulation of IL1A 1 0.11 0.28 0.2
21 INT102868 TNF Regulation of IL1A 1 0.27 0.28 0.2
22 INT102873 IL1A Regulation of Gene_expression of IL6 1 0.27 0.28 0.2
23 INT190381 IL1A Regulation of Transcription of DEFB4A 1 0.06 0.93 0.18
24 INT164894 Binding of IL1A and IL1RAP 1 0.08 0.1 0.18
25 INT214380 Binding of IL1A and PRTN3 1 0.00 0.94 0.18
26 INT81992 IL1A Positive_regulation of Positive_regulation of Tnfsf11 1 0.05 0.27 0.13
27 INT81983 IL1A Positive_regulation of Positive_regulation of PTGS2 1 0.01 0.27 0.13
28 INT294438 KLK4 Negative_regulation of IL1A 1 0.00 0 0.1
29 INT190382 IL1A Regulation of Regulation of DEFB4A 1 0.06 0.57 0.1
30 INT16444 IGHG3 Negative_regulation of Binding of IL1A 1 0.11 0.42 0.09
31 INT16442 Binding of IGHG3 and IL1A 1 0.10 0.36 0.05

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3552. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3552. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT16445 Gene_expression of IL1A 60 0.78 44.46 19.19
2 INT19475 Positive_regulation of IL1A 20 0.67 17.99 7.57
3 INT58468 Negative_regulation of Gene_expression of IL1A 10 0.58 9.39 5.57
4 INT69310 Negative_regulation of IL1A 10 0.43 7.83 5.05
5 INT59083 Positive_regulation of Gene_expression of IL1A 11 0.70 9.09 4.48
6 INT19189 Localization of IL1A 14 0.78 9.02 3.78
7 INT16447 Binding of IL1A 10 0.45 4.01 2.78
8 INT89926 Regulation of IL1A 10 0.60 7.12 1.72
9 INT59082 Regulation of Gene_expression of IL1A 3 0.45 2.07 1.2
10 INT16446 Transcription of IL1A 4 0.69 1.76 0.96
11 INT83454 Positive_regulation of Negative_regulation of IL1A 1 0.50 0.62 0.81
12 INT83453 Negative_regulation of Localization of IL1A 1 0.43 0.39 0.69
13 INT82758 Positive_regulation of Positive_regulation of IL1A 1 0.45 1.06 0.27
14 INT159502 Positive_regulation of Transcription of IL1A 1 0.45 0.35 0.25
15 INT159501 Regulation of Transcription of IL1A 1 0.44 0.35 0.25
16 INT16448 Negative_regulation of Binding of IL1A 1 0.40 0.41 0.08
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