G:3716

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{| style="color: black; background-color: white; float:right;"
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{| cellpadding=7 cellspacing=3 style="align: right;"
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! style="color: black; background:#AAFCFB; "| Official Symbol
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| style="color: black; background:#F1FEFE; " align="center"| JAK1
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|-
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! style="color: black; background:#AAFCFB;"| Aliases
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| style="color: black; background:#F1FEFE;"  align="center"| JTK3, JAK1A, JAK1B
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! style="color: black; background:#AAFCFB;"| EntrezGene
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| style="color: black; background:#F1FEFE;"  align="center"| [http://www.ncbi.nlm.nih.gov/gene?term=3716 3716]
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|-
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! style="color: black; background:#AAFCFB;"| UniProt
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| style="color: black; background:#F1FEFE;"  align="center"| Coming Soon
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{| cellpadding=7 cellspacing=3 style="align: right;"
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! style="color: black; background:#AAFCFB; "| Unique Molecular Interactions
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| style="color: black; background:#F1FEFE; "  align="center"| 10
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! style="color: black; background:#AAFCFB;"| Total Molecular Interactions
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| style="color: black; background:#F1FEFE; "  align="center"| 11
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|-
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! style="color: black; background:#AAFCFB; "| Total Single Events
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| style="color: black; background:#F1FEFE;" align="center"| 69
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! style="color: black; background:#AAFCFB; "| Unique Interaction Partners
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| style="color: black; background:#F1FEFE; " align="center"| 9
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|}
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|}
 
This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to JAK1. 'Self' interactions are filtered out.
 
This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to JAK1. 'Self' interactions are filtered out.
  
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT231534]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT231534]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''JAK1'''</span> and  <span style="color:#800000">'''SOAT1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span> and  <span style="color:#800000">'''[[G:6646|<span style="color:#800000">SOAT1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.01
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT234607]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT234607]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''Socs3'''</span> <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''[[G:12702|<span style="color:#800000">Socs3</span>]]'''</span> <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.01
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT237369]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT237369]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''SOAT1'''</span> <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#000080">'''Phosphorylation'''</span> of <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''[[G:6646|<span style="color:#800000">SOAT1</span>]]'''</span> <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Phosphorylation|<span style="color:#000080">Phosphorylation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT258398]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT258398]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''IL6R'''</span> and  <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:3570|<span style="color:#800000">IL6R</span>]]'''</span> and  <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.01
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.01
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 5
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 5
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT226339]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT226339]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''IK'''</span> and  <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:3550|<span style="color:#800000">IK</span>]]'''</span> and  <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT226366]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT226366]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''CISH'''</span> and  <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:1154|<span style="color:#800000">CISH</span>]]'''</span> and  <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
 
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 7
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 7
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT355019]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT355019]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''Lif'''</span> <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''[[G:60584|<span style="color:#800000">Lif</span>]]'''</span> <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT355022]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT355022]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''Cntf'''</span> <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''[[G:25707|<span style="color:#800000">Cntf</span>]]'''</span> <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.00
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 9
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 9
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT273369]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT273369]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''SOCS3'''</span> <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''[[G:9021|<span style="color:#800000">SOCS3</span>]]'''</span> <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.03
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.03
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT206088]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT206088]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''IL6'''</span> <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#800000">'''[[G:3569|<span style="color:#800000">IL6</span>]]'''</span> <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.18
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.18
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT118035]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT118035]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 23
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 23
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.67
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.67
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT100689]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT100689]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 8
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 8
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT206144]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT206144]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Phosphorylation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Phosphorylation|<span style="color:#000080">Phosphorylation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 6
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.57
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT155846]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT155846]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Transcription'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Transcription|<span style="color:#000080">Transcription</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 4
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 4
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.67
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.67
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 5
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 5
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT264129]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT264129]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Protein_catabolism'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Protein_catabolism|<span style="color:#000080">Protein_catabolism</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.02
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.02
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 6
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT226580]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT226580]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Localization'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Localization|<span style="color:#000080">Localization</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 3
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 3
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.11
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.11
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 7
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 7
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT279298]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT279298]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Gene_expression|<span style="color:#000080">Gene_expression</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 7
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 7
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.65
 
