G:3592

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Official Symbol IL12A
Aliases P35, CLMF, NFSK, NKSF1, IL-12A
EntrezGene 3592
UniProt Coming Soon
Unique Molecular Interactions 63
Total Molecular Interactions 89
Total Single Events 471
Unique Interaction Partners 37

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to IL12A. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to IL12A. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to IL12A. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT69030 IL18 Positive_regulation of IL12A 3 0.31 5.57 2.72
2 INT350148 Binding of IL12A and ERAL1 1 0.21 8.23 2.26
3 INT69031 IL12A Positive_regulation of IFNA1 9 0.13 4.23 1.52
4 INT87026 ZAK Positive_regulation of Gene_expression of IL12A 3 0.12 2.55 1.26
5 INT70046 IL12A Regulation of IL10 1 0.07 1.42 1.21
6 INT70045 IL12A Regulation of Negative_regulation of PRF1 1 0.04 1.42 1.21
7 INT70044 IL12A Regulation of PRF1 1 0.04 1.42 1.21
8 INT70034 IL12A Regulation of Negative_regulation of IL10 1 0.07 1.42 1.21
9 INT176365 IL12A Positive_regulation of Gene_expression of IFNA1 1 0.13 1.35 0.6
10 INT283980 Binding of IL12A and IL23A 2 0.24 1.33 0.57
11 INT176371 LBR Positive_regulation of IL12A 1 0.04 1.22 0.55
12 INT176364 IL12A Regulation of Positive_regulation of IFNA1 1 0.12 0.59 0.46
13 INT95564 Positive_regulation of HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
14 INT95562 HRAS Positive_regulation of IL12A 1 0.03 0.7 0.45
15 INT329794 TLR2 Positive_regulation of Positive_regulation of IL12A 1 0.01 1.05 0.44
16 INT292887 IL4 Regulation of IL12A 1 0.01 0.25 0.39
17 INT292889 IL2 Regulation of IL12A 1 0.01 0.25 0.39
18 INT292888 TNF Regulation of IL12A 1 0.02 0.25 0.39
19 INT267595 IL12A Positive_regulation of IFN1@ 1 0.03 0.69 0.36
20 INT267589 IL2 Positive_regulation of Gene_expression of IL12A 1 0.01 0.69 0.34
21 INT73494 PTGER2 Positive_regulation of Gene_expression of IL12A 1 0.05 0.51 0.33
22 INT73493 PTGER2 Negative_regulation of Gene_expression of IL12A 1 0.04 0.51 0.33
23 INT221417 IL12A Positive_regulation of Binding of IFN1@ 1 0.14 0.98 0.33
24 INT120855 PRL Positive_regulation of Localization of IL12A 1 0.43 0.5 0.26
25 INT304582 IL12A Positive_regulation of Gene_expression of TH1L 1 0.21 0.83 0.25
26 INT304580 IL12A Regulation of Gene_expression of TH1L 1 0.19 0.82 0.25
27 INT225652 Gene_expression of IL4 Positive_regulation of Positive_regulation of IL12A 1 0.06 1.2 0.25
28 INT189142 MTNR1B Positive_regulation of Gene_expression of IL12A 1 0.01 0.29 0.24
29 INT343914 Hmgb1 Positive_regulation of Gene_expression of IL12A 1 0.01 0.41 0.24
30 INT343911 Mthfd1 Positive_regulation of Gene_expression of IL12A 1 0.00 0.41 0.23
31 INT350146 Binding of IL12A and RS1 1 0.01 0.97 0.23
32 INT325314 Binding of IL12A and STAT3 1 0.19 0.6 0.22
33 INT325317 Binding of IL12A and TH1L 1 0.18 0.59 0.22
34 INT104833 IGKV2OR2-1 Negative_regulation of Gene_expression of IL12A 1 0.00 0 0.22
35 INT252821 Binding of CD4 and IL12A 1 0.02 1.36 0.19
36 INT252817 Binding of CD8A and IL12A 1 0.02 1.36 0.19
37 INT252788 Binding of IL12A and IL18 1 0.01 1.33 0.19
38 INT323134 Binding of IL10 and IL12A 1 0.06 0.55 0.18
39 INT104827 IRF6 Positive_regulation of IL12A 2 0.07 0.13 0.16
40 INT273251 Binding of IL6 and IL12A 1 0.00 1.15 0.16
41 INT224797 IL12A Regulation of Gene_expression of TNF 1 0.26 1.59 0.15
