G:361

Official Symbol AQP4 Aliases MIWC, HMIWC2, MGC22454 EntrezGene 361 UniProt Coming Soon

Unique Molecular Interactions 22 Total Molecular Interactions 48 Total Single Events 317 Unique Interaction Partners 14

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to AQP4. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to AQP4. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to AQP4. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT206764	Binding of AQP4 and Nqo1	8	0.05	13.45	2.84
2	INT250253	Binding of AQP4 and SLC1A2	1	0.30	2.95	1.09
3	INT250248	Binding of AQP4 and SLC1A3	1	0.11	1.55	0.77
4	INT334153	Binding of AQP4 and CSF2	1	0.16	3	0.75
5	INT250247	FCGR3A Negative_regulation of AQP4	1	0.01	0.87	0.62
6	INT169648	IGHG3 Regulation of AQP4	3	0.02	4.63	0.55
7	INT235975	Binding of AQP4 and IgG	2	0.04	4.11	0.53
8	INT157343	Binding of AQP4 and HLA-DPB1	1	0.30	0.89	0.43
9	INT250250	Gene_expression of AQP4 Positive_regulation of Gene_expression of SLC1A2	1	0.37	1.1	0.39
10	INT250242	Binding of AQP4 and GOPC	1	0.06	0.39	0.35
11	INT308701	Binding of AQP4 and DDX41	1	0.15	3.53	0.32
12	INT235977	Binding of AQP4 and Ighg1	1	0.03	1.31	0.3
13	INT308708	DDX41 Regulation of AQP4	1	0.10	2.79	0.26
14	INT327791	Binding of AQP4 and Alms1	1	0.03	1.1	0.17
15	INT250241	SLC1A3 Positive_regulation of AQP4	1	0.13	0.21	0.16
16	INT250246	SLC1A2 Positive_regulation of AQP4	1	0.13	0.22	0.16
17	INT308709	Positive_regulation of Binding of AQP4 and DDX41	1	0.18	1.19	0.14
18	INT250244	Binding of AQP4 and Positive_regulation of SLC1A3	1	0.14	0.69	0.08
19	INT308706	Binding of AQP4 and M1	1	0.06	0.86	0
20	INT308702	Binding of AQP4 and CD40LG	1	0.10	0	0
21	INT308703	Positive_regulation of Binding of AQP4 and M1	1	0.08	0.61	0
22	INT308707	Binding of AQP4 and IGHG3	1	0.01	0.88	0

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 361. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 361. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT140413	Gene_expression of AQP4	113	0.78	139.25	25.53
2	INT250282	Negative_regulation of AQP4	32	0.54	32.96	9.07
3	INT157959	Binding of AQP4	32	0.48	43.44	7.44
4	INT157960	Regulation of AQP4	11	0.48	21.36	3.06
5	INT169747	Localization of AQP4	17	0.75	16.64	2.79
6	INT140414	Positive_regulation of AQP4	25	0.64	23.43	2.47
7	INT250272	Positive_regulation of Gene_expression of AQP4	11	0.54	9.79	1.85
8	INT251679	Negative_regulation of Gene_expression of AQP4	2	0.38	10.37	0.77
9	INT327779	Regulation of Gene_expression of AQP4	5	0.48	4.5	0.6
10	INT327785	Transcription of AQP4	3	0.56	2.19	0.23
11	INT250270	Regulation of Localization of AQP4	1	0.41	0.22	0.2
12	INT327780	Negative_regulation of Negative_regulation of AQP4	1	0.33	1.12	0.18
13	INT250280	Positive_regulation of Negative_regulation of AQP4	1	0.37	0.58	0.17
14	INT250279	Positive_regulation of Localization of AQP4	1	0.46	0.69	0.13
15	INT327778	Positive_regulation of Regulation of AQP4	1	0.37	2.84	0.07
16	INT327783	Regulation of Transcription of AQP4	1	0.35	1.03	0
17	INT327788	Regulation of Regulation of AQP4	1	0.21	0.75	0