G:5604

Official Symbol MAP2K1 Aliases MEK1, MKK1, MAPKK1, PRKMK1 EntrezGene 5604 UniProt Coming Soon

Unique Molecular Interactions 11 Total Molecular Interactions 12 Total Single Events 53 Unique Interaction Partners 9

This page displays the top molecular interactions and top single events that were mentioned in the literature that are relevant to MAP2K1. 'Self' interactions are filtered out.

Molecular Interactions

The table below shows the top 100 pain related interactions that have been reported that are relevant to MAP2K1. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to MAP2K1. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Interaction String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT124477	MAP2K1 Positive_regulation of Positive_regulation of MAPK1	1	0.12	1.35	0.65
2	INT124475	MAP2K1 Positive_regulation of Positive_regulation of CPOX	1	0.04	0.68	0.33
3	INT194699	MAP2K1 Positive_regulation of MAPK8	1	0.05	0	0.04
4	INT194703	MAP2K1 Positive_regulation of MAP2K6	1	0.21	0	0.04
5	INT194677	Binding of GADD45A and MAP2K1	1	0.27	0	0.04
6	INT194719	MAP2K1 Positive_regulation of MAPK1	1	0.27	0	0.04
7	INT194701	MAP2K1 Positive_regulation of MAP2K4	1	0.21	0	0.04
8	INT194732	MAP2K1 Positive_regulation of Gene_expression of MAPK1	1	0.27	0	0.04
9	INT194691	MAP2K1 Positive_regulation of MAP2K3	1	0.23	0	0.04
10	INT295479	PRKCA Positive_regulation of MAP2K1	1	0.14	0.35	0.03
11	INT295474	IRF6 Positive_regulation of MAP2K1	1	0.18	0.41	0.03

Single Events

The table below shows the top 100 pain related interactions that have been reported that are relevant to 5604. They are ordered first by their pain relevance and then by number of times they were reported that are relevant to 5604. Text mining (TM) confidence, disease relevance and pain relevance are highlighted in green if they are judged to be high and red if not. Please click on the 'INT' link to display more detailed information on each interaction.

Int No	Page link	Event String	Documents	TM Confidence	Disease Relevance	Pain Relevance
1	INT106065	Negative_regulation of MAP2K1	27	0.57	12.69	3.97
2	INT104121	Positive_regulation of MAP2K1	8	0.61	4.84	1.41
3	INT71782	Gene_expression of MAP2K1	7	0.68	3.17	1.37
4	INT71778	Positive_regulation of Gene_expression of MAP2K1	2	0.36	0.37	0.81
5	INT104120	Positive_regulation of Positive_regulation of MAP2K1	1	0.49	0	0.54
6	INT240205	Regulation of MAP2K1	3	0.26	0.44	0.28
7	INT215418	Positive_regulation of Phosphorylation of MAP2K1	1	0.03	0.51	0.08
8	INT215420	Phosphorylation of MAP2K1	1	0.05	0.51	0.08
9	INT329571	Binding of MAP2K1	2	0.11	0.4	0