42 INT274474 IL12A Regulation of Gene_expression of VEGFA 1 0.04 0.36 0.14
43 INT274472 IL12A Negative_regulation of Gene_expression of FGF2 1 0.02 0.36 0.14
44 INT330467 IL12A Positive_regulation of Localization of TH1L 1 0.16 0.3 0.14
45 INT274473 IL12A Regulation of Gene_expression of FGF2 1 0.02 0.36 0.14
46 INT292628 IL12A Positive_regulation of Gene_expression of IL9 1 0.07 0.15 0.12
47 INT303989 Lep Positive_regulation of IL12A 1 0.05 0.39 0.11
48 INT274471 IL12A Negative_regulation of Gene_expression of IL10 1 0.02 0.99 0.1
49 INT274470 Binding of IL12A and GOPC 1 0.02 0.6 0.09
50 INT194828 IL12A Positive_regulation of Phosphorylation of Stat4 1 0.03 0.08 0.09
51 INT292629 IL21 Positive_regulation of IL12A 1 0.06 0.05 0.06
52 INT292624 IL21 Positive_regulation of Binding of IL12A 1 0.06 0.05 0.06
53 INT274469 IL12A Positive_regulation of Gene_expression of IL6 1 0.04 1.39 0.06
54 INT110751 IL12A Negative_regulation of KRR1 1 0.64 0.57 0.05
55 INT194665 IL12A Positive_regulation of MAPK1 1 0.06 0 0.05
56 INT294771 IL6 Positive_regulation of IL12A 1 0.05 0.15 0.04
57 INT285863 Positive_regulation of IL12A Regulation of TH1L 1 0.01 0.25 0.04
58 INT303996 Lep Positive_regulation of Gene_expression of IL12A 1 0.08 0.29 0.04
59 INT194679 IL12A Positive_regulation of GADD45A 1 0.04 0 0.04
60 INT285864 IL12A Regulation of TH1L 1 0.00 0.25 0.04
61 INT225648 IL4 Positive_regulation of Gene_expression of IL12A 1 0.06 0.89 0.03
62 INT300079 IL12A Positive_regulation of Positive_regulation of IFNA1 1 0.05 2.14 0
63 INT300063 IL12A Positive_regulation of IL12A Positive_regulation of IFNA1 1 0.03 2.14 0
64 INT274475 IL12A Regulation of Gene_expression of IL6 1 0.04 0.68 0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3592. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3592. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT61619 Gene_expression of IL12A 194 0.77 146.07 41.97
2 INT61624 Positive_regulation of Gene_expression of IL12A 50 0.56 33.07 13.07
3 INT95565 Positive_regulation of IL12A 47 0.56 33.96 10.16
4 INT91667 Localization of IL12A 39 0.74 25.51 7.36
5 INT83119 Negative_regulation of Gene_expression of IL12A 24 0.42 17.52 5.69
6 INT98251 Binding of IL12A 20 0.37 16.03 4.51
7 INT70051 Transcription of IL12A 7 0.25 5.61 3.39
8 INT78467 Negative_regulation of IL12A 18 0.38 11.29 2.98
9 INT105378 Regulation of IL12A 6 0.26 8.82 2.15
10 INT91663 Positive_regulation of Localization of IL12A 9 0.27 5.91 1.95
11 INT91659 Negative_regulation of Localization of IL12A 8 0.14 3.9 1.75
12 INT95566 Positive_regulation of Positive_regulation of IL12A 10 0.41 7.47 1.43
13 INT77947 Regulation of Gene_expression of IL12A 6 0.24 5.23 0.94
14 INT95567 Negative_regulation of Positive_regulation of IL12A 2 0.34 1.83 0.59
15 INT226482 Phosphorylation of IL12A 3 0.10 1.47 0.57
16 INT290393 Regulation of Localization of IL12A 1 0.16 1.02 0.48
17 INT301687 Negative_regulation of Phosphorylation of IL12A 1 0.05 0.94 0.37
18 INT77946 Positive_regulation of Transcription of IL12A 1 0.24 0 0.24
19 INT323145 Regulation of Positive_regulation of IL12A 1 0.12 0.42 0.11
20 INT274483 Positive_regulation of Binding of IL12A 1 0.16 1.08 0.05
21 INT274486 Protein_catabolism of IL12A 1 0.28 0.98 0
22 INT300093 Positive_regulation of Negative_regulation of IL12A 1 0.26 1.28 0
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