| style="color: black; background:#98FB98; border: 1px solid lightgray" align="center"| 0.65
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 8
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280551]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280551]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#000080">'''Gene_expression'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Gene_expression|<span style="color:#000080">Gene_expression</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.41
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.41
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 9
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 9
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT317742]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT317742]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#000080">'''Transcription'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Transcription|<span style="color:#000080">Transcription</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.49
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.49
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 10
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280561]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280561]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 2
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.26
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.26
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 11
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 11
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT293340]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT293340]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.02
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.02
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 12
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 12
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280557]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280557]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.30
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.30
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 13
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 13
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT206164]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT206164]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#000080">'''Phosphorylation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Phosphorylation|<span style="color:#000080">Phosphorylation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.19
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.19
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 14
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 14
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280558]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT280558]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#000080">'''Binding'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Binding|<span style="color:#000080">Binding</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.35
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.35
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 15
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 15
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT315883]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT315883]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.01
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.01
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| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 16
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray; white-space:nowrap;" align="center"| 16
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT144040]]
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| [[INT144040]]
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''Negative_regulation'''</span> of <span style="color:#000080">'''Positive_regulation'''</span> of <span style="color:#800000">'''JAK1'''</span>
+
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| <span style="color:#000080">'''[[E:Negative_regulation|<span style="color:#000080">Negative_regulation</span>]]'''</span> of <span style="color:#000080">'''[[E:Positive_regulation|<span style="color:#000080">Positive_regulation</span>]]'''</span> of <span style="color:#800000">'''[[G:3716|<span style="color:#800000">JAK1</span>]]'''</span>
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#F1FEFE; border: 1px solid lightgray" align="center"| 1
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.04
 
| style="color: black; background:#FFB6C1; border: 1px solid lightgray" align="center"| 0.04

Latest revision as of 13:44, 19 January 2013

Official Symbol JAK1
Aliases JTK3, JAK1A, JAK1B
EntrezGene 3716
UniProt Coming Soon
Unique Molecular Interactions 10
Total Molecular Interactions 11
Total Single Events 69
Unique Interaction Partners 9

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to JAK1. 'Self' interactions are filtered out.

[edit] Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to JAK1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to JAK1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Interaction String Documents TM Confidence Disease Relevance Pain Relevance
1 INT231534 Binding of JAK1 and SOAT1 1 0.01 0.6 0.64
2 INT234607 Socs3 Negative_regulation of JAK1 1 0.01 0.54 0.39
3 INT237369 SOAT1 Negative_regulation of Phosphorylation of JAK1 1 0.00 0 0.38
4 INT258398 Binding of IL6R and JAK1 1 0.01 0.75 0.23
5 INT226339 Binding of IK and JAK1 1 0.00 0.46 0.16
6 INT226366 Binding of CISH and JAK1 1 0.00 0.46 0.15
7 INT355019 Lif Positive_regulation of JAK1 1 0.00 0.69 0.08
8 INT355022 Cntf Positive_regulation of JAK1 1 0.00 0.69 0.08
9 INT273369 SOCS3 Negative_regulation of JAK1 1 0.03 0 0.07
10 INT206088 IL6 Positive_regulation of JAK1 1 0.18 0.05 0

[edit] Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 3716. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 3716. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No Page link Event String Documents TM Confidence Disease Relevance Pain Relevance
1 INT118035 Positive_regulation of JAK1 23 0.67 10.57 3.29
2 INT100689 Negative_regulation of JAK1 8 0.57 5.36 1.87
3 INT206144 Phosphorylation of JAK1 6 0.57 1.77 1.64
4 INT155846 Transcription of JAK1 4 0.67 1.93 1.19
5 INT264129 Protein_catabolism of JAK1 1 0.02 0.38 0.55
6 INT226580 Localization of JAK1 3 0.11 0.52 0.49
7 INT279298 Gene_expression of JAK1 7 0.65 5.5 0.37
8 INT280551 Negative_regulation of Gene_expression of JAK1 2 0.41 1.02 0.37
9 INT317742 Positive_regulation of Transcription of JAK1 1 0.49 0.57 0.35
10 INT280561 Binding of JAK1 2 0.26 0.39 0.26
11 INT293340 Negative_regulation of Negative_regulation of JAK1 1 0.02 0.34 0.1
12 INT280557 Negative_regulation of Binding of JAK1 1 0.30 0.4 0
13 INT206164 Positive_regulation of Phosphorylation of JAK1 1 0.19 0.19 0
14 INT280558 Positive_regulation of Binding of JAK1 1 0.35 0.39 0
15 INT315883 Positive_regulation of Positive_regulation of JAK1 1 0.01 0.38 0
16 INT144040 Negative_regulation of Positive_regulation of JAK1 1 0.04 0.08 0
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